Oncotarget

Vol 5, No 23

December 15, 2014

View Archive »

Order a Reprint

About The Cover

ED-A is expressed both in primary tumors and metastases in the MMTV-PyMT model of mammary carcinoma. See Femel et al.

Table of Contents

Reviews

BRAF vs RAS oncogenes: Are mutations of the same pathway equal? Differential signalling and therapeutic implications

BRAF vs RAS oncogenes: Are mutations of the same pathway equal? Differential signalling and therapeutic implications

https://doi.org/10.18632/oncotarget.2555

Eftychia Oikonomou, Evangelos Koustas, Maria Goulielmaki,  and Alexander Pintzas
11752-11777
Abstract  |  PDF  |  HTML  |  Order a Reprint

Priority Research Papers

Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation

Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation

https://doi.org/10.18632/oncotarget.2634

Ulrike Keitel, Andreas Scheel, Jürgen Thomale, Rovena Halpape, Silke Kaulfuß, Christina Scheel,  and Matthias Dobbelstein
11778-11791
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reviews: Gerotarget (Focus on Aging)

WW domain-containing oxidoreductase in neuronal injury and neurological diseases

WW domain-containing oxidoreductase in neuronal injury and neurological diseases

https://doi.org/10.18632/oncotarget.2961

Hsin-Tzu Chang, Chan-Chuan Liu, Shur-Tzu Chen, Ye Vone Yap, Nan-Shang Chang,  and Chun-I Sze
11792-11799
Abstract  |  PDF  |  HTML  |  Order a Reprint

Research Papers: Gerotarget (Focus on Aging)

ROS production, intracellular HSP70 levels and their relationship in human neutrophils: effects of age

ROS production, intracellular HSP70 levels and their relationship in human neutrophils: effects of age

https://doi.org/10.18632/oncotarget.2856

Elena I. Kovalenko, Anna A. Boyko, Victor F. Semenkov, Gennady V. Lutsenko, Maria V. Grechikhina, Leonid M. Kanevskiy, Tatyana L. Azhikina, William G. Telford,  and Alexander M. Sapozhnikov
11800-11812
Abstract  |  PDF  |  HTML  |  Order a Reprint

A microRNA signature profile in EBV+ diffuse large B-cell lymphoma of the elderly

A microRNA signature profile in EBV+ diffuse large B-cell lymphoma of the elderly

https://doi.org/10.18632/oncotarget.2952

Tathiana Azevedo de Andrade, Adriane Feijo Evangelista, Antonio Hugo Froes Campos, Wagner Augusto Poles, Natalia Morais Borges, Claudia Malheiros Coutinho Camillo, Fernando Augusto Soares, Jose Vassallo, Roberto Pinto Paes, Maria Claudia Zerbini, Cristovam Scapulatempo, Antonio Correa Alves, Ken H. Young,  and Gisele Wally Braga Colleoni
11813-11826
Abstract  |  PDF  |  HTML  |  Order a Reprint

Research Papers

Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and growth inhibition of breast cancer cells and cancer stem-like cells

Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and growth inhibition of breast cancer cells and cancer stem-like cells

https://doi.org/10.18632/oncotarget.2582

Itay Pickholtz, Shira Saadyan, Gilmor I. Keshet, Victor S. Wang, Rachel Cohen, Peter Bouwman, Jos Jonkers, Stephen W. Byers, Moshe Z. Papa,  and Ronit I. Yarden
11827-11846
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells

The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells

https://doi.org/10.18632/oncotarget.2663

Hisato Kawakami, Isamu Okamoto, Kimio Yonesaka, Kunio Okamoto, Kiyoko Shibata, Yume Shinkai, Haruka Sakamoto, Michiko Kitano, Takao Tamura, Kazuto Nishio,  and Kazuhiko Nakagawa
11847-11856
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Phospholipase D1 protein coordinates dynamic assembly of HIF-1α-PHD-VHL to regulate HIF-1α stability

Phospholipase D1 protein coordinates dynamic assembly of HIF-1α-PHD-VHL to regulate HIF-1α stability

https://doi.org/10.18632/oncotarget.2613

Mi Hee Park, Kang-Yell Choi, Yunjin Jung,  and Do Sik Min
11857-11872
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reduced miR-126 expression facilitates angiogenesis of gastric cancer through its regulation on VEGF-A

Reduced miR-126 expression facilitates angiogenesis of gastric cancer through its regulation on VEGF-A

https://doi.org/10.18632/oncotarget.2662

Hongxia Chen, Lingmin Li, Shaojun Wang, Yupeng Lei, Qi Ge, Nonghua Lv, Xiaodong Zhou,  and Changyan Chen
11873-11885
Abstract  |  PDF  |  HTML  |  Order a Reprint

Different effects of LDH-A inhibition by oxamate in non-small cell lung cancer cells

Different effects of LDH-A inhibition by oxamate in non-small cell lung cancer cells

https://doi.org/10.18632/oncotarget.2620

Yang Yang, Dan Su, Lin Zhao, Dan Zhang, Jiaying Xu, Jianmei Wan, Saijun Fan,  and Ming Chen
11886-11896
Abstract  |  PDF  |  HTML  |  Order a Reprint

Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells

Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells

https://doi.org/10.18632/oncotarget.2472

Giulia Guzzo, Marco Sciacovelli, Paolo Bernardi,  and Andrea Rasola
11897-11908
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ret finger protein-like 3 promotes tumor cell growth by activating telomerase reverse transcriptase expression in human lung cancer cells

Ret finger protein-like 3 promotes tumor cell growth by activating telomerase reverse transcriptase expression in human lung cancer cells

https://doi.org/10.18632/oncotarget.2557

Wangbing Chen, Jianjun Lu, Yu Qin, Jingshu Wang, Yun Tian, Dingbo Shi, Shusen Wang, Yao Xiao, Meng Dai, Lu Liu, Guo Wei, Taihua Wu, Bilian Jin, Xiangsheng Xiao, Tie-Bang Kang, Wenlin Huang,  and Wuguo Deng
11909-11923
Abstract  |  PDF  |  HTML  |  Order a Reprint

Genetic prevention of lymphoma in p53 knockout mice allows the early development of p53-related sarcomas

Genetic prevention of lymphoma in p53 knockout mice allows the early development of p53-related sarcomas

https://doi.org/10.18632/oncotarget.2650

Lorena Landuzzi, Marianna L. Ianzano, Giordano Nicoletti, Arianna Palladini, Valentina Grosso, Dario Ranieri, Massimiliano Dall’Ora, Elena Raschi, Roberta Laranga, Marco Gambarotti, Piero Picci, Carla De Giovanni, Patrizia Nanni,  and Pier-Luigi Lollini
11924-11938
Abstract  |  PDF  |  HTML  |  Order a Reprint

Transcriptomic profiling of taxol-resistant ovarian cancer cells identifies FKBP5 and the androgen receptor as critical markers of chemotherapeutic response

Transcriptomic profiling of taxol-resistant ovarian cancer cells identifies FKBP5 and the androgen receptor as critical markers of chemotherapeutic response

https://doi.org/10.18632/oncotarget.2654

Nian-Kang Sun, Shang-Lang Huang, Pu-Yuan Chang, Hsing-Pang Lu,  and Chuck C.-K. Chao
11939-11956
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MBL-II-141, a chromone derivative, enhances irinotecan (CPT-11) anticancer efficiency in ABCG2-positive xenografts

MBL-II-141, a chromone derivative, enhances irinotecan (CPT-11) anticancer efficiency in ABCG2-positive xenografts

https://doi.org/10.18632/oncotarget.2566

Mylène Honorat, Jérôme Guitton, Charlotte Gauthier, Charlotte Bouard, Florine Lecerf-Schmidt, Basile Peres, Raphaël Terreux, Héloïse Gervot, Catherine Rioufol, Ahcène Boumendjel, Alain Puisieux, Attilio Di Pietro,  and Léa Payen
11957-11970
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Afatinib circumvents multidrug resistance via dually inhibiting ATP binding cassette subfamily G member 2 in vitro and in vivo

Afatinib circumvents multidrug resistance via dually inhibiting ATP binding cassette subfamily G member 2 in vitro and in vivo

https://doi.org/10.18632/oncotarget.2647

Xiao-kun Wang, Kenneth Kin Wah To, Li-yan Huang, Jing-hong Xu, Ke Yang, Fang Wang, Zhen-cong Huang, Sheng Ye,  and Li-wu Fu
11971-11985
Abstract  |  PDF  |  HTML  |  Order a Reprint

NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma

NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma

https://doi.org/10.18632/oncotarget.2388

Ye Yang, Wen Zhou, Jiliang Xia, Zhimin Gu, Erik Wendlandt, Xin Zhan, Siegfried Janz, Guido Tricot,  and Fenghuang Zhan
11986-11997
Abstract  |  PDF  |  HTML  |  Order a Reprint

The orthologous Tbx transcription factors Omb and TBX2 induce epithelial cell migration and extrusion in vivo without involvement of matrix metalloproteinases

The orthologous Tbx transcription factors Omb and TBX2 induce epithelial cell migration and extrusion in vivo without involvement of matrix metalloproteinases

https://doi.org/10.18632/oncotarget.2426

Jie Shen, Juan Lu, Liyuan Sui, Dan Wang, Meizhen Yin, Inka Hoffmann, Anne Legler,  and Gert O. Pflugfelder
11998-12015
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Role of p53 in the progression of gastric cancer

Role of p53 in the progression of gastric cancer

https://doi.org/10.18632/oncotarget.2434

Rita A. Busuttil, Giada V. Zapparoli, Sue Haupt, Christina Fennell, Stephen Q. Wong, Jia-Min B. Pang, Elena A. Takeno, Catherine Mitchell, Natasha Di Costanzo, Stephen Fox, Ygal Haupt, Alexander Dobrovic,  and Alex Boussioutas
12016-12026
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Melanoma-initiating cells exploit M2 macrophage TGFβ and arginase pathway for survival and proliferation

Melanoma-initiating cells exploit M2 macrophage TGFβ and arginase pathway for survival and proliferation

https://doi.org/10.18632/oncotarget.2482

Muly Tham, Kar Wai Tan, Jo Keeble, Xiaojie Wang, Sandra Hubert, Luke Barron, Nguan Soon Tan, Masashi Kato, Armelle Prevost-Blondel, Veronique Angeli,  and Jean-Pierre Abastado
12027-12042
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PIAS1 is a crucial factor for prostate cancer cell survival and a valid target in docetaxel resistant cells

PIAS1 is a crucial factor for prostate cancer cell survival and a valid target in docetaxel resistant cells

https://doi.org/10.18632/oncotarget.2658

Martin Puhr, Julia Hoefer, Hannes Neuwirt, Iris E. Eder, Johann Kern, Georg Schäfer, Stephan Geley, Isabel Heidegger, Helmut Klocker,  and Zoran Culig
12043-12056
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

AGK enhances angiogenesis and inhibits apoptosis via activation of the NF-κB signaling pathway in hepatocellular carcinoma

AGK enhances angiogenesis and inhibits apoptosis via activation of the NF-κB signaling pathway in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.2666

Yanmei Cui, Chuyong Lin, Zhiqiang Wu, Aibin Liu, Xin Zhang, Jinrong Zhu, Geyan Wu, Jueheng Wu, Mengfeng Li, Jun Li,  and Libing Song
12057-12069
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Acidosis promotes invasiveness of breast cancer cells through ROS-AKT-NF-κB pathway

Acidosis promotes invasiveness of breast cancer cells through ROS-AKT-NF-κB pathway

https://doi.org/10.18632/oncotarget.2514

Subash C. Gupta, Ramesh Singh, Radhika Pochampally, Kounosuke Watabe,  and Yin-Yuan Mo
12070-12082
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-638 inhibits cell proliferation, invasion and regulates cell cycle by targeting tetraspanin 1 in human colorectal carcinoma

MicroRNA-638 inhibits cell proliferation, invasion and regulates cell cycle by targeting tetraspanin 1 in human colorectal carcinoma

https://doi.org/10.18632/oncotarget.2499

Jiwei Zhang, Bojian Fei, Qifeng Wang, Mingxu Song, Yuan Yin, Binbin Zhang, Shujuan Ni, Weijie Guo, Zehua Bian, Chao Quan, Zhihui Liu, Yugang Wang, Jian Yu, Xiang Du, Dong Hua,  and Zhaohui Huang
12083-12096
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

E-selectin ligand-1 controls circulating prostate cancer cell rolling/adhesion and metastasis

E-selectin ligand-1 controls circulating prostate cancer cell rolling/adhesion and metastasis

https://doi.org/10.18632/oncotarget.2503

Sayeda Yasmin-Karim, Michael R. King, Edward M. Messing,  and Yi-Fen Lee
12097-12110
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cooperative interactions between p53 and NFκB enhance cell plasticity

Cooperative interactions between p53 and NFκB enhance cell plasticity

https://doi.org/10.18632/oncotarget.2545

Alessandra Bisio, Judit Zámborszky, Sara Zaccara, Mattia Lion, Toma Tebaldi, Vasundhara Sharma, Ivan Raimondi, Federica Alessandrini, Yari Ciribilli,  and Alberto Inga
12111-12125
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The cylindromatosis gene product, CYLD, interacts with MIB2 to regulate notch signalling

The cylindromatosis gene product, CYLD, interacts with MIB2 to regulate notch signalling

https://doi.org/10.18632/oncotarget.2573

Neil Rajan, Richard J.R. Elliott, Alice Smith, Naomi Sinclair, Sally Swift, Christopher J. Lord,  and Alan Ashworth
12126-12140
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-520d-5p directly targets TWIST1 and downregulates the metastamiR miR-10b

MiR-520d-5p directly targets TWIST1 and downregulates the metastamiR miR-10b

https://doi.org/10.18632/oncotarget.2559

Pinchas Tsukerman, Rachel Yamin, Einat Seidel, Saleh Khawaled, Dominik Schmiedel, Tomer Bar-Mag,  and Ofer Mandelboim
12141-12150
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GLI inhibitor GANT-61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKT-mTOR axis

GLI inhibitor GANT-61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKT-mTOR axis

https://doi.org/10.18632/oncotarget.2569

Ritesh K. Srivastava, Samer Zaid Kaylani, Nayf Edrees, Changzhao Li, Sarang S. Talwelkar, Jianmin Xu, Komaraiah Palle, Joseph G. Pressey,  and Mohammad Athar
12151-12165
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets

Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets

https://doi.org/10.18632/oncotarget.2570

Costa Frangou, Ying-Wei Li, He Shen, Nuo Yang, Kayla E. Wilson, Maxime Blijlevens, Jin Guo, Norma J. Nowak,  and Jianmin Zhang
12166-12176
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Downregulation of microRNA-100 enhances the ICMT-Rac1 signaling and promotes metastasis of hepatocellular carcinoma cells

Downregulation of microRNA-100 enhances the ICMT-Rac1 signaling and promotes metastasis of hepatocellular carcinoma cells

https://doi.org/10.18632/oncotarget.2601

Hui-Chao Zhou, Jian-Hong Fang, Xu Luo, Lei Zhang, Jine Yang, Chong Zhang,  and Shi-Mei Zhuang
12177-12188
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

EBV-driven LMP1 and IFN-γ up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy

EBV-driven LMP1 and IFN-γ up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy

https://doi.org/10.18632/oncotarget.2608

Wenfeng Fang, Jianwei Zhang, Shaodong Hong, Jianhua Zhan, Nan Chen, Tao Qin, Yanna Tang, Yaxiong Zhang, Shiyang Kang, Ting Zhou, Xuan Wu, Wenhua Liang, Zhihuang Hu, Yuxiang Ma, Yuanyuan Zhao, Ying Tian, Yunpeng Yang, Cong Xue, Yue Yan, Xue Hou, Peiyu Huang, Yan Huang, Hongyun Zhao,  and Li Zhang
12189-12202
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CD151-α3β1 integrin complexes suppress ovarian tumor growth by repressing slug-mediated EMT and canonical Wnt signaling

CD151-α3β1 integrin complexes suppress ovarian tumor growth by repressing slug-mediated EMT and canonical Wnt signaling

https://doi.org/10.18632/oncotarget.2622

Lauren A. Baldwin, John T. Hoff, Jason Lefringhouse, Michael Zhang, Changhe Jia, Zeyi Liu, Sonia Erfani, Hongyan Jin, Mei Xu, Qing-Bai She, John R. van Nagell, Chi Wang, Li Chen, Rina Plattner, David M. Kaetzel, Jia Luo, Michael Lu, Dava West, Chunming Liu, Fred R. Ueland, Ronny Drapkin, Binhua P. Zhou,  and Xiuwei H. Yang
12203-12217
Abstract  |  PDF  |  HTML  |  Order a Reprint

A recessive variant of XRCC4 predisposes to non- BRCA1/2 breast cancer in chinese women and impairs the DNA damage response via dysregulated nuclear localization

A recessive variant of XRCC4 predisposes to non- BRCA1/2 breast cancer in chinese women and impairs the DNA damage response via dysregulated nuclear localization

https://doi.org/10.18632/oncotarget.2623

Min He, Xin Hu, Li Chen, A-Yong Cao, Ke-Da Yu, Ting-Yan Shi, Xia-Ying Kuang, Wen-Biao Shi, Hong Ling, Shan Li, Feng Qiao, Ling Yao, Qingyi Wei, Gen-Hong Di,  and Zhi-Ming Shao
12218-12232
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic significance of catalase expression and its regulatory effects on hepatitis B virus X protein (HBx) in HBV-related advanced hepatocellular carcinomas

Prognostic significance of catalase expression and its regulatory effects on hepatitis B virus X protein (HBx) in HBV-related advanced hepatocellular carcinomas

https://doi.org/10.18632/oncotarget.2625

Mi-Young Cho, Jae Youn Cheong, Wonchung Lim, Sujin Jo, Youngsoo Lee, Hee-Jung Wang, Kyou-Hoon Han,  and Hyeseong Cho
12233-12246
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GALNT2 suppresses malignant phenotypes through IGF-1 receptor and predicts favorable prognosis in neuroblastoma

GALNT2 suppresses malignant phenotypes through IGF-1 receptor and predicts favorable prognosis in neuroblastoma

https://doi.org/10.18632/oncotarget.2627

Wan-Ling Ho, Chih-Hsing Chou, Yung-Ming Jeng, Meng-Yao Lu, Yung-Li Yang, Shiann-Tarng Jou, Dong-Tsamn Lin, Hsiu-Hao Chang, Kai-Hsin Lin, Wen-Ming Hsu,  and Min-Chuan Huang
12247-12259
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ZNF282 (Zinc finger protein 282), a novel E2F1 co-activator, promotes esophageal squamous cell carcinoma

ZNF282 (Zinc finger protein 282), a novel E2F1 co-activator, promotes esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.2630

So-Young Yeo, Sang Yun Ha, Eun Ji Yu, Keun-Woo Lee, Jeong Hoon Kim,  and Seok-Hyung Kim
12260-12272
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/β-catenin pathway

Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/β-catenin pathway

https://doi.org/10.18632/oncotarget.2631

Tsai-Hsien Hung, Sheng-Chi Hsu, Ching-Yi Cheng, Kong-Bung Choo, Ching-Ping Tseng, Tse-Ching Chen, Ying-Wei Lan, Tsung-Teng Huang, Hsin-Chih Lai, Chuan-Mu Chen,  and Kowit-Yu Chong
12273-12290
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-373 targeting of the Rab22a oncogene suppresses tumor invasion and metastasis in ovarian cancer

MiR-373 targeting of the Rab22a oncogene suppresses tumor invasion and metastasis in ovarian cancer

https://doi.org/10.18632/oncotarget.2577

Yue Zhang, Fu-Jun Zhao, Li-Lan Chen, Luo-Qiao Wang, Kenneth P. Nephew, Ying-Li Wu,  and Shu Zhang
12291-12303
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeting cytosolic phospholipase A2 α in colorectal cancer cells inhibits constitutively activated protein kinase B (AKT) and cell proliferation

Targeting cytosolic phospholipase A2 α in colorectal cancer cells inhibits constitutively activated protein kinase B (AKT) and cell proliferation

https://doi.org/10.18632/oncotarget.2639

Zhong Zheng, Xiangyi He, Chanlu Xie, Sheng Hua, Jianfang Li, Tingfeng Wang, Mu Yao, Soma Vignarajan, Ying Teng, Leila Hejazi, Bingya Liu,  and Qihan Dong
12304-12316
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The novel IκB kinase β inhibitor IMD-0560 prevents bone invasion by oral squamous cell carcinoma

The novel IκB kinase β inhibitor IMD-0560 prevents bone invasion by oral squamous cell carcinoma

https://doi.org/10.18632/oncotarget.2640

Yukiyo Tada, Shoichiro Kokabu, Goro Sugiyama, Chihiro Nakatomi, Kazuhiro Aoki, Hidefumi Fukushima, Kenji Osawa, Yasutaka Sugamori, Keiichi Ohya, Masato Okamoto, Tomoyuki Fujikawa, Akiko Itai, Kou Matsuo, Seiji Watanabe,  and Eijiro Jimi
12317-12330
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevated endoplasmic reticulum stress reinforced immunosuppression in the tumor microenvironment via myeloid-derived suppressor cells

Elevated endoplasmic reticulum stress reinforced immunosuppression in the tumor microenvironment via myeloid-derived suppressor cells

https://doi.org/10.18632/oncotarget.2589

Bo-Ra Lee, Sun-Young Chang, Eun-Hye Hong, Bo-Eun Kwon, Hong Min Kim, Yeon-Jeong Kim, Jongkook Lee, Hyun-Jong Cho, Jae-Hee Cheon,  and Hyun-Jeong Ko
12331-12345
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and cell line mouse models

Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and cell line mouse models

https://doi.org/10.18632/oncotarget.2641

Yukihiko Hiroshima, Yong Zhang, Takashi Murakami, Ali Maawy, Shinji Miwa, Mako Yamamoto, Shuya Yano, Sho Sato, Masashi Momiyama, Ryutaro Mori, Ryusei Matsuyama, Takashi Chishima, Kuniya Tanaka, Yasushi Ichikawa, Michael Bouvet, Itaru Endo, Ming Zhao,  and Robert M. Hoffman
12346-12357
Abstract  |  PDF  |  HTML  |  Order a Reprint

Bortezomib induces AMPK-dependent autophagosome formation uncoupled from apoptosis in drug resistant cells

Bortezomib induces AMPK-dependent autophagosome formation uncoupled from apoptosis in drug resistant cells

https://doi.org/10.18632/oncotarget.2590

Sajjeev Jaganathan, Ehsan Malek, Subrahmanya Vallabhapurapu, Sivakumar Vallabhapurapu,  and James J. Driscoll
12358-12370
Abstract  |  PDF  |  HTML  |  Order a Reprint

Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia

Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.2642

Houda Alachkar, Martin B.G. Mutonga, Klaus H. Metzeler, Noreen Fulton, Gregory Malnassy, Tobias Herold, Karsten Spiekermann, Stefan K. Bohlander, Wolfgang Hiddemann, Yo Matsuo, Wendy Stock,  and Yusuke Nakamura
12371-12382
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expansion of CTCs from early stage lung cancer patients using a microfluidic co-culture model

Expansion of CTCs from early stage lung cancer patients using a microfluidic co-culture model

https://doi.org/10.18632/oncotarget.2592

Zhuo Zhang, Hiroe Shiratsuchi, Jules Lin, Guoan Chen, Rishindra M. Reddy, Ebrahim Azizi, Shamileh Fouladdel, Andrew C. Chang, Lin Lin, Hui Jiang, Meghna Waghray, Gary Luker, Diane M. Simeone, Max S. Wicha, David G. Beer, Nithya Ramnath,  and Sunitha Nagrath
12383-12397
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value of LAMP3 and TP53 overexpression in benign and malignant gastrointestinal tissues

Prognostic value of LAMP3 and TP53 overexpression in benign and malignant gastrointestinal tissues

https://doi.org/10.18632/oncotarget.2643

Rongwei Sun, Xudong Wang, Huijun Zhu, Haijun Mei, Wei Wang, Shu Zhang,  and Jianfei Huang
12398-12409
Abstract  |  PDF  |  HTML  |  Order a Reprint

Tamoxifen represses alcohol-induced transcription of RNA polymerase III-dependent genes in breast cancer cells

Tamoxifen represses alcohol-induced transcription of RNA polymerase III-dependent genes in breast cancer cells

https://doi.org/10.18632/oncotarget.2678

Qian Zhong, Ganggang Shi, Qingsong Zhang, Lei Lu, Daniel Levy,  and Shuping Zhong
12410-12417
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer

Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer

https://doi.org/10.18632/oncotarget.2628

Julia Femel, Elisabeth J.M. Huijbers, Falk Saupe, Jessica Cedervall, Lei Zhang, Pernilla Roswall, Erik Larsson, Helena Olofsson, Kristian Pietras, Anna Dimberg, Lars Hellman,  and Anna-Karin Olsson
12418-12427
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical Research Papers

TERT promoter mutations are associated with distant metastases in upper tract urothelial carcinomas and serve as urinary biomarkers detected by a sensitive castPCR

TERT promoter mutations are associated with distant metastases in upper tract urothelial carcinomas and serve as urinary biomarkers detected by a sensitive castPCR

https://doi.org/10.18632/oncotarget.2660

Kun Wang, Tiantian Liu, Nan Ge, Li Liu, Xiaotian Yuan, Jikai Liu, Feng Kong, Chang Wang, Hongbo Ren, Keqiang Yan, Sanyuan Hu, Zhonghua Xu, Magnus Björkholm, Yidong Fan, Shengtian Zhao, Cheng Liu,  and Dawei Xu
12428-12439
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comprehensive tumor profiling identifies numerous biomarkers of drug response in cancers of unknown primary site: Analysis of 1806 cases

Comprehensive tumor profiling identifies numerous biomarkers of drug response in cancers of unknown primary site: Analysis of 1806 cases

https://doi.org/10.18632/oncotarget.2574

Zoran Gatalica, Sherri Z. Millis, Semir Vranic, Ryan Bender, Gargi D. Basu, Andreas Voss,  and Daniel D. Von Hoff
12440-12447
Abstract  |  PDF  |  HTML  |  Order a Reprint

Early outcome prediction on 18F-fluorocholine PET/CT in metastatic castration-resistant prostate cancer patients treated with abiraterone

Early outcome prediction on 18F-fluorocholine PET/CT in metastatic castration-resistant prostate cancer patients treated with abiraterone

https://doi.org/10.18632/oncotarget.2558

Ugo De Giorgi, Paola Caroli, Salvatore L. Burgio, Cecilia Menna, Vincenza Conteduca, Emanuela Bianchi, Francesca Fabbri, Elisa Carretta, Dino Amadori, Giovanni Paganelli,  and Federica Matteucci
12448-12458
Abstract  |  PDF  |  HTML  |  Order a Reprint

Increased number of negative lymph nodes is associated with improved cancer specific survival in pathological IIIB and IIIC rectal cancer treated with preoperative radiotherapy

Increased number of negative lymph nodes is associated with improved cancer specific survival in pathological IIIB and IIIC rectal cancer treated with preoperative radiotherapy

https://doi.org/10.18632/oncotarget.2560

Qingguo Li, Changhua Zhuo, Guoxiang Cai, Dawei Li, Lei Liang,  and Sanjun Cai
12459-12471
Abstract  |  PDF  |  HTML  |  Order a Reprint


Copyright © 2017 Impact Journals
Impact Journals is a registered trademark of Impact Journals, LLC