Oncotarget

Vol 4, No 4

April 2013

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The anti-tumor agent trabectedin has direct effects on tumor cells, blocking cell cycle and proliferation. See editorial by D’Incalci et al.

Table of Contents

Broadcast

NRAS mutant melanoma – undrugable?

NRAS mutant melanoma – undrugable?

https://doi.org/10.18632/oncotarget.970

Christian Posch,  and Susana Ortiz-Urda
494-495
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Editorial: Oncotarget Editorials

New activities for the anti-tumor agent trabectedin: taking two birds with one stone

New activities for the anti-tumor agent trabectedin: taking two birds with one stone

https://doi.org/10.18632/oncotarget.968

Maurizio D’Incalci, Roberta Frapolli, Giovanni Germano,  and Paola Allavena
496-497
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Regulation of mechanical stress by mammary epithelial tissue structure controls breast cancer cell invasion

Regulation of mechanical stress by mammary epithelial tissue structure controls breast cancer cell invasion

https://doi.org/10.18632/oncotarget.979

Derek C Radisky,  and Celeste M Nelson
498-499
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Jak2V617F myeloproliferative neoplasm stem cells and interferon-alpha.

Jak2V617F myeloproliferative neoplasm stem cells and interferon-alpha.

https://doi.org/10.18632/oncotarget.986

Steven W Lane,  and Ann Mullally
500-501
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Reviews

A conceptually new treatment approach for relapsed glioblastoma: Coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care.

A conceptually new treatment approach for relapsed glioblastoma: Coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care.

https://doi.org/10.18632/oncotarget.969

Richard E. Kast, John A. Boockvar, Ansgar Brüning, Francesco Cappello, Wen-Wei Chang, Boris Cvek, Q Ping Dou, Alfonso Duenas-Gonzalez, Thomas Efferth, Daniele Focosi, Seyed H. Ghaffari, Georg Karpel-Massler, Kirsi Ketola, Alireza Khoshnevisan, Daniel Keizman, Nicolas Magné, Christine Marosi, Kerrie McDonald, Miguel Muñoz, Ameya Paranjpe, Mohammad H. Pourgholami, Iacopo Sardi, Avishay Sella, Kalkunte S. Srivenugopal, Marco Tuccori, Weiguang Wang, Christian R. Wirtz,  and Marc-Eric Halatsch
502-530
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Research Papers

Effects of CT-Xp Gene Knock down in Melanoma Cell Lines

Effects of CT-Xp Gene Knock down in Melanoma Cell Lines

https://doi.org/10.18632/oncotarget.921

Otavia Luisa Caballero, Tzeela Cohen, Sita Gurung, Ramon Chua, Peishan Lee, Yao-Tseng Chen, Parmjit Jat, Lloyd J. Old,  and Andrew J. G. Simpson
531-541
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Galectin-3: a possible complementary marker to the PSA blood test

Galectin-3: a possible complementary marker to the PSA blood test

https://doi.org/10.18632/oncotarget.923

Vitaly Balan, Yi Wang, Pratima Nangia-Makker, Dhonghyo Kho, Madhuri Bajaj, Daryn Smith, Lance Heilbrun, Avraham Raz,  and Elisabeth Heath
542-549
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Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition Up-regulates Interleukin-6 in Cancer Cells and Induces Subsequent Development of Interstitial Pneumonia

Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition Up-regulates Interleukin-6 in Cancer Cells and Induces Subsequent Development of Interstitial Pneumonia

https://doi.org/10.18632/oncotarget.939

Yukari Ishiguro, Hitoshi Ishiguro,  and Hiroshi Miyamoto
550-559
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Characterizing the convergence of protein kinase CK2 and caspase-3 reveals isoform-specific phosphorylation of caspase-3 by CK2α′: implications for pathological roles of CK2 in promoting cancer cell survival.

Characterizing the convergence of protein kinase CK2 and caspase-3 reveals isoform-specific phosphorylation of caspase-3 by CK2α′: implications for pathological roles of CK2 in promoting cancer cell survival.

https://doi.org/10.18632/oncotarget.948

Jacob P Turowec, Greg Vilk, Michelle Gabriel,  and David W Litchfield
560-571
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Exomic Sequencing of Four Rare Central Nervous System Tumor Types

Exomic Sequencing of Four Rare Central Nervous System Tumor Types

https://doi.org/10.18632/oncotarget.964

Chetan Bettegowda, Nishant Agrawal, Yuchen Jiao, Yuxuan Wang, Laura D. Wood, Fausto J. Rodriguez, Ralph H. Hruban, Gary L. Gallia, Zev A. Binder, Callen J. Riggins, Vafi Salmasi, Gregory J. Riggins, Zachary J. Reitman, Ahmed Rasheed, Stephen Keir, Sueli Shinjo, Suely Marie, Roger McLendon, George Jallo, Bert Vogelstein, Darrell Bigner, Hai Yan, Kenneth W. Kinzler,  and Nickolas Papadopoulos
572-583
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Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the V600EBRAF oncogene

Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the V600EBRAF oncogene

https://doi.org/10.18632/oncotarget.965

Arnaldur Hall, Kathrine Damm Meyle, Marina Krarup Lange, Martin Klima, May Sanderhoff, Christina Dahl, Cecilie Abildgaard, Katrine Thorup, Seyed Moein Moghimi, Per Bo Jensen, Jiri Bartek, Per Guldberg,  and Claus Christensen
584-599
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Impact of a genomic classifier of metastatic risk on postoperative treatment recommendations for prostate cancer patients: a report from the DECIDE study group

Impact of a genomic classifier of metastatic risk on postoperative treatment recommendations for prostate cancer patients: a report from the DECIDE study group

https://doi.org/10.18632/oncotarget.918

Ketan Badani, Darby J.S. Thompson, Christine Buerki, Elai Davicioni, Jill Garrison, Mercedeh Ghadessi, Anirban P. Mitra, Penelope J. Wood,  and John Hornberger
600-609
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Prostate derived Ets transcription factor and Carcinoembryonic antigen related cell adhesion molecule 6 constitute a highly active oncogenic axis in breast cancer

Prostate derived Ets transcription factor and Carcinoembryonic antigen related cell adhesion molecule 6 constitute a highly active oncogenic axis in breast cancer

https://doi.org/10.18632/oncotarget.934

Alka Mukhopadhyay, Thaer Khoury, Leighton Stein, Protul Shrikant,  and Ashwani K. Sood
610-621
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Combinatorial drug screening identifies compensatory pathway interactions and adaptive resistance mechanisms

Combinatorial drug screening identifies compensatory pathway interactions and adaptive resistance mechanisms

https://doi.org/10.18632/oncotarget.938

Mark J Axelrod, Vicki Gordon, Mark Conaway, Adel Tarcsafalvi, Daniel J Neitzke, Daniel Gioeli,  and Michael J Weber
622-635
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Expression of Cancer/Testis Antigens is Correlated with Improved Survival in Glioblastoma

Expression of Cancer/Testis Antigens is Correlated with Improved Survival in Glioblastoma

https://doi.org/10.18632/oncotarget.950

Marcelo R.P. Freitas, Suzana M.F. Malheiros, João N. Stávale, Thaís P. Biassi, Fernando T. Zamunér, Maria D.F.S. Begnami, Fernado A. Soares,  and André L. Vettore
636-646
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