Oncotarget

Vol 8, No 32

August 8, 2017

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About The Cover

The cover for issue 32 of Oncotarget features Figure 7E, "A graphic model describing assay development, drug discovery and mechanistic studies with statins," from Villarino, et al.

Table of Contents

Editorial

Targeting TRIB3 and PML-RARα interaction against APL

Targeting TRIB3 and PML-RARα interaction against APL

https://doi.org/10.18632/oncotarget.19442

Ke Li, Feng Wang,  and Zhuo-Wei Hu
52012-52013
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Indole microbial metabolites: expanding and translating target(s)

Indole microbial metabolites: expanding and translating target(s)

https://doi.org/10.18632/oncotarget.19443

Sridhar Mani
52014-52015
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Priority Research Papers

Experimental African trypanosome infection suppresses the development of multiple myeloma in mice by inducing intrinsic apoptosis of malignant plasma cells

Experimental African trypanosome infection suppresses the development of multiple myeloma in mice by inducing intrinsic apoptosis of malignant plasma cells

https://doi.org/10.18632/oncotarget.18152

Nathan De Beule, Eline Menu, Mathieu J.M. Bertrand, Mérédis Favreau, Elke De Bruyne, Ken Maes, Kim De Veirman, Magdalena Radwanska, Afshin Samali, Stefan Magez, Karin Vanderkerken,  and Carl De Trez
52016-52025
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Characterization of midostaurin as a dual inhibitor of FLT3 and SYK and potentiation of FLT3 inhibition against FLT3-ITD-driven leukemia harboring activated SYK kinase

Characterization of midostaurin as a dual inhibitor of FLT3 and SYK and potentiation of FLT3 inhibition against FLT3-ITD-driven leukemia harboring activated SYK kinase

https://doi.org/10.18632/oncotarget.19036

Ellen L. Weisberg, Alexandre Puissant, Richard Stone, Martin Sattler, Sara J. Buhrlage, Jing Yang, Paul W. Manley, Chengcheng Meng, Michael Buonopane, John F. Daley, Suzan Lazo, Renee Wright, David M. Weinstock, Amanda L. Christie, Kimberly Stegmaier,  and James D. Griffin
52026-52044
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Tumor antigen CA125 suppresses antibody-dependent cellular cytotoxicity (ADCC) via direct antibody binding and suppressed Fc-γ receptor engagement

Tumor antigen CA125 suppresses antibody-dependent cellular cytotoxicity (ADCC) via direct antibody binding and suppressed Fc-γ receptor engagement

https://doi.org/10.18632/oncotarget.19090

James Bradford Kline, Rina P. Kennedy, Earl Albone, Qimin Chao, Shawn Fernando, Jennifer M. McDonough, Katherine Rybinski, Wenquan Wang, Elizabeth B. Somers, Charles Schweizer, Luigi Grasso,  and Nicholas C. Nicolaides
52045-52060
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Therapeutic vaccine to cure large mouse hepatocellular carcinomas

Therapeutic vaccine to cure large mouse hepatocellular carcinomas

https://doi.org/10.18632/oncotarget.19367

Zhen Han, De Yang, Anna Trivett,  and Joost J. Oppenheim
52061-52071
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Research Papers: Immunology

The “4 plus 2” rituximab protocol makes maintenance treatment unneeded in patients with refractory ANCA-associated vasculitis: A 10 years observation study

The “4 plus 2” rituximab protocol makes maintenance treatment unneeded in patients with refractory ANCA-associated vasculitis: A 10 years observation study

https://doi.org/10.18632/oncotarget.18120

Dario Roccatello, Savino Sciascia, Daniela Rossi, Mirella Alpa, Carla Naretto, Massimo Radin, Roberta Fenoglio, Simone Baldovino,  and Elisa Menegatti
52072-52077
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Research Papers: Autophagy and Cell Death

Activation of the Nrf2/ARE signaling pathway by probucol contributes to inhibiting inflammation and neuronal apoptosis after spinal cord injury

Activation of the Nrf2/ARE signaling pathway by probucol contributes to inhibiting inflammation and neuronal apoptosis after spinal cord injury

https://doi.org/10.18632/oncotarget.19107

Zipeng Zhou, Chang Liu, Shurui Chen, Haosen Zhao, Kang Zhou, Wei Wang, Yajiang Yuan, Zhuo Li, Yue Guo, Zhaoliang Shen,  and Xifan Mei
52078-52093
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Research Papers

Prognostic value of a systemic inflammatory response index in metastatic renal cell carcinoma and construction of a predictive model

Prognostic value of a systemic inflammatory response index in metastatic renal cell carcinoma and construction of a predictive model

https://doi.org/10.18632/oncotarget.10626

Liangyou Gu, Xin Ma, Lei Wang, Hongzhao Li, Luyao Chen, Xintao Li, Yu Zhang, Yongpeng Xie,  and Xu Zhang
52094-52103
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5-aza-2’-deoxycytidine (DAC) treatment downregulates the HPV E6 and E7 oncogene expression and blocks neoplastic growth of HPV-associated cancer cells

5-aza-2’-deoxycytidine (DAC) treatment downregulates the HPV E6 and E7 oncogene expression and blocks neoplastic growth of HPV-associated cancer cells

https://doi.org/10.18632/oncotarget.10631

Maximilian Stich, Lennard Ganss, Jens Puschhof, Elena-Sophie Prigge, Miriam Reuschenbach, Ana Guiterrez, Svetlana Vinokurova,  and Magnus von Knebel Doeberitz
52104-52117
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Quercetin inhibits Cr(VI)-induced malignant cell transformation by targeting miR-21-PDCD4 signaling pathway

Quercetin inhibits Cr(VI)-induced malignant cell transformation by targeting miR-21-PDCD4 signaling pathway

https://doi.org/10.18632/oncotarget.10130

Poyil Pratheeshkumar, Young-Ok Son, Sasidharan Padmaja Divya, Lei Wang, Lilia Turcios, Ram Vinod Roy, John Andrew Hitron, Donghern Kim, Jin Dai, Padmaja Asha, Zhuo Zhang,  and Xianglin Shi
52118-52131
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Combined CT-guided radiofrequency ablation with systemic chemotherapy improves the survival for nasopharyngeal carcinoma with oligometastasis in liver: Propensity score matching analysis

Combined CT-guided radiofrequency ablation with systemic chemotherapy improves the survival for nasopharyngeal carcinoma with oligometastasis in liver: Propensity score matching analysis

https://doi.org/10.18632/oncotarget.10383

Wang Li, Yutong Bai, Ming Wu, Lujun Shen, Feng Shi, Xuqi Sun, Caijin Lin, Boyang Chang, Changchuan Pan, Zhiwen Li,  and Peihong Wu
52132-52141
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Analysis of ESR1 and PIK3CA mutations in plasma cell-free DNA from ER-positive breast cancer patients

Analysis of ESR1 and PIK3CA mutations in plasma cell-free DNA from ER-positive breast cancer patients

https://doi.org/10.18632/oncotarget.18479

Takashi Takeshita, Yutaka Yamamoto, Mutsuko Yamamoto-Ibusuki, Mai Tomiguchi, Aiko Sueta, Keiichi Murakami, Yoko Omoto,  and Hirotaka Iwase
52142-52155
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Lower Beclin 1 downregulates HER2 expression to enhance tamoxifen sensitivity and predicts a favorable outcome for ER positive breast cancer

Lower Beclin 1 downregulates HER2 expression to enhance tamoxifen sensitivity and predicts a favorable outcome for ER positive breast cancer

https://doi.org/10.18632/oncotarget.11044

Yu Gu, Tianxiang Chen, Guangliang Li, Cong Xu, Zhenzhen Xu, Jing Zhang, Kuifeng He, Linyan Zheng, Zhonghai Guan, Xinyun Su, Jiang Cao,  and Lisong Teng
52156-52177
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Hepatic NK cell-mediated hypersensitivity to ConA-induced liver injury in mouse liver expressing hepatitis C virus polyprotein

Hepatic NK cell-mediated hypersensitivity to ConA-induced liver injury in mouse liver expressing hepatitis C virus polyprotein

https://doi.org/10.18632/oncotarget.11052

Qiuxia Fu, Shaoduo Yan, Licui Wang, Xiangguo Duan, Lei Wang, Yue Wang, Tao Wu, Xiaohui Wang, Jie An, Yulong Zhang, Qianqian Zhou,  and Linsheng Zhan
52178-52192
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Association of high microvessel αvβ3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126

Association of high microvessel αvβ3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126

https://doi.org/10.18632/oncotarget.13386

Anat Erdreich-Epstein, Alok R. Singh, Shweta Joshi, Francisco M. Vega, Pinzheng Guo, Jingying Xu, Susan Groshen, Wei Ye, Melissa Millard, Mihaela Campan, Guillermo Morales, Joseph R. Garlich, Peter W. Laird, Robert C. Seeger, Hiroyuki Shimada,  and Donald L. Durden
52193-52210
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The pseudogene derived long noncoding RNA DUXAP8 promotes gastric cancer cell proliferation and migration via epigenetically silencing PLEKHO1 expression

The pseudogene derived long noncoding RNA DUXAP8 promotes gastric cancer cell proliferation and migration via epigenetically silencing PLEKHO1 expression

https://doi.org/10.18632/oncotarget.11075

Hong-Wei Ma, Min Xie, Ming Sun, Tian-Yu Chen, Rong-Rong Jin, Tian-Shi Ma, Qin-Nan Chen, Er-Bao Zhang, Xue-Zhi He, Wei De,  and Zhi-Hong Zhang
52211-52224
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nurse-like cells promote CLL survival through LFA-3/CD2 interactions

Nurse-like cells promote CLL survival through LFA-3/CD2 interactions

https://doi.org/10.18632/oncotarget.13660

Frédéric Boissard, Marie Tosolini, Laetitia Ligat, Anne Quillet-Mary, Frederic Lopez, Jean-Jacques Fournié, Loic Ysebaert,  and Mary Poupot
52225-52236
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Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer

Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer

https://doi.org/10.18632/oncotarget.11111

Carolina Soekmadji, James D. Riches, Pamela J. Russell, Jayde E. Ruelcke, Stephen McPherson, Chenwei Wang, Chris M. Hovens, Niall M. Corcoran, The Australian Prostate Cancer Collaboration BioResource, Michelle M. Hill,  and Colleen C. Nelson
52237-52255
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Adult T cell leukemia aggressivenness correlates with loss of both 5-hydroxymethylcytosine and TET2 expression

Adult T cell leukemia aggressivenness correlates with loss of both 5-hydroxymethylcytosine and TET2 expression

https://doi.org/10.18632/oncotarget.13665

Ambroise Marçais, Laetitia Waast, Julie Bruneau, Katia Hanssens, Vahid Asnafi, Philippe Gaulard, Felipe Suarez, Patrice Dubreuil, Antoine Gessain, Olivier Hermine,  and Claudine Pique
52256-52268
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The mTOR inhibitor everolimus in combination with azacitidine in patients with relapsed/refractory acute myeloid leukemia: a phase Ib/II study

The mTOR inhibitor everolimus in combination with azacitidine in patients with relapsed/refractory acute myeloid leukemia: a phase Ib/II study

https://doi.org/10.18632/oncotarget.13699

Peter Tan, Ing Soo Tiong, Shaun Fleming, Giovanna Pomilio, Nik Cummings, Mark Droogleever, Julie McManus, Anthony Schwarer, John Catalano, Sushrut Patil, Sharon Avery, Andrew Spencer,  and Andrew Wei
52269-52280
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The type I insulin-like growth factor regulates the liver stromal response to metastatic colon carcinoma cells

The type I insulin-like growth factor regulates the liver stromal response to metastatic colon carcinoma cells

https://doi.org/10.18632/oncotarget.12595

Maria Celia Fernandez, Roni Rayes, Boram Ham, Ni Wang, France Bourdeau, Simon Milette, Martin lllemann, Nigel Bird, Ali Majeed, Jun Xu, Tatiana Kisselova,  and Pnina Brodt
52281-52293
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Suppression of microRNA-205-5p in human mesenchymal stem cells improves their therapeutic potential in treating diabetic foot disease

Suppression of microRNA-205-5p in human mesenchymal stem cells improves their therapeutic potential in treating diabetic foot disease

https://doi.org/10.18632/oncotarget.17012

Lingyan Zhu, Gongxian Wang, Shane Fischbach,  and Xiangwei Xiao
52294-52303
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Detection of BRAF, NRAS, KIT, GNAQ, GNA11 and MAP2K1/2 mutations in Russian melanoma patients using LNA PCR clamp and biochip analysis

Detection of BRAF, NRAS, KIT, GNAQ, GNA11 and MAP2K1/2 mutations in Russian melanoma patients using LNA PCR clamp and biochip analysis

https://doi.org/10.18632/oncotarget.17014

Marina Emelyanova, Lilit Ghukasyan, Ivan Abramov, Oxana Ryabaya, Evgenia Stepanova, Anna Kudryavtseva, Asiya Sadritdinova, Cholpon Dzhumakova, Tatiana Belysheva, Sergey Surzhikov, Lyudmila Lyubchenko, Alexander Zasedatelev,  and Tatiana Nasedkina
52304-52320
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oncogenic secretory clusterin in hepatocellular carcinoma: Expression at early staging and emerging molecular target

Oncogenic secretory clusterin in hepatocellular carcinoma: Expression at early staging and emerging molecular target

https://doi.org/10.18632/oncotarget.13674

Wenjie Zheng, Min Yao, Qi Qian, Wenli Sai, Liwei Qiu, Junling Yang, Wei Wu, Zhizhen Dong,  and Dengfu Yao
52321-52332
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Positive regulation of TAZ expression by EBV-LMP1 contributes to cell proliferation and epithelial-mesenchymal transition in nasopharyngeal carcinoma

Positive regulation of TAZ expression by EBV-LMP1 contributes to cell proliferation and epithelial-mesenchymal transition in nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.13775

Jiang He, Feiyu Tang, Liyu Liu, Lin Chen, Jiang Li, Danming Ou, Lu Zhang, Zhi Li, Deyun Feng, Wenzheng Li,  and Lun-Quan Sun
52333-52344
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting aldehyde dehydrogenase activity in head and neck squamous cell carcinoma with a novel small molecule inhibitor

Targeting aldehyde dehydrogenase activity in head and neck squamous cell carcinoma with a novel small molecule inhibitor

https://doi.org/10.18632/oncotarget.17017

Jeewon Kim, June Ho Shin, Che-Hong Chen, Leslie Cruz, Lovisa Farnebo, Jieying Yang, Paula Borges, Gugene Kang, Daria Mochly-Rosen,  and John B. Sunwoo
52345-52356
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic and clinicopathologic significance of SIRT1 expression in hepatocellular carcinoma

Prognostic and clinicopathologic significance of SIRT1 expression in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.14096

Hongyuan Jiang, Xiao Zhang, Yuquan Tao, Liang Shan, Qijun Jiang, Yongchun Yu, Feng Cai,  and Lifang Ma
52357-52365
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comparisons of short-term and survival outcomes of laparoscopy-assisted versus open total gastrectomy for gastric cancer patients

Comparisons of short-term and survival outcomes of laparoscopy-assisted versus open total gastrectomy for gastric cancer patients

https://doi.org/10.18632/oncotarget.17019

Xin-Zu Chen, Shao-Yong Wang, Yin-Su Wang, Zi-Han Jiang, Wei-Han Zhang, Kai Liu, Kun Yang, Xiao-Long Chen, Lin-Yong Zhao, Meng Qiu, Hong-Feng Gou, Zong-Guang Zhou,  and Jian-Kun Hu
52366-52380
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Galeterone and its analogs inhibit Mnk-eIF4E axis, synergize with gemcitabine, impede pancreatic cancer cell migration, invasion and proliferation and inhibit tumor growth in mice

Galeterone and its analogs inhibit Mnk-eIF4E axis, synergize with gemcitabine, impede pancreatic cancer cell migration, invasion and proliferation and inhibit tumor growth in mice

https://doi.org/10.18632/oncotarget.14154

Andrew K. Kwegyir-Afful, Francis N. Murigi, Puranik Purushottamachar, Vidya P. Ramamurthy, Marlena S. Martin,  and Vincent C.O. Njar
52381-52402
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Expression analysis of microRNA as prognostic biomarkers in colorectal cancer

Expression analysis of microRNA as prognostic biomarkers in colorectal cancer

https://doi.org/10.18632/oncotarget.14175

Jie Yang, Dongling Ma, Andrew Fesler, Haiyan Zhai, Apisri Leamniramit, Wenzhe Li, Song Wu,  and Jingfang Ju
52403-52412
Abstract  |  PDF  |  HTML  |  Order a Reprint

A phase I trial of azacitidine and nanoparticle albumin bound paclitaxel in patients with advanced or metastatic solid tumors

A phase I trial of azacitidine and nanoparticle albumin bound paclitaxel in patients with advanced or metastatic solid tumors

https://doi.org/10.18632/oncotarget.14183

Adam L. Cohen, Abhijit Ray, Matthew Van Brocklin, David M. Burnett, Randy C. Bowen, Donna L. Dyess, Thomas W. Butler, Theresa Dumlao,  and Hung T. Khong
52413-52419
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Unit resection of buccal squamous cell carcinoma: Description of a new surgical technique

Unit resection of buccal squamous cell carcinoma: Description of a new surgical technique

https://doi.org/10.18632/oncotarget.14191

Zhen-Hu Ren, Zhao-Jian Gong,  and Han-Jiang Wu
52420-52431
Abstract  |  PDF  |  HTML  |  Order a Reprint

CRABP-II enhances pancreatic cancer cell migration and invasion by stabilizing interleukin 8 expression

CRABP-II enhances pancreatic cancer cell migration and invasion by stabilizing interleukin 8 expression

https://doi.org/10.18632/oncotarget.14194

Shuiliang Yu, Neetha Parameswaran, Ming Li, Yiwei Wang, Mark W. Jackson, Huiping Liu, Wei Xin,  and Lan Zhou
52432-52444
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Eribulin alone or in combination with the PLK1 inhibitor BI 6727 triggers intrinsic apoptosis in Ewing sarcoma cell lines

Eribulin alone or in combination with the PLK1 inhibitor BI 6727 triggers intrinsic apoptosis in Ewing sarcoma cell lines

https://doi.org/10.18632/oncotarget.17190

Lilly Magdalena Weiß, Manuela Hugle,  and Simone Fulda
52445-52456
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic role of podocalyxin-like protein expression in various cancers: A systematic review and meta-analysis

Prognostic role of podocalyxin-like protein expression in various cancers: A systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.14199

Jing Wang, Yongzhao Zhao, Ruizhao Qi, Xiaoning Zhu, Chenshen Huang, Sijin Cheng, Shengzhi Wang,  and Xiaolong Qi
52457-52464
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-199a-3p suppresses proliferation and invasion of prostate cancer cells by targeting Smad1

MiR-199a-3p suppresses proliferation and invasion of prostate cancer cells by targeting Smad1

https://doi.org/10.18632/oncotarget.17191

Feng Qu, Jinyu Zheng, Weidong Gan, Huibo Lian, Hua He, Wuping Li, Tian Yuan, Yaling Yang, Xiaogong Li, Changwei Ji, Xiang Yan, Linfeng Xu,  and Hongqian Guo
52465-52473
Abstract  |  PDF  |  HTML  |  Order a Reprint

Whole tumor RNA-sequencing and deconvolution reveal a clinically-prognostic PTEN/PI3K-regulated glioma transcriptional signature

Whole tumor RNA-sequencing and deconvolution reveal a clinically-prognostic PTEN/PI3K-regulated glioma transcriptional signature

https://doi.org/10.18632/oncotarget.17193

Yuan Pan, Erin C. Bush, Joseph A. Toonen, Yu Ma, Anne C. Solga, Peter A. Sims,  and David H. Gutmann
52474-52487
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prostate-derived ETS factor improves prognosis and represses proliferation and invasion in hepatocellular carcinoma

Prostate-derived ETS factor improves prognosis and represses proliferation and invasion in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.14924

Er-Bao Chen, Shao-Lai Zhou, Xu-Guang Pang, Dan Yin, Pei-Zhen Miao, Yi Yang, Qing Chen, Kai Zhu, Dong-Mei Gao, Tian-Shu Liu, Xiao-Yi Wang, Ying-Hong Shi, Wei-Zhong Wu, Jian Zhou, Zheng-Jun Zhou,  and Zhi Dai
52488-52500
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Excessive matrix metalloprotease-mediated degradation of interstitial tissue (type I collagen) independently predicts short-term survival in an observational study of postmenopausal women diagnosed with cancer

Excessive matrix metalloprotease-mediated degradation of interstitial tissue (type I collagen) independently predicts short-term survival in an observational study of postmenopausal women diagnosed with cancer

https://doi.org/10.18632/oncotarget.15275

Nicholas Willumsen, Cecilie L. Bager, Stephanie N. Kehlet, Katrine Dragsbaek, Jesper S. Neergaard, Henrik B. Hansen, Anne-Christine Bay-Jensen, Diana J. Leeming, Allan Lipton, Claus Christiansen,  and Morten Karsdal
52501-52510
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Api5 a new cofactor of estrogen receptor alpha involved in breast cancer outcome

Api5 a new cofactor of estrogen receptor alpha involved in breast cancer outcome

https://doi.org/10.18632/oncotarget.17281

Céline Basset, Florence Bonnet-Magnaval, Marina Garcia-Jove Navarro, Christian Touriol, Monique Courtade, Hervé Prats, Barbara Garmy-Susini,  and Eric Lacazette
52511-52526
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Effects of microRNA-126 on cell proliferation, apoptosis and tumor angiogenesis via the down-regulating ERK signaling pathway by targeting EGFL7 in hepatocellular carcinoma

Effects of microRNA-126 on cell proliferation, apoptosis and tumor angiogenesis via the down-regulating ERK signaling pathway by targeting EGFL7 in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.17283

Cheng Gong, Jing Fang, Guang Li, Han-Han Liu,  and Zhi-Su Liu
52527-52542
Abstract  |  PDF  |  HTML  |  Order a Reprint

New in vivo avatars of diffuse intrinsic pontine gliomas (DIPG) from stereotactic biopsies performed at diagnosis

New in vivo avatars of diffuse intrinsic pontine gliomas (DIPG) from stereotactic biopsies performed at diagnosis

https://doi.org/10.18632/oncotarget.15002

Alexandre Plessier, Ludivine LeDret, Pascale Varlet, Kevin Beccaria, Joelle Lacombe, Sebastien Meriaux, Francoise Geffroy, Laurence Fiette, Patricia Flamant, Fabrice Chretien, Thomas Blauwblomme, Stephanie Puget, Jacques Grill, Marie-Anne Debily,  and David Castel
52543-52559
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hepatitis B virus surface proteins accelerate cholestatic injury and tumor progression in Abcb4-knockout mice

Hepatitis B virus surface proteins accelerate cholestatic injury and tumor progression in Abcb4-knockout mice

https://doi.org/10.18632/oncotarget.15003

Daniel Zahner, Hannah Glimm, Tomomitsu Matono, Yuri Churin, Diran Herebian, Ertan Mayatepek, Kernt Köhler, Stefan Gattenlöhner, Anne Stinn, Annette Tschuschner, Martin Roderfeld,  and Elke Roeb
52560-52570
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Integrated expression profiles analysis reveals novel predictive biomarker in pancreatic ductal adenocarcinoma

Integrated expression profiles analysis reveals novel predictive biomarker in pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.16732

Hongzhe Li, Xinjing Wang, Yuan Fang, Zhen Huo, Xiongxiong Lu, Xi Zhan, Xiaxin Deng, Chenghong Peng,  and Baiyong Shen
52571-52583
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

siRNA-mediated inactivation of HER3 improves the antitumour activity and sensitivity of gefitinib in gastric cancer cells

siRNA-mediated inactivation of HER3 improves the antitumour activity and sensitivity of gefitinib in gastric cancer cells

https://doi.org/10.18632/oncotarget.17526

Heng-Heng Yuan, Ying-Nan Yang, Jian-Hua Zhou, Yan-Jing Li, Li-Ying Wang, Jun-Wei Qin, Tao Liu, Zhen-Zhen Li, Qing-Xin Zhou, Xiao-Li Wei, Ting-Ting Zhang, Peng Huang, Wen-Jie Zhang, Lei Liu, Xiao-Xue Du,  and Yu Han
52584-52593
Abstract  |  PDF  |  HTML  |  Order a Reprint

Intercellular adhesion molecule 1 rs5498 polymorphism is associated with the risk of myocardial infarction

Intercellular adhesion molecule 1 rs5498 polymorphism is associated with the risk of myocardial infarction

https://doi.org/10.18632/oncotarget.17529

Pengfei Hu, Tao Dai, Weiwei Yu, Ying Luo,  and Shuwei Huang
52594-52603
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of long non-coding RNAs biomarkers associated with progression of endometrial carcinoma and patient outcomes

Identification of long non-coding RNAs biomarkers associated with progression of endometrial carcinoma and patient outcomes

https://doi.org/10.18632/oncotarget.17537

Yanan Sun, Xiaoyan Zou, Jun He,  and Yuqin Mao
52604-52613
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MM-BMSCs induce naïve CD4+ T lymphocytes dysfunction through fibroblast activation protein α

MM-BMSCs induce naïve CD4+ T lymphocytes dysfunction through fibroblast activation protein α

https://doi.org/10.18632/oncotarget.17538

Xiaofei Wu, Yadan Wang, Jian Xu, Ting Luo, Jun Deng,  and Yu Hu
52614-52628
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Antagonistic effects of selenium on cadmium-induced apoptosis by restoring the mitochondrial dynamic equilibrium and energy metabolism in chicken spleens

Antagonistic effects of selenium on cadmium-induced apoptosis by restoring the mitochondrial dynamic equilibrium and energy metabolism in chicken spleens

https://doi.org/10.18632/oncotarget.17539

Zhe Xu, Xi Jin, Tingru Pan, Tianqi Liu, Na Wan,  and Shu Li
52629-52641
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Suppression of pyruvate dehydrogenase kinase-2 re-sensitizes paclitaxel-resistant human lung cancer cells to paclitaxel

Suppression of pyruvate dehydrogenase kinase-2 re-sensitizes paclitaxel-resistant human lung cancer cells to paclitaxel

https://doi.org/10.18632/oncotarget.16991

Hong Sun, Anyou Zhu, Xiang Zhou,  and Fengchao Wang
52642-52650
Abstract  |  PDF  |  HTML  |  Order a Reprint

Combination treatment with transarterial chemoembolization, radiotherapy, and hyperthermia (CERT) for hepatocellular carcinoma with portal vein tumor thrombosis: Final results of a prospective phase II trial

Combination treatment with transarterial chemoembolization, radiotherapy, and hyperthermia (CERT) for hepatocellular carcinoma with portal vein tumor thrombosis: Final results of a prospective phase II trial

https://doi.org/10.18632/oncotarget.17072

Jeong Il Yu, Hee Chul Park, Sang Hoon Jung, Changhoon Choi, Sung Wook Shin, Sung Ki Cho, Dong Hyun Sinn, Yong-Han Paik, Geum-Youn Gwak, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Byung Chul Yoo, Hüseyin Sahinbas,  and Seung Woon Paik
52651-52664
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value of Flotillin-1 expression in patients with solid tumors

Prognostic value of Flotillin-1 expression in patients with solid tumors

https://doi.org/10.18632/oncotarget.17075

Yang-Xi Ou, Fang-Teng Liu, Fang-Ying Chen,  and Zheng-Ming Zhu
52665-52677
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Transcription factor c-Rel is indispensable for generation of thymic but not of peripheral Foxp3+ regulatory T cells

Transcription factor c-Rel is indispensable for generation of thymic but not of peripheral Foxp3+ regulatory T cells

https://doi.org/10.18632/oncotarget.17079

Maik Luu, Elena Jenike, Niyati Vachharajani,  and Alexander Visekruna
52678-52689
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Erectile dysfunction and the risk of prostate cancer

Erectile dysfunction and the risk of prostate cancer

https://doi.org/10.18632/oncotarget.17082

Wei-Yu Lin, Ying-Hsu Chang, Cheng-Li Lin, Chia-Hung Kao,  and Hsi-Chin Wu
52690-52698
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TBX2 over-expression promotes nasopharyngeal cancer cell proliferation and invasion

TBX2 over-expression promotes nasopharyngeal cancer cell proliferation and invasion

https://doi.org/10.18632/oncotarget.17084

Yan Lv, Meng Si, Nannan Chen, Ya Li, Xingkai Ma, Huijun Yang, Ling Zhang, Hongyan Zhu, Guang-yin Xu, Ge-ping Wu,  and C. Cao
52699-52707
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Detection of nasopharyngeal carcinoma susceptibility with single nucleotide polymorphism analysis using next-generation sequencing technology

Detection of nasopharyngeal carcinoma susceptibility with single nucleotide polymorphism analysis using next-generation sequencing technology

https://doi.org/10.18632/oncotarget.17085

Mu-Yun Wu, Shu-Jing Huang, Fan Yang, Xin-Tian Qin, Ying Ding, Shu Yang,  and Xi-Cheng Wang
52708-52723
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mitral isthmus ablation using a circular mapping catheter positioned in the left atrial appendage as a reference for conduction block

Mitral isthmus ablation using a circular mapping catheter positioned in the left atrial appendage as a reference for conduction block

https://doi.org/10.18632/oncotarget.17092

Takahiko Nishiyama, Takehiro Kimura, Taishi Fujisawa, Kazuaki Nakajima, Akira Kunitomi, Shin Kashimura, Yoshinori Katsumata, Nobuhiro Nishiyama, Yoshiyasu Aizawa, Keiichi Fukuda,  and Seiji Takatsuki
52724-52734
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NFATc3 mediates the sensitivity of gastric cancer cells to arsenic sulfide

NFATc3 mediates the sensitivity of gastric cancer cells to arsenic sulfide

https://doi.org/10.18632/oncotarget.17175

Xiuli Zhang, Ting Kang, Lian Zhang, Yingying Tong, Wenping Ding,  and Siyu Chen
52735-52745
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Transgenic overexpression of NanogP8 in the mouse prostate is insufficient to initiate tumorigenesis but weakly promotes tumor development in the Hi-Myc mouse model

Transgenic overexpression of NanogP8 in the mouse prostate is insufficient to initiate tumorigenesis but weakly promotes tumor development in the Hi-Myc mouse model

https://doi.org/10.18632/oncotarget.17186

Bigang Liu, Shuai Gong, Qiuhui Li, Xin Chen, John Moore, Mahipal V. Suraneni, Mark D. Badeaux, Collene R. Jeter, Jianjun Shen, Rashid Mehmood, Qingxia Fan,  and Dean G. Tang
52746-52760
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Downregulated long noncoding RNA ALDBGALG0000005049 induces inflammation in chicken muscle suffered from selenium deficiency by regulating stearoyl-CoA desaturase

Downregulated long noncoding RNA ALDBGALG0000005049 induces inflammation in chicken muscle suffered from selenium deficiency by regulating stearoyl-CoA desaturase

https://doi.org/10.18632/oncotarget.17187

Ruifeng Fan, Changyu Cao, Xia Zhao, Qunxiang Shi, Jinxin Zhao,  and Shiwen Xu
52761-52774
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Middle-distance running acutely influences the concentration and composition of serum bile acids: Potential implications for cancer risk?

Middle-distance running acutely influences the concentration and composition of serum bile acids: Potential implications for cancer risk?

https://doi.org/10.18632/oncotarget.17188

Elisa Danese, Gian Luca Salvagno, Cantor Tarperi, Davide Negrini, Martina Montagnana, Luca Festa, Fabian Sanchis-Gomar, Federico Schena,  and Giuseppe Lippi
52775-52782
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Toxicarioside O induces protective autophagy in a sirtuin-1-dependent manner in colorectal cancer cells

Toxicarioside O induces protective autophagy in a sirtuin-1-dependent manner in colorectal cancer cells

https://doi.org/10.18632/oncotarget.17189

Yong-Hao Huang, Yan Sun, Feng-Ying Huang, Yue-Nan Li, Cai-Chun Wang, Wen-Li Mei, Hao-Fu Dai, Guang-Hong Tan,  and Canhua Huang
52783-52791
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prediction of EGFR and KRAS mutation in non-small cell lung cancer using quantitative 18F FDG-PET/CT metrics

Prediction of EGFR and KRAS mutation in non-small cell lung cancer using quantitative 18F FDG-PET/CT metrics

https://doi.org/10.18632/oncotarget.17782

Ryogo Minamimoto, Mehran Jamali, Olivier Gevaert, Sebastian Echegaray, Amanda Khuong, Chuong D. Hoang, Joseph B. Shrager, Sylvia K. Plevritis, Daniel L. Rubin, Ann N. Leung, Sandy Napel,  and Andrew Quon
52792-52801
Abstract  |  PDF  |  HTML  |  Order a Reprint

High-resolution dynamic imaging and quantitative analysis of lung cancer xenografts in nude mice using clinical PET/CT

High-resolution dynamic imaging and quantitative analysis of lung cancer xenografts in nude mice using clinical PET/CT

https://doi.org/10.18632/oncotarget.17263

Ying Yi Wang, Kai Wang, Zuo Yu Xu, Yan Song, Chu Nan Wang, Chong Qing Zhang, Xi Lin Sun,  and Bao Zhong Shen
52802-52812
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Apatinib inhibits VEGFR-2 and angiogenesis in an in vivo murine model of nasopharyngeal carcinoma

Apatinib inhibits VEGFR-2 and angiogenesis in an in vivo murine model of nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.17264

Qiu-Xia Peng, Yun-Wei Han, Yan-Ling Zhang, Jie Hu, Juan Fan, Shao-Zhi Fu, Shan Xu,  and Qiang Wan
52813-52822
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Chromatin remodeling modulates radiosensitivity of the daughter cells derived from cell population exposed to low- and high-LET irradiation

Chromatin remodeling modulates radiosensitivity of the daughter cells derived from cell population exposed to low- and high-LET irradiation

https://doi.org/10.18632/oncotarget.17275

Ping Wang, Dexiao Yuan, Fei Guo, Xiaoyan Chen, Lin Zhu, Hang Zhang, Chen Wang,  and Chunlin Shao
52823-52836
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Uridine diphosphate-glucuronosyltransferase 2B15 D85Y gene polymorphism is associated with lower prostate cancer risk: a systematic review and meta-analysis

Uridine diphosphate-glucuronosyltransferase 2B15 D85Y gene polymorphism is associated with lower prostate cancer risk: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.17375

Xiao Zhong, Jiayu Feng, Ya Xiao, Pingxian Wang, Qiming Fan, Ronghua Wu, Wengang Hu,  and Chibing Huang
52837-52845
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Changing trends in the prevalence of anencephaly in Liaoning province of Northeast China from 2006–2015: data from a population-based birth defects registry

Changing trends in the prevalence of anencephaly in Liaoning province of Northeast China from 2006–2015: data from a population-based birth defects registry

https://doi.org/10.18632/oncotarget.17423

Ting-Ting Gong, Qi-Jun Wu, Yan-Ling Chen, Cheng-Zhi Jiang, Da Li, Jing Li, Li-Li Li, Chen Zhou,  and Yan-Hong Huang
52846-52853
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OVA12 promotes tumor growth by regulating p53 expression in human cancer cells

OVA12 promotes tumor growth by regulating p53 expression in human cancer cells

https://doi.org/10.18632/oncotarget.17501

Renfeng Zhang, Xicai Wu, Xiangfeng Xia, Asma Khanniche, Feifei Song, Bingchang Zhang, Ying Wang,  and Hailiang Ge
52854-52865
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Treatment of hepatocellular carcinoma with a GPC3-targeted bispecific T cell engager

Treatment of hepatocellular carcinoma with a GPC3-targeted bispecific T cell engager

https://doi.org/10.18632/oncotarget.17905

Yanyu Bi, Hua Jiang, Peng Wang, Bo Song, Huamao Wang, Xianming Kong,  and Zonghai Li
52866-52876
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The anti-ErbB2 antibody H2-18 and the pan-PI3K inhibitor GDC-0941 effectively inhibit trastuzumab-resistant ErbB2-overexpressing breast cancer

The anti-ErbB2 antibody H2-18 and the pan-PI3K inhibitor GDC-0941 effectively inhibit trastuzumab-resistant ErbB2-overexpressing breast cancer

https://doi.org/10.18632/oncotarget.17907

Lingfei Wang, Xiaojie Yu, Chao Wang, Shujun Pan, Beibei Liang, Yajun Zhang, Xiaodan Chong, Yanchun Meng, Jian Dong, Yirong Zhao, Yang Yang, Huajing Wang, Jie Gao, Huafeng Wei, Jian Zhao, Hao Wang, Chaohua Hu, Wenze Xiao,  and Bohua Li
52877-52888
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PD-L1: a novel prognostic biomarker in head and neck squamous cell carcinoma

PD-L1: a novel prognostic biomarker in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.17547

Tim Müller, Martin Braun, Dimo Dietrich, Seher Aktekin, Simon Höft, Glen Kristiansen, Friederike Göke, Andreas Schröck, Johannes Brägelmann, Stefanie A.E. Held, Friedrich Bootz,  and Peter Brossart
52889-52900
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Twist1 confers multidrug resistance in colon cancer through upregulation of ATP-binding cassette transporters

Twist1 confers multidrug resistance in colon cancer through upregulation of ATP-binding cassette transporters

https://doi.org/10.18632/oncotarget.17548

Yan-Rong Liu, Lan Liang, Jian Min Zhao, Yang Zhang, Min Zhang, Wei-Long Zhong, Qiang Zhang, Jun-Jie Wei, Meng Li, Jie Yuan, Shuang Chen, Shu-Min Zong, Hui-Juan Liu, Jing Meng, Yuan Qin, Bo Sun, Lan Yang, Hong-Gang Zhou, Tao Sun,  and Cheng Yang
52901-52912
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-106b regulates the 5-fluorouracil resistance by targeting Zbtb7a in cholangiocarcinoma

miR-106b regulates the 5-fluorouracil resistance by targeting Zbtb7a in cholangiocarcinoma

https://doi.org/10.18632/oncotarget.17577

Dechao Jiao, Yan Yan, Shaofeng Shui, Gang Wu, JianZhuang Ren, Yanli Wang,  and Xinwei Han
52913-52922
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Effect and mechanism of inhibition of PI3K/Akt/mTOR signal pathway on chronic neuropathic pain and spinal microglia in a rat model of chronic constriction injury

Effect and mechanism of inhibition of PI3K/Akt/mTOR signal pathway on chronic neuropathic pain and spinal microglia in a rat model of chronic constriction injury

https://doi.org/10.18632/oncotarget.17629

Jian-Rong Guo, Huan Wang, Xiao-Ju Jin, Dong-Lin Jia, Xun Zhou,  and Qiang Tao
52923-52934
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Selective Inhibitors of Nuclear Export (SINE) compounds block proliferation and migration of triple negative breast cancer cells by restoring expression of ARRDC3

Selective Inhibitors of Nuclear Export (SINE) compounds block proliferation and migration of triple negative breast cancer cells by restoring expression of ARRDC3

https://doi.org/10.18632/oncotarget.17987

Young Hwa Soung, Trinayan Kashyap, Thalia Nguyen, Garima Yadav, Hua Chang, Yosef Landesman,  and Jun Chung
52935-52947
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-486-5p negatively regulates oncogenic NEK2 in hepatocellular carcinoma

MiR-486-5p negatively regulates oncogenic NEK2 in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.17635

Shun-Jun Fu, Jian Chen, Fei Ji, Wei-Qiang Ju, Qiang Zhao, Mao-Gen Chen, Zhi-Yong Guo, Lin-Wei Wu, Yi Ma, Dong-Ping Wang, Xiao-Feng Zhu,  and Xiao-Shun He
52948-52959
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TUSC3 induces autophagy in human non-small cell lung cancer cells through Wnt/β-catenin signaling

TUSC3 induces autophagy in human non-small cell lung cancer cells through Wnt/β-catenin signaling

https://doi.org/10.18632/oncotarget.17674

Yun Peng, Jun Cao, Xiao-Yi Yao, Jian-Xin Wang, Mei-Zuo Zhong, Ping-Ping Gan,  and Jian-Huang Li
52960-52974
Abstract  |  PDF  |  HTML  |  Order a Reprint

Mitochondrial DNA sequencing and large-scale genotyping identifies MT-ND4 gene mutation m.11696G>A associated with idiopathic oligoasthenospermia

Mitochondrial DNA sequencing and large-scale genotyping identifies MT-ND4 gene mutation m.11696G>A associated with idiopathic oligoasthenospermia

https://doi.org/10.18632/oncotarget.17675

Juan Ji, Miaofei Xu, Zhenyao Huang, Lei Li, Hongxiang Zheng, Shuping Yang, Shilin Li, Li Jin, Xiufeng Ling, Yankai Xia, Chuncheng Lu,  and Xinru Wang
52975-52982
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-133b down-regulates ABCC1 and enhances the sensitivity of CRC to anti-tumor drugs

miR-133b down-regulates ABCC1 and enhances the sensitivity of CRC to anti-tumor drugs

https://doi.org/10.18632/oncotarget.17677

Miao Chen, Daojiang Li, Ni Gong, Hao Wu, Chen Su, Canbin Xie, Hong Xiang, Changwei Lin,  and Xiaorong Li
52983-52994
Abstract  |  PDF  |  HTML  |  Order a Reprint

Pulmonary endothelial cell DNA methylation signature in pulmonary arterial hypertension

Pulmonary endothelial cell DNA methylation signature in pulmonary arterial hypertension

https://doi.org/10.18632/oncotarget.18031

Aurélie Hautefort, Julie Chesné, Jens Preussner, Soni S. Pullamsetti, Jorg Tost, Mario Looso, Fabrice Antigny, Barbara Girerd, Marianne Riou, Saadia Eddahibi, Jean-François Deleuze, Werner Seeger, Elie Fadel, Gerald Simonneau, David Montani, Marc Humbert,  and Frédéric Perros
52995-53016
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA profiles involved in trifluridine resistance

MicroRNA profiles involved in trifluridine resistance

https://doi.org/10.18632/oncotarget.18078

Kenta Tsunekuni, Masamitsu Konno, Ayumu Asai, Jun Koseki, Takashi Kobunai, Teiji Takechi, Yuichiro Doki, Masaki Mori,  and Hideshi Ishii
53017-53027
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dipeptidyl peptidase 4 inhibitor use is associated with a lower risk of incident acute kidney injury in patients with diabetes

Dipeptidyl peptidase 4 inhibitor use is associated with a lower risk of incident acute kidney injury in patients with diabetes

https://doi.org/10.18632/oncotarget.18081

Chia-Ter Chao, Jui Wang, Hon-Yen Wu, Kuo-Liong Chien,  and Kuan-Yu Hung
53028-53040
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long working hours, job satisfaction, and depressive symptoms: a community-based cross-sectional study among Japanese employees in small- and medium-scale businesses

Long working hours, job satisfaction, and depressive symptoms: a community-based cross-sectional study among Japanese employees in small- and medium-scale businesses

https://doi.org/10.18632/oncotarget.18084

Akinori Nakata
53041-53052
Abstract  |  PDF  |  HTML  |  Order a Reprint

Lenalidomide increases human dendritic cell maturation in multiple myeloma patients targeting monocyte differentiation and modulating mesenchymal stromal cell inhibitory properties

Lenalidomide increases human dendritic cell maturation in multiple myeloma patients targeting monocyte differentiation and modulating mesenchymal stromal cell inhibitory properties

https://doi.org/10.18632/oncotarget.18085

Federica Costa, Rosanna Vescovini, Marina Bolzoni, Valentina Marchica, Paola Storti, Denise Toscani, Fabrizio Accardi, Laura Notarfranchi, Benedetta Dalla Palma, Cristina Manferdini, Sabrina Manni, Giannalisa Todaro, Gina Lisignoli, Francesco Piazza, Franco Aversa,  and Nicola Giuliani
53053-53067
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN

Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN

https://doi.org/10.18632/oncotarget.18087

Andrea Cavazzoni, Silvia La Monica, Roberta Alfieri, Andrea Ravelli, Nele Van Der Steen, Rocco Sciarrillo, Denise Madeddu, Costanza Anna Maria Lagrasta, Federico Quaini, Mara Bonelli, Claudia Fumarola, Daniele Cretella, Graziana Digiacomo, Marcello Tiseo, Godefridus J. Peters, Andrea Ardizzoni, Pier Giorgio Petronini,  and Elisa Giovannetti
53068-53083
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RNase alleviates neurological dysfunction in mice undergoing cardiac arrest and cardiopulmonary resuscitation

RNase alleviates neurological dysfunction in mice undergoing cardiac arrest and cardiopulmonary resuscitation

https://doi.org/10.18632/oncotarget.18088

Ye Ma, Chan Chen, Shu Zhang, Qiao Wang, Hai Chen, Yuanlin Dong, Zheng Zhang, Yan Li, Zhendong Niu, Tao Zhu, Hai Yu,  and Bin Liu
53084-53099
Abstract  |  PDF  |  HTML  |  Order a Reprint

Discriminating patients with early-stage breast cancer from benign lesions by detection of oxidative DNA damage biomarker in urine

Discriminating patients with early-stage breast cancer from benign lesions by detection of oxidative DNA damage biomarker in urine

https://doi.org/10.18632/oncotarget.17831

Cheng Guo, Xiaofen Li, Minfeng Ye, Fei Xu, Jiekai Yu, Cong Xie, Xiaoji Cao, Mengzhe Guo, Ying Yuan,  and Shu Zheng
53100-53109
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Upregulation of long noncoding RNA HOXA-AS3 promotes tumor progression and predicts poor prognosis in glioma

Upregulation of long noncoding RNA HOXA-AS3 promotes tumor progression and predicts poor prognosis in glioma

https://doi.org/10.18632/oncotarget.18162

Fan Wu, Chuanbao Zhang, Jinquan Cai, Fan Yang, Tingyu Liang, Xiaoyan Yan, Haoyuan Wang, Wen Wang, Jing Chen,  and Tao Jiang
53110-53123
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Role of A-Kinase anchor protein (AKAP4) in growth and survival of ovarian cancer cells

Role of A-Kinase anchor protein (AKAP4) in growth and survival of ovarian cancer cells

https://doi.org/10.18632/oncotarget.18163

Vikash Kumar, Nirmala Jagadish,  and Anil Suri
53124-53136
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic values of tissue factor and its alternatively splice transcripts in human gastric cancer tissues

Prognostic values of tissue factor and its alternatively splice transcripts in human gastric cancer tissues

https://doi.org/10.18632/oncotarget.17942

Min Wu, Lujun Chen, Ting Xu, Bin Xu, Jingting Jiang,  and Changping Wu
53137-53145
Abstract  |  PDF  |  HTML  |  Order a Reprint

Menstrual pattern after abdominal radical trachelectomy

Menstrual pattern after abdominal radical trachelectomy

https://doi.org/10.18632/oncotarget.17943

Xiaoqi Li, Jin Li, Xingzhu Ju, Zhaoxia Jiang, Xiaojun Chen,  and Xiaohua Wu
53146-53153
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A screen for inducers of bHLH activity identifies pitavastatin as a regulator of p21, Rb phosphorylation and E2F target gene expression in pancreatic cancer

A screen for inducers of bHLH activity identifies pitavastatin as a regulator of p21, Rb phosphorylation and E2F target gene expression in pancreatic cancer

https://doi.org/10.18632/oncotarget.18587

Nicholas Villarino, Lia Signaevskaia, Jaco van Niekerk, Rachel Medal, Heejung Kim, Reyhaneh Lahmy, Kathleen Scully, Anthony Pinkerton, SangWun Kim, Andrew Lowy,  and Pamela Itkin-Ansari
53154-53167
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MEK inhibition enhances efficacy of bacillus Calmette-Guérin on bladder cancer cells by reducing release of Toll-like receptor 2-activated antimicrobial peptides

MEK inhibition enhances efficacy of bacillus Calmette-Guérin on bladder cancer cells by reducing release of Toll-like receptor 2-activated antimicrobial peptides

https://doi.org/10.18632/oncotarget.18230

Young Mi Whang, Su Bin Jin, Serk In Park,  and In Ho Chang
53168-53179
Abstract  |  PDF  |  HTML  |  Order a Reprint

Regulation of actin-binding protein ANLN by antitumor miR-217 inhibits cancer cell aggressiveness in pancreatic ductal adenocarcinoma

Regulation of actin-binding protein ANLN by antitumor miR-217 inhibits cancer cell aggressiveness in pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.18261

Tetsuya Idichi, Naohiko Seki, Hiroshi Kurahara, Keiichi Yonemori, Yusaku Osako, Takayuki Arai, Atsushi Okato, Yoshiaki Kita, Takaaki Arigami, Yuko Mataki, Yuko Kijima, Kosei Maemura,  and Shoji Natsugoe
53180-53193
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Altered erythropoiesis and decreased number of erythrocytes in children with neuroblastoma

Altered erythropoiesis and decreased number of erythrocytes in children with neuroblastoma

https://doi.org/10.18632/oncotarget.18285

Fabio Morandi, Sebastiano Barco, Sara Stigliani, Michela Croce, Luca Persico, Corrado Lagazio, Francesca Scuderi, Maria Luisa Belli, Mariapina Montera, Giuliana Cangemi, Sarah Pozzi, Valentina Rigo, Paola Scaruffi, Loredana Amoroso, Giovanni Erminio, Vito Pistoia, Silvano Ferrini,  and Maria Valeria Corrias
53194-53209
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Down regulation of human positive coactivator 4 suppress tumorigenesis and lung metastasis of osteosarcoma

Down regulation of human positive coactivator 4 suppress tumorigenesis and lung metastasis of osteosarcoma

https://doi.org/10.18632/oncotarget.18290

Xu Hu, Chao Zhang, Ying Zhang, Christopher S. Hong, Wugui Chen, Weiwei Shen, Hongkai Wang, Jianrong He, Pei Chen, Yue Zhou, Chunmeng Shi,  and Tongwei Chu
53210-53225
Abstract  |  PDF  |  HTML  |  Order a Reprint

Increased p16 and p53 protein expression predicts poor prognosis in mucosal melanoma

Increased p16 and p53 protein expression predicts poor prognosis in mucosal melanoma

https://doi.org/10.18632/oncotarget.18367

Hanbin Chen, Yangyang Li, Yin Long, Erjiang Tang, Rongrong Wang, Kate Huang, Congying Xie,  and Guorong Chen
53226-53233
Abstract  |  PDF  |  HTML  |  Order a Reprint

Associations of high altitude polycythemia with polymorphisms in EPHA2 and AGT in Chinese Han and Tibetan populations

Associations of high altitude polycythemia with polymorphisms in EPHA2 and AGT in Chinese Han and Tibetan populations

https://doi.org/10.18632/oncotarget.18384

Lijun Liu, Yao Zhang, Zhiying Zhang, Yiduo Zhao, Xiaowei Fan, Lifeng Ma, Yuan Zhang, Haijin He,  and Longli Kang
53234-53243
Abstract  |  PDF  |  HTML  |  Order a Reprint

CXCL13 is androgen-responsive and involved in androgen induced prostate cancer cell migration and invasion

CXCL13 is androgen-responsive and involved in androgen induced prostate cancer cell migration and invasion

https://doi.org/10.18632/oncotarget.18387

Long Fan, Qingyi Zhu, Li Liu, Cuicui Zhu, Haojie Huang, Shan Lu,  and Ping Liu
53244-53261
Abstract  |  PDF  |  HTML  |  Order a Reprint

Jagged-2 (JAG2) enhances tumorigenicity and chemoresistance of colorectal cancer cells

Jagged-2 (JAG2) enhances tumorigenicity and chemoresistance of colorectal cancer cells

https://doi.org/10.18632/oncotarget.18391

Vivek Vaish, Joohwee Kim,  and Minsub Shim
53262-53275
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Infiltrating macrophages in diabetic nephropathy promote podocytes apoptosis via TNF-α-ROS-p38MAPK pathway

Infiltrating macrophages in diabetic nephropathy promote podocytes apoptosis via TNF-α-ROS-p38MAPK pathway

https://doi.org/10.18632/oncotarget.18394

Yinfeng Guo, Zhixia Song, Min Zhou, Ying Yang, Yu Zhao, Bicheng Liu,  and Xiaoliang Zhang
53276-53287
Abstract  |  PDF  |  HTML  |  Order a Reprint

AKT can modulate the in vitro response of HNSCC cells to irreversible EGFR inhibitors

AKT can modulate the in vitro response of HNSCC cells to irreversible EGFR inhibitors

https://doi.org/10.18632/oncotarget.18395

Renato José Silva-Oliveira, Matias Melendez, Olga Martinho, Maicon F. Zanon, Luciano de Souza Viana, André Lopes Carvalho,  and Rui Manuel Reis
53288-53301
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A combination of valproic acid sodium salt, CHIR99021, E-616452, tranylcypromine, and 3-Deazaneplanocin A causes stem cell-like characteristics in cancer cells

A combination of valproic acid sodium salt, CHIR99021, E-616452, tranylcypromine, and 3-Deazaneplanocin A causes stem cell-like characteristics in cancer cells

https://doi.org/10.18632/oncotarget.18396

Shuang Sha, Yuanfen Zhai, Chengzhao Lin, Heyong Wang, Qing Chang, Shuang Song, Mingqiang Ren,  and Gentao Liu
53302-53312
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Differential metabonomic profiles of primary hepatocellular carcinoma tumors from alcoholic liver disease, HBV-infected, and HCV-infected cirrhotic patients

Differential metabonomic profiles of primary hepatocellular carcinoma tumors from alcoholic liver disease, HBV-infected, and HCV-infected cirrhotic patients

https://doi.org/10.18632/oncotarget.18397

Ding Cao, Can Cai, Mingxin Ye, Junhua Gong, Menghao Wang, Jinzheng Li,  and Jianping Gong
53313-53325
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Diagnostic and prognostic values of cerebrospinal fluid CYFRA 21-1 in patients with leptomeningeal carcinomatosis

Diagnostic and prognostic values of cerebrospinal fluid CYFRA 21-1 in patients with leptomeningeal carcinomatosis

https://doi.org/10.18632/oncotarget.18405

Jae-Won Hyun, Ji Hyun Park, Boo Gil Kang, Eun Young Park, Boram Park, Jungnam Joo, Jong Kuk Kim, Su-Hyun Kim, Jee Hyang Jeong, Hyang Woon Lee, Kee Duk Park, Kyung Gyu Choi, Sang-Hyun Hwang, Ho-Shin Gwak,  and Ho Jin Kim
53326-53335
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinicopathological characteristics of ROS1- and RET-rearranged NSCLC in caucasian patients: Data from a cohort of 713 non-squamous NSCLC lacking KRAS/EGFR/HER2/BRAF/PIK3CA/ALK alterations

Clinicopathological characteristics of ROS1- and RET-rearranged NSCLC in caucasian patients: Data from a cohort of 713 non-squamous NSCLC lacking KRAS/EGFR/HER2/BRAF/PIK3CA/ALK alterations

https://doi.org/10.18632/oncotarget.18408

Frédéric Dugay, Francisco Llamas-Gutierrez, Marjory Gournay, Sarah Medane, François Mazet, Dan Christian Chiforeanu, Emmanuelle Becker, Régine Lamy, Hervé Léna, Nathalie Rioux-Leclercq, Marc-Antoine Belaud-Rotureau,  and Florian Cabillic
53336-53351
Abstract  |  PDF  |  HTML  |  Order a Reprint

Autophagy-related genes are induced by histone deacetylase inhibitor suberoylanilide hydroxamic acid via the activation of cathepsin B in human breast cancer cells

Autophagy-related genes are induced by histone deacetylase inhibitor suberoylanilide hydroxamic acid via the activation of cathepsin B in human breast cancer cells

https://doi.org/10.18632/oncotarget.18410

Han Han, Jing Li, Xiuyan Feng, Hui Zhou, Shanchun Guo,  and Weiqiang Zhou
53352-53365
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dectin-1 signaling inhibits osteoclastogenesis via IL-33-induced inhibition of NFATc1

Dectin-1 signaling inhibits osteoclastogenesis via IL-33-induced inhibition of NFATc1

https://doi.org/10.18632/oncotarget.18411

Xiaoqing Zhu, Yinghua Zhao, Yuxue Jiang, Tianxue Qin, Jintong Chen, Xiao Chu, Qing Yi, Sujun Gao,  and Siqing Wang
53366-53374
Abstract  |  PDF  |  HTML  |  Order a Reprint

20(S)-Rg3 blocked epithelial-mesenchymal transition through DNMT3A/miR-145/FSCN1 in ovarian cancer

20(S)-Rg3 blocked epithelial-mesenchymal transition through DNMT3A/miR-145/FSCN1 in ovarian cancer

https://doi.org/10.18632/oncotarget.18482

Jie Li, Jiaojiao Lu, Zhongxue Ye, Xi Han, Xia Zheng, Huilian Hou, Wei Chen, Xu Li,  and Le Zhao
53375-53386
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

APIO-EE-9 is a novel Aurora A and B antagonist that suppresses esophageal cancer growth in a PDX mouse model

APIO-EE-9 is a novel Aurora A and B antagonist that suppresses esophageal cancer growth in a PDX mouse model

https://doi.org/10.18632/oncotarget.18508

Guoguo Jin, Ke Yao, Zhiping Guo, Zhenjiang Zhao, Kangdong Liu, Fangfang Liu, Hanyong Chen, Dhilli Rao Gorja, Kanamata Reddy, Ann M. Bode, Ziming Dong,  and Zigang Dong
53387-53404
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Brain metastases in patients with non-small cell lung cancer: the role of mutated-EGFRs with an exon 19 deletion or L858R point mutation in cancer cell dissemination

Brain metastases in patients with non-small cell lung cancer: the role of mutated-EGFRs with an exon 19 deletion or L858R point mutation in cancer cell dissemination

https://doi.org/10.18632/oncotarget.18509

Shih-Hsin Hsiao, Yu-Ting Chou, Sey-En Lin, Ru-Chun Hsu, Chi-Li Chung, Yu-Rung Kao, H. Eugene Liu,  and Cheng-Wen Wu
53405-53418
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Radial artery intima-media thickness regresses after secondary prevention interventions in patients’ post-acute coronary syndrome and is associated with cardiac and kidney biomarkers

Radial artery intima-media thickness regresses after secondary prevention interventions in patients’ post-acute coronary syndrome and is associated with cardiac and kidney biomarkers

https://doi.org/10.18632/oncotarget.18511

Damilola D. Adingupu, Helena U. Westergren, Santosh Dahgam, Ann-Cathrine Jönsson-Rylander, Juuso Blomster, Per Albertsson, Elmir Omerovic, Sara Svedlund,  and Li-Ming Gan
53419-53431
Abstract  |  PDF  |  HTML  |  Order a Reprint

An epigenetic signature of adhesion molecules predicts poor prognosis of ovarian cancer patients

An epigenetic signature of adhesion molecules predicts poor prognosis of ovarian cancer patients

https://doi.org/10.18632/oncotarget.18515

Ping-Ying Chang, Yu-Ping Liao, Hui-Chen Wang, Yu-Chih Chen, Rui-Lan Huang, Yu-Chi Wang, Chiou-Chung Yuan,  and Hung-Cheng Lai
53432-53449
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hypertriglyceridemia in female rats during pregnancy induces obesity in male offspring via altering hypothalamic leptin signaling

Hypertriglyceridemia in female rats during pregnancy induces obesity in male offspring via altering hypothalamic leptin signaling

https://doi.org/10.18632/oncotarget.18519

Tanzil Ur Rahman, Kamran Ullah, Zhang-Hong Ke, Meng-Xi Guo, Lu-Yang Jin, Jun Ren, Yu-Zhong Zhou, Yi Cheng, Xin-Yan Dong, Hai-Yan Pang, Ting-Ting Wang, Jian-Zhong Sheng,  and He-Feng Huang
53450-53464
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Differential gene and lncRNA expression in the lower thoracic spinal cord following ischemia/reperfusion-induced acute kidney injury in rats

Differential gene and lncRNA expression in the lower thoracic spinal cord following ischemia/reperfusion-induced acute kidney injury in rats

https://doi.org/10.18632/oncotarget.18584

Qing-Quan Liu, Hui Liu, Zhi-Gang He, Shi-Jie Zhang, Bao-Wen Liu, Le Wang, Wen-Hui Qiu, Qing Xu, Hong-Bing Xiang,  and Yong-Man Lv
53465-53481
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Development of hepatocellular cancer induced by long term low fat-high carbohydrate diet in a NAFLD/NASH mouse model

Development of hepatocellular cancer induced by long term low fat-high carbohydrate diet in a NAFLD/NASH mouse model

https://doi.org/10.18632/oncotarget.18585

Alessandra Tessitore, Valentina Mastroiaco, Antonella Vetuschi, Roberta Sferra, Simona Pompili, Germana Cicciarelli, Remo Barnabei, Daria Capece, Francesca Zazzeroni, Carlo Capalbo,  and Edoardo Alesse
53482-53494
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TLR4 interaction with LPS in glioma CD133+ cancer stem cells induces cell proliferation, resistance to chemotherapy and evasion from cytotoxic T lymphocyte-induced cytolysis

TLR4 interaction with LPS in glioma CD133+ cancer stem cells induces cell proliferation, resistance to chemotherapy and evasion from cytotoxic T lymphocyte-induced cytolysis

https://doi.org/10.18632/oncotarget.18586

Fengyuan Che, Jiawei Yin, Yanchun Quan, Xiaoli Xie, Xueyuan Heng, Yifeng Du,  and Lijuan Wang
53495-53507
Abstract  |  PDF  |  HTML  |  Order a Reprint

Structural basis of mutant-selectivity and drug-resistance related to CO-1686

Structural basis of mutant-selectivity and drug-resistance related to CO-1686

https://doi.org/10.18632/oncotarget.18588

Xiao-E Yan, Su-Jie Zhu, Ling Liang, Peng Zhao, Hwan Geun Choi,  and Cai-Hong Yun
53508-53517
Abstract  |  PDF  |  HTML  |  Order a Reprint

SHP2 negatively regulates HLA-ABC and PD-L1 expression via STAT1 phosphorylation in prostate cancer cells

SHP2 negatively regulates HLA-ABC and PD-L1 expression via STAT1 phosphorylation in prostate cancer cells

https://doi.org/10.18632/oncotarget.18591

Zhuqing Liu, Yu Zhao, Juemin Fang, Ran Cui, Yuanyuan Xiao,  and Qing Xu
53518-53530
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Compliance with the enhanced recovery after surgery protocol and prognosis after colorectal cancer surgery: A prospective cohort study

Compliance with the enhanced recovery after surgery protocol and prognosis after colorectal cancer surgery: A prospective cohort study

https://doi.org/10.18632/oncotarget.18602

Liang Li, Juying Jin, Su Min, Dan Liu,  and Ling Liu
53531-53541
Abstract  |  PDF  |  HTML  |  Order a Reprint

Value of quantitative magnetic resonance imaging T1-relaxometry in predicting contrast-enhancement in glioblastoma patients

Value of quantitative magnetic resonance imaging T1-relaxometry in predicting contrast-enhancement in glioblastoma patients

https://doi.org/10.18632/oncotarget.18612

Elke Hattingen, Andreas Müller, Alina Jurcoane, Burkhard Mädler, Philip Ditter, Hans Schild, Ulrich Herrlinger, Martin Glas,  and Sied Kebir
53542-53551
Abstract  |  PDF  |  HTML  |  Order a Reprint

A vitamin D receptor agonist converts CD4+ T cells to Foxp3+ regulatory T cells in patients with ulcerative colitis

A vitamin D receptor agonist converts CD4+ T cells to Foxp3+ regulatory T cells in patients with ulcerative colitis

https://doi.org/10.18632/oncotarget.18614

Dong Lu, Bin Lan, Zonren Din, Hang Chen,  and Guoqiang Chen
53552-53562
Abstract  |  PDF  |  HTML  |  Order a Reprint

The novel sphingosine-1-phosphate receptors antagonist AD2900 affects lymphocyte activation and inhibits T-cell entry into the lymph nodes

The novel sphingosine-1-phosphate receptors antagonist AD2900 affects lymphocyte activation and inhibits T-cell entry into the lymph nodes

https://doi.org/10.18632/oncotarget.18626

Jing Song, Arie Dagan, Zhanna Yakhtin, Shimon Gatt, Sean Riley, Hugh Rosen, Reuven Or,  and Osnat Almogi-Hazan
53563-53580
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

lncRNA H19 mediates BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) through Notch signaling

lncRNA H19 mediates BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) through Notch signaling

https://doi.org/10.18632/oncotarget.18655

Junyi Liao, Xinyi Yu, Xue Hu, Jiaming Fan, Jing Wang, Zhicai Zhang, Chen Zhao, Zongyue Zeng, Yi Shu, Ruyi Zhang, Shujuan Yan, Yasha Li, Wenwen Zhang, Jing Cui, Chao Ma, Li Li, Yichun Yu, Tingting Wu, Xingye Wu, Jiayan Lei, Jia Wang, Chao Yang, Ke Wu, Ying Wu, Jun Tang, Bai-Cheng He, Zhong-Liang Deng, Hue H. Luu, Rex C. Haydon, Russell R. Reid, Michael J. Lee, Jennifer Moriatis Wolf, Wei Huang,  and Tong-Chuan He
53581-53601
Abstract  |  PDF  |  HTML  |  Order a Reprint

Selective ATP hydrolysis inhibition in F1Fo ATP synthase enhances radiosensitivity in non-small-cell lung cancer cells (A549)

Selective ATP hydrolysis inhibition in F1Fo ATP synthase enhances radiosensitivity in non-small-cell lung cancer cells (A549)

https://doi.org/10.18632/oncotarget.18657

Yupei Wang, Qinzheng Hou, Guoqing Xiao, Shifeng Yang, Cuixia Di, Jing Si, Rong Zhou, Yancheng Ye, Yanshan Zhang,  and Hong Zhang
53602-53612
Abstract  |  PDF  |  HTML  |  Order a Reprint

XPG gene rs751402 C>T polymorphism and cancer risk: Evidence from 22 publications

XPG gene rs751402 C>T polymorphism and cancer risk: Evidence from 22 publications

https://doi.org/10.18632/oncotarget.19421

Haixia Zhou, Ting-Yan Shi, Wenwen Zhang, Qiwen Li, Jinhong Zhu, Jing He,  and Jichen Ruan
53613-53622
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Meta-Analysis

The prevalence of depression in rheumatoid arthritis in China: A systematic review

The prevalence of depression in rheumatoid arthritis in China: A systematic review

https://doi.org/10.18632/oncotarget.17323

Xin Fu, Zhi-Jun Li, Chun-Jun Yang, Liangshu Feng, Lemeng Sun, Yang Yao,  and Yu-Ting Huang
53623-53630
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The impact of primary tumor location on efficacy of cetuximab in metastatic colorectal cancer patients with different Kras status: a systematic review and meta-analysis

The impact of primary tumor location on efficacy of cetuximab in metastatic colorectal cancer patients with different Kras status: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.19022

De-Dong Cao, Hui-Lin Xu, Xi-Ming Xu,  and Wei Ge
53631-53641
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Prognostic value of molecular events from negative surgical margin of non-small-cell lung cancer

Prognostic value of molecular events from negative surgical margin of non-small-cell lung cancer

https://doi.org/10.18632/oncotarget.10949

Bangrong Cao, Lin Feng, Dan Lu, Yan Liu, Yu Liu, Suping Guo, Naijun Han, Xiangyang Liu, Yousheng Mao, Jie He, Shujun Cheng, Yanning Gao,  and Kaitai Zhang
53642-53653
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Decitabine-based chemotherapy followed by haploidentical lymphocyte infusion improves the effectiveness in elderly patients with acute myeloid leukemia

Decitabine-based chemotherapy followed by haploidentical lymphocyte infusion improves the effectiveness in elderly patients with acute myeloid leukemia

https://doi.org/10.18632/oncotarget.11183

Yu Jing, Xiangshu Jin, Lixin Wang, Liping Dou, Quanshun Wang, Yushi Yao, Shimei Lian, Jihao Zhou, Haiyan Zhu, Zilong Yao, Lijun Gao, Lili Wang, Yonghui Li, Xuefeng Bai, Meiyun Fang,  and Li Yu
53654-53663
Abstract  |  PDF  |  HTML  |  Order a Reprint

Tumor heterogeneity assessed by texture analysis on contrast-enhanced CT in lung adenocarcinoma: association with pathologic grade

Tumor heterogeneity assessed by texture analysis on contrast-enhanced CT in lung adenocarcinoma: association with pathologic grade

https://doi.org/10.18632/oncotarget.15399

Ying Liu, Shichang Liu, Fangyuan Qu, Qian Li, Runfen Cheng,  and Zhaoxiang Ye
53664-53674
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Efficacy of epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) in targeted therapy of lung squamous cell carcinoma patients with EGFR mutation: a pooled analysis

Efficacy of epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) in targeted therapy of lung squamous cell carcinoma patients with EGFR mutation: a pooled analysis

https://doi.org/10.18632/oncotarget.15726

Jingqi Zhuang, Yongfeng Yu, Ziming Li,  and Shun Lu
53675-53683
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Effect of age on long-term outcomes after stroke with atrial fibrillation: a hospital-based follow-up study in China

Effect of age on long-term outcomes after stroke with atrial fibrillation: a hospital-based follow-up study in China

https://doi.org/10.18632/oncotarget.15729

Tao Wang, Bin Li, Hongfei Gu, Yongzhong Lou, Xianjia Ning, Jinghua Wang,  and Zhongping An
53684-53690
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dynamic changes in serum cytokine levels and their clinical significance in predicting acute GVHD

Dynamic changes in serum cytokine levels and their clinical significance in predicting acute GVHD

https://doi.org/10.18632/oncotarget.15738

Chunyan Zhang, Wenrong Huang, Pengjun Zhang, Qingyi Zhang, Guanghong Guo, Feng Gu, Hua Yang, Yurong Wang, Xueliang Huang, Qian Jia,  and Yaping Tian
53691-53700
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Methotrexate plus idarubicin improves outcome of patients with primary central nervous system lymphoma

Methotrexate plus idarubicin improves outcome of patients with primary central nervous system lymphoma

https://doi.org/10.18632/oncotarget.15899

Ni Fan, Lu Zhang, Xiaoping Xu, Bobin Chen, Chen Zhu, Pei Li, Zi Chen, Tianling Ding, Yan Ma, Yan Yuan,  and Zhiguang Lin
53701-53713
Abstract  |  PDF  |  HTML  |  Order a Reprint

Gender differences in fibrosis remodeling in patients with long-standing persistent atrial fibrillation

Gender differences in fibrosis remodeling in patients with long-standing persistent atrial fibrillation

https://doi.org/10.18632/oncotarget.16342

Zhi Li, Zengwei Wang, Zongtao Yin, Yuji Zhang, Xiaodong Xue, Jinsong Han, Yan Zhu, Jian Zhang, Maximilian Y. Emmert,  and Huishan Wang
53714-53729
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Safety and efficacy of p62 DNA vaccine ELENAGEN in a first-in-human trial in patients with advanced solid tumors

Safety and efficacy of p62 DNA vaccine ELENAGEN in a first-in-human trial in patients with advanced solid tumors

https://doi.org/10.18632/oncotarget.16574

Dmitry M. Ponomarenko, Irina D. Klimova, Yulia A. Chapygina, Viktoria V. Dvornichenko, Natalia V. Zhukova, Rashida V. Orlova, Georgy M. Manikhas, Alexandr V. Zyryanov, Lilya A. Burkhanova, Irina I. Badrtdinova, Basile N. Oshchepkov, Elena V. Filippova, Sergei V. Orlov, Sergei I. Kolesnikov, Albert A. Sufianov, Svetlana R. Baum, Olga Y. Zaitzeva, Andrey B. Komissarov, Mikhail P. Grudinin, Oleg I. Kiselev, Anatoly F. Tsyb, Franco Venanzi, Vita Shcherbinina, Andrey Chursov, Vladimir L. Gabai,  and Alexander M. Shneider
53730-53739
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

To predict the radiosensitivity of nasopharyngeal carcinoma using intravoxel incoherent motion MRI at 3.0 T

To predict the radiosensitivity of nasopharyngeal carcinoma using intravoxel incoherent motion MRI at 3.0 T

https://doi.org/10.18632/oncotarget.17367

Wen Bo Chen, Bin Zhang, Long Liang, Yu Hao Dong, Guan Hui Cai, Chang Hong Liang, Bo Wen Lan,  and Shui Xing Zhang
53740-53750
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

Biomarkers for early diagnosis of malignant mesothelioma: Do we need another moonshot?

Biomarkers for early diagnosis of malignant mesothelioma: Do we need another moonshot?

https://doi.org/10.18632/oncotarget.17910

Sabrina Lagniau, Kevin Lamote, Jan P. van Meerbeeck,  and Karim Y. Vermaelen
53751-53762
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Advances in single-cell RNA sequencing and its applications in cancer research

Advances in single-cell RNA sequencing and its applications in cancer research

https://doi.org/10.18632/oncotarget.17893

Sibo Zhu, Tao Qing, Yuanting Zheng,  and Leming Shi
53763-53779
Abstract  |  PDF  |  HTML  |  Order a Reprint

Transforming growth factor β: A potential biomarker and therapeutic target of ventricular remodeling

Transforming growth factor β: A potential biomarker and therapeutic target of ventricular remodeling

https://doi.org/10.18632/oncotarget.17255

Yuan Ma, Hai Zou, Xing-Xing Zhu, Jie Pang, Qiang Xu, Qin-Yang Jin, Ya-Hui Ding, Bing Zhou,  and Dong-Sheng Huang
53780-53790
Abstract  |  PDF  |  HTML  |  Order a Reprint

The involvement of DARPP-32 in the pathophysiology of schizophrenia

The involvement of DARPP-32 in the pathophysiology of schizophrenia

https://doi.org/10.18632/oncotarget.17339

Haitao Wang, Mohd Farhan, Jiangping Xu, Philip Lazarovici,  and Wenhua Zheng
53791-53803
Abstract  |  PDF  |  HTML  |  Order a Reprint

Epigenetic dynamics and interplay during spermatogenesis and embryogenesis: implications for male fertility and offspring health

Epigenetic dynamics and interplay during spermatogenesis and embryogenesis: implications for male fertility and offspring health

https://doi.org/10.18632/oncotarget.17479

Shao-Qin Ge, Sheng-Li Lin, Zheng-Hui Zhao,  and Qing-Yuan Sun
53804-53818
Abstract  |  PDF  |  HTML  |  Order a Reprint

Succinate: An initiator in tumorigenesis and progression

Succinate: An initiator in tumorigenesis and progression

https://doi.org/10.18632/oncotarget.17734

Ting Zhao, Xianmin Mu,  and Qiang You
53819-53828
Abstract  |  PDF  |  HTML  |  Order a Reprint

Microbiota-gut-brain axis and the central nervous system

Microbiota-gut-brain axis and the central nervous system

https://doi.org/10.18632/oncotarget.17754

Xiqun Zhu, Yong Han, Jing Du, Renzhong Liu, Ketao Jin,  and Wei Yi
53829-53838
Abstract  |  PDF  |  HTML  |  Order a Reprint

The role of Notch signaling in gastric carcinoma: molecular pathogenesis and novel therapeutic targets

The role of Notch signaling in gastric carcinoma: molecular pathogenesis and novel therapeutic targets

https://doi.org/10.18632/oncotarget.17809

Yizheng Yao, Ying Ni, Jiawen Zhang, Hua Wang,  and Shihe Shao
53839-53853
Abstract  |  PDF  |  HTML  |  Order a Reprint

Strategies targeting angiogenesis in advanced non-small cell lung cancer

Strategies targeting angiogenesis in advanced non-small cell lung cancer

https://doi.org/10.18632/oncotarget.17957

Jun Wang, Jianpeng Chen, Yan Guo, Baocheng Wang,  and Huili Chu
53854-53872
Abstract  |  PDF  |  HTML  |  Order a Reprint

Meta-Analysis

Genetic association between TNF-α promoter polymorphism and susceptibility to squamous cell carcinoma, basal cell carcinoma, and melanoma: A meta-analysis

Genetic association between TNF-α promoter polymorphism and susceptibility to squamous cell carcinoma, basal cell carcinoma, and melanoma: A meta-analysis

https://doi.org/10.18632/oncotarget.17179

Ning Liu, Guang-Jing Liu,  and Juan Liu
53873-53885
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Corrections

Correction: Deciphering the role of nuclear and cytoplasmic IKKα in skin cancer

Correction: Deciphering the role of nuclear and cytoplasmic IKKα in skin cancer

https://doi.org/10.18632/oncotarget.20001

Josefa P. Alameda, Miriam Gaspar, Ángel Ramírez, Manuel Navarro, Angustias Page, Cristian Suárez-Cabrera, M. Guadalupe Fernández, Jose R. Mérida, Jesús M. Paramio, Rosa A. García-Fernández, M. Jesús Fernández-Aceñero,  and M. Llanos Casanova
53886-53886
Correction  |  PDF

Correction: IKKα regulates the stratification and differentiation of the epidermis: implications for skin cancer development

Correction: IKKα regulates the stratification and differentiation of the epidermis: implications for skin cancer development

https://doi.org/10.18632/oncotarget.20002

Josefa P. Alameda, Manuel Navarro, Ángel Ramírez, Angustias Page, Cristian Suárez-Cabrera, Dong-Ming Su, Jesús M. Paramio, María del Carmen Fariña, Marcela Del Río, María Jesús Fernández-Aceñero, Ana Bravo,  and María de los Llanos Casanova
53887-53887
Correction  |  PDF


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