Oncotarget

Vol 5, No 2

January 30, 2014

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About The Cover



The cover of Oncotarget features figure 6 from Mochmann et al. Shown are argarose smears of ERG-induced cells stained with DAPI in the presence of Ara-C.

Table of Contents

Reviews

Apoptosis inducers in chronic lymphocytic leukemia

Apoptosis inducers in chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.1480

Christian Billard
309-325
Abstract  |  PDF  |  HTML  |  Order a Reprint

Research Papers

Antitumor activity of the c-Myc inhibitor KSI-3716 in gemcitabine-resistant bladder cancer

Antitumor activity of the c-Myc inhibitor KSI-3716 in gemcitabine-resistant bladder cancer

https://doi.org/10.18632/oncotarget.1545

Ho Kyung Seo, Kyung-Ohk Ahn, Nae-Rae Jung, Ji-Sun Shin, Weon Seo Park, Kang-Hyun Lee, Sang-Jin Lee,  and Kyung-Chae Jeong
326-337
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Pharmacokinetic modeling optimizes inhibition of the ‘undruggable’ EWS-FLI1 transcription factor in Ewing Sarcoma

Pharmacokinetic modeling optimizes inhibition of the ‘undruggable’ EWS-FLI1 transcription factor in Ewing Sarcoma

https://doi.org/10.18632/oncotarget.1495

Sung-Hyeok Hong, Sarah E. Youbi, S. Peter Hong, Bhaskar Kallakury, Phillip Monroe, Hayriye V. Erkizan, Julie S. Barber-Rotenberg, Peter Houghton, Aykut Üren,  and Jeffrey A. Toretsky
338-350
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ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells

ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells

https://doi.org/10.18632/oncotarget.1449

Liliana H. Mochmann, Martin Neumann, Eva K. von Der Heide, Verena Nowak, Anja A. Kühl, Jutta Ortiz-Tanchez, Juliane Bock, Wolf K Hofmann,  and Claudia D Baldus
351-362
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EFEMP1 induces γ-secretase/Notch-mediated temozolomide resistance in glioblastoma

EFEMP1 induces γ-secretase/Notch-mediated temozolomide resistance in glioblastoma

https://doi.org/10.18632/oncotarget.1620

Lotte Hiddingh, Bakhos A. Tannous, Jian Teng, Bas Tops, Judith Jeuken, Esther Hulleman, Sandra H. Boots-Sprenger, W. Peter Vandertop, David P. Noske, Gertjan J.L. Kaspers, Pieter Wesseling,  and Thomas Wurdinger
363-374
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A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine

A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine

https://doi.org/10.18632/oncotarget.1568

Elisabeth Walsby, Guy Pratt, Hao Shao, Abdullah Y. Abbas, Peter M. Fischer, Tracey D. Bradshaw, Paul Brennan, Chris Fegan, Shudong Wang,  and Chris Pepper
375-385
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CITED1 confers stemness to Wilms tumor and enhances tumorigenic responses when enriched in the nucleus

CITED1 confers stemness to Wilms tumor and enhances tumorigenic responses when enriched in the nucleus

https://doi.org/10.18632/oncotarget.1566

Andrew J. Murphy, Janene Pierce, Christian de Caestecker, Gregory D. Ayers, Alex Zhao, Jonathan R. Krebs, Vincente Kenyi Saito-Diaz, Ethan Lee, Alan O. Perantoni, Mark P. de Caestecker,  and Harold N. Lovvorn, III
386-402
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Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing

Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing

https://doi.org/10.18632/oncotarget.1719

Sofia R. Gameiro, Momodou L. Jammeh, Max M. Wattenberg, Kwong Y. Tsang, Soldano Ferrone,  and James W. Hodge
403-416
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Preferred binding of gain-of-function mutant p53 to bidirectional promoters with coordinated binding of ETS1 and GABPA to multiple binding sites

Preferred binding of gain-of-function mutant p53 to bidirectional promoters with coordinated binding of ETS1 and GABPA to multiple binding sites

https://doi.org/10.18632/oncotarget.1708

Catherine A. Vaughan, Swati P. Deb, Sumitra Deb,  and Brad Windle
417-427
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Minor grove binding ligands disrupt PARP-1 activation pathways

Minor grove binding ligands disrupt PARP-1 activation pathways

https://doi.org/10.18632/oncotarget.1742

Kirill Kirsanov, Elena Kotova, Petr Makhov, Konstantin Golovine, Ekaterina A. Lesovaya, Vladimir M. Kolenko, Marianna G. Yakubovskaya,  and Alexei V. Tulin
428-437
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RB1 gene inactivation by chromothripsis in human retinoblastoma

RB1 gene inactivation by chromothripsis in human retinoblastoma

https://doi.org/10.18632/oncotarget.1686

Justina McEvoy, Panduka Nagahawatte, David Finkelstein, Jennifer Richards-Yutz, Marcus Valentine, Jing Ma, Charles Mullighan, Guangchun Song, Xiang Chen, Matthew Wilson, Rachel Brennan, Stanely Pounds, Jared Becksfort, Robert Huether, Charles Lu, Robert S. Fulton, Lucinda L. Fulton, Xin Hong, David J. Dooling, Kerri Ochoa, Elaine R. Mardis, Richard K. Wilson, John Easton, Jinghui Zhang, James R. Downing, Arupa Ganguly,  and Michael A. Dyer
438-450
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GATA2 as a potential metastasis-driving gene in prostate cancer

GATA2 as a potential metastasis-driving gene in prostate cancer

https://doi.org/10.18632/oncotarget.1296

Yan Ting Chiang, Kendric Wang, Ladan Fazli, Robert Z. Qi, Martin E. Gleave, Colin C. Collins, Peter W. Gout,  and Yuzhuo Wang
451-461
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Role of miR-34a as a suppressor of L1CAM in endometrial carcinoma

Role of miR-34a as a suppressor of L1CAM in endometrial carcinoma

https://doi.org/10.18632/oncotarget.1552

Uwe Schirmer, Kai Doberstein, Anne-Kathleen Rupp, Niko P. Bretz, Daniela Wuttig, Helena Kiefel, Christian Breunig, Heidi Fiegl, Elisabeth Müller-Holzner, Robert Zeillinger, Eva Schuster, Alain G. Zeimet, Holger Sültmann,  and Peter Altevogt
462-472
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Neutrophil elastase as a diagnostic marker and therapeutic target in colorectal cancers

Neutrophil elastase as a diagnostic marker and therapeutic target in colorectal cancers

https://doi.org/10.18632/oncotarget.1631

Ai-Sheng Ho, Chien-Hsin Chen, Chun-Chia Cheng, Chia-Chi Wang, Hua-Ching Lin, Tsai-Yueh Luo, Gi-Shih Lien,  and Jungshan Chang
473-480
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Elevated Pentraxin 3 in bone metastatic breast cancer is correlated with osteolytic function

Elevated Pentraxin 3 in bone metastatic breast cancer is correlated with osteolytic function

https://doi.org/10.18632/oncotarget.1664

Bongkun Choi, Eun-Jin Lee, Da-Hyun Song, Sung-Chul Yoon, Yeon-Ho Chung, Yongsaeng Jang, Sang-Min Kim, Youngsup Song, Sang-Wook Kang, Seung-Yong Yoon,  and Eun-Ju Chang
481-492
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NF-κB1 inhibits c-Myc protein degradation through suppression of FBW7 expression

NF-κB1 inhibits c-Myc protein degradation through suppression of FBW7 expression

https://doi.org/10.18632/oncotarget.1643

Haishan Huang, Li Ma, Jingxia Li, Yonghui Yu, Dongyun Zhang, Jinlong Wei, Honglei Jin, Derek Xu, Jinmin Gao,  and Chuanshu Huang
493-505
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Quantitative proteomic analysis reveals potential diagnostic markers and pathways involved in pathogenesis of renal cell carcinoma

Quantitative proteomic analysis reveals potential diagnostic markers and pathways involved in pathogenesis of renal cell carcinoma

https://doi.org/10.18632/oncotarget.1529

Nicole M.A. White, Olena Masui, Leroi V. DeSouza, Olga Krakovska, Shereen Metias, Alexander D. Romaschin, R.John Honey, Robert Stewart, Kenneth Pace, Jason Lee, Michael AS. Jewett, Georg A. Bjarnason, K.W.Michael Siu,  and George M. Yousef
506-518
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Collagen triple helix repeat containing 1 (CTHRC1) acts via ERK-dependent induction of MMP9 to promote invasion of colorectal cancer cells

Collagen triple helix repeat containing 1 (CTHRC1) acts via ERK-dependent induction of MMP9 to promote invasion of colorectal cancer cells

https://doi.org/10.18632/oncotarget.1714

Hee Cheol Kim, Yong Sung Kim, Hyun-Woo Oh, Kwoneel Kim, Sang-Seok Oh, Jong-Tae Kim, Bo Yeon Kim, Seon-Jin Lee, Yong-Kyung Choe, Dong Hyeok Kim, Seok-Hyung Kim, Seoung Wan Chae, Kwang Dong Kim,  and Hee Gu Lee
519-529
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First Mnks degrading agents block phosphorylation of eIF4E, induce apoptosis, inhibit cell growth, migration and invasion in triple negative and Her2-overexpressing breast cancer cell lines

First Mnks degrading agents block phosphorylation of eIF4E, induce apoptosis, inhibit cell growth, migration and invasion in triple negative and Her2-overexpressing breast cancer cell lines

https://doi.org/10.18632/oncotarget.1528

Senthilmurugan Ramalingam, Lalji Gediya, Andrew K. Kwegyir-Afful, Vidya P. Ramamurthy, Puranik Purushottamachar, Hannah Mbatia,  and Vincent C.O. Njar
530-543
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Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation

https://doi.org/10.18632/oncotarget.1652

Zhi-Qiang Wang, Magdalena Bachvarova, Chantale Morin, Marie Plante, Jean Gregoire, Marie-Claude Renaud, Alexandra Sebastianelli,  and Dimcho Bachvarov
544-560
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HIF-1α downregulation and apoptosis in hypoxic prostate tumor cells infected with oncolytic Mammalian Orthoreovirus

HIF-1α downregulation and apoptosis in hypoxic prostate tumor cells infected with oncolytic Mammalian Orthoreovirus

https://doi.org/10.18632/oncotarget.1767

Pooja Gupta-Saraf,  and Cathy L. Miller
561-574
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