Oncotarget

Vol 8, No 26

June 27, 2017

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About The Cover

The cover for issue 26 of Oncotarget features Figure 1B, "Tumor architecture obtained through GQI tractography in rats injected with F98 glioblastoma cells (N = 3)," from Taylor, et al.

Table of Contents

News

The tuberous sclerosis complex gets fatter

The tuberous sclerosis complex gets fatter

https://doi.org/10.18632/oncotarget.18436

Prashanth Gokare,  and Wafik S. El-Deiry
41780-41781
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New perspectives for colorectal cancer

New perspectives for colorectal cancer

https://doi.org/10.18632/oncotarget.18448

Alberto Puccini,  and Heinz-Josef Lenz
41782-41783
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Mutational cascades in cancer

Mutational cascades in cancer

https://doi.org/10.18632/oncotarget.18481

Clement Richard Boland,  and Matthew B. Yurgelun
41784-41785
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Editorial

Intermittent hypoxia produces Alzheimer disease?

Intermittent hypoxia produces Alzheimer disease?

https://doi.org/10.18632/oncotarget.18214

Sosuke Yagishita,  and Akira Hirasawa
41786-41787
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ASICs may affect GABAergic synapses

ASICs may affect GABAergic synapses

https://doi.org/10.18632/oncotarget.18247

Maksim Storozhuk,  and Oleg Krishtal
41788-41789
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Editorial: Autophagy and Cell Death

Die later with ESCRT!

Die later with ESCRT!

https://doi.org/10.18632/oncotarget.17903

Wulf Tonnus, Florian Gembardt, Christian Hugo,  and Andreas Linkermann
41790-41791
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Priority Research Perspective

Tumor diversity and evolution revealed through RADseq

Tumor diversity and evolution revealed through RADseq

https://doi.org/10.18632/oncotarget.18355

Elizabeth B. Perry, Alvin Makohon-Moore, Caihong Zheng, Charles K. Kaufman, Jun Cai, Christine A. Iacobuzio-Donahue,  and Richard M. White
41792-41805
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Priority Research Papers

A feasibility study of returning clinically actionable somatic genomic alterations identified in a research laboratory

A feasibility study of returning clinically actionable somatic genomic alterations identified in a research laboratory

https://doi.org/10.18632/oncotarget.16018

Natalia Paez Arango, Lauren Brusco, Kenna R. Mills Shaw, Ken Chen, Agda Karina Eterovic, Vijaykumar Holla, Amber Johnson, Beate Litzenburger, Yekaterina B. Khotskaya, Nora Sanchez, Ann Bailey, Xiaofeng Zheng, Chacha Horombe, Scott Kopetz, Carol J. Farhangfar, Mark Routbort, Russell Broaddus, Elmer V. Bernstam, John Mendelsohn, Gordon B. Mills,  and Funda Meric-Bernstam
41806-41814
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Association between tumor architecture derived from generalized Q-space MRI and survival in glioblastoma

Association between tumor architecture derived from generalized Q-space MRI and survival in glioblastoma

https://doi.org/10.18632/oncotarget.16296

Erik N. Taylor, Yao Ding, Shan Zhu, Eric Cheah, Phillip Alexander, Leon Lin, George E. Aninwene II, Matthew P. Hoffman, Anita Mahajan, Abdallah S.R. Mohamed, Nathan McDannold, Clifton D. Fuller, Clark C. Chen,  and Richard J. Gilbert
41815-41826
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Selective inhibition of matrix metalloproteinase-2 in the multiple myeloma-bone microenvironment

Selective inhibition of matrix metalloproteinase-2 in the multiple myeloma-bone microenvironment

https://doi.org/10.18632/oncotarget.18103

Gemma Shay, Marilena Tauro, Fulvio Loiodice, Paolo Tortorella, Daniel Sullivan, Lori Hazlehurst,  and Conor C. Lynch
41827-41840
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Cblb-deficient T cells are less susceptible to PD-L1-mediated inhibition

Cblb-deficient T cells are less susceptible to PD-L1-mediated inhibition

https://doi.org/10.18632/oncotarget.18360

Sebastian Peer, Gottfried Baier,  and Thomas Gruber
41841-41853
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Research Papers: Immunology

Chromatin state dynamics during NK cell activation

Chromatin state dynamics during NK cell activation

https://doi.org/10.18632/oncotarget.16688

Yang Li, Jin Wang, Jie Yin, Xinhua Liu, Minghang Yu, Ting Li, Han Yan,  and Xi Wang
41854-41865
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers

Human microRNA expression in sporadic and FAP-associated desmoid tumors and correlation with beta-catenin mutations

Human microRNA expression in sporadic and FAP-associated desmoid tumors and correlation with beta-catenin mutations

https://doi.org/10.18632/oncotarget.16383

Aldo Cavallini, Maria Teresa Rotelli, Catia Lippolis, Domenico Piscitelli, Rosa Digennaro, Claudia Covelli, Nicola Carella, Matteo Accetturo,  and Donato Francesco Altomare
41866-41875
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Oncogenic STAT5 signaling promotes oxidative stress in chronic myeloid leukemia cells by repressing antioxidant defenses

Oncogenic STAT5 signaling promotes oxidative stress in chronic myeloid leukemia cells by repressing antioxidant defenses

https://doi.org/10.18632/oncotarget.11480

Jerome Bourgeais, Nicole Ishac, Magdalena Medrzycki, Marie Brachet-Botineau, Laura Desbourdes, Valerie Gouilleux-Gruart, Emmanuel Pecnard, Florence Rouleux-Bonnin, Emmanuel Gyan, Jorge Domenech, Frederic Mazurier, Richard Moriggl, Kevin D. Bunting, Olivier Herault,  and Fabrice Gouilleux
41876-41889
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epigenome-wide association study in hepatocellular carcinoma: Identification of stochastic epigenetic mutations through an innovative statistical approach

Epigenome-wide association study in hepatocellular carcinoma: Identification of stochastic epigenetic mutations through an innovative statistical approach

https://doi.org/10.18632/oncotarget.17462

Davide Gentilini, Stefania Scala, Germano Gaudenzi, Paolo Garagnani, Miriam Capri, Matteo Cescon, Gian Luca Grazi, Maria Giulia Bacalini, Serena Pisoni, Alessandra Dicitore, Luisa Circelli, Sara Santagata, Francesco Izzo, Anna Maria Di Blasio, Luca Persani, Claudio Franceschi,  and Giovanni Vitale
41890-41902
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Tristetraprolin inhibits mitochondrial function through suppression of α-Synuclein expression in cancer cells

Tristetraprolin inhibits mitochondrial function through suppression of α-Synuclein expression in cancer cells

https://doi.org/10.18632/oncotarget.16706

Mai-Tram Vo, Seong Hee Choi, Ji-Heon Lee, Chung Hwan Hong, Jong Soo Kim, Unn Hwa Lee, Hyung-Min Chung, Byung Ju Lee, Jeong Woo Park,  and Wha Ja Cho
41903-41920
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MiR-106b inhibitors sensitize TRAIL-induced apoptosis in hepatocellular carcinoma through increase of death receptor 4

MiR-106b inhibitors sensitize TRAIL-induced apoptosis in hepatocellular carcinoma through increase of death receptor 4

https://doi.org/10.18632/oncotarget.16707

Changlong Xu, Liang Shi, Weilai Chen, Peipei Fang, Jie Li, Lingxiang Jin, Zhenzhen Pan,  and Chenwei Pan
41921-41931
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Non-invasive assessment of murine PD-L1 levels in syngeneic tumor models by nuclear imaging with nanobody tracers

Non-invasive assessment of murine PD-L1 levels in syngeneic tumor models by nuclear imaging with nanobody tracers

https://doi.org/10.18632/oncotarget.16708

Katrijn Broos, Marleen Keyaerts, Quentin Lecocq, Dries Renmans, Tham Nguyen, David Escors, Adrian Liston, Geert Raes, Karine Breckpot,  and Nick Devoogdt
41932-41946
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Hypoxia-induced PLOD2 promotes proliferation, migration and invasion via PI3K/Akt signaling in glioma

Hypoxia-induced PLOD2 promotes proliferation, migration and invasion via PI3K/Akt signaling in glioma

https://doi.org/10.18632/oncotarget.16710

Ye Song, Shihao Zheng, Jizhou Wang, Hao Long, Luxiong Fang, Gang Wang, Zhiyong Li, Tianshi Que, Yi Liu, Yilei Li, Xi’an Zhang, Weiyi Fang,  and Songtao Qi
41947-41962
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A short synthetic peptide fragment of human C2ORF40 has therapeutic potential in breast cancer

A short synthetic peptide fragment of human C2ORF40 has therapeutic potential in breast cancer

https://doi.org/10.18632/oncotarget.16713

Chaoyang Lin, Pengju Zhang, Anli Jiang, Jian-Hua Mao,  and Guangwei Wei
41963-41974
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Friend leukemia virus integration 1 promotes tumorigenesis of small cell lung cancer cells by activating the miR-17-92 pathway

Friend leukemia virus integration 1 promotes tumorigenesis of small cell lung cancer cells by activating the miR-17-92 pathway

https://doi.org/10.18632/oncotarget.16715

Lingyu Li, Wei Song, Xu Yan, Ailing Li, Xiaoying Zhang, Wei Li, Xue Wen, Lei Zhou, Dehai Yu, Ji-Fan Hu,  and Jiuwei Cui
41975-41987
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pterostilbene inhibits inflammation and ROS production in chondrocytes by activating Nrf2 pathway

Pterostilbene inhibits inflammation and ROS production in chondrocytes by activating Nrf2 pathway

https://doi.org/10.18632/oncotarget.16716

En-Xing Xue, Jian-Ping Lin, Yu Zhang, Sun-Ren Sheng, Hai-Xiao Liu, Yu-Long Zhou,  and Hui Xu
41988-42000
Abstract  |  PDF  |  HTML  |  Order a Reprint

6-Shogaol attenuates LPS-induced inflammation in BV2 microglia cells by activating PPAR-γ

6-Shogaol attenuates LPS-induced inflammation in BV2 microglia cells by activating PPAR-γ

https://doi.org/10.18632/oncotarget.16719

Qinghe Han, Qinghai Yuan, Xiaolin Meng, Junyuan Huo, Yuxin Bao,  and Guanghong Xie
42001-42006
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Decreased expression of the NKG2D ligand ULBP4 may be an indicator of poor prognosis in patients with nasopharyngeal carcinoma

Decreased expression of the NKG2D ligand ULBP4 may be an indicator of poor prognosis in patients with nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.14917

Yuanji Xu, Lin Zhou, Jingfeng Zong, Yunbin Ye, Gang Chen, Yanping Chen, Xuehong Liao, Qiaojuan Guo, Sufang Qiu, Shaojun Lin, Honglin Chen,  and Jianji Pan
42007-42019
Abstract  |  PDF  |  HTML  |  Order a Reprint

Compared planning dosimetry of TOMO, VMAT and IMRT in rectal cancer with different simulated positions

Compared planning dosimetry of TOMO, VMAT and IMRT in rectal cancer with different simulated positions

https://doi.org/10.18632/oncotarget.14923

Jang-Chun Lin, Jo-Ting Tsai, Li-Jhen Chen, Ming-Hsien Li,  and Wei-Hsiu Liu
42020-42029
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Modeling the differential phenotypes of spinal muscular atrophy with high-yield generation of motor neurons from human induced pluripotent stem cells

Modeling the differential phenotypes of spinal muscular atrophy with high-yield generation of motor neurons from human induced pluripotent stem cells

https://doi.org/10.18632/oncotarget.14925

Xiang Lin, Jin-Jing Li, Wen-Jing Qian, Qi-Jie Zhang, Zhong-Feng Wang, Ying-Qian Lu, En-Lin Dong, Jin He, Ning Wang, Li-Xiang Ma,  and Wan-Jin Chen
42030-42042
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumor suppressor miR-1 inhibits tumor growth and metastasis by simultaneously targeting multiple genes

Tumor suppressor miR-1 inhibits tumor growth and metastasis by simultaneously targeting multiple genes

https://doi.org/10.18632/oncotarget.14927

Cuilian Liu, Song Zhang, Qizhi Wang,  and Xiaobo Zhang
42043-42060
Abstract  |  PDF  |  HTML  |  Order a Reprint

LncRNAs as an intermediate in HPV16 promoting myeloid-derived suppressor cell recruitment of head and neck squamous cell carcinoma

LncRNAs as an intermediate in HPV16 promoting myeloid-derived suppressor cell recruitment of head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.14939

Xiangrui Ma, Surui Sheng, Jingbiao Wu, Yaping Jiang, Xiaolei Gao, Xiao Cen, Jiashun Wu, Shasha Wang, Yajie Tang, Yaling Tang,  and Xinhua Liang
42061-42075
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sulfatinib, a novel kinase inhibitor, in patients with advanced solid tumors: results from a phase I study

Sulfatinib, a novel kinase inhibitor, in patients with advanced solid tumors: results from a phase I study

https://doi.org/10.18632/oncotarget.14942

Jian Ming Xu, Yan Wang, Yu Ling Chen, Ru Jia, Jie Li, Ji Fang Gong, Jing Li, Chuan Qi, Ye Hua, Cui Rong Tan, Jian Wang, Ke Li, Yang Sai, Feng Zhou, Yong Xin Ren, Wei Guo Qing, Hong Jia, Wei Guo Su,  and Lin Shen
42076-42086
Abstract  |  PDF  |  HTML  |  Order a Reprint

Long non-coding RNA-CRNDE: a novel regulator of tumor growth and angiogenesis in hepatoblastoma

Long non-coding RNA-CRNDE: a novel regulator of tumor growth and angiogenesis in hepatoblastoma

https://doi.org/10.18632/oncotarget.14992

Rui Dong, Xiang-Qi Liu, Bin-Bin Zhang, Bai-Hui Liu, Shan Zheng,  and Kui-Ran Dong
42087-42097
Abstract  |  PDF  |  HTML  |  Order a Reprint

Local delivery of HMGB1 in gelatin sponge scaffolds combined with mesenchymal stem cell sheets to accelerate fracture healing

Local delivery of HMGB1 in gelatin sponge scaffolds combined with mesenchymal stem cell sheets to accelerate fracture healing

https://doi.org/10.18632/oncotarget.16887

Deting Xue, Wei Zhang, Erman Chen, Xiang Gao, Ling Liu, Chenyi Ye, Yanbin Tan, Zhijun Pan,  and Hang Li
42098-42115
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ERCC6L, a DNA helicase, is involved in cell proliferation and associated with survival and progress in breast and kidney cancers

ERCC6L, a DNA helicase, is involved in cell proliferation and associated with survival and progress in breast and kidney cancers

https://doi.org/10.18632/oncotarget.14998

Shao-Yan Pu, Qin Yu, Huan Wu, Jian-Jun Jiang, Xiao-Qiong Chen, Yong-Han He,  and Qing-Peng Kong
42116-42124
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comparative analysis of microRNA expression profiles between A549, A549/DDP and their respective exosomes

Comparative analysis of microRNA expression profiles between A549, A549/DDP and their respective exosomes

https://doi.org/10.18632/oncotarget.15009

Xiaobing Qin, Shaorong Yu, Xiaoyue Xu, Bo Shen,  and Jifeng Feng
42125-42135
Abstract  |  PDF  |  HTML  |  Order a Reprint

Actinidia chinensis Planch root extract inhibits cholesterol metabolism in hepatocellular carcinoma through upregulation of PCSK9

Actinidia chinensis Planch root extract inhibits cholesterol metabolism in hepatocellular carcinoma through upregulation of PCSK9

https://doi.org/10.18632/oncotarget.15010

Mingyan He, Jiayun Hou, Lingyan Wang, Minghuan Zheng, Tingting Fang, Xiangdong Wang,  and Jinglin Xia
42136-42148
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Plasma cytokine and angiogenic factors associated with prognosis and therapeutic response to sunitinib vs everolimus in advanced non-clear cell renal cell carcinoma

Plasma cytokine and angiogenic factors associated with prognosis and therapeutic response to sunitinib vs everolimus in advanced non-clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.15011

Pavlos Msaouel, Amado J. Zurita, Shixia Huang, Eric Jonasch,  and Nizar M. Tannir
42149-42158
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression of karyopherin-α2 in cholangiocarcinoma correlates with poor prognosis and gemcitabine sensitivity via nuclear translocation of DNA repair proteins

Overexpression of karyopherin-α2 in cholangiocarcinoma correlates with poor prognosis and gemcitabine sensitivity via nuclear translocation of DNA repair proteins

https://doi.org/10.18632/oncotarget.15020

Mariko Tsukagoshi, Kenichiro Araki, Takehiko Yokobori, Bolag Altan, Hideki Suzuki, Norio Kubo, Akira Watanabe, Norihiro Ishii, Yasuo Hosouchi, Masahiko Nishiyama, Ken Shirabe,  and Hiroyuki Kuwano
42159-42172
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circulating microRNA-422a is associated with lymphatic metastasis in lung cancer

Circulating microRNA-422a is associated with lymphatic metastasis in lung cancer

https://doi.org/10.18632/oncotarget.15025

Li-Na Wu, Bo Hu, Bing-Tian Zhao, Yi-Nan Liu, Yue Yang, Li-Jian Zhang,  and Jin-Feng Chen
42173-42188
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value of follistatin-like 3 in human invasive breast cancer

Prognostic value of follistatin-like 3 in human invasive breast cancer

https://doi.org/10.18632/oncotarget.15026

Henrique L. Couto, Marcelo A. Buzelin, Nivaldo H. Toppa, Enrrico Bloise, Alberto J. Wainstein,  and Fernando M. Reis
42189-42197
Abstract  |  PDF  |  HTML  |  Order a Reprint

Molecular profiling of metastatic colorectal tumors using next-generation sequencing: a single-institution experience

Molecular profiling of metastatic colorectal tumors using next-generation sequencing: a single-institution experience

https://doi.org/10.18632/oncotarget.15030

Jun Gong, May Cho, Marvin Sy, Ravi Salgia,  and Marwan Fakih
42198-42213
Abstract  |  PDF  |  HTML  |  Order a Reprint

Comprehensive analysis of PD-L1 expression in glioblastoma multiforme

Comprehensive analysis of PD-L1 expression in glioblastoma multiforme

https://doi.org/10.18632/oncotarget.15031

Dieter Henrik Heiland, Gerrit Haaker, Daniel Delev, Bianca Mercas, Waseem Masalha, Sabrina Heynckes, Annette Gabelein, Dietmar Pfeifer, Maria Stella Carro, Astrid Weyerbrock, Marco Prinz,  and Oliver Schnell
42214-42225
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GSPE reduces lead-induced oxidative stress by activating the Nrf2 pathway and suppressing miR153 and GSK-3β in rat kidney

GSPE reduces lead-induced oxidative stress by activating the Nrf2 pathway and suppressing miR153 and GSK-3β in rat kidney

https://doi.org/10.18632/oncotarget.15033

Biying Liu, Haili Zhang, Xiao Tan, Daqian Yang, Zhanjun Lv, Huijie Jiang, Jingjing Lu, Ruiqi Baiyun,  and Zhigang Zhang
42226-42237
Abstract  |  PDF  |  HTML  |  Order a Reprint

Lectin from Sambucus sieboldiana abrogates the anoikis resistance of colon cancer cells conferred by N-acetylglucosaminyltransferase V during hematogenous metastasis

Lectin from Sambucus sieboldiana abrogates the anoikis resistance of colon cancer cells conferred by N-acetylglucosaminyltransferase V during hematogenous metastasis

https://doi.org/10.18632/oncotarget.15034

Kyoung Jin Song, Seong Kook Jeon, Su Bin Moon, Jin Suk Park, Jang Seong Kim, Jeongkwon Kim, Sumin Kim, Hyun Joo An, Jeong-Heon Ko,  and Yong-Sam Kim
42238-42251
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overwhelming rapid metabolic and structural response to apatinib in radioiodine refractory differentiated thyroid cancer

Overwhelming rapid metabolic and structural response to apatinib in radioiodine refractory differentiated thyroid cancer

https://doi.org/10.18632/oncotarget.15036

Yansong Lin, Chen Wang, Wen Gao, Ruixue Cui,  and Jun Liang
42252-42261
Abstract  |  PDF  |  HTML  |  Order a Reprint

Malignant ascites-derived exosomes promote proliferation and induce carcinoma-associated fibroblasts transition in peritoneal mesothelial cells

Malignant ascites-derived exosomes promote proliferation and induce carcinoma-associated fibroblasts transition in peritoneal mesothelial cells

https://doi.org/10.18632/oncotarget.15040

Mingtian Wei, Tinghan Yang, Xiangzheng Chen, Yangping Wu, Xiangbing Deng, Wanbin He, Jinliang Yang,  and Ziqiang Wang
42262-42271
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Beluga whale pVHL enhances HIF-2α activity via inducing HIF-2α proteasomal degradation under hypoxia

Beluga whale pVHL enhances HIF-2α activity via inducing HIF-2α proteasomal degradation under hypoxia

https://doi.org/10.18632/oncotarget.15038

Jianling Bi, Bo Hu, Jing Wang, Xing Liu, Jinsong Zheng, Ding Wang,  and Wuhan Xiao
42272-42287
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Upregulated WEE1 protects endothelial cells of colorectal cancer liver metastases

Upregulated WEE1 protects endothelial cells of colorectal cancer liver metastases

https://doi.org/10.18632/oncotarget.15039

Peter J. Webster, Anna T. Littlejohns, Hannah J. Gaunt, Richard S. Young, Baptiste Rode, Judith E. Ritchie, Lucy F. Stead, Sally Harrison, Alastair Droop, Heather L. Martin, Darren C. Tomlinson, Adam J. Hyman, Hollie L. Appleby, Sally Boxall, Alexander F. Bruns, Jing Li, K.Raj Prasad, J.Peter A. Lodge, Dermot A. Burke,  and David J. Beech
42288-42299
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Urokinase plasminogen activator secreted by cancer-associated fibroblasts induces tumor progression via PI3K/AKT and ERK signaling in esophageal squamous cell carcinoma

Urokinase plasminogen activator secreted by cancer-associated fibroblasts induces tumor progression via PI3K/AKT and ERK signaling in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.15857

Baoqing Tian, Xiaojia Chen, Huihua Zhang, Xiaoyan Li, Jiakang Wang, Wei Han, Li-Yi Zhang, Li Fu, Yan Li, Changjun Nie, Ying Zhao, Xuan Tan, Hailong Wang, Xin-Yuan Guan,  and An Hong
42300-42313
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hydrogen-rich saline attenuates spinal cord hemisection-induced testicular injury in rats

Hydrogen-rich saline attenuates spinal cord hemisection-induced testicular injury in rats

https://doi.org/10.18632/oncotarget.15876

Li Ge, Li-Hua Wei, Chang-Qing Du, Guo-Hua Song, Ya-Zhuo Xue, Hao-Shen Shi, Ming Yang, Xin-Xin Yin, Run-Ting Li, Xue-er Wang, Zhen Wang,  and Wen-Gang Song
42314-42331
Abstract  |  PDF  |  HTML  |  Order a Reprint

Circulating uric acid levels and subsequent development of cancer in 493,281 individuals: findings from the AMORIS Study

Circulating uric acid levels and subsequent development of cancer in 493,281 individuals: findings from the AMORIS Study

https://doi.org/10.18632/oncotarget.16198

Andrew Yiu, Mieke Van Hemelrijck, Hans Garmo, Lars Holmberg, Håkan Malmström, Mats Lambe, Niklas Hammar, Göran Walldius, Ingmar Jungner,  and Wahyu Wulaningsih
42332-42342
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preclinical development of G1T38: A novel, potent and selective inhibitor of cyclin dependent kinases 4/6 for use as an oral antineoplastic in patients with CDK4/6 sensitive tumors

Preclinical development of G1T38: A novel, potent and selective inhibitor of cyclin dependent kinases 4/6 for use as an oral antineoplastic in patients with CDK4/6 sensitive tumors

https://doi.org/10.18632/oncotarget.16216

John E. Bisi, Jessica A. Sorrentino, Jamie L. Jordan, David D. Darr, Patrick J. Roberts, Francis X. Tavares,  and Jay C. Strum
42343-42358
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Drug-carrying microbubbles as a theranostic tool in convection-enhanced delivery for brain tumor therapy

Drug-carrying microbubbles as a theranostic tool in convection-enhanced delivery for brain tumor therapy

https://doi.org/10.18632/oncotarget.16218

Pin-Yuan Chen, Chih-Kuang Yeh, Po-Hung Hsu, Chung-Yin Lin, Chiung-Yin Huang, Kuo-Chen Wei,  and Hao-Li Liu
42359-42371
Abstract  |  PDF  |  HTML  |  Order a Reprint

Treatment for retropharyngeal metastatic undifferentiated squamous cell carcinoma from an unknown primary site: results of a prospective study with irradiation to nasopharyngeal mucosa plus bilateral neck

Treatment for retropharyngeal metastatic undifferentiated squamous cell carcinoma from an unknown primary site: results of a prospective study with irradiation to nasopharyngeal mucosa plus bilateral neck

https://doi.org/10.18632/oncotarget.16344

Chengrun Du, Hongmei Ying, Youwang Zhang, Yafang Huang, Ruiping Zhai,  and Chaosu Hu
42372-42381
Abstract  |  PDF  |  HTML  |  Order a Reprint

IK channel activation increases tumor growth and induces differential behavioral responses in two breast epithelial cell lines

IK channel activation increases tumor growth and induces differential behavioral responses in two breast epithelial cell lines

https://doi.org/10.18632/oncotarget.16389

Amy E. Thurber, Michaela Nelson, Crystal L. Frost, Michael Levin, William J. Brackenbury,  and David L. Kaplan
42382-42397
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High expression of miR-125b-2 and SNORD116 noncoding RNA clusters characterize ERG-related B cell precursor acute lymphoblastic leukemia

High expression of miR-125b-2 and SNORD116 noncoding RNA clusters characterize ERG-related B cell precursor acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.16392

Elena Vendramini, Marco Giordan, Emanuela Giarin, Barbara Michielotto, Grazia Fazio, Gianni Cazzaniga, Andrea Biondi, Daniela Silvestri, Maria Grazia Valsecchi, Martina U. Muckenthaler, Andreas E. Kulozik, Valter Gattei, Shai Izraeli, Giuseppe Basso,  and Geertruy te Kronnie
42398-42413
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Type Iγ phosphatidylinositol phosphate kinase regulates PD-L1 expression by activating NF-κB

Type Iγ phosphatidylinositol phosphate kinase regulates PD-L1 expression by activating NF-κB

https://doi.org/10.18632/oncotarget.17123

Junli Xue, Chunhua Chen, Manlong Qi, Yan Huang, Lin Wang, Yong Gao, Haidong Dong,  and Kun Ling
42414-42427
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MET exon 14 mutations as targets in routine molecular analysis of primary sarcomatoid carcinoma of the lung

MET exon 14 mutations as targets in routine molecular analysis of primary sarcomatoid carcinoma of the lung

https://doi.org/10.18632/oncotarget.16403

Raphaël Saffroy, Vincent Fallet, Nicolas Girard, Julien Mazieres, Denis Moro Sibilot, Sylvie Lantuejoul, Isabelle Rouquette, Françoise Thivolet-Bejui, Thibaut Vieira, Martine Antoine, Jacques Cadranel, Antoinette Lemoine,  and Marie Wislez
42428-42437
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer

Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer

https://doi.org/10.18632/oncotarget.17124

Miriam S. Butler, Mani Roshan-Moniri, Michael Hsing, Desmond Lau, Ari Kim, Paul Yen, Marta Mroczek, Mannan Nouri, Scott Lien, Peter Axerio-Cilies, Kush Dalal, Clement Yau, Fariba Ghaidi, Yubin Guo, Takeshi Yamazaki, Sam Lawn, Martin E. Gleave, Cheryl Y. Gregory-Evans, Lawrence P. McIntosh, Michael E. Cox, Paul S. Rennie,  and Artem Cherkasov
42438-42454
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinicopathologic study of invasive micropapillary carcinoma of the breast

Clinicopathologic study of invasive micropapillary carcinoma of the breast

https://doi.org/10.18632/oncotarget.16405

Shen-li Tang, Ji-qiao Yang, Zheng-gui Du, Qiu-wen Tan, Yu-ting Zhou, Di Zhang,  and Qing Lv
42455-42465
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Synergistic anti-tumor effect of bullfrog sialic acid-binding lectin and pemetrexed in malignant mesothelioma

Synergistic anti-tumor effect of bullfrog sialic acid-binding lectin and pemetrexed in malignant mesothelioma

https://doi.org/10.18632/oncotarget.17198

Toshiyuki Satoh, Takeo Tatsuta, Shigeki Sugawara, Akiyoshi Hara,  and Masahiro Hosono
42466-42477
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Tissue recommendations for precision cancer therapy using next generation sequencing: a comprehensive single cancer center’s experiences

Tissue recommendations for precision cancer therapy using next generation sequencing: a comprehensive single cancer center’s experiences

https://doi.org/10.18632/oncotarget.17199

Minho Cho, Soomin Ahn, Mineui Hong, Heejin Bang, Michael Van Vrancken, Seungtae Kim, Jeeyun Lee, Se Hoon Park, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Won Ki Kang, Jong-Mu Sun, Se Hoon Lee, Myung-Ju Ahn, Keunchil Park, Duk Hwan Kim, Seunggwan Lee, Woongyang Park,  and Kyoung-Mee Kim
42478-42486
Abstract  |  PDF  |  HTML  |  Order a Reprint

Local recurrences at the anastomotic area are clonally related to the primary tumor in sporadic colorectal carcinoma

Local recurrences at the anastomotic area are clonally related to the primary tumor in sporadic colorectal carcinoma

https://doi.org/10.18632/oncotarget.17200

Efsevia Vakiani, Ronak H. Shah, Michael F. Berger, Alvin P. Makohon-Moore, Johannes G. Reiter, Irina Ostrovnaya, Marc A. Attiyeh, Andrea Cercek, Jinru Shia, Christine A. Iacobuzio-Donahue, David B. Solit,  and Martin R. Weiser
42487-42494
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combination therapy with micellarized cyclopamine and temozolomide attenuate glioblastoma growth through Gli1 down-regulation

Combination therapy with micellarized cyclopamine and temozolomide attenuate glioblastoma growth through Gli1 down-regulation

https://doi.org/10.18632/oncotarget.17205

Yu-Jie Liu, Ying-Cong Ma, Wen-Jie Zhang, Zhen-Zhen Yang, De-Sheng Liang, Zhi-Fu Wu,  and Xian-Rong Qi
42495-42509
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Eg5 inhibitor YL001 induces mitotic arrest and inhibits tumor proliferation

Eg5 inhibitor YL001 induces mitotic arrest and inhibits tumor proliferation

https://doi.org/10.18632/oncotarget.17207

Yufei Wang, Xingyu Wu, Mufeng Du, Xi Chen, Xianling Ning, Hong Chen, Siyuan Wang, Jia Liu, Zhenming Liu, Ridong Li, Ge Fu, Chunguang Wang, Michael A. McNutt, Demin Zhou,  and Yuxin Yin
42510-42524
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of the miRNA-mRNA regulatory network of small cell osteosarcoma based on RNA-seq

Identification of the miRNA-mRNA regulatory network of small cell osteosarcoma based on RNA-seq

https://doi.org/10.18632/oncotarget.17208

Lin Xie, Yedan Liao, Lida Shen, Fengdi Hu, Sunlin Yu, Yonghong Zhou, Ya Zhang, Yihao Yang, Dongqi Li, Minyan Ren, Zhongqin Yuan,  and Zuozhang Yang
42525-42536
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RNA sequencing analyses reveal novel differentially expressed genes and pathways in pancreatic cancer

RNA sequencing analyses reveal novel differentially expressed genes and pathways in pancreatic cancer

https://doi.org/10.18632/oncotarget.16451

Yixiang Mao, Jianjun Shen, Yue Lu, Kevin Lin, Huamin Wang, Yanan Li, Ping Chang, Mary G. Walker,  and Donghui Li
42537-42547
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association of body mass index with ER, PR and 14-3-3σ expression in tumor and stroma of type I and type II endometrial carcinoma

Association of body mass index with ER, PR and 14-3-3σ expression in tumor and stroma of type I and type II endometrial carcinoma

https://doi.org/10.18632/oncotarget.17209

Joseph F. Peevey, Brandon-Luke L. Seagle, Kruti P. Maniar,  and J. Julie Kim
42548-42559
Abstract  |  PDF  |  HTML  |  Order a Reprint

Analysis of STAT3 post-translational modifications (PTMs) in human prostate cancer with different Gleason Score

Analysis of STAT3 post-translational modifications (PTMs) in human prostate cancer with different Gleason Score

https://doi.org/10.18632/oncotarget.17245

Rossana Cocchiola, Donatella Romaniello, Caterina Grillo, Fabio Altieri, Marcello Liberti, Fabio Massimo Magliocca, Silvia Chichiarelli, Ilaria Marrocco, Giuseppe Borgoni, Giacomo Perugia,  and Margherita Eufemi
42560-42570
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CK2 and PI3K are direct molecular targets of quercetin in chronic lymphocytic leukaemia

CK2 and PI3K are direct molecular targets of quercetin in chronic lymphocytic leukaemia

https://doi.org/10.18632/oncotarget.17246

Maria Russo, Alfonsina Milito, Carmela Spagnuolo, Virginia Carbone, Anders Rosén, Paola Minasi, Fabio Lauria,  and Gian Luigi Russo
42571-42587
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GALNT6 expression enhances aggressive phenotypes of ovarian cancer cells by regulating EGFR activity

GALNT6 expression enhances aggressive phenotypes of ovarian cancer cells by regulating EGFR activity

https://doi.org/10.18632/oncotarget.16585

Tzu-Chi Lin, Syue-Ting Chen, Min-Chuan Huang, John Huang, Chia-Lang Hsu, Hsueh-Fen Juan, Ho-Hsiung Lin,  and Chi-Hau Chen
42588-42601
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Anti-cancer activity of Annexin V in murine melanoma model by suppressing tumor angiogenesis

Anti-cancer activity of Annexin V in murine melanoma model by suppressing tumor angiogenesis

https://doi.org/10.18632/oncotarget.16645

Xuerui Zhang, Lina Huo, Haibo Jin, Yuheng Han, Jie Wang, Yanjun Zhang, Xinghuan Lai, Ziwei Le, Jing Zhang,  and Zichun Hua
42602-42612
Abstract  |  PDF  |  HTML  |  Order a Reprint

NGS based identification of mutational hotspots for targeted therapy in anaplastic thyroid carcinoma

NGS based identification of mutational hotspots for targeted therapy in anaplastic thyroid carcinoma

https://doi.org/10.18632/oncotarget.17300

Vera Tiedje, Saskia Ting, Thomas Herold, Sarah Synoracki, Soeren Latteyer, Lars C. Moeller, Denise Zwanziger, Martin Stuschke, Dagmar Fuehrer,  and Kurt Werner Schmid
42613-42620
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

EGFR-induced phosphorylation of type Iγ phosphatidylinositol phosphate kinase promotes pancreatic cancer progression

EGFR-induced phosphorylation of type Iγ phosphatidylinositol phosphate kinase promotes pancreatic cancer progression

https://doi.org/10.18632/oncotarget.16730

Chunhua Chen, Xiangling Wang, Juemin Fang, Junli Xue, Xunhao Xiong, Yan Huang, Jinghua Hu,  and Kun Ling
42621-42637
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Differential expression of miR-195-5p in collapse of steroid-induced osteonecrosis of the femoral head

Differential expression of miR-195-5p in collapse of steroid-induced osteonecrosis of the femoral head

https://doi.org/10.18632/oncotarget.17333

Pengfei Li, Pei Zhai, Zengjie Ye, Peng Deng, Yueguang Fan, Yirong Zeng, Zhihui Pang, Jianchun Zeng, Jie Li,  and Wenjun Feng
42638-42647
Abstract  |  PDF  |  HTML  |  Order a Reprint

Naoling decoction restores cognitive function by inhibiting the neuroinflammatory network in a rat model of Alzheimer’s disease

Naoling decoction restores cognitive function by inhibiting the neuroinflammatory network in a rat model of Alzheimer’s disease

https://doi.org/10.18632/oncotarget.17337

Zian Xia, Weijun Peng, Shunhua Cheng, Bingwu Zhong, Chenxia Sheng, Chunhu Zhang, Wei Gong, Shuai Cheng, Jun Li,  and Zhe Wang
42648-42663
Abstract  |  PDF  |  HTML  |  Order a Reprint

Synthetic lethality of glutaminolysis inhibition, autophagy inactivation and asparagine depletion in colon cancer

Synthetic lethality of glutaminolysis inhibition, autophagy inactivation and asparagine depletion in colon cancer

https://doi.org/10.18632/oncotarget.16844

Jiaqiu Li, Ping Song, Liyuan Zhu, Neelum Aziz, Qiyin Zhou, Yulong Zhang, Wenxia Xu, Lifeng Feng, Dingwei Chen, Xian Wang,  and Hongchuan Jin
42664-42672
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oocyte exposure to ZnO nanoparticles inhibits early embryonic development through the γ-H2AX and NF-κB signaling pathways

Oocyte exposure to ZnO nanoparticles inhibits early embryonic development through the γ-H2AX and NF-κB signaling pathways

https://doi.org/10.18632/oncotarget.17349

Jing Liu, Yong Zhao, Wei Ge, Pengfei Zhang, Xinqi Liu, Weidong Zhang, Yanan Hao, Shuai Yu, Lan Li, Meiqiang Chu, Lingjiang Min, Hongfu Zhang,  and Wei Shen
42673-42692
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Characteristics of delayed intracerebral hemorrhage after ventriculoperitoneal shunt insertion

Characteristics of delayed intracerebral hemorrhage after ventriculoperitoneal shunt insertion

https://doi.org/10.18632/oncotarget.17444

Weiyi Gong, Li Xu, Peng Yang, Zhengquan Yu, Zhong Wang, Gang Chen, Shiming Zhang,  and Jiang Wu
42693-42699
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The generation and functional characterization of induced pluripotent stem cells from human intervertebral disc nucleus pulposus cells

The generation and functional characterization of induced pluripotent stem cells from human intervertebral disc nucleus pulposus cells

https://doi.org/10.18632/oncotarget.17446

Yanxia Zhu, Yuhong Liang, Hongxia Zhu, Cuihong Lian, Liang Wang, Yiwei Wang, Hongsheng Gu, Guangqian Zhou,  and Xiaoping Yu
42700-42711
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Characterization of mouse serum exosomal small RNA content: The origins and their roles in modulating inflammatory response

Characterization of mouse serum exosomal small RNA content: The origins and their roles in modulating inflammatory response

https://doi.org/10.18632/oncotarget.17448

Xin Zhou, Zinan Jiao, Juling Ji, Shuyuan Li, Xiaodi Huang, Xiaoshuang Lu, Heng Zhao, Jingwen Peng, Xinya Chen, Qiuhong Ji,  and Yuhua Ji
42712-42727
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The palmitoylation of the N-terminal extracellular Cys37 mediates the nuclear translocation of VPAC1 contributing to its anti-apoptotic activity

The palmitoylation of the N-terminal extracellular Cys37 mediates the nuclear translocation of VPAC1 contributing to its anti-apoptotic activity

https://doi.org/10.18632/oncotarget.17449

Rongjie Yu, Hongyu Liu, Xinhe Peng, Yue Cui, Suqin Song, Like Wang, Huahua Zhang, An Hong,  and Tianhong Zhou
42728-42741
Abstract  |  PDF  |  HTML  |  Order a Reprint

Combating acquired resistance to trastuzumab by an anti-ErbB2 fully human antibody

Combating acquired resistance to trastuzumab by an anti-ErbB2 fully human antibody

https://doi.org/10.18632/oncotarget.17451

Chao Wang, Lingfei Wang, Xiaojie Yu, Yajun Zhang, Yanchun Meng, Huajing Wang, Yang Yang, Jie Gao, Huafeng Wei, Jian Zhao, Cuihua Lu, Han Chen, Yanping Sun,  and Bohua Li
42742-42751
Abstract  |  PDF  |  HTML  |  Order a Reprint

A transcriptional complex composed of ER(α), GATA3, FOXA1 and ELL3 regulates IL-20 expression in breast cancer cells

A transcriptional complex composed of ER(α), GATA3, FOXA1 and ELL3 regulates IL-20 expression in breast cancer cells

https://doi.org/10.18632/oncotarget.17459

Jae Yong Lee, Young Joon Park, Nuri Oh, Kyu Bum Kwack,  and Kyung-Soon Park
42752-42760
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Large-scale clinical validation of biomarkers for pancreatic cancer using a mass spectrometry-based proteomics approach

Large-scale clinical validation of biomarkers for pancreatic cancer using a mass spectrometry-based proteomics approach

https://doi.org/10.18632/oncotarget.17463

Jisook Park, Eunjung Lee, Kyoung-Jin Park, Hyung-Doo Park, Jong-Won Kim, Hye In Woo, Kwang Hyuck Lee, Kyu-Taek Lee, Jong Kyun Lee, Joon-Oh Park, Young Suk Park, Jin Seok Heo, Seong Ho Choi, Dong Wook Choi, Kee-Taek Jang,  and Soo-Youn Lee
42761-42771
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Charge reversible calcium phosphate lipid hybrid nanoparticle for siRNA delivery

Charge reversible calcium phosphate lipid hybrid nanoparticle for siRNA delivery

https://doi.org/10.18632/oncotarget.17484

Rong-Qiao Cai, Dao-Zhou Liu, Han Cui, Ying Cheng, Miao Liu, Bang-Le Zhang, Qi-Bing Mei,  and Si-Yuan Zhou
42772-42788
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Assessment of citalopram and escitalopram on neuroblastoma cell lines: Cell toxicity and gene modulation

Assessment of citalopram and escitalopram on neuroblastoma cell lines: Cell toxicity and gene modulation

https://doi.org/10.18632/oncotarget.17050

Laurent Sakka, Nathalie Delétage, Maryse Chalus, Youssef Aissouni, Valérie Sylvain-Vidal, Stéphane Gobron,  and Guillaume Coll
42789-42807
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mechanism of oxidative stress p38MAPK-SGK1 signaling axis in experimental autoimmune encephalomyelitis (EAE)

Mechanism of oxidative stress p38MAPK-SGK1 signaling axis in experimental autoimmune encephalomyelitis (EAE)

https://doi.org/10.18632/oncotarget.17057

Liang Wang, Bin Li, Mo-Yuan Quan, Lin Li, Yuan Chen, Guo-Jun Tan, Jing Zhang, Xiao-Peng Liu,  and Li Guo
42808-42816
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Paraoxonase-1 (PON1) induces metastatic potential and apoptosis escape via its antioxidative function in lung cancer cells

Paraoxonase-1 (PON1) induces metastatic potential and apoptosis escape via its antioxidative function in lung cancer cells

https://doi.org/10.18632/oncotarget.17069

Mark Borris D. Aldonza, Yeon Sung Son, Hye-Jin Sung, Jung Mo Ahn, Young-Jin Choi, Yong-In Kim, Sukki Cho,  and Je-Yoel Cho
42817-42835
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A systematic approach for peptide characterization of B-cell receptor in chronic lymphocytic leukemia cells

A systematic approach for peptide characterization of B-cell receptor in chronic lymphocytic leukemia cells

https://doi.org/10.18632/oncotarget.17076

Paula Díez, Nieves Ibarrola, Rosa M. Dégano, Quentin Lécrevisse, Arancha Rodriguez-Caballero, Ignacio Criado, Wendy G. Nieto, Rafael Góngora, Marcos González, Julia Almeida, Alberto Orfao,  and Manuel Fuentes
42836-42846
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A subset of microRNAs defining the side population of a human malignant mesothelioma cell line

A subset of microRNAs defining the side population of a human malignant mesothelioma cell line

https://doi.org/10.18632/oncotarget.17086

Myung-Chul Kim, Na-Yon Kim, Yu-Ri Seo,  and Yongbaek Kim
42847-42856
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells

Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells

https://doi.org/10.18632/oncotarget.17143

James Meehan, Carol Ward, Arran Turnbull, Jimi Bukowski-Wills, Andrew J. Finch, Edward J. Jarman, Chrysi Xintaropoulou, Carlos Martinez-Perez, Mark Gray, Matthew Pearson, Peter Mullen, Claudiu T. Supuran, Fabrizio Carta, David J. Harrison, Ian H. Kunkler,  and Simon P. Langdon
42857-42875
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Trends in the management and outcomes of patients admitted with acute coronary syndrome complicated by cardiogenic shock over the past decade: Real world data from the acute coronary syndrome Israeli survey (ACSIS)

Trends in the management and outcomes of patients admitted with acute coronary syndrome complicated by cardiogenic shock over the past decade: Real world data from the acute coronary syndrome Israeli survey (ACSIS)

https://doi.org/10.18632/oncotarget.17152

Eran Kalmanovich, Alex Blatt, Svetlana Brener, Meital Shlezinger, Nir Shlomo, Zvi Vered, Hanoch Hod, Ilan Goldenberg,  and Gabby Elbaz-Greener
42876-42886
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HIF-2α dictates the susceptibility of pancreatic cancer cells to TRAIL by regulating survivin expression

HIF-2α dictates the susceptibility of pancreatic cancer cells to TRAIL by regulating survivin expression

https://doi.org/10.18632/oncotarget.17157

Nanae Harashima, Keizo Takenaga, Miho Akimoto,  and Mamoru Harada
42887-42900
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Biglycan expression in the melanoma microenvironment promotes invasiveness via increased tissue stiffness inducing integrin-β1 expression

Biglycan expression in the melanoma microenvironment promotes invasiveness via increased tissue stiffness inducing integrin-β1 expression

https://doi.org/10.18632/oncotarget.17160

Hana Andrlová, Justin Mastroianni, Josef Madl, Johannes S. Kern, Wolfgang Melchinger, Heide Dierbach, Florian Wernet, Marie Follo, Kristin Technau-Hafsi, Cristina Has, Venugopal Rao Mittapalli, Marco Idzko, Ricarda Herr, Tilman Brummer, Hendrik Ungefroren, Hauke Busch, Melanie Boerries, Andreas Narr, Gabriele Ihorst, Claire Vennin, Annette Schmitt-Graeff, Susana Minguet, Paul Timpson, Justus Duyster, Frank Meiss, Winfried Römer,  and Robert Zeiser
42901-42916
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Post-operative radiotherapy is beneficial for T1/T2 triple negative breast cancer patients with four or more positive lymph nodes

Post-operative radiotherapy is beneficial for T1/T2 triple negative breast cancer patients with four or more positive lymph nodes

https://doi.org/10.18632/oncotarget.17170

Lin Chen, Jinfeng Zhang, Jiayi chen, Lili Liu, Lili Liang, Zhiyi Shangguan,  and Dandan Wang
42917-42925
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Self-assembling nanoparticles encapsulating zoledronic acid inhibit mesenchymal stromal cells differentiation, migration and secretion of proangiogenic factors and their interactions with prostate cancer cells

Self-assembling nanoparticles encapsulating zoledronic acid inhibit mesenchymal stromal cells differentiation, migration and secretion of proangiogenic factors and their interactions with prostate cancer cells

https://doi.org/10.18632/oncotarget.17216

Cinzia Borghese, Naike Casagrande, Eliana Pivetta, Alfonso Colombatti, Mariarosaria Boccellino, Evzen Amler, Nicola Normanno, Michele Caraglia, Giuseppe De Rosa,  and Donatella Aldinucci
42926-42938
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

E6AP promotes prostate cancer by reducing p27 expression

E6AP promotes prostate cancer by reducing p27 expression

https://doi.org/10.18632/oncotarget.17224

Dinesh Raghu, Piotr Jan Paul, Twishi Gulati, Siddhartha Deb, Christine Khoo, Andrea Russo, Enzo Gallo, Giovanni Blandino, Ai-Leen Chan, Elena Takano, Shahneen K. Sandhu, Stephen B. Fox, Scott Williams, Sue Haupt, Cristina Gamell,  and Ygal Haupt
42939-42948
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Apelin: A putative novel predictive biomarker for bevacizumab response in colorectal cancer

Apelin: A putative novel predictive biomarker for bevacizumab response in colorectal cancer

https://doi.org/10.18632/oncotarget.17306

Linda Zuurbier, Arman Rahman, Martijn Cordes, Jennifer Scheick, Tse J. Wong, François Rustenburg, Jesu Christopher Joseph, Peter Dynoodt, Rory Casey, Paul Drillenburg, Michael Gerhards, Ana Barat, Rut Klinger, Bozena Fender, Darran P. O’Connor, Johannes Betge, Matthias P. Ebert, Timo Gaiser, Jochen H.M. Prehn, Arjan W. Griffioen, Nicole C. T. van Grieken, Bauke Ylstra, Annette T. Byrne, Laurens G. van der Flier, William M. Gallagher,  and Ruben Postel
42949-42961
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Differentiation of pancreatic neuroendocrine carcinoma from pancreatic ductal adenocarcinoma using magnetic resonance imaging: The value of contrast-enhanced and diffusion weighted imaging

Differentiation of pancreatic neuroendocrine carcinoma from pancreatic ductal adenocarcinoma using magnetic resonance imaging: The value of contrast-enhanced and diffusion weighted imaging

https://doi.org/10.18632/oncotarget.17309

Chuangen Guo, Xiao Chen, Zhongqiu Wang, Wenbo Xiao, Qidong Wang, Ke Sun,  and Xiaoling Zhuge
42962-42973
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Stratification according to recursive partitioning analysis predicts outcome in newly diagnosed glioblastomas

Stratification according to recursive partitioning analysis predicts outcome in newly diagnosed glioblastomas

https://doi.org/10.18632/oncotarget.17322

Fan Yang, Pei Yang, Chuanbao Zhang, Yongzhi Wang, Wei Zhang, Huimin Hu, Zhiliang Wang, Xiaoguang Qiu,  and Tao Jiang
42974-42982
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gene co-expression network reveals shared modules predictive of stage and grade in serous ovarian cancers

Gene co-expression network reveals shared modules predictive of stage and grade in serous ovarian cancers

https://doi.org/10.18632/oncotarget.17785

Qian Sun, Haiyue Zhao, Cong Zhang, Ting Hu, Jianli Wu, Xingguang Lin, Danfeng Luo, Changyu Wang, Li Meng, Ling Xi, Kezhen Li, Junbo Hu, Ding Ma,  and Tao Zhu
42983-42996
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IL13RA2 targeted alpha particle therapy against glioblastomas

IL13RA2 targeted alpha particle therapy against glioblastomas

https://doi.org/10.18632/oncotarget.17792

Anirudh Sattiraju, Kiran Kumar Solingapuram Sai, Ang Xuan, Darpan N. Pandya, Frankis G. Almaguel, Thaddeus J. Wadas, Denise M. Herpai, Waldemar Debinski,  and Akiva Mintz
42997-43007
Abstract  |  PDF  |  HTML  |  Order a Reprint

Restoration of p53 using the novel MDM2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells

Restoration of p53 using the novel MDM2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells

https://doi.org/10.18632/oncotarget.17398

Haibo Chen, Dingyuan Luo, Lin Zhang, Xiaofeng Lin, Qiuyun Luo, Hanjie Yi, Jing Wang, Xianglei Yan, Baoxia Li, Yuelei Chen, Xingguang Liu, Hong Zhang, Sheng Liu, Miaozhen Qiu, Dajun Yang,  and Ningyi Jiang
43008-43022
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Follistatin-like protein 1 promotes inflammatory reactions in nucleus pulposus cells by interacting with the MAPK and NFκB signaling pathways

Follistatin-like protein 1 promotes inflammatory reactions in nucleus pulposus cells by interacting with the MAPK and NFκB signaling pathways

https://doi.org/10.18632/oncotarget.17400

Yi Liu, Jianlu Wei, Yunpeng Zhao, Yuanqiang Zhang, Yingguang Han, Bin Chen, Kaiyuan Cheng, Jialin Jia, Lin Nie,  and Lei Cheng
43023-43034
Abstract  |  PDF  |  HTML  |  Order a Reprint

Gene expression signature of Gleason score is associated with prostate cancer outcomes in a radical prostatectomy cohort

Gene expression signature of Gleason score is associated with prostate cancer outcomes in a radical prostatectomy cohort

https://doi.org/10.18632/oncotarget.17428

Mina A. Jhun, Milan S. Geybels, Jonathan L. Wright, Suzanne Kolb, Craig April, Marina Bibikova, Elaine A. Ostrander, Jian-Bing Fan, Ziding Feng,  and Janet L. Stanford
43035-43047
Abstract  |  PDF  |  HTML  |  Order a Reprint

6-mercaptopurine promotes energetic failure in proliferating T cells

6-mercaptopurine promotes energetic failure in proliferating T cells

https://doi.org/10.18632/oncotarget.17889

Ana A. Fernández-Ramos, Catherine Marchetti-Laurent, Virginie Poindessous, Samantha Antonio, Pierre Laurent-Puig, Sylvie Bortoli, Marie-Anne Loriot,  and Nicolas Pallet
43048-43060
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Establishment of mouse neuron and microglial cell co-cultured models and its action mechanism

Establishment of mouse neuron and microglial cell co-cultured models and its action mechanism

https://doi.org/10.18632/oncotarget.17898

Bo Zhang, Yunfeng Yang, Jun Tang, Yihao Tao, Bing Jiang, Zhi Chen, Hua Feng, Liming Yang,  and Gang Zhu
43061-43067
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of polymorphisms in 12q24.1, ACAD10, and BRAP as novel genetic determinants of blood pressure in Japanese by exome-wide association studies

Identification of polymorphisms in 12q24.1, ACAD10, and BRAP as novel genetic determinants of blood pressure in Japanese by exome-wide association studies

https://doi.org/10.18632/oncotarget.17474

Yoshiji Yamada, Jun Sakuma, Ichiro Takeuchi, Yoshiki Yasukochi, Kimihiko Kato, Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Masaaki Muramatsu, Motoji Sawabe, Yoshinori Fujiwara, Yu Taniguchi, Shuichi Obuchi, Hisashi Kawai, Shoji Shinkai, Seijiro Mori, Tomio Arai,  and Masashi Tanaka
43068-43079
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Polymorphisms in BMP2/BMP4, with estimates of mean lung dose, predict radiation pneumonitis among patients receiving definitive radiotherapy for non-small cell lung cancer

Polymorphisms in BMP2/BMP4, with estimates of mean lung dose, predict radiation pneumonitis among patients receiving definitive radiotherapy for non-small cell lung cancer

https://doi.org/10.18632/oncotarget.17904

Ju Yang, Ting Xu, Daniel R. Gomez, Xianglin Yuan, Quynh-Nhu Nguyen, Melenda Jeter, Yipeng Song, Stephen Hahn,  and Zhongxing Liao
43080-43090
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

An anti-cancer WxxxE-containing azurin polypeptide inhibits Rac1-dependent STAT3 and ERK/GSK-3β signaling in breast cancer cells

An anti-cancer WxxxE-containing azurin polypeptide inhibits Rac1-dependent STAT3 and ERK/GSK-3β signaling in breast cancer cells

https://doi.org/10.18632/oncotarget.17759

Zhe Zhang, Zhiyong Luo, Wenpu Min, Lin Zhang, Yaqun Wu,  and Xiaopeng Hu
43091-43103
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The correlation between pulmonary fibrosis and methylation of peripheral Smad3 in cases of pigeon breeder's lung in a Chinese Uygur population

The correlation between pulmonary fibrosis and methylation of peripheral Smad3 in cases of pigeon breeder's lung in a Chinese Uygur population

https://doi.org/10.18632/oncotarget.17763

Chao Wu, Wei Ding, Qifeng Li, Wenyi Wang, Mingqin Deng, Rong Jin, Baosen Pang,  and Xiaohong Yang
43104-43113
Abstract  |  PDF  |  HTML  |  Order a Reprint

Accumulation of prohibitin is a common cellular response to different stressing stimuli and protects melanoma cells from ER stress and chemotherapy-induced cell death

Accumulation of prohibitin is a common cellular response to different stressing stimuli and protects melanoma cells from ER stress and chemotherapy-induced cell death

https://doi.org/10.18632/oncotarget.17810

Tharcisio Citrangulo Tortelli Junior, Lyris Martins Franco de Godoy, Gustavo Antonio de Souza, Diego Bonatto, Andreia Hanada Otake, Renata de Freitas Saito, Jose Cesar Rosa, Lewis Joel Greene,  and Roger Chammas
43114-43129
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Three hematological indexes that may serve as prognostic indicators in patients with primary, high-grade, appendicular osteosarcoma

Three hematological indexes that may serve as prognostic indicators in patients with primary, high-grade, appendicular osteosarcoma

https://doi.org/10.18632/oncotarget.17811

Keqi Hu, Zhan Wang, Peng Lin, Haiyong Ren, Lingling Sun, Hengyuan Li, Binghao Li, Shengdong Wang, Siyuan Tengwang, Xingzhi Zhou,  and Zhaoming Ye
43130-43139
Abstract  |  PDF  |  HTML  |  Order a Reprint

Epistatic SNP interaction of ERCC6 with ERCC8 and their joint protein expression contribute to gastric cancer/atrophic gastritis risk

Epistatic SNP interaction of ERCC6 with ERCC8 and their joint protein expression contribute to gastric cancer/atrophic gastritis risk

https://doi.org/10.18632/oncotarget.17814

Jing-Jing Jing, You-Zhu Lu, Li-Ping Sun, Jing-Wei Liu, Yue-Hua Gong, Qian Xu, Nan-Nan Dong,  and Yuan Yuan
43140-43152
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IL-17RC is critically required to maintain baseline A20 production to repress JNK isoform-dependent tumor-specific proliferation

IL-17RC is critically required to maintain baseline A20 production to repress JNK isoform-dependent tumor-specific proliferation

https://doi.org/10.18632/oncotarget.17820

Chi Yan, Yang Lei, Tong-Jun Lin, David W. Hoskin, Averil Ma,  and Jun Wang
43153-43168
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prediction of cervical cancer recurrence using textural features extracted from 18F-FDG PET images acquired with different scanners

Prediction of cervical cancer recurrence using textural features extracted from 18F-FDG PET images acquired with different scanners

https://doi.org/10.18632/oncotarget.17856

Sylvain Reuzé, Fanny Orlhac, Cyrus Chargari, Christophe Nioche, Elaine Limkin, François Riet, Alexandre Escande, Christine Haie-Meder, Laurent Dercle, Sébastien Gouy, Irène Buvat, Eric Deutsch,  and Charlotte Robert
43169-43179
Abstract  |  PDF  |  HTML  |  Order a Reprint

Characterization of the release and biological significance of cell-free DNA from breast cancer cell lines

Characterization of the release and biological significance of cell-free DNA from breast cancer cell lines

https://doi.org/10.18632/oncotarget.17858

Wei Wang, Peng Kong, Ge Ma, Li Li, Jin Zhu, Tiansong Xia, Hui Xie, Wenbin Zhou,  and Shui Wang
43180-43191
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Differentiation capacities of skeletal muscle satellite cells in Lantang and Landrace piglets

Differentiation capacities of skeletal muscle satellite cells in Lantang and Landrace piglets

https://doi.org/10.18632/oncotarget.17860

Chun-Qi Gao, Yin-Long Xu, Cheng-Long Jin, Xiao-Chao Hu, Hai-Chang Li, Guang-Xu Xing, Hui-Chao Yan,  and Xiu-Qi Wang
43192-43200
Abstract  |  PDF  |  HTML  |  Order a Reprint

RIP1 is a central signaling protein in regulation of TNF-α/TRAIL mediated apoptosis and necroptosis during Newcastle disease virus infection

RIP1 is a central signaling protein in regulation of TNF-α/TRAIL mediated apoptosis and necroptosis during Newcastle disease virus infection

https://doi.org/10.18632/oncotarget.17970

Ying Liao, Hua-Xia Wang, Xiang Mao, Hongjie Fang, Huang Wang, Yanrong Li, Yingjie Sun, Chun Meng, Lei Tan, Cuiping Song, Xusheng Qiu,  and Chan Ding
43201-43217
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

VEGF-C expression attributes the risk for lymphatic metastases to ovarian cancer patients

VEGF-C expression attributes the risk for lymphatic metastases to ovarian cancer patients

https://doi.org/10.18632/oncotarget.17978

Sascha Kuerti, Leticia Oliveira-Ferrer, Karin Milde-Langosch, Barbara Schmalfeldt, Karen Legler, Linn Woelber, Katharina Prieske, Sven Mahner,  and Fabian Trillsch
43218-43227
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Spindle cell carcinoma: the general demographics, basic clinico-pathologic characteristics, treatment, outcome and prognostic factors

Spindle cell carcinoma: the general demographics, basic clinico-pathologic characteristics, treatment, outcome and prognostic factors

https://doi.org/10.18632/oncotarget.18017

Lei Feng, Deng Cai, Alanuer Muhetaer, Yin-Long Yang, Fei Ren, Mumingjiang Yishake, Hao Zhang, Yuan Fang,  and Alimujiang Wushou
43228-43236
Abstract  |  PDF  |  HTML  |  Order a Reprint

ABCG2 downregulation in glioma stem cells enhances the therapeutic efficacy of demethoxycurcumin

ABCG2 downregulation in glioma stem cells enhances the therapeutic efficacy of demethoxycurcumin

https://doi.org/10.18632/oncotarget.18018

Long Chen, Lei Shi, Wenhua Wang,  and Youxin Zhou
43237-43247
Abstract  |  PDF  |  HTML  |  Order a Reprint

Discoidin domain receptor 1 modulates insulin receptor signaling and biological responses in breast cancer cells

Discoidin domain receptor 1 modulates insulin receptor signaling and biological responses in breast cancer cells

https://doi.org/10.18632/oncotarget.18020

Veronica Vella, Roberta Malaguarnera, Maria Luisa Nicolosi, Chiara Palladino, Cristina Spoleti, Michele Massimino, Paolo Vigneri, Michele Purrello, Marco Ragusa, Andrea Morrione,  and Antonino Belfiore
43248-43270
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The HOTAIR, PRNCR1 and POLR2E polymorphisms are associated with cancer risk: a meta-analysis

The HOTAIR, PRNCR1 and POLR2E polymorphisms are associated with cancer risk: a meta-analysis

https://doi.org/10.18632/oncotarget.14920

Haiyan Chu, Yaoyao Chen, Qinbo Yuan, Qiuhan Hua, Xu Zhang, Meilin Wang, Na Tong, Wei Zhang, Jinfei Chen,  and Zhengdong Zhang
43271-43283
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Meta-Analysis

Prevalence of primary cardiac tumor malignancies in retrospective studies over six decades: a systematic review and meta-analysis

Prevalence of primary cardiac tumor malignancies in retrospective studies over six decades: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.17378

Shuai He, Yide Cao, Wei Qin, Wen Chen, Li Yin, Hao Chai, Zhonghao Tao, Shaowen Tang, Zhibing Qiu,  and Xin Chen
43284-43294
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic role of TET2 deficiency in myelodysplastic syndromes: A meta-analysis

Prognostic role of TET2 deficiency in myelodysplastic syndromes: A meta-analysis

https://doi.org/10.18632/oncotarget.17177

Yun Lin, Zhijuan Lin, Kun Cheng, Zhihong Fang, Zhifeng Li, Yiming Luo,  and Bing Xu
43295-43305
Abstract  |  PDF  |  HTML  |  Order a Reprint

Association between tea consumption and risk of cognitive disorders: A dose-response meta-analysis of observational studies

Association between tea consumption and risk of cognitive disorders: A dose-response meta-analysis of observational studies

https://doi.org/10.18632/oncotarget.17429

Xueying Liu, Xiaoyuan Du, Guanying Han,  and Wenyuan Gao
43306-43321
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Relationship between exposure to PM2.5 and lung cancer incidence and mortality: A meta-analysis

Relationship between exposure to PM2.5 and lung cancer incidence and mortality: A meta-analysis

https://doi.org/10.18632/oncotarget.17313

Feifei Huang, Bing Pan, Jun Wu, Engeng Chen,  and Liying Chen
43322-43331
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Body mass index and persistent pain after breast cancer surgery: findings from the women's healthy eating and living study and a meta-analysis

Body mass index and persistent pain after breast cancer surgery: findings from the women's healthy eating and living study and a meta-analysis

https://doi.org/10.18632/oncotarget.17948

Yuan-Yuan Ding, Peng Yao, Lang Wu, Zhen-Kai Han, Tao Hong, Yong-Qiang Zhu,  and Hong-Xi Li
43332-43343
Abstract  |  PDF  |  HTML  |  Order a Reprint

The significance of microRNA-148/152 family as a prognostic factor in multiple human malignancies: a meta-analysis

The significance of microRNA-148/152 family as a prognostic factor in multiple human malignancies: a meta-analysis

https://doi.org/10.18632/oncotarget.17949

Chenkui Miao, Jianzhong Zhang, Kai Zhao, Chao Liang, Aiming Xu, Jundong Zhu, Yuhao Wang, Yibo Hua, Ye Tian, Shouyong Liu, Chao Zhang, Chao Qin,  and Zengjun Wang
43344-43355
Abstract  |  PDF  |  HTML  |  Order a Reprint

The prognostic value of GLUT1 in cancers: a systematic review and meta-analysis

The prognostic value of GLUT1 in cancers: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.17445

Min Yu, Han Yongzhi, Shengying Chen, Xiaodan Luo, Ye Lin, Yu Zhou, Haosheng Jin, Baohua Hou, Yanying Deng, Lei Tu,  and Zhixiang Jian
43356-43367
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Fertility-sparing uterine lesion resection for young women with gestational trophoblastic neoplasias: single institution experience

Fertility-sparing uterine lesion resection for young women with gestational trophoblastic neoplasias: single institution experience

https://doi.org/10.18632/oncotarget.14727

Xiaoyu Wang, Junjun Yang, Jie Li, Jun Zhao, Tong Ren, Fengzhi Feng, Xirun Wan,  and Yang Xiang
43368-43375
Abstract  |  PDF  |  HTML  |  Order a Reprint

The influence of neoadjuvant chemotherapy on gastric cancer patients’ postoperative infectious complications: What is the negative role played by the intestinal barrier dysfunction?

The influence of neoadjuvant chemotherapy on gastric cancer patients’ postoperative infectious complications: What is the negative role played by the intestinal barrier dysfunction?

https://doi.org/10.18632/oncotarget.14758

Zhiliang Wei, Bin Tan, Shougen Cao, Shanglong Liu, Xiaojie Tan, Zengwu Yao, Na Yin, Jiante Li, Dongfeng Zhang,  and Yanbing Zhou
43376-43388
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of risk factors and the pattern of lower cervical lymph node metastasis in esophageal cancer: implications for radiotherapy target delineation

Identification of risk factors and the pattern of lower cervical lymph node metastasis in esophageal cancer: implications for radiotherapy target delineation

https://doi.org/10.18632/oncotarget.14761

Yijun Luo, Xiaoli Wang, Yuhui Liu, Chengang Wang, Yong Huang, Jinming Yu,  and Minghuan Li
43389-43396
Abstract  |  PDF  |  HTML  |  Order a Reprint

Esophageal luminal stenosis is an independent prognostic factor in esophageal squamous cell carcinoma

Esophageal luminal stenosis is an independent prognostic factor in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.14762

Yu-Shang Yang, Wei-Peng Hu, Peng-Zhi Ni, Wen-Ping Wang, Yong Yuan,  and Long-Qi Chen
43397-43405
Abstract  |  PDF  |  HTML  |  Order a Reprint

Shear wave elastography combined with the thyroid imaging reporting and data system for malignancy risk stratification in thyroid nodules

Shear wave elastography combined with the thyroid imaging reporting and data system for malignancy risk stratification in thyroid nodules

https://doi.org/10.18632/oncotarget.15018

Zhao Liu, Hui Jing, Xue Han, Hua Shao, Yi-Xin Sun, Qiu-Cheng Wang,  and Wen Cheng
43406-43416
Abstract  |  PDF  |  HTML  |  Order a Reprint

Use of social network analysis and global sensitivity and uncertainty analyses to better understand an influenza outbreak

Use of social network analysis and global sensitivity and uncertainty analyses to better understand an influenza outbreak

https://doi.org/10.18632/oncotarget.15076

Jianhua Liu, Hongbo Jiang, Hao Zhang, Chun Guo, Lei Wang, Jing Yang,  and Shaofa Nie
43417-43426
Abstract  |  PDF  |  HTML  |  Order a Reprint

Predictive value of peripheral regulatory T cells in non-small cell lung cancer patients undergoing radiotherapy

Predictive value of peripheral regulatory T cells in non-small cell lung cancer patients undergoing radiotherapy

https://doi.org/10.18632/oncotarget.15238

Chao Liu, Shikai Wu, Xiangying Meng, Guangxian Liu, Dongmei Chen, Yang Cong, Ge Shen, Bing Sun, Wei Wang, Qian Wang, Hongjun Gao,  and Xiaoqing Liu
43427-43438
Abstract  |  PDF  |  HTML  |  Order a Reprint

Outcomes of metastatic spinal cord compression secondary to primary hepatocellular carcinoma with multidisciplinary treatments

Outcomes of metastatic spinal cord compression secondary to primary hepatocellular carcinoma with multidisciplinary treatments

https://doi.org/10.18632/oncotarget.15708

Shaohui He, Haifeng Wei, Yifei Ma, Jian Zhao, Wei Xu,  and Jianru Xiao
43439-43449
Abstract  |  PDF  |  HTML  |  Order a Reprint

The challenge in treating locally recurrent T3-4 nasopharyngeal carcinoma: the survival benefit and severe late toxicities of re-irradiation with intensity-modulated radiotherapy

The challenge in treating locally recurrent T3-4 nasopharyngeal carcinoma: the survival benefit and severe late toxicities of re-irradiation with intensity-modulated radiotherapy

https://doi.org/10.18632/oncotarget.15896

Yun-Ming Tian, Wei-Zeng Huang, Xia Yuan, Li Bai, Chong Zhao,  and Fei Han
43450-43457
Abstract  |  PDF  |  HTML  |  Order a Reprint

In-vivo relation between plasma concentration of sorafenib and its safety in Chinese patients with metastatic renal cell carcinoma: a single-center clinical study

In-vivo relation between plasma concentration of sorafenib and its safety in Chinese patients with metastatic renal cell carcinoma: a single-center clinical study

https://doi.org/10.18632/oncotarget.16465

Haixing Mai, Jun Huang, Yuanyuan Zhang, Nang Qu, Hengyan Qu, Guo-hui Mei, Jiannan Liu, Xiaojie Xu,  and Lijun Chen
43458-43469
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

Long non-coding RNAs in cutaneous melanoma: clinical perspectives

Long non-coding RNAs in cutaneous melanoma: clinical perspectives

https://doi.org/10.18632/oncotarget.16478

Eva Hulstaert, Lieve Brochez, Pieter-Jan Volders, Jo Vandesompele,  and Pieter Mestdagh
43470-43480
Abstract  |  PDF  |  HTML  |  Order a Reprint

Peritoneal carcinomatosis: limits of diagnosis and the case for liquid biopsy

Peritoneal carcinomatosis: limits of diagnosis and the case for liquid biopsy

https://doi.org/10.18632/oncotarget.16480

James R.W. McMullen, Matthew Selleck, Nathan R. Wall,  and Maheswari Senthil
43481-43490
Abstract  |  PDF  |  HTML  |  Order a Reprint

Contrast agents in dynamic contrast-enhanced magnetic resonance imaging

Contrast agents in dynamic contrast-enhanced magnetic resonance imaging

https://doi.org/10.18632/oncotarget.16482

Yuling Yan, Xilin Sun,  and Baozhong Shen
43491-43505
Abstract  |  PDF  |  HTML  |  Order a Reprint

The associations between the MAPT polymorphisms and Alzheimer’s disease risk: a meta-analysis

The associations between the MAPT polymorphisms and Alzheimer’s disease risk: a meta-analysis

https://doi.org/10.18632/oncotarget.16490

Futao Zhou,  and Danli Wang
43506-43520
Abstract  |  PDF  |  HTML  |  Order a Reprint

Elevated heparanase expression is associated with poor prognosis in breast cancer: a study based on systematic review and TCGA data

Elevated heparanase expression is associated with poor prognosis in breast cancer: a study based on systematic review and TCGA data

https://doi.org/10.18632/oncotarget.16575

Xu Sun, Ganlin Zhang, Jiayun Nian, Mingwei Yu, Shijian Chen, Yi Zhang, Guowang Yang, Lin Yang, Peiyu Cheng, Chen Yan, Yunfei Ma, Hui Meng, Xiaomin Wang,  and Jin-Ping Li
43521-43535
Abstract  |  PDF  |  HTML  |  Order a Reprint

Revisit 18F-fluorodeoxyglucose oncology positron emission tomography: “systems molecular imaging” of glucose metabolism

Revisit 18F-fluorodeoxyglucose oncology positron emission tomography: “systems molecular imaging” of glucose metabolism

https://doi.org/10.18632/oncotarget.16647

Baozhong Shen, Tao Huang, Yingying Sun, Zhongnan Jin,  and Xiao-Feng Li
43536-43542
Abstract  |  PDF  |  HTML  |  Order a Reprint

Lysophosphatidic acid (LPA) as a pro-fibrotic and pro-oncogenic factor: a pivotal target to improve the radiotherapy therapeutic index

Lysophosphatidic acid (LPA) as a pro-fibrotic and pro-oncogenic factor: a pivotal target to improve the radiotherapy therapeutic index

https://doi.org/10.18632/oncotarget.16672

Chloé Rancoule, Sophie Espenel, Jane-Chloé Trone, Julien Langrand-Escure, Alexis Vallard, Amel Rehailia-Blanchard, Anis El Meddeb Hamrouni, Yaxiong Xia, Jean-Baptiste Guy, Majed Ben-Mrad,  and Nicolas Magné
43543-43554
Abstract  |  PDF  |  HTML  |  Order a Reprint

Breaking the crosstalk of the cellular tumorigenic network: Hypothesis for addressing resistances to targeted therapies in advanced NSCLC

Breaking the crosstalk of the cellular tumorigenic network: Hypothesis for addressing resistances to targeted therapies in advanced NSCLC

https://doi.org/10.18632/oncotarget.16674

Stefan Langhammer,  and Joachim Scheerer
43555-43570
Abstract  |  PDF  |  HTML  |  Order a Reprint

Non-coding RNAs: new biomarkers and therapeutic targets for esophageal cancer

Non-coding RNAs: new biomarkers and therapeutic targets for esophageal cancer

https://doi.org/10.18632/oncotarget.16721

Xiaobin Hou, Jiaxin Wen, Zhipeng Ren,  and Guoliang Zhang
43571-43578
Abstract  |  PDF  |  HTML  |  Order a Reprint

Personalizing Chinese medicine by integrating molecular features of diseases and herb ingredient information: application to acute myeloid leukemia

Personalizing Chinese medicine by integrating molecular features of diseases and herb ingredient information: application to acute myeloid leukemia

https://doi.org/10.18632/oncotarget.16983

Lin Huang, Haichang Li, Duoli Xie, Tieliu Shi,  and Chengping Wen
43579-43591
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Corrections

Correction: The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin

Correction: The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin

https://doi.org/10.18632/oncotarget.18610

José Luis Ordóñez, Ana Teresa Amaral, Angel M. Carcaboso, David Herrero-Martín, María del Carmen García-Macías, Vicky Sevillano, Diego Alonso, Guillem Pascual-Pasto, Laura San-Segundo, Monica Vila-Ubach, Telmo Rodrigues, Susana Fraile, Cristina Teodosio, Agustín Mayo-Iscar, Miguel Aracil, Carlos María Galmarini, Oscar M. Tirado, Jaume Mora,  and Enrique de Álava
43592-43592
Correction  |  PDF

Correction: H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway

Correction: H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway

https://doi.org/10.18632/oncotarget.18611

Shanmin Zhao, Li Li, Shiyong Wang, Chenlin Yu, Bang Xiao, Lifang Lin, Wei Cong, Jishuai Cheng, Wenjing Yang, Wei Sun,  and Shufang Cui
43593-43594
Correction  |  PDF

Retraction

Retraction: The role of CEUS in characterization of superficial lymph nodes: a single center prospective study

Retraction: The role of CEUS in characterization of superficial lymph nodes: a single center prospective study

https://doi.org/10.18632/oncotarget.18637

Giorgio de Stefano, Umberto Scognamiglio, Filomena Di Martino, Roberto Parrella, Francesco Scarano, Giuseppe Signoriello,  and Nunzia Farella
43595-43595
Retraction  |  PDF


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