Oncotarget

Vol 8, No 8

February 21, 2017

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Transgenes expressed in Ba/F3 cells are prone to acquiring additional mutations during factor withdrawal, from Watanabe-Smith, et al.

Table of Contents

News

The purpose of repurposing

The purpose of repurposing

https://doi.org/10.18632/oncotarget.14806

James E. Barrett,  and Felix J. Kim
12534-12535
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FQI1: a transcription-methylation switch for cancer

FQI1: a transcription-methylation switch for cancer

https://doi.org/10.18632/oncotarget.15087

Olga A. Guryanova,  and Jonathan D. Licht
12536-12537
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Turn to TCRs when CARs fail

Turn to TCRs when CARs fail

https://doi.org/10.18632/oncotarget.15088

Hans J. Stauss
12538-12539
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Dissecting genetic risk factors in breast cancer

Dissecting genetic risk factors in breast cancer

https://doi.org/10.18632/oncotarget.15089

Carly M. Harro,  and Alvaro N.A. Monteiro
12540-12541
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Characterizing the last holdouts

Characterizing the last holdouts

https://doi.org/10.18632/oncotarget.15090

Erin L. Stewart,  and Ming-Sound Tsao
12542-12543
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Editorial: Neuroscience

Protecting the developing brain by 17βestradiol

Protecting the developing brain by 17βestradiol

https://doi.org/10.18632/oncotarget.14979

Julien Pansiot, Jérome Mairesse,  and Olivier Baud
12544-12545
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Targeting JNK to prevent antiretroviral neuropathy

Targeting JNK to prevent antiretroviral neuropathy

https://doi.org/10.18632/oncotarget.15091

Nicoletta Galeotti
12546-12547
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Novel neurobiological roles of UBE3A

Novel neurobiological roles of UBE3A

https://doi.org/10.18632/oncotarget.15105

Jiandong Sun, Michel Baudry,  and Xiaoning Bi
12548-12549
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Targeting the equilibrative nucleoside transporter ENT1 in Huntington disease

Targeting the equilibrative nucleoside transporter ENT1 in Huntington disease

https://doi.org/10.18632/oncotarget.15111

Xavier Guitart, Yijuang Chern,  and Sergi Ferré
12550-12551
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Huntington’s disease: of mice and men

Huntington’s disease: of mice and men

https://doi.org/10.18632/oncotarget.15129

Emma Yhnell
12552-12553
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Targeting Kv7 channels in pain pathways

Targeting Kv7 channels in pain pathways

https://doi.org/10.18632/oncotarget.15261

Ivan Rivera-Arconada, Jorge Vicente-Baz,  and Jose Antonio Lopez-Garcia
12554-12555
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Central neuronal functions of histamine H4 receptors

Central neuronal functions of histamine H4 receptors

https://doi.org/10.18632/oncotarget.15289

Maria Domenica Sanna,  and Nicoletta Galeotti
12556-12557
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Priority Research Papers

Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer

Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer

https://doi.org/10.18632/oncotarget.14894

Martina S.J. McDermott, Alexander A. Chumanevich, Chang-uk Lim, Jiaxin Liang, Mengqian Chen, Serena Altilia, David Oliver, James M. Rae, Michael Shtutman, Hippokratis Kiaris, Balázs Győrffy, Igor B. Roninson,  and Eugenia V. Broude
12558-12575
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The repurposed anthelmintic mebendazole in combination with trametinib suppresses refractory NRASQ61K melanoma

The repurposed anthelmintic mebendazole in combination with trametinib suppresses refractory NRASQ61K melanoma

https://doi.org/10.18632/oncotarget.14990

Cynthia M. Simbulan-Rosenthal, Sivanesan Dakshanamurthy, Anirudh Gaur, You-Shin Chen, Hong-Bin Fang, Maryam Abdussamad, Hengbo Zhou, John Zapas, Valerie Calvert, Emanuel F. Petricoin, Michael B. Atkins, Stephen W. Byers,  and Dean S. Rosenthal
12576-12595
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Analysis of acquired mutations in transgenes arising in Ba/F3 transformation assays: findings and recommendations

Analysis of acquired mutations in transgenes arising in Ba/F3 transformation assays: findings and recommendations

https://doi.org/10.18632/oncotarget.15392

Kevin Watanabe-Smith, Jamila Godil, Anupriya Agarwal, Cristina Tognon,  and Brian Druker
12596-12606
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Research Papers: Gerotarget (Focus on Aging)

Variants in ANRIL gene correlated with its expression contribute to myocardial infarction risk

Variants in ANRIL gene correlated with its expression contribute to myocardial infarction risk

https://doi.org/10.18632/oncotarget.14721

Jie Cheng, Meng-Yun Cai, Yu-Ning Chen, Zhi-Cheng Li, Sai-Sai Tang, Xi-Li Yang, Can Chen, Xinguang Liu,  and Xing-dong Xiong
12607-12619
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Research Papers: Pathology

Detection and localization of viral infection in the pancreas of patients with type 1 diabetes using short fluorescently-labelled oligonucleotide probes

Detection and localization of viral infection in the pancreas of patients with type 1 diabetes using short fluorescently-labelled oligonucleotide probes

https://doi.org/10.18632/oncotarget.14896

Niels Busse, Federico Paroni, Sarah J. Richardson, Jutta E. Laiho, Maarit Oikarinen, Gun Frisk, Heikki Hyöty, Eelco de Koning, Noel G. Morgan,  and Kathrin Maedler
12620-12636
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Augmenter of liver regeneration protects against carbon tetrachloride-induced liver injury by promoting autophagy in mice

Augmenter of liver regeneration protects against carbon tetrachloride-induced liver injury by promoting autophagy in mice

https://doi.org/10.18632/oncotarget.14478

Hongbo Shi, Weijia Han, Honglin Shi, Feng Ren, Dexi Chen, Yu Chen,  and Zhongping Duan
12637-12648
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Research Papers: Immunology

Dishevelled2 promotes apoptosis and inhibits inflammatory cytokine secretion in rheumatoid arthritis fibroblast-like synoviocytes through crosstalk with the NF-κB pathway

Dishevelled2 promotes apoptosis and inhibits inflammatory cytokine secretion in rheumatoid arthritis fibroblast-like synoviocytes through crosstalk with the NF-κB pathway

https://doi.org/10.18632/oncotarget.15172

Xing Zhen Liu, Jie Fan, Ke Qi, Shu Peng Liu, Wei Dong Xu, Ying Gao, Xiao Dan Gu, Jia Li, Chen Guang Bai, Ye Qing Shi, Lan Ling Zhang,  and Dong Bao Zhao
12649-12663
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Research Papers

CD74 and intratumoral immune response in breast cancer

CD74 and intratumoral immune response in breast cancer

https://doi.org/10.18632/oncotarget.8610

Zhi-Qiang Wang, Katy Milne, John R. Webb,  and Peter H. Watson
12664-12674
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Angiostatic actions of capsicodendrin through selective inhibition of VEGFR2-mediated AKT signaling and disregulated autophagy

Angiostatic actions of capsicodendrin through selective inhibition of VEGFR2-mediated AKT signaling and disregulated autophagy

https://doi.org/10.18632/oncotarget.9307

Christopher C. Pan, Nirav Shah, Sanjay Kumar, Sarah E. Wheeler, Jason Cinti, Dale G. Hoyt, Christine E. Beattie, Min An, Karthikeyan Mythreye, L. Harinantenaina Rakotondraibe,  and Nam Y. Lee
12675-12685
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MERS-CoV virus-like particles produced in insect cells induce specific humoural and cellular imminity in rhesus macaques

MERS-CoV virus-like particles produced in insect cells induce specific humoural and cellular imminity in rhesus macaques

https://doi.org/10.18632/oncotarget.8475

Chong Wang, Xuexing Zheng, Weiwei Gai, Yongkun Zhao, Hualei Wang, Haijun Wang, Na Feng, Hang Chi, Boning Qiu, Nan Li, Tiecheng Wang, Yuwei Gao, Songtao Yang,  and Xianzhu Xia
12686-12694
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Analysis of the inhibitors of apoptosis identifies BIRC3 as a facilitator of malignant progression in glioma

Analysis of the inhibitors of apoptosis identifies BIRC3 as a facilitator of malignant progression in glioma

https://doi.org/10.18632/oncotarget.8657

Loyola V. Gressot, Tiffany Doucette, Yuhui Yang, Gregory N. Fuller, Ganiraju Manyam, Arvind Rao, Khatri Latha,  and Ganesh Rao
12695-12704
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Amplification of ACK1 promotes gastric tumorigenesis via ECD-dependent p53 ubiquitination degradation

Amplification of ACK1 promotes gastric tumorigenesis via ECD-dependent p53 ubiquitination degradation

https://doi.org/10.18632/oncotarget.6194

Song-Hui Xu, Jin-Zhou Huang, Min Chen, Ming Zeng, Fei-Yan Zou, De Chen,  and Guang-Rong Yan
12705-12716
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The comprehensive therapeutic effects of rectal surgery are better in laparoscopy: a systematic review and meta-analysis

The comprehensive therapeutic effects of rectal surgery are better in laparoscopy: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.14215

Jiabin Zheng, Xingyu Feng, Zifeng Yang, Weixian Hu, Yuwen Luo,  and Yong Li
12717-12729
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Glutamate induces autophagy via the two-pore channels in neural cells

Glutamate induces autophagy via the two-pore channels in neural cells

https://doi.org/10.18632/oncotarget.14404

Gustavo J. S. Pereira, Manuela Antonioli, Hanako Hirata, Rodrigo P. Ureshino, Aline R. Nascimento, Claudia Bincoletto, Tiziana Vescovo, Mauro Piacentini, Gian Maria Fimia,  and Soraya S. Smaili
12730-12740
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Mitotic catastrophe and cell cycle arrest are alternative cell death pathways executed by bortezomib in rituximab resistant B-cell lymphoma cells

Mitotic catastrophe and cell cycle arrest are alternative cell death pathways executed by bortezomib in rituximab resistant B-cell lymphoma cells

https://doi.org/10.18632/oncotarget.14405

Juan J. Gu, Gregory P. Kaufman, Cory Mavis, Myron S Czuczman,  and Francisco J. Hernandez-Ilizaliturri
12741-12753
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Δ40p53 is involved in the inactivation of autophagy and contributes to inhibition of cell death in HCT116-Δ40p53 cells

Δ40p53 is involved in the inactivation of autophagy and contributes to inhibition of cell death in HCT116-Δ40p53 cells

https://doi.org/10.18632/oncotarget.14460

Yunjin Zang, Ying Shi, Kai Liu, Luxin Qiao, Xianghua Guo,  and Dexi Chen
12754-12763
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The combination effect of homoharringtonine and ibrutinib on FLT3-ITD mutant acute myeloid leukemia

The combination effect of homoharringtonine and ibrutinib on FLT3-ITD mutant acute myeloid leukemia

https://doi.org/10.18632/oncotarget.14463

Xia Li, Xiufeng Yin, Huafeng Wang, Jiansong Huang, Mengxia Yu, Zhixin Ma, Chenying Li, Yile Zhou, Xiao Yan, ShuJuan Huang,  and Jie Jin
12764-12774
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MHY1485 ameliorates UV-induced skin cell damages via activating mTOR-Nrf2 signaling

MHY1485 ameliorates UV-induced skin cell damages via activating mTOR-Nrf2 signaling

https://doi.org/10.18632/oncotarget.14299

Bo Yang, Qiu-yun Xu, Chun-yan Guo, Jin-wen Huang, Shu-mei Wang, Yong-mei Li, Ying Tu, Li He, Zhi-gang Bi, Chao Ji,  and Bo Cheng
12775-12783
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Prevalence of psychological symptoms among Ebola survivors and healthcare workers during the 2014-2015 Ebola outbreak in Sierra Leone: a cross-sectional study

Prevalence of psychological symptoms among Ebola survivors and healthcare workers during the 2014-2015 Ebola outbreak in Sierra Leone: a cross-sectional study

https://doi.org/10.18632/oncotarget.14498

Dong Ji, Ying-Jie Ji, Xue-Zhang Duan, Wen-Gang Li, Zhi-Qiang Sun, Xue-Ai Song, Yu-Hua Meng, Hong-Mei Tang, Fang Chu, Xiao-Xia Niu, Guo-Feng Chen, Jin Li,  and Hui-Juan Duan
12784-12791
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Protective effects of oxymatrine against arsenic trioxide-induced liver injury

Protective effects of oxymatrine against arsenic trioxide-induced liver injury

https://doi.org/10.18632/oncotarget.12478

Li Li, Qinghai Liu, Long Fan, Wei Xiao, Lei Zhao, Yu Wang, Weiguang Ye, Fei Lan, Bin Jia, Hua Feng, Changman Zhou, Xiuqin Yue, Guogang Xing,  and Tianlong Wang
12792-12799
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Androgen suppresses protein kinase D1 expression through fibroblast growth factor receptor substrate 2 in prostate cancer cells

Androgen suppresses protein kinase D1 expression through fibroblast growth factor receptor substrate 2 in prostate cancer cells

https://doi.org/10.18632/oncotarget.14536

Liyong Zhang, Zhenlong Zhao, Shuping Xu, Manuj Tandon, Courtney R. LaValle, Fan Deng,  and Q. Jane Wang
12800-12811
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High TMPRSS11D protein expression predicts poor overall survival in non-small cell lung cancer

High TMPRSS11D protein expression predicts poor overall survival in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.14559

Xiang Cao, Zhiyuan Tang, Fang Huang, Qin Jin, Xiaoyu Zhou,  and Jiahai Shi
12812-12819
Abstract  |  PDF  |  HTML  |  Order a Reprint

Aberrant methylation patterns in colorectal cancer: a meta-analysis

Aberrant methylation patterns in colorectal cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.14590

Danielle Fernandes Durso, Maria Giulia Bacalini, Ítalo Faria do Valle, Chiara Pirazzini, Massimiliano Bonafé, Gastone Castellani, Ana Maria Caetano Faria, Claudio Franceschi, Paolo Garagnani,  and Christine Nardini
12820-12830
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma

A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.14606

Xiaoyun Dai, Lingzhi Wang, Amudha Deivasigamni, Chung Yeng Looi, Chandrabose Karthikeyan, Piyush Trivedi, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Frank Arfuso, Arunasalam Dharmarajan, Boon Cher Goh, Kam Man Hui, Alan Prem Kumar, Mohd Rais Mustafa,  and Gautam Sethi
12831-12842
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Preclinical pharmacodynamic evaluation of drug candidate SKLB-178 in the treatment of non-small cell lung cancer

Preclinical pharmacodynamic evaluation of drug candidate SKLB-178 in the treatment of non-small cell lung cancer

https://doi.org/10.18632/oncotarget.14597

Lei Zhong, Jiao Yang, Zhixing Cao, Xin Chen, Yiguo Hu, Linli Li,  and Shengyong Yang
12843-12854
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

AML associated oncofusion proteins PML-RARA, AML1-ETO and CBFB-MYH11 target RUNX/ETS-factor binding sites to modulate H3ac levels and drive leukemogenesis

AML associated oncofusion proteins PML-RARA, AML1-ETO and CBFB-MYH11 target RUNX/ETS-factor binding sites to modulate H3ac levels and drive leukemogenesis

https://doi.org/10.18632/oncotarget.14150

Abhishek A. Singh, Amit Mandoli, Koen H.M. Prange, Marko Laakso,  and Joost H.A. Martens
12855-12865
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CD44v6 overexpression related to metastasis and poor prognosis of colorectal cancer: A meta-analysis

CD44v6 overexpression related to metastasis and poor prognosis of colorectal cancer: A meta-analysis

https://doi.org/10.18632/oncotarget.14163

Ji-Lin Wang, Wen-Yu Su, Yan-Wei Lin, Hua Xiong, Ying-Xuan Chen, Jie Xu,  and Jing-Yuan Fang
12866-12876
Abstract  |  PDF  |  HTML  |  Order a Reprint

High-throughput proteome analysis reveals targeted TRPM8 degradation in prostate cancer

High-throughput proteome analysis reveals targeted TRPM8 degradation in prostate cancer

https://doi.org/10.18632/oncotarget.14178

Swapna Asuthkar, Lusine Demirkhanyan, Samuel Robert Mueting, Alejandro Cohen,  and Eleonora Zakharian
12877-12890
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preoperative neutrophil-lymphocyte ratio can significantly predict mortality outcomes in patients with non-muscle invasive bladder cancer undergoing transurethral resection of bladder tumor

Preoperative neutrophil-lymphocyte ratio can significantly predict mortality outcomes in patients with non-muscle invasive bladder cancer undergoing transurethral resection of bladder tumor

https://doi.org/10.18632/oncotarget.14179

Minyong Kang, Chang Wook Jeong, Choel Kwak, Hyeon Hoe Kim,  and Ja Hyeon Ku
12891-12901
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reactive oxygen species mediate heat stress-induced apoptosis via ERK dephosphorylation and Bcl-2 ubiquitination in human umbilical vein endothelial cells

Reactive oxygen species mediate heat stress-induced apoptosis via ERK dephosphorylation and Bcl-2 ubiquitination in human umbilical vein endothelial cells

https://doi.org/10.18632/oncotarget.14186

Li Li, Hongping Tan, Hong Yang, Feng Li, Xuan He, Zhengtao Gu, Ming Zhao,  and Lei Su
12902-12916
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Analysis of circulating tumor cells from lung cancer patients with multiple biomarkers using high-performance size-based microfluidic chip

Analysis of circulating tumor cells from lung cancer patients with multiple biomarkers using high-performance size-based microfluidic chip

https://doi.org/10.18632/oncotarget.14203

Wanlei Gao, Haojun Yuan, Fengxiang Jing, Shan Wu, Hongbo Zhou, Hongju Mao, Qinghui Jin, Jianlong Zhao, Hui Cong,  and Chunping Jia
12917-12928
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The IgH locus 3’ cis-regulatory super-enhancer co-opts AID for allelic transvection

The IgH locus 3’ cis-regulatory super-enhancer co-opts AID for allelic transvection

https://doi.org/10.18632/oncotarget.14585

Sandrine Le Noir, Brice Laffleur, Claire Carrion, Armand Garot, Sandrine Lecardeur, Eric Pinaud, Yves Denizot, Jane Skok,  and Michel Cogné
12929-12940
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Frequent amplification of receptor tyrosine kinase genes in welldifferentiated/ dedifferentiated liposarcoma

Frequent amplification of receptor tyrosine kinase genes in welldifferentiated/ dedifferentiated liposarcoma

https://doi.org/10.18632/oncotarget.14652

Naofumi Asano, Akihiko Yoshida, Sachiyo Mitani, Eisuke Kobayashi, Bunsyo Shiotani, Motokiyo Komiyama, Hiroyuki Fujimoto, Hirokazu Chuman, Hideo Morioka, Morio Matsumoto, Masaya Nakamura, Takashi Kubo, Mamoru Kato, Takashi Kohno, Akira Kawai, Tadashi Kondo,  and Hitoshi Ichikawa
12941-12952
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Dual SYK/JAK inhibition overcomes ibrutinib resistance in chronic lymphocytic leukemia: Cerdulatinib, but not ibrutinib, induces apoptosis of tumor cells protected by the microenvironment

Dual SYK/JAK inhibition overcomes ibrutinib resistance in chronic lymphocytic leukemia: Cerdulatinib, but not ibrutinib, induces apoptosis of tumor cells protected by the microenvironment

https://doi.org/10.18632/oncotarget.14588

Ailin Guo, Pin Lu, Greg Coffey, Pamela Conley, Anjali Pandey,  and Y. Lynn Wang
12953-12967
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Anthelmintic mebendazole enhances cisplatin’s effect on suppressing cell proliferation and promotes differentiation of head and neck squamous cell carcinoma (HNSCC)

Anthelmintic mebendazole enhances cisplatin’s effect on suppressing cell proliferation and promotes differentiation of head and neck squamous cell carcinoma (HNSCC)

https://doi.org/10.18632/oncotarget.14673

Fugui Zhang, Yong Li, Hongmei Zhang, Enyi Huang, Lina Gao, Wenping Luo, Qiang Wei, Jiaming Fan, Dongzhe Song, Junyi Liao, Yulong Zou, Feng Liu, Jianxiang Liu, Jiayi Huang, Dan Guo, Chao Ma, Xue Hu, Li Li, Xiangyang Qu, Liqun Chen, Xinyi Yu, Zhicai Zhang, Tingting Wu, Hue H. Luu, Rex C. Haydon, Jinlin Song, Tong-Chuan He,  and Ping Ji
12968-12982
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prolyl hydroxylase domain protein 3 and asparaginyl hydroxylase factor inhibiting HIF-1 levels are predictive of tumoral behavior and prognosis in hepatocellular carcinoma

Prolyl hydroxylase domain protein 3 and asparaginyl hydroxylase factor inhibiting HIF-1 levels are predictive of tumoral behavior and prognosis in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.14677

Mingyang Ma, Shuyao Hua, Gang Li, Sumei Wang, Xue Cheng, Songqing He, Ping Wu,  and Xiaoping Chen
12983-13002
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Talin-1 interaction network promotes hepatocellular carcinoma progression

Talin-1 interaction network promotes hepatocellular carcinoma progression

https://doi.org/10.18632/oncotarget.14674

Peng Chen, Xiaohu Zheng, Yonggang Zhou, Yechuan Xu, Lixin Zhu,  and Yeben Qian
13003-13014
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Functional assessment of von Willebrand factor expression by cancer cells of non-endothelial origin

Functional assessment of von Willebrand factor expression by cancer cells of non-endothelial origin

https://doi.org/10.18632/oncotarget.14273

Anahita Mojiri, Konstantin Stoletov, Maria Areli Lorenzana Carrillo, Lian Willetts, Saket Jain, Roseline Godbout, Paul Jurasz, Consolato M. Sergi, David D. Eisenstat, John D. Lewis,  and Nadia Jahroudi
13015-13029
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Diagnostic and prognostic utilities of humoral fibulin-3 in malignant pleural mesothelioma: Evidence from a meta-analysis

Diagnostic and prognostic utilities of humoral fibulin-3 in malignant pleural mesothelioma: Evidence from a meta-analysis

https://doi.org/10.18632/oncotarget.14712

Dongxu Pei, Yongwei Li, Xinwei Liu, Sha Yan, Xiaolan Guo, Xiaona Xu,  and Xiaoxia Guo
13030-13038
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A nanocomposite-based electrochemical sensor for non-enzymatic detection of hydrogen peroxide

A nanocomposite-based electrochemical sensor for non-enzymatic detection of hydrogen peroxide

https://doi.org/10.18632/oncotarget.14308

Xin Du, Yuan Chen, Wenhao Dong, Bingkai Han, Min Liu, Qiang Chen,  and Jun Zhou
13039-13047
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Circulating exosomal microRNAs as prognostic biomarkers for non-small-cell lung cancer

Circulating exosomal microRNAs as prognostic biomarkers for non-small-cell lung cancer

https://doi.org/10.18632/oncotarget.14369

Qingyun Liu, Zubin Yu, Shuai Yuan, Weijia Xie, Chengying Li, Zeyao Hu, Ying Xiang, Na Wu, Long Wu, Li Bai,  and Yafei Li
13048-13058
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Analysis of molecular mechanisms of 5-fluorouracil-induced steatosis and inflammation in vitro and in mice

Analysis of molecular mechanisms of 5-fluorouracil-induced steatosis and inflammation in vitro and in mice

https://doi.org/10.18632/oncotarget.14371

Judith Sommer, Abdo Mahli, Kim Freese, Tobias S. Schiergens, Fulya Suzan Kuecuekoktay, Andreas Teufel, Wolfgang E. Thasler, Martina Müller, Anja K. Bosserhoff,  and Claus Hellerbrand
13059-13072
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Maternal butyrate supplementation induces insulin resistance associated with enhanced intramuscular fat deposition in the offspring

Maternal butyrate supplementation induces insulin resistance associated with enhanced intramuscular fat deposition in the offspring

https://doi.org/10.18632/oncotarget.14375

Yanping Huang, Shixing Gao, Jinglong Chen, Elke Albrecht, Ruqian Zhao,  and Xiaojing Yang
13073-13084
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Emetine elicits apoptosis of intractable B-cell lymphoma cells with MYC rearrangement through inhibition of glycolytic metabolism

Emetine elicits apoptosis of intractable B-cell lymphoma cells with MYC rearrangement through inhibition of glycolytic metabolism

https://doi.org/10.18632/oncotarget.14393

Tomohiro Aoki, Kazuyuki Shimada, Akihiko Sakamoto, Keiki Sugimoto, Takanobu Morishita, Yuki Kojima, Satoko Shimada, Seiichi Kato, Chisako Iriyama, Shunsuke Kuno, Yasuhiko Harada, Akihiro Tomita, Fumihiko Hayakawa,  and Hitoshi Kiyoi
13085-13098
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Integrative genomic and transcriptomic analysis for pinpointing recurrent alterations of plant homeodomain genes and their clinical significance in breast cancer

Integrative genomic and transcriptomic analysis for pinpointing recurrent alterations of plant homeodomain genes and their clinical significance in breast cancer

https://doi.org/10.18632/oncotarget.14402

Huimei Yu, Yuanyuan Jiang, Lanxin Liu, Wenqi Shan, Xiaofang Chu, Zhe Yang,  and Zeng-Quan Yang
13099-13115
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Th1high in tumor microenvironment is an indicator of poor prognosis for patients with NSCLC

Th1high in tumor microenvironment is an indicator of poor prognosis for patients with NSCLC

https://doi.org/10.18632/oncotarget.14471

Huang Jian, Shen Fangrong, Huang Haitao, Ling Chunhua,  and Zhang Guangbo
13116-13125
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cell type- and density-dependent effect of 1 T static magnetic field on cell proliferation

Cell type- and density-dependent effect of 1 T static magnetic field on cell proliferation

https://doi.org/10.18632/oncotarget.14480

Lei Zhang, Xinmiao Ji, Xingxing Yang,  and Xin Zhang
13126-13141
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Vitamin D receptor polymorphisms or serum levels as key drivers of breast cancer development? The question of the vitamin D pathway

Vitamin D receptor polymorphisms or serum levels as key drivers of breast cancer development? The question of the vitamin D pathway

https://doi.org/10.18632/oncotarget.14482

Dino Amadori, Patrizia Serra, Nestory Masalu, Akwilina Pangan, Emanuela Scarpi, Aloyce Maria Bugingo, Deogratias Katabalo, Toni Ibrahim, Alberto Bongiovanni, Giacomo Miserocchi, Chiara Spadazzi, Chiara Liverani, Valentina Turri, Rosanna Tedaldi,  and Laura Mercatali
13142-13156
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.14483

Jianwen Xiong, Xiaoqiang Zhang, Xianglai Chen, Yiping Wei, De-guo Lu, Yun-wei Han, Jianjun Xu,  and Dongliang Yu
13157-13165
Abstract  |  PDF  |  HTML  |  Order a Reprint

Association between PPAP2B gene polymorphisms and coronary heart disease susceptibility in Chinese Han males and females

Association between PPAP2B gene polymorphisms and coronary heart disease susceptibility in Chinese Han males and females

https://doi.org/10.18632/oncotarget.14486

Yu-Xiao Sun, Chuan-Yu Gao, Yang Lu, Xin Fu, Jun-Ge Jia, Yu-Jie Zhao, Lian-Dong Li, Hong-zhi Dui, Xing-Yu Zhang, Zhi-Ying Li, Lei Lei, Wei-Feng Zhang,  and Yi-Qiang Yuan
13166-13173
Abstract  |  PDF  |  HTML  |  Order a Reprint

Oncometabolite succinate promotes angiogenesis by upregulating VEGF expression through GPR91-mediated STAT3 and ERK activation

Oncometabolite succinate promotes angiogenesis by upregulating VEGF expression through GPR91-mediated STAT3 and ERK activation

https://doi.org/10.18632/oncotarget.14485

Xianmin Mu, Ting Zhao, Che Xu, Wei Shi, Biao Geng, Jiajia Shen, Chen Zhang, Jinshun Pan, Jing Yang, Shi Hu, Yuanfang Lv, Hao Wen,  and Qiang You
13174-13185
Abstract  |  PDF  |  HTML  |  Order a Reprint

miRNA-141 attenuates UV-induced oxidative stress via activating Keap1-Nrf2 signaling in human retinal pigment epithelium cells and retinal ganglion cells

miRNA-141 attenuates UV-induced oxidative stress via activating Keap1-Nrf2 signaling in human retinal pigment epithelium cells and retinal ganglion cells

https://doi.org/10.18632/oncotarget.14489

Li-Bo Cheng, Ke-ran Li, Nan Yi, Xiu-miao Li, Feng Wang, Bo Xue, Ying-shun Pan, Jin Yao, Qin Jiang,  and Zhi-feng Wu
13186-13194
Abstract  |  PDF  |  HTML  |  Order a Reprint

Estimation of cell-free circulating EGFR mutation concentration predicts outcomes in NSCLC patients treated with EGFR-TKIs

Estimation of cell-free circulating EGFR mutation concentration predicts outcomes in NSCLC patients treated with EGFR-TKIs

https://doi.org/10.18632/oncotarget.14490

Yan-juan Zhu, Hai-bo Zhang, Yi-hong Liu, Fu-li Zhang, Ya-zhen Zhu, Yong Li, Jian-ping Bai, Li-rong Liu, Yan-chun Qu, Xin Qu, Xian Chen, Yan Li,  and Guang-juan Zheng
13195-13205
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Predictive value of glucose transporter-1 and glucose transporter-3 for survival of cancer patients: A meta-analysis

Predictive value of glucose transporter-1 and glucose transporter-3 for survival of cancer patients: A meta-analysis

https://doi.org/10.18632/oncotarget.14570

Xiu Chen, Peng Lu, Siying Zhou, Lei Zhang, Jian-hua Zhao,  and Jin-hai Tang
13206-13213
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Galectin-1 inhibits oral-intestinal allergy syndrome

Galectin-1 inhibits oral-intestinal allergy syndrome

https://doi.org/10.18632/oncotarget.14571

Rui-Di Xie, Ling-Zhi Xu, Li-Tao Yang, Shuai Wang, Qi Liu, Zhi-Gang Liu,  and Ping-Chang Yang
13214-13222
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome

Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome

https://doi.org/10.18632/oncotarget.14656

Valeriana Cesarini, Maurizio Martini, Lucia Ricci Vitiani, Giovanni Luca Gravina, Silvia Di Agostino, Grazia Graziani, Quintino Giorgio D’Alessandris, Roberto Pallini, Luigi M. Larocca, Pellegrino Rossi, Emmanuele A. Jannini,  and Susanna Dolci
13223-13239
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The roles of RRP15 in nucleolar formation, ribosome biogenesis and checkpoint control in human cells

The roles of RRP15 in nucleolar formation, ribosome biogenesis and checkpoint control in human cells

https://doi.org/10.18632/oncotarget.14658

Zhixiong Dong, Changjun Zhu, Qimin Zhan,  and Wei Jiang
13240-13252
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

microRNA-625 inhibits tumorigenicity by suppressing proliferation, migration and invasion in malignant melanoma

microRNA-625 inhibits tumorigenicity by suppressing proliferation, migration and invasion in malignant melanoma

https://doi.org/10.18632/oncotarget.14710

Wei Fang, Yibin Fan, Zhenzong Fa, Jinhua Xu, Hongyu Yu, Pu Li,  and Julin Gu
13253-13263
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-34a regulates liver regeneration and the development of liver cancer in rats by targeting Notch signaling pathway

MicroRNA-34a regulates liver regeneration and the development of liver cancer in rats by targeting Notch signaling pathway

https://doi.org/10.18632/oncotarget.14807

Xiao-Ping Wang, Jian Zhou, Ming Han, Chuan-Bao Chen, Yi-Tao Zheng, Xiao-Shun He,  and Xiao-Peng Yuan
13264-13276
Abstract  |  PDF  |  HTML  |  Order a Reprint

Differential regulation of cellular functions by the C-termini of transmembrane 4 L six family proteins in 2- or 3-dimensional environment

Differential regulation of cellular functions by the C-termini of transmembrane 4 L six family proteins in 2- or 3-dimensional environment

https://doi.org/10.18632/oncotarget.14809

Jin-Gyu Cheong, Dae-Geun Song, Haeng Eun Song, Fedor Berditchevski, Seo Hee Nam, Jae Woo Jung, Hye-Jin Kim, Ji Eon Kim, Somi Kim, Jihye Ryu, Chang Yun Cho, Kyung-Min Lee,  and Jung Weon Lee
13277-13292
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Albumin to gamma-glutamyltransferase ratio as a prognostic indicator in intrahepatic cholangiocarcinoma after curative resection

Albumin to gamma-glutamyltransferase ratio as a prognostic indicator in intrahepatic cholangiocarcinoma after curative resection

https://doi.org/10.18632/oncotarget.14530

Chu-Yu Jing, Yi-Peng Fu, Hu-Jia Shen, Su-Su Zheng, Jia-Jia Lin, Yong Yi, Jin-Long Huang, Xin Xu, Juan Zhang, Jian Zhou, Jia Fan, Zheng-Gang Ren, Shuang-Jian Qiu,  and Bo-Heng Zhang
13293-13303
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical outcome of tyrosine kinase inhibitors alone or combined with radiotherapy for brain metastases from epidermal growth factor receptor (EGFR) mutant non small cell lung cancer (NSCLC)

Clinical outcome of tyrosine kinase inhibitors alone or combined with radiotherapy for brain metastases from epidermal growth factor receptor (EGFR) mutant non small cell lung cancer (NSCLC)

https://doi.org/10.18632/oncotarget.14515

Qianqian Zhu, Yanan Sun, Yingying Cui, Ke Ye, Chengliang Yang, Daoke Yang, Jie Ma, Xiao Liu, Jinming Yu,  and Hong Ge
13304-13311
Abstract  |  PDF  |  HTML  |  Order a Reprint

Poly(C)-binding protein 1 mediates drug resistance in colorectal cancer

Poly(C)-binding protein 1 mediates drug resistance in colorectal cancer

https://doi.org/10.18632/oncotarget.14516

Jiani Guo, Changli Zhu, Kangqun Yang, Jin Li, Nan Du, Mingzhu Zong, Jianwei Zhou,  and Jingdong He
13312-13319
Abstract  |  PDF  |  HTML  |  Order a Reprint

Programmed cell death-ligand 1 expression predicts survival in patients with gastric carcinoma with microsatellite instability

Programmed cell death-ligand 1 expression predicts survival in patients with gastric carcinoma with microsatellite instability

https://doi.org/10.18632/oncotarget.14519

Junhun Cho, Jeeyun Lee, Heejin Bang, Seung Tae Kim, Se Hoon Park, Ji Yeong An, Min Gew Choi, Joon Ho Lee, Tae Sung Sohn, Jae Moon Bae, Won Ki Kang, Sung Kim,  and Kyoung-Mee Kim
13320-13328
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of long noncoding RNAs for the detection of early stage lung squamous cell carcinoma by microarray analysis

Identification of long noncoding RNAs for the detection of early stage lung squamous cell carcinoma by microarray analysis

https://doi.org/10.18632/oncotarget.14522

Zule Cheng, Yanan Bai, Ping Wang, Zhenhua Wu, Lin Zhou, Ming Zhong, Qinghui Jin, Jianlong Zhao, Hailei Mao,  and Hongju Mao
13329-13337
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pse-Analysis: a python package for DNA/RNA and protein/ peptide sequence analysis based on pseudo components and kernel methods

Pse-Analysis: a python package for DNA/RNA and protein/ peptide sequence analysis based on pseudo components and kernel methods

https://doi.org/10.18632/oncotarget.14524

Bin Liu, Hao Wu, Deyuan Zhang, Xiaolong Wang,  and Kuo-Chen Chou
13338-13343
Abstract  |  PDF  |  HTML  |  Order a Reprint

Pyruvate dehydrogenase expression is negatively associated with cell stemness and worse clinical outcome in prostate cancers

Pyruvate dehydrogenase expression is negatively associated with cell stemness and worse clinical outcome in prostate cancers

https://doi.org/10.18632/oncotarget.14527

Yali Zhong, Xiaoli Li, Yasai Ji, Xiaoran Li, Yaqing Li, Dandan Yu, Yuan Yuan, Jian Liu, Huixiang Li, Mingzhi Zhang, Zhenyu Ji, Dandan Fan, Jianguo Wen, Mariusz Adam Goscinski, Long Yuan, Bin Hao, Jahn M Nesland,  and Zhenhe Suo
13344-13356
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway

Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway

https://doi.org/10.18632/oncotarget.14528

Xiupeng Zhang, Guiyang Jiang, Mingfang Sun, Haijing Zhou, Yuan Miao, Mengyuan Liang, Enhua Wang,  and Yong Zhang
13357-13366
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Feasibility of abbreviated cycles of immunochemotherapy for completely resected limited-stage CD20+ diffuse large B-cell lymphoma (CISL 12-09)

Feasibility of abbreviated cycles of immunochemotherapy for completely resected limited-stage CD20+ diffuse large B-cell lymphoma (CISL 12-09)

https://doi.org/10.18632/oncotarget.14531

Dok Hyun Yoon, Byeong Seok Sohn, Sung Yong Oh, Won-Sik Lee, Sang Min Lee, Deok-Hwan Yang, Jooryung Huh,  and Cheolwon Suh
13367-13374
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification and characterization of HPV-independent cervical cancers

Identification and characterization of HPV-independent cervical cancers

https://doi.org/10.18632/oncotarget.14533

Carolyn E. Banister, Changlong Liu, Lucia Pirisi, Kim E. Creek,  and Phillip J. Buckhaults
13375-13386
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The diagnostic performance of shear wave speed (SWS) imaging for thyroid nodules with elasticity modulus and SWS measurement

The diagnostic performance of shear wave speed (SWS) imaging for thyroid nodules with elasticity modulus and SWS measurement

https://doi.org/10.18632/oncotarget.14534

Dan Wang, Ya-Ping He, Yi-Feng Zhang, Bo-Ji Liu, Chong-Ke Zhao, Hui-Jun Fu, Qing Wei,  and Hui-Xiong Xu
13387-13399
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic value of the pretreatment neutrophil-to-lymphocyte ratio in cervical cancer: a meta-analysis and systematic review

Prognostic value of the pretreatment neutrophil-to-lymphocyte ratio in cervical cancer: a meta-analysis and systematic review

https://doi.org/10.18632/oncotarget.14541

Jiayuan Wu, Manyu Chen, Caixia Liang,  and Wenmei Su
13400-13412
Abstract  |  PDF  |  HTML  |  Order a Reprint

Integrated proteomic and N-glycoproteomic analyses of doxorubicin sensitive and resistant ovarian cancer cells reveal glycoprotein alteration in protein abundance and glycosylation

Integrated proteomic and N-glycoproteomic analyses of doxorubicin sensitive and resistant ovarian cancer cells reveal glycoprotein alteration in protein abundance and glycosylation

https://doi.org/10.18632/oncotarget.14542

Yanlong Ji, Shasha Wei, Junjie Hou, Chengqian Zhang, Peng Xue, Jifeng Wang, Xiulan Chen, Xiaojing Guo,  and Fuquan Yang
13413-13427
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oxidative stress induced by Se-deficient high-energy diet implicates neutrophil dysfunction via Nrf2 pathway suppression in swine

Oxidative stress induced by Se-deficient high-energy diet implicates neutrophil dysfunction via Nrf2 pathway suppression in swine

https://doi.org/10.18632/oncotarget.14550

Tianshu Yang, Zeping Zhao, Tianqi Liu, Ziwei Zhang, Pengzu Wang, Shiwen Xu, Xin Gen Lei,  and Anshan Shan
13428-13439
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

National survey of China’s oncologists’ knowledge, attitudes, and clinical practice patterns on complementary and alternative medicine

National survey of China’s oncologists’ knowledge, attitudes, and clinical practice patterns on complementary and alternative medicine

https://doi.org/10.18632/oncotarget.14560

Geliang Yang, Richard Lee, Huiqing Zhang, Wei Gu, Peiying Yang,  and Changquan Ling
13440-13449
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-30c-5p ameliorates hepatic steatosis in leptin receptor-deficient (db/db) mice via down-regulating FASN

MiR-30c-5p ameliorates hepatic steatosis in leptin receptor-deficient (db/db) mice via down-regulating FASN

https://doi.org/10.18632/oncotarget.14561

Jiahui Fan, Huaping Li, Xiang Nie, Zhongwei Yin, Yanru Zhao, Chen Chen,  and Dao Wen Wang
13450-13463
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PDE5 inhibitors enhance the lethality of [pemetrexed + sorafenib]

PDE5 inhibitors enhance the lethality of [pemetrexed + sorafenib]

https://doi.org/10.18632/oncotarget.14562

Laurence Booth, Jane L. Roberts, Andrew Poklepovic,  and Paul Dent
13464-13475
Abstract  |  PDF  |  HTML  |  Order a Reprint

RYK promotes the stemness of glioblastoma cells via the WNT/ β-catenin pathway

RYK promotes the stemness of glioblastoma cells via the WNT/ β-catenin pathway

https://doi.org/10.18632/oncotarget.14564

Assunta Adamo, Danilo Fiore, Fabio De Martino, Giuseppina Roscigno, Alessandra Affinito, Elvira Donnarumma, Ilaria Puoti, Lucia Ricci Vitiani, Roberto Pallini, Cristina Quintavalle,  and Gerolama Condorelli
13476-13487
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Exploring the medication duration based on the effect of traditional Chinese medicine on postoperative stage I-III colorectal patients: a retrospective cohort study

Exploring the medication duration based on the effect of traditional Chinese medicine on postoperative stage I-III colorectal patients: a retrospective cohort study

https://doi.org/10.18632/oncotarget.14567

Qi Shi, Shanshan Liu, Wen Li, Shaoqi Zong, Susu Han, Wei Yang, Hongjia Li,  and Fenggang Hou
13488-13495
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Radioprotective effects of Keratinocyte Growth Factor-1 against irradiation-induced salivary gland hypofunction

Radioprotective effects of Keratinocyte Growth Factor-1 against irradiation-induced salivary gland hypofunction

https://doi.org/10.18632/oncotarget.14583

Jeong-Seok Choi, Hyun-Soo Shin, Hye-Young An, Young-Mo Kim,  and Jae-Yol Lim
13496-13508
Abstract  |  PDF  |  HTML  |  Order a Reprint

EZH2 inhibition suppresses endometrial cancer progression via miR-361/Twist axis

EZH2 inhibition suppresses endometrial cancer progression via miR-361/Twist axis

https://doi.org/10.18632/oncotarget.14586

Kei Ihira, Peixin Dong, Ying Xiong, Hidemichi Watari, Yosuke Konno, Sharon JB Hanley, Masayuki Noguchi, Noriyuki Hirata, Futoshi Suizu, Takahiro Yamada, Masataka Kudo,  and Noriaki Sakuragi
13509-13520
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HINT2 downregulation promotes colorectal carcinoma migration and metastasis

HINT2 downregulation promotes colorectal carcinoma migration and metastasis

https://doi.org/10.18632/oncotarget.14587

Weihua Li, Shaoxin Cai, Le Wang, Changshun Yang, Biaohuan Zhou,  and Huan Wang
13521-13531
Abstract  |  PDF  |  HTML  |  Order a Reprint

Gprc5a-knockout mouse lung epithelial cells predicts ceruloplasmin, lipocalin 2 and periostin as potential biomarkers at early stages of lung tumorigenesis

Gprc5a-knockout mouse lung epithelial cells predicts ceruloplasmin, lipocalin 2 and periostin as potential biomarkers at early stages of lung tumorigenesis

https://doi.org/10.18632/oncotarget.14589

Beibei Sun, Wenzheng Guo, Song Hu, Feng Yao, Keke Yu, Jie Xing, Ronghua Wang, Hongyong Song, Yueling Liao, Tong Wang, Pengfei Jiang, Baohui Han,  and Jiong Deng
13532-13544
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Intraperitoneal immunotherapy with T cells stably and transiently expressing anti-EpCAM CAR in xenograft models of peritoneal carcinomatosis

Intraperitoneal immunotherapy with T cells stably and transiently expressing anti-EpCAM CAR in xenograft models of peritoneal carcinomatosis

https://doi.org/10.18632/oncotarget.14592

Wei Xia Ang, Zhendong Li, Zhixia Chi, Shou-Hui Du, Can Chen, Johan C.K. Tay, Han Chong Toh, John E. Connolly, Xue Hu Xu,  and Shu Wang
13545-13559
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sinomenine hydrochloride inhibits breast cancer metastasis by attenuating inflammation-related epithelial-mesenchymal transition and cancer stemness

Sinomenine hydrochloride inhibits breast cancer metastasis by attenuating inflammation-related epithelial-mesenchymal transition and cancer stemness

https://doi.org/10.18632/oncotarget.14593

Xiao Li, Pingping Li, Chao Liu, Yu Ren, Xiaojiang Tang, Ke Wang,  and Jianjun He
13560-13574
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impact of NUDT15 polymorphisms on thiopurines-induced myelotoxicity and thiopurines tolerance dose

Impact of NUDT15 polymorphisms on thiopurines-induced myelotoxicity and thiopurines tolerance dose

https://doi.org/10.18632/oncotarget.14594

Dandan Yin, Xuyang Xia, Junlong Zhang, Shouyue Zhang, Fei Liao, Ge Zhang, Yan Zhang, Qianqian Hou, Xue Yang, Hong Wang, Zhigui Ma, Heyao Wang, Yiping Zhu, Wei Zhang, Yuelan Wang, Bo Liu, Lanlan Wang, Heng Xu,  and Yang Shu
13575-13585
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HnRNP-L mediates bladder cancer progression by inhibiting apoptotic signaling and enhancing MAPK signaling pathways

HnRNP-L mediates bladder cancer progression by inhibiting apoptotic signaling and enhancing MAPK signaling pathways

https://doi.org/10.18632/oncotarget.14600

Daojun Lv, Huayan Wu, Rongwei Xing, Fangpeng Shu, Bin Lei, Chengyong Lei, Xumin Zhou, Bo Wan, Yu Yang, Liren Zhong, Xiangming Mao,  and Yaguang Zou
13586-13599
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Telomerase antagonist imetelstat increases radiation sensitivity in esophageal squamous cell carcinoma

Telomerase antagonist imetelstat increases radiation sensitivity in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.14618

Xuping Wu, Jing Zhang, Sijun Yang, Zhihui Kuang, Guolei Tan, Gang Yang, Qichun Wei,  and Zhigang Guo
13600-13610
Abstract  |  PDF  |  HTML  |  Order a Reprint

Contribution of KRAS mutations and c.2369C > T (p.T790M) EGFR to acquired resistance to EGFR-TKIs in EGFR mutant NSCLC: a study on circulating tumor DNA

Contribution of KRAS mutations and c.2369C > T (p.T790M) EGFR to acquired resistance to EGFR-TKIs in EGFR mutant NSCLC: a study on circulating tumor DNA

https://doi.org/10.18632/oncotarget.6957

Marzia Del Re, Marcello Tiseo, Paola Bordi, Armida D’Incecco, Andrea Camerini, Iacopo Petrini, Maurizio Lucchesi, Alessandro Inno, Daniele Spada, Enrico Vasile, Valentina Citi, Giorgio Malpeli, Enrica Testa, Stefania Gori, Alfredo Falcone, Domenico Amoroso, Antonio Chella, Federico Cappuzzo, Andrea Ardizzoni, Aldo Scarpa,  and Romano Danesi
13611-13619
Abstract  |  PDF  |  HTML  |  Order a Reprint

Antitumor activity of a Trans-thiosemicarbazone schiff base palladium (II) complex on human gastric adenocarcinoma cells

Antitumor activity of a Trans-thiosemicarbazone schiff base palladium (II) complex on human gastric adenocarcinoma cells

https://doi.org/10.18632/oncotarget.14620

Bingchang Zhang, Haiqing Luo, Qinjuan Xu, Lirong Lin,  and Bing Zhang
13620-13631
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The pentapeptide Gly-Thr-Gly-Lys-Thr confers sensitivity to anti-cancer drugs by inhibition of CAGE binding to GSK3β and decreasing the expression of cyclinD1

The pentapeptide Gly-Thr-Gly-Lys-Thr confers sensitivity to anti-cancer drugs by inhibition of CAGE binding to GSK3β and decreasing the expression of cyclinD1

https://doi.org/10.18632/oncotarget.14621

Youngmi Kim, Hyuna Kim, Deokbum Park, Hansoo Lee, Yun Sil Lee, Jongseon Choe, Young Myeong Kim, Doyong Jeon,  and Dooil Jeoung
13632-13651
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Desirable cytolytic immune effector cell recruitment by interleukin-15 dendritic cells

Desirable cytolytic immune effector cell recruitment by interleukin-15 dendritic cells

https://doi.org/10.18632/oncotarget.14622

Heleen H. Van Acker, Ottavio Beretta, Sébastien Anguille, Lien De Caluwé, Angela Papagna, Johan M. Van den Bergh, Yannick Willemen, Herman Goossens, Zwi N. Berneman, Viggo F. Van Tendeloo, Evelien L. Smits, Maria Foti,  and Eva Lion
13652-13665
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-199a-5p and let-7c cooperatively inhibit migration and invasion by targeting MAP4K3 in hepatocellular carcinoma

MiR-199a-5p and let-7c cooperatively inhibit migration and invasion by targeting MAP4K3 in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.14623

Lili Liu, Liqin Lu, Aihong Zheng, Jiansheng Xie, Qian Xue, Fuwei Wang, Xiao Wang, Hongying Zhou, Xiangmin Tong, Yaqing Li, Xiuming Zhu,  and Guoqing Wu
13666-13677
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Down-regulation of toll-like receptor 4 alleviates intestinal ischemia reperfusion injury and acute lung injury in mice

Down-regulation of toll-like receptor 4 alleviates intestinal ischemia reperfusion injury and acute lung injury in mice

https://doi.org/10.18632/oncotarget.14624

Qiankun Zhu, Guizhen He, Jie Wang, Yukang Wang, Wei Chen,  and Tai Guo
13678-13689
Abstract  |  PDF  |  HTML  |  Order a Reprint

Long non-coding RNA growth arrest specific transcript 5 acts as a tumour suppressor in colorectal cancer by inhibiting interleukin-10 and vascular endothelial growth factor expression

Long non-coding RNA growth arrest specific transcript 5 acts as a tumour suppressor in colorectal cancer by inhibiting interleukin-10 and vascular endothelial growth factor expression

https://doi.org/10.18632/oncotarget.14625

Yuan Li, Yan Li, Shengkai Huang, Kun He, Mei Zhao, Hong Lin, Dongdong Li, Jiaming Qian, Caihong Zhou, Yuhua Chen,  and Changzhi Huang
13690-13702
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CTLA-4 positive breast cancer cells suppress dendritic cells maturation and function

CTLA-4 positive breast cancer cells suppress dendritic cells maturation and function

https://doi.org/10.18632/oncotarget.14626

Xi Chen, Qianqian Shao, Shengnan Hao, Zhonghua Zhao, Yang Wang, Xiaofan Guo, Ying He, Wenjuan Gao,  and Haiting Mao
13703-13715
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Cleavage of Fibulin-2 by the aggrecanases ADAMTS-4 and ADAMTS-5 contributes to the tumorigenic potential of breast cancer cells

Cleavage of Fibulin-2 by the aggrecanases ADAMTS-4 and ADAMTS-5 contributes to the tumorigenic potential of breast cancer cells

https://doi.org/10.18632/oncotarget.14627

Tania Fontanil, Saúl Álvarez-Teijeiro, M. Ángeles Villaronga, Yamina Mohamedi, Laura Solares, Angela Moncada-Pazos, José A. Vega, Olivia García-Suárez, Marcos Pérez-Basterrechea, Juana M. García-Pedrero, Alvaro J Obaya,  and Santiago Cal
13716-13729
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinically relevant HIF-1α-dependent metabolic reprogramming in oropharyngeal squamous cell carcinomas includes coordinated activation of CAIX and the miR-210/ISCU signaling axis, but not MCT1 and MCT4 upregulation

Clinically relevant HIF-1α-dependent metabolic reprogramming in oropharyngeal squamous cell carcinomas includes coordinated activation of CAIX and the miR-210/ISCU signaling axis, but not MCT1 and MCT4 upregulation

https://doi.org/10.18632/oncotarget.14629

Inés Sáenz-de-Santa-María, Cristóbal Bernardo-Castiñeira, Pablo Secades, Sandra Bernaldo-de-Quirós, Juan Pablo Rodrigo, Aurora Astudillo,  and María-Dolores Chiara
13730-13746
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association of T-cadherin levels with the response to neoadjuvant chemotherapy in locally advanced breast cancer

Association of T-cadherin levels with the response to neoadjuvant chemotherapy in locally advanced breast cancer

https://doi.org/10.18632/oncotarget.14630

Dedi Kong, Mei-Hong Wang, Jie Yang,  and Liang Li
13747-13753
Abstract  |  PDF  |  HTML  |  Order a Reprint

Autophagy-related gene LRRK2 is likely a susceptibility gene for systemic lupus erythematosus in northern Han Chinese

Autophagy-related gene LRRK2 is likely a susceptibility gene for systemic lupus erythematosus in northern Han Chinese

https://doi.org/10.18632/oncotarget.14631

Yue-miao Zhang, Xu-jie Zhou, Fa-juan Cheng, Yuan-yuan Qi, Ping Hou, Ming-hui Zhao,  and Hong Zhang
13754-13761
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic implications of intratumoral CD103+ tumor-infiltrating lymphocytes in pulmonary squamous cell carcinoma

Prognostic implications of intratumoral CD103+ tumor-infiltrating lymphocytes in pulmonary squamous cell carcinoma

https://doi.org/10.18632/oncotarget.14632

Jaemoon Koh, Sehui Kim, Moon-Young Kim, Heounjeong Go, Yoon Kyung Jeon,  and Doo Hyun Chung
13762-13769
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elimination of quiescent slow-cycling cells via reducing quiescence depth by natural compounds purified from Ganoderma lucidum

Elimination of quiescent slow-cycling cells via reducing quiescence depth by natural compounds purified from Ganoderma lucidum

https://doi.org/10.18632/oncotarget.14634

Jian Dai, Matthew A. Miller, Nicholas J. Everetts, Xia Wang, Peng Li, Ye Li, Jian-Hua Xu,  and Guang Yao
13770-13781
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Clinical impact of serum survivin positivity and tissue expression of EBV-encoded RNA in diffuse large B-cell lymphoma patients treated with rituximab–CHOP

Clinical impact of serum survivin positivity and tissue expression of EBV-encoded RNA in diffuse large B-cell lymphoma patients treated with rituximab–CHOP

https://doi.org/10.18632/oncotarget.14636

Jung Yong Hong, Kyung Ju Ryu, Chaehwa Park, Mineui Hong, Young Hyeh Ko, Won Seog Kim,  and Seok Jin Kim
13782-13791
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Priority Research Papers

The EMSY threonine 207 phospho-site is required for EMSYdriven suppression of DNA damage repair

The EMSY threonine 207 phospho-site is required for EMSYdriven suppression of DNA damage repair

https://doi.org/10.18632/oncotarget.14637

Petar Jelinic, Laura A. Eccles, Jill Tseng, Paulina Cybulska, Monicka Wielgos, Simon N. Powell,  and Douglas A. Levine
13792-13804
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Research Papers

Building personalized treatment plans for early-stage colorectal cancer patients

Building personalized treatment plans for early-stage colorectal cancer patients

https://doi.org/10.18632/oncotarget.14638

Hung-Hsin Lin, Nien-Chih Wei, Teh-Ying Chou, Chun-Chi Lin, Yuan-Tsu Lan, Shin-Ching Chang, Huann-Sheng Wang, Shung-Haur Yang, Wei- Shone Chen, Tzu-Chen Lin, Jen-Kou Lin,  and Jeng-Kai Jiang
13805-13817
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Vitamin K epoxide reductase regulation of androgen receptor activity

Vitamin K epoxide reductase regulation of androgen receptor activity

https://doi.org/10.18632/oncotarget.14639

Ben Yi Tew, Teresa B. Hong, Maya Otto-Duessel, Catherine Elix, Egbert Castro, Miaoling He, Xiwei Wu, Sumanta K. Pal, Markus Kalkum,  and Jeremy O. Jones
13818-13831
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metformin promotes apoptosis in hepatocellular carcinoma through the CEBPD-induced autophagy pathway

Metformin promotes apoptosis in hepatocellular carcinoma through the CEBPD-induced autophagy pathway

https://doi.org/10.18632/oncotarget.14640

Hsin-Hwa Tsai, Hong-Yue Lai, Yueh-Chiu Chen, Chien-Feng Li, Huei-Sheng Huang, Hsiao-Sheng Liu, Yau-Sheng Tsai,  and Ju-Ming Wang
13832-13845
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PAFR selectively mediates radioresistance and irradiation-induced autophagy suppression in prostate cancer cells

PAFR selectively mediates radioresistance and irradiation-induced autophagy suppression in prostate cancer cells

https://doi.org/10.18632/oncotarget.14647

Bing Yao, Bingqian Liu, Lei Shi, Xiang Li, Chuanchuan Ren, Mingbo Cai, Wen Wang, Jianhua Li, Yongde Sun, Yudong Wu,  and Jianguo Wen
13846-13854
Abstract  |  PDF  |  HTML  |  Order a Reprint

BI-RADS 3–5 microcalcifications can preoperatively predict breast cancer HER2 and Luminal a molecular subtype

BI-RADS 3–5 microcalcifications can preoperatively predict breast cancer HER2 and Luminal a molecular subtype

https://doi.org/10.18632/oncotarget.14655

DongZhi Cen, Li Xu, Ningna Li, Zhiguang Chen, Lu Wang, Shuqin Zhou, Biao Xu, Chun ling Liu, Zaiyi Liu,  and Tingting Luo
13855-13862
Abstract  |  PDF  |  HTML  |  Order a Reprint

Significant association between Let-7-KRAS rs712 G > T polymorphism and cancer risk in the Chinese population: a meta-analysis

Significant association between Let-7-KRAS rs712 G > T polymorphism and cancer risk in the Chinese population: a meta-analysis

https://doi.org/10.18632/oncotarget.14672

Xin-Ya Du, Yuan-Yuan Hu, Chun Xie, Chun-Yan Deng, Cai-Yun Liu, Zhi-Guo Luo, Yu-Ming Niu,  and Ming Shen
13863-13871
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-140 mediates RB tumor suppressor function to control stem cell-like activity through interleukin-6

MicroRNA-140 mediates RB tumor suppressor function to control stem cell-like activity through interleukin-6

https://doi.org/10.18632/oncotarget.14681

Akiyo Yoshida, Shunsuke Kitajima, Fengkai Li, Chaoyang Cheng, Yujiro Takegami, Susumu Kohno, Yuan Song Wan, Naoyuki Hayashi, Hayato Muranaka, Yuuki Nishimoto, Naoko Nagatani, Takumi Nishiuchi, Tran C Thai, Sawako Suzuki, Shinji Nakao, Tomoaki Tanaka, Osamu Hirose, David A. Barbie,  and Chiaki Takahashi
13872-13885
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Loss of endothelial cell-specific molecule 1 promotes the tumorigenicity and metastasis of prostate cancer cells through regulation of the TIMP-1/MMP-9 expression

Loss of endothelial cell-specific molecule 1 promotes the tumorigenicity and metastasis of prostate cancer cells through regulation of the TIMP-1/MMP-9 expression

https://doi.org/10.18632/oncotarget.14684

Chien-Min Chen, Chu-Liang Lin, Hui-Ling Chiou, Shu-Ching Hsieh, Chia-Liang Lin, Chun-Wen Cheng, Chia-Hung Hung, Jen-Pi Tsai,  and Yi-Hsien Hsieh
13886-13897
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FAK regulates E-cadherin expression via p-SrcY416/p-ERK1/2/p-Stat3Y705 and PPARγ/miR-125b/Stat3 signaling pathway in B16F10 melanoma cells

FAK regulates E-cadherin expression via p-SrcY416/p-ERK1/2/p-Stat3Y705 and PPARγ/miR-125b/Stat3 signaling pathway in B16F10 melanoma cells

https://doi.org/10.18632/oncotarget.14687

Guoshun Pei, Yan Lan, Dianhua Chen, Lina Ji,  and Zi-chun Hua
13898-13908
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Systematic analysis of molecular mechanisms for HCC metastasis via text mining approach

Systematic analysis of molecular mechanisms for HCC metastasis via text mining approach

https://doi.org/10.18632/oncotarget.14692

Cheng Zhen, Caizhong Zhu, Haoyang Chen, Yiru Xiong, Junyuan Tan, Dong Chen,  and Jin Li
13909-13916
Abstract  |  PDF  |  HTML  |  Order a Reprint

Wilms’ tumor gene 1 silencing inhibits proliferation of human osteosarcoma MG-63 cell line by cell cycle arrest and apoptosis activation

Wilms’ tumor gene 1 silencing inhibits proliferation of human osteosarcoma MG-63 cell line by cell cycle arrest and apoptosis activation

https://doi.org/10.18632/oncotarget.14715

Adriana Carol Eleonora Graziano, Venera Cardile, Rosanna Avola, Nunzio Vicario, Carmela Parenti, Lucia Salvatorelli, Gaetano Magro,  and Rosalba Parenti
13917-13931
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Increased breast cancer risk with HABP1/p32/gC1qR genetic polymorphism rs2285747 and its upregulation in northern Chinese women

Increased breast cancer risk with HABP1/p32/gC1qR genetic polymorphism rs2285747 and its upregulation in northern Chinese women

https://doi.org/10.18632/oncotarget.14737

Yongdong Jiang, Hao Wu, Jing Liu, Yanbo Chen, Jingjing Xie, Yashuang Zhao,  and Da Pang
13932-13941
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Repurposing an antidandruff agent to treating cancer: zinc pyrithione inhibits tumor growth via targeting proteasome-associated deubiquitinases

Repurposing an antidandruff agent to treating cancer: zinc pyrithione inhibits tumor growth via targeting proteasome-associated deubiquitinases

https://doi.org/10.18632/oncotarget.14572

Chong Zhao, Xin Chen, Changshan Yang, Dan Zang, Xiaoying Lan, Siyan Liao, Peiquan Zhang, Jinjie Wu, Xiaofen Li, Ningning Liu, Yuning Liao, Hongbiao Huang, Xianping Shi, Lili Jiang, Xiuhua Liu, Q. Ping Dou, Xuejun Wang,  and Jinbao Liu
13942-13956
Abstract  |  PDF  |  HTML  |  Order a Reprint

Sensitization of glycoengineered interferon-β1a-resistant cancer cells by cFLIP inhibition for enhanced anti-cancer therapy

Sensitization of glycoengineered interferon-β1a-resistant cancer cells by cFLIP inhibition for enhanced anti-cancer therapy

https://doi.org/10.18632/oncotarget.14573

Tae-Eun Kim, Sungyoul Hong, Kyoung Song, Sang-Ho Park,  and Young Kee Shin
13957-13970
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel long noncoding RNA PILRLS promote proliferation through TCL1A by activing MDM2 in Retroperitoneal liposarcoma

A novel long noncoding RNA PILRLS promote proliferation through TCL1A by activing MDM2 in Retroperitoneal liposarcoma

https://doi.org/10.18632/oncotarget.14814

Yebo Shao, Yong Zhang, Yingyong Hou, Hanxing Tong, Rongyuan Zhuang, Zhengbiao Ji, Binliang Wang, Yuhong Zhou,  and Weiqi Lu
13971-13978
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic and predictive value of VHL gene alteration in renal cell carcinoma: a meta-analysis and review

Prognostic and predictive value of VHL gene alteration in renal cell carcinoma: a meta-analysis and review

https://doi.org/10.18632/oncotarget.14704

Bum Jun Kim, Jung Han Kim, Hyeong Su Kim,  and Dae Young Zang
13979-13985
Abstract  |  PDF  |  HTML  |  Order a Reprint

Protein S drives oral squamous cell carcinoma tumorigenicity through regulation of AXL

Protein S drives oral squamous cell carcinoma tumorigenicity through regulation of AXL

https://doi.org/10.18632/oncotarget.14753

Ghada Abboud-Jarrous, Shivam Priya, Avi Maimon, Stuart Fischman, Mayan Cohen-Elisha, Rakefet Czerninski,  and Tal Burstyn-Cohen
13986-14002
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genome-wide screen identifies a novel prognostic signature for breast cancer survival

Genome-wide screen identifies a novel prognostic signature for breast cancer survival

https://doi.org/10.18632/oncotarget.14776

Xuan Y. Mao, Matthew J. Lee, Jeffrey Zhu, Carissa Zhu, Sindy M. Law,  and Antoine M. Snijders
14003-14016
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dual inhibition of histone deacetylases and phosphoinositide 3-kinase enhances therapeutic activity against B cell lymphoma

Dual inhibition of histone deacetylases and phosphoinositide 3-kinase enhances therapeutic activity against B cell lymphoma

https://doi.org/10.18632/oncotarget.14876

Patrizia Mondello, Enrico Derenzini, Zahra Asgari, John Philip, Elliott J. Brea, Venkatraman Seshan, Ronald C. Hendrickson, Elisa de Stanchina, David A. Scheinberg,  and Anas Younes
14017-14028
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Concurrent chemoradiotherapy degrades the quality of life of patients with stage II nasopharyngeal carcinoma as compared to radiotherapy

Concurrent chemoradiotherapy degrades the quality of life of patients with stage II nasopharyngeal carcinoma as compared to radiotherapy

https://doi.org/10.18632/oncotarget.14932

Xin-Bin Pan, Shi-Ting Huang, Kai-Hua Chen, Yan-Ming Jiang, Jia-Lin Ma, Song Qu, Ling Li, Long Chen,  and Xiao-Dong Zhu
14029-14038
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical Research Papers

Prostatic vascular damage induced by cigarette smoking as a risk factor for recovery after holmium laser enucleation of the prostate (HoLEP)

Prostatic vascular damage induced by cigarette smoking as a risk factor for recovery after holmium laser enucleation of the prostate (HoLEP)

https://doi.org/10.18632/oncotarget.12538

Huan Xu, Chong Liu, Meng Gu, Yanbo Chen, Zhikang Cai, Qi Chen,  and Zhong Wang
14039-14049
Abstract  |  PDF  |  HTML  |  Order a Reprint

Pre-treatment assay of 5-fluorouracil degradation rate (5-FUDR) to improve prediction of 5-fluorouracil toxicity in gastro-esophageal cancer

Pre-treatment assay of 5-fluorouracil degradation rate (5-FUDR) to improve prediction of 5-fluorouracil toxicity in gastro-esophageal cancer

https://doi.org/10.18632/oncotarget.12571

Marina Borro, Andrea Botticelli, Federica Mazzuca, Elisa Concetta Onesti, Giovanna Gentile, Adriana Romiti, Bruna Cerbelli, Eva Mazzotti, Luca Marchetti, Luana Lionetto, Maurizio Simmaco,  and Paolo Marchetti
14050-14057
Abstract  |  PDF  |  HTML  |  Order a Reprint

A novel grade-lymph node ratio model predicts the prognosis of the advanced gastric cancer patients after neoadjuvant radiotherapy

A novel grade-lymph node ratio model predicts the prognosis of the advanced gastric cancer patients after neoadjuvant radiotherapy

https://doi.org/10.18632/oncotarget.12573

Jianjun Liu, Mingxue Su, Jing Wang, Gan Zhang, Jing Zhou, Anqing Zhang, Zixue Ren, Xucai Zheng, Shikai Hong, Shengying Wang,  and Rongxin Zhang
14058-14067
Abstract  |  PDF  |  HTML  |  Order a Reprint

Intensity-modulated radiation therapy achieves better local control compared to three-dimensional conformal radiation therapy for T4-stage nasopharyngeal carcinoma

Intensity-modulated radiation therapy achieves better local control compared to three-dimensional conformal radiation therapy for T4-stage nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.12736

Jenny Ling-Yu Chen, Yu-Sen Huang, Sung-Hsin Kuo, Ruey-Long Hong, Jenq-Yuh Ko, Pei-Jen Lou,  and Chun-Wei Wang
14068-14077
Abstract  |  PDF  |  HTML  |  Order a Reprint

Matched analysis of induction chemotherapy plus chemoradiotherapy versus induction chemotherapy plus radiotherapy alone in locoregionally advanced nasopharyngeal carcinoma: a multicenter study

Matched analysis of induction chemotherapy plus chemoradiotherapy versus induction chemotherapy plus radiotherapy alone in locoregionally advanced nasopharyngeal carcinoma: a multicenter study

https://doi.org/10.18632/oncotarget.13285

Bin Zhang, Ying Hu, Rui-Hua Xiong, Yu-Fei Pan, Qian-Lan Xu, Xiang-Yun Kong, Rui Cai, Qiu-Qiu Chen, Hua-Ying Tang,  and Wei Jiang
14078-14088
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

The crosstalk between microRNAs and the Wnt/β-catenin signaling pathway in cancer

The crosstalk between microRNAs and the Wnt/β-catenin signaling pathway in cancer

https://doi.org/10.18632/oncotarget.12923

Yin Peng, Xiaojing Zhang, Xianling Feng, Xinmim Fan,  and Zhe Jin
14089-14106
Abstract  |  PDF  |  HTML  |  Order a Reprint

Different imaging techniques for the detection of pelvic lymph nodes metastasis from gynecological malignancies: a systematic review and meta-analysis

Different imaging techniques for the detection of pelvic lymph nodes metastasis from gynecological malignancies: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.12959

Yi Gong, Qingming Wang, Li Dong, Yiping Jia, Chengge Hua, Fanglin Mi,  and Chunjie Li
14107-14125
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

­Long noncoding RNA HOTTIP as a novel predictor of lymph node metastasis and survival in human cancer: a systematic review and meta-analysis

­Long noncoding RNA HOTTIP as a novel predictor of lymph node metastasis and survival in human cancer: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.12981

Zhicong Chen, Anbang He, Dailian Wang, Yuchen Liu,  and Weiren Huang
14126-14132
Abstract  |  PDF  |  HTML  |  Order a Reprint

Warburg effect, hexokinase-II, and radioresistance of laryngeal carcinoma

Warburg effect, hexokinase-II, and radioresistance of laryngeal carcinoma

https://doi.org/10.18632/oncotarget.13044

Jiang-Tao Zhong,  and Shui-Hong Zhou
14133-14146
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cell membrane-anchored MUC4 promotes tumorigenicity in epithelial carcinomas

Cell membrane-anchored MUC4 promotes tumorigenicity in epithelial carcinomas

https://doi.org/10.18632/oncotarget.13122

Pengpeng Xia, Agnes Hakyung Choi, Zengping Deng, Yuqian Yang, Jing Zhao, Yiting Wang, Philip R. Hardwidge,  and Guoqiang Zhu
14147-14157
Abstract  |  PDF  |  HTML  |  Order a Reprint

Unveiling changes in the landscape of patient populations in cancer early drug development

Unveiling changes in the landscape of patient populations in cancer early drug development

https://doi.org/10.18632/oncotarget.13258

Cinta Hierro, Analía Azaro, Guillem Argilés, Elena Elez, Patricia Gómez, Joan Carles,  and Jordi Rodon
14158-14172
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Deciphering the link between PI3K and PAK: An opportunity to target key pathways in pancreatic cancer?

Deciphering the link between PI3K and PAK: An opportunity to target key pathways in pancreatic cancer?

https://doi.org/10.18632/oncotarget.13309

Kiruthikah Thillai, Hoyin Lam, Debashis Sarker,  and Claire M. Wells
14173-14191
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Serum and tissue markers in hepatocellular carcinoma and cholangiocarcinoma: clinical and prognostic implications

Serum and tissue markers in hepatocellular carcinoma and cholangiocarcinoma: clinical and prognostic implications

https://doi.org/10.18632/oncotarget.13929

Massimiliano Berretta, Carla Cavaliere, Lara Alessandrini, Brigida Stanzione, Gaetano Facchini, Luca Balestreri, Tiziana Perin,  and Vincenzo Canzonieri
14192-14220
Abstract  |  PDF  |  HTML  |  Order a Reprint

Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells

Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells

https://doi.org/10.18632/oncotarget.13991

James A. McCubrey, Timothy L. Fitzgerald, Li V. Yang, Kvin Lertpiriyapong, Linda S. Steelman, Stephen L. Abrams, Giuseppe Montalto, Melchiorre Cervello, Luca M. Neri, Lucio Cocco, Alberto M. Martelli, Piotr Laidler, Joanna Dulińska-Litewka, Dariusz Rakus, Agnieszka Gizak, Ferdinando Nicoletti, Luca Falzone, Saverio Candido,  and Massimo Libra
14221-14250
Abstract  |  PDF  |  HTML  |  Order a Reprint

Metabolic enzymes: key modulators of functionality in cancer stem-like cells

Metabolic enzymes: key modulators of functionality in cancer stem-like cells

https://doi.org/10.18632/oncotarget.14041

Bo-Wen Dong, Guang-Ming Qin, Yan Luo,  and Jian-Shan Mao
14251-14267
Abstract  |  PDF  |  HTML  |  Order a Reprint

Corrections

Correction: Dehydroandrographolide, an iNOS inhibitor, extracted from Andrographis paniculata (Burm.f.) Nees, induces autophagy in human oral cancer cells

Correction: Dehydroandrographolide, an iNOS inhibitor, extracted from Andrographis paniculata (Burm.f.) Nees, induces autophagy in human oral cancer cells

https://doi.org/10.18632/oncotarget.15541

Ming-Ju Hsieh, Chiao-Wen Lin, Hui-Ling Chiou, Shun-Fa Yang,  and Mu-Kuan Chen
14268-14268
Correction  |  PDF


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