Oncotarget

Vol 3, No 4

April 2012

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About The Cover

Bone marrow plasma cells from a multiple myeloma patient after CD138 bead purification. See Tschumper et al.

Table of Contents

Editorial Comments

Pro-malignant properties of STAT3 during chronic inflammation

Pro-malignant properties of STAT3 during chronic inflammation

DOI: 10.18632/oncotarget.482

Marco Demaria,  and Valeria Poli
359-360
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Attacking tumor cells with a dual ligand for innate immune receptors

Attacking tumor cells with a dual ligand for innate immune receptors

DOI: 10.18632/oncotarget.484

Johan Garaude,  and J. Magarian Blander
361-362
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Accelerating cancer evolution: a dark side of SIRT1 in genome maintenance

Accelerating cancer evolution: a dark side of SIRT1 in genome maintenance

DOI: 10.18632/oncotarget.487

WenYong Chen
363-364
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Reviews

Targeting Cancer Gene Therapy with Magnetic Nanoparticles

Targeting Cancer Gene Therapy with Magnetic Nanoparticles

DOI: 10.18632/oncotarget.490

Charles Li, Linda Li,  and Andrew C. Keate
365-370
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Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment

Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment

DOI: 10.18632/oncotarget.477

Alberto M. Martelli, Francesca Chiarini, Camilla Evangelisti, Alessandra Cappellini, Francesca Buontempo, Daniela Bressanin, Milena Fini,  and James A. McCubrey
371-394
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Brief Reports

Metformin-induced preferential killing of breast cancer initiating CD44+CD24-/low cells is sufficient to overcome primary resistance to trastuzumab in HER2+ human breast cancer xenografts

Metformin-induced preferential killing of breast cancer initiating CD44+CD24-/low cells is sufficient to overcome primary resistance to trastuzumab in HER2+ human breast cancer xenografts

DOI: 10.18632/oncotarget.488

Sílvia Cufí, Bruna Corominas-Faja, Alejandro Vazquez-Martin, Cristina Oliveras-Ferraros, Joan Dorca, Joaquim Bosch-Barrera, Begoña Martin-Castillo,  and Javier A Menendez
395-398
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Research Papers

Aggressiveness of human melanoma xenograft models is promoted by aneuploidy-driven gene expression deregulation

Aggressiveness of human melanoma xenograft models is promoted by aneuploidy-driven gene expression deregulation

DOI: 10.18632/oncotarget.473

Veronique Mathieu, Christine Pirker, Wolfgang M Schmidt, Sabine Spiegl-Kreinecker, Daniela Lötsch, Petra Heffeter, Balazs Hegedus, Michael Grusch, Robert Kiss,  and Walter Berger
399-413
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Folate Receptor Alpha Expression in Lung Cancer: Diagnostic and Prognostic Significance

Folate Receptor Alpha Expression in Lung Cancer: Diagnostic and Prognostic Significance

DOI: 10.18632/oncotarget.519

Daniel J. O'Shannessy, Gordon Yu, Robert Smale, Yao-Shi Fu, Sunil Singhal, Robert P. Thiel, Elizabeth B. Somers,  and Anil Vachani
414-425
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Properties of Mechano-Transduction via Simulated Microgravity and its Effects on Intracellular Trafficking of VEGFR’s

Properties of Mechano-Transduction via Simulated Microgravity and its Effects on Intracellular Trafficking of VEGFR’s

DOI: 10.18632/oncotarget.472

Andrew Puca, Giuseppe Russo,  and Antonio Giordano
426-434
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Regulation of macroautophagy in ovarian cancer cells in vitro and in vivo by controlling Glucose regulatory protein 78 and AMPK

Regulation of macroautophagy in ovarian cancer cells in vitro and in vivo by controlling Glucose regulatory protein 78 and AMPK

DOI: 10.18632/oncotarget.483

Prabodh K. Kandala,  and Sanjay K. Srivastava
435-449
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Methylation profiling of normal individuals reveals mosaic promoter methylation of cancer-associated genes.

Methylation profiling of normal individuals reveals mosaic promoter methylation of cancer-associated genes.

DOI: 10.18632/oncotarget.480

Lasse S. Kristensen, Michael P. Raynor, Ida L. Candiloro,  and Alexander Dobrovic
450-461
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On the presence and role of human gene-body DNA methylation

On the presence and role of human gene-body DNA methylation

DOI: 10.18632/oncotarget.497

Daudi Jjingo, Andrew B. Conley, Soojin V. Yi, Victoria V. Lunyak,  and I. King Jordan
462-474
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Singular v Dual Inhibition of SNF2L and Its Isoform, SNF2LT, Have Similar Effects on DNA Damage but Opposite Effects on the DNA Damage Response, Cancer Cell Growth Arrest and Apoptosis

Singular v Dual Inhibition of SNF2L and Its Isoform, SNF2LT, Have Similar Effects on DNA Damage but Opposite Effects on the DNA Damage Response, Cancer Cell Growth Arrest and Apoptosis

DOI: 10.18632/oncotarget.479

Yin Ye, Yi Xiao, Wenting Wang, Jian-Xin Gao, Kurtis Yearsley, Quintao Yan,  and Sanford H. Barsky
475-489
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BCL2L10 is a predictive factor for resistance to Azacitidine in MDS and AML patients

BCL2L10 is a predictive factor for resistance to Azacitidine in MDS and AML patients

DOI: 10.18632/oncotarget.481

Thomas Cluzeau, Guillaume Robert, Nicolas Mounier, Jean Michel Karsenti, Maeva Dufies, Alexandre Puissant, Arnaud Jacquel, Aline Renneville, Claude Preudhomme, Jill Patrice Cassuto, Sophie Raynaud, Frederic Luciano,  and Patrick Auberger
490-501
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Methodological Reports

Comprehensive Assessment of Potential Multiple Myeloma Immunoglobulin Heavy Chain V-D-J Intraclonal Variation Using Massively Parallel Pyrosequencing

Comprehensive Assessment of Potential Multiple Myeloma Immunoglobulin Heavy Chain V-D-J Intraclonal Variation Using Massively Parallel Pyrosequencing

DOI: 10.18632/oncotarget.469

Renee C. Tschumper, Yan W. Asmann, Asif Hossain, Paul M. Huddleston, Xiaosheng Wu, Angela Dispenzieri, Bruce W. Eckloff,  and Diane F. Jelinek
502-513
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