Combating Doxorubicin-Resistant Acute Myeloid Leukemia

Oncotarget | May 23, 2024
In this new study, researchers examined the impact of MIA-602 as monotherapy and in combination with Doxorubicin on three Doxorubicin-resistant acute myeloid leukemia cell lines. continue reading »

SARS-CoV-2 Spike Protein Disrupts p53 Tumor Suppressor Pathway

Oncotarget | May 9, 2024
In this new study, researchers investigated the interplay between the SARS-CoV-2 spike protein and tumor suppressor gene p53. continue reading »

Synergistic Effects of Drug Combinations Targeting AML Cells

Oncotarget | April 11, 2024
In this new study, researchers investigated a promising new approach to acute myeloid leukemia (AML) therapy by combining multiple drugs to enhance cytotoxic effects on AML cells. continue reading »

When Does Human Life Truly Begin?

Aging | May 16, 2024
In this fascinating new review, researchers Polina A. Loseva and Vadim N. Gladyshev from Harvard Medical School discuss the beginning of becoming a human. continue reading »

UV-A Exposure, Cellular Senescence, and Vision Impairment

Aging | May 3, 2024
In this new study, researchers investigated the senescent phenotypes of human corneal endothelial cells upon UV-A exposure. continue reading »

First Evidence of a Pan-tissue Decline in Stemness During Human Aging

Aging | April 18, 2024
In this new study, researchers provide the first evidence of a pan-tissue decrease of stemness during human aging. continue reading »

The Role of CDKs in Breast Cancer Among Women in Pakistan

Genes & Cancer | October 28, 2022
Researchers examined the mRNA expression levels of six CDKs in Pakistani women with pre- and postmenopausal breast cancer with lung metastasis. continue reading »

Cell Cycle Mechanism as Potential Target to Treat Array of Cancers

Genes & Cancer | September 12, 2022
In a recently published Genes & Cancer review paper, researchers discuss the role of CDK4 in cell cycle control, normal development, tumorigenesis, and cancer therapeutics. continue reading »

Common Bacteria Associated With Gastric Cancer and New Biomarkers

Genes & Cancer | August 19, 2022
Researchers investigated the expression of two lncRNAs in gastric cancer tissues and evaluated their association with a common strain of bacteria. continue reading »