Oncotarget

Vol 5, No 4

February 28, 2014

View Archive »

Order a Reprint

About The Cover

H&E of the wild type Pten+/- gallbladders. See Lunardi et al.

Table of Contents

Reviews

Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instability

Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instability

https://doi.org/10.18632/oncotarget.1784

Tae-Hyung Kim, Patrick Leslie,  and Yanping Zhang
860-871
Abstract  |  PDF  |  HTML  |  Order a Reprint

miR-34: from bench to bedside

miR-34: from bench to bedside

https://doi.org/10.18632/oncotarget.1825

Massimiliano Agostini,  and Richard A. Knight
872-881
Abstract  |  PDF  |  HTML  |  Order a Reprint

Priority Research Papers

Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma

Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma

https://doi.org/10.18632/oncotarget.1801

Jie Li, Shan Zhu, David Kozono, Kimberly Ng, Diahnn Futalan, Ying Shen, Johnny C. Akers, Tyler Steed, Deepa Kushwaha, Michael Schlabach, Bob S. Carter, Chang-Hyuk Kwon, Frank Furnari, Webster Cavenee, Stephen Elledge,  and Clark C. Chen
882-893
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Role of aberrant PI3K pathway activation in gallbladder tumorigenesis

Role of aberrant PI3K pathway activation in gallbladder tumorigenesis

https://doi.org/10.18632/oncotarget.1808

Andrea Lunardi, Kaitlyn A. Webster, Antonella Papa, Bhavik Padmani, John G. Clohessy, Roderick T. Bronson,  and Pier Paolo Pandolfi
894-900
Abstract  |  PDF  |  HTML  |  Order a Reprint

A novel peptide that inhibits E2F transcription and regresses prostate tumor xenografts

A novel peptide that inhibits E2F transcription and regresses prostate tumor xenografts

https://doi.org/10.18632/oncotarget.1809

Xiaoqi Xie, Nitu Bansal, Tazeem Shaik, John E. Kerrigan, Tamara Minko, Olga Garbuzenko, Emine Ercikan Abali, Nadine Johnson-Farley, Debabrata Banerjee, Kathleen W. Scotto,  and Joseph R. Bertino
901-907
Abstract  |  PDF  |  HTML  |  Order a Reprint

Research Papers

A potential therapeutic strategy for chronic lymphocytic leukemia by combining Idelalisib and GS-9973, a novel spleen tyrosine kinase (Syk) inhibitor

A potential therapeutic strategy for chronic lymphocytic leukemia by combining Idelalisib and GS-9973, a novel spleen tyrosine kinase (Syk) inhibitor

https://doi.org/10.18632/oncotarget.1484

Russell T Burke, Marc M Loriaux, Kevin S Currie, Scott A Mitchell, Patricia Maciejewski, Astrid S Clarke, Julie A DiPaolo, Brian J Druker, Stephen E Spurgeon,  and Brian J Lannutti
908-915
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: Results of the ALFA-0701 trial

Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: Results of the ALFA-0701 trial

https://doi.org/10.18632/oncotarget.1536

Aline Renneville, Raouf Ben Abdelali, Sylvie Chevret, Olivier Nibourel, Meyling Cheok, Cecile Pautas, Remy Dulery, Thomas Boyer, Jean-Michel Cayuela, Sandrine Hayette, Emmanuel Raffoux, Hassan Farhat, Nicolas Boissel, Christine Terre, Herve Dombret, Sylvie Castaigne,  and Claude Preudhomme
916-932
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High Mdm4 levels suppress p53 activity and enhance its half-life in acute myeloid leukaemia

High Mdm4 levels suppress p53 activity and enhance its half-life in acute myeloid leukaemia

https://doi.org/10.18632/oncotarget.1559

Ban Xiong Tan, Kian Hoe Khoo, Tit Meng Lim,  and David Philip Lane
933-943
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer

Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer

https://doi.org/10.18632/oncotarget.1458

Michelle X. Liu, Michelle KY. Siu, Stephanie S. Liu, Judy WP. Yam, Hextan YS. Ngan,  and David W. Chan
944-958
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Engineered repressors are potent inhibitors of androgen receptor activity

Engineered repressors are potent inhibitors of androgen receptor activity

https://doi.org/10.18632/oncotarget.1360

Greg N. Brooke, Sue M. Powell, Derek N. Lavery, Jonathan Waxman, Laki Buluwela, Simak Ali,  and Charlotte L. Bevan
959-969
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LZTS1 downregulation confers paclitaxel resistance and is associated with worse prognosis in breast cancer

LZTS1 downregulation confers paclitaxel resistance and is associated with worse prognosis in breast cancer

https://doi.org/10.18632/oncotarget.1630

Francesca Lovat, Hideshi Ishii, Monica Schiappacassi, Matteo Fassan, Mattia Barbareschi, Enzo Galligioni, Pierluigi Gasparini, Gustavo Baldassarre, Carlo M. Croce,  and Andrea Vecchione
970-977
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

WNT-pathway components as predictive markers useful for diagnosis, prevention and therapy in inflammatory bowel disease and sporadic colorectal cancer

WNT-pathway components as predictive markers useful for diagnosis, prevention and therapy in inflammatory bowel disease and sporadic colorectal cancer

https://doi.org/10.18632/oncotarget.1571

Annalucia Serafino, Noemi Moroni, Manuela Zonfrillo, Federica Andreola, Luana Mercuri, Giuseppe Nicotera, Joseph Nunziata, Riccardo Ricci, Armando Antinori, Guido Rasi,  and Pasquale Pierimarchi
978-992
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Post-transcriptional regulation of MRE11 expression in muscle-invasive bladder tumours

Post-transcriptional regulation of MRE11 expression in muscle-invasive bladder tumours

https://doi.org/10.18632/oncotarget.1627

Rebecca M. Martin, Martin Kerr, Mark T.W. Teo, Sarah J. Jevons, Marianne Koritzinsky, Bradly G. Wouters, Selina Bhattarai,  and Anne E. Kiltie
993-1003
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth

Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth

https://doi.org/10.18632/oncotarget.1681

David Vindrieux, Guillaume Devailly, Arnaud Augert, Benjamin Le Calve, Mylene Ferrand, Pascal Pigny, Lea Payen, Gerard Lambeau, Michael Perrais, Sebastien Aubert, Hélène Simonnet, Robert Dante,  and David Bernard
1004-1013
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity

https://doi.org/10.18632/oncotarget.1629

Jakob H. Mikkelsen, Zachary T. Resch, Bhanu Kalra, Gopal Savjani, Ajay Kumar, Cheryl A. Conover,  and Claus Oxvig
1014-1025
Abstract  |  PDF  |  HTML  |  Order a Reprint

SCFβ-TRCP-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway

SCFβ-TRCP-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway

https://doi.org/10.18632/oncotarget.1675

Jia Liu, Lixin Wan, Pengda Liu, Hiroyuki Inuzuka, Jiankang Liu, Zhiwei Wang,  and Wenyi Wei
1026-1037
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR

https://doi.org/10.18632/oncotarget.1637

Ulrike M. Litzenburger, Christiane A. Opitz, Felix Sahm, Katharina J. Rauschenbach, Saskia Trump, Marcus Winter, Martina Ott, Katharina Ochs, Christian Lutz, Xiangdong Liu, Natasa Anastasov, Irina Lehmann, Thomas Höfer, Andreas von Deimling, Wolfgang Wick,  and Michael Platten
1038-1051
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene

Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene

https://doi.org/10.18632/oncotarget.1697

Erling A. Hoivik, Kanthida Kusonmano, Mari K. Halle, Anna Berg, Elisabeth Wik, Henrica M. J. Werner, Kjell Petersen, Anne M. Oyan, Karl-Henning Kalland, Camilla Krakstad, Jone Trovik, Martin Widschwendter,  and Helga B. Salvesen
1052-1061
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Rapamycin downregulates thymidylate synthase and potentiates the activity of pemetrexed in non-small cell lung cancer

Rapamycin downregulates thymidylate synthase and potentiates the activity of pemetrexed in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.1760

Shigeru Kawabata, Chun-Te Chiang, Junji Tsurutani, Hideaki Shiga, Matthew L. Arwood, Takefumi Komiya, Joell J. Gills, Regan M. Memmott,  and Phillip A. Dennis
1062-1070
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SENP5 mediates breast cancer invasion via a TGFβRI SUMOylation cascade

SENP5 mediates breast cancer invasion via a TGFβRI SUMOylation cascade

https://doi.org/10.18632/oncotarget.1783

Rivki Cashman, Helit Cohen, Rotem Ben-Hamo, Alona Zilberberg,  and Sol Efroni
1071-1082
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1

miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1

https://doi.org/10.18632/oncotarget.1804

Zuoren Yu, Zengguang Xu, Gabriele DiSante, Jennifer Wright, Min Wang, Yuan Li, Qian Zhao, Tao Ren, Xiaoming Ju, Ellen Gutman, Guangxue Wang, Sankar Addya, Tieyan Li, Zhendong Xiang, Chenguang Wang, Xiongfei Yang, Xiaolai Yang,  and Richard Pestell
1083-1090
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HCMV glycoprotein B is expressed in primary glioblastomas and enhances growth and invasiveness via PDGFR-alpha activation

HCMV glycoprotein B is expressed in primary glioblastomas and enhances growth and invasiveness via PDGFR-alpha activation

https://doi.org/10.18632/oncotarget.1787

Charles Cobbs, Sabeena Khan, Lisa Matlaf, Sean McAllister, Alex Zider, Garret Yount, Kenneth Rahlin, Lualhati Harkins, Vladimir Bezrookove, Eric Singer,  and Liliana Soroceanu
1091-1100
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivity

Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivity

https://doi.org/10.18632/oncotarget.1795

Kelly K. Haagenson, Jessica Wei Zhang, Zhengfan Xu, Malathy P.V. Shekhar,  and Gen Sheng Wu
1101-1110
Abstract  |  PDF  |  HTML  |  Order a Reprint


Copyright © 2017 Impact Journals
Impact Journals is a registered trademark of Impact Journals, LLC