Oncotarget

Special Collection Oncotarget

COLLECTION OF ONCOTARGET (VOLUME 7, 2016) COVER PAPERS

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Table of Contents

Endosome and INPP4B

http://dx.doi.org/10.18632/oncotarget.6663
Chen Li Chew, Ming Chen, Pier Paolo Pandolfi

1-2
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BRCA somatic and germline mutation detection in paraffin embedded ovarian cancers by next-generation sequencing

http://dx.doi.org/10.18632/oncotarget.6834
Andrea Mafficini, Michele Simbolo, Alice Parisi, Borislav Rusev, Claudio Luchini, Ivana Cataldo, Elena Piazzola, Nicola Sperandio, Giona Turri, Massimo Franchi, Giampaolo Tortora, Chiara Bovo, Rita T. Lawlor, and Aldo Scarpa

1076-1083
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γKlotho is a novel marker and cell survival factor in a subset of triple negative breast cancers

http://dx.doi.org/10.18632/oncotarget.6006
Nuša Trošt, Samuel Peña-Llopis, Sajjan Koirala, Jurij Stojan, Patrick Ryan Potts, Klementina Fon Tacer, Elisabeth D. Martinez

2611-2628
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A multiplexed marker-based algorithm for diagnosis of carcinoma of unknown primary using circulating tumor cells

http://dx.doi.org/10.18632/oncotarget.6657
Elizabeth M. Matthew, Lanlan Zhou, Zhaohai Yang, David T. Dicker, Sheldon L. Holder, Bora Lim, Ramdane Harouaka, Si-Yang Zheng, Joseph J. Drabick, Nicholas E. Lamparella, Cristina I. Truica and Wafik S. El-Deiry

3662-3676
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Histone H3 lysine 4 acetylation and methylation dynamics define breast cancer subtypes

http://dx.doi.org/10.18632/oncotarget.6922
Terri L. Messier, Jonathan A. R. Gordon, Joseph R. Boyd, Coralee E. Tye, Gillian Browne, Janet L. Stein, Jane B. Lian and Gary S. Stein

5094-5109
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Disruption of KIF3A in patient-derived glioblastoma cells: effects on ciliogenesis, hedgehog sensitivity, and tumorigenesis

http://dx.doi.org/10.18632/oncotarget.6854
Lan B. Hoang-Minh, Loic P. Deleyrolle, Dorit Siebzehnrubl, George Ugartemendia, Hunter Futch, Benjamin Griffith, Joshua J. Breunig, Gabriel De Leon, Duane A. Mitchell, Susan Semple-Rowland, Brent A. Reynolds, Matthew R. Sarkisian

7029-7043
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Spatially- and temporally-controlled postnatal p53 knockdown cooperates with embryonic Schwann cell precursor Nf1 gene loss to promote malignant peripheral nerve sheath tumor formation

http://dx.doi.org/10.18632/oncotarget.7232
Angela C. Hirbe, Sonika Dahiya, Dinorah Friedmann-Morvinski, Inder M. Verma, D. Wade Clapp and David H. Gutmann

7403-7414
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Molecular signatures of age-associated chronic degeneration of shoulder muscles

http://dx.doi.org/10.18632/oncotarget.7382
Yotam Raz, Jan Ferdinand Henseler, Arjen Kolk, Zuotian Tatum, Niels Kuipers Groosjohan, Nisha E. Verwey, Wibowo Arindrarto, Szymon M. Kielbasa, Jochem Nagels, Peter A. C. ’t Hoen, Rob G. H. H. Nelissen and Vered Raz

8513-8523
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Lipid tethering of breast tumor cells enables real-time imaging of free-floating cell dynamics and drug response

http://dx.doi.org/10.18632/oncotarget.7251
Kristi R. Chakrabarti, James I. Andorko, Rebecca A. Whipple, Peipei Zhang, Elisabeth L. Sooklal, Stuart S. Martin, Christopher M. Jewell

10486-10497
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Brachyury identifies a class of enteroendocrine cells in normal human intestinal crypts and colorectal cancer

http://dx.doi.org/10.18632/oncotarget.7202
Jana Jezkova, Jason S. Williams, Filipe Pinto, Stephen J. Sammut, Geraint T. Williams, Simon Gollins, Ramsay J. McFarlane, Rui Manuel Reis, Jane A. Wakeman

11478-114866
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Cis-acting elements in its 3′ UTR mediate post-transcriptional regulation of KRAS

http://dx.doi.org/10.18632/oncotarget.7599
Minlee Kim, Nicole Kogan and Frank J. Slack

11770-11784
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Camptothecin targets WRN protein: mechanism and relevance in clinical breast cancer

http://dx.doi.org/10.18632/oncotarget.7906
Raghavendra A. Shamanna, Huiming Lu, Deborah L. Croteau, Arvind Arora, Devika Agarwal, Graham Ball, Mohammed A. Aleskandarany, Ian O. Ellis, Yves Pommier, Srinivasan Madhusudan and Vilhelm A. Bohr

13269-13284
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Sixth BHD Symposium and First International Upstate Kidney Cancer Symposium: latest scientific and clinical discoveries

http://dx.doi.org/10.18632/oncotarget.7733
Gennady Bratslavsky, Mark R. Woodford, Michael Daneshvar, Mehdi Mollapour

15292-15298
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Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis

http://dx.doi.org/10.18632/oncotarget.8191
Maria L. Mancini, Evan C. Lien and Alex Toker

17301-17313
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Age related increase in mTOR activity contributes to the pathological changes in ovarian surface epithelium

http://dx.doi.org/10.18632/oncotarget.8468
Preety Bajwa, Prathima B. Nagendra, Sarah Nielsen, Subhransu S. Sahoo, Amanda Bielanowicz, Janine M. Lombard, J. Erby Wilkinson, Richard A. Miller and Pradeep S. Tanwar

19214-19227
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A monoclonal antibody against the Wnt signaling inhibitor dickkopf-1 inhibits osteosarcoma metastasis in a preclinical model

http://dx.doi.org/10.18632/oncotarget.8522
Seth D. Goldstein, Matteo Trucco, Wendy Bautista Guzman, Masanori Hayashi and David M. Loeb

21114-21123
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Addiction to Runx1 is partially attenuated by loss of p53 in the Eμ-Myc lymphoma model

http://dx.doi.org/10.18632/oncotarget.8554
Gillian Borland, Anna Kilbey, Jodie Hay, Kathryn Gilroy, Anne Terry, Nancy Mackay, Margaret Bell, Alma McDonald, Ken Mills, Ewan Cameron and James C. Neil

22973-22987
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Differential localization of glioblastoma subtype: implications on glioblastoma pathogenesis

http://dx.doi.org/10.18632/oncotarget.8551
Tyler C. Steed, Jeffrey M. Treiber, Kunal Patel, Valya Ramakrishnan, Alexander Merk, Amanda R. Smith, Bob S. Carter, Anders M. Dale, Lionel M. L. Chow and Clark C. Chen

24899-24907
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BIM mediates oncogene inactivation-induced apoptosis in multiple transgenic mouse models of acute lymphoblastic leukemia

http://dx.doi.org/10.18632/oncotarget.8731
Yulin Li, Anja Deutzmann, Peter S. Choi, Alice C. Fan and Dean W. Felsher

26926-26934
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Angiomotin stabilization by tankyrase inhibitors antagonizes constitutive TEAD-dependent transcription and proliferation of human tumor cells with Hippo pathway core component mutations

http://dx.doi.org/10.18632/oncotarget.9117
Albino Troilo, Erica K. Benson, Davide Esposito, Rachel-Ann A. Garibsingh, E. Premkumar Reddy, Sathish Kumar Mungamuri and Stuart A. Aaronson

28765-28782
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Dual B- and T-cell de-immunization of recombinant immunotoxin targeting mesothelin with high cytotoxic activity

http://dx.doi.org/10.18632/oncotarget.9171
Ronit Mazor, Masanori Onda, Dong Park, Selamawit Addissie, Laiman Xiang, Jingli Zhang, Raffit Hassan and Ira Pastan

29916-29926
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The impact of the MYB-NFIB fusion proto-oncogene in vivo

http://dx.doi.org/10.18632/oncotarget.9426
Oliver R. Mikse, Jeremy H. Tchaicha, Esra A. Akbay, Liang Chen, Roderick T. Bronson, Peter S. Hammerman, and Kwok-Kin Wong

31681-31688
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Metabolic reprogramming of glioblastoma cells by L-asparaginase sensitizes for apoptosis in vitro and in vivo

http://dx.doi.org/10.18632/oncotarget.9257
Georg Karpel-Massler, Doruntina Ramani, Chang Shu, Marc-Eric Halatsch, Mike-Andrew Westhoff, Jeffrey N. Bruce, Peter Canoll and Markus D. Siegelin

33512-33528
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Tumor acidosis enhances cytotoxic effects and autophagy inhibition by salinomycin on cancer cell lines and cancer stem cells

http://dx.doi.org/10.18632/oncotarget.9601
Paola Pellegrini, Matheus Dyczynski, Francesca Vittoria Sbrana, Maria Karlgren, Maria Buoncervello, Maria Hägg-Olofsson, Ran Ma, Johan Hartman, Svetlana Bajalica-Lagercrantz, Dan Grander, Pedram Kharaziha and Angelo De Milito

35703-35723
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Intrinsic resistance to PIM kinase inhibition in AML through p38α-mediated feedback activation of mTOR signaling

http://dx.doi.org/10.18632/oncotarget.9822
Diede Brunen, María José García-Barchino, Disha Malani, Noorjahan Jagalur Basheer, Cor Lieftink, Roderick L. Beijersbergen, Astrid Murumägi, Kimmo Porkka, Maija Wolf, C. Michel Zwaan, Maarten Fornerod, Olli Kallioniemi, José Ángel Martínez-Climent and René Bernards

37407-37419
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MUC1-C induces DNA methyltransferase 1 and represses tumor suppressor genes in acute myeloid leukemia

http://dx.doi.org/10.18632/oncotarget.9777
Ashujit Tagde, Hasan Rajabi, Dina Stroopinsky, Reddy Gali, Maroof Alam, Audrey Bouillez, Surender Kharbanda, Richard Stone, David Avigan and Donald Kufe

38974-38987
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Osteoprotegerin rich tumor microenvironment: implications in breast cancer

http://dx.doi.org/10.18632/oncotarget.8658
Sudeshna Goswami and Neelam Sharma-Walia

42777-42791
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Definitive activation of endogenous antitumor immunity by repetitive cycles of cyclophosphamide with interspersed Toll-like receptor agonists

http://dx.doi.org/10.18632/oncotarget.10190
Soraya Zorro Manrique, Ana L. Dominguez, Noweeda Mirza, Christopher D. Spencer, Judy M. Bradley, James H. Finke, James J. Lee, Larry R. Pease, Sandra J. Gendler, and Peter A. Cohen

42919-42942
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Parp1 protects against Aag-dependent alkylation-induced nephrotoxicity in a sex-dependent manner

http://dx.doi.org/10.18632/oncotarget.10440
Jennifer A. Calvo, Mariacarmela Allocca, Kimberly R. Fake, Sureshkumar Muthupalani, Joshua J. Corrigan, Roderick T. Bronson and Leona D. Samson

44950-44965
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Deletion of 14-3-3σ sensitizes mice to DMBA/TPA-induced papillomatosis

http://dx.doi.org/10.18632/oncotarget.10478
Markus Winter, Dmitri Lodygin, Berlinda Verdoodt and Heiko Hermeking

46862-46870
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PIP3-binding proteins promote age-dependent protein aggregation and limit survival in C. elegans

http://dx.doi.org/10.18632/oncotarget.10549
Srinivas Ayyadevara, Meenakshisundaram Balasubramaniam, Jay Johnson, Ramani Alla, Samuel G. Mackintosh and Robert J. Shmookler Reis

48870-48886
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Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma

http://dx.doi.org/10.18632/oncotarget.9682
Breanna M. Javier, Rona Yaeger, Lu Wang, Francisco Sanchez-Vega, Ahmet Zehir, Sumit Middha, Justyna Sadowska, Efsevia Vakiani, Jinru Shia, David Klimstra, Marc Ladanyi, Christine A. Iacobuzio-Donahue, and Jaclyn F. Hechtman

50875-50882
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β1 integrin- and JNK-dependent tumor growth upon hypofractionated radiation

http://dx.doi.org/10.18632/oncotarget.10522
Aejaz Sayeed, Huimin Lu, Qin Liu, David Deming II, Alexander Duffy, Peter McCue, Adam P. Dicker, Roger J. Davis, Dmitry Gabrilovich, Ulrich Rodeck, Dario C. Altieri, and Lucia R. Languino

52618-52630
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CNS germinomas are characterized by global demethylation, chromosomal instability and mutational activation of the Kit-, Ras/Raf/Erk- and Akt-pathways

http://dx.doi.org/10.18632/oncotarget.10392
Simone Laura Schulte, Andreas Waha, Barbara Steiger, Dorota Denkhaus, Evelyn Dörner, Gabriele Calaminus, Ivo Leuschner, Torsten Pietsch

55026-55042
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BMP9/ALK1 inhibits neovascularization in mouse models of age-related macular degeneration

http://dx.doi.org/10.18632/oncotarget.11182
Kalonji Ntumba, Naoufal Akla, S. Paul Oh, Anne Eichmann and Bruno Larrivée

55957-55969
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Inhibition of mTOR-kinase destabilizes MYCN and is a potential therapy for MYCN-dependent tumors

http://dx.doi.org/10.18632/oncotarget.10544
Lynsey Vaughan, Paul A. Clarke, Karen Barker, Yvan Chanthery, Clay W. Gustafson, Elizabeth Tucker, Jane Renshaw, Florence Raynaud, Xiaodun Li, Rosemary Burke, Yann Jamin, Simon P. Robinson, Andrew Pearson, Michel Maira, William A. Weiss, Paul Workman and Louis Chesler

57525-57544
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PDCD4 is a CSL associated protein with a transcription repressive function in cancer associated fibroblast activation

http://dx.doi.org/10.18632/oncotarget.11227
Seung-Hee Jo, Dong Eun Kim, Andrea Clocchiatti, and G. Paolo Dotto

58717-58727
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Llgl1 prevents metaplastic survival driven by epidermal growth factor dependent migration

http://dx.doi.org/10.18632/oncotarget.11320
Erin Greenwood, Sabrina Maisel, David Ebertz, Atlantis Russ, Ritu Pandey, and Joyce Schroeder

60776-60792
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γ-secretase inhibitor I inhibits neuroblastoma cells, with NOTCH and the proteasome among its targets

http://dx.doi.org/10.18632/oncotarget.11715
Carmen Dorneburg, Annika V. Goß, Matthias Fischer, Frederik Roels, Thomas F.E. Barth, Frank Berthold, Roland Kappler, Franz Oswald, Jens T. Siveke, Jan J. Molenaar, Klaus-Michael Debatin, and Christian Beltinger

62799-62813
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Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells

http://dx.doi.org/10.18632/oncotarget.11743
Chuanzhao Zhang, Wanqing Iris Zhi, Haiquan Lu, Debangshu Samanta, Ivan Chen, Edward Gabrielson, and Gregg L. Semenza

64527-64542
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MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma

http://dx.doi.org/10.18632/oncotarget.11662
Johannes Fabian, Desirée Opitz, Kristina Althoff, Marco Lodrini, Barbara Hero, Ruth Volland, Anneleen Beckers, Katleen de Preter, Anneleen Decock, Nitin Patil, Mohammed Abba, Annette Kopp-Schneider, Kathy Astrahantseff, Jasmin Wünschel, Sebastian Pfeil, Maria Ercu, Annette Künkele, Jamie Hu, Theresa Thole, Leonille Schweizer, Gunhild Mechtersheimer, Daniel Carter, Belamy B. Cheung, Odilia Popanda, Andreas von Deimling, Jan Koster, Rogier Versteeg, Manfred Schwab, Glenn M. Marshall, Frank Speleman, Ulrike Erb, Margot Zoeller, Heike Allgayer, Thorsten Simon, Matthias Fischer, Andreas E. Kulozik, Angelika Eggert, Olaf Witt, Johannes H. Schulte and Hedwig E. Deubzer

66344-66359
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Role of TP53 mutations in triple negative and HER2-positive breast cancer treated with neoadjuvant anthracycline/taxane-based chemotherapy

http://dx.doi.org/10.18632/oncotarget.11891
Silvia Darb-Esfahani, Carsten Denkert, Albrecht Stenzinger, Christoph Salat, Bruno Sinn, Christian Schem, Volker Endris, Peter Klare, Wolfgang Schmitt, Jens-Uwe Blohmer, Wilko Weichert, Markus Möbs, Hans Tesch, Sherko Kümmel, Peter Sinn, Christian Jackisch, Manfred Dietel, Toralf Reimer, Sherene Loi, Michael Untch, Gunter von Minckwitz, Valentina Nekljudova and Sibylle Loibl

67686-67698
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Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer

http://dx.doi.org/10.18632/oncotarget.10215
Shalaka S. Hampras, Lara E. Sucheston-Campbell, Rikki Cannioto, Jenny Chang-Claude, Francesmary Modugno, Thilo Dörk, Peter Hillemanns, Leah Preus, Keith L. Knutson, Paul K.Wallace, Chi-Chen Hong, Grace Friel, Warren Davis, Mary Nesline, Celeste L. Pearce, Linda E. Kelemen, Marc T. Goodman, Elisa V. Bandera, Kathryn L. Terry, Nils Schoof, Kevin H. Eng, Alyssa Clay, Prashant K. Singh, Janine M. Joseph, Katja K.H. Aben, Hoda Anton-Culver, Natalia Antonenkova, Helen Baker, Yukie Bean, Matthias W. Beckmann, Maria Bisogna, Line Bjorge, Natalia Bogdanova, Louise A. Brinton, Angela Brooks-Wilson, Fiona Bruinsma, Ralf Butzow, Ian G. Campbell, Karen Carty, Linda S. Cook, Daniel W. Cramer, Cezary Cybulski, Agnieszka Dansonka-Mieszkowska, Joe Dennis, Evelyn Despierre, Ed Dicks, Jennifer A. Doherty, Andreas du Bois, Matthias Dürst, Doug Easton, Diana Eccles, Robert P. Edwards, Arif B. Ekici, Peter A. Fasching, Brooke L. Fridley, Yu-Tang Gao, Aleksandra Gentry-Maharaj, Graham G. Giles, Rosalind Glasspool, Jacek Gronwald, Patricia Harrington, Philipp Harter, Hanis Nazihah Hasmad, Alexander Hein, Florian Heitz, Michelle A.T. Hildebrandt, Claus Hogdall, Estrid Hogdall, Satoyo Hosono, Edwin S. Iversen, Anna Jakubowska, Allan Jensen, Bu-Tian Ji, Beth Y. Karlan, Melissa Kellar, Joseph L. Kelley, Lambertus A. Kiemeney, Rüdiger Klapdor, Nonna Kolomeyevskaya, Camilla Krakstad, Susanne K. Kjaer, Bridget Kruszka, Jolanta Kupryjanczyk, Diether Lambrechts, Sandrina Lambrechts, Nhu D. Le, Alice W. Lee, Shashikant Lele, Arto Leminen, Jenny Lester, Douglas A. Levine, Dong Liang, Jolanta Lissowska, Song Liu, Karen Lu, Jan Lubinski, Lene Lundvall, Leon F.A.G. Massuger, Keitaro Matsuo, Valeria McGuire, John R. McLaughlin, Ian McNeish, Usha Menon, Joanna Moes-Sosnowska, Steven A. Narod, Lotte Nedergaard, Heli Nevanlinna, Stefan Nickels, Sara H. Olson, Irene Orlow, Rachel Palmieri Weber, James Paul, Tanja Pejovic, Liisa M. Pelttari, Barbara Perkins, Jenny Permuth-Wey, Malcolm C. Pike, Joanna Plisiecka-Halasa, Elizabeth M. Poole, Harvey A. Risch, Mary Anne Rossing, Joseph H. Rothstein, Anja Rudolph, Ingo B. Runnebaum, Iwona K. Rzepecka, Helga B. Salvesen, Eva Schernhammer, Kristina Schmitt, Ira Schwaab, Xiao-Ou Shu, Yurii B Shvetsov, Nadeem Siddiqui, Weiva Sieh, Honglin Song, Melissa C. Southey, Ingvild L. Tangen, Soo-Hwang Teo, Pamela J. Thompson, Agnieszka Timorek, Ya-Yu Tsai, Shelley S. Tworoger, Jonathan Tyrer, Anna M. van Altena, Ignace Vergote, Robert A. Vierkant, Christine Walsh, Shan Wang-Gohrke, Nicolas Wentzensen, Alice S. Whittemore, Kristine G. Wicklund, Lynne R. Wilkens, Anna H. Wu, Xifeng Wu, Yin-Ling Woo, Hannah Yang, Wei Zheng, Argyrios Ziogas, Simon A. Gayther, Susan J. Ramus, Thomas A. Sellers, Joellen M. Schildkraut, Catherine M. Phelan, Andrew Berchuck, Georgia Chenevix-Trench, Julie M. Cunningham, Paul P. Pharoah, Roberta B. Ness, Kunle Odunsi, Ellen L. Goode and Kirsten B. Moysich

69097-69110
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Assessing angiogenic responses induced by primary human prostate stromal cells in a three-dimensional fibrin matrix assay

http://dx.doi.org/10.18632/oncotarget.11347
W. Nathaniel Brennen, Huong Nguyen, Susan L. Dalrymple, Stephanie Reppert-Gerber, Jeesun Kim, John T. Isaacs, Hans Hammers

71298-71308
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Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a large-scale collaboration

http://dx.doi.org/10.18632/oncotarget.10546
Jennifer B. Permuth, Brett Reid, Madalene Earp, Y. Ann Chen, Alvaro N.A. Monteiro, Zhihua Chen, AOCS Study Group, Georgia Chenevix-Trench, Peter A. Fasching, Matthias W. Beckmann, Diether Lambrechts, Adriaan Vanderstichele, Els Van Niewenhuyse, Ignace Vergote, Mary Anne Rossing, Jennifer Anne Doherty, Jenny Chang-Claude, Kirsten Moysich, Kunle Odunsi, Marc T. Goodman, Yurii B. Shvetsov, Lynne R. Wilkens, Pamela J. Thompson, Thilo Dörk, Natalia Bogdanova, Ralf Butzow, Heli Nevanlinna, Liisa Pelttari, Arto Leminen, Francesmary Modugno, Robert P. Edwards, Roberta B. Ness, Joseph Kelley, Florian Heitz, Beth Karlan, Jenny Lester, Susanne K. Kjaer, Allan Jensen, Graham Giles, Michelle Hildebrandt, Dong Liang, Karen H. Lu, Xifeng Wu, Douglas A. Levine, Maria Bisogna, Andrew Berchuck, Daniel W. Cramer, Kathryn L. Terry, Shelley S. Tworoger, Elizabeth M. Poole, Elisa V. Bandera, Brooke Fridley, Julie Cunningham, Stacey J. Winham, Sara H. Olson, Irene Orlow, Line Bjorge, Lambertus A. Kiemeney, Leon Massuger, Tanja Pejovic, Melissa Moffitt, Nhu Le, Linda S. Cook, Angela Brooks-Wilson, Linda E. Kelemen, Jacek Gronwald, Jan Lubinski, Nicolas Wentzensen, Louise A. Brinton, Jolanta Lissowska, Hanna Yang, Estrid Hogdall, Claus Hogdall, Lene Lundvall, Paul D.P. Pharoah, Honglin Song, Ian Campbell, Diana Eccles, Iain McNeish, Alice Whittemore, Valerie McGuire, Weiva Sieh, Joseph Rothstein, Catherine M. Phelan, Harvey Risch, Steven Narod, John McLaughlin, Hoda Anton-Culver, Argyrios Ziogas, Usha Menon, Simon Gayther, Susan J. Ramus, Aleksandra Gentry-Maharaj, Celeste Leigh Pearce, Anna H. Wu, Jolanta Kupryjanczyk, Agnieszka Dansonka-Mieszkowska, Joellen M. Schildkraut, Jin Q. Cheng, Ellen L. Goode and Thomas A. Sellers

72381-72394
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Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cells

http://dx.doi.org/10.18632/oncotarget.12766
Kathrin Fielitz, Kristina Althoff, Katleen De Preter, Julie Nonnekens, Jasmin Ohli, Sandra Elges, Wolfgang Hartmann, Günter Klöppel, Thomas Knösel, Marc Schulte, Ludger Klein-Hitpass, Daniela Beisser, Henning Reis, Annette Eyking, Elke Cario, Johannes H. Schulte, Alexander Schramm and Ulrich Schüller

74415-74426
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Genomic profiling is predictive of response to cisplatin treatment but not to PI3K inhibition in bladder cancer patient-derived xenografts

http://dx.doi.org/10.18632/oncotarget.13062
Lei Wei, Sreenivasulu Chintala, Eric Ciamporcero, Swathi Ramakrishnan, May Elbanna, Jianmin Wang, Qiang Hu, Sean T. Glenn, Mitsuko Murakami, Lu Liu, Eduardo Cortes Gomez, Yuchen Sun, Jacob Conroy, Kiersten Marie Miles, Kullappan Malathi, Sudha Ramaiah, Anand Anbarasu, Anna Woloszynska-Read, Candace S. Johnson, Jeffrey Conroy, Song Liu, Carl D. Morrison and Roberto Pili

76374-76389
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A randomized phase II trial comparing chemoimmunotherapy with or without bevacizumab in previously untreated patients with chronic lymphocytic leukemia

http://dx.doi.org/10.18632/oncotarget.13412
Neil E. Kay, Paolo Strati, Betsy R. LaPlant, Jose F. Leis, Daniel Nikcevich, Timothy G. Call, Adam M. Pettinger, Connie E. Lesnick, Curtis A. Hanson and Tait D. Shanafelt

78269-78280
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Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21

http://dx.doi.org/10.18632/oncotarget.12818
Yosr Hamdi, Penny Soucy, Véronique Adoue, Kyriaki Michailidou, Sander Canisius, Audrey Lemaçon, Arnaud Droit, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Caroline Baynes, Carl Blomqvist, Natalia V. Bogdanova, Stig E. Bojesen, Manjeet K. Bolla, Bernardo Bonanni, Anne-Lise Borresen-Dale, Judith S. Brand, Hiltrud Brauch, Hermann Brenner, Annegien Broeks, Barbara Burwinkel, Jenny Chang-Claude, NBCS Collaborators, Fergus J. Couch, Angela Cox, Simon S. Cross, Kamila Czene, Hatef Darabi, Joe Dennis, Peter Devilee, Thilo Dörk, Isabel Dos-Santos-Silva, Mikael Eriksson, Peter A. Fasching, Jonine Figueroa, Henrik Flyger, Montserrat García-Closas, Graham G. Giles, Mark S. Goldberg, Anna González-Neira, Grethe Grenaker-Alnæs, Pascal Guénel, Lothar Haeberle, Christopher A. Haiman, Ute Hamann, Emily Hallberg, Maartje J. Hooning, John L. Hopper, Anna Jakubowska, Michael Jones, Maria Kabisch, Vesa Kataja, Diether Lambrechts, Loic Le Marchand, Annika Lindblom, Jan Lubinski, Arto Mannermaa, Mel Maranian, Sara Margolin, Frederik Marme, Roger L. Milne, Susan L. Neuhausen, Heli Nevanlinna, Patrick Neven, Curtis Olswold, Julian Peto, Dijana Plaseska-Karanfilska, Katri Pylkäs, Paolo Radice, Anja Rudolph, Elinor J. Sawyer, Marjanka K. Schmidt, Xiao-Ou Shu, Melissa C. Southey, Anthony Swerdlow, Rob A.E.M. Tollenaar, Ian Tomlinson, Diana Torres, Thérèse Truong, Celine Vachon, Ans M. W. Van Den Ouweland, Qin Wang, Robert Winqvist, kConFab/AOCS Investigators, Wei Zheng, Javier Benitez, Georgia Chenevix-Trench, Alison M. Dunning, Paul D. P. Pharoah, Vessela Kristensen, Per Hall, Douglas F. Easton, Tomi Pastinen, Silje Nord and Jacques Simard

80140-80163
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LINC00520 is induced by Src, STAT3, and PI3K and plays a functional role in breast cancer

http://dx.doi.org/10.18632/oncotarget.11962
Whitney S. Henry, David G. Hendrickson, Francisco Beca, Benjamin Glass, Marianne Lindahl-Allen, Lizhi He, Zhe Ji, Kevin Struhl, Andrew H. Beck, John L. Rinn, and Alex Toker

81981-81994
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Ceramide activates lysosomal cathepsin B and cathepsin D to attenuate autophagy and induces ER stress to suppress myeloid-derived suppressor cells

http://dx.doi.org/10.18632/oncotarget.13438
Feiyan Liu, Xia Li, Chunwan Lu, Aiping Bai, Jacek Bielawski, Alicja Bielawska, Brendan Marshall, Patricia V. Schoenlein, Iryna O. Lebedyeva and Kebin Liu

83907-83925
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Germ cell-specific sustained activation of Wnt signalling perturbs spermatogenesis in aged mice, possibly through non-coding RNAs

http://dx.doi.org/10.18632/oncotarget.13920
Manish Kumar, Joshua Atkins, Murray Cairns, Ayesha Ali and Pradeep S. Tanwar

85709-85727
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