Oncotarget

Vol 8, No 13

March 28, 2017

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About The Cover

The cover for issue 13 of Oncotarget features Figure 7A, "H&E analysis and the combined antitumor effects of a rat anti-mPD-L1 antibody +/- NHS-muIL12 on intravesical bladder tumors," from Fallon, et al.

Table of Contents

News

TNBC invasion: downstream of STAT3

TNBC invasion: downstream of STAT3

https://doi.org/10.18632/oncotarget.15259

James G. Jackson,  and Guillermina Lozano
20517-20518
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uPAR directed-imaging of head-and-neck cancer

uPAR directed-imaging of head-and-neck cancer

https://doi.org/10.18632/oncotarget.16240

Victor M. Baart, Martin C. Boonstra,  and Cornelis F.M. Sier
20519-20520
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HSP90 proteins in the scenario of tumor complexity

HSP90 proteins in the scenario of tumor complexity

https://doi.org/10.18632/oncotarget.16266

Andrea Rasola
20521-20522
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Unwanted acquired mutations in Ba/F3 transformation assays

Unwanted acquired mutations in Ba/F3 transformation assays

https://doi.org/10.18632/oncotarget.16268

Jean-Baptiste Demoulin, Guillaume Dachy,  and Florence A. Arts
20523-20524
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Priority Research Papers

Level of FACT defines the transcriptional landscape and aggressive phenotype of breast cancer cells

Level of FACT defines the transcriptional landscape and aggressive phenotype of breast cancer cells

https://doi.org/10.18632/oncotarget.15656

Daria Fleyshman, Laura Prendergast, Alfiya Safina, Geraldine Paszkiewicz, Mairead Commane, Kelsey Morgan, Kristopher Attwood,  and Katerina Gurova
20525-20542
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Metabolic reprogramming of the premalignant colonic mucosa is an early event in carcinogenesis

Metabolic reprogramming of the premalignant colonic mucosa is an early event in carcinogenesis

https://doi.org/10.18632/oncotarget.16129

Mart Dela Cruz, Sarah Ledbetter, Sanjib Chowdhury, Ashish K. Tiwari, Navneet Momi, Ramesh K. Wali, Charles Bliss, Christopher Huang, David Lichtenstein, Swati Bhattacharya, Anisha Varma-Wilson, Vadim Backman,  and Hemant K. Roy
20543-20557
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Enhanced antitumor effects by combining an IL-12/anti-DNA fusion protein with avelumab, an anti-PD-L1 antibody

Enhanced antitumor effects by combining an IL-12/anti-DNA fusion protein with avelumab, an anti-PD-L1 antibody

https://doi.org/10.18632/oncotarget.16137

Jonathan K. Fallon, Amanda J. Vandeveer, Jeffrey Schlom,  and John W. Greiner
20558-20571
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Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer

Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer

https://doi.org/10.18632/oncotarget.16244

Tristan Gallenne, Kenneth N. Ross, Nils L. Visser, Salony ., Christophe J. Desmet, Ben S. Wittner, Lodewyk F.A. Wessels, Sridhar Ramaswamy,  and Daniel S. Peeper
20572-20587
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Research Papers: Gerotarget (Focus on Aging)

Zinc finger protein ZFP36L1 promotes osteoblastic differentiation but represses adipogenic differentiation of mouse multipotent cells

Zinc finger protein ZFP36L1 promotes osteoblastic differentiation but represses adipogenic differentiation of mouse multipotent cells

https://doi.org/10.18632/oncotarget.15246

Kuo-Yun Tseng, Yi-Hsuan Chen,  and Shankung Lin
20588-20601
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Caffeine delays oocyte aging and maintains the quality of aged oocytes safely in mouse

Caffeine delays oocyte aging and maintains the quality of aged oocytes safely in mouse

https://doi.org/10.18632/oncotarget.15292

Xia Zhang, Xiaoyan Liu, Li Chen, Dan-Ya Wu, Zheng-Wen Nie, Ying-Ying Gao,  and Yi-Liang Miao
20602-20611
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Lipid and Alzheimer’s disease genes associated with healthy aging and longevity in healthy oldest-old

Lipid and Alzheimer’s disease genes associated with healthy aging and longevity in healthy oldest-old

https://doi.org/10.18632/oncotarget.15296

Lauren C. Tindale, Stephen Leach, John J. Spinelli,  and Angela R. Brooks-Wilson
20612-20621
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Research Papers: Pathology

Fibrinogen is related to long-term mortality in Chinese patients with acute coronary syndrome but failed to enhance the prognostic value of the GRACE score

Fibrinogen is related to long-term mortality in Chinese patients with acute coronary syndrome but failed to enhance the prognostic value of the GRACE score

https://doi.org/10.18632/oncotarget.15094

Yong Peng, Tian-Li Xia, Yi-Ming Li, Fang-Yang Huang, Hua Chai, Peng-Ju Wang, Wei Liu, Chen Zhang, Xiao-Bo Pu, Shi-Jian Chen, Mao Chen,  and De-Jia Huang
20622-20629
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Research Papers: Immunology

Tick-host conflict: immunoglobulin E antibodies to tick proteins in patients with anaphylaxis to tick bite

Tick-host conflict: immunoglobulin E antibodies to tick proteins in patients with anaphylaxis to tick bite

https://doi.org/10.18632/oncotarget.15243

Lourdes Mateos-Hernández, Margarita Villar, Angel Moral, Carmen García Rodríguez, Teresa Alfaya Arias, Verónica de la Osa, Francisco Feo Brito, Isabel G. Fernández de Mera, Pilar Alberdi, Francisco Ruiz-Fons, Alejandro Cabezas-Cruz, Agustín Estrada-Peña,  and José de la Fuente
20630-20644
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Axl acts as a tumor suppressor by regulating LIGHT expression in T lymphoma

Axl acts as a tumor suppressor by regulating LIGHT expression in T lymphoma

https://doi.org/10.18632/oncotarget.15830

Eun-Hee Lee, Eun-Mi Kim, Kon-Young Ji, A-Reum Park, Ha-Rim Choi, Hwa-Youn Lee, Su-Man Kim, Byung Yeoup Chung, Chul-Hong Park, Hyo Jin Choi, Young-Hyeh Ko, Hyoung-Woo Bai,  and Hyung-Sik Kang
20645-20655
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Research Papers

Differential DNA methylation patterns of polycystic ovarian syndrome in whole blood of Chinese women

Differential DNA methylation patterns of polycystic ovarian syndrome in whole blood of Chinese women

https://doi.org/10.18632/oncotarget.9327

Shuxia Li, Dongyi Zhu, Hongmei Duan, Anran Ren, Dorte Glintborg, Marianne Andersen, Vibe Skov, Mads Thomassen, Torben Kruse,  and Qihua Tan
20656-20666
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NADH autofluorescence, a new metabolic biomarker for cancer stem cells: Identification of Vitamin C and CAPE as natural products targeting “stemness”

NADH autofluorescence, a new metabolic biomarker for cancer stem cells: Identification of Vitamin C and CAPE as natural products targeting “stemness”

https://doi.org/10.18632/oncotarget.15400

Gloria Bonuccelli, Ernestina Marianna De Francesco, Rianne de Boer, Herbert B. Tanowitz,  and Michael P. Lisanti
20667-20678
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Identification of breast cancer recurrence risk factors based on functional pathways in tumor and normal tissues

Identification of breast cancer recurrence risk factors based on functional pathways in tumor and normal tissues

https://doi.org/10.18632/oncotarget.11557

Xiujie Chen, Lei Liu, Yunfeng Wang, Bo Liu, Diheng Zeng, Qing Jin, Mengjian Li, Denan Zhang, Qiuqi Liu,  and Hongbo Xie
20679-20694
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Impact of exudative diathesis induced by selenium deficiency on LncRNAs and their roles in the oxidative reduction process in broiler chick veins

Impact of exudative diathesis induced by selenium deficiency on LncRNAs and their roles in the oxidative reduction process in broiler chick veins

https://doi.org/10.18632/oncotarget.14971

Changyu Cao, Ruifeng Fan, Jinxin Zhao, Xia Zhao, Jie Yang, Ziwei Zhang,  and Shiwen Xu
20695-20705
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metformin-treated cancer cells modulate macrophage polarization through AMPK-NF-κB signaling

Metformin-treated cancer cells modulate macrophage polarization through AMPK-NF-κB signaling

https://doi.org/10.18632/oncotarget.14982

Chi-Fu Chiang, Ting-Ting Chao, Yu-Fu Su, Chia-Chen Hsu, Chu-Yen Chien, Kuo-Chou Chiu, Shine-Gwo Shiah, Chien-Hsing Lee, Shyun-Yeu Liu,  and Yi-Shing Shieh
20706-20718
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Discovery and validation of potential urinary biomarkers for bladder cancer diagnosis using a pseudotargeted GC-MS metabolomics method

Discovery and validation of potential urinary biomarkers for bladder cancer diagnosis using a pseudotargeted GC-MS metabolomics method

https://doi.org/10.18632/oncotarget.14988

Yang Zhou, Ruixiang Song, Chong Ma, Lina Zhou, Xinyu Liu, Peiyuan Yin, Zhensheng Zhang, Yinghao Sun, Chuanliang Xu, Xin Lu,  and Guowang Xu
20719-20728
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32-Phosphorus selectively delivered by listeria to pancreatic cancer demonstrates a strong therapeutic effect

32-Phosphorus selectively delivered by listeria to pancreatic cancer demonstrates a strong therapeutic effect

https://doi.org/10.18632/oncotarget.15117

Dinesh Chandra, Benson Chellakkan Selvanesan, Ziqiang Yuan, Steven K. Libutti, Wade Koba, Amanda Beck, Kun Zhu, Arturo Casadevall, Ekaterina Dadachova,  and Claudia Gravekamp
20729-20740
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway

IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway

https://doi.org/10.18632/oncotarget.15119

Xiongyan Wu, Pan Tao, Quan Zhou, Jie Li, Zhenjia Yu, Xiaofeng Wang, Jiaanfang Li, Chen Li, Min Yan, Zhenggang Zhu, Bingya Liu,  and Liping Su
20741-20750
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Overexpression of NSUN2 by DNA hypomethylation is associated with metastatic progression in human breast cancer

Overexpression of NSUN2 by DNA hypomethylation is associated with metastatic progression in human breast cancer

https://doi.org/10.18632/oncotarget.10612

Jie Yi, Ran Gao, Yu Chen, Zhuo Yang, Pei Han, Hui Zhang, Yaling Dou, Wenjing Liu, Wengong Wang, Guanhua Du, Yingchun Xu,  and Jinhua Wang
20751-20765
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Design, sythesis and evaluation of a series of 3- or 4-alkoxy substituted phenoxy derivatives as PPARs agonists

Design, sythesis and evaluation of a series of 3- or 4-alkoxy substituted phenoxy derivatives as PPARs agonists

https://doi.org/10.18632/oncotarget.15198

Jun Zhang, Xue-Jiao Wang, Xin Liu, Yi Huan, Miao-Miao Yang, Zhu-Fang Shen, Wen-Qing Jia, Zhi Jing, Shu-Qing Wang, Wei-Ren Xu, Xian-Chao Cheng,  and Run-Ling Wang
20766-20783
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Three single nucleotide polymorphisms of TNFAIP3 gene increase the risk of rheumatoid arthritis

Three single nucleotide polymorphisms of TNFAIP3 gene increase the risk of rheumatoid arthritis

https://doi.org/10.18632/oncotarget.15265

Nan Shen, Yuan Ruan, Yajun Lu, Xuefeng Jiang, Huiqing Sun, Gongming Gao, Luming Nong,  and Kewei Ren
20784-20793
Abstract  |  PDF  |  HTML  |  Order a Reprint

Age-adjusted charlson comorbidity index score as predictor of prolonged postoperative ileus in patients with colorectal cancer who underwent surgical resection

Age-adjusted charlson comorbidity index score as predictor of prolonged postoperative ileus in patients with colorectal cancer who underwent surgical resection

https://doi.org/10.18632/oncotarget.15285

Yaohua Tian, Beibei Xu, Guopei Yu, Yan Li,  and Hui Liu
20794-20801
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Understanding PSA and its derivatives in prediction of tumor volume: addressing health disparities in prostate cancer risk stratification

Understanding PSA and its derivatives in prediction of tumor volume: addressing health disparities in prostate cancer risk stratification

https://doi.org/10.18632/oncotarget.14903

Felix M. Chinea, Kirill Lyapichev, Jonathan I. Epstein, Deukwoo Kwon, Paul Taylor Smith, Alan Pollack, Richard J. Cote,  and Oleksandr N. Kryvenko
20802-20812
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Exclusive destruction of mitotic spindles in human cancer cells

Exclusive destruction of mitotic spindles in human cancer cells

https://doi.org/10.18632/oncotarget.15343

Leonid Visochek, Asher Castiel, Leonid Mittelman, Michael Elkin, Dikla Atias, Talia Golan, Shai Izraeli, Tamar Peretz,  and Malka Cohen-Armon
20813-20824
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The selective MEK1 inhibitor Selumetinib enhances the antitumor activity of everolimus against renal cell carcinoma in vitro and in vivo

The selective MEK1 inhibitor Selumetinib enhances the antitumor activity of everolimus against renal cell carcinoma in vitro and in vivo

https://doi.org/10.18632/oncotarget.15346

Yun Zou, Jianfeng Wang, Xuejiao Leng, Jiwei Huang, Wei Xue, Jin Zhang,  and Yiran Huang
20825-20833
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical significance of CSF3R, SRSF2 and SETBP1 mutations in chronic neutrophilic leukemia and chronic myelomonocytic leukemia

Clinical significance of CSF3R, SRSF2 and SETBP1 mutations in chronic neutrophilic leukemia and chronic myelomonocytic leukemia

https://doi.org/10.18632/oncotarget.15355

Yuan Ouyang, Chun Qiao, Yu Chen,  and Su-Jiang Zhang
20834-20841
Abstract  |  PDF  |  HTML  |  Order a Reprint

Effect of captopril on radiation-induced TGF-β1 secretion in EA.Hy926 human umbilical vein endothelial cells

Effect of captopril on radiation-induced TGF-β1 secretion in EA.Hy926 human umbilical vein endothelial cells

https://doi.org/10.18632/oncotarget.15356

Jingni Wei, Hui Xu, Yinyin Liu, Baiyu Li,  and Fuxiang Zhou
20842-20850
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Novel involvement of RhebL1 in sphingosylphosphorylcholine-induced keratin phosphorylation and reorganization: Binding to and activation of AKT1

Novel involvement of RhebL1 in sphingosylphosphorylcholine-induced keratin phosphorylation and reorganization: Binding to and activation of AKT1

https://doi.org/10.18632/oncotarget.15364

Hyun Ji Kim, Hyun Jung Byun, Mi Kyung Park, Eun Ji Kim, Gyeoung Jin Kang,  and Chang Hoon Lee
20851-20864
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Diabetic concentrations of metformin inhibit platelet-mediated ovarian cancer cell progression

Diabetic concentrations of metformin inhibit platelet-mediated ovarian cancer cell progression

https://doi.org/10.18632/oncotarget.15348

Rafaela Erices, Sofía Cubillos, Raúl Aravena, Felice Santoro, Monica Marquez, Renan Orellana, Carolina Ramírez, Pamela González, Patricia Fuenzalida, María Loreto Bravo, Bárbara Oliva, Sumie Kato, Carolina Ibañez, Jorge Brañes, Erasmo Bravo, Catalina Alonso, Karen García, Clemente Arab, Vicente A. Torres, Alejandro S. Godoy, Jaime Pereira, Galdo Bustos, Julio Cesar Cardenas, Mauricio A. Cuello,  and Gareth I. Owen
20865-20880
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

microRNA-210-3p depletion by CRISPR/Cas9 promoted tumorigenesis through revival of TWIST1 in renal cell carcinoma

microRNA-210-3p depletion by CRISPR/Cas9 promoted tumorigenesis through revival of TWIST1 in renal cell carcinoma

https://doi.org/10.18632/oncotarget.14930

Hirofumi Yoshino, Masaya Yonemori, Kazutaka Miyamoto, Syuichi Tatarano, Satoshi Kofuji, Nijiro Nohata, Masayuki Nakagawa,  and Hideki Enokida
20881-20894
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Resveratrol induces mitochondria-mediated, caspase-independent apoptosis in murine prostate cancer cells

Resveratrol induces mitochondria-mediated, caspase-independent apoptosis in murine prostate cancer cells

https://doi.org/10.18632/oncotarget.14947

Sanjay Kumar, Erdal Eroglu, James A. Stokes III, Karyn Scissum-Gunn, Sabita N. Saldanha, Udai P. Singh, Upender Manne, Selvarangan Ponnazhagan,  and Manoj K. Mishra
20895-20908
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells

Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells

https://doi.org/10.18632/oncotarget.14959

Xiaoqin La, Lichao Zhang, Zhuoyu Li, Peng Yang,  and Yingying Wang
20909-20924
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Polymorphisms of ESR1, UGT1A1, HCN1, MAP3K1 and CYP2B6 are associated with the prognosis of hormone receptor-positive early breast cancer

Polymorphisms of ESR1, UGT1A1, HCN1, MAP3K1 and CYP2B6 are associated with the prognosis of hormone receptor-positive early breast cancer

https://doi.org/10.18632/oncotarget.14995

Sung-Hsin Kuo, Shi-Yi Yang, San-Lin You, Huang-Chun Lien, Ching-Hung Lin, Po-Han Lin,  and Chiun-Sheng Huang
20925-20938
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Control of long-distance cell-to-cell communication and autophagosome transfer in squamous cell carcinoma via tunneling nanotubes

Control of long-distance cell-to-cell communication and autophagosome transfer in squamous cell carcinoma via tunneling nanotubes

https://doi.org/10.18632/oncotarget.15467

Inés Sáenz-de-Santa-María, Cristóbal Bernardo-Castiñeira, Eduardo Enciso, Inmaculada García-Moreno, Jose Luis Chiara, Carlos Suarez,  and María-Dolores Chiara
20939-20960
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Afatinib radiosensitizes head and neck squamous cell carcinoma cells by targeting cancer stem cells

Afatinib radiosensitizes head and neck squamous cell carcinoma cells by targeting cancer stem cells

https://doi.org/10.18632/oncotarget.15468

Muzafar A. Macha, Satyanarayana Rachagani, Asif Khurshid Qazi, Rahat Jahan, Suprit Gupta, Anery Patel, Parthasarathy Seshacharyulu, Chi Lin, Sicong Li, Shuo Wang, Vivek Verma, Shosei Kishida, Michiko Kishida, Norifumi Nakamura, Toshiro Kibe, William M. Lydiatt, Russell B. Smith, Apar K. Ganti, Dwight T. Jones, Surinder K. Batra,  and Maneesh Jain
20961-20973
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

mTOR inhibitors activate PERK signaling and favor viability of gastrointestinal neuroendocrine cell lines

mTOR inhibitors activate PERK signaling and favor viability of gastrointestinal neuroendocrine cell lines

https://doi.org/10.18632/oncotarget.15469

Patricia Freis, Julien Bollard, Justine Lebeau, Patrick Massoma, Joëlle Fauvre, Cécile Vercherat, Thomas Walter, Serge Manié, Colette Roche, Jean-Yves Scoazec,  and Carole Ferraro-Peyret
20974-20987
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Drp1-dependent mitophagy protects against cisplatin-induced apoptosis of renal tubular epithelial cells by improving mitochondrial function

Drp1-dependent mitophagy protects against cisplatin-induced apoptosis of renal tubular epithelial cells by improving mitochondrial function

https://doi.org/10.18632/oncotarget.15470

Chuanyan Zhao, Zhuyun Chen, Jia Qi, Suyan Duan, Zhimin Huang, Chengning Zhang, Lin Wu, Ming Zeng, Bo Zhang, Ningning Wang, Huijuan Mao, Aihua Zhang, Changying Xing,  and Yanggang Yuan
20988-21000
Abstract  |  PDF  |  HTML  |  Order a Reprint

The PIAS3-Smurf2 sumoylation pathway suppresses breast cancer organoid invasiveness

The PIAS3-Smurf2 sumoylation pathway suppresses breast cancer organoid invasiveness

https://doi.org/10.18632/oncotarget.15471

Amrita Singh Chandhoke, Ayan Chanda, Kunal Karve, Lili Deng,  and Shirin Bonni
21001-21014
Abstract  |  PDF  |  HTML  |  Order a Reprint

Imidazoline I2 receptor inhibitor idazoxan regulates the progression of hepatic fibrosis via Akt-Nrf2-Smad2/3 signaling pathway

Imidazoline I2 receptor inhibitor idazoxan regulates the progression of hepatic fibrosis via Akt-Nrf2-Smad2/3 signaling pathway

https://doi.org/10.18632/oncotarget.15472

Li Xuanfei, Chen Hao, Yi Zhujun, Liu Yanming,  and Gong Jianping
21015-21030
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The role of hesperetin on osteogenesis of human mesenchymal stem cells and its function in bone regeneration

The role of hesperetin on osteogenesis of human mesenchymal stem cells and its function in bone regeneration

https://doi.org/10.18632/oncotarget.15473

Deting Xue, Erman Chen, Wei Zhang, Xiang Gao, Shengdong Wang, Qiang Zheng, Zhijun Pan, Hang Li,  and Ling Liu
21031-21043
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Relaxin abrogates renal interstitial fibrosis by regulating macrophage polarization via inhibition of Toll-like receptor 4 signaling

Relaxin abrogates renal interstitial fibrosis by regulating macrophage polarization via inhibition of Toll-like receptor 4 signaling

https://doi.org/10.18632/oncotarget.15483

Lei Chen, Ming-Lei Sha, Deng Li, Yi-Ping Zhu, Xing-Jie Wang, Chen-Yi Jiang, Shu-Jie Xia,  and Yi Shao
21044-21053
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Real-time near-infrared fluorescence imaging using cRGD-ZW800-1 for intraoperative visualization of multiple cancer types

Real-time near-infrared fluorescence imaging using cRGD-ZW800-1 for intraoperative visualization of multiple cancer types

https://doi.org/10.18632/oncotarget.15486

Henricus J.M. Handgraaf, Martin C. Boonstra, Hendrica A.J.M. Prevoo, Joeri Kuil, Mark W. Bordo, Leonora S.F. Boogerd, Babs G. Sibinga Mulder, Cornelis F.M. Sier, Maaike L. Vinkenburg-van Slooten, A. Rob P.M. Valentijn, Jacobus Burggraaf, Cornelis J.H. van de Velde, John V. Frangioni,  and Alexander L. Vahrmeijer
21054-21066
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Antimicrobial peptide Epinecidin-1 promotes complete skin regeneration of methicillin-resistant Staphylococcus aureus-infected burn wounds in a swine model

Antimicrobial peptide Epinecidin-1 promotes complete skin regeneration of methicillin-resistant Staphylococcus aureus-infected burn wounds in a swine model

https://doi.org/10.18632/oncotarget.15042

Han-Ning Huang, Chieh-Yu Pan, Hung-Yi Wu,  and Jyh-Yih Chen
21067-21080
Abstract  |  PDF  |  HTML  |  Order a Reprint

Epigenetic silencing of miR-520c leads to induced S100A4 expression and its mediated colorectal cancer progression

Epigenetic silencing of miR-520c leads to induced S100A4 expression and its mediated colorectal cancer progression

https://doi.org/10.18632/oncotarget.15499

Giridhar Mudduluru, Katharina Ilm, Steffen Fuchs,  and Ulrike Stein
21081-21094
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comprehensive analysis of differentially expressed profiles of lncRNAs and construction of miR-133b mediated ceRNA network in colorectal cancer

Comprehensive analysis of differentially expressed profiles of lncRNAs and construction of miR-133b mediated ceRNA network in colorectal cancer

https://doi.org/10.18632/oncotarget.15045

Hao Wu, Runliu Wu, Miao Chen, Daojiang Li, Jing Dai, Yi Zhang, Kai Gao, Jun Yu, Gui Hu, Yihang Guo, Changwei Lin,  and Xiaorong Li
21095-21105
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Differential expression of M3 muscarinic receptors in progressive colon neoplasia and metastasis

Differential expression of M3 muscarinic receptors in progressive colon neoplasia and metastasis

https://doi.org/10.18632/oncotarget.15500

Kunrong Cheng, Aaron C. Shang, Cinthia B. Drachenberg, Min Zhan,  and Jean-Pierre Raufman
21106-21114
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Acute lymphoblastic leukemia cells are sensitive to disturbances in protein homeostasis induced by proteasome deubiquitinase inhibition

Acute lymphoblastic leukemia cells are sensitive to disturbances in protein homeostasis induced by proteasome deubiquitinase inhibition

https://doi.org/10.18632/oncotarget.15501

Magdalena Mazurkiewicz, Ellin-Kristina Hillert, Xin Wang, Paola Pellegrini, Maria Hägg Olofsson, Karthik Selvaraju, Padraig D’Arcy,  and Stig Linder
21115-21127
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Pevonedistat, a Nedd8-activating enzyme inhibitor, sensitizes neoplastic B-cells to death receptor-mediated apoptosis

Pevonedistat, a Nedd8-activating enzyme inhibitor, sensitizes neoplastic B-cells to death receptor-mediated apoptosis

https://doi.org/10.18632/oncotarget.15050

Cody Paiva, J. Claire Godbersen, Taylor Rowland, Olga V. Danilova, Christopher Danes, Allison Berger,  and Alexey V. Danilov
21128-21139
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Annonaceous acetogenins mediated up-regulation of Notch2 exerts growth inhibition in human gastric cancer cells in vitro

Annonaceous acetogenins mediated up-regulation of Notch2 exerts growth inhibition in human gastric cancer cells in vitro

https://doi.org/10.18632/oncotarget.15502

Yan Li, Jianbin Ye, Zhongbiao Chen, Junjie Wen, Fei Li, Pengpeng Su, Yanqing Lin, Bingxin Hu, Danlin Wu, Lijun Ning, Qi Xue, Hongxiang Gu,  and Yunshan Ning
21140-21152
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Proteasome inhibition enhances the efficacy of volasertib-induced mitotic arrest in AML in vitro and prolongs survival in vivo

Proteasome inhibition enhances the efficacy of volasertib-induced mitotic arrest in AML in vitro and prolongs survival in vivo

https://doi.org/10.18632/oncotarget.15503

Dominik Schnerch, Julia Schüler, Marie Follo, Julia Felthaus, Dagmar Wider, Kathrin Klingner, Christine Greil, Justus Duyster, Monika Engelhardt,  and Ralph Wäsch
21153-21166
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CDKN2B gene rs1063192 polymorphism decreases the risk of glaucoma

CDKN2B gene rs1063192 polymorphism decreases the risk of glaucoma

https://doi.org/10.18632/oncotarget.15504

Zhenxian Hu,  and Chenliang He
21167-21176
Abstract  |  PDF  |  HTML  |  Order a Reprint

Synergistic effects of the immune checkpoint inhibitor CTLA-4 combined with the growth inhibitor lycorine in a mouse model of renal cell carcinoma

Synergistic effects of the immune checkpoint inhibitor CTLA-4 combined with the growth inhibitor lycorine in a mouse model of renal cell carcinoma

https://doi.org/10.18632/oncotarget.15505

Xiezhao Li, Peng Xu, Chongshan Wang, Naijin Xu, Abai Xu, Yawen Xu, Takuya Sadahira, Motoo Araki, Koichiro Wada, Eiji Matsuura, Masami Watanabe, Junxia Zheng, Pinghua Sun, Peng Huang, Yasutomo Nasu,  and Chunxiao Liu
21177-21186
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MCMDA: Matrix completion for MiRNA-disease association prediction

MCMDA: Matrix completion for MiRNA-disease association prediction

https://doi.org/10.18632/oncotarget.15061

Jian-Qiang Li, Zhi-Hao Rong, Xing Chen, Gui-Ying Yan,  and Zhu-Hong You
21187-21199
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Rap2b siRNA significantly enhances the anticancer therapeutic efficacy of Adriamycin in a gold nanoshell-based drug/gene co-delivery system

Rap2b siRNA significantly enhances the anticancer therapeutic efficacy of Adriamycin in a gold nanoshell-based drug/gene co-delivery system

https://doi.org/10.18632/oncotarget.15508

Li Ding, Ruonan Sun,  and Xinyue Zhang
21200-21211
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of patient-specific and tumor-shared T cell receptor sequences in renal cell carcinoma patients

Identification of patient-specific and tumor-shared T cell receptor sequences in renal cell carcinoma patients

https://doi.org/10.18632/oncotarget.15064

Chiara Massa, Harlan Robins, Cindy Desmarais, Dagmar Riemann, Corinna Fahldieck, Paolo Fornara,  and Barbara Seliger
21212-21228
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TRAP1 protein signature predicts outcome in human metastatic colorectal carcinoma

TRAP1 protein signature predicts outcome in human metastatic colorectal carcinoma

https://doi.org/10.18632/oncotarget.15070

Francesca Maddalena, Vittorio Simeon, Giulia Vita, Annamaria Bochicchio, Luciana Possidente, Lorenza Sisinni, Giacomo Lettini, Valentina Condelli, Danilo Swann Matassa, Valeria Li Bergolis, Alberto Fersini, Sante Romito, Michele Aieta, Antonio Ambrosi, Franca Esposito,  and Matteo Landriscina
21229-21240
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Myocardial protection from ischemia/reperfusion injury by exogenous galanin fragment

Myocardial protection from ischemia/reperfusion injury by exogenous galanin fragment

https://doi.org/10.18632/oncotarget.15071

Andrei Timotin, Oleg Pisarenko, Maria Sidorova, Irina Studneva, Valentin Shulzhenko, Marina Palkeeva, Larisa Serebryakova, Aleksander Molokoedov, Oksana Veselova, Mathieu Cinato, Helene Tronchere, Frederic Boal,  and Oksana Kunduzova
21241-21252
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Variations in the bitterness perception-related genes TAS2R38 and CA6 modify the risk for colorectal cancer in Koreans

Variations in the bitterness perception-related genes TAS2R38 and CA6 modify the risk for colorectal cancer in Koreans

https://doi.org/10.18632/oncotarget.15512

Jeong-Hwa Choi, Jeonghee Lee, Jae Hwan Oh, Hee Jin Chang, Dae Kyung Sohn, Aesun Shin,  and Jeongseon Kim
21253-21265
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Aminopeptidase A initiates tumorigenesis and enhances tumor cell stemness via TWIST1 upregulation in colorectal cancer

Aminopeptidase A initiates tumorigenesis and enhances tumor cell stemness via TWIST1 upregulation in colorectal cancer

https://doi.org/10.18632/oncotarget.15072

Hui-Yu Chuang, Jeng-Kae Jiang, Muh-Hwa Yang, Hsei-Wei Wang, Ming-Chun Li, Chan-Yen Tsai, Yau-Yun Jhang,  and Jason C. Huang
21266-21280
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genome-scale analysis identifies GJB2 and ERO1LB as prognosis markers in patients with pancreatic cancer

Genome-scale analysis identifies GJB2 and ERO1LB as prognosis markers in patients with pancreatic cancer

https://doi.org/10.18632/oncotarget.15068

Tao Zhu, Yuan-Feng Gao, Yi-Xin Chen, Zhi-Bin Wang, Ji-Ye Yin, Xiao-Yuan Mao, Xi Li, Wei Zhang, Hong-Hao Zhou,  and Zhao-Qian Liu
21281-21289
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification and analysis of mutational hotspots in oncogenes and tumour suppressors

Identification and analysis of mutational hotspots in oncogenes and tumour suppressors

https://doi.org/10.18632/oncotarget.15514

Hanadi Baeissa, Graeme Benstead-Hume, Christopher J. Richardson,  and Frances M.G. Pearl
21290-21304
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Granulocyte colony-stimulating factor enhances the therapeutic efficacy of bone marrow mesenchymal stem cell transplantation in rats with experimental acute pancreatitis

Granulocyte colony-stimulating factor enhances the therapeutic efficacy of bone marrow mesenchymal stem cell transplantation in rats with experimental acute pancreatitis

https://doi.org/10.18632/oncotarget.15515

Bo Qu, Yanjie Chu, Fang Zhu, Beibei Wang, Ting Liu, Bo Yu,  and Shizhu Jin
21305-21314
Abstract  |  PDF  |  HTML  |  Order a Reprint

Histone lysine methyltransferase G9a is a novel epigenetic target for the treatment of hepatocellular carcinoma

Histone lysine methyltransferase G9a is a novel epigenetic target for the treatment of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.15528

Masayuki Yokoyama, Tetsuhiro Chiba, Yoh Zen, Motohiko Oshima, Yuko Kusakabe, Yoshiko Noguchi, Kaori Yuki, Shuhei Koide, Shiro Tara, Atsunori Saraya, Kazumasa Aoyama, Naoya Mimura, Satoru Miyagi, Masanori Inoue, Toru Wakamatsu, Tomoko Saito, Sadahisa Ogasawara, Eiichiro Suzuki, Yoshihiko Ooka, Akinobu Tawada, Masayuki Otsuka, Masaru Miyazaki, Osamu Yokosuka,  and Atsushi Iwama
21315-21326
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel pathogenic splice acceptor site germline mutation in intron 14 of the APC gene in a Chinese family with familial adenomatous polyposis

A novel pathogenic splice acceptor site germline mutation in intron 14 of the APC gene in a Chinese family with familial adenomatous polyposis

https://doi.org/10.18632/oncotarget.15570

Dan Wang, Shengyun Liang, Zhao Zhang, Guoru Zhao, Yuan Hu, Shengran Liang, Xipeng Zhang,  and Santasree Banerjee
21327-21335
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Autophagy is highly targeted among host comparative proteomes during infection with different virulent RABV strains

Autophagy is highly targeted among host comparative proteomes during infection with different virulent RABV strains

https://doi.org/10.18632/oncotarget.15184

Ling Li, Hongli Jin, Hualei Wang, Zengguo Cao, Na Feng, Jianzhong Wang, Yongkun Zhao, Xuexing Zheng, Pengfei Hou, Nan Li, Hang Chi, Pei Huang, Cuicui Jiao, Qian Li, Lina Wang, Tiecheng Wang, Weiyang Sun, Yuwei Gao, Changchun Tu, Guixue Hu, Songtao Yang,  and Xianzhu Xia
21336-21350
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clerosterol from vinegar-baked radix bupleuri modifies drug transport

Clerosterol from vinegar-baked radix bupleuri modifies drug transport

https://doi.org/10.18632/oncotarget.15212

Ya Zhao, Li-Min Feng, Li-Juan Liu, Xian Zhang,  and Rui-Zhi Zhao
21351-21361
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-34a targets epithelial to mesenchymal transition-inducing transcription factors (EMT-TFs) and inhibits breast cancer cell migration and invasion

MicroRNA-34a targets epithelial to mesenchymal transition-inducing transcription factors (EMT-TFs) and inhibits breast cancer cell migration and invasion

https://doi.org/10.18632/oncotarget.15214

Saber Imani, Chunli Wei, Jingliang Cheng, Md. Asaduzzaman Khan, Shangyi Fu, Luquan Yang, Mousumi Tania, Xianqin Zhang, Xiuli Xiao, Xianning Zhang,  and Junjiang Fu
21362-21379
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-494-3p overexpression promotes megakaryocytopoiesis in primary myelofibrosis hematopoietic stem/progenitor cells by targeting SOCS6

miR-494-3p overexpression promotes megakaryocytopoiesis in primary myelofibrosis hematopoietic stem/progenitor cells by targeting SOCS6

https://doi.org/10.18632/oncotarget.15226

Sebastiano Rontauroli, Ruggiero Norfo, Valentina Pennucci, Roberta Zini, Samantha Ruberti, Elisa Bianchi, Simona Salati, Zelia Prudente, Chiara Rossi, Vittorio Rosti, Paola Guglielmelli, Giovanni Barosi, Alessandro Vannucchi, Enrico Tagliafico,  and Rossella Manfredini
21380-21397
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

M2 polarization of macrophages facilitates arsenic-induced cell transformation of lung epithelial cells

M2 polarization of macrophages facilitates arsenic-induced cell transformation of lung epithelial cells

https://doi.org/10.18632/oncotarget.15232

Jiajun Cui, Wenhua Xu, Jian Chen, Hui Li, Lu Dai, Jacqueline A. Frank, Shaojun Peng, Siying Wang,  and Gang Chen
21398-21409
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Long non-coding RNA HULC as a potential prognostic biomarker in human cancers: a meta-analysis

Long non-coding RNA HULC as a potential prognostic biomarker in human cancers: a meta-analysis

https://doi.org/10.18632/oncotarget.15247

Yang-Hua Fan, Miao-Jing Wu, Yuan Jiang, Minhua Ye, Shi-Gang Lu, Lei Wu,  and Xin-Gen Zhu
21410-21417
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Blockade of Rho-associated protein kinase (ROCK) inhibits the contractility and invasion potential of cancer stem like cells

Blockade of Rho-associated protein kinase (ROCK) inhibits the contractility and invasion potential of cancer stem like cells

https://doi.org/10.18632/oncotarget.15248

Srisathya Srinivasan, Vandhana Ashok, Sagarajit Mohanty, Alakesh Das, Sreya Das, Sushant Kumar, Shamik Sen,  and Rahul Purwar
21418-21428
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RASSF1A promoter methylation in high-grade serous ovarian cancer: A direct comparison study in primary tumors, adjacent morphologically tumor cell-free tissues and paired circulating tumor DNA

RASSF1A promoter methylation in high-grade serous ovarian cancer: A direct comparison study in primary tumors, adjacent morphologically tumor cell-free tissues and paired circulating tumor DNA

https://doi.org/10.18632/oncotarget.15249

Lydia Giannopoulou, Issam Chebouti, Kitty Pavlakis, Sabine Kasimir-Bauer,  and Evi S. Lianidou
21429-21443
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PRSS3 is a prognostic marker in invasive ductal carcinoma of the breast

PRSS3 is a prognostic marker in invasive ductal carcinoma of the breast

https://doi.org/10.18632/oncotarget.15590

Li Qian, Xiangxiang Gao, Hua Huang, Shumin Lu, Yin Cai, Yu Hua, Yifei Liu,  and Jianguo Zhang
21444-21453
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Grifolin exhibits anti-cancer activity by inhibiting the development and invasion of gastric tumor cells

Grifolin exhibits anti-cancer activity by inhibiting the development and invasion of gastric tumor cells

https://doi.org/10.18632/oncotarget.15250

Zijian Wu,  and Ying Li
21454-21460
Abstract  |  PDF  |  HTML  |  Order a Reprint

miR-106b-5p promotes renal cell carcinoma aggressiveness and stem-cell-like phenotype by activating Wnt/β-catenin signalling

miR-106b-5p promotes renal cell carcinoma aggressiveness and stem-cell-like phenotype by activating Wnt/β-catenin signalling

https://doi.org/10.18632/oncotarget.15591

Jun Lu, Jin-Huan Wei, Zi-Hao Feng, Zhen-Hua Chen, Yong-Qian Wang, Yong Huang, Yong Fang, Yan-Ping Liang, Jun-Jie Cen, Yi-Hui Pan, Bing Liao, Wen-Fang Chen, Wei Chen,  and Jun-Hang Luo
21461-21471
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Critically short telomeres and toxicity of chemotherapy in early breast cancer

Critically short telomeres and toxicity of chemotherapy in early breast cancer

https://doi.org/10.18632/oncotarget.15592

Miguel Quintela-Fandino, Nora Soberon, Ana Lluch, Luis Manso, Isabel Calvo, Javier Cortes, Fernando Moreno-Antón, Miguel Gil-Gil, Noelia Martinez-Jánez, Antonio Gonzalez-Martin, Encarna Adrover, Raquel de Andres, Gemma Viñas, Antonio Llombart-Cussac, Emilio Alba, Silvana Mouron, Juan Guerra, Begoña Bermejo, Esther Zamora, Jose Angel García-Saenz, Sonia Pernas Simon, Eva Carrasco, María José Escudero, Ruth Campo, Ramón Colomer,  and Maria A. Blasco
21472-21482
Abstract  |  PDF  |  HTML  |  Order a Reprint

Lynch syndrome-related small intestinal adenocarcinomas

Lynch syndrome-related small intestinal adenocarcinomas

https://doi.org/10.18632/oncotarget.15277

Sun-Young Jun, Eui-Jin Lee, Mi-Ju Kim, Sung Min Chun, Young Kyung Bae, Soon Uk Hong, Jene Choi, Joon Mee Kim, Kee-Taek Jang, Jung Yeon Kim, Gwang Il Kim, Soo Jin Jung, Ghilsuk Yoon,  and Seung-Mo Hong
21483-21500
Abstract  |  PDF  |  HTML  |  Order a Reprint

NRIP/DCAF6 stabilizes the androgen receptor protein by displacing DDB2 from the CUL4A-DDB1 E3 ligase complex in prostate cancer

NRIP/DCAF6 stabilizes the androgen receptor protein by displacing DDB2 from the CUL4A-DDB1 E3 ligase complex in prostate cancer

https://doi.org/10.18632/oncotarget.15308

Hsin-Hsiung Chen, Ping Fan, Szu-Wei Chang, Yeou-Ping Tsao, Hsiang-Po Huang,  and Show-Li Chen
21501-21515
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The combination of circulating long noncoding RNAs AK001058, INHBA-AS1, MIR4435-2HG, and CEBPA-AS1 fragments in plasma serve as diagnostic markers for gastric cancer

The combination of circulating long noncoding RNAs AK001058, INHBA-AS1, MIR4435-2HG, and CEBPA-AS1 fragments in plasma serve as diagnostic markers for gastric cancer

https://doi.org/10.18632/oncotarget.15628

Dong Ke, Hanwei Li, Yi Zhang, Yinghong An, Hanjiang Fu, Xuedong Fang,  and Xiaofei Zheng
21516-21525
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CD163 as a marker of M2 macrophage, contribute to predict aggressiveness and prognosis of Kazakh esophageal squamous cell carcinoma

CD163 as a marker of M2 macrophage, contribute to predict aggressiveness and prognosis of Kazakh esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.15630

Jian Ming Hu, Kai Liu, Ji Hong Liu, Xian Li Jiang, Xue Li Wang, Yun Zhao Chen, Shu Gang Li, Hong Zou, Li Juan Pang, Chun Xia Liu, Xiao Bin Cui, Lan Yang, Jin Zhao, Xi Hua Shen, Jin Fang Jiang, Wei Hua Liang, Xiang Lin Yuan,  and Feng Li
21526-21538
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ipilimumab treatment decreases monocytic MDSCs and increases CD8 effector memory T cells in long-term survivors with advanced melanoma

Ipilimumab treatment decreases monocytic MDSCs and increases CD8 effector memory T cells in long-term survivors with advanced melanoma

https://doi.org/10.18632/oncotarget.15368

Yago Pico de Coana, Maria Wolodarski, Isabel Poschke, Yuya Yoshimoto, Yuan Yang, Maria Nystrom, Ulrika Edback, Suzanne Eghyazi Brage, Andreas Lundqvist, Giuseppe V. Masucci, Johan Hansson,  and Rolf Kiessling
21539-21553
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genomic imbalances are involved in miR-30c and let-7a deregulation in ovarian tumors: implications for HMGA2 expression

Genomic imbalances are involved in miR-30c and let-7a deregulation in ovarian tumors: implications for HMGA2 expression

https://doi.org/10.18632/oncotarget.15795

Antonio Agostini, Marta Brunetti, Ben Davidson, Claes G. Tropé, Sverre Heim, Ioannis Panagopoulos,  and Francesca Micci
21554-21560
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MMP8 polymorphism is associated with susceptibility to osteonecrosis of the femoral head in a Chinese Han population

MMP8 polymorphism is associated with susceptibility to osteonecrosis of the femoral head in a Chinese Han population

https://doi.org/10.18632/oncotarget.15371

Feimeng An, Jieli Du, Yuju Cao, Jianping Shi, Yongchang Guo, Tianbo Jin, Jian Li, Junyu Chen, Ping Li, Mei Dong, Guoqiang Wang,  and Jianzhong Wang
21561-21566
Abstract  |  PDF  |  HTML  |  Order a Reprint

Target of obstructive sleep apnea syndrome merge lung cancer: based on big data platform

Target of obstructive sleep apnea syndrome merge lung cancer: based on big data platform

https://doi.org/10.18632/oncotarget.15372

Lifeng Li, Jingli Lu, Wenhua Xue, Liping Wang, Yunkai Zhai, Zhirui Fan, Ge Wu, Feifei Fan, Jieyao Li, Chaoqi Zhang, Yi Zhang,  and Jie Zhao
21567-21578
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways

Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways

https://doi.org/10.18632/oncotarget.15375

Reetobrata Basu, Shiyong Wu,  and John J. Kopchick
21579-21598
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reappraisal of XRCC1 Arg194Trp polymorphism and glioma risk: a cumulative meta-analysis

Reappraisal of XRCC1 Arg194Trp polymorphism and glioma risk: a cumulative meta-analysis

https://doi.org/10.18632/oncotarget.15376

Jun-Ti Lu, Ai-Ping Deng, Juan Song, Li Zhang,  and Jie Luo
21599-21608
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1

The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1

https://doi.org/10.18632/oncotarget.15450

Michele Cioffi, Sara M. Trabulo, Mireia Vallespinos, Deepak Raj, Tony Bou Kheir, Meng-Lay Lin, Julfa Begum, Ann-Marie Baker, Ala Amgheib, Jaimy Saif, Manuel Perez, Joaquim Soriano, Manuel Desco, Maria Victoria Gomez-Gaviro, Lorena Cusso, Diego Megias, Alexandra Aicher,  and Christopher Heeschen
21609-21625
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ONC201 activates ER stress to inhibit the growth of triple-negative breast cancer cells

ONC201 activates ER stress to inhibit the growth of triple-negative breast cancer cells

https://doi.org/10.18632/oncotarget.15451

Xun Yuan, Dhonghyo Kho, Jing Xu, Ambikai Gajan, Kongming Wu,  and Gen Sheng Wu
21626-21638
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical significance of detecting circulating tumor cells in colorectal cancer using subtraction enrichment and immunostaining-fluorescence in situ hybridization (SE-iFISH)

Clinical significance of detecting circulating tumor cells in colorectal cancer using subtraction enrichment and immunostaining-fluorescence in situ hybridization (SE-iFISH)

https://doi.org/10.18632/oncotarget.15452

Wei Wu, Zhenzhen Zhang, Xian Hua Gao, Zhen Shen, Yan Jing, Haibo Lu, Heng Li, Xiaoye Yang, Xiangbin Cui, Yuqing Li, Zheng Lou, Peng Liu, Cun Zhang,  and Wei Zhang
21639-21649
Abstract  |  PDF  |  HTML  |  Order a Reprint

TGF-β–independent CTGF induction regulates cell adhesion mediated drug resistance by increasing collagen I in HCC

TGF-β–independent CTGF induction regulates cell adhesion mediated drug resistance by increasing collagen I in HCC

https://doi.org/10.18632/oncotarget.15521

Yeonhwa Song, Jin-Sun Kim, Eun Kyung Choi, Joon Kim, Kang Mo Kim,  and Haeng Ran Seo
21650-21662
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Annexin A13 promotes tumor cell invasion in vitro and is associated with metastasis in human colorectal cancer

Annexin A13 promotes tumor cell invasion in vitro and is associated with metastasis in human colorectal cancer

https://doi.org/10.18632/oncotarget.15523

Guozhong Jiang, Pengju Wang, Weiwei Wang, Wencai Li, Liping Dai,  and Kuisheng Chen
21663-21673
Abstract  |  PDF  |  HTML  |  Order a Reprint

Genistein inhibits the growth and regulates the migration and invasion abilities of melanoma cells via the FAK/paxillin and MAPK pathways

Genistein inhibits the growth and regulates the migration and invasion abilities of melanoma cells via the FAK/paxillin and MAPK pathways

https://doi.org/10.18632/oncotarget.15535

Shuna Cui, Juan Wang, Qingqing Wu, Jing Qian, Changshui Yang,  and Ping Bo
21674-21691
Abstract  |  PDF  |  HTML  |  Order a Reprint

ATM kinase sustains breast cancer stem-like cells by promoting ATG4C expression and autophagy

ATM kinase sustains breast cancer stem-like cells by promoting ATG4C expression and autophagy

https://doi.org/10.18632/oncotarget.15537

Martina Antonelli, Flavie Strappazzon, Ivan Arisi, Rossella Brandi, Mara D'Onofrio, Manolo Sambucci, Gwenola Manic, Ilio Vitale, Daniela Barilà,  and Venturina Stagni
21692-21709
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Kinase analysis of penile squamous cell carcinoma on multiple platforms to identify potential therapeutic targets

Kinase analysis of penile squamous cell carcinoma on multiple platforms to identify potential therapeutic targets

https://doi.org/10.18632/oncotarget.15558

Eddy S. Yang, Christopher D. Willey, Amitkumar Mehta, Michael R. Crowley, David K. Crossman, Dongquan Chen, Joshua C. Anderson, Gurudatta Naik, Deborah L. Della Manna, Tiffiny S. Cooper,  and Guru Sonpavde
21710-21718
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-503-5p confers drug resistance by targeting PUMA in colorectal carcinoma

miR-503-5p confers drug resistance by targeting PUMA in colorectal carcinoma

https://doi.org/10.18632/oncotarget.15559

Ke Xu, Guo Chen, Yanyan Qiu, Zeting Yuan, Hongchang Li, Xia Yuan, Jian Sun, Jianhua Xu, Xin Liang,  and Peihao Yin
21719-21732
Abstract  |  PDF  |  HTML  |  Order a Reprint

Mitotic read-out genes confer poor outcome in luminal A breast cancer tumors

Mitotic read-out genes confer poor outcome in luminal A breast cancer tumors

https://doi.org/10.18632/oncotarget.15562

Javier Pérez-Peña, Ana Alcaraz-Sanabria, Cristina Nieto-Jiménez, Raquel Páez, Verónica Corrales-Sánchez, Leticia Serrano-Oviedo, Vikram B. Wali, Gauri A. Patwardhan, Eitan Amir, Balázs Győrffy, Atanasio Pandiella,  and Alberto Ocaña
21733-21740
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preclinical therapeutic efficacy of a novel blood-brain barrier-penetrant dual PI3K/mTOR inhibitor with preferential response in PI3K/PTEN mutant glioma

Preclinical therapeutic efficacy of a novel blood-brain barrier-penetrant dual PI3K/mTOR inhibitor with preferential response in PI3K/PTEN mutant glioma

https://doi.org/10.18632/oncotarget.15566

Dimpy Koul, Shuzhen Wang, Shaofang Wu, Norihiko Saito, Siyuan Zheng, Feng Gao, Isha Kaul, Masaki Setoguchi, Kiyoshi Nakayama, Kumiko Koyama, Yoshinobu Shiose, Erik P. Sulman, Yasuhide Hirota,  and W.K. Alfred Yung
21741-21753
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The addition of celecoxib improves the antitumor effect of cetuximab in colorectal cancer: role of EGFR-RAS-FOXM1-β-catenin signaling axis

The addition of celecoxib improves the antitumor effect of cetuximab in colorectal cancer: role of EGFR-RAS-FOXM1-β-catenin signaling axis

https://doi.org/10.18632/oncotarget.15567

Araceli Valverde, Jon Peñarando, Amanda Cañas, Laura M. López-Sánchez, Francisco Conde, Silvia Guil-Luna, Vanessa Hernández, Carlos Villar, Cristina Morales-Estévez, Juan de la Haba-Rodríguez, Enrique Aranda,  and Antonio Rodríguez-Ariza
21754-21769
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Next generation sequencing of extraskeletal myxoid chondrosarcoma

Next generation sequencing of extraskeletal myxoid chondrosarcoma

https://doi.org/10.18632/oncotarget.15568

Elizabeth J. Davis, Yi-Mi Wu, Dan Robinson, Scott M. Schuetze, Laurence H. Baker, Jyoti Athanikar, Xuhong Cao, Lakshmi P. Kunju, Arul M. Chinnaiyan,  and Rashmi Chugh
21770-21777
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Vitamin D and VDR in cancer cachexia and muscle regeneration

Vitamin D and VDR in cancer cachexia and muscle regeneration

https://doi.org/10.18632/oncotarget.15583

Andrea Camperi, Fabrizio Pin, Domiziana Costamagna, Fabio Penna, Maria Lopez Menduina, Zaira Aversa, Teresa Zimmers, Roberto Verzaro, Raffaella Fittipaldi, Giuseppina Caretti, Francesco Maria Baccino, Maurizio Muscaritoli,  and Paola Costelli
21778-21793
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic role of programmed-death ligand 1 (PD-L1) expressing tumor infiltrating lymphocytes in testicular germ cell tumors

Prognostic role of programmed-death ligand 1 (PD-L1) expressing tumor infiltrating lymphocytes in testicular germ cell tumors

https://doi.org/10.18632/oncotarget.15585

Michal Chovanec, Zuzana Cierna, Viera Miskovska, Katarina Machalekova, Daniela Svetlovska, Katarina Kalavska, Katarina Rejlekova, Stanislav Spanik, Karol Kajo, Pavel Babal, Jozef Mardiak,  and Michal Mego
21794-21805
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Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer

Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer

https://doi.org/10.18632/oncotarget.15586

Riley A. Hampsch, Kevin Shee, Darcy Bates, Lionel D. Lewis, Laurent Désiré, Bertrand Leblond, Eugene Demidenko, Kurtis Stefan, Yina H. Huang,  and Todd W. Miller
21806-21817
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HES1 promotes extracellular matrix protein expression and inhibits proliferation and migration in human trabecular meshwork cells under oxidative stress

HES1 promotes extracellular matrix protein expression and inhibits proliferation and migration in human trabecular meshwork cells under oxidative stress

https://doi.org/10.18632/oncotarget.15631

Linqi Xu, Yan Zhang, Ruru Guo, Wencui Shen, Yan Qi, Qingsong Wang, Zhenglong Guo, Chen Qi, Haifang Yin,  and Jiantao Wang
21818-21833
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PIF* promotes brain re-myelination locally while regulating systemic inflammation- clinically relevant multiple sclerosis M.smegmatis model

PIF* promotes brain re-myelination locally while regulating systemic inflammation- clinically relevant multiple sclerosis M.smegmatis model

https://doi.org/10.18632/oncotarget.15662

Giuseppe Migliara, Martin Mueller, Alessia Piermattei, Chaya Brodie, Michael J. Paidas, Eytan R. Barnea,  and Francesco Ria
21834-21851
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Patterns of failure and clinical outcomes of definitive radiotherapy for cervical esophageal cancer

Patterns of failure and clinical outcomes of definitive radiotherapy for cervical esophageal cancer

https://doi.org/10.18632/oncotarget.15665

Lina Zhao, Yongchun Zhou, Yunfeng Mu, Guangjin Chai, Feng Xiao, Lina Tan, Steven H. Lin,  and Mei Shi
21852-21860
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Epigenetic inactivation of HOXA11, a novel functional tumor suppressor for renal cell carcinoma, is associated with RCC TNM classification

Epigenetic inactivation of HOXA11, a novel functional tumor suppressor for renal cell carcinoma, is associated with RCC TNM classification

https://doi.org/10.18632/oncotarget.15668

Lu Wang, Yun Cui, Jindong Sheng, Yang Yang, Guanyu Kuang, Yu Fan, Jie Jin,  and Qian Zhang
21861-21870
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Implication of vascular endothelial growth factor A and C in revealing diagnostic lymphangiogenic markers in node-positive bladder cancer

Implication of vascular endothelial growth factor A and C in revealing diagnostic lymphangiogenic markers in node-positive bladder cancer

https://doi.org/10.18632/oncotarget.15669

Cédric Poyet, Linto Thomas, Tobias M. Benoit, David Aquino Delmo, Laura Luberto, Irina Banzola, Michèle S. Günthart, Giovanni Sais, Daniel Eberli, Tullio Sulser,  and Maurizio Provenzano
21871-21883
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SPC24 is critical for anaplastic thyroid cancer progression

SPC24 is critical for anaplastic thyroid cancer progression

https://doi.org/10.18632/oncotarget.15670

Huabin Yin, Tong Meng, Lei Zhou, Haiyan Chen,  and Dianwen Song
21884-21891
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Estrogen deficiency is associated with hippocampal morphological remodeling of early postmenopausal mice

Estrogen deficiency is associated with hippocampal morphological remodeling of early postmenopausal mice

https://doi.org/10.18632/oncotarget.15702

Yan Yan, Liang Cheng, Xin Chen, Qin Wang, Mingjing Duan, Jichao Ma, Linjing Zhao, Xuemei Jiang,  and Jing Ai
21892-21902
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Overall survival with crizotinib and next-generation ALK inhibitors in ALK-positive non-small-cell lung cancer (IFCT-1302 CLINALK): a French nationwide cohort retrospective study

Overall survival with crizotinib and next-generation ALK inhibitors in ALK-positive non-small-cell lung cancer (IFCT-1302 CLINALK): a French nationwide cohort retrospective study

https://doi.org/10.18632/oncotarget.15746

Michaël Duruisseaux, Benjamin Besse, Jacques Cadranel, Maurice Pérol, Bertrand Mennecier, Laurence Bigay-Game, Renaud Descourt, Eric Dansin, Clarisse Audigier-Valette, Lionel Moreau, José Hureaux, Remi Veillon, Josiane Otto, Anne Madroszyk-Flandin, Alexis Cortot, François Guichard, Pascaline Boudou-Rouquette, Alexandra Langlais, Pascale Missy, Franck Morin,  and Denis Moro-Sibilot
21903-21917
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

JMJD3 suppresses stem cell-like characteristics in breast cancer cells by downregulation of Oct4 independently of its demethylase activity

JMJD3 suppresses stem cell-like characteristics in breast cancer cells by downregulation of Oct4 independently of its demethylase activity

https://doi.org/10.18632/oncotarget.15747

Jing Xun, Dekun Wang, Long Shen, Junbo Gong, Ruifang Gao, Lingfang Du, Antao Chang, Xiangrong Song, Rong Xiang,  and Xiaoyue Tan
21918-21929
Abstract  |  PDF  |  HTML  |  Order a Reprint

Limitations in predicting PAM50 intrinsic subtype and risk of relapse score with Ki67 in estrogen receptor-positive HER2-negative breast cancer

Limitations in predicting PAM50 intrinsic subtype and risk of relapse score with Ki67 in estrogen receptor-positive HER2-negative breast cancer

https://doi.org/10.18632/oncotarget.15748

Aranzazu Fernandez-Martinez, Tomás Pascual, Giuseppe Perrone, Serafin Morales, Juan de la Haba, Milagros González-Rivera, Patricia Galvan, Francesca Zalfa, Michaela Amato, Lucia Gonzalez, Miquel Prats, Federico Rojo, Luis Manso, Laia Paré, Immaculada Alonso, Joan Albanell, Ana Vivancos, Antonio González, Judit Matito, Sonia González, Pedro Fernandez, Barbara Adamo, Montserrat Muñoz, Margarita Viladot, Carme Font, Francisco Aya, Maria Vidal, Rosalía Caballero, Eva Carrasco, Vittorio Altomare, Giuseppe Tonini, Aleix Prat,  and Miguel Martin
21930-21937
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gene regulatory pattern analysis reveals essential role of core transcriptional factors’ activation in triple-negative breast cancer

Gene regulatory pattern analysis reveals essential role of core transcriptional factors’ activation in triple-negative breast cancer

https://doi.org/10.18632/oncotarget.15749

Li Min, Cheng Zhang, Like Qu, Jialiang Huang, Lan Jiang, Jiafei Liu, Luca Pinello, Guo-Cheng Yuan,  and Chengchao Shou
21938-21953
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Interplay between ΔNp63 and miR-138-5p regulates growth, metastasis and stemness of oral squamous cell carcinoma

Interplay between ΔNp63 and miR-138-5p regulates growth, metastasis and stemness of oral squamous cell carcinoma

https://doi.org/10.18632/oncotarget.15752

Zehang Zhuang, Nan Xie, Jing Hu, Pei Yu, Cheng Wang, Xingxue Hu, Xiaozhe Han, Jinsong Hou, Hongzhang Huang,  and Xiqiang Liu
21954-21973
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Correlations between intravoxel incoherent motion (IVIM) parameters and histological findings in rectal cancer: preliminary results

Correlations between intravoxel incoherent motion (IVIM) parameters and histological findings in rectal cancer: preliminary results

https://doi.org/10.18632/oncotarget.15753

Alexey Surov, Hans Jonas Meyer, Anne-Kathrin Höhn, Curd Behrmann, Andreas Wienke, Rolf Peter Spielmann,  and Nikita Garnov
21974-21983
Abstract  |  PDF  |  HTML  |  Order a Reprint

RNA sequencing analysis reveals protective role of kruppel-like factor 3 in colorectal cancer

RNA sequencing analysis reveals protective role of kruppel-like factor 3 in colorectal cancer

https://doi.org/10.18632/oncotarget.15766

Xiaohong Wang, Zhonghua Jiang, Yu Zhang, Xiang Wang, Li Liu,  and Zhining Fan
21984-21993
Abstract  |  PDF  |  HTML  |  Order a Reprint

DNA methylation intratumor heterogeneity in localized lung adenocarcinomas

DNA methylation intratumor heterogeneity in localized lung adenocarcinomas

https://doi.org/10.18632/oncotarget.15777

Kelly Quek, Jun Li, Marcos Estecio, Jiexin Zhang, Junya Fujimoto, Emily Roarty, Latasha Little, Chi-Wan Chow, Xingzhi Song, Carmen Behrens, Taiping Chen, William N. William, Stephen Swisher, John Heymach, Ignacio Wistuba, Jianhua Zhang, Andrew Futreal,  and Jianjun Zhang
21994-22002
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-519d impedes cisplatin-resistance in breast cancer stem cells by down-regulating the expression of MCL-1

MiR-519d impedes cisplatin-resistance in breast cancer stem cells by down-regulating the expression of MCL-1

https://doi.org/10.18632/oncotarget.15781

Qing Xie, Shuai Wang, Yue Zhao, Zhenchao Zhang, Chuan Qin,  and Xianjun Yang
22003-22013
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cell-of-origin of diffuse large B-cell lymphomas determined by the Lymph2Cx assay: better prognostic indicator than Hans algorithm

Cell-of-origin of diffuse large B-cell lymphomas determined by the Lymph2Cx assay: better prognostic indicator than Hans algorithm

https://doi.org/10.18632/oncotarget.15782

Nara Yoon, Soomin Ahn, Hae Yong Yoo, Suk Jin Kim, Won Seog Kim,  and Young Hyeh Ko
22014-22022
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hobnail variant of papillary thyroid carcinoma: molecular profiling and comparison to classical papillary thyroid carcinoma, poorly differentiated thyroid carcinoma and anaplastic thyroid carcinoma

Hobnail variant of papillary thyroid carcinoma: molecular profiling and comparison to classical papillary thyroid carcinoma, poorly differentiated thyroid carcinoma and anaplastic thyroid carcinoma

https://doi.org/10.18632/oncotarget.15786

Lianghong Teng, Wanglong Deng, Junliang Lu, Jing Zhang, Xinyu Ren, Huanli Duan, Shannon Chuai, Feidie Duan, Wei Gao, Tao Lu, Huanwen Wu,  and Zhiyong Liang
22023-22033
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tetraspanin 8 (TSPAN 8) as a potential target for radio-immunotherapy of colorectal cancer

Tetraspanin 8 (TSPAN 8) as a potential target for radio-immunotherapy of colorectal cancer

https://doi.org/10.18632/oncotarget.15787

Aurelie Maisonial-Besset, Tiffany Witkowski, Isabelle Navarro-Teulon, Odile Berthier-Vergnes, Giovanna Fois, Yingying Zhu, Sophie Besse, Olivia Bawa, Arnaud Briat, Mercedes Quintana, Alexandre Pichard, Mathilde Bonnet, Eric Rubinstein, Jean-Pierre Pouget, Paule Opolon, Lydia Maigne, Elisabeth Miot-Noirault, Jean-Michel Chezal, Claude Boucheix,  and Francoise Degoul
22034-22047
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HER2-specific recombinant immunotoxin 4D5scFv-PE40 passes through retrograde trafficking route and forces cells to enter apoptosis

HER2-specific recombinant immunotoxin 4D5scFv-PE40 passes through retrograde trafficking route and forces cells to enter apoptosis

https://doi.org/10.18632/oncotarget.15833

Evgeniya Sokolova, Evgeniy Guryev, Andrey Yudintsev, Vladimir Vodeneev, Sergey Deyev,  and Irina Balalaeva
22048-22058
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Quantitative proteomic analysis of gastric cancer tissue reveals novel proteins in platelet-derived growth factor B signaling pathway

Quantitative proteomic analysis of gastric cancer tissue reveals novel proteins in platelet-derived growth factor B signaling pathway

https://doi.org/10.18632/oncotarget.15908

Fang Liu, Yuan Zhang, Tingting Men, Xingyue Jiang, Chunhua Yang, He Li, Xiaodan Wei, Dong Yan, Gangming Feng, Jianke Yang, Jonas Bergquist, Bin Wang, Wenguo Jiang, Jia Mi,  and Geng Tian
22059-22075
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Low vitamin D status is associated with inflammation in patients with prostate cancer

Low vitamin D status is associated with inflammation in patients with prostate cancer

https://doi.org/10.18632/oncotarget.16195

Dong-Dong Xie, Yuan-Hua Chen, Shen Xu, Cheng Zhang, Da-Ming Wang, Hua Wang, Lei Chen, Zhi-Hui Zhang, Mi-Zhen Xia, De-Xiang Xu,  and De-Xin Yu
22076-22085
Abstract  |  PDF  |  HTML  |  Order a Reprint

Karyotyping and analysis of GNAS locus in intramuscular myxomas

Karyotyping and analysis of GNAS locus in intramuscular myxomas

https://doi.org/10.18632/oncotarget.14986

Ioannis Panagopoulos, Ludmila Gorunova, Ingvild Lobmaier, Bodil Bjerkehagen,  and Sverre Heim
22086-22094
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Clinical Research Papers

Development and comparison of a Chinese nomogram adding multi-parametric MRI information for predicting extracapsular extension of prostate cancer

Development and comparison of a Chinese nomogram adding multi-parametric MRI information for predicting extracapsular extension of prostate cancer

https://doi.org/10.18632/oncotarget.11559

Yuke Chen, Wei Yu, Yu Fan, Liqun Zhou, Yang Yang, Huihui Wang, Yuan Jiang, Xiaoying Wang, Shiliang Wu,  and Jie Jin
22095-22103
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A phase I-II trial of fludarabine, bendamustine and rituximab (FBR) in previously treated patients with CLL

A phase I-II trial of fludarabine, bendamustine and rituximab (FBR) in previously treated patients with CLL

https://doi.org/10.18632/oncotarget.12054

Nitin Jain, Kumudha Balakrishnan, Alessandra Ferrajoli, Susan M. O’Brien, Jan A. Burger, Tapan M. Kadia, Jorge E. Cortes, Mary L. Ayres, Francesco Paolo Tambaro, Michael J. Keating, Varsha Gandhi,  and William G. Wierda
22104-22112
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Crossing the perspectives of patients, families, and physicians on cancer treatment: A qualitative study

Crossing the perspectives of patients, families, and physicians on cancer treatment: A qualitative study

https://doi.org/10.18632/oncotarget.12770

Massimiliano Orri, Jordan Sibeoni, Guilhem Bousquet, Mathilde Labey, Juliette Gueguen, Cyril Laporte, Sabine Winterman, Camille Picard, Clara Nascimbeni, Laurence Verneuil,  and Anne Revah-Levy
22113-22122
Abstract  |  PDF  |  HTML  |  Order a Reprint

Neuroendocrine tumors of colon and rectum: validation of clinical and prognostic values of the World Health Organization 2010 grading classifications and European Neuroendocrine Tumor Society staging systems

Neuroendocrine tumors of colon and rectum: validation of clinical and prognostic values of the World Health Organization 2010 grading classifications and European Neuroendocrine Tumor Society staging systems

https://doi.org/10.18632/oncotarget.13641

Chaoyong Shen, Yuan Yin, Huijiao Chen, Sumin Tang, Xiaonan Yin, Zongguang Zhou, Bo Zhang,  and Zhixin Chen
22123-22134
Abstract  |  PDF  |  HTML  |  Order a Reprint

A multicenter phase II study of salvage photodynamic therapy using talaporfin sodium (ME2906) and a diode laser (PNL6405EPG) for local failure after chemoradiotherapy or radiotherapy for esophageal cancer

A multicenter phase II study of salvage photodynamic therapy using talaporfin sodium (ME2906) and a diode laser (PNL6405EPG) for local failure after chemoradiotherapy or radiotherapy for esophageal cancer

https://doi.org/10.18632/oncotarget.14029

Tomonori Yano, Hiroi Kasai, Takahiro Horimatsu, Kenichi Yoshimura, Satoshi Teramukai, Satoshi Morita, Harue Tada, Yoshinobu Yamamoto, Hiromi Kataoka, Naomi Kakushima, Ryu Ishihara, Hajime Isomoto,  and Manabu Muto
22135-22144
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

Involvement of inflammation and its related microRNAs in hepatocellular carcinoma

Involvement of inflammation and its related microRNAs in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.13530

Ke Jin, Tong Li, Gonzalo Sánchez-Duffhues, Fangfang Zhou,  and Long Zhang
22145-22165
Abstract  |  PDF  |  HTML  |  Order a Reprint

An early biomarker and potential therapeutic target of RUNX 3 hypermethylation in breast cancer, a system review and meta-analysis

An early biomarker and potential therapeutic target of RUNX 3 hypermethylation in breast cancer, a system review and meta-analysis

https://doi.org/10.18632/oncotarget.13125

De-guo Lu, Ying-mei Ma, Ai-ju Zhu,  and Yun-wei Han
22166-22174
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

KRAS and TP53 mutations in inflammatory bowel disease-associated colorectal cancer: a meta-analysis

KRAS and TP53 mutations in inflammatory bowel disease-associated colorectal cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.14549

Lijun Du, John J. Kim, Jinhua Shen, Binrui Chen,  and Ning Dai
22175-22186
Abstract  |  PDF  |  HTML  |  Order a Reprint

Long non-coding RNAs: a rising biotarget in colorectal cancer

Long non-coding RNAs: a rising biotarget in colorectal cancer

https://doi.org/10.18632/oncotarget.14728

Jian Luo, Jian Qu, Dong-Kai Wu, Zhi-Li Lu, Yue-Sheng Sun,  and Qiang Qu
22187-22202
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dysregulations in the PI3K pathway and targeted therapies for head and neck squamous cell carcinoma

Dysregulations in the PI3K pathway and targeted therapies for head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.14729

Yi Cai, Sonam Dodhia,  and Gloria H. Su
22203-22217
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeting oncogenic vulnerabilities in triple negative breast cancer: biological bases and ongoing clinical studies

Targeting oncogenic vulnerabilities in triple negative breast cancer: biological bases and ongoing clinical studies

https://doi.org/10.18632/oncotarget.14731

Alberto Ocana,  and Atanasio Pandiella
22218-22234
Abstract  |  PDF  |  HTML  |  Order a Reprint

RNA binding motif protein 3: a potential biomarker in cancer and therapeutic target in neuroprotection

RNA binding motif protein 3: a potential biomarker in cancer and therapeutic target in neuroprotection

https://doi.org/10.18632/oncotarget.14755

Ren-Bin Zhou, Xiao-Li Lu, Chen-Yan Zhang,  and Da-Chuan Yin
22235-22250
Abstract  |  PDF  |  HTML  |  Order a Reprint

Consolidative thoracic radiotherapy for extensive stage small cell lung cancer

Consolidative thoracic radiotherapy for extensive stage small cell lung cancer

https://doi.org/10.18632/oncotarget.14759

Xiaoli Zhang, Jinming Yu, Hui Zhu, Xue Meng, Minghuan Li, Liyang Jiang, Xingchen Ding,  and Xindong Sun
22251-22261
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNAs in melanoma development and resistance to target therapy

MicroRNAs in melanoma development and resistance to target therapy

https://doi.org/10.18632/oncotarget.14763

Luigi Fattore, Susan Costantini, Debora Malpicci, Ciro Francesco Ruggiero, Paolo Antonio Ascierto, Carlo M. Croce, Rita Mancini,  and Gennaro Ciliberto
22262-22278
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metabotropic glutamate receptors as a new therapeutic target for malignant gliomas

Metabotropic glutamate receptors as a new therapeutic target for malignant gliomas

https://doi.org/10.18632/oncotarget.15299

Mery Stefani Leivas Pereira, Fábio Klamt, Chairini Cássia Thomé, Paulo Valdeci Worm,  and Diogo Losch de Oliveira
22279-22298
Abstract  |  PDF  |  HTML  |  Order a Reprint

Case Reports

Membranous nephropathy associated with hepatitis C virus infection treated with corticosteroids and Ledipasvir-Sofosbuvir: a case report and review of literature

Membranous nephropathy associated with hepatitis C virus infection treated with corticosteroids and Ledipasvir-Sofosbuvir: a case report and review of literature

https://doi.org/10.18632/oncotarget.15397

Qinjie Weng, Xiao Li, Hong Ren, Jingyuan Xie, Xiaoxia Pan, Jing Xu,  and Nan Chen
22299-22303
Abstract  |  PDF  |  HTML  |  Order a Reprint

Corrections

Correction: Protective role of p53 in skin cancer: Carcinogenesis studies in mice lacking epidermal p53

Correction: Protective role of p53 in skin cancer: Carcinogenesis studies in mice lacking epidermal p53

https://doi.org/10.18632/oncotarget.16592

Angustias Page, Manuel Navarro, Cristian Suarez-Cabrera, Josefa P. Alameda, M. Llanos Casanova, Jesús M. Paramio, Ana Bravo,  and Angel Ramirez
22304-22304
Correction  |  PDF


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