Oncotarget

Vol 8, No 7

February 14, 2017

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About The Cover

The cover for issue 7 of Oncotarget features Optimal in vitro activation of innate immunity to antigen-drive unfractionated human peripheral blood mononuclear cells (PBMC) from Pathangey, et al.

Table of Contents

News

Glutaminolysis gets the spotlight in cancer

Glutaminolysis gets the spotlight in cancer

https://doi.org/10.18632/oncotarget.14384

Daniel Herranz
10761-10762
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Allelic imbalance in human breast cancer

Allelic imbalance in human breast cancer

https://doi.org/10.18632/oncotarget.14648

Juliet D. French,  and Stacey L. Edwards
10763-10764
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Uncovering the role of USP54 in cancer

Uncovering the role of USP54 in cancer

https://doi.org/10.18632/oncotarget.14820

Veronica Miguela,  and Amaia Lujambio
10765-10766
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The making of a killer (T cell)

The making of a killer (T cell)

https://doi.org/10.18632/oncotarget.15229

Willem W. Overwijk
10767-10768
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Editorial

microRNA-494 and ATF3 the targets of onconase(?)

microRNA-494 and ATF3 the targets of onconase(?)

https://doi.org/10.18632/oncotarget.13799

Zbigniew Darzynkiewicz
10769-10770
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Editorial: Neuroscience

Versatile use of rtTA-expressing retroviruses in the study of neurodegeneration

Versatile use of rtTA-expressing retroviruses in the study of neurodegeneration

https://doi.org/10.18632/oncotarget.14386

Catia M. Teixeira, Jesús Ávila,  and María Llorens-Martín
10771-10772
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The Tat-Aβ1-6A2V(D) peptide against AD synaptopathy

The Tat-Aβ1-6A2V(D) peptide against AD synaptopathy

https://doi.org/10.18632/oncotarget.14604

Lucia Buccarello,  and Tiziana Borsello
10773-10774
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Role of VEGF-A in chronic pain

Role of VEGF-A in chronic pain

https://doi.org/10.18632/oncotarget.14615

Richard P. Hulse
10775-10776
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Oxidative stress in neurodegenerative disease: causation or association?

Oxidative stress in neurodegenerative disease: causation or association?

https://doi.org/10.18632/oncotarget.14650

Jeremy M. Van Raamsdonk, Irving E. Vega,  and Patrik Brundin
10777-10778
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Functional sites for anesthetics in GABAA receptors

Functional sites for anesthetics in GABAA receptors

https://doi.org/10.18632/oncotarget.14616

Maria C. Maldifassi,  and Erwin Sigel
10779-10780
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Imaging of MSC transplantation in neuroscience

Imaging of MSC transplantation in neuroscience

https://doi.org/10.18632/oncotarget.14643

Miriam Filippi, Marina Boido,  and Enzo Terreno
10781-10782
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Dissecting stress with transcriptomics

Dissecting stress with transcriptomics

https://doi.org/10.18632/oncotarget.14693

Mattia Privitera, Amalia Floriou-Servou,  and Johannes Bohacek
10783-10784
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Priority Research Papers

Surrogate in vitro activation of innate immunity synergizes with interleukin-7 to unleash rapid antigen-driven outgrowth of CD4+ and CD8+ human peripheral blood T-cells naturally recognizing MUC1, HER2/neu and other tumor-associated antigens

Surrogate in vitro activation of innate immunity synergizes with interleukin-7 to unleash rapid antigen-driven outgrowth of CD4+ and CD8+ human peripheral blood T-cells naturally recognizing MUC1, HER2/neu and other tumor-associated antigens

https://doi.org/10.18632/oncotarget.13911

Latha B. Pathangey, Dustin B. McCurry, Sandra J. Gendler, Ana L. Dominguez, Jessica E. Gorman, Girish Pathangey, Laurie A. Mihalik, Yushe Dang, Mary L. Disis,  and Peter A. Cohen
10785-10808
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Gadd45a deficiency accelerates BCR-ABL driven chronic myelogenous leukemia

Gadd45a deficiency accelerates BCR-ABL driven chronic myelogenous leukemia

https://doi.org/10.18632/oncotarget.14580

Kaushiki Mukherjee, VXiaojin Sha, Andrew Magimaidas, Silvia Maifrede, Tomasz Skorski, Ravi Bhatia, Barbara Hoffman,  and Dan A. Liebermann
10809-10821
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Research Papers: Pathology

Bradykinin regulates cell growth and migration in cultured human cardiac c-Kit+ progenitor cells

Bradykinin regulates cell growth and migration in cultured human cardiac c-Kit+ progenitor cells

https://doi.org/10.18632/oncotarget.14609

Gang Li, Yan Wang,  and Gui-Rong Li
10822-10835
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Test anxiety and telomere length: Academic stress in adolescents may not cause rapid telomere erosion

Test anxiety and telomere length: Academic stress in adolescents may not cause rapid telomere erosion

https://doi.org/10.18632/oncotarget.14793

Yaru Zou, Waiian Leong, Mingling Yao, Xuefei Hu, Sixiao Lu, Xiaowei Zhu, Lianxiang Chen, Jianjing Tong, Jingyi Shi, Eric Gilson, Jing Ye,  and Yiming Lu
10836-10844
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Genome-wide copy number aberrations and HER2 and FGFR1 alterations in primary breast cancer by molecular inversion probe microarray

Genome-wide copy number aberrations and HER2 and FGFR1 alterations in primary breast cancer by molecular inversion probe microarray

https://doi.org/10.18632/oncotarget.14802

Hui Chen, Rajesh R. Singh, Xinyan Lu, Lei Huo, Hui Yao, Kenneth Aldape, Ronald Abraham, Shumaila Virani, Meenakshi Mehrotra, Bal Mukund Mishra, Alex Bousamra, Constance Albarracin, Yun Wu, Sinchita Roy-Chowdhuri, Rashmi Kanagal Shamanna, Mark J. Routbort, L. Jeffrey Medeiros, Keyur P. Patel, Russell Broaddus, Aysegul Sahin,  and Rajyalakshmi Luthra
10845-10857
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Research Papers: Immunology

A prospective birth cohort study of different risk factors for development of allergic diseases in offspring of non-atopic parents

A prospective birth cohort study of different risk factors for development of allergic diseases in offspring of non-atopic parents

https://doi.org/10.18632/oncotarget.14565

Ming-Tsung Lee, Chih-Chiang Wu, Chia-Yu Ou, Jen-Chieh Chang, Chieh-An Liu, Chih-Lu Wang, Hau Chuang, Ho-Chang Kuo, Te-Yao Hsu, Chie-Pein Chen,  and Kuender D. Yang
10858-10870
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Meta-analysis of the actions of antithymocyte globulin in patients undergoing allogeneic hematopoietic cell transplantation

Meta-analysis of the actions of antithymocyte globulin in patients undergoing allogeneic hematopoietic cell transplantation

https://doi.org/10.18632/oncotarget.14719

Jiaojiao Yuan, Renzhi Pei, Wensi Su, Junjie Cao,  and Ying Lu
10871-10882
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Research Papers

The cornucopia of meaningful leads: Applying deep adversarial autoencoders for new molecule development in oncology

The cornucopia of meaningful leads: Applying deep adversarial autoencoders for new molecule development in oncology

https://doi.org/10.18632/oncotarget.14073

Artur Kadurin, Alexander Aliper, Andrey Kazennov, Polina Mamoshina, Quentin Vanhaelen, Kuzma Khrabrov,  and Alex Zhavoronkov
10883-10890
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Gedunin inhibits pancreatic cancer by altering sonic hedgehog signaling pathway

Gedunin inhibits pancreatic cancer by altering sonic hedgehog signaling pathway

https://doi.org/10.18632/oncotarget.8055

Ramadevi Subramani, Elizabeth Gonzalez, Sushmita Bose Nandy, Arunkumar Arumugam, Fernando Camacho, Joshua Medel, Damilola Alabi,  and Rajkumar Lakshmanaswamy
10891-10904
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Drug-dependent functionalization of wild-type and mutant p53 in cisplatin-resistant human ovarian tumor cells

Drug-dependent functionalization of wild-type and mutant p53 in cisplatin-resistant human ovarian tumor cells

https://doi.org/10.18632/oncotarget.14228

Michelle Bhatt, Cristina Ivan, Xiaolei Xie,  and Zahid H. Siddik
10905-10918
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Full preclinical validation of the 123I-labeled anti-PSMA antibody fragment ScFvD2B for prostate cancer imaging

Full preclinical validation of the 123I-labeled anti-PSMA antibody fragment ScFvD2B for prostate cancer imaging

https://doi.org/10.18632/oncotarget.14229

Barbara Frigerio, Gerben Franssen, Elena Luison, Alessandro Satta, Ettore Seregni, Marco Colombatti, Giulio Fracasso, Riccardo Valdagni, Delia Mezzanzanica, Otto Boerman, Silvana Canevari,  and Mariangela Figini
10919-10930
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FLT3 activating mutations display differential sensitivity to multiple tyrosine kinase inhibitors

FLT3 activating mutations display differential sensitivity to multiple tyrosine kinase inhibitors

https://doi.org/10.18632/oncotarget.14539

Bao Nguyen, Allen B. Williams, David J. Young, Hayley Ma, Li Li, Mark Levis, Patrick Brown,  and Donald Small
10931-10944
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Modeling the phenotype of spinal muscular atrophy by the direct conversion of human fibroblasts to motor neurons

Modeling the phenotype of spinal muscular atrophy by the direct conversion of human fibroblasts to motor neurons

https://doi.org/10.18632/oncotarget.14641

Qi-Jie Zhang, Jin-Jing Li, Xiang Lin, Ying-Qian Lu, Xin-Xin Guo, En-Lin Dong, Miao Zhao, Jin He, Ning Wang,  and Wan-Jin Chen
10945-10953
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A neutralized human LMP1-IgG inhibits ENKTL growth by suppressing the JAK3/STAT3 signaling pathway

A neutralized human LMP1-IgG inhibits ENKTL growth by suppressing the JAK3/STAT3 signaling pathway

https://doi.org/10.18632/oncotarget.14032

Yuan Mao, Jun Wang, Mingzhi Zhang, Weifei Fan, Qi Tang, Siping Xiong, Xiaojun Tang, Juqing Xu, Lin Wang, Shu Yang, Suyao Liu, Li Xu, Yan Chen, Lin Xu, Rong Yin,  and Jin Zhu
10954-10965
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Combined inhibition of Wee1 and Chk1 gives synergistic DNA damage in S-phase due to distinct regulation of CDK activity and CDC45 loading

Combined inhibition of Wee1 and Chk1 gives synergistic DNA damage in S-phase due to distinct regulation of CDK activity and CDC45 loading

https://doi.org/10.18632/oncotarget.14089

Sissel Hauge, Christian Naucke, Grete Hasvold, Mrinal Joel, Gro Elise Rødland, Petras Juzenas, Trond Stokke,  and Randi G. Syljuåsen
10966-10979
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The role of miR-17-92 in the miRegulatory landscape of Ewing sarcoma

The role of miR-17-92 in the miRegulatory landscape of Ewing sarcoma

https://doi.org/10.18632/oncotarget.14091

Raphaela Schwentner, David Herrero-Martin, Maximilian O Kauer, Cornelia N Mutz, Anna M Katschnig, Grzegorz Sienski, Javier Alonso, Dave NT Aryee,  and Heinrich Kovar
10980-10993
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preoperative serum levels of insulin-like growth factor-binding protein 2 predict prognosis of gastric cancer patients

Preoperative serum levels of insulin-like growth factor-binding protein 2 predict prognosis of gastric cancer patients

https://doi.org/10.18632/oncotarget.14202

Hoon Hur, Eun Ji Yu, In-Hye Ham, Hye-Jin Jin,  and Dakeun Lee
10994-11003
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UV-induced proteolysis of RNA polymerase II is mediated by VCP/p97 segregase and timely orchestration by Cockayne syndrome B protein

UV-induced proteolysis of RNA polymerase II is mediated by VCP/p97 segregase and timely orchestration by Cockayne syndrome B protein

https://doi.org/10.18632/oncotarget.14205

Jinshan He, Qianzheng Zhu, Gulzar Wani,  and Altaf A. Wani
11004-11019
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preclinical efficacy of Sym004, novel anti-EGFR antibody mixture, in esophageal squamous cell carcinoma cell lines

Preclinical efficacy of Sym004, novel anti-EGFR antibody mixture, in esophageal squamous cell carcinoma cell lines

https://doi.org/10.18632/oncotarget.14209

Shota Fukuoka, Takashi Kojima, Yoshikatsu Koga, Mayumi Yamauchi, Masayuki Komatsu, Rie Komatsuzaki, Hiroki Sasaki, Masahiro Yasunaga, Yasuhiro Matsumura, Toshihiko Doi,  and Atsushi Ohtsu
11020-11029
Abstract  |  PDF  |  HTML  |  Order a Reprint

Chromosome nondisjunction during bipolar mitoses of binucleated intermediates promote aneuploidy formation along with multipolar mitoses rather than chromosome loss in micronuclei induced by asbestos

Chromosome nondisjunction during bipolar mitoses of binucleated intermediates promote aneuploidy formation along with multipolar mitoses rather than chromosome loss in micronuclei induced by asbestos

https://doi.org/10.18632/oncotarget.14212

Tianwei Zhang, Lei Lv, Yun Huang, Xiaohui Ren,  and Qinghua Shi
11030-11041
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mcl-1 expression and JNK activation induces a threshold for apoptosis in Bcl-xL-overexpressing hematopoietic cells

Mcl-1 expression and JNK activation induces a threshold for apoptosis in Bcl-xL-overexpressing hematopoietic cells

https://doi.org/10.18632/oncotarget.14223

Yu Zhang, Xin Li, Shisheng Tan, Xinyu Liu, Xinyu Zhao, Zhu Yuan,  and Chunlai Nie
11042-11052
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Otub1 stabilizes MDMX and promotes its proapoptotic function at the mitochondria

Otub1 stabilizes MDMX and promotes its proapoptotic function at the mitochondria

https://doi.org/10.18632/oncotarget.14278

Yingxiao Chen, Yue-Gang Wang, Yuhuang Li, Xiao-Xin Sun,  and Mu-Shui Dai
11053-11062
Abstract  |  PDF  |  HTML  |  Order a Reprint

Serum hepatitis B core antibody titer use in screening for significant fibrosis in treatment-naïve patients with chronic hepatitis B

Serum hepatitis B core antibody titer use in screening for significant fibrosis in treatment-naïve patients with chronic hepatitis B

https://doi.org/10.18632/oncotarget.14323

Min-ran Li, Huan-wei Zheng, Jian-hua Lu, Shun-mao Ma, Li-hong Ye, Zhi-quan Liu, Hai-cong Zhang, Yun-yan Liu, Ying Lv, Yan Huang, Er-hei Dai,  and Dian-xing Sun
11063-11070
Abstract  |  PDF  |  HTML  |  Order a Reprint

miR-138-5p suppresses autophagy in pancreatic cancer by targeting SIRT1

miR-138-5p suppresses autophagy in pancreatic cancer by targeting SIRT1

https://doi.org/10.18632/oncotarget.14360

She Tian, Xingjun Guo, Chao Yu, Chengyi Sun,  and Jianxin Jiang
11071-11082
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Molecular differences between cerebral blood volume and vessel size in glioblastoma multiforme

Molecular differences between cerebral blood volume and vessel size in glioblastoma multiforme

https://doi.org/10.18632/oncotarget.11522

Dieter Henrik Heiland, Theo Demerath, Elias Kellner, Valerij G. Kiselev, Dietmar Pfeifer, Oliver Schnell, Ori Staszewski, Horst Urbach, Astrid Weyerbrock,  and Irina Mader
11083-11093
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Direct analysis of aberrant glycosylation on haptoglobin in patients with gastric cancer

Direct analysis of aberrant glycosylation on haptoglobin in patients with gastric cancer

https://doi.org/10.18632/oncotarget.14362

Jae-Han Kim, Sung Hyeon Lee, Sookyung Choi, Unyong Kim, In Seok Yeo, Su Hee Kim, Myung Jin Oh, Hantae Moon, Jua Lee, Seunghyup Jeong, Min Gew Choi, Jun Ho Lee, Tae Sung Sohn, Jae Moon Bae, Sung Kim, Yang Won Min, Hyuk Lee, Jun Haeng Lee, Poong-Lyul Rhee, Jae J. Kim, Su Jin Lee, Seung Tae Kim, Jeeyun Lee, Se Hoon Park, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Won Ki Kang, Hyun Joo An,  and Jung Hoe Kim
11094-11104
Abstract  |  PDF  |  HTML  |  Order a Reprint

Nuclear receptor retinoid-related orphan receptor alpha promotes apoptosis but is reduced in human gastric cancer

Nuclear receptor retinoid-related orphan receptor alpha promotes apoptosis but is reduced in human gastric cancer

https://doi.org/10.18632/oncotarget.14364

Zhengguang Wang, Fangyuan Xiong, Xiaoshan Wang, Yijun Qi, Haoyuan Yu, Yong Zhu,  and Huaqing Zhu
11105-11113
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Non-malignant respiratory epithelial cells preferentially proliferate from resected non-small cell lung cancer specimens cultured under conditionally reprogrammed conditions

Non-malignant respiratory epithelial cells preferentially proliferate from resected non-small cell lung cancer specimens cultured under conditionally reprogrammed conditions

https://doi.org/10.18632/oncotarget.14366

Boning Gao, Chunxian Huang, Kemp Kernstine, Vasiliki Pelekanou, Yuval Kluger, Tingting Jiang, Jennifer R. Peters-Hall, Melissa Coquelin, Luc Girard, Wei Zhang, Kenneth Huffman, Dwight Oliver, Fumi Kinose, Eric Haura, Jamie K. Teer, Uwe Rix, Anh T. Le, Dara L. Aisner, Marileila Varella- Garcia, Robert C. Doebele, Kyle R. Covington, Oliver A. Hampton, Harsha V. Doddapaneni, Joy C. Jayaseelan, Jianhong Hu, David A. Wheeler, Jerry W. Shay, David L. Rimm, Adi Gazdar,  and John D. Minna
11114-11126
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oxidative stress-induced epigenetic changes associated with malignant transformation of human kidney epithelial cells

Oxidative stress-induced epigenetic changes associated with malignant transformation of human kidney epithelial cells

https://doi.org/10.18632/oncotarget.12091

Prathap Kumar S. Mahalingaiah, Logeswari Ponnusamy,  and Kamaleshwar P. Singh
11127-11143
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CD133 in brain tumor: the prognostic factor

CD133 in brain tumor: the prognostic factor

https://doi.org/10.18632/oncotarget.14406

Bin Li, Cian M. McCrudden, Hiu Fung Yuen, Xinping Xi, Peng Lyu, Kwok Wah Chan, Shu Dong Zhang,  and Hang Fai Kwok
11144-11159
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Central spindle proteins and mitotic kinesins are direct transcriptional targets of MuvB, B-MYB and FOXM1 in breast cancer cell lines and are potential targets for therapy

Central spindle proteins and mitotic kinesins are direct transcriptional targets of MuvB, B-MYB and FOXM1 in breast cancer cell lines and are potential targets for therapy

https://doi.org/10.18632/oncotarget.14466

Patrick Wolter, Steffen Hanselmann, Grit Pattschull, Eva Schruf,  and Stefan Gaubatz
11160-11172
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Multidrug resistance transporter profile reveals MDR3 as a marker for stratification of blastemal Wilms tumour patients

Multidrug resistance transporter profile reveals MDR3 as a marker for stratification of blastemal Wilms tumour patients

https://doi.org/10.18632/oncotarget.14491

Lourdes Hontecillas-Prieto, Daniel J. Garcia-Dominguez, Diego Pascual Vaca, Rosa Garcia-Mejias, David Marcilla, Gema L. Ramirez-Villar, Carmen Saez,  and Enrique de Álava
11173-11186
Abstract  |  PDF  |  HTML  |  Order a Reprint

Keap1/Nrf2 pathway in kidney cancer: frequent methylation of KEAP1 gene promoter in clear renal cell carcinoma

Keap1/Nrf2 pathway in kidney cancer: frequent methylation of KEAP1 gene promoter in clear renal cell carcinoma

https://doi.org/10.18632/oncotarget.14492

Federico Pio Fabrizio, Manuela Costantini, Massimiliano Copetti, Annamaria la Torre, Angelo Sparaneo, Andrea Fontana, Luana Poeta, Michele Gallucci, Steno Sentinelli, Paolo Graziano, Paola Parente, Vincenzo Pompeo, Laura De Salvo, Giuseppe Simone, Rocco Papalia, Francesco Picardo, Teresa Balsamo, Gerardo Paolo Flammia, Domenico Trombetta, Angela Pantalone, Klaas Kok, Ferronika Paranita, Lucia Anna Muscarella,  and Vito Michele Fazio
11187-11198
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Easily detectable cytomorphological features to evaluate during ROSE for rapid lung cancer diagnosis: from cytology to histology

Easily detectable cytomorphological features to evaluate during ROSE for rapid lung cancer diagnosis: from cytology to histology

https://doi.org/10.18632/oncotarget.13204

Sara Ravaioli, Sara Bravaccini, Maria Maddalena Tumedei, Flavio Pironi, Piero Candoli,  and Maurizio Puccetti
11199-11205
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Combination of Arsenic trioxide and Everolimus (Rad001) synergistically induces both autophagy and apoptosis in prostate cancer cells

Combination of Arsenic trioxide and Everolimus (Rad001) synergistically induces both autophagy and apoptosis in prostate cancer cells

https://doi.org/10.18632/oncotarget.14493

Sheng Tai, Lingfan Xu, Ming Xu, Ligang Zhang, Yangyang Zhang, Kaipin Zhang, Li Zhang,  and Chaozhao Liang
11206-11218
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Synthetic high-density lipoproteins as targeted monotherapy for chronic lymphocytic leukemia

Synthetic high-density lipoproteins as targeted monotherapy for chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.14494

Kaylin M. McMahon, Cristina Scielzo, Nicholas L. Angeloni, Elad Deiss-Yehiely, Lydia Scarfo, Pamela Ranghetti, Shuo Ma, Jason Kaplan, Federica Barbaglio, Leo I. Gordon, Francis J. Giles, C. Shad Thaxton,  and Paolo Ghia
11219-11227
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IL-6/STAT3/TWIST inhibition reverses ionizing radiation-induced EMT and radioresistance in esophageal squamous carcinoma

IL-6/STAT3/TWIST inhibition reverses ionizing radiation-induced EMT and radioresistance in esophageal squamous carcinoma

https://doi.org/10.18632/oncotarget.14495

Chunbao Zang, Xujie Liu, Bing Li, Yanqiong He, Shen Jing, Yujia He, Wenli Wu, Bingqian Zhang, Shuhong Ma, Weiwei Dai, Shaolin Li,  and Zhiping Peng
11228-11238
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells

Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells

https://doi.org/10.18632/oncotarget.14496

Raymond Wong, Ekaterina Turlova, Zhong-Ping Feng, James T. Rutka,  and Hong-Shuo Sun
11239-11248
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Identifying genetic hypomethylation and upregulation of toll-like receptors in Kawasaki disease

Identifying genetic hypomethylation and upregulation of toll-like receptors in Kawasaki disease

https://doi.org/10.18632/oncotarget.14497

Ying-Hsien Huang, Sung-Chou Li, Lien-Hung Huang, Pao-Chun Chen, Yi-Yu Lin, Chiung-Chun Lin,  and Ho-Chang Kuo
11249-11258
Abstract  |  PDF  |  HTML  |  Order a Reprint

Endoscopic versus laparoscopic resection of gastric gastrointestinal stromal tumors: a multicenter study

Endoscopic versus laparoscopic resection of gastric gastrointestinal stromal tumors: a multicenter study

https://doi.org/10.18632/oncotarget.13298

Wei-Jie Dai, Gao Liu, Min Wang, Wen-Jie Liu, Wei Song, Xiao-Zhong Yang, Qi-Long Wang, Xiao-Yu Zhang,  and Zhi-Ning Fan
11259-11267
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MET receptor variant R970C favors calpain-dependent generation of a fragment promoting epithelial cell scattering

MET receptor variant R970C favors calpain-dependent generation of a fragment promoting epithelial cell scattering

https://doi.org/10.18632/oncotarget.14499

Rémi Montagne, Anne Baranzelli, Ghaffar Muharram, Leroy Catherine, Marie Lesaffre, Audrey Vinchent, Zoulika Kherrouche, Elisabeth Werkmeister, Alexis B. Cortot,  and David Tulasne
11268-11283
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SIRPα-antibody fusion proteins stimulate phagocytosis and promote elimination of acute myeloid leukemia cells

SIRPα-antibody fusion proteins stimulate phagocytosis and promote elimination of acute myeloid leukemia cells

https://doi.org/10.18632/oncotarget.14500

Laia Pascual Ponce, Nadja C. Fenn, Nadine Moritz, Christina Krupka, Jan-Hendrik Kozik, Kirsten Lauber, Marion Subklewe,  and Karl-Peter Hopfner
11284-11301
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Secretion modification region-derived peptide blocks exosome release and mediates cell cycle arrest in breast cancer cells

Secretion modification region-derived peptide blocks exosome release and mediates cell cycle arrest in breast cancer cells

https://doi.org/10.18632/oncotarget.14513

Ming-Bo Huang, Ruben R. Gonzalez, James Lillard,  and Vincent C. Bond
11302-11315
Abstract  |  PDF  |  HTML  |  Order a Reprint

Aeroallergen Der p 2 promotes motility of human non-small cell lung cancer cells via toll-like receptor-mediated up-regulation of urokinase-type plasminogen activator and integrin/focal adhesion kinase signaling

Aeroallergen Der p 2 promotes motility of human non-small cell lung cancer cells via toll-like receptor-mediated up-regulation of urokinase-type plasminogen activator and integrin/focal adhesion kinase signaling

https://doi.org/10.18632/oncotarget.14514

Chun-Hsiang Lin, Hui-Han Lin, Cheng-Yi Kuo,  and Shao-Hsuan Kao
11316-11328
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LSD1 binds to HPV16 E7 and promotes the epithelial-mesenchymal transition in cervical cancer by demethylating histones at the Vimentin promoter

LSD1 binds to HPV16 E7 and promotes the epithelial-mesenchymal transition in cervical cancer by demethylating histones at the Vimentin promoter

https://doi.org/10.18632/oncotarget.13516

Yuan Liu, Yanan Wang, Chunqin Chen, Jiawen Zhang, Wenyan Qian, Yu Dong, Zhiqiang Liu, Xi Zhang, Xiaoyun Wang, Zhenbo Zhang, Xiaobing Shi,  and Sufang Wu
11329-11342
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-874-3p is down-regulated in hepatocellular carcinoma and negatively regulates PIN1 expression

miR-874-3p is down-regulated in hepatocellular carcinoma and negatively regulates PIN1 expression

https://doi.org/10.18632/oncotarget.14526

Ka-Wai Leong, Chi-Wai Cheng, Chun-Ming Wong, Irene Oi-Lin Ng, Yok-Lam Kwong,  and Eric Tse
11343-11355
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MiR-410 induces stemness by inhibiting Gsk3β but upregulating β-catenin in non-small cells lung cancer

MiR-410 induces stemness by inhibiting Gsk3β but upregulating β-catenin in non-small cells lung cancer

https://doi.org/10.18632/oncotarget.14529

Xixian Ke, Yue Yuan, Chenglin Guo, Yan Yang, Qiang Pu, Xueting Hu, Kui Tang, Xinmei Luo, Qianqian Jiang, Xiaolan Su, Lunxu Liu, Wen Zhu,  and Yuquan Wei
11356-11371
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The correlation of age with chemotherapy-induced ovarian function failure in breast cancer patients

The correlation of age with chemotherapy-induced ovarian function failure in breast cancer patients

https://doi.org/10.18632/oncotarget.14532

Ingeborg J.H. Vriens, Ashley J.R. De Bie, Maureen J.B. Aarts, Maaike de Boer, Irene E.G. van Hellemond, Joyce H.E. Roijen, Ron J.T. van Golde, Adri C. Voogd,  and Vivianne C.G. Tjan-Heijnen
11372-11379
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Nomogram analysis and external validation to predict the risk of lymph node metastasis in gastric cancer

Nomogram analysis and external validation to predict the risk of lymph node metastasis in gastric cancer

https://doi.org/10.18632/oncotarget.14535

Shi Chen, Run-Cong Nie, Li-Ying OuYang, Yuan-Fang Li, Jun Xiang, Zhi-Wei Zhou, YingBo Chen,  and JunSheng Peng
11380-11388
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Fe3O4 nanoparticles and cryoablation enhance ice crystal formation to improve the efficiency of killing breast cancer cells

Fe3O4 nanoparticles and cryoablation enhance ice crystal formation to improve the efficiency of killing breast cancer cells

https://doi.org/10.18632/oncotarget.13859

Ping Ye, Yu Kong, Xiaojing Chen, Weijie Li, Dejun Liu, Yuexia Xie, Yan Zhou, Hanbing Zou, Zhaohua Chang, Huili Dai, Xianming Kong,  and Peifeng Liu
11389-11399
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MicroRNA-17 is downregulated in esophageal adenocarcinoma cancer stem-like cells and promotes a radioresistant phenotype

MicroRNA-17 is downregulated in esophageal adenocarcinoma cancer stem-like cells and promotes a radioresistant phenotype

https://doi.org/10.18632/oncotarget.13940

Niamh Lynam-Lennon, Susan Heavey, Gary Sommerville, Becky A.S. Bibby, Brendan Ffrench, Jennifer Quinn, Claudia Gasch, John J. O’Leary, Michael F. Gallagher, John V. Reynolds,  and Stephen G. Maher
11400-11413
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Tumor cell migration is inhibited by a novel therapeutic strategy antagonizing the alpha-7 receptor

Tumor cell migration is inhibited by a novel therapeutic strategy antagonizing the alpha-7 receptor

https://doi.org/10.18632/oncotarget.14545

Chris Pepper, Henry Tu, Paul Morrill, Sara Garcia-Rates, Chris Fegan,  and Susan Greenfield
11414-11424
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Chinese herb cinobufagin-reduced cancer pain is associated with increased peripheral opioids by invaded CD3/4/8 lymphocytes

Chinese herb cinobufagin-reduced cancer pain is associated with increased peripheral opioids by invaded CD3/4/8 lymphocytes

https://doi.org/10.18632/oncotarget.14005

Tao Chen, Shenjun Yuan, Xin-nian Wan, Ling Zhan, Xue-qin Yu, Jian-hong Zeng, Hong Li, Wen Zhang, Xiang-yang Hu, Yi-fei Ye,  and Wei Hu
11425-11441
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Repression of Fyn-related kinase in breast cancer cells is associated with promoter site-specific CpG methylation

Repression of Fyn-related kinase in breast cancer cells is associated with promoter site-specific CpG methylation

https://doi.org/10.18632/oncotarget.14546

Edward T. Bagu, Sayem Miah, Chenlu Dai, Travis Spriggs, Yetunde Ogunbolude, Erika Beaton, Michelle Sanders, Raghuveera K. Goel, Keith Bonham,  and Kiven E. Lukong
11442-11459
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Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing

Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing

https://doi.org/10.18632/oncotarget.14004

Florian Selt, Juliane Hohloch, Thomas Hielscher, Felix Sahm, David Capper, Andrey Korshunov, Diren Usta, Sebastian Brabetz, Johannes Ridinger, Jonas Ecker, Ina Oehme, Jan Gronych, Viktoria Marquardt, David Pauck, Heidi Bächli, Charles D. Stiles, Andreas von Deimling, Marc Remke, Martin U. Schuhmann, Stefan M. Pfister, Tilman Brummer, David T.W. Jones, Olaf Witt,  and Till Milde
11460-11479
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Radiotherapy improves survival in early stage extranodal natural killer/T cell lymphoma patients receiving asparaginase-based chemotherapy

Radiotherapy improves survival in early stage extranodal natural killer/T cell lymphoma patients receiving asparaginase-based chemotherapy

https://doi.org/10.18632/oncotarget.14006

Yi-Yang Li, Ling-Ling Feng, Shao-Qing Niu, Han-Yu Wang, Lu-Lu Zhang, Liang Wang, Zhong-Jun Xia, Hui-Qiang Huang, Yun-Fei Xia, Yu-Jing Zhang,  and Xi-Cheng Wang
11480-11488
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Overexpression of colorectal cancer oncogene CHRDL2 predicts a poor prognosis

Overexpression of colorectal cancer oncogene CHRDL2 predicts a poor prognosis

https://doi.org/10.18632/oncotarget.14039

Jian Sun, Xuan Liu, Hong Gao, Long Zhang, Qing Ji, Ziyuan Wang, Lihong Zhou2, Yan Wang, Hua Sui, Zhongze Fan,  and Qi Li
11489-11506
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of a synonymous variant in TRIM59 gene for gastric cancer risk in a Chinese population

Identification of a synonymous variant in TRIM59 gene for gastric cancer risk in a Chinese population

https://doi.org/10.18632/oncotarget.14075

Dakui Luo, Younan Wang, Xiangkun Huan, Chi Huang, Chao Yang, Hao Fan, Zekuan Xu,  and Li Yang
11507-11516
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Characterization of RNA editome in primary and metastatic lung adenocarcinomas

Characterization of RNA editome in primary and metastatic lung adenocarcinomas

https://doi.org/10.18632/oncotarget.14076

Lihua Peng, Leo J. Lee, Heng Xiong, Hong Su, Junhua Rao, Dakai Xiao, Jianxing He, Kui Wu,  and Dongbing Liu
11517-11529
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A novel ZEB1/HAS2 positive feedback loop promotes EMT in breast cancer

A novel ZEB1/HAS2 positive feedback loop promotes EMT in breast cancer

https://doi.org/10.18632/oncotarget.14563

Bogdan-Tiberius Preca, Karolina Bajdak, Kerstin Mock, Waltraut Lehmann, Vignesh Sundararajan, Peter Bronsert, Alexandra Matzge-Ogi, Véronique Orian-Rousseau, Simone Brabletz, Thomas Brabletz, Jochen Maurer,  and Marc P. Stemmler
11530-11543
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

B-cell lymphomas involving Waldeyer’s ring characterized by distinctive clinical and histopathological features: a comparison of pediatric to adult patients

B-cell lymphomas involving Waldeyer’s ring characterized by distinctive clinical and histopathological features: a comparison of pediatric to adult patients

https://doi.org/10.18632/oncotarget.14581

Lei Chen, Lika’a Fasih Y. Al-Kzayer, Yi Liu,  and Tingting Liu
11544-11554
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Dexamethasone induces docetaxel and cisplatin resistance partially through up-regulating Krüppel-like factor 5 in triple-negative breast cancer

Dexamethasone induces docetaxel and cisplatin resistance partially through up-regulating Krüppel-like factor 5 in triple-negative breast cancer

https://doi.org/10.18632/oncotarget.14135

Zhen Li, Jian Dong, Tianning Zou, Chengzhi Du, Siyuan Li, Ceshi Chen, Rong Liu,  and Kunhua Wang
11555-11565
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Anaplastic lymphoma kinase L1198F and G1201E mutations identified in anaplastic thyroid cancer patients are not ligand-independent

Anaplastic lymphoma kinase L1198F and G1201E mutations identified in anaplastic thyroid cancer patients are not ligand-independent

https://doi.org/10.18632/oncotarget.14141

Jikui Guan, Georg Wolfstetter, Joachim Siaw, Damini Chand, Fredrik Hugosson, Ruth H. Palmer,  and Bengt Hallberg
11566-11578
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Leukocytosis and neutrophilia predict outcome in locally advanced esophageal cancer treated with definitive chemoradiation

Leukocytosis and neutrophilia predict outcome in locally advanced esophageal cancer treated with definitive chemoradiation

https://doi.org/10.18632/oncotarget.14584

Antoine Schernberg, Laurence Moureau-Zabotto, Eleonor Rivin Del Campo, Alexandre Escande, Michel Ducreux, France Nguyen, Diane Goere, Cyrus Chargari,  and Eric Deutsch
11579-11588
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genomic expression differences between cutaneous cells from red hair color individuals and black hair color individuals based on bioinformatic analysis

Genomic expression differences between cutaneous cells from red hair color individuals and black hair color individuals based on bioinformatic analysis

https://doi.org/10.18632/oncotarget.14140

Joan Anton Puig-Butille, Pol Gimenez-Xavier, Alessia Visconti, Jérémie Nsengimana, Francisco Garcia-García, Gemma Tell-Marti, Maria José Escamez, Julia Newton-Bishop, Veronique Bataille, Marcela del Río, Joaquín Dopazo, Mario Falchi,  and Susana Puig
11589-11599
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells

Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells

https://doi.org/10.18632/oncotarget.14591

Renate Wagner, Gerald Stübiger, Daniel Veigel, Michael Wuczkowski, Peter Lanzerstorfer, Julian Weghuber, Emmanouil Karteris, Karin Nowikovsky, Nastasia Wilfinger-Lutz, Christian F. Singer, Ramón Colomer, Bellinda Benhamú, María Luz López-Rodríguez, Peter Valent,  and Thomas W. Grunt
11600-11613
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Asthma and the risk of lung cancer: a meta-analysis

Asthma and the risk of lung cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.14595

Yan-Liang Qu, Jun Liu, Li-Xin Zhang, Chun-Min Wu, Ai-Jie Chu, Bao-Lei Wen, Chao Ma, Xu-yan Yan, Xin Zhang, De-Ming Wang, Xin Lv,  and Shu-Jian Hou
11614-11620
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Matrine alleviates lipopolysaccharide-induced intestinal inflammation and oxidative stress via CCR7 signal

Matrine alleviates lipopolysaccharide-induced intestinal inflammation and oxidative stress via CCR7 signal

https://doi.org/10.18632/oncotarget.14598

Wenhong Zhou, Junfeng Zhao, Xiaohua Pan, Yongjie Sun, Hao Xu, Peng Shi, Chong Geng, Ling Gao,  and Xingsong Tian
11621-11628
Abstract  |  PDF  |  HTML  |  Order a Reprint

The SDF-1/CXCR4 axis promotes recovery after spinal cord injury by mediating bone marrow-derived from mesenchymal stem cells

The SDF-1/CXCR4 axis promotes recovery after spinal cord injury by mediating bone marrow-derived from mesenchymal stem cells

https://doi.org/10.18632/oncotarget.14619

Guo-Dong Wang, Yi-Xun Liu, Xiao Wang, Yong-Le Zhang, Ya-Dong Zhang,  and Feng Xue
11629-11640
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase

MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase

https://doi.org/10.18632/oncotarget.14264

Recep Bayraktar, Martin Pichler, Pinar Kanlikilicer, Cristina Ivan, Emine Bayraktar, Nermin Kahraman, Burcu Aslan, Serpil Oguztuzun, Mustafa Ulasli, Ahmet Arslan, George Calin, Gabriel Lopez-Berestein,  and Bulent Ozpolat
11641-11658
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ZGDHu-1 promotes apoptosis of mantle cell lymphoma cells

ZGDHu-1 promotes apoptosis of mantle cell lymphoma cells

https://doi.org/10.18632/oncotarget.14274

Liannv Qiu, Zhenni Wang, Sufeng Chen, Weixiao Hu, Qiang Huang,  and Yonglie Zhou
11659-11675
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)- 1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines

A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)- 1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines

https://doi.org/10.18632/oncotarget.14644

Elke Nolte, Sven Wach, Izabella Thais Silva, Sabine Lukat, Arif B. Ekici, Jennifer Munkert, Frieder Müller-Uri, Wolfgang Kreis, Cláudia Maria Oliveira Simões, Julio Vera, Bernd Wullich, Helge Taubert,  and Xin Lai
11676-11691
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activating transcription factor 3 is crucial for antitumor activity and to strengthen the antiviral properties of Onconase

Activating transcription factor 3 is crucial for antitumor activity and to strengthen the antiviral properties of Onconase

https://doi.org/10.18632/oncotarget.14302

Anna Vert, Jessica Castro, Marc Ribó, Antoni Benito,  and Maria Vilanova
11692-11707
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TLR-activated plasmacytoid dendritic cells inhibit breast cancer cell growth in vitro and in vivo

TLR-activated plasmacytoid dendritic cells inhibit breast cancer cell growth in vitro and in vivo

https://doi.org/10.18632/oncotarget.14315

Jing Wu, Shuang Li, Yang Yang, Shan Zhu, Mingyou Zhang, Yuan Qiao, Yong-Jun Liu,  and Jingtao Chen
11708-11718
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Yes-associated protein 1 promotes papillary thyroid cancer cell proliferation by activating the ERK/MAPK signaling pathway

Yes-associated protein 1 promotes papillary thyroid cancer cell proliferation by activating the ERK/MAPK signaling pathway

https://doi.org/10.18632/oncotarget.14319

Tian Liao, Duo Wen, Ben Ma, Jia-Qian Hu, Ning Qu, Rong-Liang Shi, Liang Liu, Qing Guan, Duan-Shu Li,  and Qing-Hai Ji
11719-11728
Abstract  |  PDF  |  HTML  |  Order a Reprint

Matrine derivative YF-18 inhibits lung cancer cell proliferation and migration through down-regulating Skp2

Matrine derivative YF-18 inhibits lung cancer cell proliferation and migration through down-regulating Skp2

https://doi.org/10.18632/oncotarget.14329

Lichuan Wu, Guizhen Wang, Jinrui Wei, Na Huang, Sen Zhang, Fangfang Yang, Ming Li, Guangbiao Zhou,  and Lisheng Wang
11729-11738
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Evolutionary selected Tibetan variants of HIF pathway and risk of lung cancer

Evolutionary selected Tibetan variants of HIF pathway and risk of lung cancer

https://doi.org/10.18632/oncotarget.14340

Lucie Lanikova, N. Scott Reading, Hao Hu, Tsewang Tashi, Tatiana Burjanivova, Anna Shestakova, Bhola Siwakoti, Binay Kumar Thakur, Chin Bahadur Pun, Amir Sapkota, Sarah Abdelaziz, Bing-Jian Feng, Chad D. Huff, Mia Hashibe,  and Josef T. Prchal
11739-11747
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Establishment and characterization of hypomethylating agent-resistant cell lines, MOLM/AZA-1 and MOLM/DEC-5

Establishment and characterization of hypomethylating agent-resistant cell lines, MOLM/AZA-1 and MOLM/DEC-5

https://doi.org/10.18632/oncotarget.14342

Eun-Hye Hur, Seung-Hyun Jung, Bon-Kwan Goo, Juhyun Moon, Yunsuk Choi, Dae Ro Choi, Yeun-Jun Chung,  and Je-Hwan Lee
11748-11762
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Arg-Leu-Tyr-Glu tetrapeptide inhibits tumor progression by suppressing angiogenesis and vascular permeability via VEGF receptor-2 antagonism

Arg-Leu-Tyr-Glu tetrapeptide inhibits tumor progression by suppressing angiogenesis and vascular permeability via VEGF receptor-2 antagonism

https://doi.org/10.18632/oncotarget.14343

Yi-Yong Baek, Dong-Keon Lee, Joohwan Kim, Ji-Hee Kim, Wonjin Park, Taesam Kim, Sanghwa Han, Dooil Jeoung, Ji Chang You, Hansoo Lee, Moo-Ho Won, Kwon-Soo Ha, Young-Guen Kwon,  and Young-Myeong Kim
11763-11777
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The prognostic significance of postoperative neutrophil-to-lymphocyte ratio after radical prostatectomy for localized prostate cancer

The prognostic significance of postoperative neutrophil-to-lymphocyte ratio after radical prostatectomy for localized prostate cancer

https://doi.org/10.18632/oncotarget.14349

Won Sik Jang, Kang Su Cho, Myung Soo Kim, Cheol Yong Yoon, Dong Hyuk Kang, Yong Jin Kang, Won Sik Jeong, Won Sik Ham,  and Young Deuk Choi
11778-11787
Abstract  |  PDF  |  HTML  |  Order a Reprint

GLUT-1 overexpression as an unfavorable prognostic biomarker in patients with colorectal cancer

GLUT-1 overexpression as an unfavorable prognostic biomarker in patients with colorectal cancer

https://doi.org/10.18632/oncotarget.14352

Jing Yang, Jing Wen, Tian Tian, Zhongsheng Lu, Yao Wang, Zikai Wang, Xiangdong Wang,  and Yunsheng Yang
11788-11796
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Subconjunctival injection of antagomir-21 alleviates corneal neovascularization in a mouse model of alkali-burned cornea

Subconjunctival injection of antagomir-21 alleviates corneal neovascularization in a mouse model of alkali-burned cornea

https://doi.org/10.18632/oncotarget.14370

Yun Zhang, Ting Zhang, Xiaoyun Ma,  and Jun Zou
11797-11808
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of microRNAs implicated in the late differentiation stages of normal B cells suggests a central role for miRNA targets ZEB1 and TP53

Identification of microRNAs implicated in the late differentiation stages of normal B cells suggests a central role for miRNA targets ZEB1 and TP53

https://doi.org/10.18632/oncotarget.14683

Giorgio Malpeli, Stefano Barbi, Simonetta Zupo, Gabriele Tosadori, Giovanni Scardoni, Anna Bertolaso, Silvia Sartoris, Stefano Ugel, Caterina Vicentini, Matteo Fassan, Annalisa Adamo, Mauro Krampera, Maria Teresa Scupoli, Carlo Maria Croce,  and Aldo Scarpa
11809-11826
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TMPRSS2-ERG fusion promotes prostate cancer metastases in bone

TMPRSS2-ERG fusion promotes prostate cancer metastases in bone

https://doi.org/10.18632/oncotarget.14399

Rachel Deplus, Carine Delliaux, Nathalie Marchand, Anne Flourens, Nathalie Vanpouille, Xavier Leroy, Yvan de Launoit,  and Martine Duterque-Coquillaud
11827-11840
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mitochondrial deficiency impairs hypoxic induction of HIF-1 transcriptional activity and retards tumor growth

Mitochondrial deficiency impairs hypoxic induction of HIF-1 transcriptional activity and retards tumor growth

https://doi.org/10.18632/oncotarget.14415

Masaru Koido, Naomi Haga, Aki Furuno, Satomi Tsukahara, Junko Sakurai, Yuri Tani, Shigeo Sato,  and Akihiro Tomida
11841-11854
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

25-Hydroxycholesterol is involved in the pathogenesis of amyotrophic lateral sclerosis

25-Hydroxycholesterol is involved in the pathogenesis of amyotrophic lateral sclerosis

https://doi.org/10.18632/oncotarget.14416

Sung-Min Kim, Min-Young Noh, Heejaung Kim, So-Young Cheon, Kang Mi Lee, Jaeick Lee, Eunju Cha, Kyung Seok Park, Kwang-Woo Lee, Jung-Joon Sung,  and Seung Hyun Kim
11855-11867
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Large-scale DNA methylation expression analysis across 12 solid cancers reveals hypermethylation in the calcium-signaling pathway

Large-scale DNA methylation expression analysis across 12 solid cancers reveals hypermethylation in the calcium-signaling pathway

https://doi.org/10.18632/oncotarget.14417

Xiao-Xiong Wang, Fu-Hui Xiao, Qi-Gang Li, Jia Liu, Qing-Peng Kong,  and Yong-Han He
11868-11876
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clostridium difficile colonization in preoperative colorectal cancer patients

Clostridium difficile colonization in preoperative colorectal cancer patients

https://doi.org/10.18632/oncotarget.14424

Yi Zheng, Yun Luo, Yinxiang Lv, Chen Huang, Qinsong Sheng, Peng Zhao, Julian Ye, Weiqin Jiang, Lulu Liu, Xiaojun Song, Zhou Tong, Wenbin Chen, Jianjiang Lin, Yi-Wei Tang, Dazhi Jin,  and Weijia Fang
11877-11886
Abstract  |  PDF  |  HTML  |  Order a Reprint

Antitumor and antimetastatic activities of a novel benzothiazole-2-thiol derivative in a murine model of breast cancer

Antitumor and antimetastatic activities of a novel benzothiazole-2-thiol derivative in a murine model of breast cancer

https://doi.org/10.18632/oncotarget.14431

XiaoLin Hu, Sen Li, Yan He, Ping Ai, Shaoyong Wu, Yonglin Su, Xiaolin Li, Lei Cai,  and Xingchen Peng
11887-11895
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High expression of miR-105-1 positively correlates with clinical prognosis of hepatocellular carcinoma by targeting oncogene NCOA1

High expression of miR-105-1 positively correlates with clinical prognosis of hepatocellular carcinoma by targeting oncogene NCOA1

https://doi.org/10.18632/oncotarget.14435

Yu-Shui Ma, Ting-Miao Wu, Zhong-Wei Lv, Gai-Xia Lu, Xian-Ling Cong, Ru-Ting Xie, Hui-Qiong Yang, Zheng-Yan Chang, Ran Sun, Li Chai, Ming-Xiang Cai, Xiao-Jun Zhong, Jian Zhu,  and Da Fu
11896-11905
Abstract  |  PDF  |  HTML  |  Order a Reprint

LINE-1 hypomethylation status of circulating cell-free DNA in plasma as a biomarker for colorectal cancer

LINE-1 hypomethylation status of circulating cell-free DNA in plasma as a biomarker for colorectal cancer

https://doi.org/10.18632/oncotarget.14439

Yuzo Nagai, Eiji Sunami, Yoko Yamamoto, Keisuke Hata, Satoshi Okada, Koji Murono, Koji Yasuda, Kensuke Otani, Takeshi Nishikawa, Toshiaki Tanaka, Tomomichi Kiyomatsu, Kazushige Kawai, Hiroaki Nozawa, Soichiro Ishihara, Dave S.B. Hoon,  and Toshiaki Watanabe
11906-11916
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Exosomes as mediators of platinum resistance in ovarian cancer

Exosomes as mediators of platinum resistance in ovarian cancer

https://doi.org/10.18632/oncotarget.14440

Jennifer Crow, Safinur Atay, Samagya Banskota, Brittany Artale, Sarah Schmitt,  and Andrew K. Godwin
11917-11936
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PI3K/mTOR dual inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A synergistically exert anti-tumor activity in breast cancer

PI3K/mTOR dual inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A synergistically exert anti-tumor activity in breast cancer

https://doi.org/10.18632/oncotarget.14442

Liyan Chen, Tiefeng Jin, Kun Zhu, Yingshi Piao, Taihao Quan, Chunji Quan,  and Zhenhua Lin
11937-11949
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Eukaryotic elongation factor 2 is a prognostic marker and its kinase a potential therapeutic target in HCC

Eukaryotic elongation factor 2 is a prognostic marker and its kinase a potential therapeutic target in HCC

https://doi.org/10.18632/oncotarget.14447

Leona L. Pott, Sascha Hagemann, Henning Reis, Kristina Lorenz, Thilo Bracht, Thomas Herold, Boris V. Skryabin, Dominik A. Megger, Julia Kälsch, Frank Weber, Barbara Sitek,  and Hideo A. Baba
11950-11962
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comparison of the tumor cell secretome and patient sera for an accurate serum-based diagnosis of pancreatic ductal adenocarcinoma

Comparison of the tumor cell secretome and patient sera for an accurate serum-based diagnosis of pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.14449

Shakhawan Mustafa, Longqiang Pan, Aseel Marzoq, Malak Fawaz, Laureen Sander, Felix Rückert, Andrea Schrenk, Christina Hartl, Rico Uhler, Adem Yildirim, Oliver Strobel, Thilo Hackert, Nathalia Giese, Markus W. Büchler, Jörg D. Hoheisel,  and Mohamed Saiel Saeed Alhamdani
11963-11976
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LOXL4 knockdown enhances tumor growth and lung metastasis through collagen-dependent extracellular matrix changes in triple-negative breast cancer

LOXL4 knockdown enhances tumor growth and lung metastasis through collagen-dependent extracellular matrix changes in triple-negative breast cancer

https://doi.org/10.18632/oncotarget.14450

Sul Ki Choi, Hoe Suk Kim, Tiefeng Jin,  and Woo Kyung Moon
11977-11989
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Autocrine VEGF signaling promotes cell proliferation through a PLC-dependent pathway and modulates Apatinib treatment efficacy in gastric cancer

Autocrine VEGF signaling promotes cell proliferation through a PLC-dependent pathway and modulates Apatinib treatment efficacy in gastric cancer

https://doi.org/10.18632/oncotarget.14467

Yi Lin, Ertao Zhai, Bing Liao, Lixia Xu, Xinhua Zhang, Sui Peng, Yulong He, Shirong Cai, Zhirong Zeng,  and Minhu Chen
11990-12002
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The regulator of calcineurin 1 (RCAN1) inhibits nuclear factor kappaB signaling pathway and suppresses human malignant glioma cells growth

The regulator of calcineurin 1 (RCAN1) inhibits nuclear factor kappaB signaling pathway and suppresses human malignant glioma cells growth

https://doi.org/10.18632/oncotarget.14479

Xin Chen, Yuanyuan Hu, Shuo Wang,  and Xiulian Sun
12003-12012
Abstract  |  PDF  |  HTML  |  Order a Reprint

Enhancement of the bioavailability of a novel anticancer compound (acetyltanshinone IIA) by encapsulation within mPEG-PLGA nanoparticles: a study of formulation optimization, toxicity, and pharmacokinetics

Enhancement of the bioavailability of a novel anticancer compound (acetyltanshinone IIA) by encapsulation within mPEG-PLGA nanoparticles: a study of formulation optimization, toxicity, and pharmacokinetics

https://doi.org/10.18632/oncotarget.14481

Qi Wang, Na Wei, Xiaofeng Liu,  and Kathy Qian Luo
12013-12030
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clonal evolution in therapy-related neoplasms

Clonal evolution in therapy-related neoplasms

https://doi.org/10.18632/oncotarget.14509

Emiliano Fabiani, Giulia Falconi, Luana Fianchi, Marianna Criscuolo, Tiziana Ottone, Laura Cicconi, Stefan Hohaus, Simona Sica, Massimiliano Postorino, Antonino Neri, Marta Lionetti, Giuseppe Leone, Francesco Lo-Coco,  and Maria Teresa Voso
12031-12040
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Systemically identifying and prioritizing risk lncRNAs through integration of pan-cancer phenotype associations

Systemically identifying and prioritizing risk lncRNAs through integration of pan-cancer phenotype associations

https://doi.org/10.18632/oncotarget.14510

Chaohan Xu, Rui Qi, Yanyan Ping, Jie Li, Hongying Zhao, Li Wang, Michael Yifei Du, Yun Xiao,  and Xia Li
12041-12051
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pax-5 is a potent regulator of E-cadherin and breast cancer malignant processes

Pax-5 is a potent regulator of E-cadherin and breast cancer malignant processes

https://doi.org/10.18632/oncotarget.14511

Sami Benzina, Annie-Pier Beauregard, Roxann Guerrette, Stéphanie Jean, Mame Daro Faye, Mark Laflamme, Emmanuel Maïcas, Nicolas Crapoulet, Rodney J. Ouellette,  and Gilles A. Robichaud
12052-12066
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sulforaphane inhibits cancer stem-like cell properties and cisplatin resistance through miR-214-mediated downregulation of c-MYC in non-small cell lung cancer

Sulforaphane inhibits cancer stem-like cell properties and cisplatin resistance through miR-214-mediated downregulation of c-MYC in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.14512

Qian-Qian Li, You-Ke Xie, Yue Wu, Lin-Lin Li, Ying Liu, Xiao-Bo Miao, Qiu-Zhen Liu, Kai-Tai Yao,  and Guang-Hui Xiao
12067-12080
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Effect of Trp53 gene deficiency on brain injury after neonatal hypoxia-ischemia

Effect of Trp53 gene deficiency on brain injury after neonatal hypoxia-ischemia

https://doi.org/10.18632/oncotarget.14518

Ana A. Baburamani, Kristina S. Sobotka, Regina Vontell, Carina Mallard, Veena G. Supramaniam, Claire Thornton,  and Henrik Hagberg
12081-12092
Abstract  |  PDF  |  HTML  |  Order a Reprint

Molecular dynamics simulation reveals how phosphorylation of tyrosine 26 of phosphoglycerate mutase 1 upregulates glycolysis and promotes tumor growth

Molecular dynamics simulation reveals how phosphorylation of tyrosine 26 of phosphoglycerate mutase 1 upregulates glycolysis and promotes tumor growth

https://doi.org/10.18632/oncotarget.14517

Yan Wang, Wen-Sheng Cai, Luonan Chen,  and Guanyu Wang
12093-12107
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Endovascular brachytherapy combined with portal vein stenting and transarterial chemoembolization improves overall survival of hepatocellular carcinoma patients with main portal vein tumor thrombus

Endovascular brachytherapy combined with portal vein stenting and transarterial chemoembolization improves overall survival of hepatocellular carcinoma patients with main portal vein tumor thrombus

https://doi.org/10.18632/oncotarget.14520

Tian-Zhu Yu, Wen Zhang, Qing-Xin Liu, Wen-Hui Li, Jing-Qin Ma, Zi-Han Zhang, Min-Jie Yang, Jian-Hua Wang, Bing Chen, Shao-Chong Zeng, Jian-Jun Luo, Ling-Xiao Liu,  and Zhi-Ping Yan
12108-12119
Abstract  |  PDF  |  HTML  |  Order a Reprint

Lysosomal acid phosphatase 2 is an unfavorable prognostic factor but is associated with better survival in stage II colorectal cancer patients receiving chemotherapy

Lysosomal acid phosphatase 2 is an unfavorable prognostic factor but is associated with better survival in stage II colorectal cancer patients receiving chemotherapy

https://doi.org/10.18632/oncotarget.14552

Yu-Chieh Lee, Chia-Yu Su, Yuan-Feng Lin, Chun-Mao Lin, Chih-Yeu Fang, Yen-Kuang Lin, Michael Hsiao,  and Chi-Long Chen
12120-12132
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

DUSP1 inhibits cell proliferation, metastasis and invasion and angiogenesis in gallbladder cancer

DUSP1 inhibits cell proliferation, metastasis and invasion and angiogenesis in gallbladder cancer

https://doi.org/10.18632/oncotarget.14815

Jiliang Shen, Senjun Zhou, Liang Shi, Xiaolong Liu, Hui Lin, Hong Yu, Xiao liang, Jiacheng Tang, Tunan Yu,  and Xiujun Cai
12133-12144
Abstract  |  PDF  |  HTML  |  Order a Reprint

Surgical debulking promotes recruitment of macrophages and triggers glioblastoma phagocytosis in combination with CD47 blocking immunotherapy

Surgical debulking promotes recruitment of macrophages and triggers glioblastoma phagocytosis in combination with CD47 blocking immunotherapy

https://doi.org/10.18632/oncotarget.14553

Huaiyang Zhu, Lina Leiss, Ning Yang, Cecilie B. Rygh, Siddhartha S. Mitra, Samuel H. Cheshier, Irving L. Weissman, Bin Huang, Hrvoje Miletic, Rolf Bjerkvig, Per Ø. Enger, Xingang Li,  and Jian Wang
12145-12157
Abstract  |  PDF  |  HTML  |  Order a Reprint

Human papillomavirus type 16 E6 suppresses microRNA-23b expression in human cervical cancer cells through DNA methylation of the host gene C9orf3

Human papillomavirus type 16 E6 suppresses microRNA-23b expression in human cervical cancer cells through DNA methylation of the host gene C9orf3

https://doi.org/10.18632/oncotarget.14555

Chi Lam Au Yeung, Tsun Yee Tsang, Pak Lun Yau,  and Tim Tak Kwok
12158-12173
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

NMI promotes hepatocellular carcinoma progression via BDKRB2 and MAPK/ERK pathway

NMI promotes hepatocellular carcinoma progression via BDKRB2 and MAPK/ERK pathway

https://doi.org/10.18632/oncotarget.14556

Jing Zhao, Qiong-Zhu Dong, Fan Zhong, Li-Li Cai, Zhao-Yu Qin, Yang Liu, Cheng-Zhao Lin, Lun-Xiu Qin,  and Fu-Chu He
12174-12185
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevated fibrous sheath interacting protein 1 levels are associated with poor prognosis in non-small cell lung cancer patients

Elevated fibrous sheath interacting protein 1 levels are associated with poor prognosis in non-small cell lung cancer patients

https://doi.org/10.18632/oncotarget.14575

Yuqiang Mao, Ran Xu, Xiaoying Liu, Wenjun Shi,  and Yun Han
12186-12193
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling

ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling

https://doi.org/10.18632/oncotarget.14577

Julhash U. Kazi, Kaja Rupar, Alissa Marhäll, Sausan A. Moharram, Fatima Khanum, Kinjal Shah, Mohiuddin Gazi, Sachin Raj M. Nagaraj, Jianmin Sun, Rohit A. Chougule,  and Lars Rönnstrand
12194-12202
Abstract  |  PDF  |  HTML  |  Order a Reprint

A nomogram to predict lymph node metastasis in patients with early gastric cancer

A nomogram to predict lymph node metastasis in patients with early gastric cancer

https://doi.org/10.18632/oncotarget.14660

Chun Guang Guo, Dong Bing Zhao, Qian Liu, Zhi Xiang Zhou, Ping Zhao, Gui Qi Wang,  and Jian Qiang Cai
12203-12210
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cordycepin induces apoptosis by caveolin-1-mediated JNK regulation of Foxo3a in human lung adenocarcinoma

Cordycepin induces apoptosis by caveolin-1-mediated JNK regulation of Foxo3a in human lung adenocarcinoma

https://doi.org/10.18632/oncotarget.14661

Jong Cheon Joo, Jung-Hoo Hwang, Eunbi Jo, Young-Rang Kim, Dae Joon Kim, Kyung-Bok Lee, Soo Jung Park,  and Ik-Soon Jang
12211-12224
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Low rate of positive margins and re-excision after partial mastectomy in highly selected breast cancer patients: A Chinese single-institution experience

Low rate of positive margins and re-excision after partial mastectomy in highly selected breast cancer patients: A Chinese single-institution experience

https://doi.org/10.18632/oncotarget.14686

Siyu Wu, Yanyan Zhu, Zhaozhi Yang, Miao Mo, Hongbo Gao, Wentao Yang,  and Guangyu Liu
12225-12233
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells

Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells

https://doi.org/10.18632/oncotarget.14685

Alison Roos, Harshil D. Dhruv, Ian T. Mathews, Landon J. Inge, Serdar Tuncali, Lauren K. Hartman, Donald Chow, Nghia Millard, Holly H. Yin, Jean Kloss, Joseph C. Loftus, Jeffrey A. Winkles, Michael E. Berens,  and Nhan L. Tran
12234-12246
Abstract  |  PDF  |  HTML  |  Order a Reprint

68Ga-PSMA-11 PET/CT for prostate cancer staging and risk stratification in Chinese patients

68Ga-PSMA-11 PET/CT for prostate cancer staging and risk stratification in Chinese patients

https://doi.org/10.18632/oncotarget.14691

Shiming Zang, Guoqiang Shao, Can Cui, Tian-Nv Li, Yue Huang, Xiaochen Yao, Qiu Fan, Zejun Chen, Jin Du, Ruipeng Jia, Hongbin Sun, Zichun Hua, Jun Tang,  and Feng Wang
12247-12258
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Piwil2-transfected human fibroblasts are cancer stem cell-like and genetically unstable

Piwil2-transfected human fibroblasts are cancer stem cell-like and genetically unstable

https://doi.org/10.18632/oncotarget.14696

Deying Zhang, Xin Wu, Xing Liu, Chunhong Cai, Guangping Zeng, Jan Rohozinski, Yuanyuan Zhang, Guanghui Wei,  and Dawei He
12259-12271
Abstract  |  PDF  |  HTML  |  Order a Reprint

A new model of multi-visceral and bone metastatic prostate cancer with perivascular niche targeting by a novel endothelial specific adenoviral vector

A new model of multi-visceral and bone metastatic prostate cancer with perivascular niche targeting by a novel endothelial specific adenoviral vector

https://doi.org/10.18632/oncotarget.14699

Zhi Hong Lu, Sergey Kaliberov, Rebecca E. Sohn, Lyudmila Kaliberova, Yingqiu Du, Julie L. Prior, Daniel J. Leib, Anne Chauchereau, Jennifer K. Sehn, David T. Curiel,  and Jeffrey M. Arbeit
12272-12289
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association of RAB5 overexpression in pancreatic cancer with cancer progression and poor prognosis via E-cadherin suppression

Association of RAB5 overexpression in pancreatic cancer with cancer progression and poor prognosis via E-cadherin suppression

https://doi.org/10.18632/oncotarget.14703

Takamichi Igarashi, Kenichiro Araki, Takehiko Yokobori, Bolag Altan, Takahiro Yamanaka, Norihiro Ishii, Mariko Tsukagoshi, Akira Watanabe, Norio Kubo, Tadashi Handa, Yasuo Hosouchi, Masahiko Nishiyama, Tetsunari Oyama, Ken Shirabe,  and Hiroyuki Kuwano
12290-12300
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ellagic acid inhibits the proliferation of human pancreatic carcinoma PANC-1 cells in vitro and in vivo

Ellagic acid inhibits the proliferation of human pancreatic carcinoma PANC-1 cells in vitro and in vivo

https://doi.org/10.18632/oncotarget.14811

Hao Cheng, Chenglin Lu, Ribo Tang, Yiming Pan, Shanhua Bao, Yudong Qiu,  and Min Xie
12301-12310
Abstract  |  PDF  |  HTML  |  Order a Reprint

RXRα ligand Z-10 induces PML-RARα cleavage and APL cell apoptosis through disrupting PML-RARα/RXRα complex in a cAMP-independent manner

RXRα ligand Z-10 induces PML-RARα cleavage and APL cell apoptosis through disrupting PML-RARα/RXRα complex in a cAMP-independent manner

https://doi.org/10.18632/oncotarget.14812

Lin Xu, Zhiping Zeng, Weidong Zhang, Gaoang Ren, Xiaobin Ling, Fengyu Huang, Peizhen Xie, Ying Su, Xiao-kun Zhang,  and Hu Zhou
12311-12322
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Hypomethylation of HLA-DRB1 and its clinical significance in psoriasis

Hypomethylation of HLA-DRB1 and its clinical significance in psoriasis

https://doi.org/10.18632/oncotarget.12468

Wenkai Zong, Yiping Ge, Yue Han, Xueyuan Yang, Qi Li,  and Min Chen
12323-12332
Abstract  |  PDF  |  HTML  |  Order a Reprint

Novel circulating lipid measurements for current dyslipidemias in non-treated patients undergoing coronary angiography: PCSK9, apoC3 and sdLDL-C

Novel circulating lipid measurements for current dyslipidemias in non-treated patients undergoing coronary angiography: PCSK9, apoC3 and sdLDL-C

https://doi.org/10.18632/oncotarget.12471

Sha Li, Xi Zhao, Yan Zhang, Cheng-Gang Zhu, Yuan-Lin Guo, Na-Qiong Wu, Rui-Xia Xu, Ping Qing, Ying Gao, Jing Sun, Geng Liu, Qian Dong,  and Jian-Jun Li
12333-12341
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Better transplant outcome with pre-transplant marrow response after hypomethylating treatment in higher-risk MDS with excess blasts

Better transplant outcome with pre-transplant marrow response after hypomethylating treatment in higher-risk MDS with excess blasts

https://doi.org/10.18632/oncotarget.12511

Seung-Ah Yahng, Myungshin Kim, Tae-Min Kim, Young-Woo Jeon, Jae-Ho Yoon, Seung-Hwan Shin, Sung-Eun Lee, Ki-Seong Eom, Seok Lee, Chang-Ki Min, Hee-Je Kim, Dong-Wook Kim, Jong-Wook Lee, Woo-Sung Min,  and Yoo-Jin Kim
12342-12354
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preoperative peripheral plasma fibrinogen level is an independent prognostic marker in penile cancer

Preoperative peripheral plasma fibrinogen level is an independent prognostic marker in penile cancer

https://doi.org/10.18632/oncotarget.12563

Chengquan Ma, Yaguang zhou, Sufen Zhou, Kun Zhao, Bingxin Lu,  and Erlin Sun
12355-12363
Abstract  |  PDF  |  HTML  |  Order a Reprint

Aging, obesity, and post-therapy cognitive recovery in breast cancer survivors

Aging, obesity, and post-therapy cognitive recovery in breast cancer survivors

https://doi.org/10.18632/oncotarget.12565

Zhezhou Huang, Ying Zheng, Pingping Bao, Hui Cai, Zhen Hong, Ding Ding, James Jackson, Xiao-Ou Shu,  and Qi Dai
12364-12373
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

Autophagy, autophagy-associated adaptive immune responses and its role in hematologic malignancies

Autophagy, autophagy-associated adaptive immune responses and its role in hematologic malignancies

https://doi.org/10.18632/oncotarget.13583

Liangshun You, Shenhe Jin, Li Zhu,  and Wenbin Qian
12374-12388
Abstract  |  PDF  |  HTML  |  Order a Reprint

Bevacizumab in ovarian cancer: A critical review of phase III studies

Bevacizumab in ovarian cancer: A critical review of phase III studies

https://doi.org/10.18632/oncotarget.13310

Luigi Rossi, Monica Verrico, Eleonora Zaccarelli, Anselmo Papa, Maria Colonna, Martina Strudel, Patrizia Vici, Vincenzo Bianco,  and Federica Tomao
12389-12405
Abstract  |  PDF  |  HTML  |  Order a Reprint

What influences preneoplastic colorectal lesion recurrence?

What influences preneoplastic colorectal lesion recurrence?

https://doi.org/10.18632/oncotarget.13628

Giulia De Maio, Elisa Zama, Claudia Rengucci,  and Daniele Calistri
12406-12416
Abstract  |  PDF  |  HTML  |  Order a Reprint

Developmental therapeutics for inflammatory breast cancer: Biology and translational directions

Developmental therapeutics for inflammatory breast cancer: Biology and translational directions

https://doi.org/10.18632/oncotarget.13778

Ricardo Costa, Cesar A. Santa-Maria, Giovanna Rossi, Benedito A. Carneiro, Young Kwang Chae, William J. Gradishar, Francis J. Giles,  and Massimo Cristofanilli
12417-12432
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNAs as regulators and mediators of forkhead box transcription factors function in human cancers

MicroRNAs as regulators and mediators of forkhead box transcription factors function in human cancers

https://doi.org/10.18632/oncotarget.14015

Chen Li, Kai Zhang, Jing Chen, Longbang Chen, Rui Wang,  and Xiaoyuan Chu
12433-12450
Abstract  |  PDF  |  HTML  |  Order a Reprint

The role of prostate tumor overexpressed 1 in cancer progression

The role of prostate tumor overexpressed 1 in cancer progression

https://doi.org/10.18632/oncotarget.14104

Verónica Cánovas, Matilde Lleonart, Juan Morote,  and Rosanna Paciucci
12451-12471
Abstract  |  PDF  |  HTML  |  Order a Reprint

The crosstalk between lncRNA and microRNA in cancer metastasis: orchestrating the epithelial-mesenchymal plasticity

The crosstalk between lncRNA and microRNA in cancer metastasis: orchestrating the epithelial-mesenchymal plasticity

https://doi.org/10.18632/oncotarget.13957

Ming-xin Cao, Ya-ping Jiang, Ya-ling Tang,  and Xin-hua Liang
12472-12483
Abstract  |  PDF  |  HTML  |  Order a Reprint

Epigenetic therapy in urologic cancers: an update on clinical trials

Epigenetic therapy in urologic cancers: an update on clinical trials

https://doi.org/10.18632/oncotarget.14226

Inês Faleiro, Ricardo Leão, Alexandra Binnie, Ramon Andrade de Mello, Ana-Teresa Maia,  and Pedro Castelo-Branco
12484-12500
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Guide to detecting epidermal growth factor receptor (EGFR) mutations in ctDNA of patients with advanced non-small-cell lung cancer

Guide to detecting epidermal growth factor receptor (EGFR) mutations in ctDNA of patients with advanced non-small-cell lung cancer

https://doi.org/10.18632/oncotarget.13915

Nicola Normanno, Marc G. Denis, Kenneth S. Thress, Marianne Ratcliffe,  and Martin  Reck
12501-12516
Abstract  |  PDF  |  HTML  |  Order a Reprint

LncRNAs: the bridge linking RNA and colorectal cancer

LncRNAs: the bridge linking RNA and colorectal cancer

https://doi.org/10.18632/oncotarget.13573

Yanfei Yang, Linjie Zhao, Lingzi Lei, Wayne Bond Lau, Bonnie Lau, Qilian Yang, Xiaobing Le, Huiliang Yang, Chenlu Wang, Zhongyue Luo, Yu Xuan, Yi Chen, Xiangbing Deng, Lian Xu, Min Feng, Tao Yi, Xia Zhao, Yuquan Wei,  and Shengtao Zhou
12517-12532
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Corrections

Correction: Pinin interacts with C-terminal binding proteins for RNA alternative splicing and epithelial cell identity of human ovarian cancer cells

Correction: Pinin interacts with C-terminal binding proteins for RNA alternative splicing and epithelial cell identity of human ovarian cancer cells

https://doi.org/10.18632/oncotarget.15321

Yanli Zhang, Jamie Sui-Lam Kwok, Pui-Wah Choi, Minghua Liu, Junzheng Yang, Margit Singh, Shu-Kay Ng, William R. Welch, Michael G. Muto, Stephen KW Tsui, Stephen P. Sugrue, Ross S. Berkowitz,  and Shu-Wing Ng
12533-12533
Correction  |  PDF


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