Oncotarget

Vol 8, No 6

February 7, 2017

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About The Cover

The cover for issue 6 of Oncotarget features Figure 1, 'AMPK-independent mechanisms underlying metformin-induced lifespan extension,' from Pietrocola, et al.

Table of Contents

Editorial

Hypothalamic microRNAs flip the switch for fertility

Hypothalamic microRNAs flip the switch for fertility

https://doi.org/10.18632/oncotarget.14646

Andrea Messina,  and Vincent Prevot
8993-8994
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Editorial: Neuroscience

Parkinson’s disease: no NOP, new hope

Parkinson’s disease: no NOP, new hope

https://doi.org/10.18632/oncotarget.13710

Ludovico Arcuri, Daniela Mercatelli,  and Michele Morari
8995-8996
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Neurons from skin mimic brain holes

Neurons from skin mimic brain holes

https://doi.org/10.18632/oncotarget.13709

Ilya Bezprozvanny,  and Sergey L. Kiselev
8997-8998
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Neurotropic alphaviruses can propagate without capsid

Neurotropic alphaviruses can propagate without capsid

https://doi.org/10.18632/oncotarget.13993

Marta Ruiz-Guillen, Nicola G.A. Abrescia,  and Cristian Smerdou
8999-9000
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α-synuclein and p53 functional interplay in physiopathological contexts

α-synuclein and p53 functional interplay in physiopathological contexts

https://doi.org/10.18632/oncotarget.14385

Cristine Alves da Costa, Eric Duplan,  and Frédéric Checler
9001-9002
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Approaching Alzheimer’s disease from a network level

Approaching Alzheimer’s disease from a network level

https://doi.org/10.18632/oncotarget.14617

Anna K. Gillespie, Emily A. Jones,  and Yadong Huang
9003-9004
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Synthetic microneurotrophins in therapeutics of neurodegeneration

Synthetic microneurotrophins in therapeutics of neurodegeneration

https://doi.org/10.18632/oncotarget.14667

Achille Gravanis, Iosif Pediaditakis,  and Ioannis Charalampopoulos
9005-9006
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15-deoxy-Δ12,14-prostaglandin J2 in neurodegenerative diseases and cancers

15-deoxy-Δ12,14-prostaglandin J2 in neurodegenerative diseases and cancers

https://doi.org/10.18632/oncotarget.14701

Tatsurou Yagami, Yasuhiro Yamamoto,  and Hiromi Koma
9007-9008
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Neurodevelopmental effects of anesthesia and environmental factors

Neurodevelopmental effects of anesthesia and environmental factors

https://doi.org/10.18632/oncotarget.14694

Anatoly E. Martynyuk, Jian-Jun Yang,  and Jia-Qiang Zhang
9009-9010
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Protecting the developing brain by 17β-estradiol

Protecting the developing brain by 17β-estradiol

https://doi.org/10.18632/oncotarget.14819

Julien Pansiot, Jérome Mairesse,  and Olivier Baud
9011-9012
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An insight of rapamycin against cadmium’s neurotoxicity

An insight of rapamycin against cadmium’s neurotoxicity

https://doi.org/10.18632/oncotarget.14872

Chong Xu, Shile Huang,  and Long Chen
9013-9014
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DJ1 at the interface between neuro-degeneration and cancer

DJ1 at the interface between neuro-degeneration and cancer

https://doi.org/10.18632/oncotarget.14889

Johannes Meiser, Alexei Vazquez,  and Karsten Hiller
9015-9016
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Research Perspective: Autophagy

Metformin: a metabolic modulator

Metformin: a metabolic modulator

https://doi.org/10.18632/oncotarget.14794

Federico Pietrocola,  and Guido Kroemer
9017-9020
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Research Papers: Pathology

Lovastatin upregulates microRNA-29b to reduce oxidative stress in rats with multiple cardiovascular risk factors

Lovastatin upregulates microRNA-29b to reduce oxidative stress in rats with multiple cardiovascular risk factors

https://doi.org/10.18632/oncotarget.14462

Fu Wang, Hui Ma, Wen-Jing Liang, Jing-Jing Yang, Xue-Qing Wang, Mei-Rong Shan, Yuan Chen, Min Jia, Ya-Ling Yin, Xue-Ying Sun, Jia-Ning Zhang, Qi-Sheng Peng, Yu-Guo Chen, Li-Ying Liu, Peng Li, Tao Guo,  and Shuang-Xi Wang
9021-9034
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The involvement of endoplasmic reticulum stress response in immune dysfunction of dendritic cells after severe thermal injury in mice

The involvement of endoplasmic reticulum stress response in immune dysfunction of dendritic cells after severe thermal injury in mice

https://doi.org/10.18632/oncotarget.14764

Xiao-Mei Zhu, Ning Dong, Yan-Bo Wang, Qing-Hong Zhang, Yan Yu, Yong-Ming Yao,  and Hua-Ping Liang
9035-9052
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Research Papers: Immunology

Middle east respiratory syndrome corona virus spike glycoprotein suppresses macrophage responses via DPP4-mediated induction of IRAK-M and PPARγ

Middle east respiratory syndrome corona virus spike glycoprotein suppresses macrophage responses via DPP4-mediated induction of IRAK-M and PPARγ

https://doi.org/10.18632/oncotarget.14754

Ahmed A. Al-Qahtani, Konstantina Lyroni, Marina Aznaourova, Melpomeni Tseliou, Mashael R. Al-Anazi, Mohammed N. Al-Ahdal, Saad Alkahtani, George Sourvinos,  and Christos Tsatsanis
9053-9066
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Research Papers

A dose-dependent perturbation in cardiac energy metabolism is linked to radiation-induced ischemic heart disease in Mayak nuclear workers

A dose-dependent perturbation in cardiac energy metabolism is linked to radiation-induced ischemic heart disease in Mayak nuclear workers

https://doi.org/10.18632/oncotarget.10424

Omid Azimzadeh, Tamara Azizova, Juliane Merl-Pham, Vikram Subramanian, Mayur V. Bakshi, Maria Moseeva, Olga Zubkova, Stefanie M. Hauck, Nataša Anastasov, Michael J. Atkinson,  and Soile Tapio
9067-9078
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Loss of RUNX3 expression inhibits bone invasion of oral squamous cell carcinoma

Loss of RUNX3 expression inhibits bone invasion of oral squamous cell carcinoma

https://doi.org/10.18632/oncotarget.14071

Junhee Park, Hyun-Jeong Kim, Ki Rim Kim, Sun Kyoung Lee, Hyungkeun Kim, Kwang-Kyun Park,  and Won-Yoon Chung
9079-9092
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Combined and individual tumor-specific expression of insulin-like growth factor-I receptor, insulin receptor and phospho-insulin-like growth factor-I receptor/insulin receptor in primary breast cancer: Implications for prognosis in different treatment groups

Combined and individual tumor-specific expression of insulin-like growth factor-I receptor, insulin receptor and phospho-insulin-like growth factor-I receptor/insulin receptor in primary breast cancer: Implications for prognosis in different treatment groups

https://doi.org/10.18632/oncotarget.14082

Sofie Björner, Ann H. Rosendahl, Maria Simonsson, Andrea Markkula, Karin Jirström, Signe Borgquist, Carsten Rose, Christian Ingvar,  and Helena Jernström
9093-9107
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SORBS1 suppresses tumor metastasis and improves the sensitivity of cancer to chemotherapy drug

SORBS1 suppresses tumor metastasis and improves the sensitivity of cancer to chemotherapy drug

https://doi.org/10.18632/oncotarget.12851

Lele Song, Renxu Chang, Cheng Dai, Yanjun Wu, Jingyu Guo, Meiyan Qi, Wu Zhou,  and Lixing Zhan
9108-9122
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel histone deacetylase inhibitor, CKD5, has potent anti-cancer effects in glioblastoma

A novel histone deacetylase inhibitor, CKD5, has potent anti-cancer effects in glioblastoma

https://doi.org/10.18632/oncotarget.13265

Seung Ah Choi, Pil Ae Kwak, Chul-Kee Park, Kyu-Chang Wang, Ji Hoon Phi, Ji Yeoun Lee, Chang Sik Lee, Ju-Hee Lee,  and Seung-Ki Kim
9123-9133
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Anti-tumor activity of high-dose EGFR tyrosine kinase inhibitor and sequential docetaxel in wild type EGFR non-small cell lung cancer cell nude mouse xenografts

Anti-tumor activity of high-dose EGFR tyrosine kinase inhibitor and sequential docetaxel in wild type EGFR non-small cell lung cancer cell nude mouse xenografts

https://doi.org/10.18632/oncotarget.13327

Ning Tang, Qianqian Zhang, Shu Fang, Xiao Han,  and Zhehai Wang
9134-9143
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The impact of reproductive life on breast cancer risk in women with family history or BRCA mutation

The impact of reproductive life on breast cancer risk in women with family history or BRCA mutation

https://doi.org/10.18632/oncotarget.13423

Angela Toss, Giovanni Grandi, Angelo Cagnacci, Luigi Marcheselli, Silvia Pavesi, Elisabetta De Matteis, Elisabetta Razzaboni, Chiara Tomasello, Stefano Cascinu,  and Laura Cortesi
9144-9154
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Neuroinflammatory and cognitive consequences of combined radiation and immunotherapy in a novel preclinical model

Neuroinflammatory and cognitive consequences of combined radiation and immunotherapy in a novel preclinical model

https://doi.org/10.18632/oncotarget.13551

Gwendolyn J. McGinnis, David Friedman, Kristina H. Young, Eileen Ruth S. Torres, Charles R. Thomas Jr, Michael J. Gough,  and Jacob Raber
9155-9173
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Targeting the pro-angiogenic forms of VEGF or inhibiting their expression as anti-cancer strategies

Targeting the pro-angiogenic forms of VEGF or inhibiting their expression as anti-cancer strategies

https://doi.org/10.18632/oncotarget.13942

Mélanie Guyot, Caroline Hilmi, Damien Ambrosetti, Marco Merlano, Cristiana Lo Nigro, Jérôme Durivault, Renaud Grépin,  and Gilles Pagès
9174-9188
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mesothelin-targeted immunotoxin RG7787 has synergistic anti-tumor activity when combined with taxanes

Mesothelin-targeted immunotoxin RG7787 has synergistic anti-tumor activity when combined with taxanes

https://doi.org/10.18632/oncotarget.13984

Emily Kolyvas, Michael Rudloff, Marianne Poruchynsky, Rebekah Landsman, Kevin Hollevoet, David Venzon,  and Christine Alewine
9189-9199
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The matricellular protein CYR61 promotes breast cancer lung metastasis by facilitating tumor cell extravasation and suppressing anoikis

The matricellular protein CYR61 promotes breast cancer lung metastasis by facilitating tumor cell extravasation and suppressing anoikis

https://doi.org/10.18632/oncotarget.13677

Yu-Ting Huang, Qiang Lan, Girieca Lorusso, Nathalie Duffey,  and Curzio Rüegg
9200-9215
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MutY-Homolog (MYH) inhibition reduces pancreatic cancer cell growth and increases chemosensitivity

MutY-Homolog (MYH) inhibition reduces pancreatic cancer cell growth and increases chemosensitivity

https://doi.org/10.18632/oncotarget.13985

George Sharbeen, Janet Youkhana, Amanda Mawson, Joshua McCarroll, Andrea p.phillips@unsw.edu.au Nunez, Andrew Biankin, Amber Johns, David Goldstein,  and Phoebe Phillips
9216-9229
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Detection of 14-3-3 sigma (σ) promoter methylation as a noninvasive biomarker using blood samples for breast cancer diagnosis

Detection of 14-3-3 sigma (σ) promoter methylation as a noninvasive biomarker using blood samples for breast cancer diagnosis

https://doi.org/10.18632/oncotarget.13992

Meng Ye, Tao Huang, Ying Ying, Jinyun Li, Ping Yang, Chao Ni, Chongchang Zhou,  and Si Chen
9230-9242
Abstract  |  PDF  |  HTML  |  Order a Reprint

S4S8-RPA phosphorylation as an indicator of cancer progression in oral squamous cell carcinomas

S4S8-RPA phosphorylation as an indicator of cancer progression in oral squamous cell carcinomas

https://doi.org/10.18632/oncotarget.14001

Jeff Rector, Sasha Kapil, Kelly J Treude, Phyllis Kumm, Jason G. Glanzer, Brendan M. Byrne, Shengqin Liu, Lynette M Smith, Dominick J DiMaio, Peter Giannini, Russell B Smith,  and Greg G. Oakley
9243-9250
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer

LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer

https://doi.org/10.18632/oncotarget.14002

Eliza Vakana, Susan Pratt, Wayne Blosser, Michele Dowless, Nicholas Simpson, Xiu-Juan Yuan, Susan Jaken, Jason Manro, Jennifer Stephens, Youyan Zhang, Lysiane Huber, Sheng-Bin Peng,  and Louis F. Stancato
9251-9266
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reducing Smad3/ATF4 was essential for Sirt1 inhibiting ER stress-induced apoptosis in mice brown adipose tissue

Reducing Smad3/ATF4 was essential for Sirt1 inhibiting ER stress-induced apoptosis in mice brown adipose tissue

https://doi.org/10.18632/oncotarget.14035

Zhenjiang Liu, Huihui Gu, Lu Gan, Yatao Xu, Fei Feng, Muhammad Saeed,  and Chao Sun
9267-9279
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress

Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress

https://doi.org/10.18632/oncotarget.14063

Xiangyun Li, Mei Li, Hang Ruan, Wei Qiu, Xiang Xu, Lin Zhang,  and Jian Yu
9280-9292
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression and clinical relevance of epithelial and mesenchymal markers in circulating tumor cells from colorectal cancer

Expression and clinical relevance of epithelial and mesenchymal markers in circulating tumor cells from colorectal cancer

https://doi.org/10.18632/oncotarget.14065

Ren Zhao, Zhen Cai, Sheng Li, Yong Cheng, Hua Gao, Fang Liu, Shiyang Wu, Suyan Liu, Yan Dong, Lei Zheng, Wenbin Zhang, Xiaojun Wu,  and Xueqing Yao
9293-9302
Abstract  |  PDF  |  HTML  |  Order a Reprint

Bafilomycin A1 triggers proliferative potential of senescent cancer cells in vitro and in NOD/SCID mice

Bafilomycin A1 triggers proliferative potential of senescent cancer cells in vitro and in NOD/SCID mice

https://doi.org/10.18632/oncotarget.14066

Halina Was, Kamila Barszcz, Joanna Czarnecka, Agata Kowalczyk, Tytus Bernas, Ewelina Uzarowska, Paulina Koza, Agata Klejman, Katarzyna Piwocka, Bozena Kaminska,  and Eva Sikora
9303-9322
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Livin/BIRC7 expression as malignancy marker in adrenocortical tumors

Livin/BIRC7 expression as malignancy marker in adrenocortical tumors

https://doi.org/10.18632/oncotarget.14067

Barbara Altieri, Silviu Sbiera, Silvia Della Casa, Isabel Weigand, Vanessa Wild, Sonja Steinhauer, Guido Fadda, Arkadius Kocot, Michaela Bekteshi, Egle M. Mambretti, Andreas Rosenwald, Alfredo Pontecorvi, Martin Fassnacht,  and Cristina L. Ronchi
9323-9338
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Antagonizing functions of BARD1 and its alternatively spliced variant BARD1δ in telomere stability

Antagonizing functions of BARD1 and its alternatively spliced variant BARD1δ in telomere stability

https://doi.org/10.18632/oncotarget.14068

Maxim Pilyugin, Pierre-Alain André, Magdalena Ratajska, Alina Kuzniacka, Janusz Limon, Benjamin B. Tournier, Julien Colas, Geoff Laurent,  and Irmgard Irminger-Finger
9339-9353
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value and clinicopathological features of PD-1/PD-L1 expression with mismatch repair status and desmoplastic stroma in Chinese patients with pancreatic cancer

Prognostic value and clinicopathological features of PD-1/PD-L1 expression with mismatch repair status and desmoplastic stroma in Chinese patients with pancreatic cancer

https://doi.org/10.18632/oncotarget.14069

Yu Wang, Jiacheng Lin, Jiujie Cui, Ting Han, Feng Jiao, Zhuo Meng,  and Liwei Wang
9354-9365
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Vamorolone, a dissociative steroidal compound, reduces pro-inflammatory cytokine expression in glioma cells and increases activity and survival in a murine model of cortical tumor

Vamorolone, a dissociative steroidal compound, reduces pro-inflammatory cytokine expression in glioma cells and increases activity and survival in a murine model of cortical tumor

https://doi.org/10.18632/oncotarget.14070

Elizabeth Wells, Madhuri Kambhampati, Jesse M. Damsker, Heather Gordish-Dressman, Sridevi Yadavilli, Oren J. Becher, Jamila Gittens, Mojca Stampar, Roger J. Packer,  and Javad Nazarian
9366-9374
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeted delivery of CRISPR/Cas9 to prostate cancer by modified gRNA using a flexible aptamer-cationic liposome

Targeted delivery of CRISPR/Cas9 to prostate cancer by modified gRNA using a flexible aptamer-cationic liposome

https://doi.org/10.18632/oncotarget.14072

Shuai Zhen, Yoichiro Takahashi, Shunichi Narita, Yi-Chen Yang,  and Xu Li
9375-9387
Abstract  |  PDF  |  HTML  |  Order a Reprint

Pharmacogenetic analysis of high-dose methotrexate treatment in children with osteosarcoma

Pharmacogenetic analysis of high-dose methotrexate treatment in children with osteosarcoma

https://doi.org/10.18632/oncotarget.11543

Marta Hegyi, Adam Arany, Agnes F. Semsei, Katalin Csordas, Oliver Eipel, Andras Gezsi, Nora Kutszegi, Monika Csoka, Judit Muller, Daniel J. Erdelyi, Peter Antal, Csaba Szalai,  and Gabor T. Kovacs
9388-9398
Abstract  |  PDF  |  HTML  |  Order a Reprint

Resveratrol-induced antinociception is involved in calcium channels and calcium/caffeine-sensitive pools

Resveratrol-induced antinociception is involved in calcium channels and calcium/caffeine-sensitive pools

https://doi.org/10.18632/oncotarget.14090

Xiaoyu Pan, Jiechun Chen, Weijie Wang, Ling Chen, Lin Wang, Quan Ma, Jianbo Zhang, Lichao Chen, Gang Wang, Meixi Zhang, Hao Wu,  and Ruochuan Cheng
9399-9409
Abstract  |  PDF  |  HTML  |  Order a Reprint

Overendocytosis of superparamagnetic iron oxide particles increases apoptosis and triggers autophagic cell death in human osteosarcoma cell under a spinning magnetic field

Overendocytosis of superparamagnetic iron oxide particles increases apoptosis and triggers autophagic cell death in human osteosarcoma cell under a spinning magnetic field

https://doi.org/10.18632/oncotarget.14114

Shaohua Du, Jingxiong Li, Chonghua Du, Zhongming Huang, Guangnan Chen,  and Weiqi Yan
9410-9424
Abstract  |  PDF  |  HTML  |  Order a Reprint

Gene expression profiling of tumor-initiating stem cells from mouse Krebs-2 carcinoma using a novel marker of poorly differentiated cells

Gene expression profiling of tumor-initiating stem cells from mouse Krebs-2 carcinoma using a novel marker of poorly differentiated cells

https://doi.org/10.18632/oncotarget.14116

Ekaterina A. Potter, Evgenia V. Dolgova, Anastasia S. Proskurina, Yaroslav R. Efremov, Alexandra M. Minkevich, Aleksey S. Rozanov, Sergey E. Peltek, Valeriy P. Nikolin, Nelly A. Popova, Igor A. Seledtsov, Vladimir V. Molodtsov, Evgeniy L. Zavyalov, Oleg S. Taranov, Sergey I. Baiborodin, Alexander A. Ostanin, Elena R. Chernykh, Nikolay A. Kolchanov,  and Sergey S. Bogachev
9425-9441
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nuclear overexpression of the overexpressed in lung cancer 1 predicts worse prognosis in gastric adenocarcinoma

Nuclear overexpression of the overexpressed in lung cancer 1 predicts worse prognosis in gastric adenocarcinoma

https://doi.org/10.18632/oncotarget.14217

Jue Wang, Hongchang Shen, Guobin Fu, Dandan Zhao,  and Weibo Wang
9442-9450
Abstract  |  PDF  |  HTML  |  Order a Reprint

Long non-coding RNA AK058003, as a precursor of miR-15a, interacts with HuR to inhibit the expression of γ-synuclein in hepatocellular carcinoma cells

Long non-coding RNA AK058003, as a precursor of miR-15a, interacts with HuR to inhibit the expression of γ-synuclein in hepatocellular carcinoma cells

https://doi.org/10.18632/oncotarget.14276

Xiaoqin He, Yongfa Zheng, Yuefeng Zhang, Yuanyuan Gan, Yujie Zhou, Huilin Liang, Dongcheng Wu, Wei Ge, Junjian Deng,  and Ximing Xu
9451-9465
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of mTOR as a primary resistance factor of the IAP antagonist AT406 in hepatocellular carcinoma cells

Identification of mTOR as a primary resistance factor of the IAP antagonist AT406 in hepatocellular carcinoma cells

https://doi.org/10.18632/oncotarget.14326

Mao-Chuan Zhen, Fu-Qiang Wang, Shao-Feng Wu, Yi-Lin Zhao, Ping-Guo Liu,  and Zhen-Yu Yin
9466-9475
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

V-ATPase inhibition increases cancer cell stiffness and blocks membrane related Ras signaling - a new option for HCC therapy

V-ATPase inhibition increases cancer cell stiffness and blocks membrane related Ras signaling - a new option for HCC therapy

https://doi.org/10.18632/oncotarget.14339

Karin Bartel, Maria Winzi, Melanie Ulrich, Andreas Koeberle, Dirk Menche, Oliver Werz, Rolf Müller, Jochen Guck, Angelika M. Vollmar,  and Karin von Schwarzenberg
9476-9487
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Chimeric antigen receptor-modified T Cells inhibit the growth and metastases of established tissue factor-positive tumors in NOG mice

Chimeric antigen receptor-modified T Cells inhibit the growth and metastases of established tissue factor-positive tumors in NOG mice

https://doi.org/10.18632/oncotarget.14367

Qing Zhang, Haiyu Wang, Huizhong Li, Jinjing Xu, Kang Tian, Jie Yang, Zheng Lu,  and Junnian Zheng
9488-9499
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5α-reductase and extracellular signal-regulated kinase

Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5α-reductase and extracellular signal-regulated kinase

https://doi.org/10.18632/oncotarget.13430

Dong-Hyun Youn, Jinbong Park, Hye-Lin Kim, Yunu Jung, JongWook Kang, Mi-Young Jeong, Gautam Sethi, Kwang Seok Ahn,  and Jae-Young Um
9500-9512
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LMO2 promotes tumor cell invasion and metastasis in basal-type breast cancer by altering actin cytoskeleton remodeling

LMO2 promotes tumor cell invasion and metastasis in basal-type breast cancer by altering actin cytoskeleton remodeling

https://doi.org/10.18632/oncotarget.13434

Ye Liu, Zhaoyang Wang, Di Huang, Chao Wu, Huihui Li, Xin Zhang, Bin Meng, Zongjin Li, Tianhui Zhu, Shuang Yang,  and Wei Sun
9513-9524
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of laryngeal cancer prognostic biomarkers using an inflammatory gene-related, competitive endogenous RNA network

Identification of laryngeal cancer prognostic biomarkers using an inflammatory gene-related, competitive endogenous RNA network

https://doi.org/10.18632/oncotarget.13627

Qun He, Linli Tian, Hao Jiang, Jiarui Zhang, Qiang Li, Yanan Sun, Jiannan Zhao, Huijun Li,  and Ming Liu
9525-9534
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HIF-1α induces the epithelial-mesenchymal transition in gastric cancer stem cells through the Snail pathway

HIF-1α induces the epithelial-mesenchymal transition in gastric cancer stem cells through the Snail pathway

https://doi.org/10.18632/oncotarget.14484

Shi-wei Yang, Zhi-gang Zhang, Ying-xue Hao, Yong-liang Zhao, Feng Qian, Yan Shi, Ping-ang Li, Chun-yang Liu,  and Pei-wu Yu
9535-9545
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Systematic evaluation of supervised classifiers for fecal microbiota-based prediction of colorectal cancer

Systematic evaluation of supervised classifiers for fecal microbiota-based prediction of colorectal cancer

https://doi.org/10.18632/oncotarget.14488

Luoyan Ai, Haiying Tian, Zhaofei Chen, Huimin Chen, Jie Xu,  and Jing-Yuan Fang
9546-9556
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

EGF induces epithelial-mesenchymal transition and cancer stem-like cell properties in human oral cancer cells via promoting Warburg effect

EGF induces epithelial-mesenchymal transition and cancer stem-like cell properties in human oral cancer cells via promoting Warburg effect

https://doi.org/10.18632/oncotarget.13771

Qilin Xu, Qunzhou Zhang, Yasutaka Ishida, Souren Hajjar, Xudong Tang, Haoran Shi, Chi V. Dang,  and Anh D. Le
9557-9571
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel non-canonical Wnt signature for prostate cancer aggressiveness

A novel non-canonical Wnt signature for prostate cancer aggressiveness

https://doi.org/10.18632/oncotarget.14161

Elise Sandsmark, Ailin Falkmo Hansen, Kirsten M. Selnæs, Helena Bertilsson, Anna M. Bofin, Alan J. Wright, Trond Viset, Elin Richardsen, Finn Drabløs, Tone F. Bathen, May-Britt Tessem,  and Morten B. Rye
9572-9586
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Association between metformin use and mortality in patients with type 2 diabetes mellitus and localized resectable pancreatic cancer: a nationwide population-based study in korea

Association between metformin use and mortality in patients with type 2 diabetes mellitus and localized resectable pancreatic cancer: a nationwide population-based study in korea

https://doi.org/10.18632/oncotarget.14525

Won Il Jang, Mi-Sook Kim, Shin Hee Kang, Ae Jung Jo, Yun Jung Kim, Ha Jin Tchoe, Chan Mi Park, Hyo Jeong Kim, Jin A Choi, Hyung Jin Choi, Eun-Kyung Paik, Young Seok Seo, Hyung Jun Yoo, Jin-Kyu Kang, Chul Ju Han, Yeon Ju Kim, Sang Beom Kim,  and Min Jung Ko
9587-9596
Abstract  |  PDF  |  HTML  |  Order a Reprint

Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer

Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer

https://doi.org/10.18632/oncotarget.14162

Murilo Vieira Geraldo, Helder Imoto Nakaya,  and Edna Teruko Kimura
9597-9607
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The tumor microenvironment promotes cancer progression and cell migration

The tumor microenvironment promotes cancer progression and cell migration

https://doi.org/10.18632/oncotarget.14155

Viviana Salvatore, Gabriella Teti, Stefano Focaroli, Maria Carla Mazzotti, Antonio Mazzotti,  and Mirella Falconi
9608-9616
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Androgen receptor transcriptionally regulates semaphorin 3C in a GATA2-dependent manner

Androgen receptor transcriptionally regulates semaphorin 3C in a GATA2-dependent manner

https://doi.org/10.18632/oncotarget.14168

Kevin J Tam, Kush Dalal, Michael Hsing, Chi Wing Cheng, Shahram Khosravi, Parvin Yenki, Charan Tse, James W Peacock, Aishwariya Sharma, Yan Ting Chiang, Yuzhuo Wang, Artem Cherkasov, Paul S Rennie, Martin E Gleave,  and Christopher J Ong
9617-9633
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of long non-coding RNA UCA1 by CRISPR/Cas9 attenuated malignant phenotypes of bladder cancer

Inhibition of long non-coding RNA UCA1 by CRISPR/Cas9 attenuated malignant phenotypes of bladder cancer

https://doi.org/10.18632/oncotarget.14176

Shuai Zhen, Ling Hua, Yun-Hui Liu, Xiao-Min Sun, Meng-Meng Jiang, Wei Chen, Le Zhao,  and Xu Li
9634-9646
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Histone deacetylase inhibitor SAHA mediates mast cell death and epigenetic silencing of constitutively active D816V KIT in systemic mastocytosis

Histone deacetylase inhibitor SAHA mediates mast cell death and epigenetic silencing of constitutively active D816V KIT in systemic mastocytosis

https://doi.org/10.18632/oncotarget.14181

Katarina Lyberg, Hani Abdulkadir Ali, Jennine Grootens, Matilda Kjellander, Malin Tirfing, Michel Arock, Hans Hägglund, Gunnar Nilsson,  and Johanna Ungerstedt
9647-9659
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Diagnostic accuracy of urine HE4 in patients with ovarian cancer: a meta-analysis

Diagnostic accuracy of urine HE4 in patients with ovarian cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.14173

Meng-Meng Jia, Jie Deng, Xiao-lin Cheng, Zhen Yan, Qing-Chun Li, Ying-Ying Xing, Dong-Mei Fan,  and Xiao-Yu Tian
9660-9671
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Increased risk of poor survival in ovarian cancer patients with high expression of SNAI2 and lymphovascular space invasion

Increased risk of poor survival in ovarian cancer patients with high expression of SNAI2 and lymphovascular space invasion

https://doi.org/10.18632/oncotarget.14192

Jun Li, Shufen Li, Ruifang Chen,  and Xin Lu
9672-9685
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Elevated plasma interleukin-37 playing an important role in acute coronary syndrome through suppression of ROCK activation

Elevated plasma interleukin-37 playing an important role in acute coronary syndrome through suppression of ROCK activation

https://doi.org/10.18632/oncotarget.14195

Tengyu Yang, Fang Fang, Yawen Chen, Jing Ma, Zhaowen Xiao, Songfeng Zou, Na Zheng, Dewen Yan, Songyan Liao, Shaoyuan Chen, Hongchen Fang, Chekmen Yu, Jie Liu,  and Ming Dong
9686-9695
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Aneuploidy related transcriptional changes in endometrial cancer link low expression of chromosome 15q genes to poor survival

Aneuploidy related transcriptional changes in endometrial cancer link low expression of chromosome 15q genes to poor survival

https://doi.org/10.18632/oncotarget.14201

Karen Klepsland Mauland, Elisabeth Wik, Erling A. Hoivik, Kanthida Kusonmano, Mari Kyllesø Halle, Anna Berg, Hans Kristian Haugland, Anne Margrete Øyan, Karl-Henning Kalland, Ingunn Marie Stefansson, Lars A. Akslen, Camilla Krakstad, Jone Trovik, Henrica Maria Johanna Werner,  and Helga Birgitte Salvesen
9696-9707
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value of expression of nuclear factor kappa-B/p65 in non-GCB DLBCL patients

Prognostic value of expression of nuclear factor kappa-B/p65 in non-GCB DLBCL patients

https://doi.org/10.18632/oncotarget.14182

Jing Wang, Min Zhou, Qi-Guo Zhang, Jingyan Xu, Tong Lin, Rong-Fu Zhou, Juan Li, Yong-Gong Yang, Bing Chen,  and Jian Ouyang
9708-9716
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The expression of Nectin-4 on the surface of ovarian cancer cells alters their ability to adhere, migrate, aggregate, and proliferate

The expression of Nectin-4 on the surface of ovarian cancer cells alters their ability to adhere, migrate, aggregate, and proliferate

https://doi.org/10.18632/oncotarget.14206

Kristin L.M Boylan, Petra C Buchanan, Rory D Manion, Dip M Shukla, Kelly Braumberger, Cody Bruggemeyer,  and Amy P.N Skubitz
9717-9738
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Tumor-associated macrophages promote prostate cancer migration through activation of the CCL22–CCR4 axis

Tumor-associated macrophages promote prostate cancer migration through activation of the CCL22–CCR4 axis

https://doi.org/10.18632/oncotarget.14185

Aerken Maolake, Kouji Izumi, Kazuyoshi Shigehara, Ariunbold Natsagdorj, Hiroaki Iwamoto, Suguru Kadomoto, Yuta Takezawa, Kazuaki Machioka, Kazutaka Narimoto, Mikio Namiki, Wen-Jye Lin, Guzailinuer Wufuer,  and Atsushi Mizokami
9739-9751
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Multicellular spheroids from normal and neoplastic thyroid tissues as a suitable model to test the effects of multikinase inhibitors

Multicellular spheroids from normal and neoplastic thyroid tissues as a suitable model to test the effects of multikinase inhibitors

https://doi.org/10.18632/oncotarget.14187

Valentina Cirello, Valentina Vaira, Elisa Stellaria Grassi, Valeria Vezzoli, Dario Ricca, Carla Colombo, Silvano Bosari, Leonardo Vicentini, Luca Persani, Stefano Ferrero,  and Laura Fugazzola
9752-9766
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The Netrin-4/ Neogenin-1 axis promotes neuroblastoma cell survival and migration

The Netrin-4/ Neogenin-1 axis promotes neuroblastoma cell survival and migration

https://doi.org/10.18632/oncotarget.14213

Andrea A. Villanueva, Paulina Falcón, Natalie Espinoza, Luis Solano R., Luis A. Milla, Esther Hernandez-SanMiguel, Vicente A. Torres, Pilar Sanchez-Gomez,  and Verónica Palma
9767-9782
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Loss of FOXN3 in colon cancer activates beta-catenin/TCF signaling and promotes the growth and migration of cancer cells

Loss of FOXN3 in colon cancer activates beta-catenin/TCF signaling and promotes the growth and migration of cancer cells

https://doi.org/10.18632/oncotarget.14189

Yuedi Dai, Meixing Wang, Haixia Wu, Mi Xiao, Houbao Liu,  and Dexiang Zhang
9783-9793
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Homeobox A11 hypermethylation indicates unfavorable prognosis in breast cancer

Homeobox A11 hypermethylation indicates unfavorable prognosis in breast cancer

https://doi.org/10.18632/oncotarget.14216

Bingshu Xia, Ming Shan, Ji Wang, Zhenbin Zhong, Jingshu Geng, Xiaohui He, Tung Vu, Dekai Zhang,  and Da Pang
9794-9805
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NFKB1 -94insertion/deletion ATTG polymorphism and cancer risk: Evidence from 50 case-control studies

NFKB1 -94insertion/deletion ATTG polymorphism and cancer risk: Evidence from 50 case-control studies

https://doi.org/10.18632/oncotarget.14190

Wen Fu, Zhen-Jian Zhuo, Yung-Chang Chen, Jinhong Zhu, Zhang Zhao, Wei Jia, Jin-Hua Hu, Kai Fu, Shi-Bo Zhu, Jing He,  and Guo-Chang Liu
9806-9822
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Noncalcemic 20-hydroxyvitamin D3 inhibits human melanoma growth in in vitro and in vivo models

Noncalcemic 20-hydroxyvitamin D3 inhibits human melanoma growth in in vitro and in vivo models

https://doi.org/10.18632/oncotarget.14193

Cezary Skobowiat, Allen S.W. Oak, Tae-Kang Kim, Chuan He Yang, Lawrence M. Pfeffer, Robert C. Tuckey,  and Andrzej T. Slominski
9823-9834
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SETMAR isoforms in glioblastoma: A matter of protein stability

SETMAR isoforms in glioblastoma: A matter of protein stability

https://doi.org/10.18632/oncotarget.14218

Audrey Dussaussois-Montagne, Jérôme Jaillet, Laetitia Babin, Pierre Verrelle, Lucie Karayan-Tapon, Sylvaine Renault, Cécilia Rousselot-Denis, Ilyess Zemmoura,  and Corinne Augé-Gouillou
9835-9848
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic polymorphisms in the telomere length-related gene ACYP2 are associated with the risk of colorectal cancer in a Chinese Han population

Genetic polymorphisms in the telomere length-related gene ACYP2 are associated with the risk of colorectal cancer in a Chinese Han population

https://doi.org/10.18632/oncotarget.14219

Fang Liu, Zhongguo Zhang, Yong Zhang, Yue Chen, Xiaoyu Yang, Jibin Li,  and Jiaxing Zhao
9849-9857
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Phosphorylation of EB1 regulates the recruitment of CLIP-170 and p150glued to the plus ends of astral microtubules

Phosphorylation of EB1 regulates the recruitment of CLIP-170 and p150glued to the plus ends of astral microtubules

https://doi.org/10.18632/oncotarget.14222

Jie Ran, Youguang Luo, Yijun Zhang, Yang Yang, Miao Chen, Min Liu, Dengwen Li,  and Jun Zhou
9858-9867
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Targeting cancer stem cell propagation with palbociclib, a CDK4/6 inhibitor: Telomerase drives tumor cell heterogeneity

Targeting cancer stem cell propagation with palbociclib, a CDK4/6 inhibitor: Telomerase drives tumor cell heterogeneity

https://doi.org/10.18632/oncotarget.14196

Gloria Bonuccelli, Maria Peiris-Pages, Bela Ozsvari, Ubaldo E. Martinez-Outschoorn, Federica Sotgia,  and Michael P. Lisanti
9868-9884
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Hypoxia-inducible factor prolyl hydroxylase 2 (PHD2) is a direct regulator of epidermal growth factor receptor (EGFR) signaling in breast cancer

Hypoxia-inducible factor prolyl hydroxylase 2 (PHD2) is a direct regulator of epidermal growth factor receptor (EGFR) signaling in breast cancer

https://doi.org/10.18632/oncotarget.14241

Nina Kozlova, Marieke Wottawa, Dörthe Magdalena Katschinski, Glen Kristiansen,  and Thomas Kietzmann
9885-9898
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Visualization of exosome-mediated miR-210 transfer from hypoxic tumor cells

Visualization of exosome-mediated miR-210 transfer from hypoxic tumor cells

https://doi.org/10.18632/oncotarget.14247

Kyung Oh Jung, Hyewon Youn, Chul-Hee Lee, Keon Wook Kang,  and June-Key Chung
9899-9910
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-21 as prognostic biomarker in head and neck squamous cell carcinoma patients undergoing an organ preservation protocol

MiR-21 as prognostic biomarker in head and neck squamous cell carcinoma patients undergoing an organ preservation protocol

https://doi.org/10.18632/oncotarget.14253

Lidia Maria Rebolho Batista Arantes, Ana Carolina Laus, Matias Eliseo Melendez, Ana Carolina de Carvalho, Bruna Pereira Sorroche, Pedro Rafael Martins De Marchi, Adriane Feijó Evangelista, Cristovam Scapulatempo-Neto, Luciano de Souza Viana,  and André Lopes Carvalho
9911-9921
Abstract  |  PDF  |  HTML  |  Order a Reprint

Antagonism of Interleukin-17A ameliorates experimental hepatic fibrosis by restoring the IL-10/STAT3-suppressed autophagy in hepatocytes

Antagonism of Interleukin-17A ameliorates experimental hepatic fibrosis by restoring the IL-10/STAT3-suppressed autophagy in hepatocytes

https://doi.org/10.18632/oncotarget.14266

Xiao-Wei Zhang, Su Mi, Zhe Li, Ji-Chao Zhou, Jing Xie, Fang Hua, Ke Li, Bing Cui, Xiao-Xi Lv, Jiao-Jiao Yu,  and Zhuo-Wei Hu
9922-9934
Abstract  |  PDF  |  HTML  |  Order a Reprint

Risk assessment models to evaluate the necessity of prostate biopsies in North Chinese patients with 4-50 ng/mL PSA

Risk assessment models to evaluate the necessity of prostate biopsies in North Chinese patients with 4-50 ng/mL PSA

https://doi.org/10.18632/oncotarget.14214

Jing Zhao, Shuai Liu, Dexuan Gao, Sentai Ding, Zhihong Niu, Hui Zhang, Zhilong Huang, Juhui Qiu, Qing Li, Ning Li, Fang Xie, Jilei Cui,  and Jiaju Lu
9935-9946
Abstract  |  PDF  |  HTML  |  Order a Reprint

Nutrient-induced FNIP degradation by SCFβ-TRCP regulates FLCN complex localization and promotes renal cancer progression

Nutrient-induced FNIP degradation by SCFβ-TRCP regulates FLCN complex localization and promotes renal cancer progression

https://doi.org/10.18632/oncotarget.14221

Katsuyuki Nagashima, Hidefumi Fukushima, Kouhei Shimizu, Aya Yamada, Masumi Hidaka, Hisashi Hasumi, Tetsuro Ikebe, Satoshi Fukumoto, Koji Okabe,  and Hiroyuki Inuzuka
9947-9960
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PDGF-D promotes cell growth, aggressiveness, angiogenesis and EMT transformation of colorectal cancer by activation of Notch1/Twist1 pathway

PDGF-D promotes cell growth, aggressiveness, angiogenesis and EMT transformation of colorectal cancer by activation of Notch1/Twist1 pathway

https://doi.org/10.18632/oncotarget.14283

Jinhuang Chen, Wenzheng Yuan, Liang Wu, Qiang Tang, Qinghua Xia, Jintong Ji, Zhengyi Liu, Zhijun Ma, Zili Zhou, Yifeng Cheng,  and Xiaogang Shu
9961-9973
Abstract  |  PDF  |  HTML  |  Order a Reprint

TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress

TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress

https://doi.org/10.18632/oncotarget.14285

Florent Dufour, Thibault Rattier, Andrei Alexandru Constantinescu, Luciana Zischler, Aymeric Morlé, Hazem Ben Mabrouk, Etienne Humblin, Guillaume Jacquemin, Eva Szegezdi, Fabien Delacote, Naziha Marrakchi, Gilles Guichard, Catherine Pellat-Deceunynck, Pierre Vacher, Patrick Legembre, Carmen Garrido,  and Olivier Micheau
9974-9985
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sulodexide pretreatment attenuates renal ischemia-reperfusion injury in rats

Sulodexide pretreatment attenuates renal ischemia-reperfusion injury in rats

https://doi.org/10.18632/oncotarget.14309

Jianyong Yin, Weibin Chen, Fenfen Ma, Zeyuan Lu, Rui Wu, Guangyuan Zhang, Niansong Wang,  and Feng Wang
9986-9995
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Cost-effectiveness of gefitinib, icotinib, and pemetrexed-based chemotherapy as first-line treatments for advanced non-small cell lung cancer in China

Cost-effectiveness of gefitinib, icotinib, and pemetrexed-based chemotherapy as first-line treatments for advanced non-small cell lung cancer in China

https://doi.org/10.18632/oncotarget.14310

Shun Lu, Ming Ye, Lieming Ding, Fenlai Tan, Jie Fu,  and Bin Wu
9996-10006
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The RNA-binding protein ESRP1 promotes human colorectal cancer progression

The RNA-binding protein ESRP1 promotes human colorectal cancer progression

https://doi.org/10.18632/oncotarget.14318

Sharmila Fagoonee, Gabriele Picco, Francesca Orso, Arrigo Arrigoni, Dario L. Longo, Marco Forni, Irene Scarfò, Adele Cassenti, Roberto Piva, Paola Cassoni, Lorenzo Silengo, Emanuela Tolosano, Silvio Aime, Daniela Taverna, Pier Paolo Pandolfi, Mara Brancaccio, Enzo Medico,  and Fiorella Altruda
10007-10024
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hsp90 N- and C-terminal double inhibition synergistically suppresses Bcr-Abl-positive human leukemia cells

Hsp90 N- and C-terminal double inhibition synergistically suppresses Bcr-Abl-positive human leukemia cells

https://doi.org/10.18632/oncotarget.14324

Chun Chen, Yingting Zhuang, Xianling Chen, Xiaole Chen, Ding Li, Yingjuan Fan, Jianhua Xu, Yuanzhong Chen,  and Lixian Wu
10025-10036
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Abnormal expression of TGF-beta type II receptor isoforms contributes to acute myeloid leukemia

Abnormal expression of TGF-beta type II receptor isoforms contributes to acute myeloid leukemia

https://doi.org/10.18632/oncotarget.14325

Yong Wu, Min Su, ShuX Zhang, Yu Cheng, Xiao Y. Liao, Bao Y. Lin,  and Yuan Z. Chen
10037-10049
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Spermatogonial stem cells and progenitors are refractory to reprogramming to pluripotency by the transcription factors Oct3/4, c-Myc, Sox2 and Klf4

Spermatogonial stem cells and progenitors are refractory to reprogramming to pluripotency by the transcription factors Oct3/4, c-Myc, Sox2 and Klf4

https://doi.org/10.18632/oncotarget.14327

Sébastien Corbineau, Bruno Lassalle, Maelle Givelet, Inès Souissi-Sarahoui, Virginie Firlej, Paul Henri Romeo, Isabelle Allemand, Lydia Riou,  and Pierre Fouchet
10050-10063
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Single nucleotide polymorphisms in ZNRD1-AS1 increase cancer risk in an Asian population

Single nucleotide polymorphisms in ZNRD1-AS1 increase cancer risk in an Asian population

https://doi.org/10.18632/oncotarget.14334

Ping-Yu Wang, Jing-Hua Li, Yue-Mei Liu, Qing Lv, Ning Xie, Han-Han Zhang,  and Shu-Yang Xie
10064-10070
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cytotoxic lanostane-type triterpenoids from the fruiting bodies of Ganoderma lucidum and their structure–activity relationships

Cytotoxic lanostane-type triterpenoids from the fruiting bodies of Ganoderma lucidum and their structure–activity relationships

https://doi.org/10.18632/oncotarget.14336

Shaodan Chen, Xiangmin Li, Tianqiao Yong, Zhanggen Wang, Jiyan Su, Chunwei Jiao, Yizhen Xie,  and Burton B. Yang
10071-10084
Abstract  |  PDF  |  HTML  |  Order a Reprint

ITPR3 gene haplotype is associated with cervical squamous cell carcinoma risk in Taiwanese women

ITPR3 gene haplotype is associated with cervical squamous cell carcinoma risk in Taiwanese women

https://doi.org/10.18632/oncotarget.14341

Yuh-Cheng Yang, Tzu-Yang Chang, Tze-Chien Chen, Wen-Shan Lin, Shih-Chuan Chang,  and Yann-Jinn Lee
10085-10090
Abstract  |  PDF  |  HTML  |  Order a Reprint

A novel splice variant of the protein tyrosine phosphatase PTPRJ that encodes for a soluble protein involved in angiogenesis

A novel splice variant of the protein tyrosine phosphatase PTPRJ that encodes for a soluble protein involved in angiogenesis

https://doi.org/10.18632/oncotarget.14350

Anna Bilotta, Vincenzo Dattilo, Sabrina D'Agostino, Stefania Belviso, Stefania Scalise, Mariaconcetta Bilotta, Eugenio Gaudio, Francesco Paduano, Nicola Perrotti, Tullio Florio, Alfredo Fusco, Rodolfo Iuliano,  and Francesco Trapasso
10091-10102
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Antidepressant effect of recombinant NT4-NAP/AAV on social isolated mice through intranasal route

Antidepressant effect of recombinant NT4-NAP/AAV on social isolated mice through intranasal route

https://doi.org/10.18632/oncotarget.14356

Fei Liu, You-ping Liu, Gang Lei, Peng Liu, Zheng Chu, Cheng-ge Gao,  and Yong-hui Dang
10103-10113
Abstract  |  PDF  |  HTML  |  Order a Reprint

BRCA1-IRIS overexpression promotes and maintains the tumor initiating phenotype: implications for triple negative breast cancer early lesions

BRCA1-IRIS overexpression promotes and maintains the tumor initiating phenotype: implications for triple negative breast cancer early lesions

https://doi.org/10.18632/oncotarget.14357

Abhilasha Sinha, Bibbin T. Paul, Lisa M. Sullivan, Hillary Sims, Ahmed El Bastawisy, Hend F. Yousef, Abdel-Rahman N. Zekri, Abeer A. Bahnassy,  and Wael M. ElShaym
10114-10135
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Retrospective analysis of 85 cases of intermediate-risk gastrointestinal stromal tumor

Retrospective analysis of 85 cases of intermediate-risk gastrointestinal stromal tumor

https://doi.org/10.18632/oncotarget.14359

Yang Fu, He Hao, Luwei Guo, Ge Yang,  and Xiefu Zhang
10136-10144
Abstract  |  PDF  |  HTML  |  Order a Reprint

Angiomotin regulates prostate cancer cell proliferation by signaling through the Hippo-YAP pathway

Angiomotin regulates prostate cancer cell proliferation by signaling through the Hippo-YAP pathway

https://doi.org/10.18632/oncotarget.14358

Hao Zeng, Angelica Ortiz, Peng-fei Shen, Chien-Jui Cheng, Yu-Chen Lee, Guoyu Yu, Song-Chang Lin, Chad J. Creighton, Li-Yuan Yu-Lee,  and Sue-Hwa Lin
10145-10160
Abstract  |  PDF  |  HTML  |  Order a Reprint

Protective effect of tanshinone IIA against cardiac hypertrophy in spontaneously hypertensive rats through inhibiting the Cys-C/Wnt signaling pathway

Protective effect of tanshinone IIA against cardiac hypertrophy in spontaneously hypertensive rats through inhibiting the Cys-C/Wnt signaling pathway

https://doi.org/10.18632/oncotarget.14328

Jun Feng, Hua-Wen Chen, Li-Juan Pi, Jin Wang,  and Da-Qian Zhan
10161-10170
Abstract  |  PDF  |  HTML  |  Order a Reprint

Competing endogenous RNA network analysis identifies critical genes among the different breast cancer subtypes

Competing endogenous RNA network analysis identifies critical genes among the different breast cancer subtypes

https://doi.org/10.18632/oncotarget.14361

Juan Chen, Juan Xu, Yongsheng Li, Jinwen Zhang, Hong Chen, Jianping Lu, Zishan Wang, Xueying Zhao, Kang Xu, Yixue Li, Xia Li,  and Yan Zhang
10171-10184
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

COX-2/mPGES-1/PGE2 cascade activation mediates uric acid-induced mesangial cell proliferation

COX-2/mPGES-1/PGE2 cascade activation mediates uric acid-induced mesangial cell proliferation

https://doi.org/10.18632/oncotarget.14363

Shuzhen Li, Zhenzhen Sun, Yue Zhang, Yuan Ruan, Qiuxia Chen, Wei Gong, Jing Yu, Weiwei Xia, John Ci-Jiang He, Songming Huang, Aihua Zhang, Guixia Ding,  and Zhanjun Jia
10185-10198
Abstract  |  PDF  |  HTML  |  Order a Reprint

VHL missense mutations in the p53 binding domain show different effects on p53 signaling and HIFα degradation in clear cell renal cell carcinoma

VHL missense mutations in the p53 binding domain show different effects on p53 signaling and HIFα degradation in clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.14372

Caroline Fanja Razafinjatovo, Daniel Stiehl, Eva Deininger, Markus Rechsteiner, Holger Moch,  and Peter Schraml
10199-10212
Abstract  |  PDF  |  HTML  |  Order a Reprint

EZH2 inhibition in multiple myeloma downregulates myeloma associated oncogenes and upregulates microRNAs with potential tumor suppressor functions

EZH2 inhibition in multiple myeloma downregulates myeloma associated oncogenes and upregulates microRNAs with potential tumor suppressor functions

https://doi.org/10.18632/oncotarget.14378

Mohammad Alzrigat, Alba Atienza Párraga, Prasoon Agarwal, Hadil Zureigat, Anders Österborg, Hareth Nahi, Anqi Ma, Jian Jin, Kenneth Nilsson, Fredrik Öberg, Antonia Kalushkova,  and Helena Jernberg-Wiklund
10213-10224
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic disruption of the pHi-regulating proteins Na+/H+ exchanger 1 (SLC9A1) and carbonic anhydrase 9 severely reduces growth of colon cancer cells

Genetic disruption of the pHi-regulating proteins Na+/H+ exchanger 1 (SLC9A1) and carbonic anhydrase 9 severely reduces growth of colon cancer cells

https://doi.org/10.18632/oncotarget.14379

Scott K. Parks, Yann Cormerais, Jerome Durivault,  and Jacques Pouyssegur
10225-10237
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The biological properties of different Epstein-Barr virus strains explain their association with various types of cancers

The biological properties of different Epstein-Barr virus strains explain their association with various types of cancers

https://doi.org/10.18632/oncotarget.14380

Ming-Han Tsai, Xiaochen Lin, Anatoliy Shumilov, Katharina Bernhardt, Regina Feederle, Remy Poirey, Annette Kopp-Schneider, Bruno Pereira, Raquel Almeida,  and Henri-Jacques Delecluse
10238-10254
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Association of genetic polymorphisms with laryngeal carcinoma prognosis in a Chinese population

Association of genetic polymorphisms with laryngeal carcinoma prognosis in a Chinese population

https://doi.org/10.18632/oncotarget.14381

Fang Quan, Feipeng Zhang, Yanxia Bai, Long Zhou, Hua Yang, Bin Li, Tianbo Jin, Huajing Li,  and Yuan Shao
10255-10263
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MET overexpression, gene amplification and relevant clinicopathological features in gastric adenocarcinoma

MET overexpression, gene amplification and relevant clinicopathological features in gastric adenocarcinoma

https://doi.org/10.18632/oncotarget.14382

Jing Zhang, Lei Guo, Xiuyun Liu, Wenbin Li,  and Jianming Ying
10264-10273
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miR-124 represses the mesenchymal features and suppresses metastasis in Ewing sarcoma

miR-124 represses the mesenchymal features and suppresses metastasis in Ewing sarcoma

https://doi.org/10.18632/oncotarget.14394

Yunyun Li, Gaohai Shao, Minghua Zhang, Fengchen Zhu, Bo Zhao, Chao He,  and Zhongzu Zhang
10274-10286
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Dual inhibition of PCDH9 expression by miR-215-5p up-regulation in gliomas

Dual inhibition of PCDH9 expression by miR-215-5p up-regulation in gliomas

https://doi.org/10.18632/oncotarget.14396

Chunlin Wang, Qi Chen, Shu Li, Shiting Li, Zhenyu Zhao, Hongliang Gao, Xiaoqiang Wang, Bin Li, Wenchuan Zhang, Yan Yuan, Linzhao Ming, Hua He, Bangbao Tao,  and Jun Zhong
10287-10297
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Cycling hypoxia affects cell invasion and proliferation through direct regulation of claudin1 / claudin7 expression, and indirect regulation of P18 through claudin7

Cycling hypoxia affects cell invasion and proliferation through direct regulation of claudin1 / claudin7 expression, and indirect regulation of P18 through claudin7

https://doi.org/10.18632/oncotarget.14397

Hong Liu, Feifei Jiang, Xinshan Jia, Jing Lan, Hao Guo, Erran Li, Aihui Yan,  and Yan Wang
10298-10311
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Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM

Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM

https://doi.org/10.18632/oncotarget.14400

Jennifer Ma, Jeremy Setton, Luc Morris, Pedro Blecua Carrillo Albornoz, Christopher Barker, Benjamin H. Lok, Eric Sherman, Nora Katabi, Kathryn Beal, Ian Ganly, Simon N. Powell, Nancy Lee, Timothy A. Chan,  and Nadeem Riaz
10312-10323
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Src promotes castration-recurrent prostate cancer through androgen receptor-dependent canonical and non-canonical transcriptional signatures

Src promotes castration-recurrent prostate cancer through androgen receptor-dependent canonical and non-canonical transcriptional signatures

https://doi.org/10.18632/oncotarget.14401

Indranil Chattopadhyay, Jianmin Wang, Maochun Qin, Lingqiu Gao, Renae Holtz, Robert L. Vessella, Robert W. Leach,  and Irwin H. Gelman
10324-10347
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Expression of Notch1 and Numb in small cell lung cancer

Expression of Notch1 and Numb in small cell lung cancer

https://doi.org/10.18632/oncotarget.14411

Hajime Kikuchi, Jun Sakakibara-Konishi, Megumi Furuta, Hiroshi Yokouchi, Hiroshi Nishihara, Shigeo Yamazaki, Hidetaka Uramoto, Fumihiro Tanaka, Masao Harada, Kenji Akie, Fumiko Sugaya, Yuka Fujita, Kei Takamura, Tetsuya Kojima, Toshiyuki Harada, Mitsunori Higuchi, Osamu Honjo, Yoshinori Minami, Naomi Watanabe, Satoshi Oizumi, Hiroyuki Suzuki, Takashi Ishida, Hirotoshi Dosaka-Akita, Hiroshi Isobe, Mitsuru Munakata,  and Masaharu Nishimura
10348-10358
Abstract  |  PDF  |  HTML  |  Order a Reprint

Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels

Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels

https://doi.org/10.18632/oncotarget.14413

Guo-Bing Li, Ruo-Qiu Fu, Han-Ming Shen, Jing Zhou, Xiao-Ye Hu, Yan-Xia Liu, Yu-Nong Li, Hong-Wei Zhang, Xin Liu, Yan-Hao Zhang, Cheng Huang, Rong Zhang,  and Ning Gao
10359-10374
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Is the pathological regression level of metastatic lymph nodes associated with oncologic outcomes following preoperative chemoradiotherapy in rectal cancer?

Is the pathological regression level of metastatic lymph nodes associated with oncologic outcomes following preoperative chemoradiotherapy in rectal cancer?

https://doi.org/10.18632/oncotarget.14418

Jung Pil Choi, Seong Joo Kim, In Ja Park, Seung Mo Hong, Jong Lyul Lee, Yong Sik Yoon, Chan Wook Kim, Seok-Byung Lim, Jung Bok Lee, Chang Sik Yu,  and Jin Cheon Kim
10375-10384
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

NIDO, AMOP and vWD domains of MUC4 play synergic role in MUC4 mediated signaling

NIDO, AMOP and vWD domains of MUC4 play synergic role in MUC4 mediated signaling

https://doi.org/10.18632/oncotarget.14420

Yi Zhu, Jing-Jing Zhang, Yun-Peng Peng, Xian Liu, Kun-Ling Xie, Jie Tang, Kui-Rong Jiang, Wen-Tao Gao, Lei Tian, Kai Zhang, Ze-Kuan Xu,  and Yi Miao
10385-10399
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The small heat shock protein B8 (HSPB8) modulates proliferation and migration of breast cancer cells

The small heat shock protein B8 (HSPB8) modulates proliferation and migration of breast cancer cells

https://doi.org/10.18632/oncotarget.14422

Margherita Piccolella, Valeria Crippa, Riccardo Cristofani, Paola Rusmini, Mariarita Galbiati, Maria Elena Cicardi, Marco Meroni, Nicola Ferri, Federica F. Morelli, Serena Carra, Elio Messi,  and Angelo Poletti
10400-10415
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevated spondin-2 expression correlates with progression and prognosis in gastric cancer

Elevated spondin-2 expression correlates with progression and prognosis in gastric cancer

https://doi.org/10.18632/oncotarget.14423

Chuan Jin, Jin-Rong Lin, Lei Ma, Ye Song, Yan-Xia Shi, Peng Jiang, Ye Dong,  and Xiao-Shan Li
10416-10424
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Immunogenic cancer cell death selectively induced by near infrared photoimmunotherapy initiates host tumor immunity

Immunogenic cancer cell death selectively induced by near infrared photoimmunotherapy initiates host tumor immunity

https://doi.org/10.18632/oncotarget.14425

Mikako Ogawa, Yusuke Tomita, Yuko Nakamura, Min-Jung Lee, Sunmin Lee, Saori Tomita, Tadanobu Nagaya, Kazuhide Sato, Toyohiko Yamauchi, Hidenao Iwai, Abhishek Kumar, Timothy Haystead, Hari Shroff, Peter L. Choyke, Jane B. Trepel,  and Hisataka Kobayashi
10425-10436
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Blockade of the malignant phenotype by β-subunit selective noncovalent inhibition of immuno- and constitutive proteasomes

Blockade of the malignant phenotype by β-subunit selective noncovalent inhibition of immuno- and constitutive proteasomes

https://doi.org/10.18632/oncotarget.14428

Bruno O. Villoutreix, Abdel-Majid Khatib, Yan Cheng, Maria A. Miteva, Xavier Maréchal, Joëlle Vidal,  and Michèle Reboud-Ravaux
10437-10449
Abstract  |  PDF  |  HTML  |  Order a Reprint

Associations between genetic variants in immunoregulatory genes and risk of non-Hodgkin lymphoma in a Chinese population

Associations between genetic variants in immunoregulatory genes and risk of non-Hodgkin lymphoma in a Chinese population

https://doi.org/10.18632/oncotarget.14426

Xibiao Ye, Kaiqiong Zhao, Cuie Wu, Pingzhao Hu,  and Hua Fu
10450-10457
Abstract  |  PDF  |  HTML  |  Order a Reprint

Folate intake, serum folate levels and esophageal cancer risk: an overall and dose-response meta-analysis

Folate intake, serum folate levels and esophageal cancer risk: an overall and dose-response meta-analysis

https://doi.org/10.18632/oncotarget.14432

Yan Zhao, Chenyang Guo, Hongtao Hu, Lin Zheng, Junli Ma, Li Jiang, Erjiang Zhao,  and Hailiang Li
10458-10469
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Baicalein has protective effects on the 17β-estradiol-induced transformation of breast epithelial cells

Baicalein has protective effects on the 17β-estradiol-induced transformation of breast epithelial cells

https://doi.org/10.18632/oncotarget.14433

Yan Chen, Jing Wang, Duan-Yang Hong, Lin Chen, Yan-Yan Zhang, Yi-Ni Xu, Di Pan, Ling-Yun Fu, Ling Tao, Hong Luo,  and Xiang-Chun Shen
10470-10484
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A potential prognostic lncRNA signature for predicting survival in patients with bladder urothelial carcinoma

A potential prognostic lncRNA signature for predicting survival in patients with bladder urothelial carcinoma

https://doi.org/10.18632/oncotarget.14441

Zhenyu Bao, Weitao Zhang,  and Dong Dong
10485-10497
Abstract  |  PDF  |  HTML  |  Order a Reprint

Investigating the utility of human melanoma cell lines as tumour models

Investigating the utility of human melanoma cell lines as tumour models

https://doi.org/10.18632/oncotarget.14443

Krista Marie Vincent,  and Lynne-Marie Postovit
10498-10509
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevated UHRF1 expression contributes to poor prognosis by promoting cell proliferation and metastasis in hepatocellular carcinoma

Elevated UHRF1 expression contributes to poor prognosis by promoting cell proliferation and metastasis in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.14446

Xincheng Liu, Huohui Ou, Leyang Xiang, Xianghong Li, Yu Huang,  and Dinghua Yang
10510-10522
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Genetic polymorphisms in TERT are associated with increased risk of esophageal cancer

Genetic polymorphisms in TERT are associated with increased risk of esophageal cancer

https://doi.org/10.18632/oncotarget.14451

Yifei Wu, Mengdan Yan, Jing Li, Jingjie Li, Zhengshuai Chen, Peng Chen, Bin Li, Fulin Chen, Tianbo Jin,  and Chao Chen
10523-10530
Abstract  |  PDF  |  HTML  |  Order a Reprint

Opposing roles of PIK3CA gene alterations to EZH2 signaling in non-muscle invasive bladder cancer

Opposing roles of PIK3CA gene alterations to EZH2 signaling in non-muscle invasive bladder cancer

https://doi.org/10.18632/oncotarget.14453

Cristina Segovia, Mónica Martínez-Fernández, Marta Dueñas, Carolina Rubio, Fernando F. López-Calderón, Clotilde Costa, Cristina Saiz-Ladera, María Fernández-Grajera, José Duarte, Huberto García Muñoz, Federico de la Rosa, Felipe Villacampa, Daniel Castellano,  and Jesús M. Paramio
10531-10542
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeted activation of AMPK by GSK621 ameliorates H2O2-induced damages in osteoblasts

Targeted activation of AMPK by GSK621 ameliorates H2O2-induced damages in osteoblasts

https://doi.org/10.18632/oncotarget.14454

Weidong Liu, Li Mao, Feng Ji, Fengli Chen, Yuedong Hao,  and Gang Liu
10543-10552
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cytotoxic T-lymphocyte-associated protein 4 +49A/G polymorphisms contribute to the risk of type 1 diabetes in children: An updated systematic review and meta-analysis with trial sequential analysis

Cytotoxic T-lymphocyte-associated protein 4 +49A/G polymorphisms contribute to the risk of type 1 diabetes in children: An updated systematic review and meta-analysis with trial sequential analysis

https://doi.org/10.18632/oncotarget.14457

Bo Wang, Wei Du, Yutao Jia, Xiaobai Zhang,  and Guorui Ma
10553-10564
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A short-term intervention with selenium affects expression of genes implicated in the epithelial-to-mesenchymal transition in the prostate

A short-term intervention with selenium affects expression of genes implicated in the epithelial-to-mesenchymal transition in the prostate

https://doi.org/10.18632/oncotarget.14551

Dieuwertje E.G. Kok, Lambertus A.L.M. Kiemeney, Gerald W. Verhaegh, Jack A. Schalken, Emile N.J.T. van Lin, J.P. Michiel Sedelaar, J. Alfred Witjes, Christina A. Hulsbergen - van de Kaa, Pieter van ’t Veer, Ellen Kampman,  and Lydia A. Afman
10565-10579
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype

Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype

https://doi.org/10.18632/oncotarget.14554

Branden M. Hopkinson, Marie C. Klitgaard, Ole William Petersen, René Villadsen, Lone Rønnov-Jessen,  and Jiyoung Kim
10580-10593
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Clinical Research Papers

Implication of comorbidity on the initiation of chemotherapy and survival outcomes in patients with locoregionally advanced nasopharyngeal carcinoma

Implication of comorbidity on the initiation of chemotherapy and survival outcomes in patients with locoregionally advanced nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.8621

Rui Guo, Yan-Ping Mao, Lei chen, Ling-Long Tang, Guan-Qun Zhou, Li-Zhi Liu, Li Tian, Mu-Sheng Zeng, Wei-Hua Jia, Jian-Yong Shao, Ai-Hua Lin,  and Jun Ma
10594-10601
Abstract  |  PDF  |  HTML  |  Order a Reprint

Fertility-sparing surgery for patients with low-grade endometrial stromal sarcoma

Fertility-sparing surgery for patients with low-grade endometrial stromal sarcoma

https://doi.org/10.18632/oncotarget.12491

Weimin Xie, Dongyan Cao, Jiaxin Yang, Xuan Jiang, Keng Shen, Lingya Pan, Huifang Huang, Jinghe Lang, Yan You,  and Jie Chen
10602-10608
Abstract  |  PDF  |  HTML  |  Order a Reprint

The microbial community shifts of subgingival plaque in patients with generalized aggressive periodontitis following non-surgical periodontal therapy: a pilot study

The microbial community shifts of subgingival plaque in patients with generalized aggressive periodontitis following non-surgical periodontal therapy: a pilot study

https://doi.org/10.18632/oncotarget.12532

Jing Han, Peng Wang,  and Shaohua Ge
10609-10619
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Quantitative assessment of background parenchymal enhancement in breast magnetic resonance images predicts the risk of breast cancer

Quantitative assessment of background parenchymal enhancement in breast magnetic resonance images predicts the risk of breast cancer

https://doi.org/10.18632/oncotarget.13538

Xiaoxin Hu, Luan Jiang, Qiang Li,  and Yajia Gu
10620-10627
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Effects of continuous renal replacement therapy on serum cytokines, neutrophil gelatinase-associated lipocalin, and prognosis in patients with severe acute kidney injury after cardiac surgery

Effects of continuous renal replacement therapy on serum cytokines, neutrophil gelatinase-associated lipocalin, and prognosis in patients with severe acute kidney injury after cardiac surgery

https://doi.org/10.18632/oncotarget.13254

Heng-jin Wang, Pei Wang, Nan Li, Cheng Wan, Chun-ming Jiang, Jing-song He, Dong-jin Wang, Miao Zhang,  and Ling-yun Sun
10628-10636
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

The changing characteristics and molecular profiles of papillary thyroid carcinoma over time: a systematic review

The changing characteristics and molecular profiles of papillary thyroid carcinoma over time: a systematic review

https://doi.org/10.18632/oncotarget.12885

Huy Gia Vuong, Ahmed M.A. Altibi, Amr Hesham Abdelhamid, Phuong Uyen Duong Ngoc, Vo Duy Quan, Mohamed Yousef Tantawi, Mohamed Elfil, Tran Le Huy Vu, Ahmed Elgebaly, Naoki Oishi, Tadao Nakazawa, Kenji Hirayama, Ryohei Katoh, Nguyen Tien Huy,  and Tetsuo Kondo
10637-10649
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Macrophage migration inhibitory factor: a potential driver and biomarker for head and neck squamous cell carcinoma

Macrophage migration inhibitory factor: a potential driver and biomarker for head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.12890

Sha-sha Wang, Xiao Cen, Xin-hua Liang,  and Ya-ling Tang
10650-10661
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FoxO1: a novel insight into its molecular mechanisms in the regulation of skeletal muscle differentiation and fiber type specification

FoxO1: a novel insight into its molecular mechanisms in the regulation of skeletal muscle differentiation and fiber type specification

https://doi.org/10.18632/oncotarget.12891

Meng Xu, Xiaoling Chen, Daiwen Chen, Bing Yu,  and Zhiqing Huang
10662-10674
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Mammary gland stem cells and their application in breast cancer

Mammary gland stem cells and their application in breast cancer

https://doi.org/10.18632/oncotarget.12893

Xing Yang, Hui Wang,  and Baowei Jiao
10675-10691
Abstract  |  PDF  |  HTML  |  Order a Reprint

A systematic review and meta-analysis: Does hepatitis C virus infection predispose to the development of chronic kidney disease?

A systematic review and meta-analysis: Does hepatitis C virus infection predispose to the development of chronic kidney disease?

https://doi.org/10.18632/oncotarget.12896

Min Li, Peiyuan Wang, Chunhua Yang, Wenguo Jiang, Xiaodan Wei, Xinbo Mu, Xuri Li, Jia Mi,  and Geng Tian
10692-10702
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Bevacizumab combined with chemotherapy for ovarian cancer: an updated systematic review and meta-analysis of randomized controlled trials

Bevacizumab combined with chemotherapy for ovarian cancer: an updated systematic review and meta-analysis of randomized controlled trials

https://doi.org/10.18632/oncotarget.12926

Yu Shen Wu, Lin Shui, Dan Shen,  and Xiaopin Chen
10703-10713
Abstract  |  PDF  |  HTML  |  Order a Reprint

FDA-approved medications that impair human spermatogenesis

FDA-approved medications that impair human spermatogenesis

https://doi.org/10.18632/oncotarget.12956

Jiayi Ding, Xuejun Shang, Zhanhu Zhang, Hua Jing, Jun Shao, Qianqian Fei, Haibo Li,  and Elizabeth R. Rayburn
10714-10725
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Long noncoding RNAs in head and neck cancer

Long noncoding RNAs in head and neck cancer

https://doi.org/10.18632/oncotarget.12960

Xiuhua Li, Yongbing Cao, Xiaojian Gong,  and Hongjiao Li
10726-10740
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical outcomes of laparoscopic-assisted synchronous bowel anastomoses for synchronous colorectal cancer: initial clinical experience

Clinical outcomes of laparoscopic-assisted synchronous bowel anastomoses for synchronous colorectal cancer: initial clinical experience

https://doi.org/10.18632/oncotarget.12899

Zhengtian Li, Dawei Wang, Yunwei Wei, Peng Liu,  and Jun Xu
10741-10747
Abstract  |  PDF  |  HTML  |  Order a Reprint

Magic year for multiple myeloma therapeutics: Key takeaways from the ASH 2015 annual meeting

Magic year for multiple myeloma therapeutics: Key takeaways from the ASH 2015 annual meeting

https://doi.org/10.18632/oncotarget.13314

Kejie Zhang, Aakash Desai, Dongfeng Zeng, Tiejun Gong, Peihua Lu,  and Michael Wang
10748-10759
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Corrections

Correction: Lapatinib inhibits CIP2A/PP2A/p-Akt signaling and induces apoptosis in triple negative breast cancer cells

Correction: Lapatinib inhibits CIP2A/PP2A/p-Akt signaling and induces apoptosis in triple negative breast cancer cells

https://doi.org/10.18632/oncotarget.15112

Chun-Yu Liu, Ming-Hung Hu, Chia-Jung Hsu, Chun-Teng Huang, Duen-Shian Wang, Wen-Chun Tsai, Yi-Ting Chen, Chia-Han Lee, Pei-Yi Chu, Chia-Chi Hsu, Ming-Huang Chen, Chung-Wai Shiau, Ling-Ming Tseng,  and Kuen-Feng Chen
10760-10760
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