Oncotarget

Vol 8, No 16

April 18, 2017

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About The Cover

The cover for issue 16 of Oncotarget features Figure 1, "XIAP and NFκB expression in tumor emboli in IBC patient samples," from Arora, et al.

Table of Contents

News

Further rationale for optimal combined modality treatments

Further rationale for optimal combined modality treatments

DOI: 10.18632/oncotarget.16117

Robert J. Griffin, Ruud P.M. Dings,  and Issam Makhoul
25831-25832
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Realistic modeling of tumor cells

Realistic modeling of tumor cells

DOI: 10.18632/oncotarget.17122

Kenneth L. van Golen
25833-25834
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A target of potential RELAvance in inflammatory breast cancer

A target of potential RELAvance in inflammatory breast cancer

DOI: 10.18632/oncotarget.17109

Bedrich L. Eckhardt,  and Naoto T. Ueno
25835-25836
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Priority Research Papers

Tumorigenesis promotes Mdm4-S overexpression

Tumorigenesis promotes Mdm4-S overexpression

DOI: 10.18632/oncotarget.15552

Vinod Pant, Connie A. Larsson, Neeraj Aryal, Shunbin Xiong, M. James You, Alfonso Quintas-Cardama,  and Guillermina Lozano
25837-25847
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Inflammatory breast cancer tumor emboli express high levels of anti-apoptotic proteins: use of a quantitative high content and high-throughput 3D IBC spheroid assay to identify targeting strategies

Inflammatory breast cancer tumor emboli express high levels of anti-apoptotic proteins: use of a quantitative high content and high-throughput 3D IBC spheroid assay to identify targeting strategies

DOI: 10.18632/oncotarget.15667

Jay Arora, Scott J. Sauer, Michael Tarpley, Peter Vermeulen, Charlotte Rypens, Steven Van Laere, Kevin P. Williams, Gayathri R. Devi,  and Mark W. Dewhirst
25848-25863
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Research Papers: Chromosome

BMPR1B mutation causes Pierre Robin sequence

BMPR1B mutation causes Pierre Robin sequence

DOI: 10.18632/oncotarget.16531

Yongjia Yang, Jianying Yuan, Xu Yao, Rong Zhang, Hui Yang, Rui Zhao, Jihong Guo, Ke Jin, Haibo Mei, Yongqi Luo, Liu Zhao, Ming Tu,  and Yimin Zhu
25864-25871
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Research Papers: Neuroscience

Specific amplifications and copy number decreases during human neural stem cells differentiation towards astrocytes, neurons and oligodendrocytes

Specific amplifications and copy number decreases during human neural stem cells differentiation towards astrocytes, neurons and oligodendrocytes

DOI: 10.18632/oncotarget.15980

Ulrike Fischer, Ella Kim, Andreas Keller,  and Eckart Meese
25872-25884
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Research Papers

HIF-1α activates hypoxia-induced BCL-9 expression in human colorectal cancer cells

HIF-1α activates hypoxia-induced BCL-9 expression in human colorectal cancer cells

DOI: 10.18632/oncotarget.8834

Zhen Tan, Quan Huang, Jia Zang, Shi-Feng Teng, Tian-Rui Chen, Hai-Feng Wei, Dian-Wen Song, Tie-Long Liu, Xing-Hai Yang, Chuan-Gang Fu, Zhi-Qian Hu, Wang Zhou, Wang-Jun Yan,  and Jian-Ru Xiao
25885-25896
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Ginsenoside-Rb1 targets chemotherapy-resistant ovarian cancer stem cells via simultaneous inhibition of Wnt/β-catenin signaling and epithelial-to-mesenchymal transition

Ginsenoside-Rb1 targets chemotherapy-resistant ovarian cancer stem cells via simultaneous inhibition of Wnt/β-catenin signaling and epithelial-to-mesenchymal transition

DOI: 10.18632/oncotarget.13071

Shan Deng, Chris Kong Chu Wong, Hung-Cheng Lai,  and Alice Sze Tsai Wong
25897-25914
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Tissue Factor promotes breast cancer stem cell activity in vitro

Tissue Factor promotes breast cancer stem cell activity in vitro

DOI: 10.18632/oncotarget.13928

Hudhaifah Shaker, Hannah Harrison, Robert Clarke, Goran Landberg, Nigel J. Bundred, Henri H. Versteeg,  and Cliona C. Kirwan
25915-25927
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Metabolic heterogeneity signature of primary treatment-naïve prostate cancer

Metabolic heterogeneity signature of primary treatment-naïve prostate cancer

DOI: 10.18632/oncotarget.15237

Dong Lin, Susan L. Ettinger, Sifeng Qu, Hui Xue, Noushin Nabavi, Stephen Yiu Chuen Choi, Robert H. Bell, Fan Mo, Anne M. Haegert, Peter W. Gout, Neil Fleshner, Martin E. Gleave, Michael Pollak, Colin C. Collins,  and Yuzhuo Wang
25928-25941
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The long noncoding RNA, treRNA, decreases DNA damage and is associated with poor response to chemotherapy in chronic lymphocytic leukemia

The long noncoding RNA, treRNA, decreases DNA damage and is associated with poor response to chemotherapy in chronic lymphocytic leukemia

DOI: 10.18632/oncotarget.15401

Cecelia R. Miller, Amy S. Ruppert, Sydney Fobare, Timothy L. Chen, Chaomei Liu, Amy Lehman, James S. Blachly, Xiaoli Zhang, David M. Lucas, Michael R. Grever, Martin S. Tallman, Ian W. Flinn, Laura Z. Rassenti, Thomas J. Kipps, Deepa Sampath, Kevin R. Coombes,  and Erin K. Hertlein
25942-25954
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Prevention of tumor seeding during needle biopsy by chemotherapeutic-releasing gelatin sticks

Prevention of tumor seeding during needle biopsy by chemotherapeutic-releasing gelatin sticks

DOI: 10.18632/oncotarget.15427

Ren-Yuan Bai, Verena Staedtke, Xuewei Xia,  and Gregory J. Riggins
25955-25962
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MicroRNA regulation of progesterone receptor in breast cancer

MicroRNA regulation of progesterone receptor in breast cancer

DOI: 10.18632/oncotarget.15657

Avital Gilam, Ayelet Shai, Itamar Ashkenazi, Liat Appel Sarid, Assi Drobot, Amitai Bickel,  and Noam Shomron
25963-25976
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Over-expression of ASIC1a promotes proliferation via activation of the β-catenin/LEF-TCF axis and is associated with disease outcome in liver cancer

Over-expression of ASIC1a promotes proliferation via activation of the β-catenin/LEF-TCF axis and is associated with disease outcome in liver cancer

DOI: 10.18632/oncotarget.10774

Cheng Jin, Feng-Lai Yuan, Yuan-Long Gu, Xia Li, Min-Feng Liu, Xiao-Min Shen, Bo Liu,  and Mao-Qun Zhu
25977-25988
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CMV70-3P miRNA contributes to the CMV mediated glioma stemness and represents a target for glioma experimental therapy

CMV70-3P miRNA contributes to the CMV mediated glioma stemness and represents a target for glioma experimental therapy

DOI: 10.18632/oncotarget.11175

Ilya V. Ulasov, Natalya V. Kaverina, Dhimankrishna Ghosh, Marya A. Baryshnikova, Zaira G. Kadagidze, Apollon I. Karseladze, Anatoly Y. Baryshnikov,  and Charles S. Cobbs
25989-25999
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Stathmin overexpression is associated with growth, invasion and metastasis of lung adenocarcinoma

Stathmin overexpression is associated with growth, invasion and metastasis of lung adenocarcinoma

DOI: 10.18632/oncotarget.11006

Lin Yurong, Rong Biaoxue, Li Wei, Ming Zongjuan, Shi Hongyang, Fang Ping, Gao Wenlong, Yang Shuanying,  and Li Zongfang
26000-26012
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C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cells

C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cells

DOI: 10.18632/oncotarget.14847

Jamie D. Gardiner, Lisa M. Abegglen, Xiaomeng Huang, Bryce E. Carter, Elizabeth A. Schackmann, Marcus Stucki, Christian N. Paxton, R. Lor Randall, James F. Amatruda, Angelica R. Putnam, Heinrich Kovar, Stephen L. Lessnick,  and Joshua D. Schiffman
26013-26026
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The CRISPR/Cas9 system efficiently reverts the tumorigenic ability of BCR/ABL in vitro and in a xenograft model of chronic myeloid leukemia

The CRISPR/Cas9 system efficiently reverts the tumorigenic ability of BCR/ABL in vitro and in a xenograft model of chronic myeloid leukemia

DOI: 10.18632/oncotarget.15215

Ignacio García-Tuñón, María Hernández-Sánchez, José Luis Ordoñez, Veronica Alonso-Pérez, Miguel Álamo-Quijada, Rocio Benito, Carmen Guerrero, Jesús María Hernández-Rivas,  and Manuel Sánchez-Martín
26027-26040
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Proteomic analysis of laser capture microdissected focal lesions in a rat model of progenitor marker-positive hepatocellular carcinoma

Proteomic analysis of laser capture microdissected focal lesions in a rat model of progenitor marker-positive hepatocellular carcinoma

DOI: 10.18632/oncotarget.15219

Adeola O. Adebayo Michael, Nagib Ahsan, Valerie Zabala, Heather Francois-Vaughan, Stephanie Post, Kate E. Brilliant, Arthur R. Salomon, Jennifer A. Sanders,  and Philip A. Gruppuso
26041-26056
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Incorporation of the number of positive lymph nodes leads to better prognostic discrimination of node-positive early stage cervical cancer

Incorporation of the number of positive lymph nodes leads to better prognostic discrimination of node-positive early stage cervical cancer

DOI: 10.18632/oncotarget.15220

Juan Zhou, San-Gang Wu, Jia-Yuan Sun, Xu-Lin Liao, Feng-Yan Li, Huan-Xin Lin, Li-Chao Yang,  and Zhen-Yu He
26057-26065
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Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer

Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer

DOI: 10.18632/oncotarget.15257

Joan Chang, Morghan C. Lucas, Lidia E. Leonte, Marc Garcia-Montolio, Lukram Babloo Singh, Alison D. Findlay, Mandar Deodhar, Jonathan S. Foot, Wolfgang Jarolimek, Paul Timpson, Janine T. Erler,  and Thomas R. Cox
26066-26078
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Long non-coding RNA PTENP1 functions as a ceRNA to modulate PTEN level by decoying miR-106b and miR-93 in gastric cancer

Long non-coding RNA PTENP1 functions as a ceRNA to modulate PTEN level by decoying miR-106b and miR-93 in gastric cancer

DOI: 10.18632/oncotarget.15317

Rupeng Zhang, Yuenan Guo, Zhenchi Ma, Gang Ma, Qiang Xue, Fangxuan Li,  and Liren Liu
26079-26089
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Upregulation of long non-coding RNA PlncRNA-1 promotes proliferation and induces epithelial-mesenchymal transition in prostate cancer

Upregulation of long non-coding RNA PlncRNA-1 promotes proliferation and induces epithelial-mesenchymal transition in prostate cancer

DOI: 10.18632/oncotarget.15318

Yang Jin, Zilian Cui, Xudong Li, Xunbo Jin,  and Jian Peng
26090-26099
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Association between echocardiographic structural parameters and body weight in Wistar rats

Association between echocardiographic structural parameters and body weight in Wistar rats

DOI: 10.18632/oncotarget.15320

Silvio A. Oliveira-Junior, Paula F. Martinez, William Y.C. Fan, Bruno T. Nakatani, Luana U. Pagan, Carlos R. Padovani, Antonio C. Cicogna, Marina P. Okoshi,  and Katashi Okoshi
26100-26105
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Fluorescence in situ hybridization status of voided urine predicts invasive and high-grade upper tract urothelial carcinoma

Fluorescence in situ hybridization status of voided urine predicts invasive and high-grade upper tract urothelial carcinoma

DOI: 10.18632/oncotarget.15344

Xiaohong Su, Han Hao, Xuesong Li, Zhisong He, Kan Gong, Cuijian Zhang, Lin Cai, Qian Zhang, Lin Yao, Yi Ding, Yanqing Gong, Dong Fang, Zheng Zhang,  and Liqun Zhou
26106-26111
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Expression of MET in circulating tumor cells correlates with expression in tumor tissue from advanced-stage lung cancer patients

Expression of MET in circulating tumor cells correlates with expression in tumor tissue from advanced-stage lung cancer patients

DOI: 10.18632/oncotarget.15345

Marius Ilie, Edith Szafer-Glusman, Véronique Hofman, Elodie Long-Mira, Rebecca Suttmann, Walter Darbonne, Catherine Butori, Salomé Lalvée, Julien Fayada, Eric Selva, Wei Yu, Charles-Hugo Marquette, David S. Shames, Elizabeth Punnoose,  and Paul Hofman
26112-26121
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Immunohistochemical Ki67 after short-term hormone therapy identifies low-risk breast cancers as reliably as genomic markers

Immunohistochemical Ki67 after short-term hormone therapy identifies low-risk breast cancers as reliably as genomic markers

DOI: 10.18632/oncotarget.15385

Takayuki Iwamoto, Toyomasa Katagiri, Naoki Niikura, Yuichiro Miyoshi, Mariko Kochi, Tomohiro Nogami, Tadahiko Shien, Takayuki Motoki, Naruto Taira, Masako Omori, Yutaka Tokuda, Toshiyoshi Fujiwara, Hiroyoshi Doihara, Balazs Gyorffy,  and Junji Matsuoka
26122-26128
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ZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia

ZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia

DOI: 10.18632/oncotarget.15387

Giuseppe Germano, Giulia Morello, Sanja Aveic, Marica Pinazza, Sonia Minuzzo, Chiara Frasson, Luca Persano, Paolo Bonvini, Giampietro Viola, Silvia Bresolin, Claudia Tregnago, Maddalena Paganin, Martina Pigazzi, Stefano Indraccolo,  and Giuseppe Basso
26129-26141
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Increased reactive oxygen species levels cause ER stress and cytotoxicity in andrographolide treated colon cancer cells

Increased reactive oxygen species levels cause ER stress and cytotoxicity in andrographolide treated colon cancer cells

DOI: 10.18632/oncotarget.15393

Aditi Banerjee, Vivekjyoti Banerjee, Steven Czinn,  and Thomas Blanchard
26142-26153
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C-terminal binding protein-2 promotes cell proliferation and migration in breast cancer via suppression of p16INK4A

C-terminal binding protein-2 promotes cell proliferation and migration in breast cancer via suppression of p16INK4A

DOI: 10.18632/oncotarget.15402

Xiaojing Yang, Yi Sun, Hongling Li, Yuhui Shao, Depeng Zhao, Weiwei Yu,  and Jie Fu
26154-26168
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Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer

Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer

DOI: 10.18632/oncotarget.15410

Helga Weber, José R. Valbuena, Mustafa A. Barbhuiya, Stefan Stein, Hana Kunkel, Patricia García, Carolina Bizama, Ismael Riquelme, Jaime A. Espinoza, Stephen E. Kurtz, Jeffrey W. Tyner, Juan Francisco Calderon, Alejandro H. Corvalán, Manuel Grez, Akhilesh Pandey, Pamela Leal-Rojas,  and Juan C. Roa
26169-26184
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Whole genome sequencing of matched tumor, adjacent non-tumor tissues and corresponding normal blood samples of hepatocellular carcinoma patients revealed dynamic changes of the mutations profiles during hepatocarcinogenesis

Whole genome sequencing of matched tumor, adjacent non-tumor tissues and corresponding normal blood samples of hepatocellular carcinoma patients revealed dynamic changes of the mutations profiles during hepatocarcinogenesis

DOI: 10.18632/oncotarget.15428

Ruifang Mao, Jie Liu, Guanfeng Liu, Shanshan Jin, Qingzhong Xue, Liang Ma, Yan Fu, Na Zhao, Jinliang Xing, Lanjuan Li, Yunqing Qiu,  and Biaoyang Lin
26185-26199
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Glucose deprivation elicits phenotypic plasticity via ZEB1-mediated expression of NNMT

Glucose deprivation elicits phenotypic plasticity via ZEB1-mediated expression of NNMT

DOI: 10.18632/oncotarget.15429

Justyna Kanska, Paul-Joseph P. Aspuria, Barbie Taylor-Harding, Lindsay Spurka, Vincent Funari, Sandra Orsulic, Beth Y. Karlan,  and W. Ruprecht Wiedemeyer
26200-26220
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Tumor biology, clinicopathological characteristics and prognosis of screen detected T1 invasive non-palpable breast cancer in asymptomatic Chinese women (2001–2014)

Tumor biology, clinicopathological characteristics and prognosis of screen detected T1 invasive non-palpable breast cancer in asymptomatic Chinese women (2001–2014)

DOI: 10.18632/oncotarget.15431

Bo Pan, Ru Yao, Yi-Dong Zhou, Qing-Li Zhu, Jie Shi, Qian-Qian Xu, Chang-Jun Wang, Shan-Shan You, Feng Mao, Yan Lin, Song-Jie Shen, Zhi-Yong Liang, Yu-Xin Jiang,  and Qiang Sun
26221-26230
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reduced NOV expression correlates with disease progression in colorectal cancer and is associated with survival, invasion and chemoresistance of cancer cells

Reduced NOV expression correlates with disease progression in colorectal cancer and is associated with survival, invasion and chemoresistance of cancer cells

DOI: 10.18632/oncotarget.15439

Jun Li, Lin Ye, Ping-Hui Sun, Fei Zheng, Fiona Ruge, Lucy K. Satherley, Yi Feng, Huishan Zhao, Guifang Du, Tingting Wang, Yao Yang, Xuemei Ma, Shan Cheng, Xiaomei Yang, Hefen Yu, Xu Teng, Yang Si, Zhongtao Zhang,  and Wen G. Jiang
26231-26244
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Retinoic acid receptor alpha drives cell cycle progression and is associated with increased sensitivity to retinoids in T-cell lymphoma

Retinoic acid receptor alpha drives cell cycle progression and is associated with increased sensitivity to retinoids in T-cell lymphoma

DOI: 10.18632/oncotarget.15441

Xueju Wang, Surendra Dasari, Grzegorz S. Nowakowski, Konstantinos N. Lazaridis, Eric D. Wieben, Marshall E. Kadin, Andrew L. Feldman,  and Rebecca L. Boddicker
26245-26255
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combination epidermal growth factor receptor variant III peptide-pulsed dendritic cell vaccine with miR-326 results in enhanced killing on EGFRvIII-positive cells

Combination epidermal growth factor receptor variant III peptide-pulsed dendritic cell vaccine with miR-326 results in enhanced killing on EGFRvIII-positive cells

DOI: 10.18632/oncotarget.15445

Jianlong Li, Feng Wang, Guangzhi Wang, Ying Sun, Jinquan Cai, Xing Liu, Junhe Zhang, Xiaoyan Lu, Yongli Li, Meng Chen, Lingchao Chen,  and Chuanlu Jiang
26256-26268
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Opposite effects of GCN5 and PCAF knockdowns on the alternative mechanism of telomere maintenance

Opposite effects of GCN5 and PCAF knockdowns on the alternative mechanism of telomere maintenance

DOI: 10.18632/oncotarget.15447

Maya Jeitany, Dalal Bakhos-Douaihy, David C. Silvestre, Jose R. Pineda, Nicolas Ugolin, Angela Moussa, Laurent R. Gauthier, Didier Busso, Marie-Pierre Junier, Hervé Chneiweiss, Sylvie Chevillard, Chantal Desmaze,  and François D. Boussin
26269-26280
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circulating tumor DNA profiling by next generation sequencing reveals heterogeneity of crizotinib resistance mechanisms in a gastric cancer patient with MET amplification

Circulating tumor DNA profiling by next generation sequencing reveals heterogeneity of crizotinib resistance mechanisms in a gastric cancer patient with MET amplification

DOI: 10.18632/oncotarget.15457

Juan Du, Xue Wu, Xiaoling Tong, Xiaonan Wang, Jia Wei, Yang Yang, Zhili Chang, Yu Mao, Yang W Shao,  and Baorui Liu
26281-26287
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Promoter mutations and cellular distribution of telomerase in non-clear cell and clear cell hepatocellular carcinoma

Promoter mutations and cellular distribution of telomerase in non-clear cell and clear cell hepatocellular carcinoma

DOI: 10.18632/oncotarget.15458

Wan Huang, Weiping Zhou, Can Li, Yuan Yang, Yu-Kui Shang, Changsheng Chen, Jing Zhang, Rui Yao, Pei Wang, Wen Wen, Han-Qiang Liu, Ling Wang, Xia Li, Huijie Bian,  and Zhi-Nan Chen
26288-26297
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Krüppel-like factor 4 (KLF4) regulates the miR-183~96~182 cluster under physiologic and pathologic conditions

Krüppel-like factor 4 (KLF4) regulates the miR-183~96~182 cluster under physiologic and pathologic conditions

DOI: 10.18632/oncotarget.15459

Miguel F. Segura, Luz Jubierre, SiDe Li, Aroa Soriano, Lisa Koetz, Avital Gaziel-Sovran, Marc Masanas, Kevin Kleffman, John F. Dankert, Martin J Walsh,  and Eva Hernando
26298-26311
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Selenomethionine and methyl selenocysteine: multiple-dose pharmacokinetics in selenium-replete men

Selenomethionine and methyl selenocysteine: multiple-dose pharmacokinetics in selenium-replete men

DOI: 10.18632/oncotarget.15460

James R. Marshall, Raymond F. Burk, Rochelle Payne Ondracek, Kristina E. Hill, Marjorie Perloff, Warren Davis, Roberto Pili, Saby George,  and Raymond Bergan
26312-26322
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Tumor necrosis factor receptor 2/AKT and ERK signaling pathways contribute to the switch from fibroblasts to CAFs by progranulin in microenvironment of colorectal cancer

Tumor necrosis factor receptor 2/AKT and ERK signaling pathways contribute to the switch from fibroblasts to CAFs by progranulin in microenvironment of colorectal cancer

DOI: 10.18632/oncotarget.15461

Linlin Wang, Dong Yang, Jing Tian, Aiqin Gao, Yihang Shen, Xia Ren, Xia Li, Guosheng Jiang,  and Taotao Dong
26323-26333
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

microRNA-302c-3p inhibits renal cell carcinoma cell proliferation by targeting Grb2-associated binding 2 (Gab2)

microRNA-302c-3p inhibits renal cell carcinoma cell proliferation by targeting Grb2-associated binding 2 (Gab2)

DOI: 10.18632/oncotarget.15463

Dong-Hua Gu, Jia-Hui Mao, Xiao-Dong Pan, Hua Zhu, Xinfeng Chen, Bing Zheng,  and Yuxi Shan
26334-26343
Abstract  |   PDF  |  HTML  |  Order a Reprint

Poly (ADP-ribose) polymerase inhibitor, an effective radiosensitizer in lung and pancreatic cancers

Poly (ADP-ribose) polymerase inhibitor, an effective radiosensitizer in lung and pancreatic cancers

DOI: 10.18632/oncotarget.15464

Kedar Hastak, Steven Bhutra, Renate Parry,  and James M. Ford
26344-26355
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinicopathologic implications of immune classification by PD-L1 expression and CD8-positive tumor-infiltrating lymphocytes in stage II and III gastric cancer patients

Clinicopathologic implications of immune classification by PD-L1 expression and CD8-positive tumor-infiltrating lymphocytes in stage II and III gastric cancer patients

DOI: 10.18632/oncotarget.15465

Jiwon Koh, Chan-Young Ock, Jin Won Kim, Soo Kyung Nam, Yoonjin Kwak, Sumi Yun, Sang-Hoon Ahn, Do Joong Park, Hyung-Ho Kim, Woo Ho Kim,  and Hye Seung Lee
26356-26367
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The prognosis analysis of different metastasis pattern in patients with different breast cancer subtypes: a SEER based study

The prognosis analysis of different metastasis pattern in patients with different breast cancer subtypes: a SEER based study

DOI: 10.18632/oncotarget.14300

Haiyong Wang, Chenyue Zhang, Jingze Zhang, Li Kong, Hui Zhu,  and Jinming Yu
26368-26379
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Minichromosome maintenance protein 2 and 3 promote osteosarcoma progression via DHX9 and predict poor patient prognosis

Minichromosome maintenance protein 2 and 3 promote osteosarcoma progression via DHX9 and predict poor patient prognosis

DOI: 10.18632/oncotarget.15474

Dong-dong Cheng, Hui-zhen Zhang, Jun-qing Yuan, Shi-jie Li, Qing-cheng Yang,  and Cun-yi Fan
26380-26393
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of microRNAs associated with glioma diagnosis and prognosis

Identification of microRNAs associated with glioma diagnosis and prognosis

DOI: 10.18632/oncotarget.14445

Xinyun Ye, Wenjin Wei, Zhengyu Zhang, Chunming He, Ruijin Yang, Jinshi Zhang, Zhiwu Wu, Qianliang Huang,  and Qiuhua Jiang
26394-26403
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Effect of marital status on the survival of patients with gallbladder cancer treated with surgical resection: a population-based study

Effect of marital status on the survival of patients with gallbladder cancer treated with surgical resection: a population-based study

DOI: 10.18632/oncotarget.15476

Dou-Sheng Bai, Ping Chen, Jian-Jun Qian, Sheng-Jie Jin,  and Guo-Qing Jiang
26404-26413
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Genomic mutation-driven metastatic breast cancer therapy: a single center experience

Genomic mutation-driven metastatic breast cancer therapy: a single center experience

DOI: 10.18632/oncotarget.14476

Yuan Yuan, Susan E. Yost, Yate-Ching Yuan, Nicola M. Solomon, Isa Mambetsariev, Sumanta Pal, Paul Frankel, Ravi Salgia, Susan L. Neuhausen,  and Joanne Mortimer
26414-26423
Abstract  |   PDF  |  HTML  |  Order a Reprint

microRNA-135b expression silences Ppm1e to provoke AMPK activation and inhibit osteoblastoma cell proliferation

microRNA-135b expression silences Ppm1e to provoke AMPK activation and inhibit osteoblastoma cell proliferation

DOI: 10.18632/oncotarget.15477

Zheng-Wei Li, Yun-Rong Zhu, Xiao-Zhong Zhou, Bao-Biao Zhuo,  and Xiao-Dong Wang
26424-26433
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RAB10 overexpression promotes tumor growth and indicates poor prognosis of hepatocellular carcinoma

RAB10 overexpression promotes tumor growth and indicates poor prognosis of hepatocellular carcinoma

DOI: 10.18632/oncotarget.15507

Wei Wang, Wei-Dong Jia, Bing Hu,  and Yue-Yin Pan
26434-26447
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic role of metformin intake in diabetic patients with colorectal cancer: An updated qualitative evidence of cohort studies

Prognostic role of metformin intake in diabetic patients with colorectal cancer: An updated qualitative evidence of cohort studies

DOI: 10.18632/oncotarget.14688

Lili Du, Mingli Wang, Yingying Kang, Bo Li, Min Guo, Zhifeng Cheng,  and Changlong Bi
26448-26459
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Trichosanthin increases Granzyme B penetration into tumor cells by upregulation of CI-MPR on the cell surface

Trichosanthin increases Granzyme B penetration into tumor cells by upregulation of CI-MPR on the cell surface

DOI: 10.18632/oncotarget.15518

Chunman Li, Meiqi Zeng, Huju Chi, Jing Shen, Tzi-Bun Ng, Guangyi Jin, Desheng Lu, Xinmin Fan, Bilian Xiong, Zhangang Xiao,  and Ou Sha
26460-26470
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Histamine therapeutic efficacy in metastatic melanoma: Role of histamine H4 receptor agonists and opportunity for combination with radiation

Histamine therapeutic efficacy in metastatic melanoma: Role of histamine H4 receptor agonists and opportunity for combination with radiation

DOI: 10.18632/oncotarget.15594

Noelia A. Massari, Melisa B. Nicoud, Lorena Sambuco, Graciela P. Cricco, Diego J. Martinel Lamas, María V. Herrero Ducloux, Horacio Blanco, Elena S. Rivera,  and Vanina A. Medina
26471-26491
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression and functional regulation of stemness gene Lgr5 in esophageal squamous cell carcinoma

Expression and functional regulation of stemness gene Lgr5 in esophageal squamous cell carcinoma

DOI: 10.18632/oncotarget.15624

Zhuan Lv, Jane J. Yu, Wei-Jie Zhang, Li Xiong, Feng Wang, Li-Feng Li, Xue-Liang Zhou, Xin-Ya Gao, Xian-Fei Ding, Li Han, Ya-Fei Cai, Wang Ma,  and Liu-Xing Wang
26492-26504
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Autoimmune hematological diseases following haploidentical donor hematopoietic stem cell Transplant compared with matched sibling and unrelated donor

Autoimmune hematological diseases following haploidentical donor hematopoietic stem cell Transplant compared with matched sibling and unrelated donor

DOI: 10.18632/oncotarget.15710

Weiran Lv, Zhiping Fan, Fen Huang, Na Xu, Li Xuan, Guopan Yu, Qianli Jiang, Hongsheng Zhou, Ren Lin, Xin Zhang, Jing Sun,  and Qifa Liu
26505-26514
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The cell polarity protein Scrib functions as a tumor suppressor in liver cancer

The cell polarity protein Scrib functions as a tumor suppressor in liver cancer

DOI: 10.18632/oncotarget.15713

Shweta Kapil, Bal Krishan Sharma, Mallikarjun Patil, Sawsan Elattar, Jinling Yuan, Steven X. Hou, Ravindra Kolhe,  and Ande Satyanarayana
26515-26531
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Sodium butyrate improves porcine host defense peptide expression and relieves the inflammatory response upon toll-like receptor 2 activation and histone deacetylase inhibition in porcine kidney cells

Sodium butyrate improves porcine host defense peptide expression and relieves the inflammatory response upon toll-like receptor 2 activation and histone deacetylase inhibition in porcine kidney cells

DOI: 10.18632/oncotarget.15714

Xiujing Dou, Junlan Han, Wentao Song, Na Dong, Xinyao Xu, Wei Zhang,  and Anshan Shan
26532-26551
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Anti-MDA5 antibody as a potential diagnostic and prognostic biomarker in patients with dermatomyositis

Anti-MDA5 antibody as a potential diagnostic and prognostic biomarker in patients with dermatomyositis

DOI: 10.18632/oncotarget.15716

Liubing Li, Qian Wang, Funing Yang, Chanyuan Wu, Si Chen, Xiaoting Wen, Chenxi Liu,  and Yongzhe Li
26552-26564
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Laparoscopic versus open radical cystectomy for patients with bladder cancer over 75-year-old: a prospective randomized controlled trial

Laparoscopic versus open radical cystectomy for patients with bladder cancer over 75-year-old: a prospective randomized controlled trial

DOI: 10.18632/oncotarget.15717

Chen Yong, Chen Daihui,  and Zhou Bo
26565-26572
Abstract  |   PDF  |  HTML  |  Order a Reprint

Systematic identification and comparison of expressed profiles of lncRNAs and circRNAs with associated co-expression and ceRNA networks in mouse germline stem cells

Systematic identification and comparison of expressed profiles of lncRNAs and circRNAs with associated co-expression and ceRNA networks in mouse germline stem cells

DOI: 10.18632/oncotarget.15719

Xiaoyong Li, Junping Ao,  and Ji Wu
26573-26590
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genome-wide analysis of long noncoding RNA and mRNA co-expression profile in intrahepatic cholangiocarcinoma tissue by RNA sequencing

Genome-wide analysis of long noncoding RNA and mRNA co-expression profile in intrahepatic cholangiocarcinoma tissue by RNA sequencing

DOI: 10.18632/oncotarget.15721

Wenhui Yang, Yuan Li, Xia Song, Jun Xu,  and Jun Xie
26591-26599
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epigenetically altered miR-1247 functions as a tumor suppressor in pancreatic cancer

Epigenetically altered miR-1247 functions as a tumor suppressor in pancreatic cancer

DOI: 10.18632/oncotarget.15722

Joo Mi Yi, Eun-Jin Kang, Hyun-Mi Kwon, Jin-Han Bae, Keunsoo Kang, Nita Ahuja,  and Kwangmo Yang
26600-26612
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Synergistic killing of FLT3ITD-positive AML cells by combined inhibition of tyrosine-kinase activity and N-glycosylation

Synergistic killing of FLT3ITD-positive AML cells by combined inhibition of tyrosine-kinase activity and N-glycosylation

DOI: 10.18632/oncotarget.15772

Dimitrios Tsitsipatis, Ashok Kumar Jayavelu, Jörg P. Müller, Reinhard Bauer, Dirk Schmidt-Arras, Siavosh Mahboobi, Tina M. Schnöder, Florian Heidel,  and Frank D. Böhmer
26613-26624
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Value of circulating cell-free DNA analysis as a diagnostic tool for breast cancer: a meta-analysis

Value of circulating cell-free DNA analysis as a diagnostic tool for breast cancer: a meta-analysis

DOI: 10.18632/oncotarget.15775

Ziqiang Lin, James Neiswender, Bin Fang, Xuelei Ma, Jing Zhang,  and Xiuying Hu
26625-26636
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CBX7 is a glioma prognostic marker and induces G1/S arrest via the silencing of CCNE1

CBX7 is a glioma prognostic marker and induces G1/S arrest via the silencing of CCNE1

DOI: 10.18632/oncotarget.15789

Tianfu Yu, Youzhi Wu, Qi Hu, Junxia Zhang, Er Nie, Weining Wu, Xiefeng Wang, Yingyi Wang,  and Ning Liu
26637-26647
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of epidermal growth factor receptor attenuates LPS-induced inflammation and acute lung injury in rats

Inhibition of epidermal growth factor receptor attenuates LPS-induced inflammation and acute lung injury in rats

DOI: 10.18632/oncotarget.15790

Xiaoou Shan, Yali Zhang, Hongjin Chen, Lili Dong, Beibei Wu, Tingting Xu, Jie Hu, Zhiguo Liu, Wei Wang, Liqin Wu, Zhiguo Feng,  and Guang Liang
26648-26661
Abstract  |   PDF  |  HTML  |  Order a Reprint

CCDC106 promotes non-small cell lung cancer cell proliferation

CCDC106 promotes non-small cell lung cancer cell proliferation

DOI: 10.18632/oncotarget.15792

Xiupeng Zhang, Qin Zheng, Chen Wang, Haijing Zhou, Guiyang Jiang, Yuan Miao, Yong Zhang, Yang Liu, Qingchang Li, Xueshan Qiu,  and Enhua Wang
26662-26670
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Postoperative adjuvant TACE for patients of hepatocellular carcinoma in AJCC stage I: friend or foe? a propensity score analysis

Postoperative adjuvant TACE for patients of hepatocellular carcinoma in AJCC stage I: friend or foe? a propensity score analysis

DOI: 10.18632/oncotarget.15793

Yifan Tong, Zheyong Li, Yuelong Liang, Hong Yu, Xiao Liang, Hui Liu,  and Xiujun Cai
26671-26678
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Role of CD152 genetic polymorphisms in the susceptibility to breast cancer

Role of CD152 genetic polymorphisms in the susceptibility to breast cancer

DOI: 10.18632/oncotarget.15794

Hai Chen, Xiaodong Qi, Xue Bai, Ping Qiu,  and Bin Chen
26679-26686
Abstract  |   PDF  |  HTML  |  Order a Reprint

The vitamin D receptor is involved in the regulation of human breast cancer cell growth via a ligand-independent function in cytoplasm

The vitamin D receptor is involved in the regulation of human breast cancer cell growth via a ligand-independent function in cytoplasm

DOI: 10.18632/oncotarget.15803

Trupti Trivedi, Yu Zheng, Pierrick G.J. Fournier, Sreemala Murthy, Sutha John, Suzanne Schillo, Colin R. Dunstan, Khalid S. Mohammad, Hong Zhou, Markus J. Seibel,  and Theresa A. Guise
26687-26701
Abstract  |   PDF  |  HTML  |  Order a Reprint

Inactivation of p38 MAPK contributes to stem cell-like properties of non-small cell lung cancer

Inactivation of p38 MAPK contributes to stem cell-like properties of non-small cell lung cancer

DOI: 10.18632/oncotarget.15804

Yan Fang, Juan Wang, Guanwen Wang, Chen Zhou, Peng Wang, Shuangtao Zhao, Shaorong Zhao, Shan Huang, Weijun Su, Pengling Jiang, Antao Chang, Rong Xiang,  and Peiqing Sun
26702-26717
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TRIP13 impairs mitotic checkpoint surveillance and is associated with poor prognosis in multiple myeloma

TRIP13 impairs mitotic checkpoint surveillance and is associated with poor prognosis in multiple myeloma

DOI: 10.18632/oncotarget.14957

Yi Tao, Guang Yang, Hongxing Yang, Dongliang Song, Liangning Hu, Bingqian Xie, Houcai Wang, Lu Gao, Minjie Gao, Hongwei Xu, Zhijian Xu, Xiaosong Wu, Yiwen Zhang, Weiliang Zhu, Fenghuang Zhan,  and Jumei Shi
26718-26731
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

POLE and POLD1 screening in 155 patients with multiple polyps and early-onset colorectal cancer

POLE and POLD1 screening in 155 patients with multiple polyps and early-onset colorectal cancer

DOI: 10.18632/oncotarget.15810

Clara Esteban-Jurado, David Giménez-Zaragoza, Jenifer Muñoz, Sebastià Franch-Expósito, Miriam Álvarez-Barona, Teresa Ocaña, Miriam Cuatrecasas, Sabela Carballal, María López-Cerón, Maria Marti-Solano, Marcos Díaz-Gay, Tom van Wezel, Antoni Castells, Luis Bujanda, Judith Balmaña, Victoria Gonzalo, Gemma Llort, Clara Ruiz-Ponte, Joaquín Cubiella, Francesc Balaguer, Rosa Aligué,  and Sergi Castellví-Bel
26732-26743
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comprehensive immunohistochemical study of mesothelin (MSLN) using different monoclonal antibodies 5B2 and MN-1 in 1562 tumors with evaluation of its prognostic value in malignant pleural mesothelioma

Comprehensive immunohistochemical study of mesothelin (MSLN) using different monoclonal antibodies 5B2 and MN-1 in 1562 tumors with evaluation of its prognostic value in malignant pleural mesothelioma

DOI: 10.18632/oncotarget.15814

Shingo Inaguma, Zengfeng Wang, Jerzy Lasota, Masanori Onda, Piotr Czapiewski, Renata Langfort, Janusz Rys, Joanna Szpor, Piotr Waloszczyk, Krzysztof Okoń, Wojciech Biernat, Hiroshi Ikeda, David S. Schrump, Raffit Hassan, Ira Pastan,  and Markku Miettinen
26744-26754
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical relevance of the transcriptional signature regulated by CDC42 in colorectal cancer

Clinical relevance of the transcriptional signature regulated by CDC42 in colorectal cancer

DOI: 10.18632/oncotarget.15815

Fatima Valdés-Mora, Warwick J. Locke, Eva Bandrés, David Gallego-Ortega, Paloma Cejas, Miguel Angel García-Cabezas, Yolanda Colino-Sanguino, Jaime Feliú, Teresa Gómez del Pulgar,  and Juan Carlos Lacal
26755-26770
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumor regression is mediated via the induction of HER263-71- specific CD8+ CTL activity in a 4T1.2/HER2 tumor model: no involvement of CD80 in tumor control

Tumor regression is mediated via the induction of HER263-71- specific CD8+ CTL activity in a 4T1.2/HER2 tumor model: no involvement of CD80 in tumor control

DOI: 10.18632/oncotarget.15816

Sayyed Nilofar Danishmalik, Si-Hyeong Lee,  and Jeong-Im Sin
26771-26788
Abstract  |   PDF  |  HTML  |  Order a Reprint

The prognostic role of immune checkpoint markers programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) in a large, multicenter prostate cancer cohort

The prognostic role of immune checkpoint markers programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) in a large, multicenter prostate cancer cohort

DOI: 10.18632/oncotarget.15817

Nora Ness, Sigve Andersen, Mehrdad Rakaee Khanehkenari, Cecilie V. Nordbakken, Andrej Valkov, Erna-Elise Paulsen, Yngve Nordby, Roy M. Bremnes, Tom Donnem, Lill-Tove Busund,  and Elin Richardsen
26789-26801
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SET oncoprotein accumulation regulates transcription through DNA demethylation and histone hypoacetylation

SET oncoprotein accumulation regulates transcription through DNA demethylation and histone hypoacetylation

DOI: 10.18632/oncotarget.15818

Luciana O. Almeida, Marinaldo P.C. Neto, Lucas O. Sousa, Maryna A. Tannous, Carlos Curti,  and Andreia M. Leopoldino
26802-26818
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PPARγ activation by troglitazone enhances human lung cancer cells to TRAIL-induced apoptosis via autophagy flux

PPARγ activation by troglitazone enhances human lung cancer cells to TRAIL-induced apoptosis via autophagy flux

DOI: 10.18632/oncotarget.15819

Uddin MD. Nazim, Ji-Hong Moon, You-Jin Lee, Jae-Won Seol,  and Sang-Youel Park
26819-26831
Abstract  |   PDF  |  HTML  |  Order a Reprint

Functional characterisation of a novel ovarian cancer cell line, NUOC-1

Functional characterisation of a novel ovarian cancer cell line, NUOC-1

DOI: 10.18632/oncotarget.15821

Aiste McCormick, Eleanor Earp, Katherine Elliot, Gavin Cuthbert, Rachel O'Donnell, Brian T. Wilson, Ruth Sutton, Charlotte Leeson, Huw D. Thomas, Helen Blair, Sarah Fordham, John Lunec, James Allan,  and Richard J. Edmondson
26832-26844
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PD-L1 expression and its relationship with oncogenic drivers in non-small cell lung cancer (NSCLC)

PD-L1 expression and its relationship with oncogenic drivers in non-small cell lung cancer (NSCLC)

DOI: 10.18632/oncotarget.15839

Liyan Jiang, Xinying Su, Tianwei Zhang, Xiaolu Yin, Meizhuo Zhang, Haihua Fu, Hulin Han, Yun Sun, Lili Dong, Jialin Qian, Yanhua Xu, Xuan Fu, Paul R. Gavine, Yanbin Zhou, Kun Tian, Jiaqi Huang, Dong Shen, Haiyi Jiang, Yihong Yao, Baohui Han,  and Yi Gu
26845-26857
Abstract  |   PDF  |  HTML  |  Order a Reprint

Identification of microRNA 885-5p as a novel regulator of tumor metastasis by targeting CPEB2 in colorectal cancer

Identification of microRNA 885-5p as a novel regulator of tumor metastasis by targeting CPEB2 in colorectal cancer

DOI: 10.18632/oncotarget.15844

Colin Siu-Chi Lam, Lui Ng, Ariel Ka-Man Chow, Timothy Ming-Hun Wan, Simon Yau, Nathan Shiu-Man Cheng, Sunny Kit-Man Wong, Johnny Hon-Wai Man, Oswens Siu-Hung Lo, Dominic Chi-Chung Foo, Jensen Tung-Chung Poon, Roberta Wen-Chi Pang,  and Wai-Lun Law
26858-26870
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel oncolytic adenovirus based on simian adenovirus serotype 24

A novel oncolytic adenovirus based on simian adenovirus serotype 24

DOI: 10.18632/oncotarget.15845

Tao Cheng, Yufeng Song, Yan Zhang, Chao Zhang, Jieyun Yin, Yudan Chi,  and Dongming Zhou
26871-26885
Abstract  |   PDF  |  HTML  |  Order a Reprint

NCTD promotes Birinapant-mediated anticancer activity in breast cancer cells by downregulation of c-FLIP

NCTD promotes Birinapant-mediated anticancer activity in breast cancer cells by downregulation of c-FLIP

DOI: 10.18632/oncotarget.15848

Li Zhao, Guoshan Yang, Hao Bai, Minghui Zhang,  and Dongcheng Mou
26886-26895
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Fungal lectin MpL enables entry of protein drugs into cancer cells and their subcellular targeting

Fungal lectin MpL enables entry of protein drugs into cancer cells and their subcellular targeting

DOI: 10.18632/oncotarget.15849

Simon Žurga, Milica Perišić Nanut, Janko Kos,  and Jerica Sabotič
26896-26910
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-29a-deficiency does not modify the course of murine pancreatic acinar carcinoma

miR-29a-deficiency does not modify the course of murine pancreatic acinar carcinoma

DOI: 10.18632/oncotarget.15850

James Dooley, Vasiliki Lagou, Josselyn E. Garcia-Perez, Uwe Himmelreich,  and Adrian Liston
26911-26917
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TT genotype of rs2941484 in the human HNF4G gene is associated with hyperuricemia in Chinese Han men

TT genotype of rs2941484 in the human HNF4G gene is associated with hyperuricemia in Chinese Han men

DOI: 10.18632/oncotarget.15851

Bang-Dang Chen, Xiao-Cui Chen, Shuo Pan, Yi-Ning Yang, Chun-Hui He, Fen Liu, Xiang Ma, Min-Tao Gai,  and Yi-Tong Ma
26918-26926
Abstract  |   PDF  |  HTML  |  Order a Reprint

Triptolide suppresses the in vitro and in vivo growth of lung cancer cells by targeting hyaluronan-CD44/RHAMM signaling

Triptolide suppresses the in vitro and in vivo growth of lung cancer cells by targeting hyaluronan-CD44/RHAMM signaling

DOI: 10.18632/oncotarget.15879

Jung Min Song, Kalkidan Molla, Arunkumar Anandharaj, Ingrid Cornax, M. Gerard O`Sullivan, Ameya R. Kirtane, Jayanth Panyam,  and Fekadu Kassie
26927-26940
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Astragalin-induced cell death is caspase-dependent and enhances the susceptibility of lung cancer cells to tumor necrosis factor by inhibiting the NF-кB pathway

Astragalin-induced cell death is caspase-dependent and enhances the susceptibility of lung cancer cells to tumor necrosis factor by inhibiting the NF-кB pathway

DOI: 10.18632/oncotarget.15264

Minghui Chen, Fangfang Cai, Daolong Zha, Xueshi Wang, Wenjing Zhang, Yan He, Qilai Huang, Hongqin Zhuang,  and Zi-Chun Hua
26941-26958
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The relative efficacy and safety of targeted agents used in combination with chemotherapy in treating patients with untreated advanced gastric cancer: a network meta-analysis

The relative efficacy and safety of targeted agents used in combination with chemotherapy in treating patients with untreated advanced gastric cancer: a network meta-analysis

DOI: 10.18632/oncotarget.15923

Shuping Xie, Huixiang Zhang, Xueyan Wang, Quanxing Ge,  and Junhong Hu
26959-26968
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

hTERT promotes gastric intestinal metaplasia by upregulating CDX2 via NF-κB signaling pathway

hTERT promotes gastric intestinal metaplasia by upregulating CDX2 via NF-κB signaling pathway

DOI: 10.18632/oncotarget.15926

Bai-Jun Chen, Shuo Zeng, Rui Xie, Chang-Jiang Hu, Su-Ming Wang, Yu-Yun Wu, Yu-Feng Xiao,  and Shi-Ming Yang
26969-26978
Abstract  |   PDF  |  HTML  |  Order a Reprint

Protein phosphatase 2A regulatory subunit B55α functions in mouse oocyte maturation and early embryonic development

Protein phosphatase 2A regulatory subunit B55α functions in mouse oocyte maturation and early embryonic development

DOI: 10.18632/oncotarget.15927

Shuang Liang, Jing Guo, Jeong-Woo Choi, Kyung-Tae Shin, Hai-Yang Wang, Yu-Jin Jo, Nam-Hyung Kim,  and Xiang-Shun Cui
26979-26991
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hispidin induces autophagic and necrotic death in SGC-7901 gastric cancer cells through lysosomal membrane permeabilization by inhibiting tubulin polymerization

Hispidin induces autophagic and necrotic death in SGC-7901 gastric cancer cells through lysosomal membrane permeabilization by inhibiting tubulin polymerization

DOI: 10.18632/oncotarget.15935

Long-Xian Lv, Zhen-Xing Zhou, Zhan Zhou, Li-Jiang Zhang, Ren Yan, Zhao Zhao, Li-Ya Yang, Xiao-Yuan Bian, Hui-Yong Jiang, Yu-Dong Li, Yi-Sheng Sun, Qin-Qin Xu, Gui-Li Hu, Wen-Jun Guan,  and Yong-Quan Li
26992-27006
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Network pharmacology-based and clinically relevant prediction of the active ingredients and potential targets of Chinese herbs in metastatic breast cancer patients

Network pharmacology-based and clinically relevant prediction of the active ingredients and potential targets of Chinese herbs in metastatic breast cancer patients

DOI: 10.18632/oncotarget.15351

Yu Mao, Jian Hao, Zi-qi Jin, Yang-yang Niu, Xue Yang, Dan Liu, Rui Cao,  and Xiong-zhi Wu
27007-27021
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Skip lateral lymph node metastasis leaping over the central neck compartment in papillary thyroid carcinoma

Skip lateral lymph node metastasis leaping over the central neck compartment in papillary thyroid carcinoma

DOI: 10.18632/oncotarget.15388

Jianyong Lei, Jinjing Zhong, Ke Jiang, Zhihui Li, Rixiang Gong,  and Jingqiang Zhu
27022-27033
Abstract  |   PDF  |  HTML  |  Order a Reprint

The extracellular matrix protein EMILIN1 silences the RAS-ERK pathway via α4β1 integrin and decreases tumor cell growth

The extracellular matrix protein EMILIN1 silences the RAS-ERK pathway via α4β1 integrin and decreases tumor cell growth

DOI: 10.18632/oncotarget.15067

Teresa Maria Elisa Modica, Orlando Maiorani, Giulio Sartori, Eliana Pivetta, Roberto Doliana, Alessandra Capuano, Alfonso Colombatti,  and Paola Spessotto
27034-27046
Abstract  |   PDF  |  HTML  |  Order a Reprint

Small RNA sequencing reveals metastasis-related microRNAs in lung adenocarcinoma

Small RNA sequencing reveals metastasis-related microRNAs in lung adenocarcinoma

DOI: 10.18632/oncotarget.15968

Iben Daugaard, Morten T. Venø, Yan Yan, Tina E. Kjeldsen, Philippe Lamy, Henrik Hager, Jørgen Kjems,  and Lise Lotte Hansen
27047-27061
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma

Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma

DOI: 10.18632/oncotarget.16003

Jon Bjoern, Rikke Lyngaa, Rikke Andersen, Lisbet Hölmich Rosenkrantz, Sine Reker Hadrup, Marco Donia,  and Inge Marie Svane
27062-27074
Abstract  |   PDF  |  HTML  |  Order a Reprint

Human a-L-fucosidase-1 attenuates the invasive properties of thyroid cancer

Human a-L-fucosidase-1 attenuates the invasive properties of thyroid cancer

DOI: 10.18632/oncotarget.15635

Giancarlo Vecchio, Alessia Parascandolo, Chiara Allocca, Clara Ugolini, Fulvio Basolo, Marco Moracci, Andrea Strazzulli, Beatrice Cobucci-Ponzano, Mikko O. Laukkanen, Maria Domenica Castellone,  and Nobuo Tsuchida
27075-27092
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Paeonol suppresses solar ultraviolet-induced skin inflammation by targeting T-LAK cell-originated protein kinase

Paeonol suppresses solar ultraviolet-induced skin inflammation by targeting T-LAK cell-originated protein kinase

DOI: 10.18632/oncotarget.15636

Peipei Xue, Yong Wang, Fanfan Zeng, Ruijuan Xiu, Jingwen Chen, Jinguang Guo, Ping Yuan, Lin Liu, Juanjuan Xiao, Hui Lu, Dan Wu, Huaxiong Pan, Mingmin Lu, Feng Zhu, Fei Shi,  and Qiuhong Duan
27093-27104
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Noncanonical Wnt signaling plays an important role in modulating canonical Wnt-regulated stemness, proliferation and terminal differentiation of hepatic progenitors

Noncanonical Wnt signaling plays an important role in modulating canonical Wnt-regulated stemness, proliferation and terminal differentiation of hepatic progenitors

DOI: 10.18632/oncotarget.15637

Jiaming Fan, Qiang Wei, Junyi Liao, Yulong Zou, Dongzhe Song, Dongmei Xiong, Chao Ma, Xue Hu, Xiangyang Qu, Liqun Chen, Li Li, Yichun Yu, Xinyi Yu, Zhicai Zhang, Chen Zhao, Zongyue Zeng, Ruyi Zhang, Shujuan Yan, Tingting Wu, Xingye Wu, Yi Shu, Jiayan Lei, Yasha Li, Wenwen Zhang, Rex C. Haydon, Hue H. Luu, Ailong Huang, Tong-Chuan He,  and Hua Tang
27105-27119
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gambogic acid suppresses cancer invasion and migration by inhibiting TGFβ1-induced epithelial-to-mesenchymal transition

Gambogic acid suppresses cancer invasion and migration by inhibiting TGFβ1-induced epithelial-to-mesenchymal transition

DOI: 10.18632/oncotarget.15449

Kai Zhao, Shuai Zhang, Xiuming Song, Yuyuan Yao, Yuxin Zhou, Qidong You, Qing-Long Guo,  and Na Lu
27120-27136
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic role of B7-H4 in patients with non-small cell lung cancer: A meta-analysis

Prognostic role of B7-H4 in patients with non-small cell lung cancer: A meta-analysis

DOI: 10.18632/oncotarget.15648

Zhibo Tan,  and Weixi Shen
27137-27144
Abstract  |   PDF  |  HTML  |  Order a Reprint

Experience with precision genomics and tumor board, indicates frequent target identification, but barriers to delivery

Experience with precision genomics and tumor board, indicates frequent target identification, but barriers to delivery

DOI: 10.18632/oncotarget.16057

Alan H. Bryce, Jan B. Egan, Mitesh J. Borad, A. Keith Stewart, Grzegorz S. Nowakowski, Asher Chanan-Khan, Mrinal M. Patnaik, Stephen M. Ansell, Michaela S. Banck, Steven I. Robinson, Aaron S. Mansfield, Eric W. Klee, Gavin R. Oliver, Jennifer B. McCormick, Norine E. Huneke, Colleen M. Tagtow, Robert B. Jenkins, Kandelaria M. Rumilla, Sarah E. Kerr, Jean-Pierre A. Kocher, Scott A. Beck, Martin E. Fernandez-Zapico, Gianrico Farrugia, Konstantinos N. Lazaridis,  and Robert R. McWilliams
27145-27154
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

EGFR mediates activation of RET in lung adenocarcinoma with neuroendocrine differentiation characterized by ASCL1 expression

EGFR mediates activation of RET in lung adenocarcinoma with neuroendocrine differentiation characterized by ASCL1 expression

DOI: 10.18632/oncotarget.15676

Kaustubh Bhinge, Lin Yang, Simone Terra, Aqsa Nasir, Prasuna Muppa, Marie Christine Aubry, Joanne Yi, Nafiseh Janaki, Irina V. Kovtun, Stephen J. Murphy, Geoffrey Halling, Hamed Rahi, Aaron Mansfield, Mariza de Andrade, Ping Yang, George Vasmatzis, Tobias Peikert,  and Farhad Kosari
27155-27165
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sphingosine-1-phosphate promotes ovarian cancer cell proliferation by disrupting Hippo signaling

Sphingosine-1-phosphate promotes ovarian cancer cell proliferation by disrupting Hippo signaling

DOI: 10.18632/oncotarget.15677

Qianlan Fan, Yuan Cheng, Hsun-Ming Chang, Masashi Deguchi, Aaron J. Hsueh,  and Peter C.K. Leung
27166-27176
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Simultaneous sentinel lymph node computed tomography and locoregional chemotherapy for lymph node metastasis in rabbit using an iodine-docetaxel emulsion

Simultaneous sentinel lymph node computed tomography and locoregional chemotherapy for lymph node metastasis in rabbit using an iodine-docetaxel emulsion

DOI: 10.18632/oncotarget.15679

Honsoul Kim, Eun-Ji Jang, Sang Kyum Kim, Woo Jin Hyung, Dong Kyu Choi, Soo-Jeong Lim,  and Joon Seok Lim
27177-27188
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The antitumor activity and preliminary modeling on the potential mechanism of action of human peroxiredoxin-5

The antitumor activity and preliminary modeling on the potential mechanism of action of human peroxiredoxin-5

DOI: 10.18632/oncotarget.16089

Juanjuan Liu, Xiaozhou Feng, Yuanyuan Jin, Zhengyang Sun, Haoyi Meng, Zhifei Zhang, Laixing Hu,  and Zhaoyong Yang
27189-27198
Abstract  |   PDF  |  HTML  |  Order a Reprint

Model-based unsupervised learning informs metformin-induced cell-migration inhibition through an AMPK-independent mechanism in breast cancer

Model-based unsupervised learning informs metformin-induced cell-migration inhibition through an AMPK-independent mechanism in breast cancer

DOI: 10.18632/oncotarget.16109

Arjun P. Athreya, Krishna R. Kalari, Junmei Cairns, Alan J. Gaglio, Quin F. Wills, Nifang Niu, Richard Weinshilboum, Ravishankar K. Iyer,  and Liewei Wang
27199-27215
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Systematic analysis of gene expression alterations and clinical outcomes of adenylate cyclase-associated protein in cancer

Systematic analysis of gene expression alterations and clinical outcomes of adenylate cyclase-associated protein in cancer

DOI: 10.18632/oncotarget.16111

Shuanshuan Xie, Changxing Shen, Min Tan, Ming Li, Xiaolian Song,  and Changhui Wang
27216-27239
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of lysophosphatidic acid receptor ameliorates Sjögren’s syndrome in NOD mice

Inhibition of lysophosphatidic acid receptor ameliorates Sjögren’s syndrome in NOD mice

DOI: 10.18632/oncotarget.15916

Eunhye Park, Donghee Kim, Song Mi Lee,  and Hee-Sook Jun
27240-27251
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combination therapy with dendritic cells and lenalidomide is an effective approach to enhance antitumor immunity in a mouse colon cancer model

Combination therapy with dendritic cells and lenalidomide is an effective approach to enhance antitumor immunity in a mouse colon cancer model

DOI: 10.18632/oncotarget.15917

Manh-Cuong Vo, Thanh-Nhan Nguyen-Pham, Hyun-Ju Lee, Thangaraj Jaya Lakshmi, Seoyun Yang, Sung-Hoon Jung, Hyeoung-Joon Kim,  and Je-Jung Lee
27252-27262
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SHP2 is induced by the HBx-NF-κB pathway and contributes to fibrosis during human early hepatocellular carcinoma development

SHP2 is induced by the HBx-NF-κB pathway and contributes to fibrosis during human early hepatocellular carcinoma development

DOI: 10.18632/oncotarget.15930

Hyo Jeong Kang, Dal-Hee Chung, Chang Ohk Sung, Su Hyun Yoo, Eunsil Yu, Nayoung Kim, Su-hye Lee, Ji-young Song, Chong Jai Kim,  and Jene Choi
27263-27276
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gene-based comparative analysis of tools for estimating copy number alterations using whole-exome sequencing data

Gene-based comparative analysis of tools for estimating copy number alterations using whole-exome sequencing data

DOI: 10.18632/oncotarget.15932

Hyung-Yong Kim, Jin-Woo Choi, Jeong-Yeon Lee,  and Gu Kong
27277-27285
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A bispecific enediyne-energized fusion protein targeting both epidermal growth factor receptor and insulin-like growth factor 1 receptor showing enhanced antitumor efficacy against non-small cell lung cancer

A bispecific enediyne-energized fusion protein targeting both epidermal growth factor receptor and insulin-like growth factor 1 receptor showing enhanced antitumor efficacy against non-small cell lung cancer

DOI: 10.18632/oncotarget.15933

Xiao-fang Guo, Xiao-fei Zhu, Hai-ying Cao, Gen-shen Zhong, Liang Li, Bao-guo Deng, Ping Chen, Pei-zhen Wang, Qing-fang Miao,  and Yong-su Zhen
27286-27299
Abstract  |    |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The β-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner

The β-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner

DOI: 10.18632/oncotarget.15934

Maria Wiese, Neele Walther, Christopher Diederichs, Fabian Schill, Sebastian Monecke, Gabriela Salinas, Dominik Sturm, Stefan M. Pfister, Ralf Dressel, Steven A. Johnsen,  and Christof M. Kramm
27300-27313
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HMGB1 promotes differentiation syndrome by inducing hyperinflammation via MEK/ERK signaling in acute promyelocytic leukemia cells

HMGB1 promotes differentiation syndrome by inducing hyperinflammation via MEK/ERK signaling in acute promyelocytic leukemia cells

DOI: 10.18632/oncotarget.15432

Lanlan Tang, Wenwen Chai, Fanghua Ye, Yan Yu, Lizhi Cao, Minghua Yang, Min Xie,  and Liangchun Yang
27314-27327
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epstein-Barr virus (EBV)-encoded small RNAs (EBERs) associated with poor prognosis of head and neck carcinomas

Epstein-Barr virus (EBV)-encoded small RNAs (EBERs) associated with poor prognosis of head and neck carcinomas

DOI: 10.18632/oncotarget.16033

Turunen Aaro, Rautava Jaana, Grénman Reidar, Syrjänen Kari,  and Syrjänen Stina
27328-27338
Abstract  |    |  PDF  |  HTML  |  Order a Reprint

Improvement of dexamethasone sensitivity by chelation of intracellular Ca2+ in pediatric acute lymphoblastic leukemia cells through the prosurvival kinase ERK1/2 deactivation

Improvement of dexamethasone sensitivity by chelation of intracellular Ca2+ in pediatric acute lymphoblastic leukemia cells through the prosurvival kinase ERK1/2 deactivation

DOI: 10.18632/oncotarget.16039

Souleymane Abdoul-Azize, Isabelle Dubus,  and Jean-Pierre Vannier
27339-27352
Abstract  |   PDF  |  HTML  |  Order a Reprint

Essential role of endogenous prolactin and CDK7 in estrogen-induced upregulation of the prolactin receptor in breast cancer cells

Essential role of endogenous prolactin and CDK7 in estrogen-induced upregulation of the prolactin receptor in breast cancer cells

DOI: 10.18632/oncotarget.16040

Raghuveer Kavarthapu,  and Maria L. Dufau
27353-27363
Abstract  |   PDF  |  HTML  |  Order a Reprint

Identification of Ras suppressor-1 (RSU-1) as a potential breast cancer metastasis biomarker using a three-dimensional in vitro approach

Identification of Ras suppressor-1 (RSU-1) as a potential breast cancer metastasis biomarker using a three-dimensional in vitro approach

DOI: 10.18632/oncotarget.16062

Vasiliki Gkretsi, Andreas Stylianou, Maria Louca,  and Triantafyllos Stylianopoulos
27364-27379
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer

Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer

DOI: 10.18632/oncotarget.16068

Noa Rabinowicz, Lingegowda S. Mangala, Kevin R. Brown, Cintia Checa-Rodriguez, Asher Castiel, Oren Moskovich, Giulia Zarfati, Luba Trakhtenbrot, Adva Levy-Barda, Dahai Jiang, Cristian Rodriguez-Aguayo, Sunila Pradeep, Yael van Praag, Gabriel Lopez-Berestein, Ahuvit David, Ilya Novikov, Pablo Huertas, Robert Rottapel, Anil K. Sood,  and Shai Izraeli
27380-27392
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of serum miR-139-3p as a non-invasive biomarker for colorectal cancer

Identification of serum miR-139-3p as a non-invasive biomarker for colorectal cancer

DOI: 10.18632/oncotarget.16171

Lui Ng, Timothy Ming-Hun Wan, Johnny Hon-Wai Man, Ariel Ka-Man Chow, Deepak Iyer, Guanghua Chen, Thomas Chung-Cheung Yau, Oswens Siu-Hung Lo, Dominic Chi-Chung Foo, Jensen Tung-Chung Poon, Wai-Keung Leung, Roberta Wen-Chi Pang,  and Wai-Lun Law
27393-27400
Abstract  |   PDF  |  HTML  |  Order a Reprint

Impact of statins therapy on morphological changes in lipid-rich plaques stratified by 10-Year framingham risk score: A serial optical coherence tomography study

Impact of statins therapy on morphological changes in lipid-rich plaques stratified by 10-Year framingham risk score: A serial optical coherence tomography study

DOI: 10.18632/oncotarget.16172

Yinchun Zhu, Lin Lin, Chao Wang, Haibo Jia, Sining Hu, Lulu Li, Xiling Zhang, Gonghui Zheng, Yan Wang, Rong Sun, Abigail Afolabi, Irina Mustafina, Jingbo Hou, Shaosong Zhang,  and Bo Yu
27401-27411
Abstract  |   PDF  |  HTML  |  Order a Reprint

GLI1-mediated regulation of side population is responsible for drug resistance in gastric cancer

GLI1-mediated regulation of side population is responsible for drug resistance in gastric cancer

DOI: 10.18632/oncotarget.16174

Beiqin Yu, Dongsheng Gu, Xiaoli Zhang, Jianfang Li, Bingya Liu,  and Jingwu Xie
27412-27427
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Development of a radiosensitivity gene signature for patients with soft tissue sarcoma

Development of a radiosensitivity gene signature for patients with soft tissue sarcoma

DOI: 10.18632/oncotarget.16194

Zaixiang Tang, Qinghua Zeng, Yan Li, Xinyan Zhang, Jinlu Ma, Mark J. Suto, Bo Xu,  and Nengjun Yi
27428-27439
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Decreased ATF4 expression as a mechanism of acquired resistance to long-term amino acid limitation in cancer cells

Decreased ATF4 expression as a mechanism of acquired resistance to long-term amino acid limitation in cancer cells

DOI: 10.18632/oncotarget.15828

Florent Mesclon, Sarah Lambert-Langlais, Valérie Carraro, Laurent Parry, Isabelle Hainault, Céline Jousse, Anne-Catherine Maurin, Alain Bruhat, Pierre Fafournoux,  and Julien Averous
27440-27453
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Multi-factorial modulation of colorectal carcinoma cells motility – partial coordination by the tetraspanin Co-029/tspan8

Multi-factorial modulation of colorectal carcinoma cells motility – partial coordination by the tetraspanin Co-029/tspan8

DOI: 10.18632/oncotarget.16247

Yingying Zhu, Naouel Ailane, Monica Sala-Valdés, Farhad Haghighi-Rad, Martine Billard, Viet Nguyen, Raphael Saffroy, Antoinette Lemoine, Eric Rubinstein, Claude Boucheix,  and Céline Greco
27454-27470
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Luteolin inhibits cell proliferation and induces cell apoptosis via down-regulation of mitochondrial membrane potential in esophageal carcinoma cells EC1 and KYSE450

Luteolin inhibits cell proliferation and induces cell apoptosis via down-regulation of mitochondrial membrane potential in esophageal carcinoma cells EC1 and KYSE450

DOI: 10.18632/oncotarget.15832

Ping Chen, Jing-Yang Zhang, Bei-Bei Sha, Yan-Er Ma, Tao Hu, Yang-Cheng Ma, Hao Sun, Jian-Xiang Shi, Zi-Ming Dong,  and Pei Li
27471-27480
Abstract  |   PDF  |  HTML  |  Order a Reprint

Single nucleotide polymorphisms in CIDEC gene are associated with metabolic syndrome components risks and antihypertensive drug efficacy

Single nucleotide polymorphisms in CIDEC gene are associated with metabolic syndrome components risks and antihypertensive drug efficacy

DOI: 10.18632/oncotarget.16078

Hui Wang, Yun Ti, Jin-Bo Zhang, Jie Peng, Hui-Min Zhou, Ming Zhong, Yan-Qiu Xing, Yun Zhang, Wei Zhang,  and Zhi-Hao Wang
27481-27488
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Preoperative pulmonary function correlates with systemic inflammatory response and prognosis in patients with non-small cell lung cancer: results of a single-institution retrospective study

Preoperative pulmonary function correlates with systemic inflammatory response and prognosis in patients with non-small cell lung cancer: results of a single-institution retrospective study

DOI: 10.18632/oncotarget.14225

Yongyin Gao, Hongdian Zhang, Yue Li, Dandan Wang, Yinlu Ma,  and Qing Chen
27489-27501
Abstract  |    |  PDF  |  HTML  |  Order a Reprint

Randomized clinical trial comparing the effects of sevoflurane and propofol on carbon dioxide embolism during pneumoperitoneum in laparoscopic hepatectomy

Randomized clinical trial comparing the effects of sevoflurane and propofol on carbon dioxide embolism during pneumoperitoneum in laparoscopic hepatectomy

DOI: 10.18632/oncotarget.15492

Yu Hong, Yu Xin, Fei Yue, He Qi,  and Cai Jun
27502-27509
Abstract  |   PDF  |  HTML  |  Order a Reprint

Early outcome of early-goal directed therapy for patients with sepsis or septic shock: a systematic review and meta-analysis of randomized controlled trials

Early outcome of early-goal directed therapy for patients with sepsis or septic shock: a systematic review and meta-analysis of randomized controlled trials

DOI: 10.18632/oncotarget.15550

Xiaofan Chen, Weifeng Zhu, Jing Tan, Heyun Nie, Liangming Liu, Dongmei Yan, Xu Zhou,  and Xin Sun
27510-27519
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ultrasonographic characteristics of medullary thyroid carcinoma: a comparison with papillary thyroid carcinoma

Ultrasonographic characteristics of medullary thyroid carcinoma: a comparison with papillary thyroid carcinoma

DOI: 10.18632/oncotarget.15897

Mei-juan Liu, Zhong-feng Liu, Yuan-yuan Hou, Yan-Ming Men, Yu-Xi Zhang, Ling-Yun Gao,  and Hao Liu
27520-27528
Abstract  |   PDF  |  HTML  |  Order a Reprint

Clinical study of the time of repeated computed tomography and replanning for patients with nasopharyngeal carcinoma

Clinical study of the time of repeated computed tomography and replanning for patients with nasopharyngeal carcinoma

DOI: 10.18632/oncotarget.16770

Xiujuan Gai, Yumei Wei, Hengmin Tao, Jian Zhu,  and Baosheng Li
27529-27540
Abstract  |   PDF  |  HTML  |  Order a Reprint

Reviews

Statins in conditions other than hypocholesterolemic effects for chronic subdural hematoma therapy, old drug, new tricks?

Statins in conditions other than hypocholesterolemic effects for chronic subdural hematoma therapy, old drug, new tricks?

DOI: 10.18632/oncotarget.15092

Hai Zou, Xing-Xing Zhu, Ya-Hui Ding, Guo-Bing Zhang, Yu Geng,  and Dong-Sheng Huang
27541-27546
Abstract  |   PDF  |  HTML  |  Order a Reprint

Dysregulation of miRNAs in bladder cancer: altered expression with aberrant biogenesis procedure

Dysregulation of miRNAs in bladder cancer: altered expression with aberrant biogenesis procedure

DOI: 10.18632/oncotarget.15173

Fan Dong, Tianyuan Xu, Yifan Shen, Shan Zhong, Shanwen Chen, Qiang Ding,  and Zhoujun Shen
27547-27568
Abstract  |   PDF  |  HTML  |  Order a Reprint

Tat is a multifunctional viral protein that modulates cellular gene expression and functions

Tat is a multifunctional viral protein that modulates cellular gene expression and functions

DOI: 10.18632/oncotarget.15174

Evan Clark, Brenda Nava,  and Massimo Caputi
27569-27581
Abstract  |   PDF  |  HTML  |  Order a Reprint

Long non-coding RNA in glioma: signaling pathways

Long non-coding RNA in glioma: signaling pathways

DOI: 10.18632/oncotarget.15175

Jia Shi, Bo Dong, Jiachao Cao, Yumin Mao, Wei Guan, Ya Peng,  and Suinuan Wang
27582-27592
Abstract  |   PDF  |  HTML  |  Order a Reprint

Interacting partners of FEN1 and its role in the development of anticancer therapeutics

Interacting partners of FEN1 and its role in the development of anticancer therapeutics

DOI: 10.18632/oncotarget.15176

Chandrasekhar Kathera, Jing Zhang, Avilala Janardhan, Hongfang Sun, Wajid Ali, Xiaolong Zhou, Lingfeng He,  and Zhigang Guo
27593-27602
Abstract  |   PDF  |  HTML  |  Order a Reprint

The association between nuclear receptors and ocular diseases

The association between nuclear receptors and ocular diseases

DOI: 10.18632/oncotarget.15178

Ke Liu, Chang Zou,  and Bo Qin
27603-27615
Abstract  |   PDF  |  HTML  |  Order a Reprint

Tumor necrosis factor alpha is a promising circulating biomarker for the development of obstructive sleep apnea syndrome: a meta-analysis

Tumor necrosis factor alpha is a promising circulating biomarker for the development of obstructive sleep apnea syndrome: a meta-analysis

DOI: 10.18632/oncotarget.15203

Qingsheng Li,  and Xin Zheng
27616-27626
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association of polymorphisms rs1800012 in COL1A1 with sports-related tendon and ligament injuries: a meta-analysis

Association of polymorphisms rs1800012 in COL1A1 with sports-related tendon and ligament injuries: a meta-analysis

DOI: 10.18632/oncotarget.15271

Chunguang Wang, Hao Li, Kang Chen, Bing Wu,  and Haifeng Liu
27627-27634
Abstract  |   PDF  |  HTML  |  Order a Reprint

Laparoscopic cryoablation vs. percutaneous cryoablation for treatment of small renal masses: a systematic review and meta-analysis

Laparoscopic cryoablation vs. percutaneous cryoablation for treatment of small renal masses: a systematic review and meta-analysis

DOI: 10.18632/oncotarget.15273

Kehua Jiang, Kun Tang, Xiaolin Guo, Haoran Liu, Hongbo Chen, Zhiqiang Chen, Hua Xu,  and Zhangqun Ye
27635-27644
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical implications of HLA locus mismatching in unrelated donor hematopoietic cell transplantation: a meta-analysis

Clinical implications of HLA locus mismatching in unrelated donor hematopoietic cell transplantation: a meta-analysis

DOI: 10.18632/oncotarget.15291

Ruxiu Tie, Tiansong Zhang, Bo Yang, Huarui Fu, Biqing Han, Jian Yu, Yamin Tan,  and He Huang
27645-27660
Abstract  |   PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Meeting Reports

Oncogenic senescence: a multi-functional perspective

Oncogenic senescence: a multi-functional perspective

DOI: 10.18632/oncotarget.15742

Darren J. Baker, Fatouma Alimirah, Jan M. van Deursen, Judith Campisi,  and Jeffrey Hildesheim
27661-27672
Abstract  |   PDF  |  HTML  |  Order a Reprint

Corrections

Correction: Molecular profiling of peripheral blood is associated with circulating tumor cells content and poor survival in metastatic castration-resistant prostate cancer

Correction: Molecular profiling of peripheral blood is associated with circulating tumor cells content and poor survival in metastatic castration-resistant prostate cancer

DOI: 10.18632/oncotarget.17148

Mercedes Marín-Aguilera, Òscar Reig, Juan José Lozano, Natalia Jiménez, Susana García-Recio, Nadina Erill, Lydia Gaba, Andrea Tagliapietra, Vanesa Ortega, Gemma Carrera, Anna Colomer, Pedro Gascón,  and Begoña Mellado
27673-27673
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