Oncotarget

Vol 2, No 8

August 2011

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About The Cover

Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers. Quantitative analysis of the hierarchical distribution of 5hmC in stratified epithelia. Representative micrograph of normal prostate epithelia co-immunolabeled for 5hmC (red) and basal cell specific cytokeratin 903 (green). Nuclei were counterstained with DAPI (blue). See Haffner et al.

Table of Contents

Editorial Comments

Inhibition of Wnt signaling and cancer stem cells

Inhibition of Wnt signaling and cancer stem cells

DOI: 10.18632/oncotarget.309

Desheng Lu,  and Dennis A. Carson
587
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Unraveling the complexity of basal-like breast cancer

Unraveling the complexity of basal-like breast cancer

DOI: 10.18632/oncotarget.314

Lauren L. C. Marotta,  and Kornelia Polyak
588-589
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Reviews

Mouse Models to Interrogate the Implications of the Differentiation Status In the Ontogeny of Gliomas

Mouse Models to Interrogate the Implications of the Differentiation Status In the Ontogeny of Gliomas

DOI: 10.18632/oncotarget.319

Diana Marcela Muñoz,  and Abhijit Guha
590-598
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Research Papers

Aurora Kinase Inhibition Overcomes Cetuximab Resistance in Squamous Cell Cancer of the Head and Neck

Aurora Kinase Inhibition Overcomes Cetuximab Resistance in Squamous Cell Cancer of the Head and Neck

DOI: 10.18632/oncotarget.311

Alexander Hoellein, Anja Pickhard, Fabienne von Keitz, Stephanie Schoeffmann, Guido Piontek, Martina Rudelius, Anja Baumgart, Stefan Wagenpfeil, Christian Peschel, Tobias Dechow, Henning Bier,  and Ulrich Keller
599-609
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Cooperative Effects of Akt-1 and Raf-1 on the Induction of Cellular Senescence in Doxorubicin or Tamoxifen Treated Breast Cancer Cells

Cooperative Effects of Akt-1 and Raf-1 on the Induction of Cellular Senescence in Doxorubicin or Tamoxifen Treated Breast Cancer Cells

DOI: 10.18632/oncotarget.315

Jackson R. Taylor, Brian D. Lehmann, William H. Chappell, Stephen L. Abrams, Linda S. Steelman,  and James A. McCubrey
610-626
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Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers

Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers

DOI: 10.18632/oncotarget.316

Michael Christoph Haffner, Alcides Chaux, Alan K Meeker, David Esopi, Jonathan Gerber, Laxmi G. Pellakuru, Antoun Toubaji, Pedram Argani, Christine Iacobuzio-Donahue, William G. Nelson, George J. Netto, Angelo DeMarzo,  and Srinivasan Yegnasubramanian
627-637
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Research Perspectives

The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer

The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer

DOI: 10.18632/oncotarget.310

Tapati Mazumdar, Jennifer DeVecchio, Akwasi Agyeman, Ting Shi,  and Janet A. Houghton
638-645
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The NFκB pathway: a therapeutic target in glioblastoma

The NFκB pathway: a therapeutic target in glioblastoma

DOI: 10.18632/oncotarget.322

Lorena Nogueira, Patricia Ruiz-Ontañon, Alfonso Vazquez-Barquero, Francisco Moris,  and Jose L. Fernandez-Luna
646-653
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