About The Cover
Representative images of immunohistochemical staining for Extracellular Sulfatase Sulf-2 (SULF2) in pediatric Glioblastoma (GBM). See Phillips et al.
Table of Contents
Editorial Comments
| Targeting Protein-Tyrosine Phosphatases in Breast Cancer |
| Nicola Aceto, and Mohamed Bentires-Alj |
| 514-515 |
| PDF Full Text |
| Voltage-dependent K+ channels as oncotargets in malignant gliomas |
| Florence Lefranc, Henri-Benjamin Pouleau, Michal Rynkowski, and Olivier De Witte |
| 516-517 |
| PDF Full Text |
Brief Reports
| A novel co-operative mechanism linking TGFβ and Lyn kinase activation to imatinib resistance in chronic myeloid leukaemia cells |
| Andrew Chantry, Paul G Smith, and Hideo Tanaka |
| 518-524 |
| Abstract PDF Full Text |
Research Papers
| The Hsp90 inhibitor NVP-AUY922-AG inhibits NF-κB signaling, overcomes microenvironmental cytoprotection and is highly synergistic with fludarabine in primary CLL cells |
| Elisabeth J. Walsby, Laurence Pearce, Alan K. Burnett, Chris Fegan, and Chris Pepper |
| 525-534 |
| Abstract PDF Full Text |
| A chemical screen identifies the chemotherapeutic drug topotecan as a specific inhibitor of the B-MYB/MYCN axis in neuroblastoma. |
| Francesco Sottile, Ilaria Gnemmi, Sandra Cantilena, Walter C. D'Acunto, and Arturo Sala |
| 535-545 |
| Abstract PDF Full Text Supplementary Files |
| Dramatic reduction of sequence artefacts from DNA isolated from formalin-fixed cancer biopsies by treatment with uracil-DNA glycosylase. |
| Hongdo Do, and Alexander Dobrovic |
| 546-558 |
| Abstract PDF Full Text |
Research Perspectives
| Solid Tumor Differentiation Therapy – Is It Possible? |
| Filemon Dela cruz, and Igor Matushansky |
| 559-567 |
| Abstract PDF Full Text |
| Novel Therapeutic Targets in the Brain Tumor Microenvironment |
| Joanna J. Phillips |
| 568-575 |
| Abstract PDF Full Text |
| FLT3 in lineage specification and plasticity |
| Sarah Greenblatt, and Donald Small |
| 576-580 |
| Abstract PDF Full Text |
| Cell-based high-throughput screens for the discovery of chemotherapeutic agents |
| Jennifer T Fox, and Kyungiae Myung |
| 581-585 |
| Abstract PDF Full Text |
Methodological Reports
| Mantle cell lymphoma-like lymphomas in c-myc-3’RR/p53+/- mice and c-myc-3’RR/Cdk4R24C mice: differential oncogenic mechanisms but similar cellular origin |
| Pauline Rouaud, Rémi Fiancette, Christelle Vincent-Fabert, Virginie Magnone, Michel Cogné, Pierre Dubus, and Yves Denizot |
| 586-593 |
| Abstract PDF Full Text |
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