Oncotarget

Vol 8, No 27

July 4, 2017

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About The Cover

The cover for issue 27 of Oncotarget features Figure 4A, "Loss of TMEM192 does not impair lysosomal function in TMEM192-deficient murine embryonic fibroblasts (MEFs)," from Nguyen, et al.

Table of Contents

News

Sphingosine kinase 2 and multiple myeloma

Sphingosine kinase 2 and multiple myeloma

https://doi.org/10.18632/oncotarget.17420

Nigel J. Pyne,  and Susan Pyne
43596-43597
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Olaparib and somatic BRCA mutations

Olaparib and somatic BRCA mutations

https://doi.org/10.18632/oncotarget.18419

Angela George, Susana Banerjee,  and Stan Kaye
43598-43599
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T315I+ tyrosine-kinase independent CML cells resistance

T315I+ tyrosine-kinase independent CML cells resistance

https://doi.org/10.18632/oncotarget.18573

Franck Emmanuel Nicolini, Elodie Grockowiak,  and Véronique Maguer-Satta
43600-43601
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Priority Research Papers

Sphingosine kinase 2 inhibition synergises with bortezomib to target myeloma by enhancing endoplasmic reticulum stress

Sphingosine kinase 2 inhibition synergises with bortezomib to target myeloma by enhancing endoplasmic reticulum stress

https://doi.org/10.18632/oncotarget.17115

Craig T. Wallington-Beddoe, Melissa K. Bennett, Kate Vandyke, Lorena Davies, Julia R. Zebol, Paul A.B. Moretti, Melissa R. Pitman, Duncan R. Hewett, Andrew C.W. Zannettino,  and Stuart M. Pitson
43602-43616
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Chronic diabetic states worsen Alzheimer neuropathology and cognitive deficits accompanying disruption of calcium signaling in leptin-deficient APP/PS1 mice

Chronic diabetic states worsen Alzheimer neuropathology and cognitive deficits accompanying disruption of calcium signaling in leptin-deficient APP/PS1 mice

https://doi.org/10.18632/oncotarget.17116

Shuai Zhang, Rui Chai, Ying-Ying Yang, Shi-Qi Guo, Shan Wang, Tian Guo, Shuang-Feng Xu, Yan-Hui Zhang, Zhan-You Wang,  and Chuang Guo
43617-43634
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Functional characterization of the lysosomal membrane protein TMEM192 in mice

Functional characterization of the lysosomal membrane protein TMEM192 in mice

https://doi.org/10.18632/oncotarget.17514

Thuy Linh Nguyen, Janna Schneppenheim, Sönke Rudnik, Renate Lüllmann-Rauch, Christian Bernreuther, Irm Hermans-Borgmeyer, Markus Glatzel, Paul Saftig,  and Bernd Schröder
43635-43652
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Biological and clinical evidence for somatic mutations in BRCA1 and BRCA2 as predictive markers for olaparib response in high-grade serous ovarian cancers in the maintenance setting

Biological and clinical evidence for somatic mutations in BRCA1 and BRCA2 as predictive markers for olaparib response in high-grade serous ovarian cancers in the maintenance setting

https://doi.org/10.18632/oncotarget.17613

Brian A. Dougherty, Zhongwu Lai, Darren R. Hodgson, Maria C.M. Orr, Matthew Hawryluk, James Sun, Roman Yelensky, Stuart K. Spencer, Jane D. Robertson, Tony W. Ho, Anitra Fielding, Jonathan A. Ledermann,  and J. Carl Barrett
43653-43661
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Targeting BCR-ABL+ stem/progenitor cells and BCR-ABL-T315I mutant cells by effective inhibition of the BCR-ABL-Tyr177-GRB2 complex

Targeting BCR-ABL+ stem/progenitor cells and BCR-ABL-T315I mutant cells by effective inhibition of the BCR-ABL-Tyr177-GRB2 complex

https://doi.org/10.18632/oncotarget.18216

Min Chen, Ali G. Turhan, Hongxia Ding, Qingcong Lin, Kun Meng,  and Xiaoyan Jiang
43662-43677
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Biological specificity of CDK4/6 inhibitors: dose response relationship, in vivo signaling, and composite response signature

Biological specificity of CDK4/6 inhibitors: dose response relationship, in vivo signaling, and composite response signature

https://doi.org/10.18632/oncotarget.18435

Erik S. Knudsen, Jack Hutcheson, Paris Vail,  and Agnieszka K. Witkiewicz
43678-43691
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Mitochondrial ASncmtRNA-1 and ASncmtRNA-2 as potent targets to inhibit tumor growth and metastasis in the RenCa murine renal adenocarcinoma model

Mitochondrial ASncmtRNA-1 and ASncmtRNA-2 as potent targets to inhibit tumor growth and metastasis in the RenCa murine renal adenocarcinoma model

https://doi.org/10.18632/oncotarget.18460

Vincenzo Borgna, Jaime Villegas, Verónica A. Burzio, Sebastián Belmar, Mariela Araya, Emanuel Jeldes, Lorena Lobos-González, Verónica Silva, Claudio Villota, Luciana Oliveira-Cruz, Constanza Lopez, Teresa Socias, Octavio Castillo,  and Luis O. Burzio
43692-43708
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Research Papers: Gerotarget (Focus on Aging)

The protective effect of Epimedii Folium and Curculiginis Rhizoma on Alzheimer’s disease by the inhibitions of NF-κB/MAPK pathway and NLRP3 inflammasome

The protective effect of Epimedii Folium and Curculiginis Rhizoma on Alzheimer’s disease by the inhibitions of NF-κB/MAPK pathway and NLRP3 inflammasome

https://doi.org/10.18632/oncotarget.12574

Zhou Lan, Guangjing Xie, Meng Wei, Ping Wang,  and Lvyi Chen
43709-43720
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Research Papers

Updated meta-analysis of the role of APOE ε2/ε3/ε4 alleles in frontotemporal lobar degeneration

Updated meta-analysis of the role of APOE ε2/ε3/ε4 alleles in frontotemporal lobar degeneration

https://doi.org/10.18632/oncotarget.17341

Wen-Hua Su, Zhi-Hong Shi, Shu-Ling Liu, Xiao-Dan Wang, Shuai Liu,  and Yong Ji
43721-43732
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Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway

Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway

https://doi.org/10.18632/oncotarget.16376

Koji Ando, Ankur K. Shah, Vibhu Sachdev, Benjamin P. Kleinstiver, Julian Taylor-Parker, Moira M. Welch, Yiheng Hu, Ravi Salgia, Forest M. White, Jeffrey D. Parvin, Al Ozonoff, Lucia E. Rameh, J. Keith Joung,  and Ajit K. Bharti
43733-43751
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Whole-exome sequencing identified genetic risk factors for asparaginase-related complications in childhood ALL patients

Whole-exome sequencing identified genetic risk factors for asparaginase-related complications in childhood ALL patients

https://doi.org/10.18632/oncotarget.17959

Rachid Abaji, Vincent Gagné, Chang Jiang Xu, Jean-François Spinella, Francesco Ceppi, Caroline Laverdière, Jean-Marie Leclerc, Stephen E. Sallan, Donna Neuberg, Jeffery L. Kutok, Lewis B. Silverman, Daniel Sinnett,  and Maja Krajinovic
43752-43767
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LncRNA RSU1P2 contributes to tumorigenesis by acting as a ceRNA against let-7a in cervical cancer cells

LncRNA RSU1P2 contributes to tumorigenesis by acting as a ceRNA against let-7a in cervical cancer cells

https://doi.org/10.18632/oncotarget.10844

Qian Liu, Xu Guo, Shengshun Que, Xi Yang, Hongxia Fan, Min Liu, Xin Li,  and Hua Tang
43768-43781
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Recombinant TAT-BMI-1 fusion protein induces ex vivo expansion of human umbilical cord blood-derived hematopoietic stem cells

Recombinant TAT-BMI-1 fusion protein induces ex vivo expansion of human umbilical cord blood-derived hematopoietic stem cells

https://doi.org/10.18632/oncotarget.15156

Bruna Codispoti, Nicola Rinaldo, Emanuela Chiarella, Michela Lupia, Cristina Barbara Spoleti, Maria Grazia Marafioti, Annamaria Aloisio, Stefania Scicchitano, Marco Giordano, Giovanna Nappo, Valeria Lucchino, Malcolm A.S. Moore, Pengbo Zhou, Maria Mesuraca, Heather Mandy Bond,  and Giovanni Morrone
43782-43798
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Resveratrol alleviates FFA and CCl4 induced apoptosis in HepG2 cells via restoring endoplasmic reticulum stress

Resveratrol alleviates FFA and CCl4 induced apoptosis in HepG2 cells via restoring endoplasmic reticulum stress

https://doi.org/10.18632/oncotarget.16460

Fenghua Li, Yang Yang, Lili Yang, Kai Wang, Xing Zhang, Yunlong Zong, Yixin Ding, Changhong Wang, Li Zhang,  and Guang Ji
43799-43809
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inFRank: a ranking-based identification of influential genes in biological networks

inFRank: a ranking-based identification of influential genes in biological networks

https://doi.org/10.18632/oncotarget.11878

Xiuliang Cui, Xiaofeng Li, Jing Li, Xue Wang, Wen Sun, Zhuo Cheng, Jin Ding,  and Hongyang Wang
43810-43821
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Rabies viruses leader RNA interacts with host Hsc70 and inhibits virus replication

Rabies viruses leader RNA interacts with host Hsc70 and inhibits virus replication

https://doi.org/10.18632/oncotarget.16517

Ran Zhang, Chuangang Liu, Yunzi Cao, Muhammad Jamal, Xi Chen, Jinfang Zheng, Liang Li, Jing You, Qi Zhu, Shiyong Liu, Jinxia Dai, Min Cui, Zhen F. Fu,  and Gang Cao
43822-43837
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cell cycle protein Bora serves as a novel poor prognostic factor in multiple adenocarcinomas

Cell cycle protein Bora serves as a novel poor prognostic factor in multiple adenocarcinomas

https://doi.org/10.18632/oncotarget.16631

Qiong-Xia Zhang, Rui Gao, Jin Xiang, Zhong-Yu Yuan, Yuan-Min Qian, Min Yan, Zi-Feng Wang, Quentin Liu, Hai-Dong Zhao,  and Chang-Hong Liu
43838-43852
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumor suppressor BLU promotes TRAIL-induced apoptosis by downregulating NF-κB signaling in nasopharyngeal carcinoma

Tumor suppressor BLU promotes TRAIL-induced apoptosis by downregulating NF-κB signaling in nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.14126

Jiahui Zhou, Zunnan Huang, Ziyou Wang, Shumin Liu, Alf Grandien, Ingemar Ernberg, Zhiwei He,  and Xiangning Zhang
43853-43865
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Development of diagnostic SCAR markers for genomic DNA amplifications in breast carcinoma by DNA cloning of high-GC RAMP-PCR fragments

Development of diagnostic SCAR markers for genomic DNA amplifications in breast carcinoma by DNA cloning of high-GC RAMP-PCR fragments

https://doi.org/10.18632/oncotarget.16704

Shangyi Fu, Jingliang Cheng, Chunli Wei, Luquan Yang, Xiuli Xiao, Dianzheng Zhang, M. David Stewart,  and Junjiang Fu
43866-43877
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Hsa_circ_0005986 inhibits carcinogenesis by acting as a miR-129-5p sponge and is used as a novel biomarker for hepatocellular carcinoma

Hsa_circ_0005986 inhibits carcinogenesis by acting as a miR-129-5p sponge and is used as a novel biomarker for hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.16709

Liyun Fu, Qingqing Chen, Ting Yao, Tianwen Li, Sheng Ying, Yaoren Hu,  and Junming Guo
43878-43888
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MDI 301, a synthetic retinoid, depressed levels of matrix metalloproteinases and oxidative stress in diabetic dermal fibroblasts

MDI 301, a synthetic retinoid, depressed levels of matrix metalloproteinases and oxidative stress in diabetic dermal fibroblasts

https://doi.org/10.18632/oncotarget.16803

Jianhua Zhai,  and Yuli Wang
43889-43896
Abstract  |  PDF  |  HTML  |  Order a Reprint

miRNA-1246 induces pro-inflammatory responses in mesenchymal stem/stromal cells by regulating PKA and PP2A

miRNA-1246 induces pro-inflammatory responses in mesenchymal stem/stromal cells by regulating PKA and PP2A

https://doi.org/10.18632/oncotarget.14915

Alexander Bott, Nese Erdem, Shalom Lerrer, Agnes Hotz-Wagenblatt, Christian Breunig, Khalid Abnaof, Angelika Worner, Heike Wilhelm, Ewald Munstermann, Adit Ben-Baruch,  and Stefan Wiemann
43897-43914
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A meta-analysis of HLA peptidome composition in different hematological entities: entity-specific dividing lines and "pan-leukemia" antigens

A meta-analysis of HLA peptidome composition in different hematological entities: entity-specific dividing lines and "pan-leukemia" antigens

https://doi.org/10.18632/oncotarget.14918

Linus Backert, Daniel Johannes Kowalewski, Simon Walz, Heiko Schuster, Claudia Berlin, Marian Christoph Neidert, Mirle Schemionek, Tim H. Brummendorf, Vladan Vucinic, Dietger Niederwieser, Lothar Kanz, Helmut Rainer Salih, Oliver Kohlbacher, Katja Weisel, Hans-Georg Rammensee, Stefan Stevanovic,  and Juliane Sarah Walz
43915-43924
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Risk of hepatitis C virus related hepatocellular carcinoma between subjects with spontaneous and treatment-induced viral clearance

Risk of hepatitis C virus related hepatocellular carcinoma between subjects with spontaneous and treatment-induced viral clearance

https://doi.org/10.18632/oncotarget.14937

Chung-Feng Huang, Ming-Lun Yeh, Ching-I Huang, Yu-Ju Lin, Pei-Chien Tsai, Zu-Yau Lin, Soa-Yu Chan, Shinn-Cherng Chen, Hwai-I Yang, Jee-Fu Huang, Sheng-Nan Lu, Chia-Yen Dai, Chin-Lan Jen, Yong Yuan, Gilbert L'Italien, Li-Yu Wang, Mei-Hsuan Lee, Ming-Lung Yu, Wan-Long Chuang,  and Chien-Jen Chen
43925-43933
Abstract  |  PDF  |  HTML  |  Order a Reprint

Exome-based genome-wide association study and risk assessment using genetic risk score to prostate cancer in the Korean population

Exome-based genome-wide association study and risk assessment using genetic risk score to prostate cancer in the Korean population

https://doi.org/10.18632/oncotarget.16540

Jong Jin Oh, Soo Ji Lee, Joo-Yeon Hwang, Dokyoon Kim, Sang Eun Lee, Sung Kyu Hong, Jin-Nyoung Ho, Sungroh Yoon, Joohon Sung, Wun-Jae Kim,  and Seok-Soo Byun
43934-43943
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circulating asymmetric dimethylarginine and the risk of preeclampsia: a meta-analysis based on 1338 participants

Circulating asymmetric dimethylarginine and the risk of preeclampsia: a meta-analysis based on 1338 participants

https://doi.org/10.18632/oncotarget.16543

Jing Yuan, Xinguo Wang, Yudou Xie, Yuzhi Wang, Lei Dong, Hong Li,  and Tongyu Zhu
43944-43952
Abstract  |  PDF  |  HTML  |  Order a Reprint

SNORD47, a box C/D snoRNA, suppresses tumorigenesis in glioblastoma

SNORD47, a box C/D snoRNA, suppresses tumorigenesis in glioblastoma

https://doi.org/10.18632/oncotarget.16693

Bin Xu, Min-Hua Ye, Shi-Gang Lv, Qi-Xue Wang, Miao-Jing Wu, Bing Xiao, Chun-Sheng Kang,  and Xin-Gen Zhu
43953-43966
Abstract  |  PDF  |  HTML  |  Order a Reprint

Exploring the key genes and pathways in enchondromas using a gene expression microarray

Exploring the key genes and pathways in enchondromas using a gene expression microarray

https://doi.org/10.18632/oncotarget.16700

Zhongju Shi, Hengxing Zhou, Bin Pan, Lu Lu, Yi Kang, Lu Liu, Zhijian Wei,  and Shiqing Feng
43967-43977
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical verification of plasma messenger RNA as novel noninvasive biomarker identified through bioinformatics analysis for lung cancer

Clinical verification of plasma messenger RNA as novel noninvasive biomarker identified through bioinformatics analysis for lung cancer

https://doi.org/10.18632/oncotarget.16701

Dan Zhou, Weiwei Tang, Xinli Liu, Han-Xiang An,  and Yun Zhang
43978-43989
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Variant 2 of KIAA0101, antagonizing its oncogenic variant 1, might be a potential therapeutic strategy in hepatocellular carcinoma

Variant 2 of KIAA0101, antagonizing its oncogenic variant 1, might be a potential therapeutic strategy in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.16702

Lijuan Liu, Youyi Liu, Xiaobei Chen, Miao Wang, Yan Zhou, Ping Zhou, Wenxin Li,  and Fan Zhu
43990-44003
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Radioimmunotherapy for CD133(+) colonic cancer stem cells inhibits tumor development in nude mice

Radioimmunotherapy for CD133(+) colonic cancer stem cells inhibits tumor development in nude mice

https://doi.org/10.18632/oncotarget.16868

Weng Dinghu, Jin Xueyan, Qin Saimei, Lan Xiaoli, Chen Chong, Sun Xun, She Xianliang, Dong Changling,  and An Rui
44004-44014
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Survival benefit of glioblastoma patients after FDA approval of temozolomide concomitant with radiation and bevacizumab: A population-based study

Survival benefit of glioblastoma patients after FDA approval of temozolomide concomitant with radiation and bevacizumab: A population-based study

https://doi.org/10.18632/oncotarget.17054

Ping Zhu, Xianglin L. Du, Guangrong Lu,  and Jay-Jiguang Zhu
44015-44031
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nano-pulse stimulation (NPS) ablate tumors and inhibit lung metastasis on both canine spontaneous osteosarcoma and murine transplanted hepatocellular carcinoma with high metastatic potential

Nano-pulse stimulation (NPS) ablate tumors and inhibit lung metastasis on both canine spontaneous osteosarcoma and murine transplanted hepatocellular carcinoma with high metastatic potential

https://doi.org/10.18632/oncotarget.17178

Xinhua Chen, Yiling Chen, Jianwen Jiang, Liming Wu, Shengyong Yin, Xudong Miao, R. James Swanson,  and Shusen Zheng
44032-44039
Abstract  |  PDF  |  HTML  |  Order a Reprint

The combination of prostate imaging reporting and data system version 2 (PI-RADS v2) and periprostatic fat thickness on multi-parametric MRI to predict the presence of prostate cancer

The combination of prostate imaging reporting and data system version 2 (PI-RADS v2) and periprostatic fat thickness on multi-parametric MRI to predict the presence of prostate cancer

https://doi.org/10.18632/oncotarget.17182

Yudong Cao, Min Cao, Yuke Chen, Wei Yu, Yu Fan, Qing Liu, Ge Gao, Zheng Zhao, Xiaoying Wang,  and Jie Jin
44040-44049
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circulating miR-21 serves as a serum biomarker for hepatocellular carcinoma and correlated with distant metastasis

Circulating miR-21 serves as a serum biomarker for hepatocellular carcinoma and correlated with distant metastasis

https://doi.org/10.18632/oncotarget.17211

Xin Guo, Xiaohui Lv, Xing Lv, Yueyun Ma, Lin Chen,  and Yong Chen
44050-44058
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Simultaneous in vitro generation of CD8 and CD4 T cells specific to three universal tumor associated antigens of WT1, survivin and TERT and adoptive T cell transfer for the treatment of acute myeloid leukemia

Simultaneous in vitro generation of CD8 and CD4 T cells specific to three universal tumor associated antigens of WT1, survivin and TERT and adoptive T cell transfer for the treatment of acute myeloid leukemia

https://doi.org/10.18632/oncotarget.17212

Hyun-Jung Sohn, Ji Yoon Lee, Hyun-Joo Lee, Dae-Hee Sohn, Hyun-Il Cho, Hee-Je Kim,  and Tai-Gyu Kim
44059-44072
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Olaparib in combination with irinotecan, cisplatin, and mitomycin C in patients with advanced pancreatic cancer

Olaparib in combination with irinotecan, cisplatin, and mitomycin C in patients with advanced pancreatic cancer

https://doi.org/10.18632/oncotarget.17237

Mark Yarchoan, Melinda C. Myzak, Burles A. Johnson III, Ana De Jesus-Acosta, Dung T. Le, Elizabeth M. Jaffee, Nilofer S. Azad, Ross C. Donehower, Lei Zheng, Paul E. Oberstein, Robert L. Fine, Daniel A. Laheru,  and Michael Goggins
44073-44081
Abstract  |  PDF  |  HTML  |  Order a Reprint

POU2F1 over-expression correlates with poor prognoses and promotes cell growth and epithelial-to-mesenchymal transition in hepatocellular carcinoma

POU2F1 over-expression correlates with poor prognoses and promotes cell growth and epithelial-to-mesenchymal transition in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.17296

Yonghao Zhong, Hongyang Huang, Min Chen, Jinzhou Huang, Qingxia Wu, Guang-Rong Yan,  and De Chen
44082-44095
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of circular RNAs as a promising new class of diagnostic biomarkers for human breast cancer

Identification of circular RNAs as a promising new class of diagnostic biomarkers for human breast cancer

https://doi.org/10.18632/oncotarget.17307

Lingshuang Lü, Jian Sun, Peiyi Shi, Weimin Kong, Kun Xu, Biyu He, Simin Zhang,  and Jianming Wang
44096-44107
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Modulation of goat monocyte function by HCcyst-2, a secreted cystatin from Haemonchus contortus

Modulation of goat monocyte function by HCcyst-2, a secreted cystatin from Haemonchus contortus

https://doi.org/10.18632/oncotarget.17308

Yujian Wang, Yuling Wen, Shuai Wang, Muhammad Ehsan, RuoFeng Yan, XiaoKai Song, LiXin Xu,  and XiangRui Li
44108-44120
Abstract  |  PDF  |  HTML  |  Order a Reprint

A phase II trial of regorafenib in patients with metastatic and/or a unresectable gastrointestinal stromal tumor harboring secondary mutations of exon 17

A phase II trial of regorafenib in patients with metastatic and/or a unresectable gastrointestinal stromal tumor harboring secondary mutations of exon 17

https://doi.org/10.18632/oncotarget.17310

Chun-Nan Yeh, Ming-Huang Chen, Yen-Yang Chen, Ching-Yao Yang, Chueh-Chuan Yen, Chin-Yuan Tzen, Li-Tzong Chen,  and Jen-Shi Cen
44121-44130
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Radium-223 for primary bone metastases in patients with hormone-sensitive prostate cancer after radical prostatectomy

Radium-223 for primary bone metastases in patients with hormone-sensitive prostate cancer after radical prostatectomy

https://doi.org/10.18632/oncotarget.17311

Vera Wenter, Annika Herlemann, Wolfgang P. Fendler, Harun Ilhan, Natalia Tirichter, Peter Bartenstein, Christian G. Stief, Christian la Fougère, Nathalie L. Albert, Axel Rominger,  and Christian Gratzke
44131-44140
Abstract  |  PDF  |  HTML  |  Order a Reprint

Differentially expressed proteins in glioblastoma multiforme identified with a nanobody-based anti-proteome approach and confirmed by OncoFinder as possible tumor-class predictive biomarker candidates

Differentially expressed proteins in glioblastoma multiforme identified with a nanobody-based anti-proteome approach and confirmed by OncoFinder as possible tumor-class predictive biomarker candidates

https://doi.org/10.18632/oncotarget.17390

Ivana Jovčevska, Neja Zupanec, Žiga Urlep, Andrej Vranič, Boštjan Matos, Clara Limbaeck Stokin, Serge Muyldermans, Michael P. Myers, Anton A. Buzdin, Ivan Petrov,  and Radovan Komel
44141-44158
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epigenetic modifiers upregulate MHC II and impede ovarian cancer tumor growth

Epigenetic modifiers upregulate MHC II and impede ovarian cancer tumor growth

https://doi.org/10.18632/oncotarget.17395

Taylor B. Turner, Selene Meza-Perez, Angelina Londoño, Ashwini Katre, Jacelyn E. Peabody, Haller J. Smith, Andres Forero, Lyse A. Norian, J. Michael Straughn Jr, Donald J. Buchsbaum, Troy D. Randall,  and Rebecca C. Arend
44159-44170
Abstract  |  PDF  |  HTML  |  Order a Reprint

Knockdown of PKM2 and GLS1 expression can significantly reverse oxaliplatin-resistance in colorectal cancer cells

Knockdown of PKM2 and GLS1 expression can significantly reverse oxaliplatin-resistance in colorectal cancer cells

https://doi.org/10.18632/oncotarget.17396

Wei-Qun Lu, Ying-Ying Hu, Xiao-Ping Lin,  and Wei Fan
44171-44185
Abstract  |  PDF  |  HTML  |  Order a Reprint

IRF5 is associated with adverse postoperative prognosis of patients with non-metastatic clear cell renal cell carcinoma

IRF5 is associated with adverse postoperative prognosis of patients with non-metastatic clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.17777

Qi Bai, Li Liu, Yu Xia, Jiajun Wang, Wei Xi, Yang Qu, Ying Xiong, Qilai Long, Jiejie Xu,  and Jianming Guo
44186-44194
Abstract  |  PDF  |  HTML  |  Order a Reprint

DDX11-AS1 as potential therapy targets for human hepatocellular carcinoma

DDX11-AS1 as potential therapy targets for human hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.17409

Min Shi, Xiao-Yu Zhang, Heguo Yu, Shi-Hao Xiang, Ling Xu, Jue Wei, Qiong Wu, Rongrong Jia, Yu-Gang Wang,  and Xiao-Jie Lu
44195-44202
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Risk of cancer in patients with heart failure who use digoxin: a 10-year follow-up study and cell-based verification

Risk of cancer in patients with heart failure who use digoxin: a 10-year follow-up study and cell-based verification

https://doi.org/10.18632/oncotarget.17410

Min-Huey Chung, Yi-Wen Wang, Yung-Lung Chang, Shih-Ming Huang,  and Wei-Shiang Lin
44203-44216
Abstract  |  PDF  |  HTML  |  Order a Reprint

Urinary exosomes reveal protein signatures in hypertensive patients with albuminuria

Urinary exosomes reveal protein signatures in hypertensive patients with albuminuria

https://doi.org/10.18632/oncotarget.17787

Laura Gonzalez-Calero, Paula J. Martínez, Marta Martin-Lorenzo, Montserrat Baldan-Martin, Gema Ruiz-Hurtado, Fernando de la Cuesta, Eva Calvo, Julian Segura, Juan Antonio Lopez, Jesús Vázquez, Maria G. Barderas, Luis M. Ruilope, Fernando Vivanco,  and Gloria Alvarez-Llamas
44217-44231
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Synergistic targeting of malignant pleural mesothelioma cells by MDM2 inhibitors and TRAIL agonists

Synergistic targeting of malignant pleural mesothelioma cells by MDM2 inhibitors and TRAIL agonists

https://doi.org/10.18632/oncotarget.17790

Loredana Urso, Ilaria Cavallari, Micol Silic-Benussi, Lorena Biasini, Giulia Zago, Fiorella Calabrese, Pier Franco Conte, Vincenzo Ciminale,  and Giulia Pasello
44232-44241
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

An herbal formula attenuates collagen-induced arthritis via inhibition of JAK2-STAT3 signaling and regulation of Th17 cells in mice

An herbal formula attenuates collagen-induced arthritis via inhibition of JAK2-STAT3 signaling and regulation of Th17 cells in mice

https://doi.org/10.18632/oncotarget.17797

Xin Wu, Qiyang Shou, Cuiwei Chen, Hao Cai, Jida Zhang, Songqi Tang, Baochang Cai, Dongxin Tang,  and Gang Cao
44242-44254
Abstract  |  PDF  |  HTML  |  Order a Reprint

Structure based discovery of clomifene as a potent inhibitor of cancer-associated mutant IDH1

Structure based discovery of clomifene as a potent inhibitor of cancer-associated mutant IDH1

https://doi.org/10.18632/oncotarget.17464

Mengzhu Zheng, Weiguang Sun, Suyu Gao, Shanshan Luan, Dan Li, Renqi Chen, Qian Zhang, Lixia Chen, Jiangeng Huang,  and Hua Li
44255-44265
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Leflunomide/teriflunomide inhibit Epstein-Barr virus (EBV)-induced lymphoproliferative disease and lytic viral replication

Leflunomide/teriflunomide inhibit Epstein-Barr virus (EBV)-induced lymphoproliferative disease and lytic viral replication

https://doi.org/10.18632/oncotarget.17863

Andrea Bilger, Julie Plowshay, Shidong Ma, Dhananjay Nawandar, Elizabeth A. Barlow, James C. Romero-Masters, Jillian A. Bristol, Zhe Li, Ming-Han Tsai, Henri-Jacques Delecluse,  and Shannon C. Kenney
44266-44280
Abstract  |  PDF  |  HTML  |  Order a Reprint

The optimization of cell therapy by combinational application with apicidin-treated mesenchymal stem cells after myocardial infarction

The optimization of cell therapy by combinational application with apicidin-treated mesenchymal stem cells after myocardial infarction

https://doi.org/10.18632/oncotarget.17471

Dong Im Cho, Wan Seok Kang, Moon Hwa Hong, Hye Jin Kang, Mi Ra Kim, Min Chul Kim, Yong Sook Kim,  and Youngkeun Ahn
44281-44294
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting ERK enhances the cytotoxic effect of the novel PI3K and mTOR dual inhibitor VS-5584 in preclinical models of pancreatic cancer

Targeting ERK enhances the cytotoxic effect of the novel PI3K and mTOR dual inhibitor VS-5584 in preclinical models of pancreatic cancer

https://doi.org/10.18632/oncotarget.17869

Changwen Ning, Min Liang, Shuang Liu, Guan Wang, Holly Edwards, Yang Xia, Lisa Polin, Gregory Dyson, Jeffrey W. Taub, Ramzi M. Mohammad, Asfar S. Azmi, Lijing Zhao,  and Yubin Ge
44295-44311
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The impact of EpCAM expression on response to chemotherapy and clinical outcomes in patients with epithelial ovarian cancer

The impact of EpCAM expression on response to chemotherapy and clinical outcomes in patients with epithelial ovarian cancer

https://doi.org/10.18632/oncotarget.17871

Shingo Tayama, Takeshi Motohara, Dashdemberel Narantuya, Chenyan Li, Koichi Fujimoto, Isao Sakaguchi, Hironori Tashiro, Hideyuki Saya, Osamu Nagano,  and Hidetaka Katabuchi
44312-44325
Abstract  |  PDF  |  HTML  |  Order a Reprint

Increased expression of long non-coding RNA CCEPR is associated with poor prognosis and promotes tumorigenesis in urothelial bladder carcinoma

Increased expression of long non-coding RNA CCEPR is associated with poor prognosis and promotes tumorigenesis in urothelial bladder carcinoma

https://doi.org/10.18632/oncotarget.17872

Yonghao Zhan, Yifan Li, Bao Guan, Xiaoying Chen, Zhicong Chen, Anbang He, Shiming He, Yanqing Gong, Ding Peng, Yuchen Liu, Zhiming Cai, Xuesong Li,  and Liqun Zhou
44326-44334
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

EGF receptor lysosomal degradation is delayed in the cells stimulated with EGF-Quantum dot bioconjugate but earlier key events of endocytic degradative pathway are similar to that of native EGF

EGF receptor lysosomal degradation is delayed in the cells stimulated with EGF-Quantum dot bioconjugate but earlier key events of endocytic degradative pathway are similar to that of native EGF

https://doi.org/10.18632/oncotarget.17873

Anna V. Salova, Tatiana N. Belyaeva, Ekaterina A. Leontieva,  and Elena S. Kornilova
44335-44350
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impact of chronic unpredicted mild stress-induced depression on repaglinide fate via glucocorticoid signaling pathway

Impact of chronic unpredicted mild stress-induced depression on repaglinide fate via glucocorticoid signaling pathway

https://doi.org/10.18632/oncotarget.17874

Hongyan Wei, Ting Zhou, Boyu Tan, Lei Zhang, Mingming Li, Zhijun Xiao,  and Feng Xu
44351-44365
Abstract  |  PDF  |  HTML  |  Order a Reprint

New interleukin-15 superagonist (IL-15SA) significantly enhances graft-versus-tumor activity

New interleukin-15 superagonist (IL-15SA) significantly enhances graft-versus-tumor activity

https://doi.org/10.18632/oncotarget.17875

Cavan P. Bailey, Tulin Budak-Alpdogan, Christopher T. Sauter, Michelle M. Panis, Cihangir Buyukgoz, Emily K. Jeng, Hing C. Wong, Neal Flomenberg,  and Onder Alpdogan
44366-44378
Abstract  |  PDF  |  HTML  |  Order a Reprint

Histone modifications affect differential regulation of TGFβ- induced NADPH oxidase 4 (NOX4) by wild-type and mutant p53

Histone modifications affect differential regulation of TGFβ- induced NADPH oxidase 4 (NOX4) by wild-type and mutant p53

https://doi.org/10.18632/oncotarget.17892

Howard E. Boudreau, Wei Feng Ma, Agnieszka Korzeniowska, Jonathan J. Park, Medha A. Bhagwat,  and Thomas L. Leto
44379-44397
Abstract  |  PDF  |  HTML  |  Order a Reprint

Methylation regulates HEY1 expression in glioblastoma

Methylation regulates HEY1 expression in glioblastoma

https://doi.org/10.18632/oncotarget.17897

Andrew J. Tsung, Maheedhara R. Guda, Swapna Asuthkar, Collin M. Labak, Ian J. Purvis, Yining Lu, Neha Jain, Sarah E. Bach, Durbaka V.R. Prasad,  and Kiran K. Velpula
44398-44409
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dexmedetomidine alleviates lipopolysaccharide-induced lung injury in Wistar rats

Dexmedetomidine alleviates lipopolysaccharide-induced lung injury in Wistar rats

https://doi.org/10.18632/oncotarget.17899

Xuetao Yan, Xiaoli Cheng, Liwen Zhou, Xianghu He, Wenzhong Zheng,  and Hu Chen
44410-44417
Abstract  |  PDF  |  HTML  |  Order a Reprint

Characterization of tumor-associated T-lymphocyte subsets and immune checkpoint molecules in head and neck squamous cell carcinoma

Characterization of tumor-associated T-lymphocyte subsets and immune checkpoint molecules in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.17901

Axel Lechner, Hans Schlößer, Sacha I. Rothschild, Martin Thelen, Sabrina Reuter, Peter Zentis, Alexander Shimabukuro-Vornhagen, Sebastian Theurich, Kerstin Wennhold, Maria Garcia-Marquez, Lars Tharun, Alexander Quaas, Astrid Schauss, Jörg Isensee, Tim Hucho, Christian Huebbers, Michael von Bergwelt-Baildon,  and Dirk Beutner
44418-44433
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Socioeconomic status is associated with global diabetes prevalence

Socioeconomic status is associated with global diabetes prevalence

https://doi.org/10.18632/oncotarget.17902

Zhiye Xu, Dan Yu, Xueyao Yin, Fenping Zheng,  and Hong Li
44434-44439
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FGF21 functions as a sensitive biomarker of APAP-treated patients and mice

FGF21 functions as a sensitive biomarker of APAP-treated patients and mice

https://doi.org/10.18632/oncotarget.17966

Rong Li, Chao Guo, Xinmou Wu, Zhaoquan Huang,  and Jian Chen
44440-44446
Abstract  |  PDF  |  HTML  |  Order a Reprint

Vitamin D receptor activation reduces VCaP xenograft tumor growth and counteracts ERG activity despite induction of TMPRSS2:ERG

Vitamin D receptor activation reduces VCaP xenograft tumor growth and counteracts ERG activity despite induction of TMPRSS2:ERG

https://doi.org/10.18632/oncotarget.17968

Justin M. Roberts, Rebeca San Martin, D. Badrajee Piyarathna, James G. MacKrell, Guilherme V. Rocha, Jeffery A. Dodge, Cristian Coarfa, Venkatesh Krishnan, David R. Rowley,  and Nancy L. Weigel
44447-44464
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

M2 tumor-associated macrophages produce interleukin-17 to suppress oxaliplatin-induced apoptosis in hepatocellular carcinoma

M2 tumor-associated macrophages produce interleukin-17 to suppress oxaliplatin-induced apoptosis in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.17973

Bin Guo, Leilei Li, Jiapei Guo, Aidong Liu, Jinghua Wu, Haixin Wang, Jun Shi, Dequan Pang,  and Qing Cao
44465-44476
Abstract  |  PDF  |  HTML  |  Order a Reprint

Associations between APOE genotype and cerebral small-vessel disease: a longitudinal study

Associations between APOE genotype and cerebral small-vessel disease: a longitudinal study

https://doi.org/10.18632/oncotarget.17724

Xiao Luo, Yerfan Jiaerken, Xinfeng Yu, Peiyu Huang, Tiantian Qiu, Yunlu Jia, Kaicheng Li, Xiaojun Xu, Zhujing Shen, Xiaojun Guan, Jiong Zhou,  and Minming Zhang
44477-44489
Abstract  |  PDF  |  HTML  |  Order a Reprint

Interleukin-6-174G>C gene promoter polymorphism and prognosis in patients with cancer

Interleukin-6-174G>C gene promoter polymorphism and prognosis in patients with cancer

https://doi.org/10.18632/oncotarget.17771

Kan Zhai, Yong Yang, Zhi-Gang Gao,  and Jie Ding
44490-44497
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cell type-dependent HIF1 α-mediated effects of hypoxia on proliferation, migration and metastatic potential of human tumor cells

Cell type-dependent HIF1 α-mediated effects of hypoxia on proliferation, migration and metastatic potential of human tumor cells

https://doi.org/10.18632/oncotarget.17806

Enikő Tátrai, Alexandra Bartal, Alexandra Gacs, Sándor Paku, István Kenessey, Tamás Garay, Balázs Hegedűs, Eszter Molnár, Mihály T. Cserepes, Zita Hegedűs, Nóra Kucsma, Gergely Szakács,  and and József Tóvári
44498-44510
Abstract  |  PDF  |  HTML  |  Order a Reprint

Methionine restriction on oxidative stress and immune response in dss-induced colitis mice

Methionine restriction on oxidative stress and immune response in dss-induced colitis mice

https://doi.org/10.18632/oncotarget.17812

Gang Liu, Lei Yu, Jun Fang, Chien-An Andy Hu, Jie Yin, Hengjia Ni, Wenkai Ren, Veeramuthu Duraipandiyan, Shuai Chen, Naif Abdullah Al-Dhabi,  and Yulong Yin
44511-44520
Abstract  |  PDF  |  HTML  |  Order a Reprint

Actual over 10-year survival after liver resection for patients with intrahepatic cholangiocarcinoma

Actual over 10-year survival after liver resection for patients with intrahepatic cholangiocarcinoma

https://doi.org/10.18632/oncotarget.17815

Anfeng Si, Jun Li, Hongjun Xiang, Shichao Zhang, Shilei Bai, Pinghua Yang, Xiaofeng Zhang, Yong Xia, Kui Wang, Zhenlin Yan, Wan Yee Lau, Lehua Shi,  and Feng Shen
44521-44532
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

U94 of human herpesvirus 6 down-modulates Src, promotes a partial mesenchymal-to-epithelial transition and inhibits tumor cell growth, invasion and metastasis

U94 of human herpesvirus 6 down-modulates Src, promotes a partial mesenchymal-to-epithelial transition and inhibits tumor cell growth, invasion and metastasis

https://doi.org/10.18632/oncotarget.17817

Francesca Caccuri, Roberto Ronca, Andrea S. Laimbacher, Angiola Berenzi, Nathalie Steimberg, Federica Campilongo, Pietro Mazzuca, Arianna Giacomini, Giovanna Mazzoleni, Anna Benetti, Elisabetta Caselli, Marco Presta, Dario Di Luca, Cornel Fraefel,  and Arnaldo Caruso
44533-44549
Abstract  |  PDF  |  HTML  |  Order a Reprint

Rapalogs can promote cancer cell stemness in vitro in a Galectin-1 and H-ras-dependent manner

Rapalogs can promote cancer cell stemness in vitro in a Galectin-1 and H-ras-dependent manner

https://doi.org/10.18632/oncotarget.17819

Itziar M.D Posada, Benoit Lectez, Mukund Sharma, Christina Oetken-Lindholm, Laxman Yetukuri, Yong Zhou, Tero Aittokallio,  and Daniel Abankwa
44550-44566
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The bidirectional association between oral cancer and esophageal cancer: A population-based study in Taiwan over a 28-year period

The bidirectional association between oral cancer and esophageal cancer: A population-based study in Taiwan over a 28-year period

https://doi.org/10.18632/oncotarget.17818

Kuan-Der Lee, Ting-Yao Wang, Chang-Hsien Lu, Cih-En Huang,  and Min-Chi Chen
44567-44578
Abstract  |  PDF  |  HTML  |  Order a Reprint

Intravoxel incoherent motion diffusion-weighted MR imaging parameters predict pathological classification in thymic epithelial tumors

Intravoxel incoherent motion diffusion-weighted MR imaging parameters predict pathological classification in thymic epithelial tumors

https://doi.org/10.18632/oncotarget.17857

Gang-Feng Li, Shi-Jun Duan, Lin-Feng Yan, Wen Wang, Yong Jing, Wei-Qiang Yan, Qian Sun, Shu-Mei Wang, Hai-Yan Nan, Tian-Yong Xu, Dan-Dan Zheng, Yu-Chuan Hu,  and Guang-Bin Cui
44579-44592
Abstract  |  PDF  |  HTML  |  Order a Reprint

The effect of thermal dose on hyperthermia-mediated inhibition of DNA repair through homologous recombination

The effect of thermal dose on hyperthermia-mediated inhibition of DNA repair through homologous recombination

https://doi.org/10.18632/oncotarget.17861

Nathalie van den Tempel, Charlie Laffeber, Hanny Odijk, Wiggert A. van Cappellen, Gerard C. van Rhoon, Martine Franckena,  and Roland Kanaar
44593-44604
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers

The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers

https://doi.org/10.18632/oncotarget.17883

Christoffer Fagernæs Nielsen, Sander Maarten van Putten, Ida Katrine Lund, Maria Carlsén Melander, Kirstine Sandal Nørregaard, Henrik Jessen Jürgensen, Kristian Reckzeh, Kristine Rothaus Christensen, Signe Ziir Ingvarsen, Henrik Gårdsvoll, Kamilla Ellermann Jensen, Petra Hamerlik, Lars Henning Engelholm,  and Niels Behrendt
44605-44624
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dimethyl fumarate reduces the risk of mycotoxins via improving intestinal barrier and microbiota

Dimethyl fumarate reduces the risk of mycotoxins via improving intestinal barrier and microbiota

https://doi.org/10.18632/oncotarget.17886

Ning Ma, Yi Wu, Fei Xie, Kexin Du, Yuan Wang, Linxin Shi, Linbao Ji, Tianyi Liu,  and Xi Ma
44625-44638
Abstract  |  PDF  |  HTML  |  Order a Reprint

Riluzole exerts distinct antitumor effects from a metabotropic glutamate receptor 1-specific inhibitor on breast cancer cells

Riluzole exerts distinct antitumor effects from a metabotropic glutamate receptor 1-specific inhibitor on breast cancer cells

https://doi.org/10.18632/oncotarget.17961

Sonia C. Dolfi, Daniel J. Medina, Aparna Kareddula, Bhavna Paratala, Ashley Rose, Jatinder Dhami, Suzie Chen, Shridar Ganesan, Gillian Mackay, Alexei Vazquez,  and Kim M. Hirshfield
44639-44653
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Stable and high expression of Galectin-8 tightly controls metastatic progression of prostate cancer

Stable and high expression of Galectin-8 tightly controls metastatic progression of prostate cancer

https://doi.org/10.18632/oncotarget.17963

Lucas Daniel Gentilini, Felipe Martín Jaworski, Carolina Tiraboschi, Ignacio González Pérez, Monica Lidia Kotler, Anne Chauchereau, Diego Jose Laderach,  and Daniel Compagno
44654-44668
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

BRSK2 induced by nutrient deprivation promotes Akt activity in pancreatic cancer via downregulation of mTOR activity

BRSK2 induced by nutrient deprivation promotes Akt activity in pancreatic cancer via downregulation of mTOR activity

https://doi.org/10.18632/oncotarget.17965

Hexige Saiyin, Ning Na, Xu Han, Yuan Fang, Yanhua Wu, Wenhui Lou,  and Xianmei Yang
44669-44681
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ginkgolide K attenuates neuronal injury after ischemic stroke by inhibiting mitochondrial fission and GSK-3β-dependent increases in mitochondrial membrane permeability

Ginkgolide K attenuates neuronal injury after ischemic stroke by inhibiting mitochondrial fission and GSK-3β-dependent increases in mitochondrial membrane permeability

https://doi.org/10.18632/oncotarget.17967

Xu Zhou, Hui-Ying Wang, Bin Wu, Cai-Yi Cheng, Wei Xiao, Zhen-Zhong Wang, Yu-Yu Yang, Ping Li,  and Hua Yang
44682-44693
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FOXP3 inhibits cancer stem cell self-renewal via transcriptional repression of COX2 in colorectal cancer cells

FOXP3 inhibits cancer stem cell self-renewal via transcriptional repression of COX2 in colorectal cancer cells

https://doi.org/10.18632/oncotarget.17974

Shuo Liu, Cun Zhang, Kou Zhang, Yuan Gao, Zhaowei Wang, Xiaoju Li, Guang Cheng, Shuning Wang, Xiaochang Xue, Weina Li, Wei Zhang, Yingqi Zhang, Xianghui Xing, Meng Li,  and Qiang Hao
44694-44704
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genome-wide methylome and chromatin interactome identify abnormal enhancer to be risk factor of breast cancer

Genome-wide methylome and chromatin interactome identify abnormal enhancer to be risk factor of breast cancer

https://doi.org/10.18632/oncotarget.18348

Yuan Wang, Da-Peng Hao, Jing-Jing Li, Li Wang,  and Li-Jun Di
44705-44719
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Antagonistic effects of lycopene on cadmium-induced hippocampal dysfunctions in autophagy, calcium homeostatis and redox

Antagonistic effects of lycopene on cadmium-induced hippocampal dysfunctions in autophagy, calcium homeostatis and redox

https://doi.org/10.18632/oncotarget.18249

Fenghua Zhang, Suping Xing,  and Zongpeng Li
44720-44731
Abstract  |  PDF  |  HTML  |  Order a Reprint

Catecholamines facilitate VEGF-dependent angiogenesis via β2-adrenoceptor-induced Epac1 and PKA activation

Catecholamines facilitate VEGF-dependent angiogenesis via β2-adrenoceptor-induced Epac1 and PKA activation

https://doi.org/10.18632/oncotarget.17267

Jaspal Garg, Yu-Xi Feng, Sepp R. Jansen, Julian Friedrich, Frank Lezoualc'h, Martina Schmidt,  and Thomas Wieland
44732-44748
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dynamic changes in clonal cytogenetic architecture during progression of chronic lymphocytic leukemia in patients and patient-derived murine xenografts

Dynamic changes in clonal cytogenetic architecture during progression of chronic lymphocytic leukemia in patients and patient-derived murine xenografts

https://doi.org/10.18632/oncotarget.17432

Nicholas J. Davies, Marwan Kwok, Clive Gould, Ceri E. Oldreive, Jingwen Mao, Helen Parry, Edward Smith, Angelo Agathanggelou, Guy Pratt, Alexander Malcolm R. Taylor, Paul Moss, Mike Griffiths,  and Tatjana Stankovic
44749-44760
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Meta-Analysis

Human 8-oxoguanine DNA glycosylase gene polymorphism (Ser326Cys) and cancer risk: updated meta-analysis

Human 8-oxoguanine DNA glycosylase gene polymorphism (Ser326Cys) and cancer risk: updated meta-analysis

https://doi.org/10.18632/oncotarget.16226

Sang Wook Kang, Su Kang Kim, Hae Jeong Park, Joo-Ho Chung,  and Ju Yeon Ban
44761-44775
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Legume intake and risk of prostate cancer: a meta-analysis of prospective cohort studies

Legume intake and risk of prostate cancer: a meta-analysis of prospective cohort studies

https://doi.org/10.18632/oncotarget.16794

Jie Li,  and Qi-Qi Mao
44776-44784
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Altered brain structural networks in attention deficit/hyperactivity disorder children revealed by cortical thickness

Altered brain structural networks in attention deficit/hyperactivity disorder children revealed by cortical thickness

https://doi.org/10.18632/oncotarget.14734

Tian Liu, Yanni Chen, Chenxi Li, Youjun Li,  and Jue Wang
44785-44799
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hormonal therapy followed by chemotherapy or the reverse sequence as first-line treatment of hormone-responsive, human epidermal growth factor receptor-2 negative metastatic breast cancer patients: results of an observational study

Hormonal therapy followed by chemotherapy or the reverse sequence as first-line treatment of hormone-responsive, human epidermal growth factor receptor-2 negative metastatic breast cancer patients: results of an observational study

https://doi.org/10.18632/oncotarget.14735

Claudia Bighin, Beatrice Dozin, Francesca Poggio, Marcello Ceppi, Paolo Bruzzi, Alessia D’Alonzo, Alessia Levaggi, Sara Giraudi, Matteo Lambertini, Loredana Miglietta, Marina Vaglica, Vincenzo Fontana, Giuseppina Iacono, Paolo Pronzato,  and Lucia Del Mastro
44800-44810
Abstract  |  PDF  |  HTML  |  Order a Reprint

Safety and efficacy of canaloplasty versus trabeculectomy in treatment of glaucoma

Safety and efficacy of canaloplasty versus trabeculectomy in treatment of glaucoma

https://doi.org/10.18632/oncotarget.14757

Haifeng Liu, Haitao Zhang, Yanhua Li,  and Han Yu
44811-44818
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

After microvascular decompression to treat trigeminal neuralgia, both immediate pain relief and recurrence rates are higher in patients with arterial compression than with venous compression

After microvascular decompression to treat trigeminal neuralgia, both immediate pain relief and recurrence rates are higher in patients with arterial compression than with venous compression

https://doi.org/10.18632/oncotarget.14765

Lei Shi, Xiaoyan Gu, Guan Sun, Jun Guo, Xin Lin, Shuguang Zhang,  and Chunfa Qian
44819-44823
Abstract  |  PDF  |  HTML  |  Order a Reprint

Predictive value of hematological markers of systemic inflammation for managing cervical cancer

Predictive value of hematological markers of systemic inflammation for managing cervical cancer

https://doi.org/10.18632/oncotarget.14827

Lin Wang, Jing Jia, Lu Lin, Junying Guo, Xingming Ye, Xiongwei Zheng,  and Ying Chen
44824-44832
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Conversion to mammalian target of rapamycin inhibitors in kidney transplant recipients with de novo cancers

Conversion to mammalian target of rapamycin inhibitors in kidney transplant recipients with de novo cancers

https://doi.org/10.18632/oncotarget.14908

Chi Yuen Cheung, Maggie Kam Man Ma, Wai Leung Chak, Ka Foon Chau,  and Sydney Chi Wai Tang
44833-44841
Abstract  |  PDF  |  HTML  |  Order a Reprint

Phase III randomized trial of preoperative concurrent chemoradiotherapy versus preoperative radiotherapy for patients with locally advanced head and neck squamous cell carcinoma

Phase III randomized trial of preoperative concurrent chemoradiotherapy versus preoperative radiotherapy for patients with locally advanced head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.15107

Junlin Yi, Xiaodong Huang, Zhengang Xu, Shaoyan Liu, Xiaolei Wang, Xiaohui He, Dehong Luo, Jingwei Luo, Jianping Xiao, Shiping Zhang, Kai Wang, Yuan Qu, Yuan Tang, Weixin Liu, Guozhen Xu, Li Gao,  and Dian Wang
44842-44850
Abstract  |  PDF  |  HTML  |  Order a Reprint

Young breast cancer patients who develop distant metastasis after surgery have better survival outcomes compared with elderly counterparts

Young breast cancer patients who develop distant metastasis after surgery have better survival outcomes compared with elderly counterparts

https://doi.org/10.18632/oncotarget.15268

Jingjing Wang, Jiayu Wang, Qing Li, Pin Zhang, Peng Yuan, Fei Ma, Yang Luo, Ruigang Cai, Ying Fan, Shanshan Chen, Qiao Li,  and Binghe Xu
44851-44859
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Endoscopic therapy for patients with pancreaticobiliary maljunction: a follow-up study

Endoscopic therapy for patients with pancreaticobiliary maljunction: a follow-up study

https://doi.org/10.18632/oncotarget.16228

Zheng Jin, Li-Ke Bie, Yan-Ping Tang, Liang Ge, Si-Si Shen, Bin Xu, Tao Li,  and Biao Gong
44860-44869
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The lymph node ratio as an independent prognostic factor for node-positive triple-negative breast cancer

The lymph node ratio as an independent prognostic factor for node-positive triple-negative breast cancer

https://doi.org/10.18632/oncotarget.17413

Min He, Jia-Xin Zhang, Yi-Zhou Jiang, Ying-Le Chen, Hai-Yuan Yang, Li-Chen Tang, Zhi-Ming Shao,  and Gen-Hong Di
44870-44880
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reviews

Diabetes mellitus and the risk of gastric cancer: a meta-analysis of cohort studies

Diabetes mellitus and the risk of gastric cancer: a meta-analysis of cohort studies

https://doi.org/10.18632/oncotarget.16487

Zhi-Feng Miao, Hao Xu, Ying-Ying Xu, Zhen-Ning Wang, Ting-Ting Zhao, Yong-Xi Song,  and Hui-Mian Xu
44881-44892
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The clinical role of microRNA-21 as a promising biomarker in the diagnosis and prognosis of colorectal cancer: a systematic review and meta-analysis

The clinical role of microRNA-21 as a promising biomarker in the diagnosis and prognosis of colorectal cancer: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.16488

Qiliang Peng, Xueli Zhang, Ming Min, Li Zou, Peipei Shen,  and Yaqun Zhu
44893-44909
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association between HIF1A rs11549465 polymorphism and risk of prostate cancer: a meta-analysis

Association between HIF1A rs11549465 polymorphism and risk of prostate cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.16489

Xiao-Dong Li, Hao Zi, Cheng Fang,  and Xian-Tao Zeng
44910-44916
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The dark side of SOX2: cancer - a comprehensive overview

The dark side of SOX2: cancer - a comprehensive overview

https://doi.org/10.18632/oncotarget.16570

Erin L. Wuebben,  and Angie Rizzino
44917-44943
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Dose dependent effects of cadmium on tumor angiogenesis

Dose dependent effects of cadmium on tumor angiogenesis

https://doi.org/10.18632/oncotarget.16572

Tianshu Wei, Jin Jia, Youichiro Wada, Carolyn M. Kapron,  and Ju Liu
44944-44959
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Mechanisms of PD-1/PD-L1 expression and prognostic relevance in non-Hodgkin lymphoma: a summary of immunohistochemical studies

Mechanisms of PD-1/PD-L1 expression and prognostic relevance in non-Hodgkin lymphoma: a summary of immunohistochemical studies

https://doi.org/10.18632/oncotarget.16680

Pauline Gravelle, Barbara Burroni, Sarah Péricart, Cédric Rossi, Christine Bezombes, Marie Tosolini, Diane Damotte, Pierre Brousset, Jean-Jacques Fournié,  and Camille Laurent
44960-44975
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Thalidomide combined with transcatheter artierial chemoembolzation for primary hepatocellular carcinoma: a systematic review and meta-analysis

Thalidomide combined with transcatheter artierial chemoembolzation for primary hepatocellular carcinoma: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.16689

De-Dong Cao, Hui-Lin Xu, Liang Liu, Yong-Fa Zheng, Si-Fa Gao, Xi-Ming Xu,  and Wei Ge
44976-44993
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Meta-analysis of the association between variants in MAPT and neurodegenerative diseases

Meta-analysis of the association between variants in MAPT and neurodegenerative diseases

https://doi.org/10.18632/oncotarget.16690

Cheng-Cheng Zhang, Jun-Xia Zhu, Yu Wan, Lin Tan, Hui-Fu Wang, Jin-Tai Yu,  and Lan Tan
44994-45007
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Physical activity and telomere length: Impact of aging and potential mechanisms of action

Physical activity and telomere length: Impact of aging and potential mechanisms of action

https://doi.org/10.18632/oncotarget.16726

Nicole C. Arsenis, Tongjian You, Elisa F. Ogawa, Grant M. Tinsley,  and Li Zuo
45008-45019
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Association between MMP2-1306 C/T polymorphism and prostate cancer susceptibility: a meta-analysis based on 3906 subjects

Association between MMP2-1306 C/T polymorphism and prostate cancer susceptibility: a meta-analysis based on 3906 subjects

https://doi.org/10.18632/oncotarget.16972

Kaiping Zhang, Xianguo Chen, Jun Zhou, Cheng Yang, Meng Zhang, Min Chao, Li Zhang,  and Chaozhao Liang
45020-45029
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Corrections

Correction: Physiological characterization of a novel PPAR pan agonist, 2-(4-(5,6-methylenedioxybenzo[d]thiazol-2-yl)-2-methylphenoxy)-2-methylpropanoic acid (MHY2013)

Correction: Physiological characterization of a novel PPAR pan agonist, 2-(4-(5,6-methylenedioxybenzo[d]thiazol-2-yl)-2-methylphenoxy)-2-methylpropanoic acid (MHY2013)

https://doi.org/10.18632/oncotarget.18922

Hye Jin An, Bonggi Lee, Dae Hyun Kim, Eun Kyeong Lee, Ki Wung Chung, Min Hi Park, Hyoung Oh Jeong, Sung Min Kim, Kyoung Mi Moon, Ye Ra Kim, Seong Jin Kim, Hwi Young Yun, Pusoon Chun, Byung Pal Yu, Hyung Ryong Moon,  and Hae Young Chung
45030-45030
Correction  |  PDF

Correction: High-level expression of P21-Cdc/Rac-activated kinase 7 is closely related to metastatic potential and poor prognosis of colon carcinoma

Correction: High-level expression of P21-Cdc/Rac-activated kinase 7 is closely related to metastatic potential and poor prognosis of colon carcinoma

https://doi.org/10.18632/oncotarget.18923

Chao Li, Jian Chen, Yupeng Wang, Guohe Song, Chao Xiao, Dongwang Yan, Lin Zhong, Xing Sun, Xiaoliang Wang, Fudong Yu, Yang Yu, Huamei Tang,  and Zhihai Peng
45031-45031
Correction  |  PDF


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