Oncotarget

Vol 5, No 8

April 30, 2014

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Section of the colonies formed in Matrigel from siMock or siRing1B MDA-MB-231 cells, analyzed by Phalloidin staining.See Bosch et al.

Table of Contents

Reviews

Aberrant regulation of FBW7 in cancer

Aberrant regulation of FBW7 in cancer

https://doi.org/10.18632/oncotarget.1859

Lixia Wang, Xiantao Ye, Yueyong Liu, Wenyi Wei,  and Zhiwei Wang
2000-2015
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Epigenetic plasticity: A central regulator of epithelial-to-mesenchymal transition in cancer

Epigenetic plasticity: A central regulator of epithelial-to-mesenchymal transition in cancer

https://doi.org/10.18632/oncotarget.1875

Upasana Bedi, Vivek Kumar Mishra, David Wasilewski, Christina Scheel,  and Steven A. Johnsen
2016-2029
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Priority Research Papers

MDM2 antagonists synergize broadly and robustly with compounds targeting fundamental oncogenic signaling pathways

MDM2 antagonists synergize broadly and robustly with compounds targeting fundamental oncogenic signaling pathways

https://doi.org/10.18632/oncotarget.1918

Anne Y. Saiki, Sean Caenepeel, Dongyin Yu, Julie A. Lofgren, Tao Osgood, Rebecca Robertson, Jude Canon, Cheng Su, Adrie Jones, Xiaoning Zhao, Chetan Deshpande, Marc Payton, Jebediah Ledell, Paul E. Hughes,  and Jonathan D. Oliner
2030-2043
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Research Papers

Polyubiquitylation of AMF requires cooperation between the gp78 and TRIM25 ubiquitin ligases

Polyubiquitylation of AMF requires cooperation between the gp78 and TRIM25 ubiquitin ligases

https://doi.org/10.18632/oncotarget.1478

Ying Wang, Seung-Wook Ha, Tianpeng Zhang, Dhong-Hyo Kho, Avraham Raz,  and Youming Xie
2044-2051
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Indoleamine 2,3-dioxygenase 1 (IDO1) activity in leukemia blasts correlates with poor outcome in childhood acute myeloid leukemia

Indoleamine 2,3-dioxygenase 1 (IDO1) activity in leukemia blasts correlates with poor outcome in childhood acute myeloid leukemia

https://doi.org/10.18632/oncotarget.1504

Valentina Folgiero, Bianca M. Goffredo, Perla Filippini, Riccardo Masetti, Giuseppina Bonanno, Roberta Caruso, Valentina Bertaina, Angela Mastronuzzi, Stefania Gaspari, Marco Zecca, Giovanni F Torelli, Anna M Testi, Andrea Pession, Franco Locatelli,  and Sergio Rutella
2052-2064
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The Polycomb group protein RING1B is overexpressed in ductal breast carcinoma and is required to sustain FAK steady state levels in breast cancer epithelial cells

The Polycomb group protein RING1B is overexpressed in ductal breast carcinoma and is required to sustain FAK steady state levels in breast cancer epithelial cells

https://doi.org/10.18632/oncotarget.1779

Almudena Bosch, Konstantina Panoutsopoulou, Josep Maria Corominas, Ramón Gimeno, Gema Moreno-Bueno, Juan Martín-Caballero, Saleta Morales, Tania Lobato, Carles Martínez-Romero, Eduardo F. Farias, Xavier Mayol, Amparo Cano,  and Inmaculada Hernández-Muñoz
2065-2076
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Galectin-3 induces cell migration via a calcium-sensitive MAPK/ERK1/2 pathway

Galectin-3 induces cell migration via a calcium-sensitive MAPK/ERK1/2 pathway

https://doi.org/10.18632/oncotarget.1786

Xiaoge Gao, Vitaly Balan, Guihua Tai,  and Avraham Raz
2077-2084
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SIRT1 promotes proliferation and inhibits the senescence-like phenotype in human melanoma cells

SIRT1 promotes proliferation and inhibits the senescence-like phenotype in human melanoma cells

https://doi.org/10.18632/oncotarget.1791

Mickaël Ohanna, Caroline Bonet, Karine Bille, Maryline Allegra, Irwin Davidson, Philippe Bahadoran, Jean-Philippe Lacour, Robert Ballotti,  and Corine Bertolotto
2085-2095
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C1GALT1 overexpression promotes the invasive behavior of colon cancer cells through modifying O-glycosylation of FGFR2

C1GALT1 overexpression promotes the invasive behavior of colon cancer cells through modifying O-glycosylation of FGFR2

https://doi.org/10.18632/oncotarget.1815

Ji-Shiang Hung, John Huang, Yo-Chuen Lin, Miao-Juei Huang, Po-Huang Lee, Hong-Shiee Lai, Jin-Tung Liang,  and Min-Chuan Huang
2096-2106
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Mapping of actionable mutations to histological subtype domains in lung adenocarcinoma: implications for precision medicine

Mapping of actionable mutations to histological subtype domains in lung adenocarcinoma: implications for precision medicine

https://doi.org/10.18632/oncotarget.1840

Gavin M. Wright, Hongdo Do, Jonathan Weiss, Naveed Alam, Vivek Rathi, Marzena Walkiewicz, Thomas John, Prudence Russell,  and Alexander Dobrovic
2107-2115
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∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites.

∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites.

https://doi.org/10.18632/oncotarget.1845

Paola Monti, Yari Ciribilli, Alessandra Bisio, Giorgia Foggetti, Ivan Raimondi, Paola Campomenosi, Paola Menichini, Gilberto Fronza,  and Alberto Inga
2116-2130
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Inhibition of protein kinase II (CK2) prevents induced signal transducer and activator of transcription (STAT) 1/3 and constitutive STAT3 activation

Inhibition of protein kinase II (CK2) prevents induced signal transducer and activator of transcription (STAT) 1/3 and constitutive STAT3 activation

https://doi.org/10.18632/oncotarget.1852

Samadhi Aparicio-Siegmund, Jan Sommer, Niloufar Monhasery, Ralf Schwanbeck, Eric Keil, David Finkenstädt, Klaus Pfeffer, Stefan Rose-John, Jürgen Scheller,  and Christoph Garbers
2131-2148
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The EF-hand calcium-binding protein tescalcin is a potential oncotarget in colorectal cancer

The EF-hand calcium-binding protein tescalcin is a potential oncotarget in colorectal cancer

https://doi.org/10.18632/oncotarget.1851

Yun Hee Kang, Seung Ro Han, Jong-Tae Kim, Seon-Jin Lee, Young Il Yeom, Jeong-Ki Min, Chul-Ho Lee, Jae Wha Kim, Suk Ran Yoon, Do-Young Yoon, Kwan Soo Hong, Geum-Sook Hwang, Hee Cheol Kim, Young-Ha Lee,  and Hee Gu Lee
2149-2160
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MiR-214 and N-ras regulatory loop suppresses rhabdomyosarcoma cell growth and xenograft tumorigenesis

MiR-214 and N-ras regulatory loop suppresses rhabdomyosarcoma cell growth and xenograft tumorigenesis

https://doi.org/10.18632/oncotarget.1855

Hui-jie Huang, Jun Liu, Hu Hua, San-en Li, Jin Zhao, Shen Yue, Ting-ting Yu, Yu-cui Jin,  and Steven Y. Cheng
2161-2175
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Novel mechanism of JNK pathway activation by adenoviral E1A

Novel mechanism of JNK pathway activation by adenoviral E1A

https://doi.org/10.18632/oncotarget.1860

Vasily S. Romanov, Anna I. Brichkina, Helen Morrison, Tatiana V. Pospelova, Valery A. Pospelov,  and Peter Herrlich
2176-2186
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Minoxidil may suppress androgen receptor-related functions

Minoxidil may suppress androgen receptor-related functions

https://doi.org/10.18632/oncotarget.1886

Cheng-Lung Hsu, Jai-Shin Liu, An-Chi Lin, Chih-Hsun Yang, Wen-Hung Chung,  and Wen-Guey Wu
2187-2197
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Extracellular activation of Wnt signaling through epigenetic dysregulation of Wnt inhibitory factor-1 (Wif-1) is associated with pathogenesis of adrenocortical tumor

Extracellular activation of Wnt signaling through epigenetic dysregulation of Wnt inhibitory factor-1 (Wif-1) is associated with pathogenesis of adrenocortical tumor

https://doi.org/10.18632/oncotarget.1889

Yozo Mitsui, Hiroaki Yasumoto, Taichi Nagami, Miho Hiraki, Naoko Arichi, Noriyoshi Ishikawa, Asuka Araki, Riruke Maruyama, Yuichiro Tanaka, Rajvir Dahiya,  and Hiroaki Shiina
2198-2207
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Anti-vascular endothelial growth factor therapy-induced glioma invasion is associated with accumulation of Tie2-expressing monocytes

Anti-vascular endothelial growth factor therapy-induced glioma invasion is associated with accumulation of Tie2-expressing monocytes

https://doi.org/10.18632/oncotarget.1893

Konrad Gabrusiewicz, Dan Liu, Nahir Cortes-Santiago, Mohammad B. Hossain, Charles A. Conrad, Kenneth D. Aldape, Gregory N. Fuller, Frank C. Marini, Marta M. Alonso, Miguel Angel Idoate, Mark R. Gilbert, Juan Fueyo,  and Candelaria Gomez-Manzano
2208-2220
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Multi-modality imaging to determine the cellular heterogeneity of nasopharyngeal carcinoma components

Multi-modality imaging to determine the cellular heterogeneity of nasopharyngeal carcinoma components

https://doi.org/10.18632/oncotarget.1894

Weidong Zhang, Yanling Zhang, Shi Ke, Mingjian Lu, Guang Yang, Tao Zhang, Jianjun Han, Zhenyin Liu, Wei Wang, Henry Ran, Chaoxia Zou, Shaofan Hu, Guangtao Lei, Chuanxing Li,  and Fujun Zhang
2221-2229
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A long non-coding RNA signature to improve prognosis prediction of colorectal cancer

A long non-coding RNA signature to improve prognosis prediction of colorectal cancer

https://doi.org/10.18632/oncotarget.1895

Ye Hu, Hao-Yan Chen, Chen-Yang Yu, Jie Xu, Ji-Lin Wang, Jin Qian, Xi Zhang,  and Jing-Yuan Fang
2230-2242
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Aurora-A signaling is activated in advanced stage of squamous cell carcinoma of head and neck cancer and requires osteopontin to stimulate invasive behavior

Aurora-A signaling is activated in advanced stage of squamous cell carcinoma of head and neck cancer and requires osteopontin to stimulate invasive behavior

https://doi.org/10.18632/oncotarget.1896

Chih-Yen Chien, Hsin-Ting Tsai, Li-Jen Su, Hui-Ching Chuang, Li-Yen Shiu, Chao-Cheng Huang, Fu-Min Fang, Chun-Chieh Yu, Huei-Ting Su,  and Chang-Han Chen
2243-2262
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Combinatorial inhibition of Plk1 and PKCβ in cancer cells with different p53 status

Combinatorial inhibition of Plk1 and PKCβ in cancer cells with different p53 status

https://doi.org/10.18632/oncotarget.1897

Lisa Lange, Sarah Keppner-Witter, Juline Grigat,  and Birgit Spänkuch
2263-2275
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Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449a

Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449a

https://doi.org/10.18632/oncotarget.1902

Er-bao Zhang, Rong Kong, Dan-dan Yin, Liang-hui You, Ming Sun, Liang Han, Tong-peng Xu, Rui Xia, Jin-song Yang, Wei De,  and Jin fei Chen
2276-2292
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Multiplex genomic profiling of non–small cell lung cancers from the LETS phase III trial of first-line S-1/carboplatin versus paclitaxel/carboplatin: results of a West Japan Oncology Group study

Multiplex genomic profiling of non–small cell lung cancers from the LETS phase III trial of first-line S-1/carboplatin versus paclitaxel/carboplatin: results of a West Japan Oncology Group study

https://doi.org/10.18632/oncotarget.1906

Isamu Okamoto, Kazuko Sakai, Satoshi Morita, Hiroshige Yoshioka, Hiroyasu Kaneda, Koji Takeda, Tomonori Hirashima, Yoshihito Kogure, Tatsuo Kimura, Toshiaki Takahashi, Shinji Atagi, Takashi Seto, Toshiyuki Sawa, Masashi Yamamoto, Miyako Satouchi, Motoyasu Okuno, Seisuke Nagase, Koichi Takayama, Keisuke Tomii, Tadashi Maeda, Satoshi Oizumi, Shinji Fujii, Yusaku Akashi, Kazumi Nishino, Noriyuki Ebi, Kazuhiko Nakagawa, Yoichi Nakanishi,  and Kazuto Nishio
2293-2304
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Caspase-3 and Caspase-6 cleave STAT1 in leukemic cells

Caspase-3 and Caspase-6 cleave STAT1 in leukemic cells

https://doi.org/10.18632/oncotarget.1911

Verena Licht, Katrin Noack, Bernhard Schlott, Martin Förster, Yvonne Schlenker, Andreas Licht, Oliver H. Krämer,  and Thorsten Heinzel
2305-2317
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Overexpression of lncRNA H19 enhances carcinogenesis and metastasis of gastric cancer

Overexpression of lncRNA H19 enhances carcinogenesis and metastasis of gastric cancer

https://doi.org/10.18632/oncotarget.1913

Hao Li, Beiqin Yu, Jianfang Li, Liping Su, Min Yan, Zhenggang Zhu,  and Bingya Liu
2318-2329
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CUL4A contributes to the biology of basal-like breast tumors through modulation of cell growth and antitumor immune response

CUL4A contributes to the biology of basal-like breast tumors through modulation of cell growth and antitumor immune response

https://doi.org/10.18632/oncotarget.1915

Laura P. Saucedo-Cuevas, Isabel Ruppen, Pilar Ximénez-Embún, Samuel Domingo, Javier Gayarre, Javier Muñoz, Jose M. Silva, María J. García,  and Javier Benítez
2330-2343
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