Oncotarget

Vol 8, No 21

May 23, 2017

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About The Cover

The cover for issue 21 of Oncotarget features Figure 6B, "p53 knockdown improves progerin-induced inhibition of VSMC growth," from Kinoshita, et al.

Table of Contents

News

Combination strategies enhance oncolytic virotherapy

Combination strategies enhance oncolytic virotherapy

https://doi.org/10.18632/oncotarget.17643

Gregory K. Friedman, James M. Markert,  and George Yancey Gillespie
34020-34021
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Editorial

Multivariate approaches to behavioral physiology

Multivariate approaches to behavioral physiology

https://doi.org/10.18632/oncotarget.16612

Maurizio Casarrubea, Andrea Santangelo,  and Giuseppe Crescimanno
34022-34023
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A neurorestorative approach to Parkinson’s disease

A neurorestorative approach to Parkinson’s disease

https://doi.org/10.18632/oncotarget.17108

Giovanni Diana, Maria Teresa Ciotti,  and Marco Musilli
34024-34025
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M channels and stress response

M channels and stress response

https://doi.org/10.18632/oncotarget.17110

Sheng Wang, Fang Yuan,  and De-Pei Li
34026-34027
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ATXN2 a culprit with multiple facets

ATXN2 a culprit with multiple facets

https://doi.org/10.18632/oncotarget.17112

Aurore Nkiliza,  and Marie-Christine Chartier-Harlin
34028-34029
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HDAC/IKK inhibition therapies in solid tumors

HDAC/IKK inhibition therapies in solid tumors

https://doi.org/10.18632/oncotarget.17512

Ivana Vancurova, Himavanth R. Gatla,  and Ales Vancura
34030-34031
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Priority Research Papers

Rad52 deficiency decreases development of lung squamous cell carcinomas by enhancing immuno-surveillance

Rad52 deficiency decreases development of lung squamous cell carcinomas by enhancing immuno-surveillance

https://doi.org/10.18632/oncotarget.16371

Rachel Lieberman, Jing Pan, Qi Zhang,  and Ming You
34032-34044
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Research Papers: Gerotarget (Focus on Aging)

Progerin impairs vascular smooth muscle cell growth via the DNA damage response pathway

Progerin impairs vascular smooth muscle cell growth via the DNA damage response pathway

https://doi.org/10.18632/oncotarget.15973

Daisuke Kinoshita, Ayako Nagasawa, Ippei Shimizu, Takashi K. Ito, Yohko Yoshida, Masanori Tsuchida, Atsushi Iwama, Toshiya Hayano,  and Tohru Minamino
34045-34056
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Examining the association between anthropometric parameters and telomere length and mortality risk

Examining the association between anthropometric parameters and telomere length and mortality risk

https://doi.org/10.18632/oncotarget.15976

Chen-Jung Wu, Tung-Wei Kao, Yuan-Yung Lin, Fang-Yih Liaw, Li-Wei Wu, Yaw-Wen Chang, Tao-Chun Peng,  and Wei-Liang Chen
34057-34069
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Research Papers: Pathology

Comparative analysis of HPV16 gene expression profiles in cervical and in oropharyngeal squamous cell carcinoma

Comparative analysis of HPV16 gene expression profiles in cervical and in oropharyngeal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.15977

Andrea Cerasuolo, Clorinda Annunziata, Marianna Tortora, Noemy Starita, Giovanni Stellato, Stefano Greggi, Maria Grazia Maglione, Franco Ionna, Simona Losito, Gerardo Botti, Luigi Buonaguro, Franco M. Buonaguro,  and Maria Lina Tornesello
34070-34081
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Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice

Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice

https://doi.org/10.18632/oncotarget.16133

Vinodkumar B. Pillai, Abhinav Kanwal, Yong Hu Fang, Willard W. Sharp, Sadhana Samant, Jack Arbiser,  and Mahesh P. Gupta
34082-34098
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Research Papers: Immunology

Inhibitor of Tec kinase, LFM-A13, decreases pro-inflammatory mediators production in LPS-stimulated RAW264.7 macrophages via NF-κB pathway

Inhibitor of Tec kinase, LFM-A13, decreases pro-inflammatory mediators production in LPS-stimulated RAW264.7 macrophages via NF-κB pathway

https://doi.org/10.18632/oncotarget.16212

Fei Wang, Wei Zhang, Chao Wang, Xu Fang, Hao Cheng, Sheng Liu,  and Xu-Lin Chen
34099-34110
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Research Papers: Autophagy and Cell Death

Lithium protects hippocampal progenitors, cognitive performance and hypothalamus–pituitary function after irradiation to the juvenile rat brain

Lithium protects hippocampal progenitors, cognitive performance and hypothalamus–pituitary function after irradiation to the juvenile rat brain

https://doi.org/10.18632/oncotarget.16292

Kai Zhou, Cuicui Xie, Malin Wickström, Amalia M. Dolga, Yaodong Zhang, Tao Li, Yiran Xu, Carsten Culmsee, Per Kogner, Changlian Zhu,  and Klas Blomgren
34111-34127
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Research Papers

Remote reprogramming of hepatic circadian transcriptome by breast cancer

Remote reprogramming of hepatic circadian transcriptome by breast cancer

https://doi.org/10.18632/oncotarget.16699

Hiroaki Hojo, Sora Enya, Miki Arai, Yutaka Suzuki, Takashi Nojiri, Kenji Kangawa, Shinsuke Koyama,  and Shinpei Kawaoka
34128-34140
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Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model

Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model

https://doi.org/10.18632/oncotarget.9388

Tsion Zewdu Minas, Didier Surdez, Tahereh Javaheri, Miwa Tanaka, Michelle Howarth, Hong-Jun Kang, Jenny Han, Zhi-Yan Han, Barbara Sax, Barbara E. Kream, Sung-Hyeok Hong, Haydar Çelik, Franck Tirode, Jan Tuckermann, Jeffrey A. Toretsky, Lukas Kenner, Heinrich Kovar, Sean Lee, E. Alejandro Sweet-Cordero, Takuro Nakamura, Richard Moriggl, Olivier Delattre,  and Aykut Üren
34141-34163
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Upregulation of the long non-coding RNA PVT1 promotes esophageal squamous cell carcinoma progression by acting as a molecular sponge of miR-203 and LASP1

Upregulation of the long non-coding RNA PVT1 promotes esophageal squamous cell carcinoma progression by acting as a molecular sponge of miR-203 and LASP1

https://doi.org/10.18632/oncotarget.15878

Pin-Dong Li, Jian-Li Hu, Charlie Ma, Hong Ma, Jing Yao, Li-Li Chen, Jing Chen, Tian-Tian Cheng, Kun-Yu Yang, Gang Wu, Wen-Jie Zhang,  and Ru-Bo Cao
34164-34176
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CRISPR Cas9-guided chromatin immunoprecipitation identifies miR483 as an epigenetic modulator of IGF2 imprinting in tumors

CRISPR Cas9-guided chromatin immunoprecipitation identifies miR483 as an epigenetic modulator of IGF2 imprinting in tumors

https://doi.org/10.18632/oncotarget.10918

Yiqun Zhang, Ji-Fan Hu, Hong Wang, Jiuwei Cui, Sujun Gao, Andrew R. Hoffman,  and Wei Li
34177-34190
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Involvement of heparanase in the pathogenesis of acute kidney injury: nephroprotective effect of PG545

Involvement of heparanase in the pathogenesis of acute kidney injury: nephroprotective effect of PG545

https://doi.org/10.18632/oncotarget.16573

Zaid Abassi, Shadi Hamoud, Ahmad Hassan, Iyad Khamaysi, Omri Nativ, Samuel N. Heyman, Rabia Shekh Muhammad, Neta Ilan, Preeti Singh, Edward Hammond, Gianluigi Zaza, Antonio Lupo, Maurizio Onisto, Gloria Bellin, Valentina Masola, Israel Vlodavsky,  and Giovani Gambaro
34191-34204
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Employing an orthotopic model to study the role of epithelial-mesenchymal transition in bladder cancer metastasis

Employing an orthotopic model to study the role of epithelial-mesenchymal transition in bladder cancer metastasis

https://doi.org/10.18632/oncotarget.11009

Beat Roth, Isuru Jayaratna, Debasish Sundi, Tiewei Cheng, Jonathan Melquist, Woonyoung Choi, Sima Porten, Giovanni Nitti, Neema Navai, Matthew Wszolek, Charles Guo, Bogdan Czerniak, David McConkey,  and Colin Dinney
34205-34222
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Isoliquiritigenin suppresses human T Lymphocyte activation via covalently binding cysteine 46 of IκB kinase

Isoliquiritigenin suppresses human T Lymphocyte activation via covalently binding cysteine 46 of IκB kinase

https://doi.org/10.18632/oncotarget.11934

Fenggen Yan, Fen Yang, Rui Wang, Xiao Jun Yao, Liping Bai, Xing Zeng, JiaJun Huang, Vincent Kam Wai Wong, Christopher Wai Kei Lam, Hua Zhou, Xiaohui Su, Juan Liu, Ting Li,  and Liang Liu
34223-34235
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of skin-related lncRNAs as potential biomarkers that are involved in Wnt pathways in keloids

Identification of skin-related lncRNAs as potential biomarkers that are involved in Wnt pathways in keloids

https://doi.org/10.18632/oncotarget.15880

Xiao-Jie Sun, Qiang Wang, Baofeng Guo, Xian-Ying Liu,  and Bing Wang
34236-34244
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Embryonic signature distinguishes pediatric and adult rhabdoid tumors from other SMARCB1-deficient cancers

Embryonic signature distinguishes pediatric and adult rhabdoid tumors from other SMARCB1-deficient cancers

https://doi.org/10.18632/oncotarget.15939

Wilfrid Richer, Julien Masliah-Planchon, Nathalie Clement, Irene Jimenez, Laetitia Maillot, David Gentien, Benoît Albaud, Walid Chemlali, Christine Galant, Frederique Larousserie, Pascaline Boudou-Rouquette, Amaury Leruste, Celine Chauvin, Zhi Yan Han, Jean-Michel Coindre, Pascale Varlet, Paul Freneaux, Dominique Ranchère-Vince, Olivier Delattre,  and Franck Bourdeaut
34245-34257
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Foxo3a-dependent Bim transcription protects mice from a high fat diet via inhibition of activation of the NLRP3 inflammasome by facilitating autophagy flux in Kupffer cells

Foxo3a-dependent Bim transcription protects mice from a high fat diet via inhibition of activation of the NLRP3 inflammasome by facilitating autophagy flux in Kupffer cells

https://doi.org/10.18632/oncotarget.15946

Yan Liu, Wenfeng Zhang, Xiaoling Wu,  and Jianping Gong
34258-34267
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification and characterization of RASSF1C piRNA target genes in lung cancer cells

Identification and characterization of RASSF1C piRNA target genes in lung cancer cells

https://doi.org/10.18632/oncotarget.15965

Mark E. Reeves, Mathew Firek, Abdullaati Jliedi,  and Yousef G. Amaar
34268-34282
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Detection of COPB2 as a KRAS synthetic lethal partner through integration of functional genomics screens

Detection of COPB2 as a KRAS synthetic lethal partner through integration of functional genomics screens

https://doi.org/10.18632/oncotarget.16079

Eleni G. Christodoulou, Hai Yang, Franziska Lademann, Christian Pilarsky, Andreas Beyer,  and Michael Schroeder
34283-34297
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epha3 acts as proangiogenic factor in multiple myeloma

Epha3 acts as proangiogenic factor in multiple myeloma

https://doi.org/10.18632/oncotarget.16100

Antonella Caivano, Francesco La Rocca, Ilaria Laurenzana, Tiziana Annese, Roberto Tamma, Ubaldo Famigliari, Vittorio Simeon, Stefania Trino, Luciana De Luca, Oreste Villani, Simona Berardi, Antonio Basile, Angelo Vacca, Giuseppe Saglio, Luigi Del Vecchio, Pellegrino Musto,  and Daniela Cilloni
34298-34309
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Robust in-silico identification of cancer cell lines based on next generation sequencing

Robust in-silico identification of cancer cell lines based on next generation sequencing

https://doi.org/10.18632/oncotarget.16110

Raik Otto, Christine Sers,  and Ulf Leser
34310-34320
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association between hOGG1 polymorphism rs1052133 and gastric cancer

Association between hOGG1 polymorphism rs1052133 and gastric cancer

https://doi.org/10.18632/oncotarget.16124

Dingding Zhang, Xiaoxin Guo, Jinliang Hu, Guangqun Zeng, Maomin Huang, Dandan Qi,  and Bo Gong
34321-34329
Abstract  |  PDF  |  HTML  |  Order a Reprint

iTRAQ-based quantitative proteomic analysis of Yamanaka factors reprogrammed breast cancer cells

iTRAQ-based quantitative proteomic analysis of Yamanaka factors reprogrammed breast cancer cells

https://doi.org/10.18632/oncotarget.16125

Kun Wang, Zhiyan Shan, Lian Duan, Tiantian Gong, Feng Liu, Yue Zhang, Zhendong Wang, Jingling Shen,  and Lei Lei
34330-34339
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Meta-analysis of oxaliplatin-based versus fluorouracil-based neoadjuvant chemoradiotherapy and adjuvant chemotherapy for locally advanced rectal cancer

Meta-analysis of oxaliplatin-based versus fluorouracil-based neoadjuvant chemoradiotherapy and adjuvant chemotherapy for locally advanced rectal cancer

https://doi.org/10.18632/oncotarget.16127

Xing-Li Fu, Zheng Fang, Liang-Hui Shu, Guo-Qing Tao, Jian-Qiang Wang, Zhi-Lian Rui, Yong-Jie Zhang,  and Zhi-Qiang Tian
34340-34351
Abstract  |  PDF  |  HTML  |  Order a Reprint

Downregulation of phosphorylated MKK4 is associated with a poor prognosis in colorectal cancer patients

Downregulation of phosphorylated MKK4 is associated with a poor prognosis in colorectal cancer patients

https://doi.org/10.18632/oncotarget.16128

Pu-Ning Wang, Jun Huang, Ying-Hua Duan, Jia-Min Zhou, Pin-Zhu Huang, Xin-Juan Fan, Yan Huang, Lei Wang, Huan-Liang Liu, Jian-Ping Wang,  and Mei-Jin Huang
34352-34361
Abstract  |  PDF  |  HTML  |  Order a Reprint

Notch3 overexpression enhances progression and chemoresistance of urothelial carcinoma

Notch3 overexpression enhances progression and chemoresistance of urothelial carcinoma

https://doi.org/10.18632/oncotarget.16156

Heng Zhang, Limei Liu, Chungang Liu, Jinhong Pan, Gensheng Lu, Zhansong Zhou, Zhiwen Chen,  and Cheng Qian
34362-34373
Abstract  |  PDF  |  HTML  |  Order a Reprint

The long non-coding RNA NONHSAG026900 predicts prognosis as a favorable biomarker in patients with diffuse large B-cell lymphoma

The long non-coding RNA NONHSAG026900 predicts prognosis as a favorable biomarker in patients with diffuse large B-cell lymphoma

https://doi.org/10.18632/oncotarget.16163

Shuangtao Zhao, Shuangsang Fang, Yanhua Liu, Xixi Li, Shengyou Liao, Jinwen Chen, Jingjia Liu, Lianhe Zhao, Hui Li, Wei Zhou, Wenzhi Shen, Xiaoli Dong, Rong Xiang, Luhua Wang,  and Yi Zhao
34374-34386
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High TGF-β1 expression predicts poor disease prognosis in hepatocellular carcinoma patients

High TGF-β1 expression predicts poor disease prognosis in hepatocellular carcinoma patients

https://doi.org/10.18632/oncotarget.16166

Li Peng, Xiao-Qing Yuan, Chao-Yang Zhang, Fei Ye, Hui-Fang Zhou, Wen-Ling Li, Zhao-Yang Liu, Ya-Qin Zhang, Xi Pan,  and Guan-Cheng Li
34387-34397
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gene- gene interaction between PPARG and CYP1A1 gene on coronary artery disease in the Chinese Han population

Gene- gene interaction between PPARG and CYP1A1 gene on coronary artery disease in the Chinese Han population

https://doi.org/10.18632/oncotarget.16186

Xiaojiang Zhang, Shuzheng Lv, Chengjun Guo, Conghong Shi, Yunpeng Chi, Lin Zhao, Guozhong Wang,  and Zhisheng Wang
34398-34404
Abstract  |  PDF  |  HTML  |  Order a Reprint

Curcumin blocks autophagy and activates apoptosis of malignant mesothelioma cell lines and increases the survival of mice intraperitoneally transplanted with a malignant mesothelioma cell line

Curcumin blocks autophagy and activates apoptosis of malignant mesothelioma cell lines and increases the survival of mice intraperitoneally transplanted with a malignant mesothelioma cell line

https://doi.org/10.18632/oncotarget.14907

Laura Masuelli, Monica Benvenuto, Enrica Di Stefano, Rosanna Mattera, Massimo Fantini, Giuseppina De Feudis, Enrico De Smaele, Ilaria Tresoldi, Maria Gabriella Giganti, Andrea Modesti,  and Roberto Bei
34405-34422
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Relationship of p73 gene polymorphism and additional gene-smoking and gene-obesity interaction with non-small cell lung cancer risk

Relationship of p73 gene polymorphism and additional gene-smoking and gene-obesity interaction with non-small cell lung cancer risk

https://doi.org/10.18632/oncotarget.16257

Qiuge Wu, Yan Shi, Lulu Ge, Dongbo Ma, Hui Zhang,  and Jing Wang
34423-34428
Abstract  |  PDF  |  HTML  |  Order a Reprint

Long noncoding RNA PCAT-14 induces proliferation and invasion by hepatocellular carcinoma cells by inducing methylation of miR-372

Long noncoding RNA PCAT-14 induces proliferation and invasion by hepatocellular carcinoma cells by inducing methylation of miR-372

https://doi.org/10.18632/oncotarget.16260

Yawei Wang, Ye Hu, Gang Wu, Ye Yang, Yanqing Tang, Wanchuan Zhang, Kaiyu Wang, Yu Liu, Xin Wang,  and Tiemin Li
34429-34441
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of long non-coding RNAs that stimulate cell survival in bladder cancer

Identification of long non-coding RNAs that stimulate cell survival in bladder cancer

https://doi.org/10.18632/oncotarget.16284

Aleksandra M. Dudek, Sabrina J. Boer, Nanda Boon, J. Alfred Witjes, Lambertus A.L.M. Kiemeney,  and Gerald W. Verhaegh
34442-34452
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Thymoquinone exerts potent growth-suppressive activity on leukemia through DNA hypermethylation reversal in leukemia cells

Thymoquinone exerts potent growth-suppressive activity on leukemia through DNA hypermethylation reversal in leukemia cells

https://doi.org/10.18632/oncotarget.16431

Jiuxia Pang, Na Shen, Fei Yan, Na Zhao, Liping Dou, Lai-Chu Wu, Christopher L. Seiler, Li Yu, Ke Yang, Veronika Bachanova, Eric Weaver, Natalia Y. Tretyakova,  and Shujun Liu
34453-34467
Abstract  |  PDF  |  HTML  |  Order a Reprint

A six-microRNA signature in plasma was identified as a potential biomarker in diagnosis of esophageal squamous cell carcinoma

A six-microRNA signature in plasma was identified as a potential biomarker in diagnosis of esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.16519

Xin Zhou, Wei Wen, Jun Zhu, Zebo Huang, Lan Zhang, Huo Zhang, Lian-Wen Qi, Xia Shan, Tongshan Wang, Wenfang Cheng, Danxia Zhu, Yin Yin, Yan Chen, Wei Zhu, Yongqian Shu,  and Ping Liu
34468-34480
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

BALB/c mice immunized with a combination of virus-like particles incorporating Kaposi sarcoma-associated herpesvirus (KSHV) envelope glycoproteins gpK8.1, gB, and gH/gL induced comparable serum neutralizing antibody activity to UV-inactivated KSHV

BALB/c mice immunized with a combination of virus-like particles incorporating Kaposi sarcoma-associated herpesvirus (KSHV) envelope glycoproteins gpK8.1, gB, and gH/gL induced comparable serum neutralizing antibody activity to UV-inactivated KSHV

https://doi.org/10.18632/oncotarget.15605

Anne K. Barasa, Peng Ye, Meredith Phelps, Ganapathiram T. Arivudainambi, Timelia Tison,  and Javier Gordon Ogembo
34481-34497
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

18F-deoxyglucose positron emission tomography/computed tomography to predict local failure in esophageal squamous cell carcinoma

18F-deoxyglucose positron emission tomography/computed tomography to predict local failure in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.15606

Bingjie Fan, Pingping Fan, Li Kong, Xindong Sun, Shuqiang Zhao, Xiaorong Sun, Zheng Fu, Jinsong Zheng, Li Ma, Shijiang Wang, Man Hu,  and Jinming Yu
34498-34506
Abstract  |  PDF  |  HTML  |  Order a Reprint

Human papillomavirus infection as a prognostic marker for lung adenocarcinoma: a systematic review and meta-analysis

Human papillomavirus infection as a prognostic marker for lung adenocarcinoma: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.15671

Lanwei Guo, Shuzheng Liu, Shaokai Zhang, Qiong Chen, Meng Zhang, Peiliang Quan,  and Xibin Sun
34507-34515
Abstract  |  PDF  |  HTML  |  Order a Reprint

NDV-D90 suppresses growth of gastric cancer and cancer-related vascularization

NDV-D90 suppresses growth of gastric cancer and cancer-related vascularization

https://doi.org/10.18632/oncotarget.16563

Hong Sui, Kaibing Wang, Rui Xie, Xi Li, Kunpeng Li, Yuxian Bai, Xishan Wang, Bin Bai, Dan Chen, Jiazhuang Li,  and Baozhong Shen
34516-34524
Abstract  |  PDF  |  HTML  |  Order a Reprint

Citrinin exposure affects oocyte maturation and embryo development by inducing oxidative stress-mediated apoptosis

Citrinin exposure affects oocyte maturation and embryo development by inducing oxidative stress-mediated apoptosis

https://doi.org/10.18632/oncotarget.15776

Yu Wu, Na Zhang, Ying-Hua Li, Liang Zhao, Mo Yang, Yimei Jin, Yong-Nan Xu,  and Hongyan Guo
34525-34533
Abstract  |  PDF  |  HTML  |  Order a Reprint

Transcriptional landscape of human cancers

Transcriptional landscape of human cancers

https://doi.org/10.18632/oncotarget.15837

Mengyuan Li, Qingrong Sun,  and Xiaosheng Wang
34534-34551
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting mantle cell lymphoma metabolism and survival through simultaneous blockade of mTOR and nuclear transporter exportin-1

Targeting mantle cell lymphoma metabolism and survival through simultaneous blockade of mTOR and nuclear transporter exportin-1

https://doi.org/10.18632/oncotarget.16602

Kazumasa Sekihara, Kaori Saitoh, Lina Han, Stefan Ciurea, Shinichi Yamamoto, Mika Kikkawa, Saiko Kazuno, Hikari Taka, Naoko Kaga, Hajime Arai, Takashi Miida, Michael Andreeff, Marina Konopleva,  and Yoko Tabe
34552-34564
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reprogramming induced by isoliquiritigenin diminishes melanoma cachexia through mTORC2-AKT-GSK3β signaling

Reprogramming induced by isoliquiritigenin diminishes melanoma cachexia through mTORC2-AKT-GSK3β signaling

https://doi.org/10.18632/oncotarget.16655

Xiao-Yu Chen, De-Fang Li, Ji-Chun Han, Bo Wang, Zheng-Ping Dong, Li-Na Yu, Zhao-Hai Pan, Chuan-Jun Qu, Ying Chen, Shi-Guo Sun,  and Qiu-Sheng Zheng
34565-34575
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Saline is a more appropriate solution for microvesicles for flow cytometric analyses

Saline is a more appropriate solution for microvesicles for flow cytometric analyses

https://doi.org/10.18632/oncotarget.15987

Xing Xin, Peiling Zhang, Xing Fu, Xia Mao, Fankai Meng, Ming Tian, Xiaojian Zhu, Hanying Sun, Li Meng,  and Jianfeng Zhou
34576-34585
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Discovery and characterization of small molecule Rac1 inhibitors

Discovery and characterization of small molecule Rac1 inhibitors

https://doi.org/10.18632/oncotarget.16656

Jamie L. Arnst, Ashley L. Hein, Margaret A. Taylor, Nick Y. Palermo, Jacob I. Contreras, Yogesh A. Sonawane, Andrew O. Wahl, Michel M. Ouellette, Amarnath Natarajan,  and Ying Yan
34586-34600
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Whole-genome expression analyses of type 2 diabetes in human skin reveal altered immune function and burden of infection

Whole-genome expression analyses of type 2 diabetes in human skin reveal altered immune function and burden of infection

https://doi.org/10.18632/oncotarget.16118

Chun Wu, Xiaopan Chen, Jing Shu,  and Chun-Ting Lee
34601-34609
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dietary score and the risk of oral cancer: a case-control study in southeast China

Dietary score and the risk of oral cancer: a case-control study in southeast China

https://doi.org/10.18632/oncotarget.16659

Fa Chen, Lingjun Yan, Lisong Lin, Fengqiong Liu, Yu Qiu, Jing Wang, Junfeng Wu, Fangping Liu, Jiangfeng Huang, Lin Cai,  and Baochang He
34610-34616
Abstract  |  PDF  |  HTML  |  Order a Reprint

Usefulness of the MRP2 promoter to overcome the chemoresistance of gastrointestinal and liver tumors by enhancing the expression of the drug transporter OATP1B1

Usefulness of the MRP2 promoter to overcome the chemoresistance of gastrointestinal and liver tumors by enhancing the expression of the drug transporter OATP1B1

https://doi.org/10.18632/oncotarget.16119

Elisa Herraez, Laura Sanchez-Vicente, Rocio I.R. Macias, Oscar Briz,  and Jose J.G. Marin
34617-34629
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A functional variant at the miRNA binding site in HMGB1 gene is associated with risk of oral squamous cell carcinoma

A functional variant at the miRNA binding site in HMGB1 gene is associated with risk of oral squamous cell carcinoma

https://doi.org/10.18632/oncotarget.16120

Chiao-Wen Lin, Ying-Erh Chou, Chia-Ming Yeh, Shun-Fa Yang, Chun-Yi Chuang,  and Yu-Fan Liu
34630-34642
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Use of acetaminophen and risk of endometrial cancer: evidence from observational studies

Use of acetaminophen and risk of endometrial cancer: evidence from observational studies

https://doi.org/10.18632/oncotarget.16663

Yuan-Yuan Ding, Peng Yao, Surya Verma, Zhen-Kai Han, Tao Hong, Yong-Qiang Zhu,  and Hong-Xi Li
34643-34651
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DNA methylation of METTL7A gene body regulates its transcriptional level in thyroid cancer

DNA methylation of METTL7A gene body regulates its transcriptional level in thyroid cancer

https://doi.org/10.18632/oncotarget.16147

Shasha Zhou, Yihang Shen, Min Zheng, Linlin Wang, Raymond Che, Wanning Hu,  and Pin Li
34652-34660
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Changes in T-cell subpopulations and cytokine network during early period of ibrutinib therapy in chronic lymphocytic leukemia patients: the significant decrease in T regulatory cells number

Changes in T-cell subpopulations and cytokine network during early period of ibrutinib therapy in chronic lymphocytic leukemia patients: the significant decrease in T regulatory cells number

https://doi.org/10.18632/oncotarget.16148

Monika Podhorecka, Aneta Goracy, Agnieszka Szymczyk, Malgorzata Kowal, Blanca Ibanez, Olga Jankowska-Lecka, Arkadiusz Macheta, Aleksandra Nowaczynska, Elzbieta Drab-Urbanek, Sylwia Chocholska, Dariusz Jawniak,  and Marek Hus
34661-34669
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Subcloning and characterization of highly metastatic cells derived from human esophageal squamous cell carcinoma KYSE150 cells by in vivo selection

Subcloning and characterization of highly metastatic cells derived from human esophageal squamous cell carcinoma KYSE150 cells by in vivo selection

https://doi.org/10.18632/oncotarget.16668

Masafumi Okuda, Jun Inoue, Naoto Fujiwara, Tatsuyuki Kawano,  and Johji Inazawa
34670-34677
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MicroRNA-100 suppresses human osteosarcoma cell proliferation and chemo-resistance via ZNRF2

MicroRNA-100 suppresses human osteosarcoma cell proliferation and chemo-resistance via ZNRF2

https://doi.org/10.18632/oncotarget.16149

Qiang Xiao, Yu Yang, Qing An,  and Yong Qi
34678-34686
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of a novel functional JAK1 S646P mutation in acute lymphoblastic leukemia

Identification of a novel functional JAK1 S646P mutation in acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.16670

Qian Li, Botao Li, Liangding Hu, Hongmei Ning, Min Jiang, Danhong Wang, Tingting Liu, Bin Zhang,  and Hu Chen
34687-34697
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-590-3p suppresses epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma by inhibiting SIP1 expression

MiR-590-3p suppresses epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma by inhibiting SIP1 expression

https://doi.org/10.18632/oncotarget.16150

Chao Zu, Shizhang Liu, Wei Cao, Zongzhi Liu, Hui Qiang, Yong Li, Chong Cheng, Le Ji, Jianhui Li,  and Jingyuan Li
34698-34708
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

In vivo evaluation of the effects of simultaneous inhibition of GLUT-1 and HIF-1α by antisense oligodeoxynucleotides on the radiosensitivity of laryngeal carcinoma using micro 18F-FDG PET/CT

In vivo evaluation of the effects of simultaneous inhibition of GLUT-1 and HIF-1α by antisense oligodeoxynucleotides on the radiosensitivity of laryngeal carcinoma using micro 18F-FDG PET/CT

https://doi.org/10.18632/oncotarget.16671

Li-Fang Shen, Xin Zhao, Shui-Hong Zhou, Zhong-Jie Lu, Kui Zhao, Jun Fan,  and Min-Li Zhou
34709-34726
Abstract  |  PDF  |  HTML  |  Order a Reprint

Digitalis use and risk of gastrointestinal cancers: A nationwide population-based cohort study

Digitalis use and risk of gastrointestinal cancers: A nationwide population-based cohort study

https://doi.org/10.18632/oncotarget.16151

Shao-Hua Xie, Tomas Jernberg, Fredrik Mattsson,  and Jesper Lagergren
34727-34735
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The SCLtTAxBCR-ABL transgenic mouse model closely reflects the differential effects of dasatinib on normal and malignant hematopoiesis in chronic phase-CML patients

The SCLtTAxBCR-ABL transgenic mouse model closely reflects the differential effects of dasatinib on normal and malignant hematopoiesis in chronic phase-CML patients

https://doi.org/10.18632/oncotarget.16152

Claudia Schubert, Nicolas Chatain, Till Braunschweig, Mirle Schemionek, Kristina Feldberg, Melanie Hoffmann, Olli Dufva, Satu Mustjoki, Tim H. Brümmendorf,  and Steffen Koschmieder
34736-34749
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GATA3 and TRPS1 are distinct biomarkers and prognostic factors in breast cancer: database mining for GATA family members in malignancies

GATA3 and TRPS1 are distinct biomarkers and prognostic factors in breast cancer: database mining for GATA family members in malignancies

https://doi.org/10.18632/oncotarget.16160

Hao-Yu Lin, De Zeng, Yuan-Ke Liang, Xiao-Long Wei,  and Chun-Fa Chen
34750-34761
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Factors affecting the loss of MED12-mutated leiomyoma cells during in vitro growth

Factors affecting the loss of MED12-mutated leiomyoma cells during in vitro growth

https://doi.org/10.18632/oncotarget.16711

Jeannine Bloch, Carsten Holzmann, Dirk Koczan, Burkhard Maria Helmke,  and Jörn Bullerdiek
34762-34772
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Cysteinyl leukotriene receptor 1 facilitates tumorigenesis in a mouse model of colitis-associated colon cancer

Cysteinyl leukotriene receptor 1 facilitates tumorigenesis in a mouse model of colitis-associated colon cancer

https://doi.org/10.18632/oncotarget.16718

Janina Osman, Sayeh Savari, Naveen Kumar Chandrashekar, Kishan Bellamkonda, Desiree Douglas,  and Anita Sjölander
34773-34786
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Development of new prognostic model based on pretreatment βLRI and LLRI for stage IE/IIE upper aerodigestive tract ENKTL, nasal type

Development of new prognostic model based on pretreatment βLRI and LLRI for stage IE/IIE upper aerodigestive tract ENKTL, nasal type

https://doi.org/10.18632/oncotarget.16720

Wumin Dai, Bo Jia, Jianliang Yang, Shengyu Zhou, Peng Liu, Xiaohui He, Yan Qin, Lin Gui, Changgong Zhang, Xiaohong Han, Yan Sun,  and Yuankai Shi
34787-34795
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical framework for next generation sequencing based analysis of treatment predictive mutations and multiplexed gene fusion detection in non-small cell lung cancer

Clinical framework for next generation sequencing based analysis of treatment predictive mutations and multiplexed gene fusion detection in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.16276

Kajsa Ericson Lindquist, Anna Karlsson, Per Levéen, Hans Brunnström, Christel Reuterswärd, Karolina Holm, Mats Jönsson, Karin Annersten, Frida Rosengren, Karin Jirström, Jaroslaw Kosieradzki, Lars Ek, Åke Borg, Maria Planck, Göran Jönsson,  and Johan Staaf
34796-34810
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Risk of osteoporosis and pathologic fractures in cancer patients who underwent hematopoietic stem cell transplantation: a nationwide retrospective cohort study

Risk of osteoporosis and pathologic fractures in cancer patients who underwent hematopoietic stem cell transplantation: a nationwide retrospective cohort study

https://doi.org/10.18632/oncotarget.16746

Jiun-Nong Lin, Hsuan-Ju Chen, Chih-Hui Yang, Chung-Hsu Lai, Hsi-Hsun Lin, Chao-Sung Chang,  and Ji-An Liang
34811-34819
Abstract  |  PDF  |  HTML  |  Order a Reprint

Molecular and serologic markers of HPV 16 infection are associated with local recurrence in patients with oral cavity squamous cell carcinoma

Molecular and serologic markers of HPV 16 infection are associated with local recurrence in patients with oral cavity squamous cell carcinoma

https://doi.org/10.18632/oncotarget.16747

Chung-Guei Huang, Li-Ang Lee, Chun-Ta Liao, Tzu-Chen Yen, Shu-Li Yang, Yi-Chun Liu, Jung-Chin Li, Yu-Nong Gong, Chung-Jan Kang, Shiang-Fu Huang, Ku-Hao Fang, Kai-Ping Chang, Li-Yu Lee, Chuen Hsueh, Shin-Ru Shih,  and Kuo-Chien Tsao
34820-34835
Abstract  |  PDF  |  HTML  |  Order a Reprint

Peripheral zone volume ratio (PZ-ratio) is relevant with biopsy results and can increase the accuracy of current diagnostic modality

Peripheral zone volume ratio (PZ-ratio) is relevant with biopsy results and can increase the accuracy of current diagnostic modality

https://doi.org/10.18632/oncotarget.16753

Yifan Chang, Rui Chen, Qingsong Yang, Xu Gao, Chuanliang Xu, Jianping Lu,  and Yinghao Sun
34836-34843
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Multi-omics study revealing the complexity and spatial heterogeneity of tumor-infiltrating lymphocytes in primary liver carcinoma

Multi-omics study revealing the complexity and spatial heterogeneity of tumor-infiltrating lymphocytes in primary liver carcinoma

https://doi.org/10.18632/oncotarget.16758

Lijun Shi, Yang Zhang, Lin Feng, Liming Wang, Weiqi Rong, Fan Wu, Jianxiong Wu, Kaitai Zhang,  and Shujun Cheng
34844-34857
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Validation and optimization of the Ion Torrent S5 XL sequencer and Oncomine workflow for BRCA1 and BRCA2 genetic testing

Validation and optimization of the Ion Torrent S5 XL sequencer and Oncomine workflow for BRCA1 and BRCA2 genetic testing

https://doi.org/10.18632/oncotarget.16799

Saeam Shin, Yoonjung Kim, Seoung Chul Oh, Nae Yu, Seung-Tae Lee, Jong Rak Choi,  and Kyung-A Lee
34858-34866
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-509-3-5P inhibits the invasion and lymphatic metastasis by targeting PODXL and serves as a novel prognostic indicator for gastric cancer

miR-509-3-5P inhibits the invasion and lymphatic metastasis by targeting PODXL and serves as a novel prognostic indicator for gastric cancer

https://doi.org/10.18632/oncotarget.16802

Jing Zhang, Zhonglin Zhu, Jinxin Sheng, Zhilong Yu, Bin Yao, Kejian Huang, Lisheng Zhou, Zhengjun Qiu,  and Chen Huang
34867-34883
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sensitive detection of viable circulating tumor cells using a novel conditionally telomerase-selective replicating adenovirus in non-small cell lung cancer patients

Sensitive detection of viable circulating tumor cells using a novel conditionally telomerase-selective replicating adenovirus in non-small cell lung cancer patients

https://doi.org/10.18632/oncotarget.16818

Shinsaku Togo, Nobuyoshi Katagiri, Yukiko Namba, Miniwan Tulafu, Kumi Nagahama, Kotarou Kadoya, Kazuya Takamochi, Siaki Oh, Kenji Suzuki, Fuminori Sakurai, Hiroyuki Mizuguchi, Yasuo Urata,  and Kazuhisa Takahashi
34884-34895
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide-resistant glioblastoma cells

Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide-resistant glioblastoma cells

https://doi.org/10.18632/oncotarget.16820

Barbara Banelli, Antonio Daga, Alessandra Forlani, Giorgio Allemanni, Daniela Marubbi, Maria Pia Pistillo, Aldo Profumo,  and Massimo Romani
34896-34910
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Loss-of-function myostatin mutation increases insulin sensitivity and browning of white fat in Meishan pigs

Loss-of-function myostatin mutation increases insulin sensitivity and browning of white fat in Meishan pigs

https://doi.org/10.18632/oncotarget.16822

Chunbo Cai, Lili Qian, Shengwang Jiang, Youde Sun, Qingqing Wang, Dezun Ma, Gaojun Xiao, Biao Li, Shanshan Xie, Ting Gao, Yaoxing Chen, Jie Liu, Xiaorong An, Wentao Cui,  and Kui Li
34911-34922
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Better cancer specific survival in young small cell lung cancer patients especially with AJCC stage III

Better cancer specific survival in young small cell lung cancer patients especially with AJCC stage III

https://doi.org/10.18632/oncotarget.16823

Haiyong Wang, Jingze Zhang, Fang Shi, Chenyue Zhang, Qinghua Jiao,  and Hui Zhu
34923-34934
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of common immunodominant antigens of Eimeria tenella, Eimeria acervulina and Eimeria maxima by immunoproteomic analysis

Identification of common immunodominant antigens of Eimeria tenella, Eimeria acervulina and Eimeria maxima by immunoproteomic analysis

https://doi.org/10.18632/oncotarget.16824

Lianrui Liu, Xinmei Huang, Jianhua Liu, Wenyu Li, Yihong Ji, Di Tian, Lu Tian, Xinchao Yang, Lixin Xu, Ruofeng Yan, Xiangrui Li,  and Xiaokai Song
34935-34945
Abstract  |  PDF  |  HTML  |  Order a Reprint

Treatment of esophageal cancer with radiation therapy: a pan-Chinese survey of radiation oncologists

Treatment of esophageal cancer with radiation therapy: a pan-Chinese survey of radiation oncologists

https://doi.org/10.18632/oncotarget.16858

Yun Zhang, Jing Liu, Wencheng Zhang, Weiye Deng,  and Jinbo Yue
34946-34953
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Systemic inflammation response index (SIRI) predicts prognosis in hepatocellular carcinoma patients

Systemic inflammation response index (SIRI) predicts prognosis in hepatocellular carcinoma patients

https://doi.org/10.18632/oncotarget.16865

Litao Xu, Shulin Yu, Liping Zhuang, Peng Wang, Yehua Shen, Junhua Lin,  and Zhiqiang Meng
34954-34960
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circular RNA alterations are involved in resistance to avian leukosis virus subgroup-J-induced tumor formation in chickens

Circular RNA alterations are involved in resistance to avian leukosis virus subgroup-J-induced tumor formation in chickens

https://doi.org/10.18632/oncotarget.16442

Xinheng Zhang, Yiming Yan, Xiaoya Lei, Aijun Li, Huanmin Zhang, Zhenkai Dai, Xinjian Li, Weiguo Chen, Wencheng Lin, Feng Chen, Jingyun Ma,  and Qingmei Xie
34961-34970
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prospects of estrogen receptor β activation in the treatment of castration-resistant prostate cancer

Prospects of estrogen receptor β activation in the treatment of castration-resistant prostate cancer

https://doi.org/10.18632/oncotarget.16496

Julia Gehrig, Silke Kaulfuß, Hubertus Jarry, Felix Bremmer, Mark Stettner, Peter Burfeind,  and Paul Thelen
34971-34979
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dnmt1s in donor cells is a barrier to SCNT-mediated DNA methylation reprogramming in pigs

Dnmt1s in donor cells is a barrier to SCNT-mediated DNA methylation reprogramming in pigs

https://doi.org/10.18632/oncotarget.16507

Xuexiong Song, Zhonghua Liu, Hongbin He, Jianyu Wang, Huatao Li, Jingyu Li, Fangzheng Li, Zhongling Jiang,  and Yanjun Huan
34980-34991
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Monocytes, endoplasmic reticulum stress and metabolomics in dogs with multiple organ dysfunction syndrome treated by continuous venovenous hemodiafiltration

Monocytes, endoplasmic reticulum stress and metabolomics in dogs with multiple organ dysfunction syndrome treated by continuous venovenous hemodiafiltration

https://doi.org/10.18632/oncotarget.16533

Yun-Peng Xu, Xiao-Lu Sui, Ai-Sha Zhang, Lei Ye, Feng-Juan Gu,  and Ji-Hong Chen
34992-35008
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cooperative down-regulation of ribosomal protein L10 and NF-κB signaling pathway is responsible for the anti-proliferative effects by DMAPT in pancreatic cancer cells

Cooperative down-regulation of ribosomal protein L10 and NF-κB signaling pathway is responsible for the anti-proliferative effects by DMAPT in pancreatic cancer cells

https://doi.org/10.18632/oncotarget.16557

Chen Shi, Yang Wang, Yuna Guo, Yijun Chen,  and Nan Liu
35009-35018
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

BRCA1 haploinsufficiency cell-autonomously activates RANKL expression and generates denosumab-responsive breast cancer-initiating cells

BRCA1 haploinsufficiency cell-autonomously activates RANKL expression and generates denosumab-responsive breast cancer-initiating cells

https://doi.org/10.18632/oncotarget.16558

Elisabet Cuyàs, Bruna Corominas-Faja, María Muñoz-San Martín, Begoña Martin-Castillo, Ruth Lupu, Joan Brunet, Joaquim Bosch-Barrera,  and Javier A. Menendez
35019-35032
Abstract  |  PDF  |  HTML  |  Order a Reprint

A potential anti-tumor effect of leukotriene C4 through the induction of 15-hydroxyprostaglandin dehydrogenase expression in colon cancer cells

A potential anti-tumor effect of leukotriene C4 through the induction of 15-hydroxyprostaglandin dehydrogenase expression in colon cancer cells

https://doi.org/10.18632/oncotarget.16591

Lubna M. Mehdawi, Shakti Ranjan Satapathy, Annika Gustafsson, Kent Lundholm, Maria Alvarado-Kristensson,  and Anita Sjölander
35033-35047
Abstract  |  PDF  |  HTML  |  Order a Reprint

Salmonella mediated the hemagglutinating virus of Japan-envelope transfer suppresses tumor growth

Salmonella mediated the hemagglutinating virus of Japan-envelope transfer suppresses tumor growth

https://doi.org/10.18632/oncotarget.17037

Che-Hsin Lee, Tomoyuki Nishikawa,  and Yasufumi Kaneda
35048-35060
Abstract  |  PDF  |  HTML  |  Order a Reprint

Gαi3 nuclear translocation causes irradiation resistance in human glioma cells

Gαi3 nuclear translocation causes irradiation resistance in human glioma cells

https://doi.org/10.18632/oncotarget.17043

Shang Cai, Ya Li, Jin-Yu Bai, Zhi-Qing Zhang, Yin Wang, Yin-Biao Qiao, Xiao-Zhong Zhou, Bo Yang, Ye Tian,  and Cong Cao
35061-35068
Abstract  |  PDF  |  HTML  |  Order a Reprint

Near-infrared photoimmunotherapy: a comparison of light dosing schedules

Near-infrared photoimmunotherapy: a comparison of light dosing schedules

https://doi.org/10.18632/oncotarget.17047

Fusa Ogata, Tadanobu Nagaya, Yuko Nakamura, Kazuhide Sato, Shuhei Okuyama, Yasuhiro Maruoka, Peter L. Choyke,  and Hisataka Kobayashi
35069-35075
Abstract  |  PDF  |  HTML  |  Order a Reprint

Long term storage in liquid nitrogen leads to only minor phenotypic and gene expression changes in the mammary carcinoma model cell line BT474

Long term storage in liquid nitrogen leads to only minor phenotypic and gene expression changes in the mammary carcinoma model cell line BT474

https://doi.org/10.18632/oncotarget.16623

Judit Fazekas, Thomas W. Grunt, Erika Jensen-Jarolim,  and Josef Singer
35076-35087
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

NK cells and multiple myeloma-associated endothelial cells: molecular interactions and influence of IL-27

NK cells and multiple myeloma-associated endothelial cells: molecular interactions and influence of IL-27

https://doi.org/10.18632/oncotarget.17070

Alessandra Dondero, Beatrice Casu, Francesca Bellora, Angelo Vacca, Annunziata De Luisi, Maria Antonia Frassanito, Claudia Cantoni, Silvia Gaggero, Daniel Olive, Alessandro Moretta, Cristina Bottino,  and Roberta Castriconi
35088-35102
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ginkgolic acids inhibit migration in breast cancer cells by inhibition of NEMO sumoylation and NF-κB activity

Ginkgolic acids inhibit migration in breast cancer cells by inhibition of NEMO sumoylation and NF-κB activity

https://doi.org/10.18632/oncotarget.16626

Sami Hamdoun,  and Thomas Efferth
35103-35115
Abstract  |  PDF  |  HTML  |  Order a Reprint

Serum IL-33 level is a predictor of progression-free survival after chemotherapy

Serum IL-33 level is a predictor of progression-free survival after chemotherapy

https://doi.org/10.18632/oncotarget.16627

Wenwei Hu, Chen Wu, Xiaodong Li, Zhuojun Zheng, Quanqin Xie, Xu Deng, Jingting Jiang,  and Changping Wu
35116-35123
Abstract  |  PDF  |  HTML  |  Order a Reprint

Vacquinol-1 inducible cell death in glioblastoma multiforme is counter regulated by TRPM7 activity induced by exogenous ATP

Vacquinol-1 inducible cell death in glioblastoma multiforme is counter regulated by TRPM7 activity induced by exogenous ATP

https://doi.org/10.18632/oncotarget.16703

Philip Sander, Haouraa Mostafa, Ayman Soboh, Julian M. Schneider, Andrej Pala, Ann-Kathrin Baron, Barbara Moepps, C. Rainer Wirtz, Michael Georgieff,  and E. Marion Schneider
35124-35137
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Toll-like receptor 3 as an immunotherapeutic target for KRAS mutated colorectal cancer

Toll-like receptor 3 as an immunotherapeutic target for KRAS mutated colorectal cancer

https://doi.org/10.18632/oncotarget.16812

Radhashree Maitra, Titto Augustine, Yitzchak Dayan, Carol Chandy, Matthew Coffey,  and Sanjay Goel
35138-35153
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The clinical value, regulatory mechanisms, and gene network of the cancer-testis gene STK31 in pancreatic cancer

The clinical value, regulatory mechanisms, and gene network of the cancer-testis gene STK31 in pancreatic cancer

https://doi.org/10.18632/oncotarget.16814

Kai Zhang, Zipeng Lu, Yi Zhu, Lei Tian, Jingjing Zhang, Chunhua Xi, Wentao Gao, Kuirong Jiang,  and Yi Miao
35154-35164
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Serrated adenocarcinoma morphology in colorectal mucinous adenocarcinoma is associated with improved patient survival

Serrated adenocarcinoma morphology in colorectal mucinous adenocarcinoma is associated with improved patient survival

https://doi.org/10.18632/oncotarget.16815

Chung-Ta Lee, Yu-Chuan Huang, Liang-Yi Hung, Nan-Haw Chow, Pei-Fang Su, Chung-Liang Ho, Hung-Wen Tsai, Yi-Lin Chen, Shao-Chieh Lin, Bo-Wen Lin, Peng-Chan Lin,  and Jenq-Chang Lee
35165-35175
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeted next generation sequencing identified novel mutations in RPGRIP1 associated with both retinitis pigmentosa and Leber's congenital amaurosis in unrelated Chinese patients

Targeted next generation sequencing identified novel mutations in RPGRIP1 associated with both retinitis pigmentosa and Leber's congenital amaurosis in unrelated Chinese patients

https://doi.org/10.18632/oncotarget.17052

Hui Huang, Ying Wang, Huishuang Chen, Yanhua Chen, Jing Wu, Pei-Wen Chiang, Ning Fan, Yan Su, Jianlian Deng, Dongna Chen, Yang Li, Xinxin Zhang, Mengxin Zhang, Shengran Liang, Santasree Banerjee, Ming Qi,  and Xuyang Liu
35176-35183
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Apoptosis-related microRNA-145-5p enhances the effects of pheophorbide a-based photodynamic therapy in oral cancer

Apoptosis-related microRNA-145-5p enhances the effects of pheophorbide a-based photodynamic therapy in oral cancer

https://doi.org/10.18632/oncotarget.17059

Sook Moon, Do Kyeong Kim,  and Jin Kim
35184-35192
Abstract  |  PDF  |  HTML  |  Order a Reprint

Predictive blood plasma biomarkers for EGFR inhibitor-induced skin rash

Predictive blood plasma biomarkers for EGFR inhibitor-induced skin rash

https://doi.org/10.18632/oncotarget.17060

Vivien Hichert, Catharina Scholl, Michael Steffens, Tanusree Paul, Christian Schumann, Stefan Rüdiger, Stefan Boeck, Volker Heinemann, Volker Kächele, Thomas Seufferlein,  and Julia Stingl
35193-35204
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeting autophagic cancer stem-cells to reverse chemoresistance in human triple negative breast cancer

Targeting autophagic cancer stem-cells to reverse chemoresistance in human triple negative breast cancer

https://doi.org/10.18632/oncotarget.16925

Guilhem Bousquet, Morad El Bouchtaoui, Tan Sophie, Christophe Leboeuf, Cédric de Bazelaire, Philippe Ratajczak, Sylvie Giacchetti, Anne de Roquancourt, Philippe Bertheau, Laurence Verneuil, Jean-Paul Feugeas, Marc Espié,  and Anne Janin
35205-35221
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Meta-Analysis

Accuracy of the urine UCA1 for diagnosis of bladder cancer: a meta-analysis

Accuracy of the urine UCA1 for diagnosis of bladder cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.16473

Xiangrong Cui, Xuan Jing, Chunlan Long, Qin Yi, Jie Tian,  and Jing Zhu
35222-35233
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Altered long non-coding RNAs predict worse outcome in osteosarcoma patients: evidence from a meta-analysis

Altered long non-coding RNAs predict worse outcome in osteosarcoma patients: evidence from a meta-analysis

https://doi.org/10.18632/oncotarget.16470

Yanliang Yang, Shunli Wang,  and Teng Li
35234-35243
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

High NUCB2 expression level represents an independent negative prognostic factor in Chinese cohorts of non-metastatic clear cell renal cell carcinoma patients

High NUCB2 expression level represents an independent negative prognostic factor in Chinese cohorts of non-metastatic clear cell renal cell carcinoma patients

https://doi.org/10.18632/oncotarget.12961

Hangcheng Fu, Yu Zhu, Yiwei Wang, Zheng Liu, Junyu Zhang, Zewei Wang, Huyang Xie, Bo Dai, Jiejie Xu,  and Dingwei Ye
35244-35254
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Serum monocyte fraction of white blood cells is increased in patients with high Gleason score prostate cancer

Serum monocyte fraction of white blood cells is increased in patients with high Gleason score prostate cancer

https://doi.org/10.18632/oncotarget.13052

Takuji Hayashi, Kazutoshi Fujita, Go Tanigawa, Atsunari Kawashima, Akira Nagahara, Takeshi Ujike, Motohide Uemura, Tetsuya Takao, Seiji Yamaguchi,  and Norio Nonomura
35255-35261
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Greater efficacy of intracavitary infusion of bevacizumab compared to traditional local treatments for patients with malignant cavity serous effusion

Greater efficacy of intracavitary infusion of bevacizumab compared to traditional local treatments for patients with malignant cavity serous effusion

https://doi.org/10.18632/oncotarget.13064

Dawei Chen, Xinyu Song, Fang Shi, Hui Zhu, Haiyong Wang, Nasha Zhang, Yan Zhang, Li Kong,  and Jinming Yu
35262-35271
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dosimetric superiority of flattening filter free beams for single-fraction stereotactic radiosurgery in single brain metastasis

Dosimetric superiority of flattening filter free beams for single-fraction stereotactic radiosurgery in single brain metastasis

https://doi.org/10.18632/oncotarget.13085

Youqun Lai, Shanyu Chen, Changdong Xu, Liwan Shi, Lirong Fu, Huiming Ha, Qin Lin,  and Zhen Zhang
35272-35279
Abstract  |  PDF  |  HTML  |  Order a Reprint

Efficacy of postoperative radiotherapy in patients with pathological stage N2 epidermal growth factor receptor wild type adenocarcinoma and squamous cell carcinoma lung cancer

Efficacy of postoperative radiotherapy in patients with pathological stage N2 epidermal growth factor receptor wild type adenocarcinoma and squamous cell carcinoma lung cancer

https://doi.org/10.18632/oncotarget.13257

Yen-Kuang Lin, Han-Lin Hsu, Wei-Cheng Lin, Jer-Hwa Chang, Yw-Chun Chang, Chia-Lun Chang, Kevin Sheng-Po Yuan, Alexander T.H. Wu,  and Szu-Yuan Wu
35280-35288
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical validation of prospective liquid biopsy monitoring in patients with wild-type RAS metastatic colorectal cancer treated with FOLFIRI-cetuximab

Clinical validation of prospective liquid biopsy monitoring in patients with wild-type RAS metastatic colorectal cancer treated with FOLFIRI-cetuximab

https://doi.org/10.18632/oncotarget.13311

Rodrigo A. Toledo, Antonio Cubillo, Estela Vega, Elena Garralda, Rafael Alvarez, Lisardo U. de la Varga, Jesús R. Pascual, Gema Sánchez, Francesca Sarno, Susana H. Prieto, Sofía Perea, Pedro P. Lopéz-Casas, Fernando López-Ríos,  and Manuel Hidalgo
35289-35300
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preoperative platelet to lymphocyte and neutrophil to lymphocyte ratios are independent prognostic factors for patients undergoing lung cancer radical surgery: A single institutional cohort study

Preoperative platelet to lymphocyte and neutrophil to lymphocyte ratios are independent prognostic factors for patients undergoing lung cancer radical surgery: A single institutional cohort study

https://doi.org/10.18632/oncotarget.13312

Haidan Lan, Leng Zhou, Dongmei Chi, Qinghua Zhou, XiaoJun Tang, Daxing Zhu, Jianmin Yue,  and Bin Liu
35301-35310
Abstract  |  PDF  |  HTML  |  Order a Reprint

A nomogram to predict the probability of axillary lymph node metastasis in female patients with breast cancer in China: A nationwide, multicenter, 10-year epidemiological study

A nomogram to predict the probability of axillary lymph node metastasis in female patients with breast cancer in China: A nationwide, multicenter, 10-year epidemiological study

https://doi.org/10.18632/oncotarget.13330

Jian Zhang, Xiao Li, Rong Huang, Wei-Liang Feng, Ya-Nan Kong, Feng Xu, Lin Zhao, Qing-Kun Song, Jing Li, Bao-Ning Zhang, Jin-Hu Fan, You-Lin Qiao, Xiao-Ming Xie, Shan Zheng, Jian-Jun He,  and Ke Wang
35311-35325
Abstract  |  PDF  |  HTML  |  Order a Reprint

Combination epigenetic therapy in metastatic colorectal cancer (mCRC) with subcutaneous 5-azacitidine and entinostat: a phase 2 consortium/stand Up 2 cancer study

Combination epigenetic therapy in metastatic colorectal cancer (mCRC) with subcutaneous 5-azacitidine and entinostat: a phase 2 consortium/stand Up 2 cancer study

https://doi.org/10.18632/oncotarget.15108

Nilofer S. Azad, Anthony el-Khoueiry, Jun Yin, Ann L. Oberg, Patrick Flynn, Douglas Adkins, Anup Sharma, Daniel J. Weisenberger, Thomas Brown, Prakriti Medvari, Peter A. Jones, Hariharan Easwaran, Ihab Kamel, Nathan Bahary, George Kim, Joel Picus, Henry C. Pitot, Charles Erlichman, Ross Donehower, Hui Shen, Peter W. Laird, Richard Piekarz, Stephen Baylin,  and Nita Ahuja
35326-35338
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeted sequencing of tonsillar and base of tongue cancer and human papillomavirus positive unknown primary of the head and neck reveals prognostic effects of mutated FGFR3

Targeted sequencing of tonsillar and base of tongue cancer and human papillomavirus positive unknown primary of the head and neck reveals prognostic effects of mutated FGFR3

https://doi.org/10.18632/oncotarget.15240

Cinzia Bersani, Lars Sivars, Linnea Haeggblom, Sebastian DiLorenzo, Michael Mints, Andreas Ährlund-Richter, Nikolaos Tertipis, Eva Munck-Wikland, Anders Näsman, Torbjörn Ramqvist,  and Tina Dalianis
35339-35350
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reviews

Cancer stem cells (CSCs), cervical CSCs and targeted therapies

Cancer stem cells (CSCs), cervical CSCs and targeted therapies

https://doi.org/10.18632/oncotarget.10169

Ruixia Huang,  and Einar K. Rofstad
35351-35367
Abstract  |  PDF  |  HTML  |  Order a Reprint

Should surgery be conducted for small nonfunctioning pancreatic neuroendocrine tumors: a systematic review

Should surgery be conducted for small nonfunctioning pancreatic neuroendocrine tumors: a systematic review

https://doi.org/10.18632/oncotarget.15685

Jingfei Guo, Jianjun Zhao, Xinyu Bi, Zhiyu Li, Zhen Huang, Yefan Zhang, Jianqiang Cai,  and Hong Zhao
35368-35375
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epithelial-mesenchymal transition in prostate cancer: an overview

Epithelial-mesenchymal transition in prostate cancer: an overview

https://doi.org/10.18632/oncotarget.15686

Micaela Montanari, Sabrina Rossetti, Carla Cavaliere, Carmine D’Aniello, Maria Gabriella Malzone, Daniela Vanacore, Rossella Di Franco, Elvira La Mantia, Gelsomina Iovane, Raffaele Piscitelli, Raffaele Muscariello, Massimiliano Berretta, Sisto Perdonà, Paolo Muto, Gerardo Botti, Attilio Antonio Montano Bianchi, Bianca Maria Veneziani,  and Gaetano Facchini
35376-35389
Abstract  |  PDF  |  HTML  |  Order a Reprint

Fine tuning of vitamin D receptor (VDR) activity by post-transcriptional and post-translational modifications

Fine tuning of vitamin D receptor (VDR) activity by post-transcriptional and post-translational modifications

https://doi.org/10.18632/oncotarget.15697

Ondrej Zenata,  and Radim Vrzal
35390-35402
Abstract  |  PDF  |  HTML  |  Order a Reprint

Genetic factors associated with risk of metabolic syndrome and hepatocellular carcinoma

Genetic factors associated with risk of metabolic syndrome and hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.15893

Ranran Tang, Heng Liu, Yingdi Yuan, Kaipeng Xie, Pengfei Xu, Xiaoyun Liu,  and Juan Wen
35403-35411
Abstract  |  PDF  |  HTML  |  Order a Reprint

Sulforaphane for the chemoprevention of bladder cancer: molecular mechanism targeted approach

Sulforaphane for the chemoprevention of bladder cancer: molecular mechanism targeted approach

https://doi.org/10.18632/oncotarget.16015

Andrew Leone, Gregory Diorio, Wade Sexton, Michael Schell, Mark Alexandrow, Jed W. Fahey,  and Nagi B. Kumar
35412-35424
Abstract  |  PDF  |  HTML  |  Order a Reprint

Impact of metformin on C-reactive protein levels in women with polycystic ovary syndrome: a meta-analysis

Impact of metformin on C-reactive protein levels in women with polycystic ovary syndrome: a meta-analysis

https://doi.org/10.18632/oncotarget.16019

Yong Chen, Meng Li, Hongli Deng, Sheying Wang, Lihua Chen, Ningsha Li, Dan Xu,  and Qiguang Wang
35425-35434
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The importance of the genomic landscape in Waldenström’s Macroglobulinemia for targeted therapeutical interventions

The importance of the genomic landscape in Waldenström’s Macroglobulinemia for targeted therapeutical interventions

https://doi.org/10.18632/oncotarget.16130

Antonio Sacco, Adriano Fenotti, Loredana Affò, Stefano Bazzana, Domenico Russo, Marco Presta, Michele Malagola, Antonella Anastasia, Marina Motta, Christopher J. Patterson, Giuseppe Rossi, Luisa Imberti, Steven P. Treon, Irene M. Ghobrial,  and Aldo M. Roccaro
35435-35444
Abstract  |  PDF  |  HTML  |  Order a Reprint

Pathogenesis of ETV6/RUNX1-positive childhood acute lymphoblastic leukemia and mechanisms underlying its relapse

Pathogenesis of ETV6/RUNX1-positive childhood acute lymphoblastic leukemia and mechanisms underlying its relapse

https://doi.org/10.18632/oncotarget.16367

Congcong Sun, Lixian Chang,  and Xiaofan Zhu
35445-35459
Abstract  |  PDF  |  HTML  |  Order a Reprint

Metabolomics for biomarker discovery in the diagnosis, prognosis, survival and recurrence of colorectal cancer: a systematic review

Metabolomics for biomarker discovery in the diagnosis, prognosis, survival and recurrence of colorectal cancer: a systematic review

https://doi.org/10.18632/oncotarget.16727

Fan Zhang, Yuanyuan Zhang, Weiwei Zhao, Kui Deng, Zhuozhong Wang, Chunyan Yang, Libing Ma, Margarita S. Openkova, Yan Hou,  and Kang Li
35460-35472
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Case Reports

Primary Sjögren’s syndrome with diffuse cystic lung changes developed systemic lupus erythematosus: a case report and literature review

Primary Sjögren’s syndrome with diffuse cystic lung changes developed systemic lupus erythematosus: a case report and literature review

https://doi.org/10.18632/oncotarget.16010

Xiao Liu, Hao Li, Yunhong Yin, Dedong Ma,  and Yiqing Qu
35473-35479
Abstract  |  PDF  |  HTML  |  Order a Reprint

Corrections

Correction: Novel leptin OB3 peptide-induced signaling and progression in thyroid cancers: Comparison with leptin

Correction: Novel leptin OB3 peptide-induced signaling and progression in thyroid cancers: Comparison with leptin

https://doi.org/10.18632/oncotarget.18067

Yu-Chen SH Yang, Yu-Tang Chin, Meng-Ti Hsieh, Hsuan-Yu Lai, Chien-Chih Ke, Dana R. Crawford, Oscar K. Lee, Earl Fu, Shaker A. Mousa, Patricia Grasso, Leroy F. Liu, Heng-Yu Chang, Heng-Yuan Tang, Hung-Yun Lin,  and Paul J. Davis
35480-35480
Correction  |  PDF

Correction: Quantitative ultrasound assessment of breast tumor response to chemotherapy using a multi-parameter approach

Correction: Quantitative ultrasound assessment of breast tumor response to chemotherapy using a multi-parameter approach

https://doi.org/10.18632/oncotarget.18068

Hadi Tadayyon, Lakshmanan Sannachi, Mehrdad Gangeh, Ali Sadeghi-Naini, William Tran, Maureen E. Trudeau, Kathleen Pritchard, Sonal Ghandi, Sunil Verma,  and Gregory J. Czarnota
35481-35481
Correction  |  PDF


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