Oncotarget

Vol 5, No 16

August 30, 2014

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About The Cover

Comparison of ploidy of chromosome 8 in CTCs before and after treatment. Images of CTCs with different ploidies of chromosome 8: iamge with > 5 copies shown. See Li et al.

Table of Contents

Editorial

Targeting primary mediastinal B-cell lymphoma

Targeting primary mediastinal B-cell lymphoma

https://doi.org/10.18632/oncotarget.2351

Simon D. Wagner
6552-6553
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Spy1/SpeedyA accelerates neuroblastoma

Spy1/SpeedyA accelerates neuroblastoma

https://doi.org/10.18632/oncotarget.2380

Xavier Bisteau,  and Philipp Kaldis
6554-6555
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Chemoprevention of metastasis

Chemoprevention of metastasis

https://doi.org/10.18632/oncotarget.2382

Nancy J. Emenaker, Enrique Zudaire,  and Brad St. Croix
6556-6557
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Reviews

HDAC inhibitors and immunotherapy; a double edged sword?

HDAC inhibitors and immunotherapy; a double edged sword?

https://doi.org/10.18632/oncotarget.2289

Michiel Kroesen, Paul R. Gielen, Ingrid C. Brok, Inna Armandari, Peter M. Hoogerbrugge,  and Gosse J. Adema
6558-6572
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Research Perspectives

Enteric pathogens and cellular transformation: bridging the gaps

Enteric pathogens and cellular transformation: bridging the gaps

https://doi.org/10.18632/oncotarget.2384

Shahid Umar
6573-6575
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Clinical Research Papers

Upregulation of chemokine receptor CCR10 is essential for glioma proliferation, invasion and patient survival

Upregulation of chemokine receptor CCR10 is essential for glioma proliferation, invasion and patient survival

https://doi.org/10.18632/oncotarget.2134

Lingchao Chen, Xing Liu, Hai-Yan Zhang, Wenzong Du, Zhiyong Qin, Yu Yao, Ying Mao,  and Liangfu Zhou
6576-6583
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Preoperative chemotherapy prior to pulmonary metastasectomy in surgically resected primary colorectal carcinoma

Preoperative chemotherapy prior to pulmonary metastasectomy in surgically resected primary colorectal carcinoma

https://doi.org/10.18632/oncotarget.2172

Ishwaria M. Subbiah, Shanda H. Blackmon, Arlene M. Correa, Bryan Kee, Ara A. Vaporciyan, Stephen G. Swisher,  and Cathy Eng
6584-6593
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Clinical significance of phenotyping and karyotyping of circulating tumor cells in patients with advanced gastric cancer

Clinical significance of phenotyping and karyotyping of circulating tumor cells in patients with advanced gastric cancer

https://doi.org/10.18632/oncotarget.2175

Yilin Li, Xiaotian Zhang, Sai Ge, Jing Gao, Jifang Gong, Ming Lu, Qiyue Zhang, Yanshuo Cao, Daisy Dandan Wang, Peter Ping Lin,  and Lin Shen
6594-6602
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Genome-wide DNA methylation and gene expression patterns provide insight into polycystic ovary syndrome development

Genome-wide DNA methylation and gene expression patterns provide insight into polycystic ovary syndrome development

https://doi.org/10.18632/oncotarget.2224

Xiu-Xia Wang, Jing-Zan Wei, Jiao Jiao, Shu-Yi Jiang, Da-Hai Yu,  and Da Li
6603-6610
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Circulating miR-182 is a biomarker of colorectal adenocarcinoma progression

Circulating miR-182 is a biomarker of colorectal adenocarcinoma progression

https://doi.org/10.18632/oncotarget.2245

Lisa Perilli, Caterina Vicentini, Marco Agostini, Silvia Pizzini, Marco Pizzi, Edoardo D’ D. Angelo, Stefania Bortoluzzi, Susanna Mandruzzato, Enzo Mammano, Massimo Rugge, Donato Nitti, Aldo Scarpa, Matteo Fassan,  and Paola Zanovello
6611-6619
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Epidermal growth factor receptor (EGFR) is an independent adverse prognostic factor in esophageal adenocarcinoma patients treated with cisplatin-based neoadjuvant chemotherapy

Epidermal growth factor receptor (EGFR) is an independent adverse prognostic factor in esophageal adenocarcinoma patients treated with cisplatin-based neoadjuvant chemotherapy

https://doi.org/10.18632/oncotarget.2268

Michaela Aichler, Martin Motschmann, Uta Jütting, Birgit Luber, Karen Becker, Katja Ott, Florian Lordick, Rupert Langer, Marcus Feith, Jörg Rüdiger Siewert,  and Axel Walch
6620-6632
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Research Papers

ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer

ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer

https://doi.org/10.18632/oncotarget.1955

Katharina Feldinger, Daniele Generali, Gabriela Kramer-Marek, Merel Gijsen, Tzi Bun Ng, Jack Ho Wong, Carla Strina, Mariarosa Cappelletti, Daniele Andreis, Ji-Liang Li, Esther Bridges, Helen Turley, Russell Leek, Ioannis Roxanis, Jacek Capala, Gillian Murphy, Adrian L. Harris,  and Anthony Kong
6633-6646
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Denosumab mimics the natural decoy receptor osteoprotegerin by interacting with its major binding site on RANKL

Denosumab mimics the natural decoy receptor osteoprotegerin by interacting with its major binding site on RANKL

https://doi.org/10.18632/oncotarget.2160

Aneta Schieferdecker, Mareike Voigt, Kristoffer Riecken, Friederike Braig, Thorsten Schinke, Sonja Loges, Carsten Bokemeyer, Boris Fehse,  and Mascha Binder
6647-6653
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The miR-124-Prolyl Hydroxylase P4HA1-MMP1 axis plays a critical role in prostate cancer progression

The miR-124-Prolyl Hydroxylase P4HA1-MMP1 axis plays a critical role in prostate cancer progression

https://doi.org/10.18632/oncotarget.2208

Balabhadrapatruni V. S. K. Chakravarthi, Satya S. Pathi, Moloy T. Goswami, Marcin Cieślik, Heng Zheng, Sivakumar Nallasivam, Subramanyeswara R. Arekapudi, Xiaojun Jing, Javed Siddiqui, Jyoti Athanikar, Shannon L. Carskadon, Robert J. Lonigro, Lakshmi P. Kunju, Arul M. Chinnaiyan, Nallasivam Palanisamy,  and Sooryanarayana Varambally
6654-6669
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Fructose-2,6-Bisphosphate synthesis by 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase 4 (PFKFB4) is required for the glycolytic response to hypoxia and tumor growth

Fructose-2,6-Bisphosphate synthesis by 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase 4 (PFKFB4) is required for the glycolytic response to hypoxia and tumor growth

https://doi.org/10.18632/oncotarget.2213

Jason Chesney, Jennifer Clark, Alden C. Klarer, Yoannis Imbert-Fernandez, Andrew N. Lane,  and Sucheta Telang
6670-6686
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Systemic miRNA-7 delivery inhibits tumor angiogenesis and growth in murine xenograft glioblastoma

Systemic miRNA-7 delivery inhibits tumor angiogenesis and growth in murine xenograft glioblastoma

https://doi.org/10.18632/oncotarget.2235

Negar Babae, Meriem Bourajjaj, Yijia Liu, Judy R. Van Beijnum, Francesco Cerisoli, Puthupparampil V. Scaria, Mark Verheul, Maaike P. Van Berkel, Ebel H. E. Pieters, Rick J. Van Haastert, Afrouz Yousefi, Enrico Mastrobattista, Gert Storm, Eugene Berezikov, Edwin Cuppen, Martin Woodle, Roel Q. J. Schaapveld, Gregoire P. Prevost, Arjan W. Griffioen, Paula I. Van Noort,  and Raymond M. Schiffelers
6687-6700
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DNA methylation-mediated silencing of matricellular protein dermatopontin promotes hepatocellular carcinoma metastasis by α3β1 integrin-Rho GTPase signaling

DNA methylation-mediated silencing of matricellular protein dermatopontin promotes hepatocellular carcinoma metastasis by α3β1 integrin-Rho GTPase signaling

https://doi.org/10.18632/oncotarget.2239

Ying Fu, Ming-Xuan Feng, Jian Yu, Ming-Ze Ma Ma, Xiao-Jin Liu, Jun Li, Xiao-Mei Yang, Ya-Hui Wang, Yan-Li Zhang, Jun-Ping Ao, Feng Xue, Wenxin Qin, Jianren Gu, Qiang Xia,  and Zhi-Gang Zhang
6701-6715
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Ablation of EIF5A2 induces tumor vasculature remodeling and improves tumor response to chemotherapy via regulation of matrix metalloproteinase 2 expression

Ablation of EIF5A2 induces tumor vasculature remodeling and improves tumor response to chemotherapy via regulation of matrix metalloproteinase 2 expression

https://doi.org/10.18632/oncotarget.2236

Feng-Wei Wang, Mu-Yan Cai, Shi-Juan Mai, Jie-Wei Chen, Hai-Yan Bai, Yan Li, Yi-Ji Liao, Chang-Peng Li, Xiao-Peng Tian, Hsiang-Fu Kung, Xin-Yuan Guan,  and Dan Xie
6716-6733
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RASAL2 down-regulation in ovarian cancer promotes epithelial-mesenchymal transition and metastasis

RASAL2 down-regulation in ovarian cancer promotes epithelial-mesenchymal transition and metastasis

https://doi.org/10.18632/oncotarget.2244

Yuting Huang, Meng Zhao, Haixu Xu, Ke Wang, Zheng Fu, Yuan Jiang,  and Zhi Yao
6734-6745
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SAG/RBX2 is a novel substrate of NEDD4-1 E3 ubiquitin ligase and mediates NEDD4-1 induced chemosensitization

SAG/RBX2 is a novel substrate of NEDD4-1 E3 ubiquitin ligase and mediates NEDD4-1 induced chemosensitization

https://doi.org/10.18632/oncotarget.2246

Weihua Zhou, Jie Xu, Yongchao Zhao,  and Yi Sun
6746-6755
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CPEB1 modulates differentiation of glioma stem cells via downregulation of HES1 and SIRT1 expression

CPEB1 modulates differentiation of glioma stem cells via downregulation of HES1 and SIRT1 expression

https://doi.org/10.18632/oncotarget.2250

Jinlong Yin, Gunwoo Park, Jeong Eun Lee, Ju Young Park, Tae-Hoon Kim, Youn-Jae Kim, Seung-Hoon Lee, Heon Yoo, Jong Heon Kim,  and Jong Bae Park
6756-6769
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The BCL9-2 proto-oncogene governs estrogen receptor alpha expression in breast tumorigenesis

The BCL9-2 proto-oncogene governs estrogen receptor alpha expression in breast tumorigenesis

https://doi.org/10.18632/oncotarget.2252

Nathalie Zatula, Maria Wiese, Jens Bunzendahl, Walter Birchmeier, Christina Perske, Annalen Bleckmann,  and Felix H. Brembeck
6770-6787
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Dual PI3K/mTOR inhibition is required to effectively impair microenvironment survival signals in mantle cell lymphoma

Dual PI3K/mTOR inhibition is required to effectively impair microenvironment survival signals in mantle cell lymphoma

https://doi.org/10.18632/oncotarget.2253

Laia Rosich, Arnau Montraveta, Sílvia Xargay-Torrent, Mónica López-Guerra, Jocabed Roldán, Marta Aymerich, Itziar Salaverria, Sílvia Beà, Elías Campo, Patricia Pérez-Galán, Gaël Roué,  and Dolors Colomer
6788-6800
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AZD1480 delays tumor growth in a melanoma model while enhancing the suppressive activity of myeloid-derived suppressor cells

AZD1480 delays tumor growth in a melanoma model while enhancing the suppressive activity of myeloid-derived suppressor cells

https://doi.org/10.18632/oncotarget.2254

Sarah K. Maenhout, Stephanie Du Four, Jurgen Corthals, Bart Neyns, Kris Thielemans,  and Joeri L. Aerts
6801-6815
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Release of Ca2+ from the endoplasmic reticulum and its subsequent influx into mitochondria trigger celastrol-induced paraptosis in cancer cells

Release of Ca2+ from the endoplasmic reticulum and its subsequent influx into mitochondria trigger celastrol-induced paraptosis in cancer cells

https://doi.org/10.18632/oncotarget.2256

Mi Jin Yoon, A Reum Lee, Soo Ah Jeong, You-Sun Kim, Jin Yeop Kim, Yong-Jun Kwon,  and Kyeong Sook Choi
6816-6831
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IGF2BP3-mediated translation in cell protrusions promotes cell invasiveness and metastasis of pancreatic cancer

IGF2BP3-mediated translation in cell protrusions promotes cell invasiveness and metastasis of pancreatic cancer

https://doi.org/10.18632/oncotarget.2257

Keisuke Taniuchi, Mutsuo Furihata, Kazuhiro Hanazaki, Motoaki Saito,  and Toshiji Saibara
6832-6845
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The anti-apoptotic BAG3 protein is expressed in lung carcinomas and regulates small cell lung carcinoma (SCLC) tumor growth

The anti-apoptotic BAG3 protein is expressed in lung carcinomas and regulates small cell lung carcinoma (SCLC) tumor growth

https://doi.org/10.18632/oncotarget.2261

Gennaro Chiappetta, Anna Basile, Antonio Barbieri, Antonia Falco, Alessandra Rosati, Michelina Festa, Rosa Pasquinelli, Daniela Califano, Giuseppe Palma, Raffaele Costanzo, Daniela Barcaroli, Mario Capunzo, Renato Franco, Gaetano Rocco, Maria Pascale, Maria Caterina Turco, Vincenzo De Laurenzi,  and Claudio Arra
6846-6853
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CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma

CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.2269

Oihana Murillo-Sauca, Man Ki Chung, June Ho Shin, Christina Karamboulas, Shirley Kwok, Young Ho Jung, Richard Oakley, James R. Tysome, Lovisa O. Farnebo, Michael J. Kaplan, Davud Sirjani, Vasu Divi, F. Christopher Holsinger, Chafeek Tomeh, Anthony Nichols, Quynh T. Le, A. Dimitrios Colevas, Christina S. Kong, Ravindra Uppaluri, James S. Lewis Jr, Laurie E. Ailles,  and John B. Sunwoo
6854-6866
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Protein kinase D1 attenuates tumorigenesis in colon cancer by modulating β-catenin/T cell factor activity

Protein kinase D1 attenuates tumorigenesis in colon cancer by modulating β-catenin/T cell factor activity

https://doi.org/10.18632/oncotarget.2277

Vasudha Sundram, Aditya Ganju, Joshua E. Hughes, Sheema Khan, Subhash C. Chauhan,  and Meena Jaggi
6867-6884
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

NOTCH1 signaling contributes to cell growth, anti-apoptosis and metastasis in salivary adenoid cystic carcinoma

NOTCH1 signaling contributes to cell growth, anti-apoptosis and metastasis in salivary adenoid cystic carcinoma

https://doi.org/10.18632/oncotarget.2321

Bo-Hua Su, Jing Qu, Min Song, Xiao-Yu Huang, Xiao-Meng Hu, Jian Xie, Yong Zhao, Lin-Can Ding, Lin She, Jiang Chen, Li-Song Lin, Xu Lin, Da-Li Zheng,  and You-Guang Lu
6885-6895
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The BIRC6 gene as a novel target for therapy of prostate cancer: dual targeting of inhibitors of apoptosis

The BIRC6 gene as a novel target for therapy of prostate cancer: dual targeting of inhibitors of apoptosis

https://doi.org/10.18632/oncotarget.2229

Sze Ue Iris Luk, Hui Xue, Hongwei Cheng, Dong Lin, Peter W. Gout, Ladan Fazli, Colin C. Collins, Martin E. Gleave,  and Yuzhuo Wang
6896-6908
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Transcriptional regulation of the p73 gene by Nrf-2 and promoter CpG methylation in human breast cancer

Transcriptional regulation of the p73 gene by Nrf-2 and promoter CpG methylation in human breast cancer

https://doi.org/10.18632/oncotarget.2230

Jing Lai, Weiwei Nie, Wenwen Zhang, Yucai Wang, Ruilian Xie, Yanru Wang, Jun Gu, Jing Xu, Wei Song, Fang Yang, Guichun Huang, Peng Cao,  and Xiaoxiang Guan
6909-6922
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epigenetic regulations in the IFNγ signalling pathway: IFNγ-mediated MHC class I upregulation on tumour cells is associated with DNA demethylation of antigen-presenting machinery genes

Epigenetic regulations in the IFNγ signalling pathway: IFNγ-mediated MHC class I upregulation on tumour cells is associated with DNA demethylation of antigen-presenting machinery genes

https://doi.org/10.18632/oncotarget.2222

Veronika Vlková, Ivan Štěpánek, Veronika Hrušková, Filip Šenigl, Veronika Mayerová, Martin Šrámek, Jana Šímová, Jana Bieblová, Marie Indrová, Tomáš Hejhal, Nicolas Dérian, David Klatzmann, Adrien Six,  and Milan Reiniš
6923-6935
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tuberin-deficiency downregulates N-cadherin and upregulates vimentin in kidney tumor of TSC patients

Tuberin-deficiency downregulates N-cadherin and upregulates vimentin in kidney tumor of TSC patients

https://doi.org/10.18632/oncotarget.2206

Sitai Liang, Tiffanie Salas, Emre Gencaslan, Baojie Li,  and Samy L. Habib
6936-6946
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A generic cycling hypoxia-derived prognostic gene signature: application to breast cancer profiling

A generic cycling hypoxia-derived prognostic gene signature: application to breast cancer profiling

https://doi.org/10.18632/oncotarget.2285

Romain Boidot, Samuel Branders, Thibault Helleputte, Laila Illan Rubio, Pierre Dupont,  and Olivier Feron
6947-6963
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

USP17 is required for clathrin mediated endocytosis of epidermal growth factor receptor

USP17 is required for clathrin mediated endocytosis of epidermal growth factor receptor

https://doi.org/10.18632/oncotarget.2165

Jakub Jaworski, Michelle de la Vega, Sarah J. Fletcher, Cheryl McFarlane, Michelle K. Greene, Andrew W. Smyth, Sandra Van Schaeybroeck, James A. Johnston, Christopher J. Scott, Joshua Z. Rappoport,  and James F. Burrows
6964-6975
Abstract  |  PDF  |  HTML  |  Order a Reprint

Deletion of Ptprd and Cdkn2a cooperate to accelerate tumorigenesis

Deletion of Ptprd and Cdkn2a cooperate to accelerate tumorigenesis

https://doi.org/10.18632/oncotarget.2106

Berenice Ortiz, Julie R. White, Wei H. Wu,  and Timothy A. Chan
6976-6982
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-497 downregulation contributes to the malignancy of pancreatic cancer and associates with a poor prognosis

MiR-497 downregulation contributes to the malignancy of pancreatic cancer and associates with a poor prognosis

https://doi.org/10.18632/oncotarget.2184

Jianwei Xu, Tianxiao Wang, Zhe Cao, Hua Huang, Jian Li, Wenjing Liu, Shanglong Liu, Lei You, Li Zhou, Taiping Zhang,  and Yupei Zhao
6983-6993
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Development, optimization, and validation of novel anti-TEM1/CD248 affinity agent for optical imaging in cancer

Development, optimization, and validation of novel anti-TEM1/CD248 affinity agent for optical imaging in cancer

https://doi.org/10.18632/oncotarget.2188

Chunsheng Li, Junying Wang, Jia Hu, Yi Feng, Kosei Hasegawa, Xiaohui Peng, Xingmei Duan, Aizhi Zhao, John L. Mikitsh, Vladimir R. Muzykantov, Ann-Marie Chacko, Daniel A. Pryma, Steven M. Dunn,  and George Coukos
6994-7012
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-25 regulates chemoresistance-associated autophagy in breast cancer cells, a process modulated by the natural autophagy inducer isoliquiritigenin

MicroRNA-25 regulates chemoresistance-associated autophagy in breast cancer cells, a process modulated by the natural autophagy inducer isoliquiritigenin

https://doi.org/10.18632/oncotarget.2192

Zhiyu Wang, Neng Wang, Pengxi Liu, Qianjun Chen, Honglin Situ, Ting Xie, Jianxing Zhang, Cheng Peng, Yi Lin,  and Jianping Chen
7013-7026
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The side population of ovarian cancer cells defines a heterogeneous compartment exhibiting stem cell characteristics

The side population of ovarian cancer cells defines a heterogeneous compartment exhibiting stem cell characteristics

https://doi.org/10.18632/oncotarget.2053

Maximilian Boesch, Alain G. Zeimet, Daniel Reimer, Stefan Schmidt, Guenther Gastl, Walther Parson, Franziska Spoeck, Jiri Hatina, Dominik Wolf,  and Sieghart Sopper
7027-7039
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

KIAA1199 interacts with glycogen phosphorylase kinase β-subunit (PHKB) to promote glycogen breakdown and cancer cell survival

KIAA1199 interacts with glycogen phosphorylase kinase β-subunit (PHKB) to promote glycogen breakdown and cancer cell survival

https://doi.org/10.18632/oncotarget.2220

Masato Terashima, Yoshihiko Fujita, Yosuke Togashi, Kazuko Sakai, Marco A. De Velasco, Shuta Tomida,  and Kazuto Nishio
7040-7050
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Critical role of STAT3 in melanoma metastasis through anoikis resistance

Critical role of STAT3 in melanoma metastasis through anoikis resistance

https://doi.org/10.18632/oncotarget.2251

Neel M. Fofaria,  and Sanjay K. Srivastava
7051-7064
Abstract  |  PDF  |  HTML  |  Order a Reprint

Proteasome inhibition reverses hedgehog inhibitor and taxane resistance in ovarian cancer

Proteasome inhibition reverses hedgehog inhibitor and taxane resistance in ovarian cancer

https://doi.org/10.18632/oncotarget.2295

Adam D. Steg, Mata R. Burke, Hope M. Amm, Ashwini A. Katre, Zachary C. Dobbin, Dae Hoon Jeong,  and Charles N. Landen
7065-7080
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Deubiquitinating enzyme Usp12 regulates the interaction between the androgen receptor and the Akt pathway

Deubiquitinating enzyme Usp12 regulates the interaction between the androgen receptor and the Akt pathway

https://doi.org/10.18632/oncotarget.2162

Urszula L. McClurg, Emma E. Summerscales, Victoria J. Harle, Luke Gaughan,  and Craig N. Robson
7081-7092
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De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells

De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells

https://doi.org/10.18632/oncotarget.2197

Yan-hua Ren, Ke-jia Liu, Ming Wang, Ya-nan Yu, Kai Yang, Qin Chen, Bin Yu, Wei Wang, Qi-wei Li, Jian Wang, Zhao-yuan Hou, Jing-yuan Fang, Edward T. Yeh, Jie Yang,  and Jing Yi
7093-7104
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Phosphatidylserine-selective targeting and anticancer effects of SapC-DOPS nanovesicles on brain tumors

Phosphatidylserine-selective targeting and anticancer effects of SapC-DOPS nanovesicles on brain tumors

https://doi.org/10.18632/oncotarget.2214

Víctor M. Blanco, Zhengtao Chu, Subrahmanya D. Vallabhapurapu, Mahaboob K. Sulaiman, Ady Kendler, Olivier Rixe, Ronald E. Warnick, Robert S. Franco,  and Xiaoyang Qi
7105-7118
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Tumor-targeting Salmonella typhimurium A1-R prevents experimental human breast cancer bone metastasis in nude mice

Tumor-targeting Salmonella typhimurium A1-R prevents experimental human breast cancer bone metastasis in nude mice

https://doi.org/10.18632/oncotarget.2226

Shinji Miwa, Shuya Yano, Yong Zhang, Yasunori Matsumoto, Fuminari Uehara, Mako Yamamoto, Yukihiko Hiroshima, Hiroaki Kimura, Katsuhiro Hayashi, Norio Yamamoto, Michael Bouvet, Hiroyuki Tsuchiya, Robert M. Hoffman,  and Ming Zhao
7119-7125
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X-linked inhibitor of apoptosis protein (XIAP) lacking RING domain localizes to the nuclear and promotes cancer cell anchorage-independent growth by targeting the E2F1/Cyclin E axis

X-linked inhibitor of apoptosis protein (XIAP) lacking RING domain localizes to the nuclear and promotes cancer cell anchorage-independent growth by targeting the E2F1/Cyclin E axis

https://doi.org/10.18632/oncotarget.2227

Zipeng Cao, Xueyong Li, Jingxia Li, Wenjing Luo, Chuanshu Huang,  and Jingyuan Chen
7126-7137
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HER3 as biomarker and therapeutic target in pancreatic cancer: new insights in pertuzumab therapy in preclinical models

HER3 as biomarker and therapeutic target in pancreatic cancer: new insights in pertuzumab therapy in preclinical models

https://doi.org/10.18632/oncotarget.2231

Gaëlle Thomas, Thierry Chardès, Nadège Gaborit, Caroline Mollevi, Wilhem Leconet, Bruno Robert, Nina Radosevic-Robin, Frédérique Penault-Llorca, Céline Gongora, Pierre-Emmanuel Colombo, Yassamine Lazrek, Rui Bras-Goncalves, Ariel Savina, David Azria, Hervé Bazin, André Pèlegrin,  and Christel Larbouret
7138-7148
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

In comparative analysis of multi-kinase inhibitors for targeted medulloblastoma therapy pazopanib exhibits promising in vitro and in vivo efficacy

In comparative analysis of multi-kinase inhibitors for targeted medulloblastoma therapy pazopanib exhibits promising in vitro and in vivo efficacy

https://doi.org/10.18632/oncotarget.2240

Rogerio B. Craveiro, Michael Ehrhardt, Martin I. Holst, Thorsten Pietsch,  and Dagmar Dilloo
7149-7161
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Transcribed ultraconserved noncoding RNAs (T-UCR) are involved in Barrett’s esophagus carcinogenesis

Transcribed ultraconserved noncoding RNAs (T-UCR) are involved in Barrett’s esophagus carcinogenesis

https://doi.org/10.18632/oncotarget.2249

Matteo Fassan, Luigi Dall’Olmo, Marco Galasso, Chiara Braconi, Marco Pizzi, Stefano Realdon, Stefano Volinia, Nicola Valeri, Pierluigi Gasparini, Raffaele Baffa, Rhonda F. Souza, Caterina Vicentini, Edoardo D’Angelo, Jan Bornschein, Gerard J. Nuovo, Giovanni Zaninotto, Carlo M. Croce,  and Massimo Rugge
7162-7171
Abstract  |  PDF  |  HTML  |  Order a Reprint

EZH2 dependent H3K27me3 is involved in epigenetic silencing of ID4 in prostate cancer

EZH2 dependent H3K27me3 is involved in epigenetic silencing of ID4 in prostate cancer

https://doi.org/10.18632/oncotarget.2262

Swathi Chinaranagari, Pankaj Sharma,  and Jaideep Chaudhary
7172-7182
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Apollon modulates chemosensitivity in human esophageal squamous cell carcinoma

Apollon modulates chemosensitivity in human esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.2293

Si Zhang, Wenqing Tang, Shuqiang Weng, Xijun Liu, Benqiang Rao, Jianxin Gu, She Chen, Qun Wang, Xizhong Shen, Ruyi Xue,  and Ling Dong
7183-7197
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Mapping of apoptin-interaction with BCR-ABL1, and development of apoptin-based targeted therapy

Mapping of apoptin-interaction with BCR-ABL1, and development of apoptin-based targeted therapy

https://doi.org/10.18632/oncotarget.2278

Jaganmohan R. Jangamreddy, Soumya Panigrahi, Kourosh Lotfi, Manisha Yadav, Subbareddy Maddika, Anil Kumar Tripathi, Sabyasachi Sanyal,  and Marek J. Łos
7198-7211
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