About The Cover
C57BL6 mice bearing orthotopic brain tumors were treated with a therapeutic agents 12 days after tumor implantation. In this particular animal, two tumor nodules developed along the injection track and both showed tumor accumulation of 125I-labeled SSLs when TNF-α was co-administered. See Qiao et al.
Table of Contents
Commentaries
| A conspiracy of glioma and endothelial cells to invade the normal brain. |
| Abdessamad Zerrouqi, and Erwin G Van Meir |
| 1-4 |
| PDF HTML |
| Targeting Transcription Through Inhibition of TBP |
| Thaddeus T. Schug |
| 5-7 |
| PDF HTML |
Reviews
| The Emerging Role of the Thrombin Receptor (PAR-1) in Melanoma Metastasis - a Possible Therapeutic Target |
| Gabriel J. Villares, Maya Zigler, and Menashe Bar-Eli |
| 8-17 |
| Abstract PDF HTML |
Research Papers
| Identification of Kinase Inhibitors that Target Transcription Initiation by RNA Polymerase II |
| José M. Morachis, Ruo Huang, and Beverly M. Emerson |
| 18-28 |
| Abstract PDF HTML Supplementary Files |
| miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma |
| Nijiro Nohata, Yaeko Sone, Toyoyuki Hanazawa, Miki Fuse, Naoko Kikkawa, Hirofumi Yoshino, Takeshi Chiyomaru, Kazumori Kawakami, Hideki Enokida, Masayuki Nakagawa, Makio Shozu, Yoshitaka Okamoto, and Naohiko Seki |
| 29-42 |
| Abstract PDF HTML |
| Hsp90 can Accommodate the Simultaneous Binding of the FKBP52 and HOP Proteins |
| Zacariah L. Hildenbrand, Sudheer K. Molugu, Nadia Herrera, Citlally Ramirez, Chuan Xiao, and Ricardo A. Bernal |
| 43-58 |
| Abstract PDF HTML Supplementary Files |
| A Robust Approach to Enhance Tumor-selective Accumulation of Nanoparticles |
| Yuan Qiao, Xin Huang, Sridhar Nimmagadda, Renyuan Bai, Verena Staedtke, Catherine A. Foss, Ian Cheong, Matthias Holdhoff, Yoshinori Kato, Martin G. Pomper, Gregory J. Riggins, Kenneth W. Kinzler, Luis A. Diaz, Bert Vogelstein, and Shibin Zhou |
| 59-68 |
| Abstract PDF HTML Supplementary Files |
| FAM190A Rearrangements Provide a Multitude of Individualized Tumor Signatures and Neo-antigens in Cancer |
| Francesca Scrimieri, Eric S. Calhoun, Kalpesh Patel, Rigu Gupta, David L. Huso, Ralph H. Hruban, and Scott E. Kern |
| 69-75 |
| Abstract PDF HTML Supplementary Files |
Research Perspectives
| Targeting Translation Dependence in Cancer |
| Abba Malina, Regina Cencic, and Jerry Pelletier |
| 76-88 |
| Abstract PDF HTML |
| Insights into 4E-BP1 and p53 mediated regulation of accelerated cell senescence |
| Suzan K Chao, Susan Band Horwitz, and Hayley M. McDaid |
| 89-98 |
| Abstract PDF HTML |
| Eradicating cancer cells: struggle with a chameleon |
| Jiabo Di, Tjitske Duiveman-de Boer, Carl G Figdor, and Ruurd Torensma |
| 99-101 |
| Abstract PDF HTML |
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