Oncotarget

Vol 8, No 10

March 7, 2017

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About The Cover

The cover for issue 10 of Oncotarget features "Regulatory network of 9 novel AD biomarker candidate miRNAs and their putative cellular effectors," from Nagaraj, et al.

Table of Contents

News

Androgen receptor variants: another twist in the plot

Androgen receptor variants: another twist in the plot

https://doi.org/10.18632/oncotarget.15130

Jill A. Macoska
16100-16100
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Editorial

TRPV1 in pain control from the brain

TRPV1 in pain control from the brain

https://doi.org/10.18632/oncotarget.13316

Daniel Martins, Marta Silva,  and Isaura Tavares
16101-16102
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Editorial: Neuroscience

Targeting OSMR in glioma stem cells

Targeting OSMR in glioma stem cells

https://doi.org/10.18632/oncotarget.15066

Sushmetha Mohan, Azad Bonni,  and Arezu Jahani-Asl
16103-16104
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Bingeing on fat increases cocaine reward

Bingeing on fat increases cocaine reward

https://doi.org/10.18632/oncotarget.15260

M. Carmen Blanco-Gandía,  and Marta Rodríguez-Arias
16105-16106
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Brain histamine and behavioral neuroscience

Brain histamine and behavioral neuroscience

https://doi.org/10.18632/oncotarget.15365

Andrea Santangelo, Maria Beatrice Passani,  and Maurizio Casarrubea
16107-16108
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Research Papers: Gerotarget (Focus on Aging)

Alleviation of senescence and epithelial-mesenchymal transition in aging kidney by short-term caloric restriction and caloric restriction mimetics via modulation of AMPK/mTOR signaling

Alleviation of senescence and epithelial-mesenchymal transition in aging kidney by short-term caloric restriction and caloric restriction mimetics via modulation of AMPK/mTOR signaling

https://doi.org/10.18632/oncotarget.14884

Dan Dong, Guang-yan Cai, Yi-chun Ning, Jing-chao Wang, Yang Lv, Quan Hong, Shao-yuan Cui, Bo Fu, Ya-nan Guo,  and Xiang-mei Chen
16109-16121
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Profile of 6 microRNA in blood plasma distinguish early stage Alzheimer’s disease patients from non-demented subjects

Profile of 6 microRNA in blood plasma distinguish early stage Alzheimer’s disease patients from non-demented subjects

https://doi.org/10.18632/oncotarget.15109

Siranjeevi Nagaraj, Katarzyna Laskowska-Kaszub, Konrad J. Dębski, Joanna Wojsiat, Michał Dąbrowski, Tomasz Gabryelewicz, Jacek Kuźnicki,  and Urszula Wojda
16122-16143
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Research Papers: Pathology

Identification of novel biomarkers for prediction of neurological prognosis following cardiac arrest

Identification of novel biomarkers for prediction of neurological prognosis following cardiac arrest

https://doi.org/10.18632/oncotarget.14877

Jung Woo Eun, Hee Doo Yang, Soo Hyun Kim, Sungyoup Hong, Kyu Nam Park, Suk Woo Nam,  and Sikyoung Jeong
16144-16157
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Protective effect of DHEA on hydrogen peroxide-induced oxidative damage and apoptosis in primary rat Leydig cells

Protective effect of DHEA on hydrogen peroxide-induced oxidative damage and apoptosis in primary rat Leydig cells

https://doi.org/10.18632/oncotarget.15300

Xiao Ding, Lei Yu, Lei Yu, Chongyang Ge, Chongyang Ge, Haitian Ma,  and Haitian Ma
16158-16169
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Research Papers: Autophagy and Cell Death

Sub-lethal oxidative stress induces lysosome biogenesis via a lysosomal membrane permeabilization-cathepsin-caspase 3-transcription factor EB-dependent pathway

Sub-lethal oxidative stress induces lysosome biogenesis via a lysosomal membrane permeabilization-cathepsin-caspase 3-transcription factor EB-dependent pathway

https://doi.org/10.18632/oncotarget.14016

San Min Leow, Shu Xian Serene Chua, Gireedhar Venkatachalam, Liang Shen, Le Luo,  and Marie-Veronique Clement
16170-16189
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Research Papers

XPD c.934G>A polymorphism of nucleotide excision repair pathway in outcome of head and neck squamous cell carcinoma patients treated with cisplatin chemoradiation

XPD c.934G>A polymorphism of nucleotide excision repair pathway in outcome of head and neck squamous cell carcinoma patients treated with cisplatin chemoradiation

https://doi.org/10.18632/oncotarget.7668

Leisa Lopes-Aguiar, Ericka Francislaine Dias Costa, Guilherme Augusto Silva Nogueira, Tathiane Regine Penna Lima, Marília Berlofa Visacri, Eder Carvalho Pincinato, Luciane Calonga, Fernanda Viviane Mariano, Albina Messias de Almeida Milani Altemani, João Maurício Carrasco Altemani, Cláudia Malheiros Coutinho-Camillo, Maria Almerinda Vieira Fernandes Ribeiro Alves, Patrícia Moriel, Celso Dario Ramos, Carlos Takahiro Chone,  and Carmen Silvia Passos Lima
16190-16201
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p63 drives invasion in keratinocytes expressing HPV16 E6/E7 genes through regulation of Src-FAK signalling

p63 drives invasion in keratinocytes expressing HPV16 E6/E7 genes through regulation of Src-FAK signalling

https://doi.org/10.18632/oncotarget.3892

Kirtiman Srivastava, Adam Pickard, Simon McDade,  and Dennis J. McCance
16202-16219
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Complementary dynamic BH3 profiles predict co-operativity between the multi-kinase inhibitor TG02 and the BH3 mimetic ABT-199 in acute myeloid leukaemia cells

Complementary dynamic BH3 profiles predict co-operativity between the multi-kinase inhibitor TG02 and the BH3 mimetic ABT-199 in acute myeloid leukaemia cells

https://doi.org/10.18632/oncotarget.8742

Monica Pallis, Francis Burrows, Jeremy Ryan, Martin Grundy, Claire Seedhouse, Amina Abdul-Aziz, Joan Montero, Anthony Letai,  and Nigel Russell
16220-16232
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IKKε and TBK1 expression in gastric cancer

IKKε and TBK1 expression in gastric cancer

https://doi.org/10.18632/oncotarget.9069

Seung Eun Lee, Mineui Hong, Junhun Cho, Jeeyun Lee,  and Kyoung-Mee Kim
16233-16242
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Primary mediastinal large B-cell lymphoma: transcriptional regulation by miR-92a through FOXP1 targeting

Primary mediastinal large B-cell lymphoma: transcriptional regulation by miR-92a through FOXP1 targeting

https://doi.org/10.18632/oncotarget.12988

Martha Romero, Guillaume Gapihan, Luis Jaime Castro-Vega, Andrés Acevedo, Li Wang, Zhao Wei Li, Morad El Bouchtaoui, Mélanie Di Benedetto, Philippe Ratajczak, Jean-Paul Feugeas, Catherine Thieblemont, Carlos Saavedra,  and Anne Janin
16243-16258
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Idelalisib and bendamustine combination is synergistic and increases DNA damage response in chronic lymphocytic leukemia cells

Idelalisib and bendamustine combination is synergistic and increases DNA damage response in chronic lymphocytic leukemia cells

https://doi.org/10.18632/oncotarget.15180

Prexy Modi, Kumudha Balakrishnan, Qingshan Yang, William G. Wierda, Michael J. Keating,  and Varsha Gandhi
16259-16274
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In vivo histone H1 migration from necrotic to viable tissue

In vivo histone H1 migration from necrotic to viable tissue

https://doi.org/10.18632/oncotarget.15181

Keith A. Luhrs, Desmond Pink, Wendy Schulte, Andries Zijlstra, John D. Lewis,  and Missag H. Parseghian
16275-16292
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GLTSCR2 promotes the nucleoplasmic translocation and subsequent degradation of nucleolar ARF

GLTSCR2 promotes the nucleoplasmic translocation and subsequent degradation of nucleolar ARF

https://doi.org/10.18632/oncotarget.9957

Sun Lee, Young-Eun Cho, Sang-Hoon Kim, Yong-Jun Kim,  and Jae-Hoon Park
16293-16302
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Sensitizing thermochemotherapy with a PARP1-inhibitor

Sensitizing thermochemotherapy with a PARP1-inhibitor

https://doi.org/10.18632/oncotarget.11422

Arlene L. Oei, Lianne E.M. Vriend, Caspar M. van Leeuwen, Hans M. Rodermond, Rosemarie ten Cate, Anneke M. Westermann, Lukas J.A. Stalpers, Johannes Crezee, Roland Kanaar, H. Petra Kok, Przemek M. Krawczyk,  and Nicolaas A.P. Franken
16303-16312
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Variations within 3'-UTR of MDM4 gene contribute to clinical outcomes of advanced non-small cell lung cancer patients following platinum-based chemotherapy

Variations within 3'-UTR of MDM4 gene contribute to clinical outcomes of advanced non-small cell lung cancer patients following platinum-based chemotherapy

https://doi.org/10.18632/oncotarget.10771

Yang Yang, Wen Gao, Xi Ding, Wen Xu, Di Liu, Bo Su,  and Yifeng Sun
16313-16324
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Characterization and phylogenetic analysis of Krüppel-like transcription factor (KLF) gene family in tree shrews (Tupaia belangeri chinensis)

Characterization and phylogenetic analysis of Krüppel-like transcription factor (KLF) gene family in tree shrews (Tupaia belangeri chinensis)

https://doi.org/10.18632/oncotarget.13883

Ming Shao, Guang-Zhe Ge, Wen-Jing Liu, Ji Xiao, Hou-Jun Xia, Yu Fan, Feng Zhao, Bao-Li He,  and Ceshi Chen
16325-16339
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The embryonic type of SPP1 transcriptional regulation is re-activated in glioblastoma

The embryonic type of SPP1 transcriptional regulation is re-activated in glioblastoma

https://doi.org/10.18632/oncotarget.14092

Magdalena Kijewska, Marta Kocyk, Michal Kloss, Karolina Stepniak, Zbigniew Korwek, Renata Polakowska, Michal Dabrowski, Anna Gieryng, Bartosz Wojtas, Iwona A. Ciechomska,  and Bozena Kaminska
16340-16355
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Stiehopus japonieus acidic mucopolysaccharide inhibits the proliferation of pancreatic cancer SW1990 cells through Hippo-YAP pathway

Stiehopus japonieus acidic mucopolysaccharide inhibits the proliferation of pancreatic cancer SW1990 cells through Hippo-YAP pathway

https://doi.org/10.18632/oncotarget.14633

Xiaoyu Li, Yi Liu, Cuiping Zhang, Qinghui Niu, Hui Wang, Cong Che, Man Xie, Bin Zhou, Yonghong Xu, Qi Zhang, Jun Wu,  and Zibin Tian
16356-16366
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The HDAC inhibitor AR42 interacts with pazopanib to kill trametinib/dabrafenib-resistant melanoma cells in vitro and in vivo

The HDAC inhibitor AR42 interacts with pazopanib to kill trametinib/dabrafenib-resistant melanoma cells in vitro and in vivo

https://doi.org/10.18632/oncotarget.14829

Laurence Booth, Jane L. Roberts, Cindy Sander, John Lee, John M. Kirkwood, Andrew Poklepovic,  and Paul Dent
16367-16386
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RNPC1 enhances progesterone receptor functions by regulating its mRNA stability in breast cancer

RNPC1 enhances progesterone receptor functions by regulating its mRNA stability in breast cancer

https://doi.org/10.18632/oncotarget.12016

Peipei Lou, Chunlian Li, Liang Shi, Tian-Song Xia, Wenbin Zhou, Jing Wu, Xujie Zhou, Xiaoxia Li, Ying Wang, Ji-Fu Wei,  and Qiang Ding
16387-16400
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hypoxia reduces testosterone synthesis in mouse Leydig cells by inhibiting NRF1-activated StAR expression

Hypoxia reduces testosterone synthesis in mouse Leydig cells by inhibiting NRF1-activated StAR expression

https://doi.org/10.18632/oncotarget.14842

Xueting Wang, Longlu Pan, Zhiran Zou, Dan Wang, Yapeng Lu, Zhangji Dong,  and Li Zhu
16401-16413
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The complicated role of venous drainage on the survival of arterialized venous flaps

The complicated role of venous drainage on the survival of arterialized venous flaps

https://doi.org/10.18632/oncotarget.14845

Weidong Weng, Feng Zhang, Bin Zhao, Zhipeng Wu, Weiyang Gao, Zhijie Li,  and Hede Yan
16414-16420
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The significance of programmed cell death ligand 1 expression in resected lung adenocarcinoma

The significance of programmed cell death ligand 1 expression in resected lung adenocarcinoma

https://doi.org/10.18632/oncotarget.14851

Shafei Wu, Xiaohua Shi, Jian Sun, Yuanyuan Liu, Yufeng Luo, Zhiyong Liang, Jinghui Wang,  and Xuan Zeng
16421-16429
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The antiangiogenic role of the pro-inflammatory cytokine interleukin-31

The antiangiogenic role of the pro-inflammatory cytokine interleukin-31

https://doi.org/10.18632/oncotarget.14857

Shiri Davidi, Ella Fremder, Tal Kan, Ziv Raviv, Michael Timaner, Nathan Karin, Dov Hershkovitz, Ami Arohneim,  and Yuval Shaked
16430-16444
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Prognostic value of reduced E-cadherin expression in breast cancer: a meta-analysis

Prognostic value of reduced E-cadherin expression in breast cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.14860

Zhan Li, Songcheng Yin, Lei Zhang, Weiguang Liu,  and Bo Chen
16445-16455
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Generation of in vivo neural stem cells using partially reprogrammed cells defective in in vitro differentiation potential

Generation of in vivo neural stem cells using partially reprogrammed cells defective in in vitro differentiation potential

https://doi.org/10.18632/oncotarget.14861

Jong Soo Kim, Yean Ju Hong, Hyun Woo Choi, Hyuk Song, Sung June Byun,  and Jeong Tae Do
16456-16462
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of novel follicular dendritic cell sarcoma markers, FDCSP and SRGN, by whole transcriptome sequencing

Identification of novel follicular dendritic cell sarcoma markers, FDCSP and SRGN, by whole transcriptome sequencing

https://doi.org/10.18632/oncotarget.14864

Luisa Lorenzi, Claudia Döring, Tobias Rausch, Vladimir Benes, Silvia Lonardi, Mattia Bugatti, Elias Campo, José Cabeçadas, Ingrid Simonitsch-Klupp, Anita Borges, Jay Mehta, Claudio Agostinelli, Stefano Aldo Pileri, Fabio Facchetti, Martin-Leo Hansmann,  and Sylvia Hartmann
16463-16472
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Loss of MTSS1 results in increased metastatic potential in pancreatic cancer

Loss of MTSS1 results in increased metastatic potential in pancreatic cancer

https://doi.org/10.18632/oncotarget.14869

Ann E. Zeleniak, Wei Huang, Mary K. Brinkman, Melissa L. Fishel,  and Reginald Hill
16473-16487
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association of VEGFA polymorphisms with susceptibility and clinical outcome of hepatocellular carcinoma in a Chinese Han population

Association of VEGFA polymorphisms with susceptibility and clinical outcome of hepatocellular carcinoma in a Chinese Han population

https://doi.org/10.18632/oncotarget.14870

Fei Liu, Limei Luo, Yonggang Wei, Wentao Wang, Tianfu Wen, Jiayin Yang, Mingqing Xu,  and Bo Li
16488-16497
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Serum Golgi protein 73 is not a suitable diagnostic marker for hepatocellular carcinoma

Serum Golgi protein 73 is not a suitable diagnostic marker for hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.14954

Tianhui Liu, Mingjie Yao, Shuhong Liu, Lu Wang, Leijie Wang, Jinlin Hou, Xiong Ma, Jidong Jia, Jingmin Zhao, Hui Zhuang,  and Fengmin Lu
16498-16506
Abstract  |  PDF  |  HTML  |  Order a Reprint

The level of epidermal growth factor receptors expression is correlated with the advancement of colorectal adenoma: validation of a surface biomarker

The level of epidermal growth factor receptors expression is correlated with the advancement of colorectal adenoma: validation of a surface biomarker

https://doi.org/10.18632/oncotarget.14961

Nicolas Williet, Carmen Adina Petcu, Leslie Rinaldi, Michèle Cottier, Emilie Del Tedesco, Léa Clavel, Olivier Dumas, Camille Jarlot, Nadia Bouarioua, Xavier Roblin, Michel Peoc’h,  and Jean-Marc Phelip
16507-16517
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Near infrared fluorescent imaging of choline kinase alpha expression and inhibition in breast tumors

Near infrared fluorescent imaging of choline kinase alpha expression and inhibition in breast tumors

https://doi.org/10.18632/oncotarget.14965

Sean P. Arlauckas, Manoj Kumar, Anatoliy V. Popov, Harish Poptani,  and Edward J. Delikatny
16518-16530
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical significance and effect of AEG-1 on the proliferation, invasion, and migration of NSCLC: a study based on immunohistochemistry, TCGA, bioinformatics, in vitro and in vivo verification

Clinical significance and effect of AEG-1 on the proliferation, invasion, and migration of NSCLC: a study based on immunohistochemistry, TCGA, bioinformatics, in vitro and in vivo verification

https://doi.org/10.18632/oncotarget.14972

Yu Zhang, Zu-Yun Li, Xin-Xi Hou, Xiao Wang, Yi-Huan Luo, Yan-Ping Ying,  and Gang Chen
16531-16552
Abstract  |  PDF  |  HTML  |  Order a Reprint

Generation and characteristics of human Sertoli cell line immortalized by overexpression of human telomerase

Generation and characteristics of human Sertoli cell line immortalized by overexpression of human telomerase

https://doi.org/10.18632/oncotarget.14985

Liping Wen, Qingqing Yuan, Min Sun, Minghui Niu, Hong Wang, Hongyong Fu, Fan Zhou, Chencheng Yao, Xiaobo Wang, Zheng Li,  and Zuping He
16553-16570
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The subclonal structure and genomic evolution of oral squamous cell carcinoma revealed by ultra-deep sequencing

The subclonal structure and genomic evolution of oral squamous cell carcinoma revealed by ultra-deep sequencing

https://doi.org/10.18632/oncotarget.15014

Siavosh Tabatabaeifar, Mads Thomassen, Martin J. Larsen, Stine R. Larsen, Torben A. Kruse,  and Jens A. Sørensen
16571-16580
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The role of miR-24 as a race related genetic factor in prostate cancer

The role of miR-24 as a race related genetic factor in prostate cancer

https://doi.org/10.18632/oncotarget.15016

Yutaka Hashimoto, Marisa Shiina, Taku Kato, Soichiro Yamamura, Yuichiro Tanaka, Shahana Majid, Sharanjot Saini, Varahram Shahryari, Priyanka Kulkarni, Pritha Desgupta, Yozo Mitsui, Mitsuho Sumida, Guoren Deng, Laura Tabatabai, Deepak Kumar,  and Rajvir Dahiya
16581-16593
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comparative transcriptomic analysis of mice liver treated with different AMPK activators in a mice model of atherosclerosis

Comparative transcriptomic analysis of mice liver treated with different AMPK activators in a mice model of atherosclerosis

https://doi.org/10.18632/oncotarget.15027

Ang Ma, Dongmei Wang, Yuanyuan An, Wei Fang,  and Haibo Zhu
16594-16604
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Anti-GD2-ch14.18/CHO coated nanoparticles mediate glioblastoma (GBM)-specific delivery of the aromatase inhibitor, Letrozole, reducing proliferation, migration and chemoresistance in patient-derived GBM tumor cells

Anti-GD2-ch14.18/CHO coated nanoparticles mediate glioblastoma (GBM)-specific delivery of the aromatase inhibitor, Letrozole, reducing proliferation, migration and chemoresistance in patient-derived GBM tumor cells

https://doi.org/10.18632/oncotarget.15073

Amanda Tivnan, Tatjana Heilinger, Joanne M. Ramsey, Gemma O'Connor, Jenny L. Pokorny, Jann N. Sarkaria, Brett W. Stringer, Bryan W. Day, Andrew W. Boyd, Ella L. Kim, Holger N. Lode, Sally-Ann Cryan,  and Jochen H.M. Prehn
16605-16620
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression long non-coding RNA LINC00673 is associated with poor prognosis and promotes invasion and metastasis in tongue squamous cell carcinoma

Overexpression long non-coding RNA LINC00673 is associated with poor prognosis and promotes invasion and metastasis in tongue squamous cell carcinoma

https://doi.org/10.18632/oncotarget.14200

Jianjun Yu, Yan Liu, Zhaojian Gong, Shanshan Zhang, Can Guo, Xiayu Li, Yanyan Tang, Liting Yang, Yi He, Fang Wei, Yumin Wang, Qianjin Liao, Wenling Zhang, Xiaoling Li, Yong Li, Guiyuan Li, Wei Xiong,  and Zhaoyang Zeng
16621-16632
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

microRNA-375 inhibits colorectal cancer cells proliferation by downregulating JAK2/STAT3 and MAP3K8/ERK signaling pathways

microRNA-375 inhibits colorectal cancer cells proliferation by downregulating JAK2/STAT3 and MAP3K8/ERK signaling pathways

https://doi.org/10.18632/oncotarget.15114

Ran Wei, Qin Yang, Bing Han, Yan Li, Kun Yao, Xiuyu Yang, Zexi Chen, Shanshan Yang, Jiaqi Zhou, Meizhang Li, Haijing Yu, Min Yu,  and Qinghua Cui
16633-16641
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cell-free DNA detected by “liquid biopsy” as a potential prognostic biomarker in early breast cancer

Cell-free DNA detected by “liquid biopsy” as a potential prognostic biomarker in early breast cancer

https://doi.org/10.18632/oncotarget.15120

Roberta Maltoni, Valentina Casadio, Sara Ravaioli, Flavia Foca, Maria Maddalena Tumedei, Samanta Salvi, Filippo Martignano, Daniele Calistri, Andrea Rocca, Alessio Schirone, Dino Amadori,  and Sara Bravaccini
16642-16649
Abstract  |  PDF  |  HTML  |  Order a Reprint

Elucidation of the genetic and epigenetic landscape alterations in RNA binding proteins in glioblastoma

Elucidation of the genetic and epigenetic landscape alterations in RNA binding proteins in glioblastoma

https://doi.org/10.18632/oncotarget.14287

Shruti Bhargava, Vikas Patil, Kulandaivelu Mahalingam,  and Kumaravel Somasundaram
16650-16668
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Heterogeneity in sarcoma cell lines reveals enhanced motility of tetraploid versus diploid cells

Heterogeneity in sarcoma cell lines reveals enhanced motility of tetraploid versus diploid cells

https://doi.org/10.18632/oncotarget.14291

Mohamed Jemaà, Samer Abdallah, Gwendaline Lledo, Gaelle Perot, Tom Lesluyes, Catherine Teyssier, Pierre Roux, Juliette van Dijk, Frederic Chibon, Ariane Abrieu,  and Nathalie Morin
16669-16689
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel integrative risk index of papillary thyroid cancer progression combining genomic alterations and clinical factors

A novel integrative risk index of papillary thyroid cancer progression combining genomic alterations and clinical factors

https://doi.org/10.18632/oncotarget.15128

Qing Cheng, Xuechan Li, Chaitanya R. Acharya, Terry Hyslop,  and Julie Ann Sosa
16690-16703
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinicopathological significance of SMAD4 loss in pancreatic ductal adenocarcinomas: a systematic review and meta-analysis

Clinicopathological significance of SMAD4 loss in pancreatic ductal adenocarcinomas: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.14335

Jin-Dao Wang, Ketao Jin, Xiao-Ying Chen, Jie-Qing Lv,  and Ke-Wei Ji
16704-16711
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SMYD2 lysine methyltransferase regulates leukemia cell growth and regeneration after genotoxic stress

SMYD2 lysine methyltransferase regulates leukemia cell growth and regeneration after genotoxic stress

https://doi.org/10.18632/oncotarget.15147

Adi Zipin-Roitman, Nasma Aqaqe, Muhammad Yassin, Shahar Biechonski, Mariam Amer, Mark F. van Delft, Olga I. Gan, Sean P. McDermott, Alla Buzina, Troy Ketela, Liran Shlush, Stephanie Xie, Veronique Voisin, Jason Moffat, Mark D. Minden, John E. Dick,  and Michael Milyavsky
16712-16727
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A screen for Fli-1 transcriptional modulators identifies PKC agonists that induce erythroid to megakaryocytic differentiation and suppress leukemogenesis

A screen for Fli-1 transcriptional modulators identifies PKC agonists that induce erythroid to megakaryocytic differentiation and suppress leukemogenesis

https://doi.org/10.18632/oncotarget.14377

Tangjingjun Liu, Yao Yao, Gang Zhang, Ye Wang, Bin Deng, Jialei Song, Xiaogang Li, Fei Han, Xiao Xiao, Jue Yang, Lei Xia, You-Jun Li, Maksym Plachynta, Mu Zhang, Chen Yan, Shuzhen Mu, Heng Luo, Eldad Zacksenhaus, Xiaojiang Hao,  and Yaacov Ben-David
16728-16743
Abstract  |  PDF  |  HTML  |  Order a Reprint

HIPK2-T566 autophosphorylation diversely contributes to UV- and doxorubicin-induced HIPK2 activation

HIPK2-T566 autophosphorylation diversely contributes to UV- and doxorubicin-induced HIPK2 activation

https://doi.org/10.18632/oncotarget.14421

Alessandra Verdina, Giuliana Di Rocco, Ilaria Virdia, Laura Monteonofrio, Veronica Gatti, Eleonora Policicchio, Alessandro Bruselles, Marco Tartaglia,  and Silvia Soddu
16744-16754
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic significance of neutrophil-to-lymphocyte ratio in cervical cancer: A systematic review and meta-analysis of observational studies

Prognostic significance of neutrophil-to-lymphocyte ratio in cervical cancer: A systematic review and meta-analysis of observational studies

https://doi.org/10.18632/oncotarget.15157

Qi-Tao Huang, Qian-Qian Man, Jia Hu, Yi-lin Yang, Yue-Mei Zhang, Wei Wang, Mei Zhong,  and Yan-Hong Yu
16755-16764
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Genetic variants in the TGFβ-signaling pathway influence expression of miRNAs in colon and rectal normal mucosa and tumor tissue

Genetic variants in the TGFβ-signaling pathway influence expression of miRNAs in colon and rectal normal mucosa and tumor tissue

https://doi.org/10.18632/oncotarget.14508

Martha L. Slattery, Andromahi Trivellas, Andrew J. Pellatt, Lila E. Mullany, John R. Stevens, Roger K. Wolff,  and Jennifer S. Herrick
16765-16783
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XIAP 3'-untranslated region as a ceRNA promotes FSCN1 function in inducing the progression of breast cancer by binding endogenous miR-29a-5p

XIAP 3'-untranslated region as a ceRNA promotes FSCN1 function in inducing the progression of breast cancer by binding endogenous miR-29a-5p

https://doi.org/10.18632/oncotarget.15159

Qiang Wu, Hong Yan, Si-Qi Tao, Xiao-Nan Wang, Lang Mou, Ping Chen, Xing-Wang Cheng, Wen-Yong Wu,  and Zheng-Sheng Wu
16784-16800
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Recombinant adeno-associated virus expressing a p53-derived apoptotic peptide (37AA) inhibits HCC cells growth in vitro and in vivo

Recombinant adeno-associated virus expressing a p53-derived apoptotic peptide (37AA) inhibits HCC cells growth in vitro and in vivo

https://doi.org/10.18632/oncotarget.15160

Hongyong Zhang, Yufeng Wang, Yanxia Bai, Yuan Shao, Jigang Bai, Zhenhua Ma, Qingguang Liu,  and Shengli Wu
16801-16810
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Comprehensive investigation of a novel differentially expressed lncRNA expression profile signature to assess the survival of patients with colorectal adenocarcinoma

Comprehensive investigation of a novel differentially expressed lncRNA expression profile signature to assess the survival of patients with colorectal adenocarcinoma

https://doi.org/10.18632/oncotarget.15161

Jiang-Hui Zeng, Liang Liang, Rong-Quan He, Rui-Xue Tang, Xiao-Yong Cai, Jun-Qiang Chen, Dian-Zhong Luo,  and Gang Chen
16811-16828
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Doxycycline directly targets PAR1 to suppress tumor progression

Doxycycline directly targets PAR1 to suppress tumor progression

https://doi.org/10.18632/oncotarget.15166

Weilong Zhong, Shuang Chen, Qiang Zhang, Ting Xiao, Yuan Qin, Ju Gu, Bo Sun, Yanrong Liu, Xiangyan Jing, Xuejiao Hu, Peng Zhang, Honggang Zhou, Tao Sun,  and Cheng Yang
16829-16842
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Recurrent fusion transcripts in squamous cell carcinomas of the vulva

Recurrent fusion transcripts in squamous cell carcinomas of the vulva

https://doi.org/10.18632/oncotarget.15167

Marta Brunetti, Antonio Agostini, Ben Davidson, Claes G Tropé, Sverre Heim, Ioannis Panagopoulos,  and Francesca Micci
16843-16850
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Interface between breast cancer cells and the tumor microenvironment using platelet-rich plasma to promote tumor angiogenesis - influence of platelets and fibrin bundles on the behavior of breast tumor cells

Interface between breast cancer cells and the tumor microenvironment using platelet-rich plasma to promote tumor angiogenesis - influence of platelets and fibrin bundles on the behavior of breast tumor cells

https://doi.org/10.18632/oncotarget.15170

Sheila Siqueira Andrade, Joana Tomomi Sumikawa, Eloísa Dognani Castro, Fabricio Pereira Batista, Edgar Paredes-Gamero, Lilian Carolina Oliveira, Izabel Monastério Guerra, Giovani Bravin Peres, Renan Pelluzzi Cavalheiro, Luiz Juliano, Afonso Pinto Nazário, Gil Facina, Siu Mui Tsai, Maria Luiza Vilela Oliva,  and Manoel João Batista Castello Girão
16851-16874
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Glucose transporter GLUT1 expression and clinical outcome in solid tumors: a systematic review and meta-analysis

Glucose transporter GLUT1 expression and clinical outcome in solid tumors: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.15171

Ji Wang, Chenyang Ye, Cong Chen, Hanchu Xiong, Binbin Xie, Jichun Zhou, Yongxia Chen, Shu Zheng,  and Linbo Wang
16875-16886
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IL-8 and eNOS polymorphisms predict bevacizumab-based first line treatment outcomes in RAS mutant metastatic colorectal cancer patients

IL-8 and eNOS polymorphisms predict bevacizumab-based first line treatment outcomes in RAS mutant metastatic colorectal cancer patients

https://doi.org/10.18632/oncotarget.14810

Mariantonietta Di Salvatore, Filippo Pietrantonio, Armando Orlandi, Marzia Del Re, Rosa Berenato, Ernesto Rossi, Marta Caporale, Donatella Guarino, Antonia Martinetti, Michele Basso, Roberta Mennitto, Concetta Santonocito, Alessia Mennitto, Giovanni Schinzari, Ilaria Bossi, Ettore Capoluongo, Romano Danesi, Filippo de Braud,  and Carlo Barone
16887-16898
Abstract  |  PDF  |  HTML  |  Order a Reprint

Epigenetic alterations of gastrokine 1 gene expression in gastric cancer

Epigenetic alterations of gastrokine 1 gene expression in gastric cancer

https://doi.org/10.18632/oncotarget.14817

Filomena Altieri, Chiara Stella Di Stadio, Antonella Federico, Giuseppina Miselli, Maurizio De Palma, Emilia Rippa,  and Paolo Arcari
16899-16911
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Physiological characterization of a novel PPAR pan agonist, 2-(4-(5,6-methylenedioxybenzo[d]thiazol-2-yl)-2-methylphenoxy)-2-methylpropanoic acid (MHY2013)

Physiological characterization of a novel PPAR pan agonist, 2-(4-(5,6-methylenedioxybenzo[d]thiazol-2-yl)-2-methylphenoxy)-2-methylpropanoic acid (MHY2013)

https://doi.org/10.18632/oncotarget.14818

Hye Jin An, Bonggi Lee, Dae Hyun Kim, Eun Kyeong Lee, Ki Wung Chung, Min Hi Park, Hyoung Oh Jeong, Sung Min Kim, Kyoung Mi Moon, Ye Ra Kim, Seong Jin Kim, Hwi Young Yun, Pusoon Chun, Byung Pal Yu, Hyung Ryong Moon,  and Hae Young Chung
16912-16924
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activation of PI3K in response to high glucose leads to regulation of SOCS-3 and STAT1/3 signals and induction of glomerular mesangial extracellular matrix formation

Activation of PI3K in response to high glucose leads to regulation of SOCS-3 and STAT1/3 signals and induction of glomerular mesangial extracellular matrix formation

https://doi.org/10.18632/oncotarget.14808

Meei-Ling Sheu, Chin-Chang Shen, Jia-Rong Jheng,  and Chih-Kang Chiang
16925-16938
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epidemiology and survival outcome of breast cancer in a nationwide study

Epidemiology and survival outcome of breast cancer in a nationwide study

https://doi.org/10.18632/oncotarget.15207

Fu-Chao Liu, Huan-Tang Lin, Chang-Fu Kuo, Lai-Chu See, Meng-Jiun Chiou,  and Huang-Ping Yu
16939-16950
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ELF3 is a negative regulator of epithelial-mesenchymal transition in ovarian cancer cells

ELF3 is a negative regulator of epithelial-mesenchymal transition in ovarian cancer cells

https://doi.org/10.18632/oncotarget.15208

Tsz-Lun Yeung, Cecilia S. Leung, Kwong-Kwok Wong, Arthur Gutierrez-Hartmann, Joseph Kwong, David M. Gershenson,  and Samuel C. Mok
16951-16963
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Pre-radiotherapy neutrophil-to-lymphocyte ratio as an independent prognostic factor in patients with locally advanced hepatocellular carcinoma treated with radiotherapy

Pre-radiotherapy neutrophil-to-lymphocyte ratio as an independent prognostic factor in patients with locally advanced hepatocellular carcinoma treated with radiotherapy

https://doi.org/10.18632/oncotarget.15209

Seok Hyun Son, Eun Young Park, Hee Hyun Park, Chul Seung Kay,  and Hong Seok Jang
16964-16971
Abstract  |  PDF  |  HTML  |  Order a Reprint

Growth differentiation factor 15 induces growth and metastasis of human liver cancer stem-like cells via AKT/GSK-3β/β-catenin signaling

Growth differentiation factor 15 induces growth and metastasis of human liver cancer stem-like cells via AKT/GSK-3β/β-catenin signaling

https://doi.org/10.18632/oncotarget.15216

Qiong Xu, Hai-Xu Xu, Jin-Ping Li, Song Wang, Zheng Fu, Jing Jia, Li Wang, Zhi-Feng Zhu, Rong Lu,  and Zhi Yao
16972-16987
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

N-acetyl-cysteine attenuates remifentanil-induced postoperative hyperalgesia via inhibiting matrix metalloproteinase-9 in dorsal root ganglia

N-acetyl-cysteine attenuates remifentanil-induced postoperative hyperalgesia via inhibiting matrix metalloproteinase-9 in dorsal root ganglia

https://doi.org/10.18632/oncotarget.15217

Yue Liu, Yuan Ni, Wei Zhang, Yu-E Sun, Zhengliang Ma,  and Xiaoping Gu
16988-17001
Abstract  |  PDF  |  HTML  |  Order a Reprint

A versatile system for rapid multiplex genome-edited CAR T cell generation

A versatile system for rapid multiplex genome-edited CAR T cell generation

https://doi.org/10.18632/oncotarget.15218

Jiangtao Ren, Xuhua Zhang, Xiaojun Liu, Chongyun Fang, Shuguang Jiang, Carl H. June,  and Yangbing Zhao
17002-17011
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Autocrine and paracrine STIP1 signaling promote osteolytic bone metastasis in renal cell carcinoma

Autocrine and paracrine STIP1 signaling promote osteolytic bone metastasis in renal cell carcinoma

https://doi.org/10.18632/oncotarget.15222

Jiang Wang, Hongbo You, Jun Qi, Caihong Yang, Ye Ren,  and Hao Cheng
17012-17026
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FOXM1 promotes the progression of prostate cancer by regulating PSA gene transcription

FOXM1 promotes the progression of prostate cancer by regulating PSA gene transcription

https://doi.org/10.18632/oncotarget.15224

Youhong Liu, Yijun Liu, Bowen Yuan, Linglong Yin, Yuchong Peng, Xiaohui Yu, Weibing Zhou, Zhicheng Gong, Jianye Liu, Leye He,  and Xiong Li
17027-17037
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The mutational landscape of ocular marginal zone lymphoma identifies frequent alterations in TNFAIP3 followed by mutations in TBL1XR1 and CREBBP

The mutational landscape of ocular marginal zone lymphoma identifies frequent alterations in TNFAIP3 followed by mutations in TBL1XR1 and CREBBP

https://doi.org/10.18632/oncotarget.14928

Hyunchul Jung, Hae Yong Yoo, Seung Ho Lee, Sohyun Shin, Sang Cheol Kim, Sejoon Lee, Je-Gun Joung, Jae-Yong Nam, Daeun Ryu, Jae Won Yun, Jung Kyoon Choi, Ambarnil Ghosh, Kyeong Kyu Kim, Seok Jin Kim, Won Seog Kim, Woong-Yang Park,  and Young-Hyeh Ko
17038-17049
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Surgery-induced monocytic myeloid-derived suppressor cells expand regulatory T cells in lung cancer

Surgery-induced monocytic myeloid-derived suppressor cells expand regulatory T cells in lung cancer

https://doi.org/10.18632/oncotarget.14991

Jun Wang, Liu Yang, Lu Yu, Yi-Yin Wang, Rui Chen, Jing Qian, Zhi-Peng Hong,  and Xiao-San Su
17050-17058
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Derlin-1 overexpression confers poor prognosis in muscle invasive bladder cancer and contributes to chemoresistance and invasion through PI3K/AKT and ERK/MMP signaling

Derlin-1 overexpression confers poor prognosis in muscle invasive bladder cancer and contributes to chemoresistance and invasion through PI3K/AKT and ERK/MMP signaling

https://doi.org/10.18632/oncotarget.15001

Qianze Dong, Lin Fu, Yue Zhao, Shutao Tan,  and Enhua Wang
17059-17069
Abstract  |  PDF  |  HTML  |  Order a Reprint

Whole-genome sequencing identifies new genetic alterations in meningiomas

Whole-genome sequencing identifies new genetic alterations in meningiomas

https://doi.org/10.18632/oncotarget.15043

Mei Tang, Heng Wei, Lu Han, Jiaojiao Deng, Yuelong Wang, Meijia Yang, Yani Tang, Gang Guo, Liangxue Zhou,  and Aiping Tong
17070-17080
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A panel of microRNA signature in serum for colorectal cancer diagnosis

A panel of microRNA signature in serum for colorectal cancer diagnosis

https://doi.org/10.18632/oncotarget.15059

Mingxia Zhu, Zebo Huang, Danxia Zhu, Xin Zhou, Xia Shan, Lian-wen Qi, Lirong Wu, Wenfang Cheng, Jun Zhu, Lan Zhang, Huo Zhang, Yan Chen, Wei Zhu, Tongshan Wang,  and Ping Liu
17081-17091
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Time trends in the prevalence and epidemiological characteristics of neural tube defects in Liaoning Province, China, 2006-2015: A population-based study

Time trends in the prevalence and epidemiological characteristics of neural tube defects in Liaoning Province, China, 2006-2015: A population-based study

https://doi.org/10.18632/oncotarget.15060

Tie-Ning Zhang, Ting-Ting Gong, Yan-Ling Chen, Qi-Jun Wu, Yuan Zhang, Cheng-Zhi Jiang, Jing Li, Li-Li Li, Chen Zhou,  and Yan-Hong Huang
17092-17104
Abstract  |  PDF  |  HTML  |  Order a Reprint

Modeling amplified p53 responses under DNA-PK inhibition in DNA damage response

Modeling amplified p53 responses under DNA-PK inhibition in DNA damage response

https://doi.org/10.18632/oncotarget.15062

Tingzhe Sun, Xinda Li,  and Pingping Shen
17105-17114
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Investigations in the possibility of early detection of colorectal cancer by gas chromatography/triple-quadrupole mass spectrometry

Investigations in the possibility of early detection of colorectal cancer by gas chromatography/triple-quadrupole mass spectrometry

https://doi.org/10.18632/oncotarget.15081

Shin Nishiumi, Takashi Kobayashi, Shuichi Kawana, Yumi Unno, Takero Sakai, Koji Okamoto, Yasuhide Yamada, Kazuki Sudo, Taiki Yamaji, Yutaka Saito, Yukihide Kanemitsu, Natsuko Tsuda Okita, Hiroshi Saito, Shoichiro Tsugane, Takeshi Azuma, Noriyuki Ojima,  and Masaru Yoshida
17115-17126
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SOCS3 genetic variants and promoter hypermethylation in patients with chronic hepatitis B

SOCS3 genetic variants and promoter hypermethylation in patients with chronic hepatitis B

https://doi.org/10.18632/oncotarget.15083

Nghiem Xuan Hoan, Hoang Van Tong, Dao Phuong Giang, Bui Khac Cuong, Nguyen Linh Toan, Heiner Wedemeyer, C. Thomas Bock, Peter G. Kremsner, Le Huu Song,  and Thirumalaisamy P. Velavan
17127-17139
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tetraspanin 8 is a novel regulator of ILK-driven β1 integrin adhesion and signaling in invasive melanoma cells

Tetraspanin 8 is a novel regulator of ILK-driven β1 integrin adhesion and signaling in invasive melanoma cells

https://doi.org/10.18632/oncotarget.15084

Manale El Kharbili, Clement Robert, Tiffany Witkowski, Emmanuelle Danty-Berger, Laetitia Barbollat-Boutrand, Ingrid Masse, Nicolas Gadot, Arnaud de la Fouchardiere, Paul C. McDonald, Shoukat Dedhar, Francois Le Naour, Francoise Degoul,  and Odile Berthier-Vergnes
17140-17155
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

KIAA1199 is induced by inflammation and enhances malignant phenotype in pancreatic cancer

KIAA1199 is induced by inflammation and enhances malignant phenotype in pancreatic cancer

https://doi.org/10.18632/oncotarget.15052

Shiro Kohi, Norihiro Sato, Atsuhiro Koga, YNobutaka Matayoshi,  and Keiji Hirata
17156-17163
Abstract  |  PDF  |  HTML  |  Order a Reprint

ATM mutations and E-cadherin expression define sensitivity to EGFR-targeted therapy in colorectal cancer

ATM mutations and E-cadherin expression define sensitivity to EGFR-targeted therapy in colorectal cancer

https://doi.org/10.18632/oncotarget.15211

Anna-Lena Geißler, Miriam Geißler, Daniel Kottmann, Lisa Lutz, Christiane D. Fichter, Ralph Fritsch, Britta Weddeling, Frank Makowiec, Martin Werner,  and Silke Lassmann
17164-17190
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-34a promotes DCs development and inhibits their function on T cell activation by targeting WNT1

MiR-34a promotes DCs development and inhibits their function on T cell activation by targeting WNT1

https://doi.org/10.18632/oncotarget.15228

Anfei Huang, Yi Yang, Si Chen, Fei Xia, Di Sun, Deyu Fang, Sidong Xiong, Liping Jin,  and Jinping Zhang
17191-17201
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinicopathologic and prognostic significance of human epidermal growth factor receptor in patients with gastric cancer: An updated meta-analysis

Clinicopathologic and prognostic significance of human epidermal growth factor receptor in patients with gastric cancer: An updated meta-analysis

https://doi.org/10.18632/oncotarget.15231

Zhiqiao Zhang, Hongfeng Tang, Jixin Lin, Yunzhao Hu, Guanying Luo, Zhaowen Luo, Canchang Cheng,  and Peng Wang
17202-17215
Abstract  |  PDF  |  HTML  |  Order a Reprint

Resveratrol induces cell cycle arrest and apoptosis with docetaxel in prostate cancer cells via a p53/ p21WAF1/CIP1 and p27KIP1 pathway

Resveratrol induces cell cycle arrest and apoptosis with docetaxel in prostate cancer cells via a p53/ p21WAF1/CIP1 and p27KIP1 pathway

https://doi.org/10.18632/oncotarget.15303

Santosh Kumar Singh, Saswati Banerjee, Edward P. Acosta, James W. Lillard,  and Rajesh Singh
17216-17228
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical Research Papers

Preoperative nomogram for identifying invasive pulmonary adenocarcinoma in patients with pure ground-glass nodule: A multi-institutional study

Preoperative nomogram for identifying invasive pulmonary adenocarcinoma in patients with pure ground-glass nodule: A multi-institutional study

https://doi.org/10.18632/oncotarget.11236

Yunlang She, Lilan Zhao, Chenyang Dai, Yijiu Ren, Junyan Zha, Huikang Xie, Sen Jiang, Jingyun Shi, Shunbin Shi, Weirong Shi, Bing Yu, Gening Jiang, Ke Fei, Yongbing Chen,  and Chang Chen
17229-17238
Abstract  |  PDF  |  HTML  |  Order a Reprint

Association of FCGR2A/FCGR3A variant rs2099684 with Takayasu arteritis in the Han Chinese population

Association of FCGR2A/FCGR3A variant rs2099684 with Takayasu arteritis in the Han Chinese population

https://doi.org/10.18632/oncotarget.12738

Si Chen, Xiaoting Wen, Jing Li, Yuan Li, Liubing Li, Xinping Tian, Hui Yuan, Fengchun Zhang,  and Yongzhe Li
17239-17245
Abstract  |  PDF  |  HTML  |  Order a Reprint

Effectiveness and safety of sorafenib in the treatment of unresectable and advanced intrahepatic cholangiocarcinoma: a pilot study

Effectiveness and safety of sorafenib in the treatment of unresectable and advanced intrahepatic cholangiocarcinoma: a pilot study

https://doi.org/10.18632/oncotarget.12825

Xiangji Luo, Weidong Jia, Zhiyong Huang, Xiangcheng Li, Baocai Xing, Xiaoqing Jiang, Jun Li, Anfeng Si, Tian Yang, Chunfang Gao, Wan Yee Lau,  and Feng Shen
17246-17257
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impact of surgical margin status on the outcome of bladder cancer treated by radical cystectomy: a meta-analysis

Impact of surgical margin status on the outcome of bladder cancer treated by radical cystectomy: a meta-analysis

https://doi.org/10.18632/oncotarget.12907

Xuwei Hong, Tieqiu Li, Fengsheng Ling, Dashan Yang, Lina Hou, Fei Li,  and Wanlong Tan
17258-17269
Abstract  |  PDF  |  HTML  |  Order a Reprint

An open label phase II study evaluating first-line EGFR tyrosine kinase inhibitor erlotinib in non-small cell lung cancer patients with tumors showing high EGFR gene copy number

An open label phase II study evaluating first-line EGFR tyrosine kinase inhibitor erlotinib in non-small cell lung cancer patients with tumors showing high EGFR gene copy number

https://doi.org/10.18632/oncotarget.13793

Ewa Szutowicz-Zielińska, Krzysztof Konopa, Anna Kowalczyk, Małgorzata Suszko-Każarnowicz, Renata Duchnowska, Aleksandra Szczęsna, Magdalena Ratajska, Aleksander Sowa, Janusz Limon, Wojciech Biernat, Tomasz Burzykowski, Jacek Jassem,  and Rafał Dziadziuszko
17270-17278
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

Tumour-derived exosomes as a signature of pancreatic cancer - liquid biopsies as indicators of tumour progression

Tumour-derived exosomes as a signature of pancreatic cancer - liquid biopsies as indicators of tumour progression

https://doi.org/10.18632/oncotarget.13973

Zarin Nuzhat, Vyjayanthi Kinhal, Shayna Sharma, Gregory E. Rice, Virendra Joshi,  and Carlos Salomon
17279-17291
Abstract  |  PDF  |  HTML  |  Order a Reprint

Hepatitis B virus-associated intrahepatic cholangiocarcinoma: a malignancy of distinctive characteristics between hepatocellular carcinoma and intrahepatic cholangiocarcinoma

Hepatitis B virus-associated intrahepatic cholangiocarcinoma: a malignancy of distinctive characteristics between hepatocellular carcinoma and intrahepatic cholangiocarcinoma

https://doi.org/10.18632/oncotarget.14079

Seogsong Jeong, Ying Tong, Meng Sha, Jinyang Gu,  and Qiang Xia
17292-17300
Abstract  |  PDF  |  HTML  |  Order a Reprint

Induced cancer stem cells generated by radiochemotherapy and their therapeutic implications

Induced cancer stem cells generated by radiochemotherapy and their therapeutic implications

https://doi.org/10.18632/oncotarget.14230

Xiewan Chen, Rongxia Liao, Dezhi Li,  and Jianguo Sun
17301-17312
Abstract  |  PDF  |  HTML  |  Order a Reprint

Immunotherapy: incorporation in the evolving paradigm of renal cancer management and future prospects

Immunotherapy: incorporation in the evolving paradigm of renal cancer management and future prospects

https://doi.org/10.18632/oncotarget.14388

Kenneth G. Liu, Sorab Gupta,  and Sanjay Goel
17313-17327
Abstract  |  PDF  |  HTML  |  Order a Reprint

Potential roles of microRNAs and ROS in colorectal cancer: diagnostic biomarkers and therapeutic targets

Potential roles of microRNAs and ROS in colorectal cancer: diagnostic biomarkers and therapeutic targets

https://doi.org/10.18632/oncotarget.14461

Jingmei Lin, Chia-Chen Chuang,  and Li Zuo
17328-17346
Abstract  |  PDF  |  HTML  |  Order a Reprint

Overexpression of lncRNA ANRIL up-regulates VEGF expression and promotes angiogenesis of diabetes mellitus combined with cerebral infarction by activating NF-κB signaling pathway in a rat model

Overexpression of lncRNA ANRIL up-regulates VEGF expression and promotes angiogenesis of diabetes mellitus combined with cerebral infarction by activating NF-κB signaling pathway in a rat model

https://doi.org/10.18632/oncotarget.14468

Bo Zhang, Dan Wang, Tie-Feng Ji, Lei Shi,  and Jin-Lu Yu
17347-17359
Abstract  |  PDF  |  HTML  |  Order a Reprint

Nanoparticle albumin-bound paclitaxel as neoadjuvant chemotherapy of breast cancer: a systematic review and meta-analysis

Nanoparticle albumin-bound paclitaxel as neoadjuvant chemotherapy of breast cancer: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.14477

Yu Zong, Jiayi Wu,  and Kunwei Shen
17360-17372
Abstract  |  PDF  |  HTML  |  Order a Reprint

Biological functions of CDK5 and potential CDK5 targeted clinical treatments

Biological functions of CDK5 and potential CDK5 targeted clinical treatments

https://doi.org/10.18632/oncotarget.14538

Alison Shupp, Mathew C. Casimiro,  and Richard G. Pestell
17373-17382
Abstract  |  PDF  |  HTML  |  Order a Reprint

Rectal/urinary toxicity after hypofractionated vs conventional radiotherapy in low/intermediate risk localized prostate cancer: systematic review and meta analysis

Rectal/urinary toxicity after hypofractionated vs conventional radiotherapy in low/intermediate risk localized prostate cancer: systematic review and meta analysis

https://doi.org/10.18632/oncotarget.14798

Rossella Di Franco, Valentina Borzillo, Vincenzo Ravo, Gianluca Ametrano, Sara Falivene, Fabrizio Cammarota, Sabrina Rossetti, Francesco Jacopo Romano, Carmine D’Aniello, Carla Cavaliere, Gelsomina Iovane, Raffaele Piscitelli, Massimiliano Berretta, Paolo Muto,  and Gaetano Facchini
17383-17395
Abstract  |  PDF  |  HTML  |  Order a Reprint

Systematic review of resecting primary tumor in MNETs patients with unresectable liver metastases

Systematic review of resecting primary tumor in MNETs patients with unresectable liver metastases

https://doi.org/10.18632/oncotarget.14156

Jingfei Guo, Qian Zhang, Xinyu Bi, Jianguo Zhou, Zhiyu Li, Zhen Huang, Yefan Zhang, Muxing Li, Xiao Chen, Xuhui Hu, Chi Yihebali, Junbo Liang, Jianmei Liu, Jianjun Zhao, Jianqiang Cai,  and Hong Zhao
17396-17405
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Corrections

Correction: miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer

Correction: miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer

https://doi.org/10.18632/oncotarget.15921

Yinghong Pan, Gordon Robertson, Lykke Pedersen, Emilia Lim, Anadulce Hernandez-Herrera, Amy C. Rowat, Sagar L. Patil, Clara K. Chan, Yunfei Wen, Xinna Zhang, Upal Basu-Roy, Alka Mansukhani, Andy Chu, Payal Sipahimalani, Reanne Bowlby, Denise Brooks, Nina Thiessen, Cristian Coarfa, Yussanne Ma, Richard A. Moore, Jacquie E. Schein, Andrew J. Mungall, Jinsong Liu, Chad V. Pecot, Anil K. Sood, Steven J.M. Jones, Marco A. Marra,  and Preethi H. Gunaratne
17406-17406
Correction  |  PDF


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