Oncotarget

Vol 5, No 22

November 30, 2014

View Archive »

Order a Reprint

About The Cover

hMENA11a defines an epithelial phenotype and is expressed alternatively to hMENAΔv6 isoform in lung cancer cell lines. See Bria et al.

Table of Contents

Editorial

Tetraploidy and tumor development

Tetraploidy and tumor development

https://doi.org/10.18632/oncotarget.2790

Sanghee Lim,  and Neil J. Ganem
10959-10960
PDF  |  Order a Reprint

Angiostatic vaccines, an underestimated approach of cancer therapy

Angiostatic vaccines, an underestimated approach of cancer therapy

https://doi.org/10.18632/oncotarget.2791

Arjan W. Griffioen
10961-10962
PDF  |  Order a Reprint

ADAM10 and ADAM17: New Players in Trastuzumab Resistance

ADAM10 and ADAM17: New Players in Trastuzumab Resistance

https://doi.org/10.18632/oncotarget.2794

Michael J. Duffy, John Crown,  and Maeve Mullooly
10963-10964
PDF  |  Order a Reprint

Double-punching PMBL

Double-punching PMBL

https://doi.org/10.18632/oncotarget.2827

Jochen K. Lennerz
10965-10966
PDF  |  Order a Reprint

Reciprocity in breast cancer progression

Reciprocity in breast cancer progression

https://doi.org/10.18632/oncotarget.2853

Christian Gespach
10967-10968
PDF  |  Order a Reprint

Reviews

Critical role of NF-κB in pancreatic cancer

Critical role of NF-κB in pancreatic cancer

https://doi.org/10.18632/oncotarget.2624

Lakshmi Prabhu, Rasika Mundade, Murray Korc, Patrick J. Loehrer,  and Tao Lu
10969-10975
Abstract  |  PDF  |  HTML  |  Order a Reprint

A pathophysiological view of the long non-coding RNA world

A pathophysiological view of the long non-coding RNA world

https://doi.org/10.18632/oncotarget.2770

Federico Di Gesualdo, Sergio Capaccioli,  and Matteo Lulli
10976-10996
Abstract  |  PDF  |  HTML  |  Order a Reprint

Research Perspectives

Oncotargeting G proteins: The Hippo in the room

Oncotargeting G proteins: The Hippo in the room

https://doi.org/10.18632/oncotarget.2815

Xiaodong Feng, Qianming Chen,  and J. Silvio Gutkind
10997-10999
Abstract  |  PDF  |  HTML  |  Order a Reprint

Wnt signaling, de novo lipogenesis, adipogenesis and ectopic fat

Wnt signaling, de novo lipogenesis, adipogenesis and ectopic fat

https://doi.org/10.18632/oncotarget.2769

Kangxing Song, Shuxia Wang, Mitra Mani,  and Arya Mani
11000-11003
Abstract  |  PDF  |  HTML  |  Order a Reprint

Bioinformatics analysis of the serine and glycine pathway in cancer cells

Bioinformatics analysis of the serine and glycine pathway in cancer cells

https://doi.org/10.18632/oncotarget.2668

Alexey Antonov, Massimiliano Agostini, Maria Morello, Marilena Minieri, Gerry Melino,  and Ivano Amelio
11004-11013
Abstract  |  PDF  |  HTML  |  Order a Reprint

Revealed: The spy who regulates neuroblastoma stem cells

Revealed: The spy who regulates neuroblastoma stem cells

https://doi.org/10.18632/oncotarget.2839

Parvez Vora, Chitra Venugopal,  and Sheila K. Singh
11014-11016
Abstract  |  PDF  |  HTML  |  Order a Reprint

Priority Research Papers

Surgical procedures and postsurgical tissue processing significantly affect expression of genes and EGFR-pathway proteins in colorectal cancer tissue

Surgical procedures and postsurgical tissue processing significantly affect expression of genes and EGFR-pathway proteins in colorectal cancer tissue

https://doi.org/10.18632/oncotarget.2669

Kerstin A. David, Florian T. Unger, Philipp Uhlig, Hartmut Juhl, Helen M. Moore, Carolyn Compton, Björn Nashan, Arnulf Dörner, Andreas de Weerth,  and Carsten Zornig
11017-11028
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mitochondria as new therapeutic targets for eradicating cancer stem cells: Quantitative proteomics and functional validation via MCT1/2 inhibition

Mitochondria as new therapeutic targets for eradicating cancer stem cells: Quantitative proteomics and functional validation via MCT1/2 inhibition

https://doi.org/10.18632/oncotarget.2789

Rebecca Lamb, Hannah Harrison, James Hulit, Duncan L. Smith, Michael P. Lisanti,  and Federica Sotgia
11029-11037
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Curaxin CBL0137 eradicates drug resistant cancer stem cells and potentiates efficacy of gemcitabine in preclinical models of pancreatic cancer

Curaxin CBL0137 eradicates drug resistant cancer stem cells and potentiates efficacy of gemcitabine in preclinical models of pancreatic cancer

https://doi.org/10.18632/oncotarget.2701

Catherine Burkhart, Daria Fleyshman, Rachael Kohrn, Mairead Commane, Jennifer Garrigan, Vadim Kurbatov, Ilya Toshkov, Rajesh Ramachandran, Laura Martello,  and Katerina V. Gurova
11038-11053
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic impact of alternative splicing-derived hMENA isoforms in resected, node-negative, non-small-cell lung cancer

Prognostic impact of alternative splicing-derived hMENA isoforms in resected, node-negative, non-small-cell lung cancer

https://doi.org/10.18632/oncotarget.2609

Emilio Bria, Francesca Di Modugno, Isabella Sperduti, Pierluigi Iapicca, Paolo Visca, Gabriele Alessandrini, Barbara Antoniani, Sara Pilotto, Vienna Ludovini, Jacopo Vannucci, Guido Bellezza, Angelo Sidoni, Giampaolo Tortora, Derek C. Radisky, Lucio Crinò, Francesco Cognetti, Francesco Facciolo, Marcella Mottolese, Michele Milella,  and Paola Nisticò
11054-11063
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival

IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival

https://doi.org/10.18632/oncotarget.2519

Serena Lunardi, Nigel B. Jamieson, Su Yin Lim, Kristin L. Griffiths, Manuela Carvalho-Gaspar, Osama Al-Assar, Sabira Yameen, Ross C. Carter, Colin J. McKay, Gabriele Spoletini, Stefano D’Ugo, Michael A. Silva, Owen J. Sansom, Klaus-Peter Janssen, Ruth J. Muschel,  and Thomas B. Brunner
11064-11080
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

NBN gain is predictive for adverse outcome following image-guided radiotherapy for localized prostate cancer

NBN gain is predictive for adverse outcome following image-guided radiotherapy for localized prostate cancer

https://doi.org/10.18632/oncotarget.2404

Alejandro Berlin, Emilie Lalonde, Jenna Sykes, Gaetano Zafarana, Kenneth C. Chu, Varune R. Ramnarine, Adrian Ishkanian, Dorota H.S. Sendorek, Ivan Pasic, Wan L. Lam, Igor Jurisica, Theo van der Kwast, Michael Milosevic, Paul C. Boutros,  and Robert G. Bristow
11081-11090
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Development and prospective multicenter evaluation of the long noncoding RNA MALAT-1 as a diagnostic urinary biomarker for prostate cancer

Development and prospective multicenter evaluation of the long noncoding RNA MALAT-1 as a diagnostic urinary biomarker for prostate cancer

https://doi.org/10.18632/oncotarget.2691

Fubo Wang, Shancheng Ren, Rui Chen, Ji Lu, Xiaolei Shi, Yasheng Zhu, Wei Zhang, Taile Jing, Chao Zhang, Jian Shen, Chuanliang Xu, Huiqing Wang, Haifeng Wang, Yang Wang, Bin Liu, Yaoming Li, Ziyu Fang, Fei Guo, Meng Qiao, Chengyao Wu, Qiang Wei, Danfeng Xu, Dan Shen, Xin Lu, Xu Gao, Jianguo Hou,  and Yinghao Sun
11091-11102
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical significance and therapeutic value of glutathione peroxidase 3 (GPx3) in hepatocellular carcinoma

Clinical significance and therapeutic value of glutathione peroxidase 3 (GPx3) in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.2549

Xiang Qi, Kevin Tak Pan Ng, Qi Zhou Lian, Xiao Bing Liu, Chang Xian Li, Wei Geng, Chang Chun Ling, Yuen Yuen Ma, Wai Ho Yeung, Wen Wei Tu, Sheung Tat Fan, Chung Mau Lo,  and Kwan Man
11103-11120
Abstract  |  HTML  |  PDF  |  Supplementary Information  |  Order a Reprint

Peritumoral Neuropilin-1 and VEGF receptor-2 expression increases time to recurrence in hepatocellular carcinoma patients undergoing curative hepatectomy

Peritumoral Neuropilin-1 and VEGF receptor-2 expression increases time to recurrence in hepatocellular carcinoma patients undergoing curative hepatectomy

https://doi.org/10.18632/oncotarget.2553

Peng-Yuan Zhuang, Jian-Dong Wang, Zhao-Hui Tang, Xue-Ping Zhou, Yong Yang, Zhi-Wei Quan, Ying-Bin Liu,  and Jun Shen
11121-11132
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The role of systemic chemotherapy and multidisciplinary management in improving the overall survival of patients with metastatic squamous cell carcinoma of the anal canal

The role of systemic chemotherapy and multidisciplinary management in improving the overall survival of patients with metastatic squamous cell carcinoma of the anal canal

https://doi.org/10.18632/oncotarget.2563

Cathy Eng, George J. Chang, Y. Nancy You, Prajnan Das, Miguel Rodriguez-Bigas, Yan Xing, Jean-Nicolas Vauthey, Jane E. Rogers, Aki Ohinata, Priyanka Pathak, Salil Sethi, Jonathan K. Phillips, Christopher H. Crane,  and Robert A. Wolff
11133-11142
Abstract  |  PDF  |  HTML  |  Order a Reprint

Intermediate neoadjuvant radiotherapy for T3 low/middle rectal cancer: postoperative outcomes of a non-controlled clinical trial

Intermediate neoadjuvant radiotherapy for T3 low/middle rectal cancer: postoperative outcomes of a non-controlled clinical trial

https://doi.org/10.18632/oncotarget.2603

Giovanni Bisceglia, Nicola Mastrodonato, Berardino Tardio, Gianluigi Mazzoccoli, Pietro Corsa, Michele Troiano,  and Salvatore Parisi
11143-11153
Abstract  |  PDF  |  HTML  |  Order a Reprint

A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours

A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours

https://doi.org/10.18632/oncotarget.2568

David S. Hong, Razelle Kurzrock, Marilyn Mulay, Erik Rasmussen, Benjamin M. Wu, Michael B. Bass, Zhandong D. Zhong, Greg Friberg,  and Lee S. Rosen
11154-11167
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeted PI3K/AKT/mTOR therapy for metastatic carcinomas of the cervix: A phase I clinical experience

Targeted PI3K/AKT/mTOR therapy for metastatic carcinomas of the cervix: A phase I clinical experience

https://doi.org/10.18632/oncotarget.2584

Ming-Mo Hou, Xiaochun Liu, Jennifer Wheler, Aung Naing, David Hong, Robert L. Coleman, Apostolia Tsimberidou, Filip Janku, Ralph Zinner, Karen Lu, Razelle Kurzrock,  and Siqing Fu
11168-11179
Abstract  |  PDF  |  HTML  |  Order a Reprint

Research Papers

Neuroblastoma in dialog with its stroma: NTRK1 is a regulator of cellular cross-talk with Schwann cells

Neuroblastoma in dialog with its stroma: NTRK1 is a regulator of cellular cross-talk with Schwann cells

https://doi.org/10.18632/oncotarget.2611

Kristian W. Pajtler, Ellen Mahlow, Andrea Odersky, Sven Lindner, Harald Stephan, Ivo Bendix, Angelika Eggert, Alexander Schramm,  and Johannes H. Schulte
11180-11192
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The IGF-1 receptor inhibitor picropodophyllin potentiates the anti-myeloma activity of a BH3-mimetic

The IGF-1 receptor inhibitor picropodophyllin potentiates the anti-myeloma activity of a BH3-mimetic

https://doi.org/10.18632/oncotarget.1933

Liesbeth Bieghs, Susanne Lub, Karel Fostier, Ken Maes, Els Van Valckenborgh, Eline Menu, Hans E. Johnsen, Michael T. Overgaard, Olle Larsson, Magnus Axelson, Mette Nyegaard, Rik Schots, Helena Jernberg-Wiklund, Karin Vanderkerken,  and Elke De Bruyne
11193-11208
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of Lon blocks cell proliferation, enhances chemosensitivity by promoting apoptosis and decreases cellular bioenergetics of bladder cancer: potential roles of Lon as a prognostic marker and therapeutic target in baldder cancer

Inhibition of Lon blocks cell proliferation, enhances chemosensitivity by promoting apoptosis and decreases cellular bioenergetics of bladder cancer: potential roles of Lon as a prognostic marker and therapeutic target in baldder cancer

https://doi.org/10.18632/oncotarget.2026

Yongzhang Liu, Linhua Lan, Kate Huang, Rongrong Wang, Cuicui Xu, Yang Shi, Xiaoyi Wu, Zhi Wu, Jiliang Zhang, Lin Chen, Lu Wang, Xiaomin Yu, Haibo Zhu,  and Bin Lu
11209-11224
Abstract  |  PDF  |  HTML  |  Order a Reprint

Maspin expression in prostate tumor elicits host anti-tumor immunity

Maspin expression in prostate tumor elicits host anti-tumor immunity

https://doi.org/10.18632/oncotarget.2615

Sijana H. Dzinic, Kang Chen, Archana Thakur, Alexander Kaplun, R. Daniel Bonfil, Xiaohua Li, Jason Liu, M. Margarida Bernardo, Allen Saliganan, Jessica B. Back, Hiroshi Yano, Dana L. Schalk, Elyse N. Tomaszewski, Ahmed S. Beydoun, Gregory Dyson, Adelina Mujagic, David Krass, Ivory Dean, Qing-Sheng Mi, Elisabeth Heath, Wael Sakr, Lawrence G. Lum,  and Shijie Sheng
11225-11236
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Noxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cells

Noxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cells

https://doi.org/10.18632/oncotarget.2616

Yi Lun Liu, Fritz Lai, James S. Wilmott, Xu Guang Yan, Xiao Ying Liu, Qi Luan, Su Tang Guo, Chen Chen Jiang, Hsin-Yi Tseng, Richard A. Scolyer, Lei Jin,  and Xu Dong Zhang
11237-11251
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current

Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current

https://doi.org/10.18632/oncotarget.2617

Marta Gritti, Roberto Würth, Marina Angelini, Federica Barbieri, Marta Peretti, Erika Pizzi, Alessandra Pattarozzi, Elisa Carra, Rodolfo Sirito, Antonio Daga, Paul M.G. Curmi, Michele Mazzanti,  and Tullio Florio
11252-11268
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Apoptin enhances the oncolytic properties of vaccinia virus and modifies mechanisms of tumor regression

Apoptin enhances the oncolytic properties of vaccinia virus and modifies mechanisms of tumor regression

https://doi.org/10.18632/oncotarget.2579

Galina Kochneva, Evgeniy Zonov, Antonina Grazhdantseva, Anastasiya Yunusova, Galina Sibolobova, Evgeniy Popov, Oleg Taranov, Sergei Netesov, Peter Chumakov,  and Elena Ryabchikova
11269-11282
Abstract  |  PDF  |  HTML  |  Order a Reprint

Multiple myeloma cells recruit tumor-supportive macrophages through the CXCR4/CXCL12 axis and promote their polarization toward the M2 phenotype

Multiple myeloma cells recruit tumor-supportive macrophages through the CXCR4/CXCL12 axis and promote their polarization toward the M2 phenotype

https://doi.org/10.18632/oncotarget.2207

Katia Beider, Hanna Bitner, Merav Leiba, Odit Gutwein, Maya Koren-Michowitz, Olga Ostrovsky, Michal Abraham, Hanna Wald, Eithan Galun, Amnon Peled,  and Arnon Nagler
11283-11296
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

DNA mismatch repair gene MLH1 induces apoptosis in prostate cancer cells

DNA mismatch repair gene MLH1 induces apoptosis in prostate cancer cells

https://doi.org/10.18632/oncotarget.2315

Shinichiro Fukuhara, Inik Chang, Yozo Mitsui, Takeshi Chiyomaru, Soichiro Yamamura, Shahana Majid, Sharanjot Saini, Hiroshi Hirata, Guoren Deng, Ankurpreet Gill, Darryn K. Wong, Hiroaki Shiina, Norio Nonomura, Rajvir Dahiya,  and Yuichiro Tanaka
11297-11307
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Therapeutic potential of ERK5 targeting in triple negative breast cancer

Therapeutic potential of ERK5 targeting in triple negative breast cancer

https://doi.org/10.18632/oncotarget.2324

María Jesús Ortiz-Ruiz, Stela Álvarez-Fernández, Tracy Parrott, Sara Zaknoen, Francis J. Burrows, Alberto Ocaña, Atanasio Pandiella,  and Azucena Esparís-Ogando
11308-11318
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

EZH2 promotes angiogenesis through inhibition of miR-1/Endothelin-1 axis in nasopharyngeal carcinoma

EZH2 promotes angiogenesis through inhibition of miR-1/Endothelin-1 axis in nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.2435

Juan Lu, Fei-Peng Zhao, Zengliu Peng, Meng-Wen Zhang, Shao-Xiong Lin, Bi-Jun Liang, Bao Zhang, Xiong Liu, Lu Wang, Gang Li, Wen-Dong Tian, Ying Peng, Ming-Liang He,  and Xiang-Ping Li
11319-11332
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression of human β-defensin 2 promotes growth and invasion during esophageal carcinogenesis

Overexpression of human β-defensin 2 promotes growth and invasion during esophageal carcinogenesis

https://doi.org/10.18632/oncotarget.2416

Ni Shi, Feng Jin, Xiaoli Zhang, Steven K. Clinton, Zui Pan,  and Tong Chen
11333-11344
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Interactome analysis of myeloid-derived suppressor cells in murine models of colon and breast cancer

Interactome analysis of myeloid-derived suppressor cells in murine models of colon and breast cancer

https://doi.org/10.18632/oncotarget.2489

Alexander M. Aliper, Victoria P. Frieden-Korovkina, Anton Buzdin, Sergey A. Roumiantsev,  and Alex Zhavoronkov
11345-11353
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification and validation of p50 as the cellular target of eriocalyxin B

Identification and validation of p50 as the cellular target of eriocalyxin B

https://doi.org/10.18632/oncotarget.2461

Ling-Mei Kong, Xu Deng, Zhi-Li Zuo, Han-Dong Sun, Qin-Shi Zhao,  and Yan Li
11354-11364
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting of mutant p53-induced FoxM1 with thiostrepton induces cytotoxicity and enhances carboplatin sensitivity in cancer cells

Targeting of mutant p53-induced FoxM1 with thiostrepton induces cytotoxicity and enhances carboplatin sensitivity in cancer cells

https://doi.org/10.18632/oncotarget.2497

Xuan Zhang, Lihua Cheng, Kay Minn, Rashna Madan, Andrew K. Godwin, Viji Shridhar,  and Jeremy Chien
11365-11380
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Human PIF1 helicase supports DNA replication and cell growth under oncogenic-stress

Human PIF1 helicase supports DNA replication and cell growth under oncogenic-stress

https://doi.org/10.18632/oncotarget.2501

Mary E. Gagou, Anil Ganesh, Geraldine Phear, Darren Robinson, Eva Petermann, Angela Cox,  and Mark Meuth
11381-11398
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Bcl-2 family inhibition sensitizes human prostate cancer cells to docetaxel and promotes unexpected apoptosis under caspase-9 inhibition

Bcl-2 family inhibition sensitizes human prostate cancer cells to docetaxel and promotes unexpected apoptosis under caspase-9 inhibition

https://doi.org/10.18632/oncotarget.2550

Hiroki Tamaki, Nanae Harashima, Miho Hiraki, Naoko Arichi, Nobuhiro Nishimura, Hiroaki Shiina, Kohji Naora,  and Mamoru Harada
11399-11412
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Chemopreventive apigenin controls UVB-induced cutaneous proliferation and angiogenesis through HuR and thrombospondin-1

Chemopreventive apigenin controls UVB-induced cutaneous proliferation and angiogenesis through HuR and thrombospondin-1

https://doi.org/10.18632/oncotarget.2551

Xin Tong, Salida Mirzoeva, Dorina Veliceasa, Bryan B. Bridgeman, Philip Fitchev, Mona L. Cornwell, Susan E. Crawford, Jill C. Pelling,  and Olga V. Volpert
11413-11427
Abstract  |  HTML  |  PDF  |  Supplementary Information  |  Order a Reprint

Downregulated MTAP expression in myxofibrosarcoma: A characterization of inactivating mechanisms, tumor suppressive function, and therapeutic relevance

Downregulated MTAP expression in myxofibrosarcoma: A characterization of inactivating mechanisms, tumor suppressive function, and therapeutic relevance

https://doi.org/10.18632/oncotarget.2552

Chien-Feng Li, Fu-Min Fang, Hsing-Jien Kung, Li-Tzong Chen, Jun-Wen Wang, Jen-Wei Tsai, Shih Chen Yu, Yu-Hui Wang, Shau-Hsuan Li,  and Hsuan-Ying Huang
11428-11441
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Senescence of tumor cells induced by oxaliplatin increases the efficiency of a lipid A immunotherapy via the recruitment of neutrophils

Senescence of tumor cells induced by oxaliplatin increases the efficiency of a lipid A immunotherapy via the recruitment of neutrophils

https://doi.org/10.18632/oncotarget.2556

Cédric Seignez, Amandine Martin, Claire-Emmanuelle Rollet, Cindy Racoeur, Alessandra Scagliarini, Jean-François Jeannin, Ali Bettaieb,  and Catherine Paul
11442-11451
Abstract  |  PDF  |  HTML  |  Order a Reprint

Pharmacological induction of cell surface GRP78 contributes to apoptosis in triple negative breast cancer cells

Pharmacological induction of cell surface GRP78 contributes to apoptosis in triple negative breast cancer cells

https://doi.org/10.18632/oncotarget.2576

Annat Raiter, Rinat Yerushalmi,  and Britta Hardy
11452-11463
Abstract  |  PDF  |  HTML  |  Order a Reprint

Human recombinant truncated RNASET2, devoid of RNase activity; A potential cancer therapeutic agent

Human recombinant truncated RNASET2, devoid of RNase activity; A potential cancer therapeutic agent

https://doi.org/10.18632/oncotarget.2562

Liron Nesiel-Nuttman, Betty Schwartz,  and Oded Shoseyov
11464-11478
Abstract  |  PDF  |  HTML  |  Order a Reprint

Mastl kinase, a promising therapeutic target, promotes cancer recurrence

Mastl kinase, a promising therapeutic target, promotes cancer recurrence

https://doi.org/10.18632/oncotarget.2565

Ling Wang, Vivian Q. Luong, Peter J. Giannini,  and Aimin Peng
11479-11489
Abstract  |  PDF  |  HTML  |  Order a Reprint

CXCL12/CXCR4 signaling counteracts docetaxel-induced microtubule stabilization via p21-activated kinase 4-dependent activation of LIM domain kinase 1

CXCL12/CXCR4 signaling counteracts docetaxel-induced microtubule stabilization via p21-activated kinase 4-dependent activation of LIM domain kinase 1

https://doi.org/10.18632/oncotarget.2571

Arun Bhardwaj, Sanjeev K. Srivastava, Seema Singh, Sumit Arora, Nikhil Tyagi, Joel Andrews, Steven McClellan, James E. Carter,  and Ajay P. Singh
11490-11500
Abstract  |  PDF  |  HTML  |  Order a Reprint

Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support

Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support

https://doi.org/10.18632/oncotarget.2572

Jeannette Boutter, Yun Huang, Blerim Marovca, Andreas Vonderheit, Michael A. Grotzer, Cornelia Eckert, Gunnar Cario, Bernd Wollscheid, Peter Horvath, Beat C. Bornhauser,  and Jean-Pierre Bourquin
11501-11512
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

STAT3 inhibition suppresses proliferation of retinoblastoma through down-regulation of positive feedback loop of STAT3/miR-17-92 clusters

STAT3 inhibition suppresses proliferation of retinoblastoma through down-regulation of positive feedback loop of STAT3/miR-17-92 clusters

https://doi.org/10.18632/oncotarget.2546

Dong Hyun Jo, Jin Hyoung Kim, Chang Sik Cho, Young-Lai Cho, Hyoung Oh Jun, Young Suk Yu, Jeong-Ki Min,  and Jeong Hun Kim
11513-11525
Abstract  |  HTML  |  PDF  |  Supplementary Information  |  Order a Reprint

A novel DAG-dependent mechanism links PKCɑ and Cyclin B1 regulating cell cycle progression

A novel DAG-dependent mechanism links PKCɑ and Cyclin B1 regulating cell cycle progression

https://doi.org/10.18632/oncotarget.2578

Alessandro Poli, Giulia Ramazzotti, Alessandro Matteucci, Lucia Manzoli, Annalisa Lonetti, Pann-Ghill Suh, James A. McCubrey,  and Lucio Cocco
11526-11540
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of glioblastoma malignancy by Lgl1

Inhibition of glioblastoma malignancy by Lgl1

https://doi.org/10.18632/oncotarget.2580

Alexander Gont, Jennifer E. L. Hanson, Sylvie J. Lavictoire, Manijeh Daneshmand, Garth Nicholas, John Woulfe, Amin Kassam, Vasco F. Da Silva,  and Ian A. J. Lorimer
11541-11551
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Methylation of miR-129-5p CpG island modulates multi-drug resistance in gastric cancer by targeting ABC transporters

Methylation of miR-129-5p CpG island modulates multi-drug resistance in gastric cancer by targeting ABC transporters

https://doi.org/10.18632/oncotarget.2594

Qiong Wu, Zhiping Yang, Lin Xia, Yongzhan Nie, Kaichun Wu, Yongquan Shi,  and Daiming Fan
11552-11563
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High Id1 expression, a generally negative prognostic factor, paradoxically predicts a favorable prognosis for adjuvant paclitaxel plus cisplatin therapy in surgically treated lung cancer patients

High Id1 expression, a generally negative prognostic factor, paradoxically predicts a favorable prognosis for adjuvant paclitaxel plus cisplatin therapy in surgically treated lung cancer patients

https://doi.org/10.18632/oncotarget.2595

Yu-Jen Cheng, Yi-Chen Lee, Wen-Chin Chiu, Jen-Wei Tsai, Yu-Han Su, Amos C. Hung, Po-Chih Chang, Chih-Jen Huang, Chee-Yin Chai,  and Shyng-Shiou F. Yuan
11564-11575
Abstract  |  PDF  |  HTML  |  Order a Reprint

Suppression of esophageal tumor growth and chemoresistance by directly targeting the PI3K/AKT pathway

Suppression of esophageal tumor growth and chemoresistance by directly targeting the PI3K/AKT pathway

https://doi.org/10.18632/oncotarget.2596

Bin Li, Jin Li, Wen Wen Xu, Xin Yuan Guan, Yan Ru Qin, Li Yi Zhang, Simon Law, Sai Wah Tsao,  and Annie L.M. Cheung
11576-11587
Abstract  |  PDF  |  HTML  |  Order a Reprint

AMACR amplification and overexpression in primary imatinib-naïve gastrointestinal stromal tumors: a driver of cell proliferation indicating adverse prognosis

AMACR amplification and overexpression in primary imatinib-naïve gastrointestinal stromal tumors: a driver of cell proliferation indicating adverse prognosis

https://doi.org/10.18632/oncotarget.2597

Chien-Feng Li, Li-Tzong Chen, Jui Lan, Fong-Fu Chou, Ching-Yih Lin, Yen-Yang Chen, Tzu-Ju Chen, Shau-Hsuan Li, Shih-Chen Yu, Fu-Ming Fang, Hui-Chun Tai,  and Hsuan-Ying Huang
11588-11603
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RYBP expression is associated with better survival of patients with hepatocellular carcinoma (HCC) and responsiveness to chemotherapy of HCC cells in vitro and in vivo

RYBP expression is associated with better survival of patients with hepatocellular carcinoma (HCC) and responsiveness to chemotherapy of HCC cells in vitro and in vivo

https://doi.org/10.18632/oncotarget.2598

Wei Wang, Jianwen Cheng, Jiang-Jiang Qin, Sukesh Voruganti, Subhasree Nag, Jia Fan, Qiang Gao,  and Ruiwen Zhang
11604-11619
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activation of miR-9 by human papillomavirus in cervical cancer

Activation of miR-9 by human papillomavirus in cervical cancer

https://doi.org/10.18632/oncotarget.2599

Weijun Liu, Ge Gao, Xiaoxia Hu, Yuhui Wang, Julie K. Schwarz, Jason J. Chen, Perry W. Grigsby,  and Xiaowei Wang
11620-11630
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Down-regulation of miR-203 induced by Helicobacter pylori infection promotes the proliferation and invasion of gastric cancer by targeting CASK

Down-regulation of miR-203 induced by Helicobacter pylori infection promotes the proliferation and invasion of gastric cancer by targeting CASK

https://doi.org/10.18632/oncotarget.2600

Xiaoying Zhou, Guifang Xu, Chengqiang Yin, Wujuan Jin,  and Guoxin Zhang
11631-11640
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cisplatin in combination with Phenethyl Isothiocyanate (PEITC), a potential new therapeutic strategy for malignant pleural mesothelioma

Cisplatin in combination with Phenethyl Isothiocyanate (PEITC), a potential new therapeutic strategy for malignant pleural mesothelioma

https://doi.org/10.18632/oncotarget.2604

Iza Denis, Laurent Cellerin, Marc Gregoire,  and Christophe Blanquart
11641-11652
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dysregulation of autophagy in human follicular lymphoma is independent of overexpression of BCL-2

Dysregulation of autophagy in human follicular lymphoma is independent of overexpression of BCL-2

https://doi.org/10.18632/oncotarget.2605

Aine McCarthy, Jacek Marzec, Andrew Clear, Robert D. Petty, Rita Coutinho, Janet Matthews, Andrew Wilson, Sameena Iqbal, Maria Calaminici, John G. Gribben,  and Li Jia
11653-11668
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-9 promotes tumor metastasis via repressing E-cadherin in esophageal squamous cell carcinoma

MicroRNA-9 promotes tumor metastasis via repressing E-cadherin in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.2581

Ye Song, Jiangchao Li, Yinghui Zhu, Yongdong Dai, Tingting Zeng, Lulu Liu, Jianbiao Li, Hongbo Wang, Yanru Qin, Musheng Zeng, Xin-Yuan Guan,  and Yan Li
11669-11680
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Suppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosis

Suppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosis

https://doi.org/10.18632/oncotarget.2585

Xing Liu, Xiaofeng Wang, Wenzhong Du, Lingchao Chen, Guangzhi Wang, Yuqiong Cui, Yang Liu, Zhijin Dou, Hongjun Wang, Ping Zhang, Liang Chang, Liye Yi, Jinquan Cai,  and Chuanlu Jiang
11681-11694
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gastrokine 1 induces senescence and apoptosis through regulating telomere length in gastric cancer

Gastrokine 1 induces senescence and apoptosis through regulating telomere length in gastric cancer

https://doi.org/10.18632/oncotarget.2586

Jung Hwan Yoon, Ho Seok Seo, Won Seok Choi, Olga Kim, Suk Woo Nam, Jung Young Lee,  and Won Sang Park
11695-11708
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma

Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma

https://doi.org/10.18632/oncotarget.2606

Ambrish Kumar, Nadia Al-Sammarraie, Donald J. DiPette,  and Ugra S. Singh
11709-11722
Abstract  |  PDF  |  HTML  |  Order a Reprint

MTOR inhibition enhances NVP-AUY922-induced autophagy-mediated KIT degradation and cytotoxicity in imatinib-resistant gastrointestinal stromal tumors

MTOR inhibition enhances NVP-AUY922-induced autophagy-mediated KIT degradation and cytotoxicity in imatinib-resistant gastrointestinal stromal tumors

https://doi.org/10.18632/oncotarget.2607

Yuan-Shuo Hsueh, Hui Hua Chang, Nai-Jung Chiang, Chueh-Chuan Yen, Chien-Feng Li,  and Li-Tzong Chen
11723-11736
Abstract  |  PDF  |  HTML  |  Order a Reprint

Human rpL3 plays a crucial role in cell response to nucleolar stress induced by 5-FU and L-OHP

Human rpL3 plays a crucial role in cell response to nucleolar stress induced by 5-FU and L-OHP

https://doi.org/10.18632/oncotarget.2591

Davide Esposito, Elvira Crescenzi, Vinay Sagar, Fabrizio Loreni, Annapina Russo,  and Giulia Russo
11737-11751
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint


Copyright © 2017 Impact Journals
Impact Journals is a registered trademark of Impact Journals, LLC