Oncotarget

Vol 4, No 2

February 2013

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About The Cover

Crystal structure of the nSH2 and iSH2 of p85 with the p110α catalytic subunit. See Burke, Perisic, Williams.

Table of Contents

Editorial

Deregulation of the CDX2-KLF4 axis in acute myeloid leukemia and colon cancer

Deregulation of the CDX2-KLF4 axis in acute myeloid leukemia and colon cancer

https://doi.org/10.18632/oncotarget.896

Arefeh Rouhi,  and Stefan Fröhling
174-175
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Unexpected Outcomes of CDK4/6 Inhibition

Unexpected Outcomes of CDK4/6 Inhibition

https://doi.org/10.18632/oncotarget.912

Yoon Jong Choi,  and Piotr Sicinski
176-177
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Signaling networks, network pathology and computational chemotherapy

Signaling networks, network pathology and computational chemotherapy

https://doi.org/10.18632/oncotarget.911

Kwang-Hyun Cho
178-179
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Allosteric activation of PI3Kα by oncogenic mutations

Allosteric activation of PI3Kα by oncogenic mutations

https://doi.org/10.18632/oncotarget.913

John E Burke, Olga Perisic,  and Roger L Williams
180-181
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Microbial Oncotarget: Bacterial-Produced Butyrate, Chemoprevention and Warburg Effect

Microbial Oncotarget: Bacterial-Produced Butyrate, Chemoprevention and Warburg Effect

https://doi.org/10.18632/oncotarget.915

Dallas R. Donohoe, Kaitlin P. Curry,  and Scott J. Bultman
182-183
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Research Papers

Calcein-effluxing human colon cancer cells are enriched for self-renewal capacity and depend on β-catenin

Calcein-effluxing human colon cancer cells are enriched for self-renewal capacity and depend on β-catenin

https://doi.org/10.18632/oncotarget.883

Joshua E. Allen,  and Wafik S. El-Deiry
184-191
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HPV16 E5 and KGFR/FGFR2b interplay in differentiating epithelial cells

HPV16 E5 and KGFR/FGFR2b interplay in differentiating epithelial cells

https://doi.org/10.18632/oncotarget.803

Valeria Purpura, Francesca Belleudi, Silvia Caputo,  and Maria Rosaria Torrisi
192-205
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TRAIL induces apoptosis in oral squamous carcinoma cells: a crosstalk with oncogenic Ras regulated cell surface expression of death receptor 5

TRAIL induces apoptosis in oral squamous carcinoma cells: a crosstalk with oncogenic Ras regulated cell surface expression of death receptor 5

https://doi.org/10.18632/oncotarget.813

Jun-jie Chen, Constantinos M. Mikelis, Yaqin Zhang, J. Silvio Gutkind,  and Baolin Zhang
206-217
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Targeted alpha-therapy using [Bi-213]anti-CD20 as novel treatment option for radio- and chemoresistant non-Hodgkin lymphoma cells

Targeted alpha-therapy using [Bi-213]anti-CD20 as novel treatment option for radio- and chemoresistant non-Hodgkin lymphoma cells

https://doi.org/10.18632/oncotarget.817

Mareike Roscher, Inis Hormann, Oliver Leib, Sebastian Marx, Josue Moreno, Erich Miltner,  and Claudia Friesen
218-230
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Comedo-DCIS is a precursor lesion for basal-like breast carcinoma: identification of a novel p63/Her2/neu expressing subgroup

Comedo-DCIS is a precursor lesion for basal-like breast carcinoma: identification of a novel p63/Her2/neu expressing subgroup

https://doi.org/10.18632/oncotarget.818

Malathy PV Shekhar, Ikuko Kato, Pratima Nangia-Makker,  and Larry Tait
231-241
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In Vitro and in Vivo Anti-tumor Activity of miR-221/222 Inhibitors in Multiple Myeloma

In Vitro and in Vivo Anti-tumor Activity of miR-221/222 Inhibitors in Multiple Myeloma

https://doi.org/10.18632/oncotarget.820

Maria Teresa Di Martino, Annamaria Gullà, Maria Eugenia Gallo Cantafio, Marta Lionetti, Emanuela Leone, Nicola Amodio, Pietro Hiram Guzzi, Umberto Foresta, Francesco Conforti, Mario Cannataro, Antonino Neri, Antonio Giordano, Pierosandro Tagliaferri,  and Pierfrancesco Tassone
242-255
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Ras inhibition boosts galectin-7 at the expense of galectin-1 to sensitize cells to apoptosis

Ras inhibition boosts galectin-7 at the expense of galectin-1 to sensitize cells to apoptosis

https://doi.org/10.18632/oncotarget.844

Batya Barkan, Adrienne D. Cox,  and Yoel Kloog
256-268
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Preclinical analyses of intravesical chemotherapy for prevention of bladder cancer progression

Preclinical analyses of intravesical chemotherapy for prevention of bladder cancer progression

https://doi.org/10.18632/oncotarget.852

Joan C Delto, Takashi Kobayashi, Mitchell C Benson, James McKiernan,  and Cory Abate-Shen
269-276
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Efemp1 and p27Kip1 modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models

Efemp1 and p27Kip1 modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models

https://doi.org/10.18632/oncotarget.859

Diersch Sandra, Patrick Wenzel, Melanie Szameitat, Philipp Eser, Mariel C Paul, Barbara Seidler, Stefan Eser, Marlena Messer, Maximilian Reichert, Philipp Pagel, Irene Esposito, Roland M Schmid, Dieter Saur,  and Günter Schneider
277-288
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TAp73β-mediated suppression of cell migration requires p57Kip2 control of actin cytoskeleton dynamics

TAp73β-mediated suppression of cell migration requires p57Kip2 control of actin cytoskeleton dynamics

https://doi.org/10.18632/oncotarget.833

Johanna Rodhe, Edel Kavanagh,  and Bertrand Joseph
289-297
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DNA-intercalators Causing Rapid Re-expression of Methylated and Silenced Genes in Cancer Cells

DNA-intercalators Causing Rapid Re-expression of Methylated and Silenced Genes in Cancer Cells

https://doi.org/10.18632/oncotarget.863

M. Zulfiquer Hossain, Megan A. Healey, Calvin Lee, Weijie Poh, Sashidhar R. Yerram, Kalpesh Patel, Nilofer S. Azad, James G. Herman,  and Scott E. Kern
298-309
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BRAF Mutant Gastrointestinal Stromal Tumor: First report of regression with BRAF inhibitor dabrafenib (GSK2118436) and whole exomic sequencing for analysis of acquired resistance

BRAF Mutant Gastrointestinal Stromal Tumor: First report of regression with BRAF inhibitor dabrafenib (GSK2118436) and whole exomic sequencing for analysis of acquired resistance

https://doi.org/10.18632/oncotarget.864

Gerald S. Falchook, Jonathan C. Trent, Michael C. Heinrich, Carol Beadling, Janice Patterson, Christel C. Bastida, Samuel C. Blackman,  and Razelle Kurzrock
310-315
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Growth of poorly differentiated endometrial carcinoma is inhibited by combined action of medroxyprogesterone acetate and the Ras inhibitor Salirasib

Growth of poorly differentiated endometrial carcinoma is inhibited by combined action of medroxyprogesterone acetate and the Ras inhibitor Salirasib

https://doi.org/10.18632/oncotarget.867

Raya Faigenbaum, Roni Haklai, Gilad Ben-Baruch,  and Yoel Kloog
316-328
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Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1)

Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1)

https://doi.org/10.18632/oncotarget.834

Kristen M. Reipas, Jennifer H. Law, Nicole Couto, Sumaiya Islam, Yvonne Li, Huifang Li, Artem Cherkasov, Karen Jung, Amarpal S. Cheema, Steven J.M. Jones, John A. Hassell,  and Sandra E. Dunn
329-345
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Mesenchymal stem cells deliver synthetic microRNA mimics to glioma cells and glioma stem cells and inhibit their cell migration and self-renewal

Mesenchymal stem cells deliver synthetic microRNA mimics to glioma cells and glioma stem cells and inhibit their cell migration and self-renewal

https://doi.org/10.18632/oncotarget.868

Hae-Kyung Lee, Susan Finniss, Simona Cazacu, Efrat Bucris, Amotz Ziv-Av, Cunli Xiang, Kevin Bobbitt, Sandra Rempel, Laura Hasselbach, Tom Mikkelsen, Shimon Slavin,  and Chaya Brodie
346-361
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Actin-binding protein alpha-actinin 4 (ACTN4) is a transcriptional co-activator of RelA/p65 sub-unit of NF-kB.

Actin-binding protein alpha-actinin 4 (ACTN4) is a transcriptional co-activator of RelA/p65 sub-unit of NF-kB.

https://doi.org/10.18632/oncotarget.901

Vasilisa Aksenova, Lidia Turoverova, Mikhail Khotin, Karl-Eric Magnusson, Eugene Tulchinsky, Gerry Melino, George P Pinaev, Nikolai Barlev,  and Dmitri Tentler
362-372
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