Oncotarget

Vol 3, No 11

November 2012

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About The Cover

The cover for the November issue of Oncotarget was taken from a series of images showing the effects of miR-98 on cell activities. Pictured above is the GFP expression of anti-miR-98 cells. See Siragam et al.

Table of Contents

Editorial

Neurophilin-1 in tumor growth

Neurophilin-1 in tumor growth

https://doi.org/10.18632/oncotarget.734

Shailendra Kapoor
1259
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Toll-like receptor 2: therapeutic target for gastric carcinogenesis

Toll-like receptor 2: therapeutic target for gastric carcinogenesis

https://doi.org/10.18632/oncotarget.735

William McCormack, Masanobu Oshima, Patrick Tan,  and Brendan Jenkins
1260-1261
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KRAS above and beyond – EGFR in pancreatic cancer

KRAS above and beyond – EGFR in pancreatic cancer

https://doi.org/10.18632/oncotarget.750

Jens T. Siveke,  and Howard C. Crawford
1262-1263
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Epigenetics, c-Myc and Aggressive B-cell Lymphomas

Epigenetics, c-Myc and Aggressive B-cell Lymphomas

https://doi.org/10.18632/oncotarget.748

Yizhuo Zhang, Xiaohong Zhao,  and Jianguo Tao
1264-1265
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Genetic Induction of the Warburg Effect Inhibits Tumor Growth

Genetic Induction of the Warburg Effect Inhibits Tumor Growth

https://doi.org/10.18632/oncotarget.739

Federica Sotgia, Ubaldo E. Martinez-Outschoorn,  and Michael P. Lisanti
1266-1267
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miR-150: targeting MLL leukemia

miR-150: targeting MLL leukemia

https://doi.org/10.18632/oncotarget.736

Xi Jiang,  and Jianjun Chen
1268-1269
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Immunosurveillance against cancer-associated hyperploidy

Immunosurveillance against cancer-associated hyperploidy

https://doi.org/10.18632/oncotarget.753

Laura Senovilla, Lorenzo Galluzzi, Guillermo Marino, Ilio Vitale, Maria Castedo,  and Guido Kroemer
1270-1271
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Reviews

NRF2 and p53: Januses in cancer?

NRF2 and p53: Januses in cancer?

https://doi.org/10.18632/oncotarget.754

Barak Rotblat, Gerry Melino,  and Richard A. Knight
1272-1283
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Spliceosome mutations in myelodysplastic syndromes and chronic myelomonocytic leukemia

Spliceosome mutations in myelodysplastic syndromes and chronic myelomonocytic leukemia

https://doi.org/10.18632/oncotarget.749

Virginie Chesnais, Olivier Kosmider, Frederik Damm, Raphael Itzykson, Olivier A Bernard, Eric Solary,  and Michaela Fontenay
1284-1293
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Research Perspectives

Identification of acetylation-dependent regulatory mechanisms that govern the oncogenic functions of Skp2

Identification of acetylation-dependent regulatory mechanisms that govern the oncogenic functions of Skp2

https://doi.org/10.18632/oncotarget.740

Zhiwei Wang, Hiroyuki Inuzuka, Jiateng Zhong, Pengda Liu, Fakul H Sarkar, Yi Sun,  and Wenyi Wei
1294-1300
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The Interfaces Between Signal Transduction Pathways: IGF-1/mTor, p53 and the Parkinson Disease Pathway

The Interfaces Between Signal Transduction Pathways: IGF-1/mTor, p53 and the Parkinson Disease Pathway

https://doi.org/10.18632/oncotarget.759

Arnold J. Levine, Chris R. Harris,  and Anna M. Puzio-Kuter
1301-1307
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Research Papers

Recurrent targets of aberrant somatic hypermutation in lymphoma

Recurrent targets of aberrant somatic hypermutation in lymphoma

https://doi.org/10.18632/oncotarget.653

Alireza Hadj Khodabakhshi, Ryan D Morin, Anthony P Fejes, Andrew J Mungall, Karen L Mungall, Madison Bolger-Munro, Nathalie A Johnson, Joseph M Connors, Randy D Gascoyne, Marco A Marra, Inanc Birol,  and Steven JM Jones
1308-1319
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Genes affected by mouse mammary tumor virus (MMTV) proviral insertions in mouse mammary tumors are deregulated or mutated in primary human mammary tumors.

Genes affected by mouse mammary tumor virus (MMTV) proviral insertions in mouse mammary tumors are deregulated or mutated in primary human mammary tumors.

https://doi.org/10.18632/oncotarget.682

Robert Callahan, Uma Mudunuri, Sharon Bargo, Ahmed Raafat, David McCurdy, Corinne Boulanger, William Lowther, Robert Stephens, Brian T. Luke, Claudia Stewart, Xiaolin Wu, David Munroe,  and Gilbert H. Smith
1320-1334
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Residual malignant and normal plasma cells shortly after high dose melphalan and stem cell transplantation. Highlight of a putative therapeutic window in Multiple Myeloma?

Residual malignant and normal plasma cells shortly after high dose melphalan and stem cell transplantation. Highlight of a putative therapeutic window in Multiple Myeloma?

https://doi.org/10.18632/oncotarget.650

Anouk Caraux, Laure Vincent, Salahedine Bouhya, Philippe Quittet, Jérôme Moreaux, Guilhem Requirand, Jean-Luc Veyrune, Gaëlle Olivier, Guillaume Cartron, Jean-François Rossi,  and Bernard Klein
1335-1347
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Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN

Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN

https://doi.org/10.18632/oncotarget.694

Andrew D Beggs, Enric Domingo, Megan McGregor, Mikael Presz, Elaine Johnstone, Rachel Midgley, David Kerr, Dahmane Oukrif, Marco Novelli, Muti Abulafi, Shirley V Hodgson, Wakkas Fadhil, Mohammed Ilyas,  and Ian P Tomlinson
1348-1355
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Pyruvate kinase is a dosage-dependent regulator of cellular amino acid homeostasis

Pyruvate kinase is a dosage-dependent regulator of cellular amino acid homeostasis

https://doi.org/10.18632/oncotarget.730

Katharina Bluemlein, Matthias Glueckmann, Nana-Maria Grüning, René Feichtinger, Antje Krüger, Mirjam MC. Wamelink, Hans Lehrach, Stephen Tate, Daniel Neureiter, Kofler Barbara,  and Markus Ralser
1356-1369
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA miR-98 inhibits tumor angiogenesis and invasion by targeting activin receptor-like kinase-4 and matrix metalloproteinase-11

MicroRNA miR-98 inhibits tumor angiogenesis and invasion by targeting activin receptor-like kinase-4 and matrix metalloproteinase-11

https://doi.org/10.18632/oncotarget.717

Vinayakumar Siragam, Zina Jeyapalan Rutnam, Weining Yang, Ling Fang, Linlin Luo, Xiangling Yan, Minhui Li, Zhaoqun Deng, Jun Qian, Chun Peng,  and Burton B. Yang
1370-1385
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Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma

Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.709

Takashi Kinoshita, Toyoyuki Hanazawa, Nijiro Nohata, Naoko Kikkawa, Hideki Enokida, Hirofumi Yoshino, Takeshi Yamasaki, Hideo Hidaka, Masayuki Nakagawa, Yoshitaka Okamoto,  and Naohiko Seki
1386-1400
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting MCT-1 oncogene inhibits Shc pathway and xenograft tumorigenicity

Targeting MCT-1 oncogene inhibits Shc pathway and xenograft tumorigenicity

https://doi.org/10.18632/oncotarget.688

Hung-Ju Shih, Hsiao-Huei Chen, Yen-An Chen, Meng-Hsun Wu, Gan-Guang Liou, Wei-Wen Chang, Linyi Chen, Lu-Hai Wang,  and Hsin-Ling Hsu
1401-1415
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Superior efficacy of co-treatment with dual PI3K/mTOR inhibitor NVP-BEZ235 and pan-histone deacetylase inhibitor against human pancreatic cancer

Superior efficacy of co-treatment with dual PI3K/mTOR inhibitor NVP-BEZ235 and pan-histone deacetylase inhibitor against human pancreatic cancer

https://doi.org/10.18632/oncotarget.724

Sreedhar Venkannagari, Warren Fiskus, Karissa Peth, Peter Atadja, Manuel Hidalgo, Anirban Maitra,  and Kapil N Bhalla
1416-1427
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Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans

Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans

https://doi.org/10.18632/oncotarget.746

Kyle M. Walsh, Christopher I. Amos, Angela S. Wenzlaff, Ivan P. Gorlov, Jennette D. Sison, Xifeng Wu, Margaret R. Spitz, Helen M. Hansen, Emily Y. Lu, Chongjuan Wei, Huifeng Zhang, Wei Chen, Stacy M. Lloyd, Marsha L. Frazier, Paige M. Bracci, Michael F. Seldin, Margaret R. Wrensch, Ann G. Schwartz,  and John K. Wiencke
1428-1438
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Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis, Chemosensitivity and Radiosensitivity

Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis, Chemosensitivity and Radiosensitivity

https://doi.org/10.18632/oncotarget.683

Swapna Asuthkar, Kiran Kumar Velpula, Chandramu Chetty, Bharathi Gorantla,  and Jasti S. Rao
1439-1454
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Identification of miR-30d as a novel prognostic maker of prostate cancer.

Identification of miR-30d as a novel prognostic maker of prostate cancer.

https://doi.org/10.18632/oncotarget.696

Naohito Kobayashi, Hiroji Uemura, Kiyotaka Nagahama, Koji Okudela, Mitsuko Furuya, Yoko Ino, Yusuke Ito, Hisashi Hirano, Yoshiaki Inayama, Ichiro Aoki, Yoji Nagashima, Yoshinobu Kubota,  and Hitoshi Ishiguro
1455-1471
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Targeting HIF2α Translation with Tempol in VHL-Deficient Clear Cell Renal Cell Carcinoma

Targeting HIF2α Translation with Tempol in VHL-Deficient Clear Cell Renal Cell Carcinoma

https://doi.org/10.18632/oncotarget.561

Carole Sourbier, Gaurav Srivastava, Manik C. Ghosh, Sanchari Ghosh, Youfeng Yang, Gopal Gupta, William DeGraff, Murali C. Krishna, James B. Mitchell, Tracey A. Rouault,  and W. Marston Linehan
1472-1482
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