Oncotarget

Vol 8, No 39

September 12, 2017

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About The Cover

The cover for issue 39 of Oncotarget features Figure 3A, "Network analysis using the consolidated interactome of differentially expressed genes between miR-21 ZIP and CTL ZIP MEFs treated with rapamcyin (20nM, 24h), red upregulated, green-downregulated, thick border- predicted targets of miR-21," from Lam, et al.

Table of Contents

News

Synergistic treatment of TS

Synergistic treatment of TS

https://doi.org/10.18632/oncotarget.20024

Aditi U. Gurkar,  and Toren Finkel
64653-64654
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Editorial

DPP4 inhibition prevents AKI

DPP4 inhibition prevents AKI

https://doi.org/10.18632/oncotarget.20212

Christoph Reichetzeder,  and Berthold Hocher
64655-64656
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Priority Research Papers

p53 upregulates PLCε-IP3-Ca2+ pathway and inhibits autophagy through its target gene Rap2B

p53 upregulates PLCε-IP3-Ca2+ pathway and inhibits autophagy through its target gene Rap2B

https://doi.org/10.18632/oncotarget.18112

Jiehui Di, Juanjuan Tang, Heya Qian, Derek A. Franklin, Chad Deisenroth, Yoko Itahana, Junnian Zheng,  and Yanping Zhang
64657-64669
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Analyses of germline variants associated with ovarian cancer survival identify functional candidates at the 1q22 and 19p12 outcome loci

Analyses of germline variants associated with ovarian cancer survival identify functional candidates at the 1q22 and 19p12 outcome loci

https://doi.org/10.18632/oncotarget.18501

Dylan M. Glubb, Sharon E. Johnatty, Michael C.J. Quinn, Tracy A. O’Mara, Jonathan P. Tyrer, Bo Gao, Peter A. Fasching, Matthias W. Beckmann, Diether Lambrechts, Ignace Vergote, Digna R. Velez Edwards, Alicia Beeghly-Fadiel, Javier Benitez, Maria J. Garcia, Marc T. Goodman, Pamela J. Thompson, Thilo Dörk, Matthias Dürst, Francesmary Modungo, Kirsten Moysich, Florian Heitz, Andreas du Bois, Jacobus Pfisterer, Peter Hillemanns, On behalf of the AGO Study Group, Beth Y. Karlan, Jenny Lester, Ellen L. Goode, Julie M. Cunningham, Stacey J. Winham, Melissa C. Larson, Bryan M. McCauley, Susanne Krüger Kjær, Allan Jensen, Joellen M. Schildkraut, Andrew Berchuck, Daniel W. Cramer, Kathryn L. Terry, Helga B. Salvesen, Line Bjorge, Penny M. Webb, Peter Grant, Tanja Pejovic, Melissa Moffitt, Claus K. Hogdall, Estrid Hogdall, James Paul, Rosalind Glasspool, Marcus Bernardini, Alicia Tone, David Huntsman, Michelle Woo, AOCS Group, Anna deFazio, Catherine J. Kennedy, Stuart MacGregor, Stuart MacGregor,  and Georgia Chenevix-Trench
64670-64684
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Exome sequencing analysis of murine medulloblastoma models identifies WDR11 as a potential tumor suppressor in Group 3 tumors

Exome sequencing analysis of murine medulloblastoma models identifies WDR11 as a potential tumor suppressor in Group 3 tumors

https://doi.org/10.18632/oncotarget.19642

Lei Wei, Brian L. Murphy, Gang Wu, Matthew Parker, John Easton, Richard J. Gilbertson, Jinghui Zhang,  and Martine F. Roussel
64685-64697
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The β-NAD+ salvage pathway and PKC-mediated signaling influence localized PARP-1 activity and CTCF Poly(ADP)ribosylation

The β-NAD+ salvage pathway and PKC-mediated signaling influence localized PARP-1 activity and CTCF Poly(ADP)ribosylation

https://doi.org/10.18632/oncotarget.19841

David J.P. Henderson, JJ L. Miranda,  and Beverly M. Emerson
64698-64713
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Rapamycin-induced miR-21 promotes mitochondrial homeostasis and adaptation in mTORC1 activated cells

Rapamycin-induced miR-21 promotes mitochondrial homeostasis and adaptation in mTORC1 activated cells

https://doi.org/10.18632/oncotarget.19947

Hilaire C. Lam, Heng-Jia Liu, Christian V. Baglini, Harilaos Filippakis, Nicola Alesi, Julie Nijmeh, Heng Du, Alicia Llorente Lope, Katherine A. Cottrill, Adam Handen, John M. Asara, David J. Kwiatkowski, Issam Ben-Sahra, William M. Oldham, Stephen Y. Chan,  and Elizabeth P. Henske
64714-64727
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A ketogenic diet supplemented with medium-chain triglycerides enhances the anti-tumor and anti-angiogenic efficacy of chemotherapy on neuroblastoma xenografts in a CD1-nu mouse model

A ketogenic diet supplemented with medium-chain triglycerides enhances the anti-tumor and anti-angiogenic efficacy of chemotherapy on neuroblastoma xenografts in a CD1-nu mouse model

https://doi.org/10.18632/oncotarget.20041

Sepideh Aminzadeh-Gohari, René Günther Feichtinger, Silvia Vidali, Felix Locker, Tricia Rutherford, Maura O’Donnel, Andrea Stöger-Kleiber, Johannes Adalbert Mayr, Wolfgang Sperl,  and Barbara Kofler
64728-64744
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Research Papers: Gerotarget (Focus on Aging)

Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer’s disease and other tauopathies

Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer’s disease and other tauopathies

https://doi.org/10.18632/oncotarget.17371

Fulvio Florenzano, Corsetti Veronica, Gabriele Ciasca, Maria Teresa Ciotti, Anna Pittaluga, Gunedalina Olivero, Marco Feligioni, Filomena Iannuzzi, Valentina Latina, Michele Francesco Maria Sciacca, Alessandro Sinopoli, Danilo Milardi, Giuseppe Pappalardo, De Spirito Marco, Massimiliano Papi, Anna Atlante, Antonella Bobba, Antonella Borreca, Pietro Calissano,  and Giuseppina Amadoro
64745-64778
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Ginsenoside Rg3 inhibits the senescence of prostate stromal cells through down-regulation of interleukin 8 expression

Ginsenoside Rg3 inhibits the senescence of prostate stromal cells through down-regulation of interleukin 8 expression

https://doi.org/10.18632/oncotarget.17616

Yanfei Peng, Ran Zhang, Lingfei Kong, Yongmei Shen, Da Xu, Fang Zheng, Jianwei Liu, Qian Wu, Bona Jia,  and Ju Zhang
64779-64792
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Spermine and spermidine reversed age-related cardiac deterioration in rats

Spermine and spermidine reversed age-related cardiac deterioration in rats

https://doi.org/10.18632/oncotarget.18334

Hao Zhang, Junying Wang, Lingxu Li, Nannan Chai, Yuhan Chen, Feixiang Wu, Weihua Zhang, Lina Wang, Sa Shi, Li Zhang, Shuling Bian, Changqing Xu, Ye Tian,  and Yajun Zhao
64793-64808
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Intermittent treatment with farnesyltransferase inhibitor and sulforaphane improves cellular homeostasis in Hutchinson-Gilford progeria fibroblasts

Intermittent treatment with farnesyltransferase inhibitor and sulforaphane improves cellular homeostasis in Hutchinson-Gilford progeria fibroblasts

https://doi.org/10.18632/oncotarget.19363

Diana Gabriel, Dinah Dorith Shafry, Leslie B. Gordon,  and Karima Djabali
64809-64826
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Research Papers: Pathology

Long non-coding RNA H19 induces hippocampal neuronal apoptosis via Wnt signaling in a streptozotocin-induced rat model of diabetes mellitus

Long non-coding RNA H19 induces hippocampal neuronal apoptosis via Wnt signaling in a streptozotocin-induced rat model of diabetes mellitus

https://doi.org/10.18632/oncotarget.17472

Yu-Hao Zhao, Tie-Feng Ji, Qi Luo,  and Jin-Lu Yu
64827-64839
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RASAL1 is a potent regulator of hepatic stellate cell activity and liver fibrosis

RASAL1 is a potent regulator of hepatic stellate cell activity and liver fibrosis

https://doi.org/10.18632/oncotarget.17609

Akemi Takata, Motoyuki Otsuka, Takahiro Kishikawa, Mari Yamagami, Rei Ishibashi, Kazuma Sekiba, Tatsunori Suzuki, Motoko Ohno, Yui Yamashita, Takaya Abe, Ryota Masuzaki, Tsuneo Ikenoue,  and Kazuhiko Koike
64840-64852
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Activation of cannabinoid receptor type II by AM1241 protects adipose-derived mesenchymal stem cells from oxidative damage and enhances their therapeutic efficacy in myocardial infarction mice via Stat3 activation

Activation of cannabinoid receptor type II by AM1241 protects adipose-derived mesenchymal stem cells from oxidative damage and enhances their therapeutic efficacy in myocardial infarction mice via Stat3 activation

https://doi.org/10.18632/oncotarget.17614

Dong Han, Xiang Li, Wen-Si Fan, Jiang-Wei Chen, Tian-Tian Gou, Tao Su, Miao-Miao Fan, Meng-Qi Xu, Ya-Bin Wang, Sai Ma, Ya Qiu,  and Feng Cao
64853-64866
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Tsp1 promotes alveolar stem cell proliferation and its down-regulation relates to lung inflammation in intralobar pulmonary sequestration

Tsp1 promotes alveolar stem cell proliferation and its down-regulation relates to lung inflammation in intralobar pulmonary sequestration

https://doi.org/10.18632/oncotarget.19952

Kuan Li, Qi Wu, Xin Sun, Yan Geng, Dong Leng, Hongwei Li, Subei Zhang, Qiaoxing Wang, Junping Wu, Long Xu, Xue Li, Yu Li, Qiuyang Zhang, Adrianne Kurkciyan, Jiurong Liang, Dianhua Jiang,  and Huaiyong Chen
64867-64877
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Research Papers: Immunology

Dietary ZnO nanoparticles alters intestinal microbiota and inflammation response in weaned piglets

Dietary ZnO nanoparticles alters intestinal microbiota and inflammation response in weaned piglets

https://doi.org/10.18632/oncotarget.17612

Tian Xia, Wenqing Lai, Miaomiao Han, Meng Han, Xi Ma,  and Liying Zhang
64878-64891
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A cellular platform for the evaluation of immune checkpoint molecules

A cellular platform for the evaluation of immune checkpoint molecules

https://doi.org/10.18632/oncotarget.17615

Sabrina Jutz, Annika Hennig, Wolfgang Paster, Ömer Asrak, Dejana Dijanovic, Florian Kellner, Winfried F. Pickl, Johannes B. Huppa, Judith Leitner,  and Peter Steinberger
64892-64906
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Research Papers

Rat embryonic fibroblasts immortalized by MRPS18-2 protein are target for NK-cells

Rat embryonic fibroblasts immortalized by MRPS18-2 protein are target for NK-cells

https://doi.org/10.18632/oncotarget.17610

Muhammad Mushtaq, Pradeepa N. Pangigadde, Suhas Darekar, Erik Dissen,  and Elena Kashuba
64907-64917
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Lysine methylation of FEN1 by SET7 is essential for its cellular response to replicative stress

Lysine methylation of FEN1 by SET7 is essential for its cellular response to replicative stress

https://doi.org/10.18632/oncotarget.18070

Palaniraja Thandapani, Anthony M. Couturier, Zhenbao Yu, Xing Li, Jean-François Couture, Shawn Li, Jean-Yves Masson,  and Stéphane Richard
64918-64931
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Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells

Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells

https://doi.org/10.18632/oncotarget.18117

N. Sumru Bayin, Joshua D. Frenster, Rajeev Sen, Sheng Si, Aram S. Modrek, Nataliya Galifianakis, Igor Dolgalev, Valerio Ortenzi, Irineu Illa-Bochaca, Anadjeet Khahera, Jonathan Serrano, Luis Chiriboga, David Zagzag, John G. Golfinos, Werner Doyle, Aristotelis Tsirigos, Adriana Heguy, Mitch Chesler, Mary Helen Barcellos-Hoff, Matija Snuderl,  and Dimitris G. Placantonakis
64932-64953
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Marital status and survival in patients with primary liver cancer

Marital status and survival in patients with primary liver cancer

https://doi.org/10.18632/oncotarget.11066

Xing-Kang He, Zheng-Hua Lin, Yun Qian, Daheng Xia, Piaopiao Jin,  and Lei-Min Sun
64954-64963
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Quercetin induced ROS production triggers mitochondrial cell death of human embryonic stem cells

Quercetin induced ROS production triggers mitochondrial cell death of human embryonic stem cells

https://doi.org/10.18632/oncotarget.11070

So-Yeon Kim, Ho-Chang Jeong, Soon-Ki Hong, Mi-Ok Lee, Seung-Ju Cho,  and Hyuk-Jin Cha
64964-64973
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SOX7 promotes the maintenance and proliferation of B cell precursor acute lymphoblastic cells

SOX7 promotes the maintenance and proliferation of B cell precursor acute lymphoblastic cells

https://doi.org/10.18632/oncotarget.10472

Sara Cuvertino, Genny Filiciotto, Ashish Masurekar, Vaskar Saha, Georges Lacaud,  and Valerie Kouskoff
64974-64983
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Lyn mediates FIP1L1-PDGFRA signal pathway facilitating IL- 5RA intracellular signal through FIP1L1-PDGFRA/JAK2/Lyn/Akt network complex in CEL

Lyn mediates FIP1L1-PDGFRA signal pathway facilitating IL- 5RA intracellular signal through FIP1L1-PDGFRA/JAK2/Lyn/Akt network complex in CEL

https://doi.org/10.18632/oncotarget.11401

Bin Li, Guangsen Zhang, Cui Li, Ruijuan Li, Jingchen Lu, Zhengxi He, Quan Wang, Zhenzi Peng, Jun Wang, Yeping Dong, Chunfang Zhang, JieQiong Tan, Nacef Bahri, Yuexiang Wang,  and Chaojun Duan
64984-64998
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Molecular profiling of colorectal pulmonary metastases and primary tumours: implications for targeted treatment

Molecular profiling of colorectal pulmonary metastases and primary tumours: implications for targeted treatment

https://doi.org/10.18632/oncotarget.17048

Sing Y. Moorcraft, Thomas Jones, Brian A. Walker, George Ladas, Eleftheria Kalaitzaki, Lina Yuan, Ruwaida Begum, Zakaria Eltahir, Andrew Wotherspoon, Angeles Montero-Fernandez, Larissa S. Teixeira Mendes, David Gonzalez de Castro, Sanna Hulkki Wilson, Paula Proszek, Ye M. To, Eliza Hawkes, Amitesh Roy, David Cunningham, Sheela Rao, David Watkins, Naureen Starling, Anne M. Bowcock,  and Ian Chau
64999-65008
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RNAi targeting Nogo Receptor enhanced survival and proliferation of murine retinal ganglion cells during N-methyl-D-aspartateinduced optic nerve crush

RNAi targeting Nogo Receptor enhanced survival and proliferation of murine retinal ganglion cells during N-methyl-D-aspartateinduced optic nerve crush

https://doi.org/10.18632/oncotarget.17351

Kun Zeng, Bo Zhong, Xiao-Li Shen, Min Fang, Bao-Tao Lin,  and Da-Hui Ma
65009-65021
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Metabolic characterization and pathway analysis of berberine protects against prostate cancer

Metabolic characterization and pathway analysis of berberine protects against prostate cancer

https://doi.org/10.18632/oncotarget.17531

Xianna Li, Aihua Zhang, Hui Sun, Zhidong Liu, Tianlei Zhang, Shi Qiu, Liang Liu,  and Xijun Wang
65022-65041
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Efficient intracellular delivery makes cancer cells sensitive to nanoemulsive chemodrugs

Efficient intracellular delivery makes cancer cells sensitive to nanoemulsive chemodrugs

https://doi.org/10.18632/oncotarget.17536

Shan Liu, Dilong Chen, Yuming Yuan, Xue Zhang, Yao Li, Shenglei Yan,  and Jingqing Zhang
65042-65055
Abstract  |  PDF  |  HTML  |  Order a Reprint

Nestin expression involves invasiveness of esophageal carcinoma and its downregulation enhances paclitaxel sensitivity to esophageal carcinoma cell apoptosis

Nestin expression involves invasiveness of esophageal carcinoma and its downregulation enhances paclitaxel sensitivity to esophageal carcinoma cell apoptosis

https://doi.org/10.18632/oncotarget.17774

Jinghang Zhang, Jiateng Zhong, Jian Yu, Jinsong Li, Wenyu Di, Ping Lu, Xiaoyu Yang, Weixing Zhao, Xianwei Wang,  and Wei Su
65056-65063
Abstract  |  PDF  |  HTML  |  Order a Reprint

The value of phosphohistone H3 as a proliferation marker for evaluating invasive breast cancers: A comparative study with Ki67

The value of phosphohistone H3 as a proliferation marker for evaluating invasive breast cancers: A comparative study with Ki67

https://doi.org/10.18632/oncotarget.17775

Ji-Ye Kim, Hyang Sook Jeong, Taek Chung, Moonsik Kim, Ji Hee Lee, Woo Hee Jung,  and Ja Seung Koo
65064-65076
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting SHP-1-STAT3 signaling: A promising therapeutic approach for the treatment of cholangiocarcinoma

Targeting SHP-1-STAT3 signaling: A promising therapeutic approach for the treatment of cholangiocarcinoma

https://doi.org/10.18632/oncotarget.17779

Ming-Hung Hu, Li-Ju Chen, Yen-Lin Chen, Ming-Shen Tsai, Chung-Wai Shiau, Tzu-I Chao, Chun-Yu Liu, Jia-Horng Kao,  and Kuen-Feng Chen
65077-65089
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting ADAM17 inhibits human colorectal adenocarcinoma progression and tumor-initiating cell frequency

Targeting ADAM17 inhibits human colorectal adenocarcinoma progression and tumor-initiating cell frequency

https://doi.org/10.18632/oncotarget.17780

Joseph Dosch, Elizabeth Ziemke, Shanshan Wan, Kathryn Luker, Theodore Welling, Karin Hardiman, Eric Fearon, Suneetha Thomas, Matthew Flynn, Jonathan Rios-Doria, Robert Hollingsworth, Ronald Herbst, Elaine Hurt,  and Judith Sebolt-Leopold
65090-65099
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oxymatrine suppresses the growth and invasion of MG63 cells by up-regulating PTEN and promoting its nuclear translocation

Oxymatrine suppresses the growth and invasion of MG63 cells by up-regulating PTEN and promoting its nuclear translocation

https://doi.org/10.18632/oncotarget.17783

Ming He, Linlin Jiang, Bin Li, Guangbin Wang, Jiashi Wang,  and Yonghui Fu
65100-65110
Abstract  |  PDF  |  HTML  |  Order a Reprint

Detection of activating and acquired resistant mutation in plasma from EGFR-mutated NSCLC patients by peptide nucleic acid (PNA) clamping-assisted fluorescence melting curve analysis

Detection of activating and acquired resistant mutation in plasma from EGFR-mutated NSCLC patients by peptide nucleic acid (PNA) clamping-assisted fluorescence melting curve analysis

https://doi.org/10.18632/oncotarget.17786

Chang Gon Kim, Hyo Sup Shim, Min Hee Hong, Yoon Jin Cha, Su Jin Heo, Hyung Soon Park, Jee Hung Kim, Jin Gu Lee, Chang Young Lee, Byoung Chul Cho,  and Hye Ryun Kim
65111-65122
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Anti-tumor activity of anthrax toxin variants that form a functional translocation pore by intermolecular complementation

Anti-tumor activity of anthrax toxin variants that form a functional translocation pore by intermolecular complementation

https://doi.org/10.18632/oncotarget.17729

Shihui Liu, Qian Ma, Rasem Fattah, Thomas H. Bugge,  and Stephen H. Leppla
65123-65131
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of circulating microRNA signatures as potential noninvasive biomarkers for prediction and prognosis of lymph node metastasis in gastric cancer

Identification of circulating microRNA signatures as potential noninvasive biomarkers for prediction and prognosis of lymph node metastasis in gastric cancer

https://doi.org/10.18632/oncotarget.17789

Xiumei Jiang, Wenfei Wang, Yongmei Yang, Lutao Du, Xiaoyun Yang, Lili Wang, Guixi Zheng, Weili Duan, Rui Wang, Xin Zhang, Lishui Wang, Xiaoyang Chen,  and Chuanxin Wang
65132-65142
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CD44 regulates prostate cancer proliferation, invasion and migration via PDK1 and PFKFB4

CD44 regulates prostate cancer proliferation, invasion and migration via PDK1 and PFKFB4

https://doi.org/10.18632/oncotarget.17821

Wei Li, Li Qian, Junhao Lin, Guihai Huang, Nan Hao, Xiuwang Wei, Wei Wang,  and Jianbo Liang
65143-65151
Abstract  |  PDF  |  HTML  |  Order a Reprint

Generation and evaluation of antibody agents for molecular imaging of CD44v6-expressing cancers

Generation and evaluation of antibody agents for molecular imaging of CD44v6-expressing cancers

https://doi.org/10.18632/oncotarget.17996

Anna-Karin Haylock, Johan Nilvebrant, Anja Mortensen, Irina Velikyan, Marika Nestor,  and Ronny Falk
65152-65170
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value of supraclavicular nodes and upper abdominal nodes metastasis after definitive chemoradiotherapy for patients with thoracic esophageal squamous cell carcinoma

Prognostic value of supraclavicular nodes and upper abdominal nodes metastasis after definitive chemoradiotherapy for patients with thoracic esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.18015

Xue Li, Lujun Zhao, Wencheng Zhang, Chengwen Yang, Zhen Lian, Shuai Wang, Ningbo Liu, Qingsong Pang, Ping Wang,  and Jinming Yu
65171-65185
Abstract  |  PDF  |  HTML  |  Order a Reprint

Serine 207 phosphorylated lysyl-tRNA synthetase predicts disease-free survival of non-small-cell lung carcinoma

Serine 207 phosphorylated lysyl-tRNA synthetase predicts disease-free survival of non-small-cell lung carcinoma

https://doi.org/10.18632/oncotarget.18053

Suliman Boulos, Min Chul Park, Marian Zeibak, Shen Yun Foo, Yoon Kyung Jeon, Young Tae Kim, Alex Motzik, Sagi Tshori, Tamar Hamburger, Sunghoon Kim, Hovav Nechushtan,  and Ehud Razin
65186-65198
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

DISC1 overexpression promotes non-small cell lung cancer cell proliferation

DISC1 overexpression promotes non-small cell lung cancer cell proliferation

https://doi.org/10.18632/oncotarget.18055

Shuo Wang, Ying-Ying Chen, Yu-Peng Li, Jun Gu, Shu-Dong Gu, Hai Shi, Xue-Song Li, Xiao-Ning Lu, Xiang Li, Shuang-Long Zhang, Kang-Jun Yu, Kun Liu,  and Li-Li Ji
65199-65210
Abstract  |  PDF  |  HTML  |  Order a Reprint

microRNA-22 can regulate expression of the long non-coding RNA MEG3 in acute myeloid leukemia

microRNA-22 can regulate expression of the long non-coding RNA MEG3 in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.18059

Hongxia Yao, Pei Sun, Mengling Duan, Lie Lin, Yanping Pan, Congming Wu, Xiangjun Fu, Hua Wang, Li Guo, Tianbo Jin,  and Yipeng Ding
65211-65217
Abstract  |  PDF  |  HTML  |  Order a Reprint

MiR-346 suppresses cell proliferation through SMYD3 dependent approach in hepatocellular carcinoma

MiR-346 suppresses cell proliferation through SMYD3 dependent approach in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.18060

Weiyou Zhu, Jing Qian, Ling Ma, Pei Ma, Fengming Yang,  and Yongqian Shu
65218-65229
Abstract  |  PDF  |  HTML  |  Order a Reprint

A20 functions as mediator in TNFα-induced injury of human umbilical vein endothelial cells through TAK1-dependent MAPK/eNOS pathway

A20 functions as mediator in TNFα-induced injury of human umbilical vein endothelial cells through TAK1-dependent MAPK/eNOS pathway

https://doi.org/10.18632/oncotarget.18191

Lei Li, Bingqing Huang, Shiyang Song, Hareshwaree Sohun, Zhiheng Rao, Luyuan Tao, Qike Jin, Jingjing Zeng, Rongzhou Wu, Kangting Ji, Jiafeng Lin, Lianpin Wu,  and Maoping Chu
65230-65239
Abstract  |  PDF  |  HTML  |  Order a Reprint

Environment and bladder cancer: molecular analysis by interaction networks

Environment and bladder cancer: molecular analysis by interaction networks

https://doi.org/10.18632/oncotarget.18222

Andrea Polo, Anna Crispo, Pellegrino Cerino, Luca Falzone, Saverio Candido, Aldo Giudice, Giuseppina De Petro, Gennaro Ciliberto, Maurizio Montella, Alfredo Budillon,  and Susan Costantini
65240-65252
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long non-coding RNA TUG1 promotes cervical cancer progression by regulating the miR-138-5p-SIRT1 axis

Long non-coding RNA TUG1 promotes cervical cancer progression by regulating the miR-138-5p-SIRT1 axis

https://doi.org/10.18632/oncotarget.18224

Jie Zhu, Huirong Shi, Huina Liu, Xiaojuan Wang,  and Fengmei Li
65253-65264
Abstract  |  PDF  |  HTML  |  Order a Reprint

Twist1 is highly expressed in cancer-associated fibroblasts of esophageal squamous cell carcinoma with a prognostic significance

Twist1 is highly expressed in cancer-associated fibroblasts of esophageal squamous cell carcinoma with a prognostic significance

https://doi.org/10.18632/oncotarget.17941

So-Young Yeo, Sang-Yun Ha, Keun-Woo Lee, Yan Cui, Zhao-Ting Yang, Yan-Hua Xuan,  and Seok-Hyung Kim
65265-65280
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Methylomics of nitroxidative stress on precancerous cells reveals DNA methylation alteration at the transition from in situ to invasive cervical cancer

Methylomics of nitroxidative stress on precancerous cells reveals DNA methylation alteration at the transition from in situ to invasive cervical cancer

https://doi.org/10.18632/oncotarget.18370

Po-Hsuan Su, Yao-Wen Hsu, Rui-Lan Huang, Yu-Chun Weng, Hui-Chen Wang, Yu-Chih Chen, Yueh-Ju Tsai, Chiou-Chung Yuan,  and Hung-Cheng Lai
65281-65291
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Does uneven geographic distribution of urologists effect bladder and prostate cancers mortality? National health insurance data in Korea from 2007–2011

Does uneven geographic distribution of urologists effect bladder and prostate cancers mortality? National health insurance data in Korea from 2007–2011

https://doi.org/10.18632/oncotarget.18036

Jae Heon Kim, Hwa Yeon Sun, Hyun Jung Kim, Young Myoung Ko, Dong-Il Chun,  and Jae Young Park
65292-65301
Abstract  |  PDF  |  HTML  |  Order a Reprint

The involvement of Nrf2 in the protective effects of (-)-Epigallocatechin-3-gallate (EGCG) on NaAsO2-induced hepatotoxicity

The involvement of Nrf2 in the protective effects of (-)-Epigallocatechin-3-gallate (EGCG) on NaAsO2-induced hepatotoxicity

https://doi.org/10.18632/oncotarget.18582

Xiao-Dong Han, Yan-Yan Zhang, Ke-Lei Wang, Yong-Pan Huang, Zhong-Bao Yang,  and Zhi Liu
65302-65312
Abstract  |  PDF  |  HTML  |  Order a Reprint

H2O2 attenuates IGF-1R tyrosine phosphorylation and its survival signaling properties in neuronal cells via NR2B containing NMDA receptor

H2O2 attenuates IGF-1R tyrosine phosphorylation and its survival signaling properties in neuronal cells via NR2B containing NMDA receptor

https://doi.org/10.18632/oncotarget.18625

Zhiwen Zeng, Dejun Wang, Uma Gaur, Liao Rifang, Haitao Wang,  and Wenhua Zheng
65313-65328
Abstract  |  PDF  |  HTML  |  Order a Reprint

Silencing protein kinase C ζ by microRNA-25-5p activates AMPK signaling and inhibits colorectal cancer cell proliferation

Silencing protein kinase C ζ by microRNA-25-5p activates AMPK signaling and inhibits colorectal cancer cell proliferation

https://doi.org/10.18632/oncotarget.18649

Shihu Zhang, Yiyang Zhang, Qing Cheng, Zhaoqun Ma, Guanwen Gong, Zhengming Deng, Kun Xu, Gaoyuan Wang, Yousong Wei,  and Xiaoping Zou
65329-65338
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Anti-SSTR2 peptide based targeted delivery of potent PLGA encapsulated 3,3’-diindolylmethane nanoparticles through blood brain barrier prevents glioma progression

Anti-SSTR2 peptide based targeted delivery of potent PLGA encapsulated 3,3’-diindolylmethane nanoparticles through blood brain barrier prevents glioma progression

https://doi.org/10.18632/oncotarget.18689

Arijit Bhowmik, Sayak Chakravarti, Aparajita Ghosh, Rajni Shaw, Suman Bhandary, Satyaranjan Bhattacharyya, Parimal C. Sen,  and Mrinal K. Ghosh
65339-65358
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

XIST/miR-139 axis regulates bleomycin (BLM)-induced extracellular matrix (ECM) and pulmonary fibrosis through β-catenin

XIST/miR-139 axis regulates bleomycin (BLM)-induced extracellular matrix (ECM) and pulmonary fibrosis through β-catenin

https://doi.org/10.18632/oncotarget.18310

Yichun Wang, Ying Liang, Junming Luo, Jing Nie, Huiming Yin, Qiong Chen, Jing Dong, Jixiang Zhu, Jiamei Xia,  and Wei Shuai
65359-65369
Abstract  |  PDF  |  HTML  |  Order a Reprint

Long non-coding RNA UBE2CP3 promotes tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma

Long non-coding RNA UBE2CP3 promotes tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.18524

Shun-Wang Cao, Jin-Lan Huang, Jing Chen, Yan-Wei Hu, Xiu-Mei Hu, Ting-Yu Ren, Shi-Hao Zheng, Jin-Duan Lin, Jing Tang, Lei Zheng,  and Qian Wang
65370-65385
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Lipocalin 2 regulates intestine bacterial survival by interplaying with siderophore in a weaned piglet model of Escherichia coli infection

Lipocalin 2 regulates intestine bacterial survival by interplaying with siderophore in a weaned piglet model of Escherichia coli infection

https://doi.org/10.18632/oncotarget.18528

Bing-Xiu Guo, Qian-Qian Wang, Jia-Hui Li, Zhen-Shun Gan, Xiao-Feng Zhang, Yi-Zhen Wang,  and Hua-Hua Du
65386-65396
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-149* suppresses hepatic inflammatory response through antagonizing STAT3 signaling pathway

MicroRNA-149* suppresses hepatic inflammatory response through antagonizing STAT3 signaling pathway

https://doi.org/10.18632/oncotarget.18541

Qiqi Zhang, Jia Su, Ziwei Wang, Hui Qi, Zeyong Ge, Zhijun Li, Wei-Dong Chen,  and Yan-Dong Wang
65397-65406
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Colorectal carcinoma with osseous metaplasia

Colorectal carcinoma with osseous metaplasia

https://doi.org/10.18632/oncotarget.18577

Xibo Liu, Jinghong Xu,  and Lirong Chen
65407-65413
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Curcumin protects against hepatic ischemia/reperfusion induced injury through inhibiting TLR4/NF-κB pathway

Curcumin protects against hepatic ischemia/reperfusion induced injury through inhibiting TLR4/NF-κB pathway

https://doi.org/10.18632/oncotarget.18676

Lu Wang, Ning Li, Dongdong Lin,  and Yunjin Zang
65414-65420
Abstract  |  PDF  |  HTML  |  Order a Reprint

Transcriptomic profiling of long non-coding RNAs in hepatitis B virus-related hepatocellular carcinoma

Transcriptomic profiling of long non-coding RNAs in hepatitis B virus-related hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.18897

Hongxia Fan, Qiaoge Zhang, Xiaopei Zhao, Ping Lv, Min Liu,  and Hua Tang
65421-65434
Abstract  |  PDF  |  HTML  |  Order a Reprint

Quantitative evaluation of Gd-EOB-DTPA uptake in focal liver lesions by using T1 mapping: differences between hepatocellular carcinoma, hepatic focal nodular hyperplasia and cavernous hemangioma

Quantitative evaluation of Gd-EOB-DTPA uptake in focal liver lesions by using T1 mapping: differences between hepatocellular carcinoma, hepatic focal nodular hyperplasia and cavernous hemangioma

https://doi.org/10.18632/oncotarget.18918

Zhenpeng Peng, Chang Li, Tao Chan, Huasong Cai, Yanji Luo, Zhi Dong, Zi-Ping Li,  and Shi-Ting Feng
65435-65444
Abstract  |  PDF  |  HTML  |  Order a Reprint

The prohibitin protein complex promotes mitochondrial stabilization and cell survival in hematologic malignancies

The prohibitin protein complex promotes mitochondrial stabilization and cell survival in hematologic malignancies

https://doi.org/10.18632/oncotarget.18920

Jeremy A. Ross, Elisa Robles-Escajeda, Derrick M. Oaxaca, Diana L. Padilla,  and Robert A. Kirken
65445-65456
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-200c increases radiosensitivity of human cancer cells with activated EGFR-associated signaling

MicroRNA-200c increases radiosensitivity of human cancer cells with activated EGFR-associated signaling

https://doi.org/10.18632/oncotarget.18924

Taeryool Koo, Bong Jun Cho, Dan Hyo Kim, Ji Min Park, Eun Jung Choi, Hans H. Kim, David J. Lee,  and In Ah Kim
65457-65468
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A potential prognostic biomarker SPC24 promotes tumorigenesis and metastasis in lung cancer

A potential prognostic biomarker SPC24 promotes tumorigenesis and metastasis in lung cancer

https://doi.org/10.18632/oncotarget.18971

Juan Zhou, Yang Yu, Yunfeng Pei, Chunping Cao, Chen Ding, Duping Wang, Li Sun,  and Guoping Niu
65469-65480
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The association between renal sinus fat area and the progression-free survival in Chinese non-metastatic clear-cell renal cell carcinoma patients

The association between renal sinus fat area and the progression-free survival in Chinese non-metastatic clear-cell renal cell carcinoma patients

https://doi.org/10.18632/oncotarget.19012

Haichao Huang, Shi Chen, Wei Yu, Zirong Ye, Wei Li, Jinchun Xing,  and Xiurong Wu
65481-65491
Abstract  |  PDF  |  HTML  |  Order a Reprint

Risk-stratified surveillance and cost effectiveness of follow-up after radical cystectomy in patients with muscle-invasive bladder cancer

Risk-stratified surveillance and cost effectiveness of follow-up after radical cystectomy in patients with muscle-invasive bladder cancer

https://doi.org/10.18632/oncotarget.19043

Ayumu Kusaka, Shingo Hatakeyama, Shogo Hosogoe, Itsuto Hamano, Hiromichi Iwamura, Naoki Fujita, Ken Fukushi, Takuma Narita, Kazuhisa Hagiwara, Hayato Yamamoto, Yuki Tobisawa, Tohru Yoneyama, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Hiroyuki Ito, Kazuaki Yoshikawa, Toshiaki Kawaguchi,  and Chikara Ohyama
65492-65505
Abstract  |  PDF  |  HTML  |  Order a Reprint

Disrupted small-world brain network topology in pure conduct disorder

Disrupted small-world brain network topology in pure conduct disorder

https://doi.org/10.18632/oncotarget.19098

Feng-Mei Lu, Jian-Song Zhou, Jiang Zhang, Xiao-Ping Wang,  and Zhen Yuan
65506-65524
Abstract  |  PDF  |  HTML  |  Order a Reprint

New insights in the clinical and translational relevance of miR483-5p in adrenocortical cancer

New insights in the clinical and translational relevance of miR483-5p in adrenocortical cancer

https://doi.org/10.18632/oncotarget.19118

Francesca Salvianti, Letizia Canu, Giada Poli, Roberta Armignacco, Cristian Scatena, Giulia Cantini, Alessandra Di Franco, Stefania Gelmini, Tonino Ercolino, Mario Pazzagli, Gabriella Nesi, Massimo Mannelli, Pamela Pinzani,  and Michaela Luconi
65525-65533
Abstract  |  PDF  |  HTML  |  Order a Reprint

Transcriptome analysis reveals a role for the endothelial ANP-GC-A signaling in interfering with pre-metastatic niche formation by solid cancers

Transcriptome analysis reveals a role for the endothelial ANP-GC-A signaling in interfering with pre-metastatic niche formation by solid cancers

https://doi.org/10.18632/oncotarget.18032

Takashi Nojiri, Miki Arai, Yutaka Suzuki, Motofumi Kumazoe, Takeshi Tokudome, Koichi Miura, Jun Hino, Hiroshi Hosoda, Mikiya Miyazato, Meinoshin Okumura, Shinpei Kawaoka,  and Kenji Kangawa
65534-65547
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The H3K27me3-demethylase KDM6A is suppressed in breast cancer stem-like cells, and enables the resolution of bivalency during the mesenchymal-epithelial transition

The H3K27me3-demethylase KDM6A is suppressed in breast cancer stem-like cells, and enables the resolution of bivalency during the mesenchymal-epithelial transition

https://doi.org/10.18632/oncotarget.19214

Joseph H. Taube, Nathalie Sphyris, Kelsey S. Johnson, Keighley N. Reisenauer, Taylor A. Nesbit, Robiya Joseph, Geraldine V. Vijay, Tapasree R. Sarkar, Neeraja A. Bhangre, Joon Jin Song, Jeffrey T. Chang, Min Gyu Lee, Rama Soundararajan,  and Sendurai A. Mani
65548-65565
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PTEN loss detection in prostate cancer: comparison of PTEN immunohistochemistry and PTEN FISH in a large retrospective prostatectomy cohort

PTEN loss detection in prostate cancer: comparison of PTEN immunohistochemistry and PTEN FISH in a large retrospective prostatectomy cohort

https://doi.org/10.18632/oncotarget.19217

Tamara L. Lotan, Asmus Heumann, Sebastian Dwertmann Rico, Jessica Hicks, Kristen Lecksell, Christina Koop, Guido Sauter, Thorsten Schlomm,  and Ronald Simon
65566-65576
Abstract  |  PDF  |  HTML  |  Order a Reprint

Long noncoding RNA AB073614 promotes the malignance of glioma by activating Wnt/β-catenin signaling through downregulating SOX7

Long noncoding RNA AB073614 promotes the malignance of glioma by activating Wnt/β-catenin signaling through downregulating SOX7

https://doi.org/10.18632/oncotarget.19305

Yuqian Li, Gang Zhu, Wen Zeng, Jiancai Wang, Zhihong Li, Bao Wang, Bo Tian, Dan Lu, Xingye Zhang, Guodong Gao,  and Lihong Li
65577-65587
Abstract  |  PDF  |  HTML  |  Order a Reprint

Mobilization studies in mice deficient in sphingosine kinase 2 support a crucial role of the plasma level of sphingosine-1-phosphate in the egress of hematopoietic stem progenitor cells

Mobilization studies in mice deficient in sphingosine kinase 2 support a crucial role of the plasma level of sphingosine-1-phosphate in the egress of hematopoietic stem progenitor cells

https://doi.org/10.18632/oncotarget.19514

Mateusz Adamiak, Lakshman Chelvarajan, Kevin R. Lynch, Webster L. Santos, Ahmed Abdel-Latif,  and Mariusz Z. Ratajczak
65588-65600
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Protein tyrosine phosphatase nonreceptor type 22 (PTPN22) gene single nucleotide polymorphisms and its interaction with T2DM on pulmonary tuberculosis in Chinese Uygur population

Protein tyrosine phosphatase nonreceptor type 22 (PTPN22) gene single nucleotide polymorphisms and its interaction with T2DM on pulmonary tuberculosis in Chinese Uygur population

https://doi.org/10.18632/oncotarget.19274

Xian-Hua Wang, Ai-Guo Ma, Xiu-Xia Han, Lei Chen, Hui Liang, Aishan- Litifu, Abudumijit- Ablez,  and Feng Xue
65601-65608
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic relevance of protein expression, clinical factors, and MYD88 mutation in primary bone lymphoma

Prognostic relevance of protein expression, clinical factors, and MYD88 mutation in primary bone lymphoma

https://doi.org/10.18632/oncotarget.19936

Yong Xu, Jian Li, Jian Ouyang, Juan Li, Jingyan Xu, Qiguo Zhang, Yonggong Yang, Min Zhou, Jing Wang, Cuiling Zhang, Yueyi Xu, Ping Li, Rongfu Zhou,  and Bing Chen
65609-65619
Abstract  |  PDF  |  HTML  |  Order a Reprint

LMO1 polymorphisms reduce neuroblastoma risk in Chinese children: a two-center case-control study

LMO1 polymorphisms reduce neuroblastoma risk in Chinese children: a two-center case-control study

https://doi.org/10.18632/oncotarget.20018

Jiao Zhang, Huiran Lin, Jiaxiang Wang, Jing He, Da Zhang, Pan Qin, Lin Yang,  and Lizhao Yan
65620-65626
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Melatonin promotes the proliferation of GC-1 spg cells by inducing metallothionein-2 expression through ERK1/2 signaling pathway activation

Melatonin promotes the proliferation of GC-1 spg cells by inducing metallothionein-2 expression through ERK1/2 signaling pathway activation

https://doi.org/10.18632/oncotarget.20019

Chunjin Li, Xiaoling Zhu, Shuxiong Chen, Lu Chen, Yun Zhao, Yanwen Jiang, Shan Gao, Fengge Wang, Zhuo Liu, Rong Fan, Liting Sun,  and Xu Zhou
65627-65641
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

VRK1 promotes cisplatin resistance by up-regulating c-MYC via c-Jun activation and serves as a therapeutic target in esophageal squamous cell carcinoma

VRK1 promotes cisplatin resistance by up-regulating c-MYC via c-Jun activation and serves as a therapeutic target in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.20020

Zhen-Chuan Liu, Kuo Cao, Zhao-Hua Xiao, Liang Qiao, Xue-Qing Wang, Bin Shang, Yang Jia,  and Zhou Wang
65642-65658
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value of long non-coding RNA TUG1 in various tumors

Prognostic value of long non-coding RNA TUG1 in various tumors

https://doi.org/10.18632/oncotarget.20025

Na Li, Ke Shi, Xinmei Kang,  and Wei Li
65659-65667
Abstract  |  PDF  |  HTML  |  Order a Reprint

The appropriate number of ELNs for lymph node negative breast cancer patients underwent MRM: a population-based study

The appropriate number of ELNs for lymph node negative breast cancer patients underwent MRM: a population-based study

https://doi.org/10.18632/oncotarget.20052

Huiying Chi, Chenyue Zhang, Haiyong Wang,  and Zhehai Wang
65668-65676
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cystathionine- γ-lyase promotes process of breast cancer in association with STAT3 signaling pathway

Cystathionine- γ-lyase promotes process of breast cancer in association with STAT3 signaling pathway

https://doi.org/10.18632/oncotarget.20057

Jing You, Xiaoyan Shi, Huimin Liang, Juan Ye, Lupeng Wang, Huanxiao Han, Hongyu Fang, Wenyi Kang,  and Tianxiao Wang
65677-65686
Abstract  |  PDF  |  HTML  |  Order a Reprint

MiR-324-3p promotes tumor growth through targeting DACT1 and activation of Wnt/β-catenin pathway in hepatocellular carcinoma

MiR-324-3p promotes tumor growth through targeting DACT1 and activation of Wnt/β-catenin pathway in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.20058

Hang Tuo, Yufeng Wang, Liang Wang, Bowen Yao, Qing Li, Cong Wang, Zhikui Liu, Shaoshan Han, Guozhi Yin, Kangsheng Tu,  and Qingguang Liu
65687-65698
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Alterations in DNA methylation/demethylation intermediates predict clinical outcome in chronic lymphocytic leukemia

Alterations in DNA methylation/demethylation intermediates predict clinical outcome in chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.20081

Cristina Bagacean, Adrian Tempescul, Christelle Le Dantec, Anne Bordron, Audrey Mohr, Hussam Saad, Valerie Olivier, Mihnea Zdrenghea, Victor Cristea, Pierre-François Cartron, Nathalie Douet-Guilbert, Christian Berthou,  and Yves Renaudineau
65699-65716
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A comparative study of anti-aging properties and mechanism: resveratrol and caloric restriction

A comparative study of anti-aging properties and mechanism: resveratrol and caloric restriction

https://doi.org/10.18632/oncotarget.20084

Juan Li, Chun-Xia Zhang, Yi-Mei Liu, Ke-Li Chen,  and Gang Chen
65717-65729
Abstract  |  PDF  |  HTML  |  Order a Reprint

NHERF1 together with PARP1 and BRCA1 expression as a new potential biomarker to stratify breast cancer patients

NHERF1 together with PARP1 and BRCA1 expression as a new potential biomarker to stratify breast cancer patients

https://doi.org/10.18632/oncotarget.19444

Anita Mangia, Emanuela Scarpi, Giulia Partipilo, Laura Schirosi, Giuseppina Opinto, Francesco Giotta,  and Giovanni Simone
65730-65742
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Resveratrol promotes MICA/B expression and natural killer cell lysis of breast cancer cells by suppressing c-Myc/miR-17 pathway

Resveratrol promotes MICA/B expression and natural killer cell lysis of breast cancer cells by suppressing c-Myc/miR-17 pathway

https://doi.org/10.18632/oncotarget.19445

Jie Pan, Jiaying Shen, Wengong Si, Chengyong Du, Danni Chen, Liang Xu, Minya Yao, Peifen Fu,  and Weimin Fan
65743-65758
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic and environmental factors and serum hormones, and risk of estrogen receptor-positive breast cancer in pre- and postmenopausal Japanese women

Genetic and environmental factors and serum hormones, and risk of estrogen receptor-positive breast cancer in pre- and postmenopausal Japanese women

https://doi.org/10.18632/oncotarget.20182

Jiazhi Guo, Aiko Sueta, Koshi Nakamura, Nobuyasu Yoshimoto, Motoi Baba, Naoko Ishida, Kanako Hagio, Tatsuya Toyama, Hirotaka Iwase, Akiko Tamakoshi,  and Hiroko Yamashita
65759-65769
Abstract  |  PDF  |  HTML  |  Order a Reprint

Real-time in vivo imaging of metastatic bone tumors with a targeted near-infrared fluorophore

Real-time in vivo imaging of metastatic bone tumors with a targeted near-infrared fluorophore

https://doi.org/10.18632/oncotarget.20187

Wonbong Lim, HongMoon Sohn, Youngjong Ko, Mineon Park, Bora Kim, Danbi Jo, Jin Seok Jung, Dae Hyeok Yang, Jangho Kim, Ok Joon Kim, Donghwi Kim, Young Lae Moon, Jung-Joon Min,  and Hoon Hyun
65770-65777
Abstract  |  PDF  |  HTML  |  Order a Reprint

Protective effect of resveratrol against light-induced retinal degeneration in aged SAMP8 mice

Protective effect of resveratrol against light-induced retinal degeneration in aged SAMP8 mice

https://doi.org/10.18632/oncotarget.19473

Zhirong Liu, Zhengzheng Wu, Jie Li, Anna Marmalidou, Ruifan Zhang,  and Man Yu
65778-65788
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Up-regulation of brain-expressed X-linked 2 is critical for hepatitis B virus X protein-induced hepatocellular carcinoma development

Up-regulation of brain-expressed X-linked 2 is critical for hepatitis B virus X protein-induced hepatocellular carcinoma development

https://doi.org/10.18632/oncotarget.19477

Fuqiang Huang, Pei Cai, Yanan Wang, Xian Zhou, Hongyu Chen, Wenjun Liao, Yilei Mao, Xiaojun Zha, Hongbing Zhang,  and Zhongdong Hu
65789-65799
Abstract  |  PDF  |  HTML  |  Order a Reprint

NBPF7 promotes the proliferation of α-catenin-knockdown HaCaT cells via functional interaction with the NF-κB pathway

NBPF7 promotes the proliferation of α-catenin-knockdown HaCaT cells via functional interaction with the NF-κB pathway

https://doi.org/10.18632/oncotarget.19480

Hua-Yu Zhu, Wen-Dong Bai, Chao Li, Jun Li,  and Da-Hai Hu
65800-65808
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Regulatory actions of ToxR and CalR on their own genes and type III secretion system 1 in Vibrio parahaemolyticus

Regulatory actions of ToxR and CalR on their own genes and type III secretion system 1 in Vibrio parahaemolyticus

https://doi.org/10.18632/oncotarget.19498

George Osei-Adjei, He Gao, Ying Zhang, Lingyu Zhang, Wenhui Yang, Huiying Yang, Zhe Yin, Xinxiang Huang, Yiquan Zhang,  and Dongsheng Zhou
65809-65822
Abstract  |  PDF  |  HTML  |  Order a Reprint

The prognostic potential and carcinogenesis of long non-coding RNA TUG1 in human cholangiocarcinoma

The prognostic potential and carcinogenesis of long non-coding RNA TUG1 in human cholangiocarcinoma

https://doi.org/10.18632/oncotarget.19502

Yi Xu, Kaiming Leng, Zhenglong Li, Fumin Zhang, Xiangyu Zhong, Pengcheng Kang, Xingming Jiang,  and Yunfu Cui
65823-65835
Abstract  |  PDF  |  HTML  |  Order a Reprint

Contrastive study of two screening criteria for active surveillance in patients with low-risk papillary thyroid microcarcinoma: a retrospective analysis of 1001 patients

Contrastive study of two screening criteria for active surveillance in patients with low-risk papillary thyroid microcarcinoma: a retrospective analysis of 1001 patients

https://doi.org/10.18632/oncotarget.19503

Kai Qian, Kai Guo, Xiaoke Zheng, Tuanqi Sun, Duanshu Li, Yi Wu, Qinghai Ji,  and Zhuoying Wang
65836-65846
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Coexpression analysis identifies nuclear reprogramming barriers of somatic cell nuclear transfer embryos

Coexpression analysis identifies nuclear reprogramming barriers of somatic cell nuclear transfer embryos

https://doi.org/10.18632/oncotarget.19504

Yongchun Zuo, Guanghua Su, Lei Cheng, Kun Liu, Yu Feng, Zhuying Wei, Chunling Bai, Guifang Cao,  and Guangpeng Li
65847-65859
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Effects of exercise on capillaries in the white matter of transgenic AD mice

Effects of exercise on capillaries in the white matter of transgenic AD mice

https://doi.org/10.18632/oncotarget.19505

Yi Zhang, Feng-Lei Chao, Chun-Ni Zhou, Lin Jiang, Lei Zhang, Lin-Mu Chen, Yan-Min Luo, Qian Xiao,  and Yong Tang
65860-65875
Abstract  |  PDF  |  HTML  |  Order a Reprint

The genetically engineered drug rhCNB induces apoptosis via a mitochondrial route in tumor cells

The genetically engineered drug rhCNB induces apoptosis via a mitochondrial route in tumor cells

https://doi.org/10.18632/oncotarget.19507

Yang Yang, Huan Yang, Jinju Yang, Li Li, Benqiong Xiang,  and Qun Wei
65876-65888
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Small molecule CP-31398 induces reactive oxygen species-dependent apoptosis in human multiple myeloma

Small molecule CP-31398 induces reactive oxygen species-dependent apoptosis in human multiple myeloma

https://doi.org/10.18632/oncotarget.19508

Yohei Arihara, Kohichi Takada, Yusuke Kamihara, Naotaka Hayasaka, Hajime Nakamura, Kazuyuki Murase, Hiroshi Ikeda, Satoshi Iyama, Tsutomu Sato, Koji Miyanishi, Masayoshi Kobune,  and Junji Kato
65889-65899
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cell cycle specific radiosensitisation by the disulfiram and copper complex

Cell cycle specific radiosensitisation by the disulfiram and copper complex

https://doi.org/10.18632/oncotarget.19539

Mathias Tesson, Giorgio Anselmi, Caitlin Bell,  and Robert Mairs
65900-65916
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

In vivo immuno-targeting of an extracellular epitope of membrane bound preferentially expressed antigen in melanoma (PRAME)

In vivo immuno-targeting of an extracellular epitope of membrane bound preferentially expressed antigen in melanoma (PRAME)

https://doi.org/10.18632/oncotarget.19579

Dmitry Pankov, Ludvig Sjöström, Teja Kalidindi, Sang-Gyu Lee, Kjell Sjöström, Rui Gardner, Michael R. McDevitt, Richard O’Reilly, Daniel L.J. Thorek, Steven M. Larson, Darren Veach,  and David Ulmert
65917-65931
Abstract  |  PDF  |  HTML  |  Order a Reprint

The long noncoding RNA TUG1 acts as a competing endogenous RNA to regulate the Hedgehog pathway by targeting miR-132 in hepatocellular carcinoma

The long noncoding RNA TUG1 acts as a competing endogenous RNA to regulate the Hedgehog pathway by targeting miR-132 in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.19582

Jingjing Li, Qinghui Zhang, Xiaoming Fan, Wenhui Mo, Weiqi Dai, Jiao Feng, Liwei Wu, Tong Liu, Sainan Li, Shizan Xu, Wenwen Wang, Xiya Lu, Qiang Yu, Kan Chen, Yujing Xia, Jie Lu, Yingqun Zhou, Ling Xu,  and Chuanyong Guo
65932-65945
Abstract  |  PDF  |  HTML  |  Order a Reprint

YBX1 promotes tumor growth by elevating glycolysis in human bladder cancer

YBX1 promotes tumor growth by elevating glycolysis in human bladder cancer

https://doi.org/10.18632/oncotarget.19583

Liuyu Xu, Hongyun Li, Longchao Wu,  and Shiming Huang
65946-65956
Abstract  |  PDF  |  HTML  |  Order a Reprint

FZD7 is a novel prognostic marker and promotes tumor metastasis via WNT and EMT signaling pathways in esophageal squamous cell carcinoma

FZD7 is a novel prognostic marker and promotes tumor metastasis via WNT and EMT signaling pathways in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.19586

Ting-Ting Cao, Di Xiang, Bei-Lei Liu, Tu-Xiong Huang, Bin-Bin Tan, Chui-Mian Zeng, Zhong-Yuan Wang, Xiao-Yan Ming, Li-Yi Zhang, Guangyi Jin, Feng Li, Jian-Lin Wu, Xin-Yuan Guan, Desheng Lu,  and Li Fu
65957-65968
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

EGF stimulates glioblastoma metastasis by induction of matrix metalloproteinase-9 in an EGFR-dependent mechanism

EGF stimulates glioblastoma metastasis by induction of matrix metalloproteinase-9 in an EGFR-dependent mechanism

https://doi.org/10.18632/oncotarget.19622

Xing-Chen Chen, Xiang-Tai Wei, Jun-Hong Guan, Hong Shu,  and Duo Chen
65969-65982
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Prognostic factors and outcomes of primary transitional cell carcinoma of the ureter: a population-based study

Prognostic factors and outcomes of primary transitional cell carcinoma of the ureter: a population-based study

https://doi.org/10.18632/oncotarget.19623

Tao Ding, Zhuojun Zheng, Renfang Xu,  and Cuixing Zhou
65983-65996
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Integrated analysis of competing endogenous RNA network revealing lncRNAs as potential prognostic biomarkers in human lung squamous cell carcinoma

Integrated analysis of competing endogenous RNA network revealing lncRNAs as potential prognostic biomarkers in human lung squamous cell carcinoma

https://doi.org/10.18632/oncotarget.19627

Jing Sui, Si-Yi Xu, Jiali Han, Song-Ru Yang, Cheng-Yun Li, Li-Hong Yin, Yue-Pu Pu,  and Ge-Yu Liang
65997-66018
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Similar response profile to neoadjuvant chemotherapy, but different survival, in inflammatory versus locally advanced breast cancers

Similar response profile to neoadjuvant chemotherapy, but different survival, in inflammatory versus locally advanced breast cancers

https://doi.org/10.18632/oncotarget.19732

Audrey Monneur, Anthony Goncalves, Marine Gilabert, Pascal Finetti, Carole Tarpin, Christophe Zemmour, Jean-Marc Extra, Agnès Tallet, Eric Lambaudie, Jocelyne Jacquemier, Gilles Houvenaeghel, Jean-Marie Boher, Patrice Viens,  and François Bertucci
66019-66032
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

7-ketocholesterol and 27-hydroxycholesterol decreased doxorubicin sensitivity in breast cancer cells: estrogenic activity and mTOR pathway

7-ketocholesterol and 27-hydroxycholesterol decreased doxorubicin sensitivity in breast cancer cells: estrogenic activity and mTOR pathway

https://doi.org/10.18632/oncotarget.19789

Chun-Wei Wang, Chiung-Chiao Huang, Pei-Hsin Chou, Yu-Ping Chang, Shouzuo Wei, Frederick Peter Guengerich, Yueh-Ching Chou, Sheng-Fan Wang, Ping-Shan Lai, Pavel Souček,  and Yune-Fang Ueng
66033-66050
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

BMI and serum lipid parameters predict increasing risk and aggressive prostate cancer in Chinese people

BMI and serum lipid parameters predict increasing risk and aggressive prostate cancer in Chinese people

https://doi.org/10.18632/oncotarget.19790

Ruizhe Zhao, Gong Cheng, Bing Wang, Chao Qin, Yun Liu, Yongsheng Pan, Jun Wang, Lixin Hua, Weidong Zhu,  and Zengjun Wang
66051-66060
Abstract  |  PDF  |  HTML  |  Order a Reprint

GATA2 regulates the erythropoietin receptor in t(12;21) ALL

GATA2 regulates the erythropoietin receptor in t(12;21) ALL

https://doi.org/10.18632/oncotarget.19792

Marie E. Gaine, Daniel J. Sharpe, James S. Smith, Hilary A.A. Colyer, Vivien M. Hodges, Terry R. Lappin,  and Ken I. Mills
66061-66074
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Systemic immune-inflammation index predicts the clinical outcome in patients with nasopharyngeal carcinoma: a propensity score-matched analysis

Systemic immune-inflammation index predicts the clinical outcome in patients with nasopharyngeal carcinoma: a propensity score-matched analysis

https://doi.org/10.18632/oncotarget.19796

Wenjie Jiang, Yuan Chen, Jin Huang, Dan Xi, Jun Chen, Yingjie Shao, Guoping Xu, Wenming Ying, Jun Wei, Junjun Chen, Zhonghua Ning, Wendong Gu,  and Honglei Pei
66075-66086
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KRAS overexpression independent of RAS mutations confers an adverse prognosis in cytogenetically normal acute myeloid leukemia

KRAS overexpression independent of RAS mutations confers an adverse prognosis in cytogenetically normal acute myeloid leukemia

https://doi.org/10.18632/oncotarget.19798

Jing-Dong Zhou, Dong-Ming Yao, Xi-Xi Li, Ting-Juan Zhang, Wei Zhang, Ji-Chun Ma, Hong Guo, Zhao-Qun Deng, Jiang Lin,  and Jun Qian
66087-66097
Abstract  |  PDF  |  HTML  |  Order a Reprint

Metadherin promotes metastasis by supporting putative cancer stem cell properties and epithelial plasticity in pancreatic cancer

Metadherin promotes metastasis by supporting putative cancer stem cell properties and epithelial plasticity in pancreatic cancer

https://doi.org/10.18632/oncotarget.19802

Kensuke Suzuki, Shigetsugu Takano, Hideyuki Yoshitomi, Hitoe Nishino, Shingo Kagawa, Hiroaki Shimizu, Katsunori Furukawa, Masaru Miyazaki,  and Masayuki Ohtsuka
66098-66111
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

177Lu-PSMA-617 radioligand therapy for a patient with lymph node metastatic prostate cancer

177Lu-PSMA-617 radioligand therapy for a patient with lymph node metastatic prostate cancer

https://doi.org/10.18632/oncotarget.19805

Finn E. von Eyben, Timo Kiljunen, Timo Joensuu, Kalevi Kairemo, Christian Uprimny,  and Irene Virgolini
66112-66116
Abstract  |  PDF  |  HTML  |  Order a Reprint

Kras mutation is a marker of worse oncologic outcomes after percutaneous radiofrequency ablation of colorectal liver metastases

Kras mutation is a marker of worse oncologic outcomes after percutaneous radiofrequency ablation of colorectal liver metastases

https://doi.org/10.18632/oncotarget.19806

Waleed Shady, Elena N. Petre, Efsevia Vakiani, Etay Ziv, Mithat Gonen, Karen T. Brown, Nancy E. Kemeny, Stephen B. Solomon, David B. Solit,  and Constantinos T. Sofocleous
66117-66127
Abstract  |  PDF  |  HTML  |  Order a Reprint

Diffusion-kurtosis imaging predicts early radiotherapy response in nasopharyngeal carcinoma patients

Diffusion-kurtosis imaging predicts early radiotherapy response in nasopharyngeal carcinoma patients

https://doi.org/10.18632/oncotarget.19820

Gang Wu, Meng-Meng Li, Feng Chen, Shao-Ming Lin, Kai Yang, Ying-Man Zhao, Xiao-Lei Zhu, Wei-Yuan Huang,  and Jian-Jun Li
66128-66136
Abstract  |  PDF  |  HTML  |  Order a Reprint

Generation and characterization of ErbB2-CAR-engineered cytokine-induced killer cells for the treatment of high-risk soft tissue sarcoma in children

Generation and characterization of ErbB2-CAR-engineered cytokine-induced killer cells for the treatment of high-risk soft tissue sarcoma in children

https://doi.org/10.18632/oncotarget.19821

Michael Merker, Verena Pfirrmann, Sarah Oelsner, Simone Fulda, Thomas Klingebiel, Winfried S. Wels, Peter Bader,  and Eva Rettinger
66137-66153
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

EDG2 enhanced the progression of hepatocellular carcinoma by LPA/PI3K/AKT/ mTOR signaling

EDG2 enhanced the progression of hepatocellular carcinoma by LPA/PI3K/AKT/ mTOR signaling

https://doi.org/10.18632/oncotarget.19825

Meng Xu, Zhikui Liu, Cong Wang, Bowen Yao,  and Xin Zheng
66154-66168
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metformin and endometrial cancer survival: a quantitative synthesis of observational studies

Metformin and endometrial cancer survival: a quantitative synthesis of observational studies

https://doi.org/10.18632/oncotarget.19830

Jianfeng Guo, Kai Xu, Min An,  and Yingchao Zhao
66169-66177
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinicopathologic implications of the miR-197/PD-L1 axis in oral squamous cell carcinoma

Clinicopathologic implications of the miR-197/PD-L1 axis in oral squamous cell carcinoma

https://doi.org/10.18632/oncotarget.19842

Hyein Ahn, Jeong Mi Yang, Hyojin Kim, Jin-Haeng Chung, Soon-Hyun Ahn, Woo-Jin Jeong,  and Jin Ho Paik
66178-66194
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Slingshot-1L, a cofilin phosphatase, induces primary breast cancer metastasis

Slingshot-1L, a cofilin phosphatase, induces primary breast cancer metastasis

https://doi.org/10.18632/oncotarget.19855

Chen Chen, Yusufu Maimaiti, Shen Zhijun, Liu Zeming, Guo Yawen, Yu Pan,  and Huang Tao
66195-66203
Abstract  |  PDF  |  HTML  |  Order a Reprint

Interleukin 10 gene rs1800896 polymorphism is associated with the risk of prostate cancer

Interleukin 10 gene rs1800896 polymorphism is associated with the risk of prostate cancer

https://doi.org/10.18632/oncotarget.19857

Hao Chen, Jilei Tang, Nan Shen,  and Kewei Ren
66204-66214
Abstract  |  PDF  |  HTML  |  Order a Reprint

The deubiquitinating enzyme USP5 promotes pancreatic cancer via modulating cell cycle regulators

The deubiquitinating enzyme USP5 promotes pancreatic cancer via modulating cell cycle regulators

https://doi.org/10.18632/oncotarget.19882

Brajesh P. Kaistha, Anja Krattenmacher, Johannes Fredebohm, Harald Schmidt, Diana Behrens, Miriam Widder, Thilo Hackert, Oliver Strobel, Jörg D. Hoheisel, Thomas M. Gress,  and Malte Buchholz
66215-66225
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Bitter melon extract inhibits breast cancer growth in preclinical model by inducing autophagic cell death

Bitter melon extract inhibits breast cancer growth in preclinical model by inducing autophagic cell death

https://doi.org/10.18632/oncotarget.19887

Naoshad Muhammad, Robert Steele, Scott T. Isbell, Nancy Philips,  and Ratna B. Ray
66226-66236
Abstract  |  PDF  |  HTML  |  Order a Reprint

PIK3CA amplification and PTEN loss in diffused large B-cell lymphoma

PIK3CA amplification and PTEN loss in diffused large B-cell lymphoma

https://doi.org/10.18632/oncotarget.19889

Wenli Cui, Mingfu Ma, Shutao Zheng, Zhiping Ma, Liping Su,  and Wei Zhang
66237-66247
Abstract  |  PDF  |  HTML  |  Order a Reprint

Efficiency of low dosage apatinib in post-first-line treatment of advanced lung adenocarcinoma

Efficiency of low dosage apatinib in post-first-line treatment of advanced lung adenocarcinoma

https://doi.org/10.18632/oncotarget.19908

Da-Xiong Zeng, Chang-Guo Wang, Wei Lei, Jian-An Huang,  and Jun-Hong Jiang
66248-66253
Abstract  |  PDF  |  HTML  |  Order a Reprint

Establishment of oral squamous cell carcinoma cell line and magnetic bead-based isolation and characterization of its CD90/CD44 subpopulations

Establishment of oral squamous cell carcinoma cell line and magnetic bead-based isolation and characterization of its CD90/CD44 subpopulations

https://doi.org/10.18632/oncotarget.19914

Marketa Svobodova, Martina Raudenska, Jaromir Gumulec, Jan Balvan, Michaela Fojtu, Monika Kratochvilova, Hana Polanska, Zuzana Horakova, Rom Kostrica, Petr Babula, Zbynek Heger,  and Michal Masarik
66254-66269
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Adenovirus-mediated delivery of Sema3A alleviates rheumatoid arthritis in a serum-transfer induced mouse model

Adenovirus-mediated delivery of Sema3A alleviates rheumatoid arthritis in a serum-transfer induced mouse model

https://doi.org/10.18632/oncotarget.19915

Yue Teng, Zhanhai Yin, Jing Li, Kun Li, Xu Li,  and Yan Zhang
66270-66280
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mesenchymal stromal cells promote B-cell lymphoma in lacrimal glands by inducing immunosuppressive microenvironment

Mesenchymal stromal cells promote B-cell lymphoma in lacrimal glands by inducing immunosuppressive microenvironment

https://doi.org/10.18632/oncotarget.19971

Min Joung Lee, Se Yeon Park, Jung Hwa Ko, Hyun Ju Lee, Jin Suk Ryu, Jong Woo Park, Sang In Khwarg, Sun-Ok Yoon,  and Joo Youn Oh
66281-66292
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PD-L1 expression indicates favorable prognosis for advanced lung adenocarcinoma patients treated with pemetrexed

PD-L1 expression indicates favorable prognosis for advanced lung adenocarcinoma patients treated with pemetrexed

https://doi.org/10.18632/oncotarget.19973

Pei Zhang, Zhang Bao, Liming Xu, Jianya Zhou, Guohua Lu, Yinan Yao, Rong Liu, Qiqi Gao, Yihong Shen,  and Jianying Zhou
66293-66304
Abstract  |  PDF  |  HTML  |  Order a Reprint

Development of mesenchymal subtype gene signature for clinical application in gastric cancer

Development of mesenchymal subtype gene signature for clinical application in gastric cancer

https://doi.org/10.18632/oncotarget.19985

Jeeyun Lee, Razvan Cristescu, Kyoung-Mee Kim, Kyung Kim, Seung Tae Kim, Se Hoon Park,  and Won Ki Kang
66305-66315
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting of CCN2 suppresses tumor progression and improves chemo-sensitivity in urothelial bladder cancer

Targeting of CCN2 suppresses tumor progression and improves chemo-sensitivity in urothelial bladder cancer

https://doi.org/10.18632/oncotarget.19987

Xiaojing Wang, Tianyuan Xu, Fengbin Gao, Hongchao He, Yu Zhu,  and Zhoujun Shen
66316-66327
Abstract  |  PDF  |  HTML  |  Order a Reprint

Discovery of NKCC1 as a potential therapeutic target to inhibit hepatocellular carcinoma cell growth and metastasis

Discovery of NKCC1 as a potential therapeutic target to inhibit hepatocellular carcinoma cell growth and metastasis

https://doi.org/10.18632/oncotarget.20240

Yaya Zhou, Wei Sun, Ning Chen, Chen Xu, Xinxin Wang, Kun Dong, Binxue Zhang, Jian Zhang, Ning Hao, Aihua Sun, Handong Wei, Fuchu He,  and Ying Jiang
66328-66342
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Meta-Analysis

The prognostic role of Sirt1 expression in solid malignancies: a meta-analysis

The prognostic role of Sirt1 expression in solid malignancies: a meta-analysis

https://doi.org/10.18632/oncotarget.18494

Changwen Wang, Wen Yang, Fang Dong, Yawen Guo, Jie Tan, Shengnan Ruan,  and Tao Huang
66343-66351
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value of HPV DNA status in cervical cancer before treatment: a systematic review and meta-analysis

Prognostic value of HPV DNA status in cervical cancer before treatment: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.18558

Ping Li, Yue Tan, Li-Xia Zhu, Li-Na Zhou, Ping Zeng, Qin Liu, Min-Bin Chen,  and Ye Tian
66352-66359
Abstract  |  PDF  |  HTML  |  Order a Reprint

Meta-analysis of the clinical characteristics and prognostic relevance of NOTCH1 and FBXW7 mutation in T-cell acute lymphoblastic leukemia

Meta-analysis of the clinical characteristics and prognostic relevance of NOTCH1 and FBXW7 mutation in T-cell acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.18576

Rong-Bin Liu, Jian-Gui Guo, Tian-Ze Liu, Cheng-Cheng Guo, Xin-Xiang Fan, Xiao Zhang, Wei-Han Hu,  and Xiu-Yu Cai
66360-66370
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic polymorphisms in human UDP-glucuronosyltransferases 1A7 and the risk of gastrointestinal carcinomas: A systematic review and network meta-analysis

Genetic polymorphisms in human UDP-glucuronosyltransferases 1A7 and the risk of gastrointestinal carcinomas: A systematic review and network meta-analysis

https://doi.org/10.18632/oncotarget.18675

Yingshi Zhang, Jun Hou, Fan Feng, Dandan Li, Qiyu Jiang, Xiaojuan Li, Qingchun Zhao,  and Bo-An Li
66371-66381
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic role of intratumoral IL-17A expression by immunohistochemistry in solid tumors: a meta-analysis

Prognostic role of intratumoral IL-17A expression by immunohistochemistry in solid tumors: a meta-analysis

https://doi.org/10.18632/oncotarget.18807

Shimin Wang, Zhi’an Li,  and Guoming Hu
66382-66391
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Contrast-enhanced endoscopic ultrasound for differential diagnosis of pancreatic cancer: an updated meta-analysis

Contrast-enhanced endoscopic ultrasound for differential diagnosis of pancreatic cancer: an updated meta-analysis

https://doi.org/10.18632/oncotarget.18915

Xing-Kang He, Yue Ding,  and Lei-Min Sun
66392-66401
Abstract  |  PDF  |  HTML  |  Order a Reprint

Circulating miRNAs as novel diagnostic biomarkers in hepatocellular carcinoma detection: a meta-analysis based on 24 articles

Circulating miRNAs as novel diagnostic biomarkers in hepatocellular carcinoma detection: a meta-analysis based on 24 articles

https://doi.org/10.18632/oncotarget.18949

Yan Ding, Jia-Lai Yan, An-Ning Fang, Wei-Feng Zhou,  and Ling Huang
66402-66413
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Systematic review and meta-analysis of the utility of long non-coding RNA GAS5 as a diagnostic and prognostic cancer biomarker

Systematic review and meta-analysis of the utility of long non-coding RNA GAS5 as a diagnostic and prognostic cancer biomarker

https://doi.org/10.18632/oncotarget.19040

Wei Li, Na Li, Ke Shi,  and Qiong Chen
66414-66425
Abstract  |  PDF  |  HTML  |  Order a Reprint

Comparative efficacy and safety of antibody induction therapy for the treatment of kidney: a network meta-analysis

Comparative efficacy and safety of antibody induction therapy for the treatment of kidney: a network meta-analysis

https://doi.org/10.18632/oncotarget.19815

Mingjie Shao, Tingting Tian, Xinyan Zhu, Yingzi Ming, Yasuko Iwakiri, Shaojun Ye,  and Qifa Ye
66426-66437
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association between air pollution and cardiovascular mortality in China: a systematic review and meta-analysis

Association between air pollution and cardiovascular mortality in China: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.20090

Lei Zhao, Heng-Rui Liang, Feng-Ying Chen, Zi Chen, Wei-Jie Guan,  and Jian-Hua Li
66438-66448
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Percutaneous coronary intervention using drug-eluting stents versus coronary artery bypass graft surgery in left main coronary artery disease an updated meta-analysis of randomized clinical trials

Percutaneous coronary intervention using drug-eluting stents versus coronary artery bypass graft surgery in left main coronary artery disease an updated meta-analysis of randomized clinical trials

https://doi.org/10.18632/oncotarget.20142

Lei Gao, Yuqi Liu, Zhijun Sun, Yabin Wang, Feng Cao,  and Yundai Chen
66449-66457
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeted first-line therapies for advanced colorectal cancer: a Bayesian meta-analysis

Targeted first-line therapies for advanced colorectal cancer: a Bayesian meta-analysis

https://doi.org/10.18632/oncotarget.20185

Yassine Ridouane, Gilberto Lopes, Geoffrey Ku, Hasan Masud,  and Benjamin Haaland
66458-66466
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Loss of heterozygosity on chromosome 16q increases relapse risk in Wilms’ tumor: a meta-analysis

Loss of heterozygosity on chromosome 16q increases relapse risk in Wilms’ tumor: a meta-analysis

https://doi.org/10.18632/oncotarget.20191

Zhenyu Pan, Hairong He, Lina Tang, Qingting Bu, Hua Cheng, Anmin Wang, Jun Lyu,  and Haisheng You
66467-66475
Abstract  |  PDF  |  HTML  |  Order a Reprint

The roles of maspin expression in gastric cancer: a meta- and bioinformatics analysis

The roles of maspin expression in gastric cancer: a meta- and bioinformatics analysis

https://doi.org/10.18632/oncotarget.20192

Hua-Chuan Zheng,  and Bao-Cheng Gong
66476-66490
Abstract  |  PDF  |  HTML  |  Order a Reprint

Which treatment is preferred for advanced non-small-cell lung cancer with wild-type epidermal growth factor receptor in second-line therapy? A meta-analysis comparing immune checkpoint inhibitor, tyrosine kinase inhibitor and chemotherapy

Which treatment is preferred for advanced non-small-cell lung cancer with wild-type epidermal growth factor receptor in second-line therapy? A meta-analysis comparing immune checkpoint inhibitor, tyrosine kinase inhibitor and chemotherapy

https://doi.org/10.18632/oncotarget.20281

Di Wu, Chongyang Duan, Fenfang Wu, Liyong Chen,  and Size Chen
66491-66503
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Efficacy and safety of pramlintide injection adjunct to insulin therapy in patients with type 1 diabetes mellitus: a systematic review and meta-analysis

Efficacy and safety of pramlintide injection adjunct to insulin therapy in patients with type 1 diabetes mellitus: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.16008

Yong-Chao Qiao, Wei Ling, Yan-Hong Pan, Yin-Ling Chen, Dan Zhou, Yan-Mei Huang, Xiao-Xi Zhang,  and Hai-Lu Zhao
66504-66515
Abstract  |  PDF  |  HTML  |  Order a Reprint

11C-choline PET/CT and whole-body MRI including diffusion-weighted imaging for patients with recurrent prostate cancer

11C-choline PET/CT and whole-body MRI including diffusion-weighted imaging for patients with recurrent prostate cancer

https://doi.org/10.18632/oncotarget.16227

Hinrich Wieder, Ambros J. Beer, Konstantin Holzapfel, Martin Henninger, Tobias Maurer, Sarah Schwarzenboeck, Ernst J. Rummeny, Matthias Eiber,  and Jens Stollfuss
66516-66527
Abstract  |  PDF  |  HTML  |  Order a Reprint

The immune impact of mimic endoscopic retrograde appendicitis therapy and appendectomy on rabbits of acute appendicitis

The immune impact of mimic endoscopic retrograde appendicitis therapy and appendectomy on rabbits of acute appendicitis

https://doi.org/10.18632/oncotarget.16236

Suqin Liu, Fenghua Pei, Xinhong Wang, Deliang Li, Lixia Zhao, Yanyan Song, Zhendong Chen,  and Bingrong Liu
66528-66539
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Is preoperative chronic kidney disease status associated with oncologic outcomes in upper urinary tract urothelial carcinoma? A multicenter propensity score-matched analysis

Is preoperative chronic kidney disease status associated with oncologic outcomes in upper urinary tract urothelial carcinoma? A multicenter propensity score-matched analysis

https://doi.org/10.18632/oncotarget.16239

Ho Song Yu, Jun Eul Hwang, Ho Seok Chung, Yang Hyun Cho, Myung Soo Kim, Eu Chang Hwang, Kyung Jin Oh, Sun-Ouck Kim, Seung Il Jung, Taek Won Kang, Dong Deuk Kwon, Kwangsung Park, Soo Bang Ryu, Sung‑Hoon Jung, Young Hoe Hur, Joon Hwa Noh, Myung Ki Kim, Ill Young Seo, Chul-Sung Kim, Sung Gu Kang, Seok Ho Kang,  and Jun Cheon
66540-66549
Abstract  |  PDF  |  HTML  |  Order a Reprint

Leucine-rich alpha-2-glycoprotein-1, relevant with microvessel density, is an independent survival prognostic factor for stage III colorectal cancer patients: a retrospective analysis

Leucine-rich alpha-2-glycoprotein-1, relevant with microvessel density, is an independent survival prognostic factor for stage III colorectal cancer patients: a retrospective analysis

https://doi.org/10.18632/oncotarget.16289

De-Cong Sun, Yan Shi, Ling-Xiong Wang, Yao Lv, Quan-Li Han, Zhi-Kuan Wang,  and Guang-Hai Dai
66550-66558
Abstract  |  PDF  |  HTML  |  Order a Reprint

The optimal chemotherapeutic regimen in D2-resected locally advanced gastric cancer: a propensity score-matched analysis

The optimal chemotherapeutic regimen in D2-resected locally advanced gastric cancer: a propensity score-matched analysis

https://doi.org/10.18632/oncotarget.16301

Jun Eul Hwang, Myung Seo Ki, Karham Kim, Sung-Hoon Jung, Hyun-Jeong Shim, Woo-Kyun Bae, Eu-Chang Hwang, Young Hoe Hur, Oh Jeong, Seong Yeob Ryu, Young Kyu Park, Sang-Hee Cho, Ju-Seog Lee,  and Ik-Joo Chung
66559-66568
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The synergistic effect of dual use of amphetamine-type stimulants and ketamine on drug-induced psychotic symptoms in Chinese synthetic drug users

The synergistic effect of dual use of amphetamine-type stimulants and ketamine on drug-induced psychotic symptoms in Chinese synthetic drug users

https://doi.org/10.18632/oncotarget.16474

Xue-Bing Liu, Yao Zhang, Xu-Yi Wang,  and Wei Hao
66569-66575
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Visceral pleural invasion predict a poor survival among lung adenocarcinoma patients with tumor size ≤ 3cm

Visceral pleural invasion predict a poor survival among lung adenocarcinoma patients with tumor size ≤ 3cm

https://doi.org/10.18632/oncotarget.16476

Tianxiang Chen, Jizhuang Luo, Rui Wang, Haiyong Gu, Yu Gu, Qingyuan Huang, Yiyang Wang, Jiajie Zheng, Chang Gu, Xufeng Pan, Jun Yang, Yunhai Yang,  and Heng Zhao
66576-66583
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Therapeutic evaluation of arterio-portal fistula-related gastroesophageal variceal bleeding

Therapeutic evaluation of arterio-portal fistula-related gastroesophageal variceal bleeding

https://doi.org/10.18632/oncotarget.16579

Xiaoquan Huang, Wen Zhang, Shiyao Chen, Chengfeng Liu, Ruofan Sheng, Feng Li, Jian Wang, Jianjun Luo,  and Pengju Xu
66584-66592
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Timing of chemotherapy-induced neutropenia: the prognostic factor in advanced pancreatic cancer patients treated with gemcitabine / gemcitabine-based chemotherapy

Timing of chemotherapy-induced neutropenia: the prognostic factor in advanced pancreatic cancer patients treated with gemcitabine / gemcitabine-based chemotherapy

https://doi.org/10.18632/oncotarget.16980

Yang Chen, Yan Shi, Huan Yan, Yan Rong Wang,  and Guang Hai Dai
66593-66600
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Reviews

Cancer and the kidney: dangereoux liasons or price paid for the progress in medicine?

Cancer and the kidney: dangereoux liasons or price paid for the progress in medicine?

https://doi.org/10.18632/oncotarget.18094

Jolanta Małyszko, Leszek Kozlowski, Klaudia Kozłowska, Maciej Małyszko,  and Jacek Małyszko
66601-66619
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Comprehensive analysis on diagnostic value of circulating miRNAs for patients with ovarian cancer

Comprehensive analysis on diagnostic value of circulating miRNAs for patients with ovarian cancer

https://doi.org/10.18632/oncotarget.18129

Huiqing Wang, Tingting Wang, Wenpei Shi, Yuan Liu, Lizhang Chen,  and Zhanzhan Li
66620-66628
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The miR-200 family in ovarian cancer

The miR-200 family in ovarian cancer

https://doi.org/10.18632/oncotarget.18343

Maria Koutsaki, Massimo Libra, Demetrios A. Spandidos,  and Apostolos Zaravinos
66629-66640
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Melflufen - a peptidase-potentiated alkylating agent in clinical trials

Melflufen - a peptidase-potentiated alkylating agent in clinical trials

https://doi.org/10.18632/oncotarget.18420

Malin Wickström, Peter Nygren, Rolf Larsson, Johan Harmenberg, Jakob Lindberg, Per Sjöberg, Markus Jerling, Fredrik Lehmann, Paul Richardson, Kenneth Anderson, Dharminder Chauhan,  and Joachim Gullbo
66641-66655
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The role of toll-like receptor 4 in tumor microenvironment

The role of toll-like receptor 4 in tumor microenvironment

https://doi.org/10.18632/oncotarget.19105

Jing Li, Fan Yang, Feng Wei,  and Xiubao Ren
66656-66667
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Bladder cancer stem cells: clonal origin and therapeutic perspectives

Bladder cancer stem cells: clonal origin and therapeutic perspectives

https://doi.org/10.18632/oncotarget.19112

Yi Li, Kaisu Lin, Zhao Yang, Ning Han, Xiaofang Quan, Xiangyang Guo,  and Chong Li
66668-66679
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Nanoformulations of curcumin: an emerging paradigm for improved remedial application

Nanoformulations of curcumin: an emerging paradigm for improved remedial application

https://doi.org/10.18632/oncotarget.19164

Meeta Gera, Neelesh Sharma, Mrinmoy Ghosh, Do Luong Huynh, Sung Jin Lee, Taesun Min, Taeho Kwon,  and Dong Kee Jeong
66680-66698
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Antiangiogenic agents after first line and sorafenib plus chemoembolization: a systematic review

Antiangiogenic agents after first line and sorafenib plus chemoembolization: a systematic review

https://doi.org/10.18632/oncotarget.19449

Andrea Casadei Gardini, Daniele Santini, Giuseppe Aprile, Nicola Silvestris, Emanuele Felli, Francesco Giuseppe Foschi, Giorgio Ercolani, Giorgia Marisi, Martina Valgiusti, Alessandro Passardi, Marco Puzzoni, Marianna Silletta, Oronzo Brunetti, Giovanni Gerardo Cardellino, Giovanni Luca Frassineti,  and Mario Scartozzi
66699-66708
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Progress and future prospect of in vitro spermatogenesis

Progress and future prospect of in vitro spermatogenesis

https://doi.org/10.18632/oncotarget.19640

Fahar Ibtisham, Jiang Wu, Mei Xiao, Lilong An, Zachary Banker, Aamir Nawab, Yi Zhao,  and GuangHui Li
66709-66727
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B lymphoblastic leukemia/lymphoma: new insights into genetics, molecular aberrations, subclassification and targeted therapy

B lymphoblastic leukemia/lymphoma: new insights into genetics, molecular aberrations, subclassification and targeted therapy

https://doi.org/10.18632/oncotarget.19271

Xiaohui Zhang, Prerna Rastogi, Bijal Shah,  and Ling Zhang
66728-66741
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Meeting Reports

Intratumoral heterogeneity and clonal evolution in blood malignancies and solid tumors

Intratumoral heterogeneity and clonal evolution in blood malignancies and solid tumors

https://doi.org/10.18632/oncotarget.20279

Ignacio Varela, Pablo Menendez,  and Alejandra Sanjuan-Pla
66742-66746
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