Oncotarget

Vol 8, No 24

June 13, 2017

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About The Cover

The cover for issue 24 of Oncotarget features Figure 9, "A proposed model for IL-4/IL-13-induced NOX1 expression and colon cell proliferation," by Liu, et al.

Table of Contents

News

The hunt for elusive cancer stem cells

The hunt for elusive cancer stem cells

DOI: 10.18632/oncotarget.17443

Salvatore Condello, Nkechiyere G. Nwani,  and Daniela Matei
38076-38077
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Editorial

MiR210 in neonatal hypoxic-ischemic encephalopathy

MiR210 in neonatal hypoxic-ischemic encephalopathy

DOI: 10.18632/oncotarget.14766

Qingyi Ma,  and Lubo Zhang
38078-38079
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Sales for anti-angiogenic drugs

Sales for anti-angiogenic drugs

DOI: 10.18632/oncotarget.17373

Domenico Ribatti
38080-38081
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Exocytotic pore in a SNARE

Exocytotic pore in a SNARE

DOI: 10.18632/oncotarget.17511

Jernej Jorgačevski, Marko Kreft,  and Robert Zorec
38082-38083
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Priority Research Papers

Retinoblastoma cells activate the AKT pathway and are vulnerable to the PI3K/mTOR inhibitor NVP-BEZ235

Retinoblastoma cells activate the AKT pathway and are vulnerable to the PI3K/mTOR inhibitor NVP-BEZ235

DOI: 10.18632/oncotarget.16970

Chencheng Xie, Matthew J. Freeman, Huarui Lu, Xiaohong Wang, Colleen L. Forster, Aaron L. Sarver,  and Timothy C. Hallstrom
38084-38098
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Lysosomal regulation of cholesterol homeostasis in tuberous sclerosis complex is mediated via NPC1 and LDL-R

Lysosomal regulation of cholesterol homeostasis in tuberous sclerosis complex is mediated via NPC1 and LDL-R

DOI: 10.18632/oncotarget.17485

Harilaos Filippakis, Nicola Alesi, Barbara Ogorek, Julie Nijmeh, Damir Khabibullin, Catherine Gutierrez, Alexander J. Valvezan, James Cunningham, Carmen Priolo,  and Elizabeth P. Henske
38099-38112
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Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells

Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells

DOI: 10.18632/oncotarget.17494

Han Liu, Smitha Antony, Krishnendu Roy, Agnes Juhasz, Yongzhong Wu, Jiamo Lu, Jennifer L. Meitzler, Guojian Jiang, Eric Polley,  and James H. Doroshow
38113-38135
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Research Papers: Gerotarget (Focus on Aging)

Estrogen receptors involvement in intervertebral discogenic pain of the elderly women: colocalization and correlation with the expression of Substance P in nucleus pulposus

Estrogen receptors involvement in intervertebral discogenic pain of the elderly women: colocalization and correlation with the expression of Substance P in nucleus pulposus

DOI: 10.18632/oncotarget.15421

Xiao-Xing Song, Sheng Shi, Zhen Guo, Xin-Feng Li,  and Bu-Wei Yu
38136-38144
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Research Papers: Pathology

Elevated serum level of pancreatic stone protein/regenerating protein (PSP/reg) is observed in diabetic kidney disease

Elevated serum level of pancreatic stone protein/regenerating protein (PSP/reg) is observed in diabetic kidney disease

DOI: 10.18632/oncotarget.16369

Ling Li, Dongyu Jia, Rolf Graf,  and Jiayue Yang
38145-38151
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevated dietary magnesium during pregnancy and postnatal life prevents ectopic mineralization in Enpp1asj mice, a model for generalized arterial calcification of infancy

Elevated dietary magnesium during pregnancy and postnatal life prevents ectopic mineralization in Enpp1asj mice, a model for generalized arterial calcification of infancy

DOI: 10.18632/oncotarget.16687

Joshua Kingman, Jouni Uitto,  and Qiaoli Li
38152-38160
Abstract  |   PDF  |  HTML  |  Order a Reprint

Dietary capsaicin and antibiotics act synergistically to reduce non-alcoholic fatty liver disease induced by high fat diet in mice

Dietary capsaicin and antibiotics act synergistically to reduce non-alcoholic fatty liver disease induced by high fat diet in mice

DOI: 10.18632/oncotarget.16975

Jingjuan Hu, Haihua Luo, Yong Jiang,  and Peng Chen
38161-38175
Abstract  |   PDF  |  HTML  |  Order a Reprint

Mutation of the Sp1 binding site in the 5’ flanking region of SRY causes sex reversal in rabbits

Mutation of the Sp1 binding site in the 5’ flanking region of SRY causes sex reversal in rabbits

DOI: 10.18632/oncotarget.16979

Yuning Song, Tingjun Liu, Yong Wang, Jichao Deng, Mao Chen, Lin Yuan, Yi Lu, Yuxin Xu, Haobin Yao, Zhanjun Li,  and Liangxue Lai
38176-38183
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Alpha-ketoglutarate (AKG) lowers body weight and affects intestinal innate immunity through influencing intestinal microbiota

Alpha-ketoglutarate (AKG) lowers body weight and affects intestinal innate immunity through influencing intestinal microbiota

DOI: 10.18632/oncotarget.17132

Shuai Chen, Peng Bin, Wenkai Ren, Wei Gao, Gang Liu, Jie Yin, Jielin Duan, Yinghui Li, Kang Yao, Ruilin Huang, Bie Tan,  and Yulong Yin
38184-38192
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers: Autophagy and Cell Death

Stroma-derived HGF drives metabolic adaptation of colorectal cancer to angiogenesis inhibitors

Stroma-derived HGF drives metabolic adaptation of colorectal cancer to angiogenesis inhibitors

DOI: 10.18632/oncotarget.16942

Alessia Mira, Virginia Morello, Maria Virtudes Céspedes, Timothy Perera, Paolo M. Comoglio, Ramon Mangues,  and Paolo Michieli
38193-38213
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Methodological Research Paper

Size-dependent penetration of nanoemulsions into epidermis and hair follicles: implications for transdermal delivery and immunization

Size-dependent penetration of nanoemulsions into epidermis and hair follicles: implications for transdermal delivery and immunization

DOI: 10.18632/oncotarget.17130

Rui Su, Wufa Fan, Qin Yu, Xiaochun Dong, Jianping Qi, Quangang Zhu, Weili Zhao, Wei Wu, Zhongjian Chen, Ye Li,  and Yi Lu
38214-38226
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Research Papers

Long noncoding RNA ZFAS1 promotes gastric cancer cells proliferation by epigenetically repressing KLF2 and NKD2 expression

Long noncoding RNA ZFAS1 promotes gastric cancer cells proliferation by epigenetically repressing KLF2 and NKD2 expression

DOI: 10.18632/oncotarget.9611

Fengqi Nie, Xiang Yu, Mingde Huang, Yunfei Wang, Min Xie, Hongwei Ma, Zhaoxia Wang, Wei De,  and Ming Sun
38227-38238
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Selective elimination of long INterspersed element-1 expressing tumour cells by targeted expression of the HSV-TK suicide gene

Selective elimination of long INterspersed element-1 expressing tumour cells by targeted expression of the HSV-TK suicide gene

DOI: 10.18632/oncotarget.16013

Mariam Chendeb, Robert Schneider, Irwin Davidson,  and Anas Fadloun
38239-38250
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Erythropoietin drives breast cancer progression by activation of its receptor EPOR

Erythropoietin drives breast cancer progression by activation of its receptor EPOR

DOI: 10.18632/oncotarget.16368

Ka Kui Chan, Kyle B. Matchett, Jonathan A. Coulter, Hiu-Fung Yuen, Cian M. McCrudden, Shu-Dong Zhang, Gareth W. Irwin, Matthew A. Davidson, Thomas Rülicke, Sophie Schober, Ludger Hengst, Heidelinde Jaekel, Angela Platt-Higgins, Philip S. Rudland, Ken I. Mills, Perry Maxwell, Mohamed El-Tanani,  and Terence R. Lappin
38251-38263
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Lipid degradation promotes prostate cancer cell survival

Lipid degradation promotes prostate cancer cell survival

DOI: 10.18632/oncotarget.16123

Harri M. Itkonen, Michael Brown, Alfonso Urbanucci, Gregory Tredwell, Chung Ho Lau, Stefan Barfeld, Claire Hart, Ingrid J. Guldvik, Mandeep Takhar, Hannelore V. Heemers, Nicholas Erho, Katarzyna Bloch, Elai Davicioni, Rita Derua, Etienne Waelkens, James L. Mohler, Noel Clarke, Johan V. Swinnen, Hector C. Keun, Ole P. Rekvig,  and Ian G. Mills
38264-38275
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumor-reducing effect of the clinically used drug clofazimine in a SCID mouse model of pancreatic ductal adenocarcinoma

Tumor-reducing effect of the clinically used drug clofazimine in a SCID mouse model of pancreatic ductal adenocarcinoma

DOI: 10.18632/oncotarget.11299

Angela Zaccagnino, Antonella Managò, Luigi Leanza, Artur Gontarewitz, Bernhard Linder, Michele Azzolini, Lucia Biasutto, Mario Zoratti, Roberta Peruzzo, Karen Legler, Anna Trauzold, Holger Kalthoff,  and Ildiko Szabo
38276-38293
Abstract  |    |  PDF  |  HTML  |  Order a Reprint

CD24 Expression and differential resistance to chemotherapy in triple-negative breast cancer

CD24 Expression and differential resistance to chemotherapy in triple-negative breast cancer

DOI: 10.18632/oncotarget.16203

Xinyu Deng, Sophia Apple, Hong Zhao, Jeongyoon Song, Minna Lee, William Luo, Xiancheng Wu, Debra Chung, Richard J. Pietras,  and Helena R. Chang
38294-38308
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Stable aneuploid tumors cells are more sensitive to TTK inhibition than chromosomally unstable cell lines

Stable aneuploid tumors cells are more sensitive to TTK inhibition than chromosomally unstable cell lines

DOI: 10.18632/oncotarget.16213

Marion A.A. Libouban, Jeroen A.D.M. de Roos, Joost C.M. Uitdehaag, Nicole Willemsen-Seegers, Sara Mainardi, Jelle Dylus, Jos de Man, Bastiaan Tops, Jules P.P. Meijerink, Zuzana Storchová, Rogier C. Buijsman, René H. Medema,  and Guido J.R. Zaman
38309-38325
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Loss of tumour-specific ATM protein expression is an independent prognostic factor in early resected NSCLC

Loss of tumour-specific ATM protein expression is an independent prognostic factor in early resected NSCLC

DOI: 10.18632/oncotarget.16215

Lars F. Petersen, Alexander C. Klimowicz, Shannon Otsuka, Anifat A. Elegbede, Stephanie K. Petrillo, Tyler Williamson, Chris T. Williamson, Mie Konno, Susan P. Lees-Miller, Desiree Hao, Don Morris, Anthony M. Magliocco,  and D. Gwyn Bebb
38326-38336
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Development of [11C]vemurafenib employing a carbon-11 carbonylative Stille coupling and preliminary evaluation in mice bearing melanoma tumor xenografts

Development of [11C]vemurafenib employing a carbon-11 carbonylative Stille coupling and preliminary evaluation in mice bearing melanoma tumor xenografts

DOI: 10.18632/oncotarget.16321

Paul Slobbe, Albert D. Windhorst, Kevin Adamzek, Marije Bolijn, Robert C. Schuit, Daniëlle A.M. Heideman, Guus A.M.S. van Dongen,  and Alex J. Poot
38337-38350
Abstract  |   PDF  |  HTML  |  Order a Reprint

Histone hypoacetylation contributes to CXCL12 downregulation in colon cancer: impact on tumor growth and cell migration

Histone hypoacetylation contributes to CXCL12 downregulation in colon cancer: impact on tumor growth and cell migration

DOI: 10.18632/oncotarget.16323

Benoît Romain, Radhia Benbrika-Nehmar, Laetitia Marisa, Michèle Legrain, Viviane Lobstein, Attila Oravecz, Laetitia Poidevin, Cyril Bour, Jean-Noël Freund, Isabelle Duluc, Dominique Guenot,  and Erwan Pencreach
38351-38366
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The associations of genetic polymorphisms in CYP1A2 and CYP3A4 with clinical outcomes of breast cancer patients in northern China

The associations of genetic polymorphisms in CYP1A2 and CYP3A4 with clinical outcomes of breast cancer patients in northern China

DOI: 10.18632/oncotarget.16359

Xianan Bai, Jingjing Xie, Shanshan Sun, Xianyu Zhang, Yongdong Jiang,  and Da Pang
38367-38377
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Accumulation of myeloid-derived suppressor cells (MDSCs) induced by low levels of IL-6 correlates with poor prognosis in bladder cancer

Accumulation of myeloid-derived suppressor cells (MDSCs) induced by low levels of IL-6 correlates with poor prognosis in bladder cancer

DOI: 10.18632/oncotarget.16386

Guoliang Yang, Wenyan Shen, Yan Zhang, Mengyao Liu, Lianhua Zhang, Qiang Liu, Hui Hui Lu,  and Juanjie Bo
38378-38388
Abstract  |   PDF  |  HTML  |  Order a Reprint

Complementary utility of targeted next-generation sequencing and immunohistochemistry panels as a screening platform to select targeted therapy for advanced gastric cancer

Complementary utility of targeted next-generation sequencing and immunohistochemistry panels as a screening platform to select targeted therapy for advanced gastric cancer

DOI: 10.18632/oncotarget.16409

Hyo Song Kim, Hanna Lee, Su-Jin Shin, Seung-Hoon Beom, Minkyu Jung, Sujin Bae, Eun Young Lee, Kyu Hyun Park, Yoon Young Choi, Taeil Son, Hyoung-Il Kim, Jae-Ho Cheong, Woo Jin Hyung, Jun Chul Park, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee, Woong Sub Koom, Joon Seok Lim, Hyun Cheol Chung, Sung Hoon Noh, Sun Young Rha, Hyunki Kim,  and Soonmyung Paik
38389-38398
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Interaction of Epstein-Barr virus genes with human gastric carcinoma transcriptome

Interaction of Epstein-Barr virus genes with human gastric carcinoma transcriptome

DOI: 10.18632/oncotarget.16417

Ruiyuan Zhang, Michael J. Strong, Melody Baddoo, Zhen Lin, Yu-Ping Wang, Erik K. Flemington,  and Yao-Zhong Liu
38399-38412
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The value of MRI in evaluating the efficacy and complications with the treatment of intra-arterial chemotherapy for retinoblastoma

The value of MRI in evaluating the efficacy and complications with the treatment of intra-arterial chemotherapy for retinoblastoma

DOI: 10.18632/oncotarget.16423

Shuxian Chen, Xunda Ji, Ming Liu, Zhengrong Xia, Hui Zheng, Qiufeng Yin, He Wang,  and Yuhua Li
38413-38425
Abstract  |   PDF  |  HTML  |  Order a Reprint

TAZ induces lung cancer stem cell properties and tumorigenesis by up-regulating ALDH1A1

TAZ induces lung cancer stem cell properties and tumorigenesis by up-regulating ALDH1A1

DOI: 10.18632/oncotarget.16430

Jihang Yu, Adel Alharbi, Hongchao Shan, Yawei Hao, Brooke Snetsinger, Michael J. Rauh,  and Xiaolong Yang
38426-38443
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Effects of AQP5 gene silencing on proliferation, migration and apoptosis of human glioma cells through regulating EGFR/ERK/ p38 MAPK signaling pathway

Effects of AQP5 gene silencing on proliferation, migration and apoptosis of human glioma cells through regulating EGFR/ERK/ p38 MAPK signaling pathway

DOI: 10.18632/oncotarget.16461

Jian Yang, Jian-Nan Zhang, Wei-Lin Chen, Gui-Song Wang, Qing Mao, Shan-Quan Li, Wen-Hao Xiong, Ying-Ying Lin, Jian-Wei Ge, Xiao-Xiong Li, Zhao Gu,  and Chun-Run Zhao
38444-38455
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genotype-phenotype correlations in Chinese von Hippel–Lindau disease patients

Genotype-phenotype correlations in Chinese von Hippel–Lindau disease patients

DOI: 10.18632/oncotarget.16594

Shuanghe Peng, Matthew J. Shepard, Jiangyi Wang, Teng Li, Xianghui Ning, Lin Cai, Zhengping Zhuang,  and Kan Gong
38456-38465
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Synthesis, bioactivity, 3D-QSAR studies of novel dibenzofuran derivatives as PTP-MEG2 inhibitors

Synthesis, bioactivity, 3D-QSAR studies of novel dibenzofuran derivatives as PTP-MEG2 inhibitors

DOI: 10.18632/oncotarget.16595

Ying Ma, Hui-Yu Wei, Yu-Ze Zhang, Wen-Yan Jin, Hong-Lian Li, Hui Zhou, Xian-Chao Cheng,  and Run-Ling Wang
38466-38481
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Apocynin attenuates left ventricular remodeling in diabetic rabbits

Apocynin attenuates left ventricular remodeling in diabetic rabbits

DOI: 10.18632/oncotarget.16599

Jiuchun Qiu, Jianping Zhao, Jian Li, Xue Liang, Yajuan Yang, Zhiwei Zhang, Xiaowei Zhang, Huaying Fu, Panagiotis Korantzopoulos, Gary Tse, Tong Liu,  and Guangping Li
38482-38490
Abstract  |   PDF  |  HTML  |  Order a Reprint

The value of FATS expression in predicting sensitivity to radiotherapy in breast cancer

The value of FATS expression in predicting sensitivity to radiotherapy in breast cancer

DOI: 10.18632/oncotarget.16630

Jun Zhang, Nan Wu, Tiemei Zhang, Tao Sun, Yi Su, Jing Zhao, Kun Mu, Zhao Jin, Ming Gao, Juntian Liu,  and Lin Gu
38491-38500
Abstract  |   PDF  |  HTML  |  Order a Reprint

Early detection of gastric cancer using global, genome-wide and IRF4, ELMO1, CLIP4 and MSC DNA methylation in endoscopic biopsies

Early detection of gastric cancer using global, genome-wide and IRF4, ELMO1, CLIP4 and MSC DNA methylation in endoscopic biopsies

DOI: 10.18632/oncotarget.16258

Francesca Pirini, Sassan Noazin, Martha H. Jahuira-Arias, Sebastian Rodriguez-Torres, Leah Friess, Christina Michailidi, Jaime Cok, Juan Combe, Gloria Vargas, William Prado, Ethan Soudry, Jimena Pérez, Tikki Yudin, Andrea Mancinelli, Helen Unger, Carmen Ili-Gangas, Priscilla Brebi-Mieville, Douglas E. Berg, Masamichi Hayashi, David Sidransky, Robert H. Gilman,  and Rafael Guerrero-Preston
38501-38516
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of urine biomarkers associated with lung adenocarcinoma

Identification of urine biomarkers associated with lung adenocarcinoma

DOI: 10.18632/oncotarget.15870

Weiwei Wang, Shanshan Wang,  and Man Zhang
38517-38529
Abstract  |   PDF  |  HTML  |  Order a Reprint

CYP genes in osteosarcoma: Their role in tumorigenesis, pulmonary metastatic microenvironment and treatment response

CYP genes in osteosarcoma: Their role in tumorigenesis, pulmonary metastatic microenvironment and treatment response

DOI: 10.18632/oncotarget.15869

Alini Trujillo-Paolillo, Francine Tesser-Gamba, Antonio Sergio Petrilli, Maria Teresa de Seixas Alves, Reinaldo Jesus Garcia Filho, Renato de Oliveira,  and Silvia Regina Caminada de Toledo
38530-38540
Abstract  |    |  PDF  |  HTML  |  Order a Reprint

Metabolomics uncovers a link between inositol metabolism and osteosarcoma metastasis

Metabolomics uncovers a link between inositol metabolism and osteosarcoma metastasis

DOI: 10.18632/oncotarget.15872

Ling Ren, Ellen S. Hong, Arnulfo Mendoza, Sameer Issaq, Christine Tran Hoang, Michael Lizardo, Amy LeBlanc,  and Chand Khanna
38541-38553
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Laminarin promotes anti-cancer immunity by the maturation of dendritic cells

Laminarin promotes anti-cancer immunity by the maturation of dendritic cells

DOI: 10.18632/oncotarget.16170

Kyeongeun Song, Li Xu, Wei Zhang, Yun Cai, Bian Jang, Junghwan Oh,  and Jun-O Jin
38554-38567
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Novel recombinant immunotoxin of EGFR specific nanobody fused with cucurmosin, construction and antitumor efficiency in vitro

Novel recombinant immunotoxin of EGFR specific nanobody fused with cucurmosin, construction and antitumor efficiency in vitro

DOI: 10.18632/oncotarget.16930

Cuimin Deng, Jiani Xiong, Xiaofan Gu, Xiaoying Chen, Shuifa Wu, Zhe Wang, Duanduan Wang, Jinjin Tu,  and Jieming Xie
38568-38580
Abstract  |   PDF  |  HTML  |  Order a Reprint

Selective eradication of cancer cells by delivery of adenovirus-based toxins

Selective eradication of cancer cells by delivery of adenovirus-based toxins

DOI: 10.18632/oncotarget.16934

Shiran Shapira, Assaf Shapira, Diana Kazanov, Gil Hevroni, Sarah Kraus,  and Nadir Arber
38581-38591
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Multiplexed gene expression profiling identifies the FGFR4 pathway as a novel biomarker in intrahepatic cholangiocarcinoma

Multiplexed gene expression profiling identifies the FGFR4 pathway as a novel biomarker in intrahepatic cholangiocarcinoma

DOI: 10.18632/oncotarget.16951

Changhoon Yoo, Jihoon Kang, Deokhoon Kim, Kyu-Pyo Kim, Baek-Yeol Ryoo, Seung-Mo Hong, Jung Jin Hwang, Seong-Yun Jeong, Shin Hwang, Ki-Hun Kim, Young-Joo Lee, Klaus P. Hoeflich, Oleg Schmidt-Kittler, Stephen Miller,  and Eun Kyung Choi
38592-38601
Abstract  |   PDF  |  HTML  |  Order a Reprint

Effects of TLR-2/NF-κB signaling pathway on the occurrence of degenerative knee osteoarthritis: an in vivo and in vitro study

Effects of TLR-2/NF-κB signaling pathway on the occurrence of degenerative knee osteoarthritis: an in vivo and in vitro study

DOI: 10.18632/oncotarget.16199

Yi-Xun Liu, Guo-Dong Wang, Xiao Wang, Yong-Le Zhang,  and Tian-Lun Zhang
38602-38617
Abstract  |    |  PDF  |  HTML  |  Order a Reprint

The impact of receptor recycling on the exocytosis of αvβ3 integrin targeted gold nanoparticles

The impact of receptor recycling on the exocytosis of αvβ3 integrin targeted gold nanoparticles

DOI: 10.18632/oncotarget.16955

Yanan Cui, Xiaoning Song, Suxin Li, Bing He, Lan Yuan, Wenbing Dai, Hua Zhang, Xueqing Wang, Bin Yang,  and Qiang Zhang
38618-38630
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Quercetin delays postovulatory aging of mouse oocytes by regulating SIRT expression and MPF activity

Quercetin delays postovulatory aging of mouse oocytes by regulating SIRT expression and MPF activity

DOI: 10.18632/oncotarget.16219

HaiYang Wang, Yu-Jin Jo, Jeong Su Oh,  and Nam-Hyung Kim
38631-38641
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A mathematical theory of the transcription repression (TR) therapy of cancer - whether and how it may work

A mathematical theory of the transcription repression (TR) therapy of cancer - whether and how it may work

DOI: 10.18632/oncotarget.16957

Yuxin Chen, Haijun Wen,  and Chung-I Wu
38642-38649
Abstract  |   PDF  |  HTML  |  Order a Reprint

Low-density lipoprotein receptor-related protein 6 is a novel coreceptor of protease-activated receptor-2 in the dynamics of cancer-associated β-catenin stabilization

Low-density lipoprotein receptor-related protein 6 is a novel coreceptor of protease-activated receptor-2 in the dynamics of cancer-associated β-catenin stabilization

DOI: 10.18632/oncotarget.16246

Jeetendra Kumar Nag, Arun Kancharla, Myriam Maoz, Hagit Turm, Daniel Agranovich, Cheddi Lal Gupta, Beatrice Uziely,  and Rachel Bar-Shavit
38650-38667
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RNA sequencing-based cell proliferation analysis across 19 cancers identifies a subset of proliferation-informative cancers with a common survival signature

RNA sequencing-based cell proliferation analysis across 19 cancers identifies a subset of proliferation-informative cancers with a common survival signature

DOI: 10.18632/oncotarget.16961

Ryne C. Ramaker, Brittany N. Lasseigne, Andrew A. Hardigan, Laura Palacio, David S. Gunther, Richard M. Myers,  and Sara J. Cooper
38668-38681
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Is there a prognostic value of tumor location among Chinese patients with colorectal cancer?

Is there a prognostic value of tumor location among Chinese patients with colorectal cancer?

DOI: 10.18632/oncotarget.16305

Fangqi Liu, Cong Li, Huixun Jia, Li Yang, Yuchen Wu, Jiang Zhao, Sanjun Cai, Ji Zhu,  and Ye Xu
38682-38692
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The TERT rs2736100 polymorphism increases cancer risk: A meta-analysis

The TERT rs2736100 polymorphism increases cancer risk: A meta-analysis

DOI: 10.18632/oncotarget.16309

Hui Li, Yanyan Xu, Hua Mei, Liang Peng, Xiaojie Li,  and Jianzhou Tang
38693-38705
Abstract  |    |  PDF  |  HTML  |  Order a Reprint

Distribution patterns of 21-gene recurrence score in 980 Chinese estrogen receptor-positive, HER2-negative early breast cancer patients

Distribution patterns of 21-gene recurrence score in 980 Chinese estrogen receptor-positive, HER2-negative early breast cancer patients

DOI: 10.18632/oncotarget.16313

Jiayi Wu, Yan Fang, Lin Lin, Xiaochun Fei, Weiqi Gao, Siji Zhu, Yu Zong, Xiaosong Chen, Ou Huang, Jian-Rong He, Li Zhu, Weiguo Chen, Yafen Li,  and Kunwei Shen
38706-38716
Abstract  |   PDF  |  HTML  |  Order a Reprint

Contributions of MET activation to BCR-ABL1 tyrosine kinase inhibitor resistance in chronic myeloid leukemia cells

Contributions of MET activation to BCR-ABL1 tyrosine kinase inhibitor resistance in chronic myeloid leukemia cells

DOI: 10.18632/oncotarget.16314

Masanobu Tsubaki, Tomoya Takeda, Toshiki Kino, Kazuko Sakai, Tatsuki Itoh, Motohiro Imano, Takashi Nakayama, Kazuto Nishio, Takao Satou,  and Shozo Nishida
38717-38730
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Downregulation of Bmi1 in breast cancer stem cells suppresses tumor growth and proliferation

Downregulation of Bmi1 in breast cancer stem cells suppresses tumor growth and proliferation

DOI: 10.18632/oncotarget.16317

Mathangi Srinivasan, Dhruba J. Bharali, Thangirala Sudha, Maha Khedr, Ian Guest, Stewart Sell, Gennadi V. Glinsky,  and Shaker A. Mousa
38731-38742
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Krüppel-like factor 17 inhibits urokinase plasminogen activator gene expression to suppress cell invasion through the Src/p38/MAPK signaling pathway in human lung adenocarcinoma

Krüppel-like factor 17 inhibits urokinase plasminogen activator gene expression to suppress cell invasion through the Src/p38/MAPK signaling pathway in human lung adenocarcinoma

DOI: 10.18632/oncotarget.17020

Xing-Dong Cai, Li Che, Jia-Xin Lin, Shuai Huang, Jiong Li, Xiao-Yan Liu, Xing-Fei Pan, Qin-Qin Wang, Li Chen, Ming-Juan Lin, Zhi-Hong Huang, Hong-Ming Ma, Yi Wu, Sheng-Ming Liu,  and Yan-Bin Zhou
38743-38754
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Significance of PI3K/AKT signaling pathway in metastasis of esophageal squamous cell carcinoma and its potential as a target for anti-metastasis therapy

Significance of PI3K/AKT signaling pathway in metastasis of esophageal squamous cell carcinoma and its potential as a target for anti-metastasis therapy

DOI: 10.18632/oncotarget.16333

Bin Li, Wen Wen Xu, Alfred King Y. Lam, Yang Wang, Hui-Fang Hu, Xin Yuan Guan, Yan Ru Qin, Nassim Saremi, Sai Wah Tsao, Qing-Yu He,  and Annie L.M. Cheung
38755-38766
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Estrogen enhances mismatch repair by induction of MLH1 expression via estrogen receptor-β

Estrogen enhances mismatch repair by induction of MLH1 expression via estrogen receptor-β

DOI: 10.18632/oncotarget.16351

Jun-Yu Lu, Peng Jin, Wei Gao, De-Zhi Wang,  and Jian-Qiu Sheng
38767-38779
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A consensus-hemagglutinin-based vaccine delivered by an attenuated Salmonella mutant protects chickens against heterologous H7N1 influenza virus

A consensus-hemagglutinin-based vaccine delivered by an attenuated Salmonella mutant protects chickens against heterologous H7N1 influenza virus

DOI: 10.18632/oncotarget.16353

Kim Je Hyoung, Irshad Ahmed Hajam,  and John Hwa Lee
38780-38792
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Early effective treatment of small pulmonary nodules with video-assisted thoracoscopic surgery combined with CT-guided dual-barbed hookwire localization

Early effective treatment of small pulmonary nodules with video-assisted thoracoscopic surgery combined with CT-guided dual-barbed hookwire localization

DOI: 10.18632/oncotarget.17044

Han Qi, Chao Wan, Liang Zhang, Junye Wang, Ze Song, Rong Zhang, Zhenfeng Zhang,  and Weijun Fan
38793-38801
Abstract  |   PDF  |  HTML  |  Order a Reprint

Metabolite marker discovery for the detection of bladder cancer by comparative metabolomics

Metabolite marker discovery for the detection of bladder cancer by comparative metabolomics

DOI: 10.18632/oncotarget.16393

Chi-Hung Shao, Chien-Lun Chen, Jia-You Lin, Chao-Jung Chen, Shu-Hsuan Fu, Yi-Ting Chen, Yu-Sun Chang, Jau-Song Yu, Ke-Hung Tsui, Chiun-Gung Juo,  and Kun-Pin Wu
38802-38810
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Smad inhibitor induces CSC differentiation for effective chemosensitization in cyclin D1- and TGF-β/Smad-regulated liver cancer stem cell-like cells

Smad inhibitor induces CSC differentiation for effective chemosensitization in cyclin D1- and TGF-β/Smad-regulated liver cancer stem cell-like cells

DOI: 10.18632/oncotarget.16402

Wei Xia, Chung Mau Lo, Randy Y.C. Poon, Tan To Cheung, Albert C.Y. Chan, Lin Chen, Sitian Yang, George S.W. Tsao,  and Xiao Qi Wang
38811-38824
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MTA1 promotes epithelial to mesenchymal transition and metastasis in non-small-cell lung cancer

MTA1 promotes epithelial to mesenchymal transition and metastasis in non-small-cell lung cancer

DOI: 10.18632/oncotarget.16404

Ke Ma, Yangwei Fan, Xuyuan Dong, Danfeng Dong, Yuyan Guo, Xin Wei, Jing Ning, Qianqian Geng, Chuying Wang, Yuan Hu, Mengya Li, Wenxia Niu, Enxiao Li,  and Yinying Wu
38825-38840
Abstract  |    |  PDF  |  HTML  |  Order a Reprint

Expression of guanylyl cyclase C in tissue samples and the circulation of rectal cancer patients

Expression of guanylyl cyclase C in tissue samples and the circulation of rectal cancer patients

DOI: 10.18632/oncotarget.16406

Yong Liu, Guoping Cheng, Jun Qian, HaiXing Ju, YuPing Zhu, Meucci Stefano, Ulrich Keilholz,  and DeChuan Li
38841-38849
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The PD-1, PD-L1 expression and CD3+ T cell infiltration in relation to outcome in advanced gastric signet-ring cell carcinoma, representing a potential biomarker for immunotherapy

The PD-1, PD-L1 expression and CD3+ T cell infiltration in relation to outcome in advanced gastric signet-ring cell carcinoma, representing a potential biomarker for immunotherapy

DOI: 10.18632/oncotarget.16407

Shenying Jin, Bo Xu, Lixia Yu, Yao Fu, Hongyan Wu, Xiangshan Fan, Jia Wei,  and Baorui Liu
38850-38862
Abstract  |   PDF  |  HTML  |  Order a Reprint

ZNF452 facilitates tumor proliferation and invasion via activating AKT-GSK3β signaling pathway and predicts poor prognosis of non-small cell lung cancer patients

ZNF452 facilitates tumor proliferation and invasion via activating AKT-GSK3β signaling pathway and predicts poor prognosis of non-small cell lung cancer patients

DOI: 10.18632/oncotarget.16408

Xiupeng Zhang, Haijing Zhou, Yong Zhang, Lin Cai, Guiyang Jiang, Ailin Li, Yuan Miao, Qingchang Li, Xueshan Qiu,  and Enhua Wang
38863-38875
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Contribution of macrophages in the contrast loss in iron oxide-based MRI cancer cell tracking studies

Contribution of macrophages in the contrast loss in iron oxide-based MRI cancer cell tracking studies

DOI: 10.18632/oncotarget.17103

Pierre Danhier, Gladys Deumer, Nicolas Joudiou, Caroline Bouzin, Philippe Levêque, Vincent Haufroid, Bénédicte F. Jordan, Olivier Feron, Pierre Sonveaux,  and Bernard Gallez
38876-38885
Abstract  |   PDF  |  HTML  |  Order a Reprint

Syntenin promotes VEGF-induced VEGFR2 endocytosis and angiogenesis by increasing ephrin-B2 function in endothelial cells

Syntenin promotes VEGF-induced VEGFR2 endocytosis and angiogenesis by increasing ephrin-B2 function in endothelial cells

DOI: 10.18632/oncotarget.16452

Nara Tae, Suhyun Lee, Okwha Kim, Juhee Park, Sunghun Na,  and Jeong-Hyung Lee
38886-38901
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A 3-miRNA signature predicts prognosis of pediatric and adolescent cytogenetically normal acute myeloid leukemia

A 3-miRNA signature predicts prognosis of pediatric and adolescent cytogenetically normal acute myeloid leukemia

DOI: 10.18632/oncotarget.17151

Ruiqi Zhu, Weiwei Zhao, Fengjuan Fan, Liang Tang, Jingdi Liu, Ting Luo, Jun Deng,  and Yu Hu
38902-38913
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevated serum A20 is associated with severity of chronic hepatitis B and A20 inhibits NF-κB-mediated inflammatory response

Elevated serum A20 is associated with severity of chronic hepatitis B and A20 inhibits NF-κB-mediated inflammatory response

DOI: 10.18632/oncotarget.17153

Hanchen Xu, Lei Wang, Peiyong Zheng, Yang Liu, Chunlei Zhang, Kaiping Jiang, Haiyan Song,  and Guang Ji
38914-38926
Abstract  |   PDF  |  HTML  |  Order a Reprint

PEGylated PLGA-based phase shift nanodroplets combined with focused ultrasound for blood brain barrier opening in rats

PEGylated PLGA-based phase shift nanodroplets combined with focused ultrasound for blood brain barrier opening in rats

DOI: 10.18632/oncotarget.17155

Xiang Zhang, Jiangang Hu, Guanjian Zhao, Ning Huang, Ying Tan, Li Pi, Qing Huang, Feng Wang, Zhigang Wang, Zhibiao Wang,  and Yuan Cheng
38927-38936
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

DDX23-Linc00630-HDAC1 axis activates the Notch pathway to promote metastasis

DDX23-Linc00630-HDAC1 axis activates the Notch pathway to promote metastasis

DOI: 10.18632/oncotarget.17156

Guozhang Mao, Hui Jin,  and Liuguang Wu
38937-38949
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of eight genetic variants as novel determinants of dyslipidemia in Japanese by exome-wide association studies

Identification of eight genetic variants as novel determinants of dyslipidemia in Japanese by exome-wide association studies

DOI: 10.18632/oncotarget.17159

Yoshiji Yamada, Jun Sakuma, Ichiro Takeuchi, Yoshiki Yasukochi, Kimihiko Kato, Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Masaaki Muramatsu, Motoji Sawabe, Yoshinori Fujiwara, Yu Taniguchi, Shuichi Obuchi, Hisashi Kawai, Shoji Shinkai, Seijiro Mori, Tomio Arai,  and Masashi Tanaka
38950-38961
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression pattern of estroprogestinic receptors in sinonasal inverted papilloma

Expression pattern of estroprogestinic receptors in sinonasal inverted papilloma

DOI: 10.18632/oncotarget.17161

Agostino Serra, Rosario Caltabiano, Giacomo Spinato, Salvatore Gallina, Salvatore Caruso, Venerando Rapisarda, Paola Di Mauro, Veronica Castro, Angelo Conti, Luisa Licciardello, Luigi Maiolino, Salvatore Lanzafame,  and Salvatore Cocuzza
38962-38968
Abstract  |   PDF  |  HTML  |  Order a Reprint

Prognostic value of IRF-2 expression in colorectal cancer

Prognostic value of IRF-2 expression in colorectal cancer

DOI: 10.18632/oncotarget.17163

Zubing Mei, Guanghui Wang, Zhonglin Liang, Ang Cui, Andong Xu, Yun Liu, Chenying Liu, Yili Yang,  and Long Cui
38969-38977
Abstract  |   PDF  |  HTML  |  Order a Reprint

Pelvic reconstruction with different rod-screw systems following Enneking type I/I + IV resection: a clinical study

Pelvic reconstruction with different rod-screw systems following Enneking type I/I + IV resection: a clinical study

DOI: 10.18632/oncotarget.17164

Peng Lin, Youyou Shao, Huigen Lu, Zhengliang Zhang, Haiqing Lin, Shengdong Wang, Binghao Li, Hengyuan Li, Zhan Wang, Nong Lin,  and Zhaoming Ye
38978-38989
Abstract  |   PDF  |  HTML  |  Order a Reprint

Antineoplastic effects of CPPTL via the ROS/JNK pathway in acute myeloid leukemia

Antineoplastic effects of CPPTL via the ROS/JNK pathway in acute myeloid leukemia

DOI: 10.18632/oncotarget.17166

Hui-Er Gao, Yue Sun, Ya-Hui Ding, Jing Long, Xiao-Lei Liu, Ming Yang, Qing Ji, Ying-Hui Li, Yue Chen, Quan Zhang,  and Ying-Dai Gao
38990-39000
Abstract  |   PDF  |  HTML  |  Order a Reprint

Co-expression of AFAP1-AS1 and PD-1 predicts poor prognosis in nasopharyngeal carcinoma

Co-expression of AFAP1-AS1 and PD-1 predicts poor prognosis in nasopharyngeal carcinoma

DOI: 10.18632/oncotarget.16545

Yanyan Tang, Yi He, Lei Shi, Liting Yang, Jinpeng Wang, Yu Lian, Chunmei Fan, Ping Zhang, Can Guo, Shanshan Zhang, Zhaojian Gong, Xiayu Li, Fang Xiong, Xiaoling Li, Yong Li, Guiyuan Li, Wei Xiong,  and Zhaoyang Zeng
39001-39011
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Abce1 orchestrates M-phase entry and cytoskeleton architecture in mouse oocyte

Abce1 orchestrates M-phase entry and cytoskeleton architecture in mouse oocyte

DOI: 10.18632/oncotarget.16546

Xiao-Fei Jiao, Chun-Jie Huang, Di Wu, Jia-Yu Zhang, Yu-Ting Long, Fan Chen, Xiang Li,  and Li-Jun Huo
39012-39020
Abstract  |    |  PDF  |  HTML  |  Order a Reprint

CD47 promotes ovarian cancer progression by inhibiting macrophage phagocytosis

CD47 promotes ovarian cancer progression by inhibiting macrophage phagocytosis

DOI: 10.18632/oncotarget.16547

Ran Liu, Huiting Wei, Peng Gao, Hu Yu, Ke Wang, Zheng Fu, Baohui Ju, Meng Zhao, Shangwen Dong, Zhijun Li, Yifeng He, Yuting Huang,  and Zhi Yao
39021-39032
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Wnt5a and CCL25 promote adult T-cell acute lymphoblastic leukemia cell migration, invasion and metastasis

Wnt5a and CCL25 promote adult T-cell acute lymphoblastic leukemia cell migration, invasion and metastasis

DOI: 10.18632/oncotarget.16559

Xinzhou Deng, Zhenbo Tu, Meng Xiong, Kingsley Tembo, Lu Zhou, Pan Liu, Shan Pan, Jie Xiong, Xiangyong Yang, Jun Leng, Qian Zhang, Ruijing Xiao,  and Qiuping Zhang
39033-39047
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CBX7 negatively regulates migration and invasion in glioma via Wnt/β-catenin pathway inactivation

CBX7 negatively regulates migration and invasion in glioma via Wnt/β-catenin pathway inactivation

DOI: 10.18632/oncotarget.16587

Zhongyuan Bao, Xiupeng Xu, Yinlong Liu, Honglu Chao, Chao Lin, Zheng Li, Yongping You, Ning Liu,  and Jing Ji
39048-39063
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Antiproliferative effect of ZSTK474 alone or in combination with chemotherapeutic drugs on HL60 and HL60/ADR cells

Antiproliferative effect of ZSTK474 alone or in combination with chemotherapeutic drugs on HL60 and HL60/ADR cells

DOI: 10.18632/oncotarget.16589

Qianxiang Zhou, Yali Chen, Lei Zhang, Yuxu Zhong, Zhe Zhang, Ran Wang, Meihua Jin, Min Gong, Yuling Qiu,  and Dexin Kong
39064-39076
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prokaryotic expression of MLAA-34 and generation of a novel human ScFv against MLAA-34 by phage display technology

Prokaryotic expression of MLAA-34 and generation of a novel human ScFv against MLAA-34 by phage display technology

DOI: 10.18632/oncotarget.16590

Yang Zhang, Pengyu Zhang, Aili He, Yun Yang, Jianli Wang, Hui Zhang,  and Wanggang Zhang
39077-39086
Abstract  |    |  PDF  |  HTML  |  Order a Reprint

Cytochrome P450 1B1 inhibition suppresses tumorigenicity of prostate cancer via caspase-1 activation

Cytochrome P450 1B1 inhibition suppresses tumorigenicity of prostate cancer via caspase-1 activation

DOI: 10.18632/oncotarget.16598

Inik Chang, Yozo Mitsui, Seul Ki Kim, Ji Su Sun, Hye Sook Jeon, Jung Yun Kang, Nam Ju Kang, Shinichiro Fukuhara, Ankurpreet Gill, Varahram Shahryari, Z. Laura Tabatabai, Kirsten L. Greene, Rajvir Dahiya, Dong Min Shin,  and Yuichiro Tanaka
39087-39100
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel RON splice variant lacking exon 2 activates the PI3K/AKT pathway via PTEN phosphorylation in colorectal carcinoma cells

A novel RON splice variant lacking exon 2 activates the PI3K/AKT pathway via PTEN phosphorylation in colorectal carcinoma cells

DOI: 10.18632/oncotarget.16603

Yu Ling, Yeye Kuang, Lin-Lin Chen, Wei-Feng Lao, Yao-Ru Zhu, Le-Qi Wang,  and Da Wang
39101-39116
Abstract  |    |  PDF  |  HTML  |  Order a Reprint

Combination GITR targeting/PD-1 blockade with vaccination drives robust antigen-specific antitumor immunity

Combination GITR targeting/PD-1 blockade with vaccination drives robust antigen-specific antitumor immunity

DOI: 10.18632/oncotarget.16605

Daniel O. Villarreal, Diana Chin, Melissa A. Smith, Leopoldo L. Luistro,  and Linda A. Snyder
39117-39130
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cofilin 1 induces the epithelial-mesenchymal transition of gastric cancer cells by promoting cytoskeletal rearrangement

Cofilin 1 induces the epithelial-mesenchymal transition of gastric cancer cells by promoting cytoskeletal rearrangement

DOI: 10.18632/oncotarget.16608

Haibo Wang, Lide Tao, Feng Jin, Hao Gu, Xiaojun Dai, Tengyang Ni, Jun Feng, Yanbing Ding, Weiming Xiao, Yayun Qian,  and Yanqing Liu
39131-39142
Abstract  |   PDF  |  HTML  |  Order a Reprint

Proton pump inhibitor ilaprazole suppresses cancer growth by targeting T-cell-originated protein kinase

Proton pump inhibitor ilaprazole suppresses cancer growth by targeting T-cell-originated protein kinase

DOI: 10.18632/oncotarget.16609

Mengzhu Zheng, Shanshan Luan, Suyu Gao, Li Cheng, Bin Hao, Jiacheng Li, Yao Chen, Xuemei Hou, Lixia Chen,  and Hua Li
39143-39153
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IL-6R/STAT3/miR-204 feedback loop contributes to cisplatin resistance of epithelial ovarian cancer cells

IL-6R/STAT3/miR-204 feedback loop contributes to cisplatin resistance of epithelial ovarian cancer cells

DOI: 10.18632/oncotarget.16610

Xiaolan Zhu, Huiling Shen, Xinming Yin, Lulu Long, Xiaofang Chen, Fan Feng, Yueqin Liu, Peiqing Zhao, Yue Xu, Mei Li, Wenlin Xu,  and Yuefeng Li
39154-39166
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Modeling therapeutic response to radioiodine in metastatic thyroid cancer: a proof-of-concept study for individualized medicine

Modeling therapeutic response to radioiodine in metastatic thyroid cancer: a proof-of-concept study for individualized medicine

DOI: 10.18632/oncotarget.16637

Dominique Barbolosi, Ilyssa Summer, Christophe Meille, Raphaël Serre, Antony Kelly, Slimane Zerdoud, Claire Bournaud, Claire Schvartz, Michel Toubeau, Marie-Elisabeth Toubert, Isabelle Keller,  and David Taïeb
39167-39176
Abstract  |   PDF  |  HTML  |  Order a Reprint

The long noncoding RNA ANRIL acts as an oncogene and contributes to paclitaxel resistance of lung adenocarcinoma A549 cells

The long noncoding RNA ANRIL acts as an oncogene and contributes to paclitaxel resistance of lung adenocarcinoma A549 cells

DOI: 10.18632/oncotarget.16640

Ran Xu, Yuqiang Mao, Kuanbing Chen, Wei He, Wenjun Shi,  and Yun Han
39177-39184
Abstract  |   PDF  |  HTML  |  Order a Reprint

PDK1 inhibitor GSK2334470 exerts antitumor activity in multiple myeloma and forms a novel multitargeted combination with dual mTORC1/C2 inhibitor PP242

PDK1 inhibitor GSK2334470 exerts antitumor activity in multiple myeloma and forms a novel multitargeted combination with dual mTORC1/C2 inhibitor PP242

DOI: 10.18632/oncotarget.16642

Chunmei Yang, Xianbo Huang, Hui Liu, Feng Xiao, Jueying Wei, Liangshun You,  and Wenbin Qian
39185-39197
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Programmed death-1 polymorphisms is associated with risk of esophagogastric junction adenocarcinoma in the Chinese Han population: A case-control study involving 2,740 subjects

Programmed death-1 polymorphisms is associated with risk of esophagogastric junction adenocarcinoma in the Chinese Han population: A case-control study involving 2,740 subjects

DOI: 10.18632/oncotarget.17338

Weifeng Tang, Shuchen Chen, Yu Chen, Jihong Lin, Jiangbo Lin, Yafeng Wang, Chao Liu,  and Mingqiang Kang
39198-39208
Abstract  |   PDF  |  HTML  |  Order a Reprint

Upregulation of minichromosome maintenance complex component 3 during epithelial-to-mesenchymal transition in human prostate cancer

Upregulation of minichromosome maintenance complex component 3 during epithelial-to-mesenchymal transition in human prostate cancer

DOI: 10.18632/oncotarget.16835

Paul A. Stewart, Zahraa I. Khamis, Haiyen E. Zhau, Peng Duan, Quanlin Li, Leland W.K. Chung,  and Qing-Xiang Amy Sang
39209-39217
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The Bruton’s tyrosine kinase inhibitor ibrutinib exerts immunomodulatory effects through regulation of tumor-infiltrating macrophages

The Bruton’s tyrosine kinase inhibitor ibrutinib exerts immunomodulatory effects through regulation of tumor-infiltrating macrophages

DOI: 10.18632/oncotarget.16836

Lingyan Ping, Ning Ding, Yunfei Shi, Lixia Feng, Jiao Li, Yalu Liu, Yufu Lin, Cunzhen Shi, Xing Wang, Zhengying Pan, Yuqin Song,  and Jun Zhu
39218-39229
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting CCR2 with its antagonist suppresses viability, motility and invasion by downregulating MMP-9 expression in non-small cell lung cancer cells

Targeting CCR2 with its antagonist suppresses viability, motility and invasion by downregulating MMP-9 expression in non-small cell lung cancer cells

DOI: 10.18632/oncotarget.16837

Jun An, Ying Xue, Meijun Long, Ge Zhang, Junhang Zhang,  and Hang Su
39230-39240
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The expression of histone deacetylase HDAC1 correlates with the progression and prognosis of gastrointestinal malignancy

The expression of histone deacetylase HDAC1 correlates with the progression and prognosis of gastrointestinal malignancy

DOI: 10.18632/oncotarget.16843

Lin-Lin Cao, Zhihong Yue, Lianhua Liu, Lin Pei, Yue Yin, Li Qin, Jie Zhao, Huixin Liu, Hui Wang,  and Mei Jia
39241-39253
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical genomic profiling to identify actionable alterations for investigational therapies in patients with diverse sarcomas

Clinical genomic profiling to identify actionable alterations for investigational therapies in patients with diverse sarcomas

DOI: 10.18632/oncotarget.16845

Roman Groisberg, David S. Hong, Vijaykumar Holla, Filip Janku, Sarina Piha-Paul, Vinod Ravi, Robert Benjamin, Shreyas Kumar Patel, Neeta Somaiah, Anthony Conley, Siraj M. Ali, Alexa B. Schrock, Jeffrey S. Ross, Philip J. Stephens, Vincent A. Miller, Shiraj Sen, Cynthia Herzog, Funda Meric-Bernstam,  and Vivek Subbiah
39254-39267
Abstract  |    |  PDF  |  HTML  |  Order a Reprint

FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma

FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma

DOI: 10.18632/oncotarget.16848

Krittiya Korphaisarn, Van Karlyle Morris, Michael J. Overman, David R. Fogelman, Bryan K. Kee, Kanwal Pratap Singh Raghav, Shanequa Manuel, Imad Shureiqi, Robert A. Wolff, Cathy Eng, David Menter, Stanley R. Hamilton, Scott Kopetz,  and Arvind Dasari
39268-39279
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The SNAIL/miR-128 axis regulated growth, invasion, metastasis, and epithelial-to-mesenchymal transition of gastric cancer

The SNAIL/miR-128 axis regulated growth, invasion, metastasis, and epithelial-to-mesenchymal transition of gastric cancer

DOI: 10.18632/oncotarget.16849

Wei-Wei Yu, Hong Jiang, Cun-Tai Zhang,  and Yang Peng
39280-39295
Abstract  |   PDF  |  HTML  |  Order a Reprint

Identification of rs7350481 at chromosome 11q23.3 as a novel susceptibility locus for metabolic syndrome in Japanese individuals by an exome-wide association study

Identification of rs7350481 at chromosome 11q23.3 as a novel susceptibility locus for metabolic syndrome in Japanese individuals by an exome-wide association study

DOI: 10.18632/oncotarget.16945

Yoshiji Yamada, Jun Sakuma, Ichiro Takeuchi, Yoshiki Yasukochi, Kimihiko Kato, Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Masaaki Muramatsu, Motoji Sawabe, Yoshinori Fujiwara, Yu Taniguchi, Shuichi Obuchi, Hisashi Kawai, Shoji Shinkai, Seijiro Mori, Tomio Arai,  and Masashi Tanaka
39296-39308
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PKC and CaMK-II inhibitions coordinately rescue ischemia-induced GABAergic neuron dysfunction

PKC and CaMK-II inhibitions coordinately rescue ischemia-induced GABAergic neuron dysfunction

DOI: 10.18632/oncotarget.16947

Li Huang, Chun Wang, Shidi Zhao, Rongjing Ge, Sudong Guan,  and Jin-Hui Wang
39309-39322
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Trefoil factor 3 mediation of oncogenicity and chemoresistance in hepatocellular carcinoma is AKT-BCL-2 dependent

Trefoil factor 3 mediation of oncogenicity and chemoresistance in hepatocellular carcinoma is AKT-BCL-2 dependent

DOI: 10.18632/oncotarget.16950

Ming-Liang You, Yi-Jun Chen, Qing-Yun Chong, Ming-Ming Wu, Vijay Pandey, Ru-Mei Chen, Liang Liu, Lan Ma, Zheng-Sheng Wu, Tao Zhu,  and Peter E. Lobie
39323-39344
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elimination of LMP1-expressing cells from a monolayer of gastric cancer AGS cells

Elimination of LMP1-expressing cells from a monolayer of gastric cancer AGS cells

DOI: 10.18632/oncotarget.16996

Yoshitaka Sato, Shingo Ochiai, Takayuki Murata, Teru Kanda, Fumi Goshima,  and Hiroshi Kimura
39345-39355
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Simultaneous exposure to FcγR and FcαR on monocytes and macrophages enhances antitumor activity in vivo

Simultaneous exposure to FcγR and FcαR on monocytes and macrophages enhances antitumor activity in vivo

DOI: 10.18632/oncotarget.17000

Bingyu Li, Lijun Xu, Fei Tao, Kun Xie, Zhiqiang Wu, You Li, Jie Li, Kaiming Chen, Chenyu Pi, Andrew Mendelsohn, James W. Larrick, Hua Gu,  and Jianmin Fang
39356-39366
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognosis of stage III colorectal carcinomas with FOLFOX adjuvant chemotherapy can be predicted by molecular subtype

Prognosis of stage III colorectal carcinomas with FOLFOX adjuvant chemotherapy can be predicted by molecular subtype

DOI: 10.18632/oncotarget.17023

Yujin Kwon, Minhee Park, Mi Jang, Seongju Yun, Won Kyu Kim, Sora Kim, Soonmyung Paik, Hyun Jung Lee, Sungpil Hong, Tae Il Kim, Byungsoh Min,  and Hoguen Kim
39367-39381
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CSFV induced mitochondrial fission and mitophagy to inhibit apoptosis

CSFV induced mitochondrial fission and mitophagy to inhibit apoptosis

DOI: 10.18632/oncotarget.17030

Hongchao Gou, Mingqiu Zhao, Hailuan Xu, Jin Yuan, Wencheng He, Mengjiao Zhu, Hongxing Ding, Lin Yi,  and Jinding Chen
39382-39400
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OVOL2 antagonizes TGF-β signaling to regulate epithelial to mesenchymal transition during mammary tumor metastasis

OVOL2 antagonizes TGF-β signaling to regulate epithelial to mesenchymal transition during mammary tumor metastasis

DOI: 10.18632/oncotarget.17031

Rong-Si Wu, Jing-Jing Hong, Jia-Fa Wu, Shen Yan, Di Wu, Na Liu, Qing-Feng Liu, Qiu-Wan Wu, Yuan-Yuan Xie, Yun-Jia Liu, Zhong-Zheng Zheng, Err-Cheng Chan, Zhi-Ming Zhang,  and Bo-An Li
39401-39416
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A-to-I RNA editing of BLCAP lost the inhibition to STAT3 activation in cervical cancer

A-to-I RNA editing of BLCAP lost the inhibition to STAT3 activation in cervical cancer

DOI: 10.18632/oncotarget.17034

Wen Chen, Wenrong He, Hongbing Cai, Bicheng Hu, Caishang Zheng, Xianliang Ke, Li Xie, Zhenhua Zheng, Xinxing Wu,  and Hanzhong Wang
39417-39429
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma

Dishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma

DOI: 10.18632/oncotarget.17049

Yu-Man Tsui, Karen Man-Fong Sze, Edmund Kwok-Kwan Tung, Daniel Wai-Hung Ho, Terence Kin-Wah Lee,  and Irene Oi-Lin Ng
39430-39442
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dickkopf-related protein 2 induces G0/G1 arrest and apoptosis through suppressing Wnt/β-catenin signaling and is frequently methylated in breast cancer

Dickkopf-related protein 2 induces G0/G1 arrest and apoptosis through suppressing Wnt/β-catenin signaling and is frequently methylated in breast cancer

DOI: 10.18632/oncotarget.17055

Junhao Mu, Tianli Hui, Bianfei Shao, Lili Li, Zhenfang Du, Li Lu, Lin Ye, Shuman Li, Qianqian Li, Qian Xiao, Zhu Qiu, Yan Zhang, Jiangxia Fan, Guosheng Ren, Qian Tao,  and Tingxiu Xiang
39443-39459
Abstract  |   PDF  |  HTML  |  Order a Reprint

Inhibition of exportin-1 function results in rapid cell cycle-associated DNA damage in cancer cells

Inhibition of exportin-1 function results in rapid cell cycle-associated DNA damage in cancer cells

DOI: 10.18632/oncotarget.17063

Russell T. Burke, Joshua M. Marcus,  and James D. Orth
39460-39475
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GLUT1-mediated selective tumor targeting with fluorine containing platinum(II) glycoconjugates

GLUT1-mediated selective tumor targeting with fluorine containing platinum(II) glycoconjugates

DOI: 10.18632/oncotarget.17073

Ran Liu, Zheng Fu, Meng Zhao, Xiangqian Gao, Hong Li, Qian Mi, Pengxing Liu, Jinna Yang, Zhi Yao,  and Qingzhi Gao
39476-39496
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Functional dissection of the role of UHRF1 in the regulation of retinoblastoma methylome

Functional dissection of the role of UHRF1 in the regulation of retinoblastoma methylome

DOI: 10.18632/oncotarget.17078

Guangyan Kan, Heng He, Qi Zhao, Xiubo Li, Min Li, Huasheng Yang,  and Jong Kyong Kim
39497-39511
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A topically-sprayable, activatable fluorescent and retaining probe, SPiDER-βGal for detecting cancer: Advantages of anchoring to cellular proteins after activation

A topically-sprayable, activatable fluorescent and retaining probe, SPiDER-βGal for detecting cancer: Advantages of anchoring to cellular proteins after activation

DOI: 10.18632/oncotarget.17080

Yuko Nakamura, Ai Mochida, Tadanobu Nagaya, Shuhei Okuyama, Fusa Ogata, Peter L. Choyke,  and Hisataka Kobayashi
39512-39521
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cancer stemness and metastatic potential of the novel tumor cell line K3: an inner mutated cell of bone marrow-derived mesenchymal stem cells

Cancer stemness and metastatic potential of the novel tumor cell line K3: an inner mutated cell of bone marrow-derived mesenchymal stem cells

DOI: 10.18632/oncotarget.17133

Hui Qian, Xiaoqing Ding, Jiao Zhang, Fei Mao, Zixuan Sun, Haoyuan Jia, Lei Yin, Mei Wang, Xu Zhang, Bin Zhang, Yongmin Yan, Wei Zhu,  and Wenrong Xu
39522-39533
Abstract  |   PDF  |  HTML  |  Order a Reprint

Platelet-derived growth factor receptor α in hepatocellular carcinoma is a prognostic marker independent of underlying liver cirrhosis

Platelet-derived growth factor receptor α in hepatocellular carcinoma is a prognostic marker independent of underlying liver cirrhosis

DOI: 10.18632/oncotarget.17134

Jung-Hwan Yu, Joon Mee Kim, Ja Kyung Kim, Suk Jin Choi, Kwan Sik Lee, Jin-Woo Lee, Hye Young Chang,  and Jung Il Lee
39534-39546
Abstract  |   PDF  |  HTML  |  Order a Reprint

Nanoparticle-mediated dual delivery of resveratrol and DAP5 ameliorates kidney ischemia/reperfusion injury by inhibiting cell apoptosis and inflammation

Nanoparticle-mediated dual delivery of resveratrol and DAP5 ameliorates kidney ischemia/reperfusion injury by inhibiting cell apoptosis and inflammation

DOI: 10.18632/oncotarget.17135

Yong Xu, Bo Zhang, Da Xie, Yu Hu, Hai-Lun Li, Li-Li Zhong, Hong-Wu Wang, Wei Jiang, Zun-Ping Ke,  and Dong-Hui Zheng
39547-39558
Abstract  |   PDF  |  HTML  |  Order a Reprint

Down-regulation of miR-29b in carcinoma associated fibroblasts promotes cell growth and metastasis of breast cancer

Down-regulation of miR-29b in carcinoma associated fibroblasts promotes cell growth and metastasis of breast cancer

DOI: 10.18632/oncotarget.17136

Yonglei Liu, Jingling Zhang, Xiangjun Sun, Quanping Su,  and Cuiping You
39559-39570
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

WISP-3 inhibition of miR-452 promotes VEGF-A expression in chondrosarcoma cells and induces endothelial progenitor cells angiogenesis

WISP-3 inhibition of miR-452 promotes VEGF-A expression in chondrosarcoma cells and induces endothelial progenitor cells angiogenesis

DOI: 10.18632/oncotarget.17142

Chih-Yang Lin, Huey-En Tzeng, Te-Mao Li, Hsien-Te Chen, Yi Lee, Yi-Chen Yang, Shih-Wei Wang, Wei-Hung Yang,  and Chih-Hsin Tang
39571-39581
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic variation and forensic efficiency of autosomal insertion/deletion polymorphisms in Chinese Bai ethnic group: phylogenetic analysis to other populations

Genetic variation and forensic efficiency of autosomal insertion/deletion polymorphisms in Chinese Bai ethnic group: phylogenetic analysis to other populations

DOI: 10.18632/oncotarget.17137

Chun-Hua Yang, Cai-Yong Yin, Chun-Mei Shen, Yu-Xin Guo, Qian Dong, Jiang-Wei Yan, Hong-Dan Wang, Yu-Dang Zhang, Hao-Tian Meng, Rui Jin, Feng Chen,  and Bo-Feng Zhu
39582-39591
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SIRT3-KLF15 signaling ameliorates kidney injury induced by hypertension

SIRT3-KLF15 signaling ameliorates kidney injury induced by hypertension

DOI: 10.18632/oncotarget.17165

Na Li, Jie Zhang, Xuefang Yan, Chen Zhang, Hui Liu, Xiaolan Shan, Jingyuan Li, Yi Yang, Chengmin Huang, Peng Zhang, Yun Zhang,  and Peili Bu
39592-39604
Abstract  |   PDF  |  HTML  |  Order a Reprint

Overexpression of SphK2 contributes to ATRA resistance in colon cancer through rapid degradation of cytoplasmic RXRα by K48/K63-linked polyubiquitination

Overexpression of SphK2 contributes to ATRA resistance in colon cancer through rapid degradation of cytoplasmic RXRα by K48/K63-linked polyubiquitination

DOI: 10.18632/oncotarget.17174

Wen-Na Shi, Shu-Xiang Cui, Zhi-Yu Song, Shu-Qing Wang, Shi-Yue Sun, Xin-Feng Yu, Ye Li, Yu-Hang Zhang, Zu-Hua Gao,  and Xian-Jun Qu
39605-39617
Abstract  |   PDF  |  HTML  |  Order a Reprint

18F-fluorodeoxyglucose uptake predicts PKM2 expression in lung adenocarcinoma

18F-fluorodeoxyglucose uptake predicts PKM2 expression in lung adenocarcinoma

DOI: 10.18632/oncotarget.17377

Ping Huang, Xiang Zhao, Weiyuan Xiao, Yuqi Dong,  and Guangyu Hu
39618-39626
Abstract  |    |  PDF  |  HTML  |  Order a Reprint

Genetic rearrangements result in altered gene expression and novel fusion transcripts in Sézary syndrome

Genetic rearrangements result in altered gene expression and novel fusion transcripts in Sézary syndrome

DOI: 10.18632/oncotarget.17383

Katarzyna Iżykowska, Grzegorz K. Przybylski, Claudia Gand, Floriane C. Braun, Piotr Grabarczyk, Andreas W. Kuss, Karolina Olek-Hrab, Armando N. Bastidas Torres, Maarten H. Vermeer, Willem H. Zoutman, Cornelis P. Tensen,  and Christian A. Schmidt
39627-39639
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pantoprazole blocks the JAK2/STAT3 pathway to alleviate skeletal muscle wasting in cancer cachexia by inhibiting inflammatory response

Pantoprazole blocks the JAK2/STAT3 pathway to alleviate skeletal muscle wasting in cancer cachexia by inhibiting inflammatory response

DOI: 10.18632/oncotarget.17387

Dunwei Guo, Chaoyi Wang, Qiang Wang, Zhongpeng Qiao,  and Hua Tang
39640-39648
Abstract  |   PDF  |  HTML  |  Order a Reprint

Meta-Analysis

Tea consumption and the risk of biliary tract cancer: a systematic review and dose-response meta-analysis of observational studies

Tea consumption and the risk of biliary tract cancer: a systematic review and dose-response meta-analysis of observational studies

DOI: 10.18632/oncotarget.16963

Jianping Xiong, Jianzhen Lin, Anqiang Wang, Yaqin Wang, Ying Zheng, Xinting Sang, Yiyao Xu, Xin Lu,  and Haitao Zhao
39649-39657
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinicopathologic and prognostic significance of regulatory T cells in patients with hepatocellular carcinoma: a meta-analysis

Clinicopathologic and prognostic significance of regulatory T cells in patients with hepatocellular carcinoma: a meta-analysis

DOI: 10.18632/oncotarget.17340

Lejia Sun, Gang Xu, Wenjun Liao, Huayu Yang, Haifeng Xu, Shunda Du, Haitao Zhao, Xin Lu, Xinting Sang,  and Yilei Mao
39658-39672
Abstract  |   PDF  |  HTML  |  Order a Reprint

Efficacy and safety comparison of chemotherapies for advanced gastric cancer: A network meta-analysis

Efficacy and safety comparison of chemotherapies for advanced gastric cancer: A network meta-analysis

DOI: 10.18632/oncotarget.17784

Jinping Sun, Zheng Ren, Xinfang Sun, Hongtao Hou, Ke Li,  and Quanxing Ge
39673-39682
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

IMRT combined with concurrent chemotherapy plus adjuvant chemotherapy versus IMRT combined with concurrent chemotherapy alone in patients with nasopharyngeal carcinoma

IMRT combined with concurrent chemotherapy plus adjuvant chemotherapy versus IMRT combined with concurrent chemotherapy alone in patients with nasopharyngeal carcinoma

DOI: 10.18632/oncotarget.14799

Qiulu Zhong, Xiaodong Zhu, Ling Li, Song Qu, Zhongguo Liang, Fanyan Zeng,  and Xinbin Pan
39683-39694
Abstract  |   PDF  |  HTML  |  Order a Reprint

Novel phenotypes of NF1 patients from unrelated Chinese families with tibial pseudarthrosis and anemia

Novel phenotypes of NF1 patients from unrelated Chinese families with tibial pseudarthrosis and anemia

DOI: 10.18632/oncotarget.13932

Santasree Banerjee, Dongzhu Lei, Shengran Liang, Li Yang, Saijun Liu, Zhu Wei,  and Jian Ping Tang
39695-39702
Abstract  |   PDF  |  HTML  |  Order a Reprint

Risk factors of locoregional relapse in locally advanced breast cancer treated with neoadjuvant chemotherapy following mastectomy and radiotherapy

Risk factors of locoregional relapse in locally advanced breast cancer treated with neoadjuvant chemotherapy following mastectomy and radiotherapy

DOI: 10.18632/oncotarget.14407

Liang Huang, Sheng Chen, Wentao T. Yang,  and Zhiming Shao
39703-39710
Abstract  |   PDF  |  HTML  |  Order a Reprint

Immunohistochemical profiling of receptor tyrosine kinases, MED12, and TGF-βRII of surgically resected small cell lung cancer, and the potential of c-kit as a prognostic marker

Immunohistochemical profiling of receptor tyrosine kinases, MED12, and TGF-βRII of surgically resected small cell lung cancer, and the potential of c-kit as a prognostic marker

DOI: 10.18632/oncotarget.14410

Hiroshi Yokouchi, Hiroshi Nishihara, Toshiyuki Harada, Takashi Ishida, Shigeo Yamazaki, Hajime Kikuchi, Satoshi Oizumi, Hidetaka Uramoto, Fumihiro Tanaka, Masao Harada, Kenji Akie, Fumiko Sugaya, Yuka Fujita, Kei Takamura, Tetsuya Kojima, Mitsunori Higuchi, Osamu Honjo, Yoshinori Minami, Naomi Watanabe, Aya Goto, Hiroyuki Suzuki, Hirotoshi Dosaka-Akita, Hiroshi Isobe, Masaharu Nishimura,  and Mitsuru Munakata
39711-39726
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tomotherapy as an adjuvant treatment for gastroesophageal junction and stomach cancer may reduce bowel and bone marrow toxicity compared to intensity-modulated radiotherapy and volumetric-modulated arc therapy

Tomotherapy as an adjuvant treatment for gastroesophageal junction and stomach cancer may reduce bowel and bone marrow toxicity compared to intensity-modulated radiotherapy and volumetric-modulated arc therapy

DOI: 10.18632/oncotarget.14459

Xin Wang, Yuan Tian, Yuan Tang, Zhi-Hui Hu, Jia-Jia Zhang, Gui-Shan Fu, Pan Ma, Hua Ren, Tao Zhang, Ning Li, Wen-Yang Liu, Hui Fang, Ye-Xiong Li,  and Jing Jin
39727-39735
Abstract  |   PDF  |  HTML  |  Order a Reprint

Diagnosis of cytomegalovirus pneumonia by quantitative polymerase chain reaction using bronchial washing fluid from patients with hematologic malignancies

Diagnosis of cytomegalovirus pneumonia by quantitative polymerase chain reaction using bronchial washing fluid from patients with hematologic malignancies

DOI: 10.18632/oncotarget.14504

Hwa Young Lee, Chin Kook Rhee, Joon Young Choi, Hea Yon Lee, Jong Wook Lee,  and Dong Gun Lee
39736-39745
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Efficacy of transcatheter arterial chemoembolization for liver metastases arising from pancreatic cancer

Efficacy of transcatheter arterial chemoembolization for liver metastases arising from pancreatic cancer

DOI: 10.18632/oncotarget.14642

Jun-Hui Sun, Tan-Yang Zhou, Yue-Lin Zhang, Guan-Hui Zhou, Chun-Hui Nie, Tong-Yin Zhu, Sheng-Qun Chen, Bao-Quan Wang, Song Ye, Yan Shen, Hua Guo, Wei-Lin Wang,  and Shu-Sen Zheng
39746-39755
Abstract  |   PDF  |  HTML  |  Order a Reprint

Outcome and long-term efficacy of four facio-cervical fields conformal radiotherapy for nasopharyngeal carcinoma

Outcome and long-term efficacy of four facio-cervical fields conformal radiotherapy for nasopharyngeal carcinoma

DOI: 10.18632/oncotarget.14403

Wang Fangzheng, Jiang Chuner, Wang Lei, Chen Weijun, Xu Min, Sun Quanquan, Liu Tongxin, Rihito Aizawa, Masoto Sakamoto,  and Fu Zhenfu
39756-39765
Abstract  |   PDF  |  HTML  |  Order a Reprint

Left ventricular longitudinal strain in soccer referees

Left ventricular longitudinal strain in soccer referees

DOI: 10.18632/oncotarget.15242

Luigi Gianturco, Bruno Bodini, Vincenzo Gianturco, Giuseppina Lippo, Agnese Solbiati,  and Maurizio Turiel
39766-39773
Abstract  |   PDF  |  HTML  |  Order a Reprint

Comparison between proton boron fusion therapy (PBFT) and boron neutron capture therapy (BNCT): a Monte Carlo study

Comparison between proton boron fusion therapy (PBFT) and boron neutron capture therapy (BNCT): a Monte Carlo study

DOI: 10.18632/oncotarget.15700

Joo-Young Jung, Do-Kun Yoon, Brendan Barraclough, Heui Chang Lee, Tae Suk Suh,  and Bo Lu
39774-39781
Abstract  |   PDF  |  HTML  |  Order a Reprint

Reviews

Chemoradiotherapy enhanced the efficacy of radiotherapy in nasopharyngeal carcinoma patients: a network meta-analysis

Chemoradiotherapy enhanced the efficacy of radiotherapy in nasopharyngeal carcinoma patients: a network meta-analysis

DOI: 10.18632/oncotarget.16349

Jian He, Ping Wu, Yaoyun Tang, Sulai Liu, Chubo Xie, Shi Luo, Junfeng Zeng, Jing Xu,  and Suping Zhao
39782-39794
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Angiogenesis in NSCLC: is vessel co-option the trunk that sustains the branches?

Angiogenesis in NSCLC: is vessel co-option the trunk that sustains the branches?

DOI: 10.18632/oncotarget.7794

Ana Luísa Coelho, Mónica Patrícia Gomes, Raquel Jorge Catarino, Christian Rolfo, Agostinho Marques Lopes, Rui Manuel Medeiros,  and António Manuel Araújo
39795-39804
Abstract  |   PDF  |  HTML  |  Order a Reprint

Carfilzomib/pomalidomide single-agent or in combination with other agents for the management of relapsed/refractory multiple myeloma: a meta-analysis of 37 trials

Carfilzomib/pomalidomide single-agent or in combination with other agents for the management of relapsed/refractory multiple myeloma: a meta-analysis of 37 trials

DOI: 10.18632/oncotarget.10768

Yandun Zou, Xiaoyan Ma, Haiying Yu, Chunling Hu, Limei Fan,  and Xuehong Ran
39805-39817
Abstract  |   PDF  |  HTML  |  Order a Reprint

Association between the BRCA2 rs144848 polymorphism and cancer susceptibility: a meta-analysis

Association between the BRCA2 rs144848 polymorphism and cancer susceptibility: a meta-analysis

DOI: 10.18632/oncotarget.16242

Qiuyan Li, Rongwei Guan, Yuandong Qiao, Chang Liu, Ning He, Xuelong Zhang, Xueyuan Jia, Haiming Sun, Jingcui Yu,  and Lidan Xu
39818-39832
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A review and outlook in the treatment of osteosarcoma and other deep tumors with photodynamic therapy: from basic to deep

A review and outlook in the treatment of osteosarcoma and other deep tumors with photodynamic therapy: from basic to deep

DOI: 10.18632/oncotarget.16243

Wei Yu, Jian Zhu, Yitian Wang, Junjie Wang, Weijing Fang, Kaishun Xia, Jianlin Shao, Minzu Wu, Bing Liu, Chengzhen Liang, Chengyi Ye,  and Huimin Tao
39833-39848
Abstract  |   PDF  |  HTML  |  Order a Reprint

The serum 25-hydroxyvitamin D levels and hip fracture risk: a meta-analysis of prospective cohort studies

The serum 25-hydroxyvitamin D levels and hip fracture risk: a meta-analysis of prospective cohort studies

DOI: 10.18632/oncotarget.16337

Qing-Bo Lv, Xiang Gao, Xiang Liu, Zhen-Xuan Shao, Qian-Hui Xu, Li Tang, Yong-Long Chi,  and Ai-Min Wu
39849-39858
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Roles of long noncoding RNAs in colorectal cancer metastasis

Roles of long noncoding RNAs in colorectal cancer metastasis

DOI: 10.18632/oncotarget.16339

He Li, Si-Qing Ma, Jin Huang, Xiao-Ping Chen,  and Hong-Hao Zhou
39859-39876
Abstract  |   PDF  |  HTML  |  Order a Reprint

An exploration of the role of a fish-oriented diet in cognitive decline: a systematic review of the literature

An exploration of the role of a fish-oriented diet in cognitive decline: a systematic review of the literature

DOI: 10.18632/oncotarget.16347

Ling-Feng Zeng, Ye Cao, Wei-Xiong Liang, Wen-Hu Bao, Jian-Ke Pan, Qi Wang, Jun Liu, Hao-Dong Liang, Hui Xie, Yan-Ting Chai, Zi-Tong Guan, Qian Cao, Xiao-Yan Li, Lei Yang, Wei-Hua Xu, Sui-Qing Mi,  and Ning-Sheng Wang
39877-39895
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Melatonin for the prevention and treatment of cancer

Melatonin for the prevention and treatment of cancer

DOI: 10.18632/oncotarget.16379

Ya Li, Sha Li, Yue Zhou, Xiao Meng, Jiao-Jiao Zhang, Dong-Ping Xu,  and Hua-Bin Li
39896-39921
Abstract  |   PDF  |  HTML  |  Order a Reprint

HIV-1 Tat inhibits EAAT-2 through AEG-1 upregulation in models of HIV-associated neurocognitive disorder

HIV-1 Tat inhibits EAAT-2 through AEG-1 upregulation in models of HIV-associated neurocognitive disorder

DOI: 10.18632/oncotarget.16485

Xiang Ye, Yu Zhang, Qiping Xu, Honghua Zheng, Xiaoyan Wu, Jinhua Qiu, Zhou Zhang, Wei Wang, Yiming Shao,  and Hui Qin Xing
39922-39934
Abstract  |   PDF  |  HTML  |  Order a Reprint

Corrections

Correction: p63α modulates c-Myc activity via direct interaction and regulation of MM1 protein stability

Correction: p63α modulates c-Myc activity via direct interaction and regulation of MM1 protein stability

DOI: 10.18632/oncotarget.18439

Anning Han, Juan Li, Yimin Li, Yang Wang, Johann Bergholz, Yujun Zhang, Chenghua Li,  and Zhi-Xiong Xiao
39935-39935
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Correction: Th1high in tumor microenvironment is an indicator of poor prognosis for patients with NSCLC

Correction: Th1high in tumor microenvironment is an indicator of poor prognosis for patients with NSCLC

DOI: 10.18632/oncotarget.18440

Huang Jian, Shen Fangrong, Huang Haitao, Ling Chunhua,  and Zhang Guangbo
39936-39936
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