Oncotarget

Vol 8, No 3

January 17, 2017

View Archive »

Order a Reprint

About The Cover

The cover for issue 3 of Oncotarget features Figure 2C,  'Intermediate chemotherapy dosing fully normalizes body weight of non tumor-bearing obese mice,' from Myers, et al.

Table of Contents

Editorial

Redox unbalance modifies neurogenic potential

Redox unbalance modifies neurogenic potential

https://doi.org/10.18632/oncotarget.14110

Marilena Raciti,  and Sandra Ceccatelli
3762-3763
PDF  |  Order a Reprint

Directly converted iNeuron as a screening model for pathogenic variants

Directly converted iNeuron as a screening model for pathogenic variants

https://doi.org/10.18632/oncotarget.14111

Su Min Lim, Chang-Seok Ki,  and Seung Hyun Kim
3764-3765
PDF  |  Order a Reprint

Editorial: Neuroscience

Naringenin: an analgesic and anti-inflammatory citrus flavanone

Naringenin: an analgesic and anti-inflammatory citrus flavanone

https://doi.org/10.18632/oncotarget.14084

Marília F. Manchope, Rubia Casagrande,  and Waldiceu A. Verri, Jr.
3766-3767
PDF  |  Order a Reprint

mGluR5, CB1 and neuroprotection

mGluR5, CB1 and neuroprotection

https://doi.org/10.18632/oncotarget.14086

Toniana G. Carvalho, Juliana G. Doria,  and Fabiola M. Ribeiro
3768-3769
PDF  |  Order a Reprint

Cerebrospinal fluid in Alzheimer’s: A precious tool

Cerebrospinal fluid in Alzheimer’s: A precious tool

https://doi.org/10.18632/oncotarget.14157

Lucilla Parnetti,  and Claudia Cicognola
3770-3770
PDF  |  Order a Reprint

Exploring ncRNAs in Alzheimer’s disease by miRMaster

Exploring ncRNAs in Alzheimer’s disease by miRMaster

https://doi.org/10.18632/oncotarget.14054

Tobias Fehlmann, Eckart Meese,  and Andreas Keller
3771-3772
PDF  |  Order a Reprint

Research Papers: Pathology

Melatonin protects against arsenic trioxide-induced liver injury by the upregulation of Nrf2 expression through the activation of PI3K/AKT pathway

Melatonin protects against arsenic trioxide-induced liver injury by the upregulation of Nrf2 expression through the activation of PI3K/AKT pathway

https://doi.org/10.18632/oncotarget.13931

Yue Zhang, Zhengkai Wei, Weijian Liu, Jingjing Wang, Xuexiu He, Hailong Huang, Jiali Zhang,  and Zhengtao Yang
3773-3780
Abstract  |  PDF  |  HTML  |  Order a Reprint

Epoxyeicosanoids prevent intervertebral disc degeneration in vitro and in vivo

Epoxyeicosanoids prevent intervertebral disc degeneration in vitro and in vivo

https://doi.org/10.18632/oncotarget.14389

Jing Li, Hanfeng Guan, Huiyong Liu, Libo Zhao, Li Li, Yong Zhang, Peng Tan, Baoguo Mi,  and Feng Li
3781-3797
Abstract  |  PDF  |  HTML  |  Order a Reprint

Research Papers: Immunology

Dysbiosis of urinary microbiota is positively correlated with Type 2 diabetes mellitus

Dysbiosis of urinary microbiota is positively correlated with Type 2 diabetes mellitus

https://doi.org/10.18632/oncotarget.14028

Fengping Liu, Zongxin Ling, Yonghong Xiao, Longxian Lv, Qing Yang, Baohong Wang, Haifeng Lu, Li Zheng, Ping Jiang, Wei Wang,  and Lanjuan Li
3798-3810
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers

Aberrant regulation of RANKL/OPG in women at high risk of developing breast cancer

Aberrant regulation of RANKL/OPG in women at high risk of developing breast cancer

https://doi.org/10.18632/oncotarget.14013

Stefan Kiechl, Daniel Schramek, Martin Widschwendter, Evangelia-Ourania Fourkala, Alexey Zaikin, Allison Jones, Bernadette Jaeger, Brigitte Rack, Wolfgang Janni, Christoph Scholz, Johann Willeit, Siegfried Weger, Agnes Mayr, Andrew Teschendorff, Adam Rosenthal, Lindsay Fraser, Susan Philpott, Louis Dubeau, Mohammed Keshtgar, Rebecca Roylance, Ian J. Jacobs, Usha Menon, Georg Schett,  and Josef M. Penninger
3811-3825
Abstract  |  PDF  |  HTML  |  Order a Reprint

Loss of TGFβ signaling promotes colon cancer progression and tumor-associated inflammation

Loss of TGFβ signaling promotes colon cancer progression and tumor-associated inflammation

https://doi.org/10.18632/oncotarget.9830

Daniel R. Principe, Brian DeCant, Jonas Staudacher, Dominic Vitello, Riley J. Mangan, Elizabeth A. Wayne, Emman Mascariñas, Andrew M. Diaz, Jessica Bauer, Ronald D. McKinney, Khashayarsha Khazaie, Boris Pasche, David W. Dawson, Hidayatullah G. Munshi, Paul J. Grippo,  and Barbara Jung
3826-3839
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Signaling regulation and role of filamin A cleavage in Ca2+-stimulated migration of androgen receptor-deficient prostate cancer cells

Signaling regulation and role of filamin A cleavage in Ca2+-stimulated migration of androgen receptor-deficient prostate cancer cells

https://doi.org/10.18632/oncotarget.9472

Chunfa Huang, R. Tyler Miller,  and Carl E. Freter
3840-3853
Abstract  |  PDF  |  HTML  |  Order a Reprint

LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene

LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene

https://doi.org/10.18632/oncotarget.12924

Susanna Ambrosio, Stefano Amente, Carmen D. Saccà, Mario Capasso, Raffaele A. Calogero, Luigi Lania,  and Barbara Majello
3854-3869
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Quantitative assessment of Zirconium-89 labeled cetuximab using PET/CT imaging in patients with advanced head and neck cancer: a theragnostic approach

Quantitative assessment of Zirconium-89 labeled cetuximab using PET/CT imaging in patients with advanced head and neck cancer: a theragnostic approach

https://doi.org/10.18632/oncotarget.13910

Aniek J.G. Even, Olga Hamming-Vrieze, Wouter van Elmpt, Véronique J.L. Winnepenninckx, Jolien Heukelom, Margot E.T. Tesselaar, Wouter V. Vogel, Ann Hoeben, Catharina M.L. Zegers, Daniëlle J. Vugts, Guus A.M.S. van Dongen, Harry Bartelink, Felix M. Mottaghy, Frank Hoebers,  and Philippe Lambin
3870-3880
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Endometrial cancer cells exhibit high expression of p110β and its selective inhibition induces variable responses on PI3K signaling, cell survival and proliferation

Endometrial cancer cells exhibit high expression of p110β and its selective inhibition induces variable responses on PI3K signaling, cell survival and proliferation

https://doi.org/10.18632/oncotarget.13989

Thomas Karlsson, Camilla Krakstad, Ingvild Løberg Tangen, Erling A. Hoivik, Pamela M. Pollock, Helga B. Salvesen,  and Aurélia E. Lewis
3881-3894
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oxidative stress, a trigger of hepatitis C and B virus-induced liver carcinogenesis

Oxidative stress, a trigger of hepatitis C and B virus-induced liver carcinogenesis

https://doi.org/10.18632/oncotarget.13904

Alexander V. Ivanov, Vladimir T. Valuev-Elliston, Daria A. Tyurina, Olga N. Ivanova, Sergey N. Kochetkov, Birke Bartosch,  and Maria G. Isaguliants
3895-3932
Abstract  |  PDF  |  HTML  |  Order a Reprint

The role of tumor microenvironment in therapeutic resistance

The role of tumor microenvironment in therapeutic resistance

https://doi.org/10.18632/oncotarget.13907

Beomseok Son, Sungmin Lee, HyeSook Youn, EunGi Kim, Wanyeon Kim,  and BuHyun Youn
3933-3945
Abstract  |  PDF  |  HTML  |  Order a Reprint

Management of salivary gland carcinomas - a review

Management of salivary gland carcinomas - a review

https://doi.org/10.18632/oncotarget.13952

Xiaoli Wang, Yijun Luo, Minghuan Li, Hongjiang Yan, Mingping Sun,  and Tingyong Fan
3946-3956
Abstract  |  PDF  |  HTML  |  Order a Reprint

The prognostic significance of long noncoding RNAs in non-small cell lung cancer: a meta-analysis

The prognostic significance of long noncoding RNAs in non-small cell lung cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.13956

Wei Jing, Nandi Li, Yingchao Wang, Xuefang Liu, Shengjun Liao, Hongyan Chai,  and Jiancheng Tu
3957-3968
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sex chromosome abnormalities and psychiatric diseases

Sex chromosome abnormalities and psychiatric diseases

https://doi.org/10.18632/oncotarget.13962

Xinzhu zhang, Jian Yang, Yuhong Li, Xin Ma,  and Rena Li
3969-3979
Abstract  |  PDF  |  HTML  |  Order a Reprint

Mechanisms of resistance to anti-EGFR therapy in colorectal cancer

Mechanisms of resistance to anti-EGFR therapy in colorectal cancer

https://doi.org/10.18632/oncotarget.14012

Ben Zhao, Lu Wang, Hong Qiu, Mingsheng Zhang, Li Sun, Ping Peng, Qianqian Yu,  and Xianglin Yuan
3980-4000
Abstract  |  PDF  |  HTML  |  Order a Reprint

MiR-142 inhibits the development of cervical cancer by targeting HMGB1

MiR-142 inhibits the development of cervical cancer by targeting HMGB1

https://doi.org/10.18632/oncotarget.13136

Daqiong Jiang, Huiyan Wang, Zhuyan Li, Zhen Li, Xin Chen,  and Hongbing Cai
4001-4007
Abstract  |  PDF  |  HTML  |  Order a Reprint

Chemoresistance and targeted therapies in ovarian and endometrial cancers

Chemoresistance and targeted therapies in ovarian and endometrial cancers

https://doi.org/10.18632/oncotarget.14021

Kevin Brasseur, Nicolas Gévry,  and Eric Asselin
4008-4042
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Systematic review of CYFRA 21-1 as a prognostic indicator and its predictive correlation with clinicopathological features in Non-small Cell Lung Cancer: A meta-analysis

Systematic review of CYFRA 21-1 as a prognostic indicator and its predictive correlation with clinicopathological features in Non-small Cell Lung Cancer: A meta-analysis

https://doi.org/10.18632/oncotarget.14022

Zipu Yu, Guofei Zhang, Maoying Yang, Sai Zhang, Baiqin Zhao, Gang Shen,  and Ying Chai
4043-4050
Abstract  |  PDF  |  HTML  |  Order a Reprint

Isochaihulactone-induced DDIT3 causes ER stress-PERK independent apoptosis in glioblastoma multiforme cells

Isochaihulactone-induced DDIT3 causes ER stress-PERK independent apoptosis in glioblastoma multiforme cells

https://doi.org/10.18632/oncotarget.13266

Sheng-Feng Tsai, Michael Tao, Li-Ing Ho, Tzyy-Wen Chiou, Shinn-Zong Lin, Hong-Lin Su,  and Horng-Jyh Harn
4051-4061
Abstract  |  PDF  |  HTML  |  Order a Reprint

The JAZF1-SUZ12 Fusion Protein Disrupts PRC2 Complexes and Impairs Chromatin Repression During Human Endometrial Stromal Tumorogenesis

The JAZF1-SUZ12 Fusion Protein Disrupts PRC2 Complexes and Impairs Chromatin Repression During Human Endometrial Stromal Tumorogenesis

https://doi.org/10.18632/oncotarget.13270

Xianyong Ma, Jinglan Wang, Jianhui Wang, Charles X. Ma, Xiaobin Gao, Vytas Patriub,  and Jeffrey L. Sklar
4062-4078
Abstract  |  PDF  |  HTML  |  Order a Reprint

In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma

In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma

https://doi.org/10.18632/oncotarget.13385

Ziyan Y. Pessetto, Bin Chen, Hani Alturkmani, Stephen Hyter, Colleen A. Flynn, Michael Baltezor, Yan Ma, Howard G. Rosenthal, Kathleen A. Neville, Scott J. Weir, Atul J. Butte,  and Andrew K. Godwin
4079-4095
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

YAP1 regulates ABCG2 and cancer cell side population in human lung cancer cells

YAP1 regulates ABCG2 and cancer cell side population in human lung cancer cells

https://doi.org/10.18632/oncotarget.13686

Yuyuan Dai, Shu Liu, Wen-Qian Zhang, Yi-Lin Yang, Phillip Hang, Hui Wang, Li Cheng, Ping-Chih Hsu, Yu-Chen Wang, Zhidong Xu, David M. Jablons,  and Liang You
4096-4109
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

An annotated list of bivalent chromatin regions in human ES cells: a new tool for cancer epigenetic research

An annotated list of bivalent chromatin regions in human ES cells: a new tool for cancer epigenetic research

https://doi.org/10.18632/oncotarget.13746

Franck Court,  and Philippe Arnaud
4110-4124
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long non-coding RNA XIST promotes cell growth and invasion through regulating miR-497/MACC1 axis in gastric cancer

Long non-coding RNA XIST promotes cell growth and invasion through regulating miR-497/MACC1 axis in gastric cancer

https://doi.org/10.18632/oncotarget.13670

Lei Ma, Yongjian Zhou, Xiaojun Luo, Hai Gao, Xubin Deng,  and Yingjie Jiang
4125-4135
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Altered microRNA profiles in plasma exosomes from mesial temporal lobe epilepsy with hippocampal sclerosis

Altered microRNA profiles in plasma exosomes from mesial temporal lobe epilepsy with hippocampal sclerosis

https://doi.org/10.18632/oncotarget.13744

Shaofeng Yan, Hua Zhang, Wenyan Xie, Fangang Meng, Kai Zhang, Yin Jiang, Xin Zhang,  and Jianguo Zhang
4136-4146
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Antitumor effect of combination of the inhibitors of two new oncotargets: proton pumps and reverse transcriptase

Antitumor effect of combination of the inhibitors of two new oncotargets: proton pumps and reverse transcriptase

https://doi.org/10.18632/oncotarget.13792

Luana Lugini, Ilaria Sciamanna, Cristina Federici, Elisabetta Iessi, Enrico Pierluigi Spugnini,  and Stefano Fais
4147-4155
Abstract  |  PDF  |  HTML  |  Order a Reprint

Novel PARP1/2 inhibitor mefuparib hydrochloride elicits potent in vitro and in vivo anticancer activity, characteristic of high tissue distribution

Novel PARP1/2 inhibitor mefuparib hydrochloride elicits potent in vitro and in vivo anticancer activity, characteristic of high tissue distribution

https://doi.org/10.18632/oncotarget.13749

Jin-Xue He, Meng Wang, Xia-Juan Huan, Chuan-Huizi Chen, Shan-Shan Song, Ying-Qing Wang, Xue-Mei Liao, Cun Tan, Qian He, Lin-Jiang Tong, Yu-Ting Wang, Xiao-Hua Li, Yi Su, Yan-Yan Shen, Yi-Ming Sun, Xin-Ying Yang, Yi Chen, Zhi-Wei Gao, Xiao-Yan Chen, Bing Xiong, Xiu-Lian Lu, Jian Ding, Chun-Hao Yang,  and Ze-Hong Miao
4156-4168
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Decline in arylsulfatase B leads to increased invasiveness of melanoma cells

Decline in arylsulfatase B leads to increased invasiveness of melanoma cells

https://doi.org/10.18632/oncotarget.13751

Sumit Bhattacharyya, Leo Feferman, Kaoru Terai, Arkadiusz Z. Dudek,  and Joanne K. Tobacman
4169-4180
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Paradoxical induction of growth arrest and apoptosis by EGF via the up-regulation of PTEN by activating Redox factor-1/Egr-1 in human lung cancer cells

Paradoxical induction of growth arrest and apoptosis by EGF via the up-regulation of PTEN by activating Redox factor-1/Egr-1 in human lung cancer cells

https://doi.org/10.18632/oncotarget.13809

Je-won Ryu, Sung Sik Choe, Seung-Hee Ryu, Eun-Young Park, Byoung Wook Lee, Tae Keun Kim, Chang Hoon Ha,  and Sang-wook Lee
4181-4195
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Andrographolide impedes cancer stemness and enhances radio-sensitivity in oral carcinomas via miR-218 activation

Andrographolide impedes cancer stemness and enhances radio-sensitivity in oral carcinomas via miR-218 activation

https://doi.org/10.18632/oncotarget.13755

Po-Yu Yang, Pei-Ling Hsieh, Tong Hong Wang, Cheng-Chia Yu, Ming-Yi Lu, Yi-Wen Liao, Tzu-Hsin Lee,  and Chih-Yu Peng
4196-4207
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

iRNA-AI: identifying the adenosine to inosine editing sites in RNA sequences

iRNA-AI: identifying the adenosine to inosine editing sites in RNA sequences

https://doi.org/10.18632/oncotarget.13758

Wei Chen, Pengmian Feng, Hui Yang, Hui Ding, Hao Lin,  and Kuo-Chen Chou
4208-4217
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HabibTM 4X-assisted resection versus clamp-crush resection for hepatocellular carcinoma: a propensity-matching study

HabibTM 4X-assisted resection versus clamp-crush resection for hepatocellular carcinoma: a propensity-matching study

https://doi.org/10.18632/oncotarget.13906

Jiliang Qiu, Weiqun Lu, Nanrong Yu, Guohua Yang, Yi Li, Zhiliang Huang, Jianchang Li, Kefei Li, Houwei Xu, Shicai Chen, Xiang Zeng,  and Haiying Liu
4218-4227
Abstract  |  PDF  |  HTML  |  Order a Reprint

IL1R1 gene polymorphisms are associated with knee osteoarthritis risk in the Chinese Han population

IL1R1 gene polymorphisms are associated with knee osteoarthritis risk in the Chinese Han population

https://doi.org/10.18632/oncotarget.13935

Yuyan Na, Rui Bai, Zhenqun Zhao, Yishan Wei, Daihe Li, Yong Wang, Chao Sun, Liang Sun, Bolun Zhang, Tianbo Jin,  and Wanlin Liu
4228-4233
Abstract  |  PDF  |  HTML  |  Order a Reprint

Relation between baseline plaque features and subsequent coronary artery remodeling determined by optical coherence tomography and intravascular ultrasound

Relation between baseline plaque features and subsequent coronary artery remodeling determined by optical coherence tomography and intravascular ultrasound

https://doi.org/10.18632/oncotarget.13959

Zulong Xie, Nana Dong, Rong Sun, Xinxin Liu, Xia Gu, Yong Sun, Hongwei Du, Jiannan Dai, Youbin Liu, Jingbo Hou, Jinwei Tian,  and Bo Yu
4234-4244
Abstract  |  PDF  |  HTML  |  Order a Reprint

Increased body mass index is associated with improved overall survival in extranodal natural killer/T-cell lymphoma, nasal type

Increased body mass index is associated with improved overall survival in extranodal natural killer/T-cell lymphoma, nasal type

https://doi.org/10.18632/oncotarget.13988

Ya-Jun Li, Ping-Yong Yi, Ji-Wei Li, Xian-Ling Liu, Xi-Yu Liu, Fang Zhou, Zhou OuYang, Zhong-Yi Sun, Li-Jun Huang, Jun-Qiao He, Yuan Yao, Zhou Fan, Tian Tang,  and Wen-Qi Jiang
4245-4256
Abstract  |  PDF  |  HTML  |  Order a Reprint

The pre-existing population of 5S rRNA effects p53 stabilization during ribosome biogenesis inhibition

The pre-existing population of 5S rRNA effects p53 stabilization during ribosome biogenesis inhibition

https://doi.org/10.18632/oncotarget.13833

Carmine Onofrillo, Alice Galbiati, Lorenzo Montanaro,  and Massimo Derenzini
4257-4267
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression of PSMA in tumor neovasculature of high grade sarcomas including synovial sarcoma, rhabdomyosarcoma, undifferentiated sarcoma and MPNST

Expression of PSMA in tumor neovasculature of high grade sarcomas including synovial sarcoma, rhabdomyosarcoma, undifferentiated sarcoma and MPNST

https://doi.org/10.18632/oncotarget.13994

Birthe Heitkötter, Marcel Trautmann, Inga Grünewald, Martin Bögemann, Kambiz Rahbar, Heidrun Gevensleben, Eva Wardelmann, Wolfgang Hartmann, Konrad Steinestel,  and Sebastian Huss
4268-4276
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells

Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells

https://doi.org/10.18632/oncotarget.13834

Albert Bosch-Vilaró, Bart Jacobs, Valentina Pomella, Layka Abbasi Asbagh, Richard Kirkland, Joe Michel, Sharat Singh, Xinjun Liu, Phillip Kim, Gregory Weitsman, Paul R Barber, Borivoj Vojnovic, Tony Ng,  and Sabine Tejpar
4277-4288
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preoperatively staging liver fibrosis using noninvasive method in Hepatitis B virus-infected hepatocellular carcinoma patients

Preoperatively staging liver fibrosis using noninvasive method in Hepatitis B virus-infected hepatocellular carcinoma patients

https://doi.org/10.18632/oncotarget.14024

Hengyi Gao, Feng Zhu, Min Wang, Hang Zhang, Dawei Ye, Jiayin Yang, Li Jiang, Chang Liu, Renyi Qin, Lunan Yan,  and Guangqin Xiao
4289-4300
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic value of combined preoperative fibrinogen and neutrophil-lymphocyte ratio in patients with hepatocellular carcinoma after liver transplantation

Prognostic value of combined preoperative fibrinogen and neutrophil-lymphocyte ratio in patients with hepatocellular carcinoma after liver transplantation

https://doi.org/10.18632/oncotarget.13804

Shun-Jun Fu, Fei Ji, Ming Han, Mao-Gen Chen, Xiao-Ping Wang, Wei-Qiang Ju, Qiang Zhao, Lin-Wei Wu, Qing-Qi Ren, Zhi-Yong Guo, Dong-Ping Wang, Xiao-Feng Zhu, Yi Ma,  and Xiao-Shun He
4301-4312
Abstract  |  PDF  |  HTML  |  Order a Reprint

MSH2/BRCA1 expression as a DNA-repair signature predicting survival in early–stage lung cancer patients from the IFCT-0002 Phase 3 Trial

MSH2/BRCA1 expression as a DNA-repair signature predicting survival in early–stage lung cancer patients from the IFCT-0002 Phase 3 Trial

https://doi.org/10.18632/oncotarget.14025

Guénaëlle Levallet, Fatéméh Dubois, Pierre Fouret, Martine Antoine, Solenn Brosseau, Emmanuel Bergot, Michèle Beau-Faller, Valérie Gounant, Elisabeth Brambilla, Didier Debieuvre, Olivier Molinier, Françoise Galateau-Sallé, Julien Mazieres, Elisabeth Quoix, Jean-Louis Pujol, Denis Moro-Sibilot, Alexandra Langlais, Franck Morin, Virginie Westeel,  and Gérard Zalcman
4313-4329
Abstract  |  PDF  |  HTML  |  Order a Reprint

Structurally related odorant ligands of the olfactory receptor OR51E2 differentially promote metastasis emergence and tumor growth

Structurally related odorant ligands of the olfactory receptor OR51E2 differentially promote metastasis emergence and tumor growth

https://doi.org/10.18632/oncotarget.13836

Guenhaël Sanz, Isabelle Leray, Denise Grébert, Sharmilee Antoine, Adrien Acquistapace, Adeline Muscat, Abdelhak Boukadiri,  and Lluis M. Mir
4330-4341
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Outcomes of surgery for gastric cancer with distant metastases: a retrospective study from the SEER database

Outcomes of surgery for gastric cancer with distant metastases: a retrospective study from the SEER database

https://doi.org/10.18632/oncotarget.14027

Jia-Qi Chen, Yi-Yao Kong, Shan-Shan Weng, Cai-Xia Dong, Li-Zhen Zhu, ZiRu Yang, Jing Zhong,  and Ying Yuan
4342-4351
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prospective study on factors affecting the prognosis of oral cancer in a Chinese population

Prospective study on factors affecting the prognosis of oral cancer in a Chinese population

https://doi.org/10.18632/oncotarget.13842

Fengqiong Liu, Fa Chen, Jiangfeng Huang, Lingjun Yan, Fangping Liu, Junfeng Wu, Yu Qiu, Xiaoyan Zheng, Rongzhao Zhang, Lisong Lin,  and Baochang He
4352-4359
Abstract  |  PDF  |  HTML  |  Order a Reprint

A multidisciplinary team care approach improves outcomes in high-risk pediatric neuroblastoma patients

A multidisciplinary team care approach improves outcomes in high-risk pediatric neuroblastoma patients

https://doi.org/10.18632/oncotarget.13874

Hsiu-Hao Chang, Yen-Lin Liu, Meng-Yao Lu, Shiann-Tarng Jou, Yung-Li Yang, Dong-Tsamn Lin, Kai-Hsin Lin, Kai-Yuan Tzen, Ruoh-Fang Yen, Ching-Chu Lu, Chia-Ju Liu, Steven Shinn-Forng Peng, Yung-Ming Jeng, Shiu-Feng Huang, Hsinyu Lee, Hsueh-Fen Juan, Min-Chuan Huang, Yung-Feng Liao, Ya-Ling Lee,  and Wen-Ming Hsu
4360-4372
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation

Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation

https://doi.org/10.18632/oncotarget.13875

Sara Lázaro, Miriam Pérez-Crespo, Ana Belén Enguita, Pilar Hernández, Jesús Martínez-Palacio, Marta Oteo, Julien Sage, Jesús M. Paramio,  and Mirentxu Santos
4373-4386
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Meta-prediction of MTHFR gene polymorphism-mutations, air pollution, and risks of leukemia among world populations

Meta-prediction of MTHFR gene polymorphism-mutations, air pollution, and risks of leukemia among world populations

https://doi.org/10.18632/oncotarget.13876

Shin-Yu A. Lien, Lufei Young, Bih-Shya Gau,  and S. Pamela K. Shiao
4387-4398
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeted delivery of chemotherapy using HSP90 inhibitor drug conjugates is highly active against pancreatic cancer models

Targeted delivery of chemotherapy using HSP90 inhibitor drug conjugates is highly active against pancreatic cancer models

https://doi.org/10.18632/oncotarget.12642

Egor Bobrov, Natalia Skobeleva, Diana Restifo, Natalya Beglyarova, Kathy Q. Cai, Elizabeth Handorf, Kerry Campbell, David A. Proia, Vladimir Khazak, Erica A. Golemis,  and Igor Astsaturov
4399-4409
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Growth hormone-releasing hormone antagonist inhibits the invasiveness of human endometrial cancer cells by down-regulating twist and N-cadherin expression

Growth hormone-releasing hormone antagonist inhibits the invasiveness of human endometrial cancer cells by down-regulating twist and N-cadherin expression

https://doi.org/10.18632/oncotarget.13877

Hsien-Ming Wu, Hong-Yuan Huang, Andrew V. Schally, Angel Chao, Hung-Hsueh Chou, Peter C.K. Leung,  and Hsin-Shih Wang
4410-4421
Abstract  |  PDF  |  HTML  |  Order a Reprint

Methylation of promoter of RBL1 enhances the radioresistance of three dimensional cultured carcinoma cells

Methylation of promoter of RBL1 enhances the radioresistance of three dimensional cultured carcinoma cells

https://doi.org/10.18632/oncotarget.12647

Dong Pan, Yaxiong Chen, Yarong Du, Zhenxin Ren, Xiaoman Li,  and Burong Hu
4422-4435
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The function of cancer-shed gangliosides in macrophage phenotype: involvement with angiogenesis

The function of cancer-shed gangliosides in macrophage phenotype: involvement with angiogenesis

https://doi.org/10.18632/oncotarget.13878

Tae-Wook Chung, Hee-Jung Choi, Mi-Ju Park, Hee-Jin Choi, Syng-Ook Lee, Keuk-Jun Kim, Cheorl-Ho Kim, Changwan Hong, Kyun-Ha Kim, Myungsoo Joo,  and Ki-Tae Ha
4436-4448
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GABARAPL1 suppresses metastasis by counteracting PI3K/Akt pathway in prostate cancer

GABARAPL1 suppresses metastasis by counteracting PI3K/Akt pathway in prostate cancer

https://doi.org/10.18632/oncotarget.13879

Wei Su, Shibao Li, Xiaofan Chen, Lingyu Yin, Ping Ma, Yingyu Ma,  and Bing Su
4449-4459
Abstract  |  PDF  |  HTML  |  Order a Reprint

Association between the HOTAIR polymorphisms and cancer risk: an updated meta-analysis

Association between the HOTAIR polymorphisms and cancer risk: an updated meta-analysis

https://doi.org/10.18632/oncotarget.13880

Zhao-Xiong Zhang, Xue Tong, Wan-Ni Zhang,  and Wei-Neng Fu
4460-4470
Abstract  |  PDF  |  HTML  |  Order a Reprint

Opposing roles of KIT and ABL1 in the therapeutic response of gastrointestinal stromal tumor (GIST) cells to imatinib mesylate

Opposing roles of KIT and ABL1 in the therapeutic response of gastrointestinal stromal tumor (GIST) cells to imatinib mesylate

https://doi.org/10.18632/oncotarget.13882

Jessica L. Rausch, Sergei Boichuk, Areej A. Ali, Sneha S. Patil, Lijun Liu, Donna M. Lee, Matthew F. Brown, Kathleen R. Makielski, Ying Liu, Takahiro Taguchi, Shih-Fan Kuan,  and Anette Duensing
4471-4483
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

An oncogenic KRAS transcription program activates the RHOGEF ARHGEF2 to mediate transformed phenotypes in pancreatic cancer

An oncogenic KRAS transcription program activates the RHOGEF ARHGEF2 to mediate transformed phenotypes in pancreatic cancer

https://doi.org/10.18632/oncotarget.13152

Oliver A. Kent, María-José Sandí, Helen E. Burston, Kevin R. Brown,  and Robert Rottapel
4484-4500
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The transcription levels and prognostic values of seven proteasome alpha subunits in human cancers

The transcription levels and prognostic values of seven proteasome alpha subunits in human cancers

https://doi.org/10.18632/oncotarget.13885

Yunhai Li, Jing Huang, Jiazheng Sun, Shili Xiang, Dejuan Yang, Xuedong Ying, Mengqi Lu, Hongzhong Li,  and Guosheng Ren
4501-4519
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Potent CD4+ T cell-associated antitumor memory responses induced by trifunctional bispecific antibodies in combination with immune checkpoint inhibition

Potent CD4+ T cell-associated antitumor memory responses induced by trifunctional bispecific antibodies in combination with immune checkpoint inhibition

https://doi.org/10.18632/oncotarget.13888

Nina Deppisch, Peter Ruf, Nina Eißler, Horst Lindhofer,  and Ralph Mocikat
4520-4529
Abstract  |  PDF  |  HTML  |  Order a Reprint

Ameloblastoma RNA profiling uncovers a distinct non-coding RNA signature

Ameloblastoma RNA profiling uncovers a distinct non-coding RNA signature

https://doi.org/10.18632/oncotarget.13889

Haleh Davanian, Anangi Balasiddaiah, Robert Heymann, Magnus Sundström, Poppy Redenström, Mikael Silfverberg, David Brodin, Matti Sällberg, Sven Lindskog, Carina Kruger Weiner,  and Margaret Chen
4530-4542
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High expression of Snail and NF-κB predicts poor survival in Chinese hepatocellular carcinoma patients

High expression of Snail and NF-κB predicts poor survival in Chinese hepatocellular carcinoma patients

https://doi.org/10.18632/oncotarget.13891

Min Zhang, Xin Dong, Dengcai Zhang, Xiaojie Chen,  and Xinyu Zhu
4543-4548
Abstract  |  PDF  |  HTML  |  Order a Reprint

LHBs can elevate the expression of MDR1 through HIF-1α in patients with CHB infection: a comparative proteomic study

LHBs can elevate the expression of MDR1 through HIF-1α in patients with CHB infection: a comparative proteomic study

https://doi.org/10.18632/oncotarget.13941

Shiying Li, Yixuan Yang, Xiangchun Ding, Min Yang, Sha She, Hong Peng, Xiaoming Xu, Xiaoping Ran, Sanglin Li, Peng Hu, Huaidong Hu, Dazhi Zhang,  and Hong Ren
4549-4562
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The prognostic value of node status in different breast cancer subtypes

The prognostic value of node status in different breast cancer subtypes

https://doi.org/10.18632/oncotarget.13943

Zheng-Jun Yang, Yue Yu, Xin-Wei Hou, Jiang-Rui Chi, Jie Ge, Xin Wang,  and Xu-Chen Cao
4563-4571
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-30e reduces cell growth and enhances drug sensitivity to gefitinib in lung carcinoma

MicroRNA-30e reduces cell growth and enhances drug sensitivity to gefitinib in lung carcinoma

https://doi.org/10.18632/oncotarget.13944

Zhi-Qiang Ning, Hai-lin Lu, Chao Chen, Lin Wang, Wei Cai, Yan Li, Ting-hua Cao, Jing Zhu, Yong-Qian Shu,  and Hua Shen
4572-4581
Abstract  |  PDF  |  HTML  |  Order a Reprint

Mesenchymal marker expression is elevated in Müller cells exposed to high glucose and in animal models of diabetic retinopathy

Mesenchymal marker expression is elevated in Müller cells exposed to high glucose and in animal models of diabetic retinopathy

https://doi.org/10.18632/oncotarget.13945

Ti Zhou, Di Che, Yuqing Lan, Zhenzhen Fang, Jinye Xie, HaiJun Gong, ChaoYang Li, Juan Feng, Honghai Hong, Weiwei Qi, Caiqi Ma, Zhonghan Yang, WeiBin Cai, Jun Zhong, Jianxing Ma, Xia Yang,  and Guoquan Gao
4582-4594
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genome-wide analysis of differentially expressed lncRNAs and mRNAs in primary gonadotrophin adenomas by RNA-seq

Genome-wide analysis of differentially expressed lncRNAs and mRNAs in primary gonadotrophin adenomas by RNA-seq

https://doi.org/10.18632/oncotarget.13948

Jiye Li, Chuzhong Li, Jianpeng Wang, Guidong Song, Zheng Zhao, Haoyuan Wang, Wen Wang, Hailong Li, Zhenye Li, Yazhou Miao, Guilin Li,  and Yazhuo Zhang
4595-4606
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Co-expression of Piwil2/Piwil4 in nucleus indicates poor prognosis of hepatocellular carcinoma

Co-expression of Piwil2/Piwil4 in nucleus indicates poor prognosis of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.13491

Guangping Zeng, Deying Zhang, Xing Liu, Qing Kang, Yiyao Fu, Bo Tang, Wenhao Guo, Yuanyuan Zhang, Guanghui Wei,  and Dawei He
4607-4617
Abstract  |  PDF  |  HTML  |  Order a Reprint

Tyrosine kinase fusion genes in pediatric BCR-ABL1-like acute lymphoblastic leukemia

Tyrosine kinase fusion genes in pediatric BCR-ABL1-like acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.13492

Judith M. Boer, Elisabeth M.P. Steeghs, João R.M. Marchante, Aurélie Boeree, James J. Beaudoin, H. Berna Beverloo, Roland P. Kuiper, Gabriele Escherich, Vincent H.J. van der Velden, C. Ellen van der Schoot, A. de Groot- Kruseman, Rob Pieters,  and Monique L. den Boer
4618-4628
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-182 drives colonization and macroscopic metastasis via targeting its suppressor SNAI1 in breast cancer

MicroRNA-182 drives colonization and macroscopic metastasis via targeting its suppressor SNAI1 in breast cancer

https://doi.org/10.18632/oncotarget.13542

Yun Zhan, Xukun Li, Xiaoshuan Liang, Lin Li, Bangrong Cao, Baona Wang, Jianlin Ma, Fang Ding, Xiang Wang, Da Pang,  and Zhihua Liu
4629-4641
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Improved method for prioritization of disease associated lncRNAs based on ceRNA theory and functional genomics data

Improved method for prioritization of disease associated lncRNAs based on ceRNA theory and functional genomics data

https://doi.org/10.18632/oncotarget.13964

Peng Wang, Qiuyan Guo, Yue Gao, Hui Zhi, Yan Zhang, Yue Liu, Jizhou Zhang, Ming Yue, Maoni Guo, Shangwei Ning, Guangmei Zhang,  and Xia Li
4642-4655
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Effects of lipopolysaccharide on maturation of bovine oocyte in vitro and its possible mechanisms

Effects of lipopolysaccharide on maturation of bovine oocyte in vitro and its possible mechanisms

https://doi.org/10.18632/oncotarget.13965

Shan-Jiang Zhao, Yun-Wei Pang, Xue-Ming Zhao, Wei-Hua Du, Hai-Sheng Hao,  and Hua-Bin Zhu
4656-4667
Abstract  |  PDF  |  HTML  |  Order a Reprint

Long non-coding RNA urothelial carcinoma associated 1 (UCA1) mediates radiation response in prostate cancer

Long non-coding RNA urothelial carcinoma associated 1 (UCA1) mediates radiation response in prostate cancer

https://doi.org/10.18632/oncotarget.13576

Alireza Fotouhi Ghiam, Samira Taeb, Xiaoyong Huang, Vincent Huang, Jessica Ray, Seville Scarcello, Christianne Hoey, Sahar Jahangiri, Emmanouil Fokas, Andrew Loblaw, Robert G. Bristow, Danny Vesprini, Paul Boutros,  and Stanley K. Liu
4668-4689
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Autocrine IL-6 mediates pituitary tumor senescence

Autocrine IL-6 mediates pituitary tumor senescence

https://doi.org/10.18632/oncotarget.13577

Melanie Sapochnik, Mariana R. Haedo, Mariana Fuertes, Pablo Ajler, Guillermo Carrizo, Andrés Cervio, Gustavo Sevlever, Günter K. Stalla,  and Eduardo Arzt
4690-4702
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sodium fluoride (NaF) causes toxic effects on splenic development in mice

Sodium fluoride (NaF) causes toxic effects on splenic development in mice

https://doi.org/10.18632/oncotarget.13971

Ping Kuang, Huidan Deng, Hengmin Cui, Lian Chen, Jing Fang, Zhicai Zuo, Junliang Deng, Xun Wang,  and Ling Zhao
4703-4717
Abstract  |  PDF  |  HTML  |  Order a Reprint

Synthesis of a cell penetrating peptide modified superparamagnetic iron oxide and MRI detection of bladder cancer

Synthesis of a cell penetrating peptide modified superparamagnetic iron oxide and MRI detection of bladder cancer

https://doi.org/10.18632/oncotarget.13578

Chen Ding, Kaijie Wu, Weiyi Wang, Zhenfeng Guan, Lei wang, Xinyang Wang, Rong Wang, Li Liu,  and Jinhai Fan
4718-4729
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oncolytic adenovirus coexpressing interleukin-12 and decorin overcomes Treg-mediated immunosuppression inducing potent antitumor effects in a weakly immunogenic tumor model

Oncolytic adenovirus coexpressing interleukin-12 and decorin overcomes Treg-mediated immunosuppression inducing potent antitumor effects in a weakly immunogenic tumor model

https://doi.org/10.18632/oncotarget.13972

Eonju Oh, Il-Kyu Choi, JinWoo Hong,  and Chae-Ok Yun
4730-4746
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The miR-196b miRNA inhibits the GATA6 intestinal transcription factor and is upregulated in colon cancer patients

The miR-196b miRNA inhibits the GATA6 intestinal transcription factor and is upregulated in colon cancer patients

https://doi.org/10.18632/oncotarget.13580

Sebastian Fantini, Valentina Salsi, Luca Reggiani, Antonino Maiorana,  and Vincenzo Zappavigna
4747-4759
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Rituximab-conjugated, doxorubicin-loaded microbubbles as a theranostic modality in B-cell lymphoma

Rituximab-conjugated, doxorubicin-loaded microbubbles as a theranostic modality in B-cell lymphoma

https://doi.org/10.18632/oncotarget.13587

Shoubing Zhou, Xiu Zhang,  and Cailian Wang
4760-4772
Abstract  |  PDF  |  HTML  |  Order a Reprint

The different outcomes between breast-conserving surgery and mastectomy in triple-negative breast cancer: a population-based study from the SEER 18 database

The different outcomes between breast-conserving surgery and mastectomy in triple-negative breast cancer: a population-based study from the SEER 18 database

https://doi.org/10.18632/oncotarget.13976

Qing-Xia Chen, Xiao-Xiao Wang, Pei-Yang Lin, Jie Zhang, Jun-Jing Li, Chuan-Gui Song,  and Zhi-Ming Shao
4773-4780
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Aspirin and non-steroidal anti-inflammatory drugs use reduce gastric cancer risk: A dose-response meta-analysis

Aspirin and non-steroidal anti-inflammatory drugs use reduce gastric cancer risk: A dose-response meta-analysis

https://doi.org/10.18632/oncotarget.13591

Xuan-zhang Huang, You Chen, Jian Wu, Xi Zhang, Cong-cong Wu, Chao-ying Zhang, Shuang-shuang Sun,  and Wen-jun Chen
4781-4795
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Osthole protects sepsis-induced acute kidney injury via down-regulating NF-κB signal pathway

Osthole protects sepsis-induced acute kidney injury via down-regulating NF-κB signal pathway

https://doi.org/10.18632/oncotarget.13592

Chen Yu, Peng Li, Dong Qi, Lei Wang, Hong-lin Qu, Yue-juan Zhang, Xue-kai Wang,  and Hua-Ying Fan
4796-4813
Abstract  |  PDF  |  HTML  |  Order a Reprint

IL-17A weakens the antitumor immuity by inhibiting apoptosis of MDSCs in Lewis lung carcinoma bearing mice

IL-17A weakens the antitumor immuity by inhibiting apoptosis of MDSCs in Lewis lung carcinoma bearing mice

https://doi.org/10.18632/oncotarget.13978

Juan Wang, Yue Zhang, Kai Yin, Peiqi Xu, Jie Tian, Jie Ma, Xinyu Tian, Yungang Wang, Xinyi Tang, Huaxi Xu,  and Shengjun Wang
4814-4825
Abstract  |  PDF  |  HTML  |  Order a Reprint

Stromal p16 expression is significantly increased in endometrial carcinoma

Stromal p16 expression is significantly increased in endometrial carcinoma

https://doi.org/10.18632/oncotarget.13594

Gun Yoon, Chang Won Koh, Nara Yoon, Ji-Ye Kim,  and Hyun-Soo Kim
4826-4836
Abstract  |  PDF  |  HTML  |  Order a Reprint

Astragalus polysaccharide restores autophagic flux and improves cardiomyocyte function in doxorubicin-induced cardiotoxicity

Astragalus polysaccharide restores autophagic flux and improves cardiomyocyte function in doxorubicin-induced cardiotoxicity

https://doi.org/10.18632/oncotarget.13596

Yuan Cao, Tao Shen, Xiuqing Huang, Yajun Lin, Beidong Chen, Jing Pang, Guoping Li, Que Wang, Sylvia Zohrabian, Chao Duan, Yang Ruan, Yong Man, Shu Wang,  and Jian Li
4837-4848
Abstract  |  PDF  |  HTML  |  Order a Reprint

IL-23R mutation is associated with ulcerative colitis: A systemic review and meta-analysis

IL-23R mutation is associated with ulcerative colitis: A systemic review and meta-analysis

https://doi.org/10.18632/oncotarget.13607

Ling-Long Peng, Ying Wang, Feng-Ling Zhu, Wang-Dong Xu, Xue-Lei Ji,  and Jing Ni
4849-4863
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Induction of specific T helper-9 cells to inhibit glioma cell growth

Induction of specific T helper-9 cells to inhibit glioma cell growth

https://doi.org/10.18632/oncotarget.13981

Haiyan Zheng, Baohua Yang, Dedong Xu, Wenbo Wang, Jie Tan, Liyuan Sun, Qinghua Li, Li Sun,  and Xuewei Xia
4864-4874
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Androgen receptor phosphorylation status at serine 578 predicts poor outcome in prostate cancer patients

Androgen receptor phosphorylation status at serine 578 predicts poor outcome in prostate cancer patients

https://doi.org/10.18632/oncotarget.13608

Patek SC, Willder JM, Heng JS, Taylor B, Horgan PG, Leung HY, Underwood MA,  and Edwards J
4875-4887
Abstract  |  PDF  |  HTML  |  Order a Reprint

Sprouty2 correlates with favorable prognosis of gastric adenocarcinoma via suppressing FGFR2-induced ERK phosphorylation and cancer progression

Sprouty2 correlates with favorable prognosis of gastric adenocarcinoma via suppressing FGFR2-induced ERK phosphorylation and cancer progression

https://doi.org/10.18632/oncotarget.13982

Yunfei Xu, Xiaoqing Yang, Zhen Li, Shuo Li, Sen Guo, Sayed Ismail, Hongda Liu, Zhihong Huang, Zongli Zhang, Yuxin Chen,  and Qing Sun
4888-4900
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Depletion of mitochondrial reactive oxygen species downregulates epithelial-to-mesenchymal transition in cervical cancer cells

Depletion of mitochondrial reactive oxygen species downregulates epithelial-to-mesenchymal transition in cervical cancer cells

https://doi.org/10.18632/oncotarget.13612

Galina Shagieva, Lidiya Domnina, Olga Makarevich, Boris Chernyak, Vladimir Skulachev,  and Vera Dugina
4901-4913
Abstract  |  PDF  |  HTML  |  Order a Reprint

ED-B fibronectin expression is a marker of epithelial-mesenchymal transition in translational oncology

ED-B fibronectin expression is a marker of epithelial-mesenchymal transition in translational oncology

https://doi.org/10.18632/oncotarget.13615

Iacopo Petrini, Serena Barachini, Vittoria Carnicelli, Sara Galimberti, Letizia Modeo, Roberto Boni, Martina Sollini,  and Paola Anna Erba
4914-4921
Abstract  |  PDF  |  HTML  |  Order a Reprint

Effect of 3q oncogenes SEC62 and SOX2 on lymphatic metastasis and clinical outcome of head and neck squamous cell carcinomas

Effect of 3q oncogenes SEC62 and SOX2 on lymphatic metastasis and clinical outcome of head and neck squamous cell carcinomas

https://doi.org/10.18632/oncotarget.13986

Florian Bochen, Hana Adisurya, Silke Wemmert, Cornelia Lerner, Markus Greiner, Richard Zimmermann, Andrea Hasenfus, Mathias Wagner, Sigrun Smola, Thorsten Pfuhl, Alessandro Bozzato, Basel Al Kadah, Bernhard Schick,  and Maximilian Linxweiler
4922-4934
Abstract  |  PDF  |  HTML  |  Order a Reprint

Survival outcomes and surgical intervention of small intestinal neuroendocrine tumors: a population based retrospective study

Survival outcomes and surgical intervention of small intestinal neuroendocrine tumors: a population based retrospective study

https://doi.org/10.18632/oncotarget.13632

Lunpo Wu, Jianfei Fu, Li Wan, Jie Pan, Sanchuan Lai, Jing Zhong, Daniel C. Chung,  and Liangjing Wang
4935-4947
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Quality measurement on shear wave speed imaging: diagnostic value in differentiation of thyroid malignancy and the associated factors

Quality measurement on shear wave speed imaging: diagnostic value in differentiation of thyroid malignancy and the associated factors

https://doi.org/10.18632/oncotarget.13996

Bo-Ji Liu, Chong-Ke Zhao, Hui-Xiong Xu, Yi-Feng Zhang, Jun-Mei Xu, Dan-Dan Li, Xiao-Wan Bo,  and Xiao-Long Li
4948-4959
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeted proteomics in urinary extracellular vesicles identifies biomarkers for diagnosis and prognosis of prostate cancer

Targeted proteomics in urinary extracellular vesicles identifies biomarkers for diagnosis and prognosis of prostate cancer

https://doi.org/10.18632/oncotarget.13634

Tamara Sequeiros, Marina Rigau, Cristina Chiva, Melania Montes, Iolanda Garcia-Grau, Marta Garcia, Sherley Diaz, Ana Celma, Irene Bijnsdorp, Alex Campos, Primiano Di Mauro, Salvador Borrós, Jaume Reventós, Andreas Doll, Rosanna Paciucci, Michiel Pegtel, Inés de Torres, Eduard Sabidó, Juan Morote,  and Mireia Olivan
4960-4976
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CDH1 regulates E2F1 degradation in response to differentiation signals in keratinocytes

CDH1 regulates E2F1 degradation in response to differentiation signals in keratinocytes

https://doi.org/10.18632/oncotarget.13636

Randeep K. Singh,  and Lina Dagnino
4977-4993
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The role of T790M mutation in EGFR-TKI re-challenge for patients with EGFR-mutant advanced lung adenocarcinoma

The role of T790M mutation in EGFR-TKI re-challenge for patients with EGFR-mutant advanced lung adenocarcinoma

https://doi.org/10.18632/oncotarget.14007

Qiuyi Zhang, Ee Ke, Feiyu Niu, Wei Deng, Zhihong Chen, Chongrui Xu, Xuchao Zhang, Ning Zhao, Jian Su, Jinji Yang, Honghong Yan, Yilong Wu,  and Qing Zhou
4994-5002
Abstract  |  PDF  |  HTML  |  Order a Reprint

Concomitant inhibition of receptor tyrosine kinases and downstream AKT synergistically inhibited growth of KRAS/BRAF mutant colorectal cancer cells

Concomitant inhibition of receptor tyrosine kinases and downstream AKT synergistically inhibited growth of KRAS/BRAF mutant colorectal cancer cells

https://doi.org/10.18632/oncotarget.14009

Qiaoling Song, Xiaoxiao Sun, Hui Guo,  and Qiang Yu
5003-5015
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identifying the clonal origin of synchronous multifocal tumors in the hepatobiliary and pancreatic system using multi-omic platforms

Identifying the clonal origin of synchronous multifocal tumors in the hepatobiliary and pancreatic system using multi-omic platforms

https://doi.org/10.18632/oncotarget.14018

Weiqin Jiang, Yongfeng Ding, Yifei Shen, Longjiang Fan, Linfu Zhou, Zhi Li, Yi Zheng, Peng Zhao, Lulu Liu, Zhou Tong, Weijia Fang,  and Weilin Wang
5016-5025
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mael is essential for cancer cell survival and tumorigenesis through protection of genetic integrity

Mael is essential for cancer cell survival and tumorigenesis through protection of genetic integrity

https://doi.org/10.18632/oncotarget.13756

Su-Hyeon Kim, Eun-Ran Park, Eugene Cho, Won-Hee Jung, Ju-Yeon Jeon, Hyun-Yoo Joo, Kee-Ho Lee,  and Hyun-Jin Shin
5026-5037
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Diagnostic and prognostic value of miR-106a in colorectal cancer

Diagnostic and prognostic value of miR-106a in colorectal cancer

https://doi.org/10.18632/oncotarget.13766

Haibin Hao, Laipeng Liu, Dong Zhang, Chao Wang, Guangfeng Xia, Fuping Zhong,  and Xiaoyun Hu
5038-5047
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FOXD3 is a tumor suppressor of colon cancer by inhibiting EGFR-Ras-Raf-MEK-ERK signal pathway

FOXD3 is a tumor suppressor of colon cancer by inhibiting EGFR-Ras-Raf-MEK-ERK signal pathway

https://doi.org/10.18632/oncotarget.13790

Kun Li, Qunfeng Guo, Jun Yang, Hui Chen, Kewen Hu, Juan Zhao, Xiufeng Pang, Sufang Zhou, Yongyan Dang,  and Lei Li
5048-5056
Abstract  |  PDF  |  HTML  |  Order a Reprint

MiR-433-3p suppresses cell growth and enhances chemosensitivity by targeting CREB in human glioma

MiR-433-3p suppresses cell growth and enhances chemosensitivity by targeting CREB in human glioma

https://doi.org/10.18632/oncotarget.13789

Shupeng Sun, Xiuyu Wang, Xinnv Xu, Hui Di, Jixiang Du, Bin Xu, Qiong Wang,  and Jinhuan Wang
5057-5068
Abstract  |  PDF  |  HTML  |  Order a Reprint

Genome wide copy number analyses of superficial esophageal squamous cell carcinoma with and without metastasis

Genome wide copy number analyses of superficial esophageal squamous cell carcinoma with and without metastasis

https://doi.org/10.18632/oncotarget.13847

Pengjiao Wang, Ling Shan, Liyan Xue, Bo Zheng, Jianming Ying,  and Ning Lu
5069-5080
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Are neurological complications of monoclonal gammopathy of undetermined significance underestimated?

Are neurological complications of monoclonal gammopathy of undetermined significance underestimated?

https://doi.org/10.18632/oncotarget.13861

Normann Steiner, Angelika Schwärzler, Georg Göbel, Wolfgang Löscher, Julia Wanschitz,  and Eberhard Gunsilius
5081-5091
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cancer upregulated gene 2 induces epithelial-mesenchymal transition of human lung cancer cells via TGF-β signaling

Cancer upregulated gene 2 induces epithelial-mesenchymal transition of human lung cancer cells via TGF-β signaling

https://doi.org/10.18632/oncotarget.13867

Sirichat Kaowinn, Jeonghyo Kim, Jaebeom Lee, Dong Hoon Shin, Chi-Dug Kang, Dae-Kee Kim, Soojin Lee, Min Kyung Kang, Sang Seok Koh, Seong-Jin Kim,  and Young-Hwa Chung
5092-5110
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Macrophage production and activation are dependent on TRIM33

Macrophage production and activation are dependent on TRIM33

https://doi.org/10.18632/oncotarget.13872

Anne-Sophie Gallouet, Federica Ferri, Vanessa Petit, Aude Parcelier, Daniel Lewandowski, Nathalie Gault, Vilma Barroca, Stéphanie Le Gras, Eric Soler, Frank Grosveld, Irwin Davidson,  and Paul-Henri Romeo
5111-5122
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of TRPC6 reduces non-small cell lung cancer cell proliferation and invasion

Inhibition of TRPC6 reduces non-small cell lung cancer cell proliferation and invasion

https://doi.org/10.18632/oncotarget.14034

Li-Li Yang, Bing-Chen Liu, Xiao-Yu Lu, Yan Yan, Yu-Jia Zhai, Qing Bao, Paul W. Doetsch, Xingming Deng, Tiffany L. Thai, Abdel A. Alli, Douglas C. Eaton, Bao-Zhong Shen,  and He-Ping Ma
5123-5134
Abstract  |  PDF  |  HTML  |  Order a Reprint

CCL24 contributes to HCC malignancy via RhoB- VEGFA-VEGFR2 angiogenesis pathway and indicates poor prognosis

CCL24 contributes to HCC malignancy via RhoB- VEGFA-VEGFR2 angiogenesis pathway and indicates poor prognosis

https://doi.org/10.18632/oncotarget.14095

Lei Jin, Wei-Ren Liu, Meng-Xin Tian, Xi-Fei Jiang, Han Wang, Pei-Yun Zhou, Zhen-Bin Ding, Yuan-Fei Peng, Zhi Dai, Shuang-Jian Qiu, Jian Zhou, Jia Fan,  and Ying-Hong Shi
5135-5148
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

An ensemble approach for large-scale identification of protein- protein interactions using the alignments of multiple sequences

An ensemble approach for large-scale identification of protein- protein interactions using the alignments of multiple sequences

https://doi.org/10.18632/oncotarget.14103

Lei Wang, Zhu-Hong You, Xing Chen, Jian-Qiang Li, Xin Yan, Wei Zhang,  and Yu-An Huang
5149-5159
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High throughput estimation of functional cell activities reveals disease mechanisms and predicts relevant clinical outcomes

High throughput estimation of functional cell activities reveals disease mechanisms and predicts relevant clinical outcomes

https://doi.org/10.18632/oncotarget.14107

Marta R. Hidalgo, Cankut Cubuk, Alicia Amadoz, Francisco Salavert, José Carbonell-Caballero,  and Joaquin Dopazo
5160-5178
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Peptide-guided targeting of GPR55 for anti-cancer therapy

Peptide-guided targeting of GPR55 for anti-cancer therapy

https://doi.org/10.18632/oncotarget.14121

Maria Mangini, Enrico Iaccino, Maria Giovanna Mosca, Selena Mimmi, Rosa D’Angelo, Ileana Quinto, Giuseppe Scala,  and Stefania Mariggiò
5179-5195
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genomic differences between black and white patients implicate a distinct immune response to papillary renal cell carcinoma

Genomic differences between black and white patients implicate a distinct immune response to papillary renal cell carcinoma

https://doi.org/10.18632/oncotarget.14122

David J. Paulucci, John P. Sfakianos, Anders J. Skanderup, Kathleen Kan, Che-Kai Tsao, Matthew D. Galsky, A. Ari Hakimi,  and Ketan K. Badani
5196-5205
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-200c is a cMyc-activated miRNA that promotes nasopharyngeal carcinoma by downregulating PTEN

MiR-200c is a cMyc-activated miRNA that promotes nasopharyngeal carcinoma by downregulating PTEN

https://doi.org/10.18632/oncotarget.14123

Pan Chen, Xiaofang Guo, Liming Zhang, Wenling Zhang, Qingyu Zhou, Zhi Tian, Ying Zheng, Qianjin Liao, Heran Wang, Guiyuan Li, Jin Huang,  and Xiayu Li
5206-5218
Abstract  |  PDF  |  HTML  |  Order a Reprint

Tumor-infiltrating lymphocytes predict prognosis of breast cancer patients treated with anti-Her-2 therapy

Tumor-infiltrating lymphocytes predict prognosis of breast cancer patients treated with anti-Her-2 therapy

https://doi.org/10.18632/oncotarget.14124

Tan-Huan Chen, Ying-Chun Zhang, Yu-Ting Tan, Xin An, Cong Xue, Ying-Fei Deng, Wei Yang, Xia Yuan,  and Yan-Xia Shi
5219-5232
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The pseudogene DUXAP10 promotes an aggressive phenotype through binding with LSD1 and repressing LATS2 and RRAD in non small cell lung cancer

The pseudogene DUXAP10 promotes an aggressive phenotype through binding with LSD1 and repressing LATS2 and RRAD in non small cell lung cancer

https://doi.org/10.18632/oncotarget.14125

Chen-Chen Wei, Feng-Qi Nie, Li-Li Jiang, Qin-Nan Chen, Zhen-Yao Chen, Xin Chen, Xuan Pan, Zhi-Li Liu, Bin-Bin Lu,  and Zhao-Xia Wang
5233-5246
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Antitumor effect of an adeno-associated virus expressing apolipoprotein A-1 fused to interferon alpha in an interferon alpha-resistant murine tumor model

Antitumor effect of an adeno-associated virus expressing apolipoprotein A-1 fused to interferon alpha in an interferon alpha-resistant murine tumor model

https://doi.org/10.18632/oncotarget.14127

Marcos Vasquez, Vladimir Paredes-Cervantes, Fernando Aranda, Nuria Ardaiz, Celia Gomar,  and Pedro Berraondo
5247-5255
Abstract  |  PDF  |  HTML  |  Order a Reprint

ABCG2 confers promotion in gastric cancer through modulating downstream CRKL in vitro combining with biostatistics mining

ABCG2 confers promotion in gastric cancer through modulating downstream CRKL in vitro combining with biostatistics mining

https://doi.org/10.18632/oncotarget.14128

Junqing Wang, Zhou Yunyun, Lu Wang, Xuehua Chen,  and Zhenggang Zhu
5256-5267
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identifying prognostic biomarkers based on aberrant DNA methylation in kidney renal clear cell carcinoma

Identifying prognostic biomarkers based on aberrant DNA methylation in kidney renal clear cell carcinoma

https://doi.org/10.18632/oncotarget.14134

Guang Chen, Yihan Wang, Lu Wang,  and Wanhai Xu
5268-5280
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Low lymphocyte-to-white blood cell ratio and high monocyte-to-white blood cell ratio predict poor prognosis in gastric cancer

Low lymphocyte-to-white blood cell ratio and high monocyte-to-white blood cell ratio predict poor prognosis in gastric cancer

https://doi.org/10.18632/oncotarget.14136

Fan Feng, Li Sun, Gaozan Zheng, Shushang Liu, Zhen Liu, Guanghui Xu, Man Guo, Xiao Lian, Daiming Fan,  and Hongwei Zhang
5281-5291
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostication of serial post-intensity-modulated radiation therapy undetectable plasma EBV DNA for nasopharyngeal carcinoma

Prognostication of serial post-intensity-modulated radiation therapy undetectable plasma EBV DNA for nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.14137

Victor Ho-Fun Lee, Dora Lai-Wan Kwong, To-Wai Leung, Cheuk-Wai Choi, Vincent Lai, Lydia Ng Ka-On Lam, Sherry Chor-Yi Ng, Chun-Kin Sze, Chi-Chung Tong, Patty Pui-Ying Ho, Wing-Lok Chan, Lai-San Wong, Dennis Kwok-Chuen Leung, Sum-Yin Chan,  and Pek-Lan Khong
5292-5308
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Phenotypic characterization of circulating tumor cells in triple negative breast cancer patients

Phenotypic characterization of circulating tumor cells in triple negative breast cancer patients

https://doi.org/10.18632/oncotarget.14144

Sofia Agelaki, Melina Dragolia, Harris Markonanolaki, Saad Alkahtani, Christos Stournaras, Vassilis Georgoulias,  and Galatea Kallergi
5309-5322
Abstract  |  PDF  |  HTML  |  Order a Reprint

Knockdown of RNF2 induces cell cycle arrest and apoptosis in prostate cancer cells through the upregulation of TXNIP

Knockdown of RNF2 induces cell cycle arrest and apoptosis in prostate cancer cells through the upregulation of TXNIP

https://doi.org/10.18632/oncotarget.14142

Ming Wei, Dian Jiao, Donghui Han, Jieheng Wu, Feilong Wei, Guoxu Zheng, Zhangyan Guo, Wenjin Xi, Fa Yang, Pin Xie, Lingling Zhang, An-Gang Yang, He Wang, Weijun Qin,  and Weihong Wen
5323-5338
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Regional hyperthermia combined with radiotherapy for esophageal squamous cell carcinoma with supraclavicular lymph node metastasis

Regional hyperthermia combined with radiotherapy for esophageal squamous cell carcinoma with supraclavicular lymph node metastasis

https://doi.org/10.18632/oncotarget.14148

Sheng Liming, Ji Yongling, Wu Qiner,  and Du Xianghui
5339-5348
Abstract  |  PDF  |  HTML  |  Order a Reprint

Guidance to rational use of pharmaceuticals in gallbladder sarcomatoid carcinoma using patient-derived cancer cells and whole exome sequencing

Guidance to rational use of pharmaceuticals in gallbladder sarcomatoid carcinoma using patient-derived cancer cells and whole exome sequencing

https://doi.org/10.18632/oncotarget.14146

Feiling Feng, Qingbao Cheng, Liang Yang, Dadong Zhang, Shunlong Ji, Qiangzu Zhang, Yihui Lin, Fugen Li, Lei Xiong, Chen Liu,  and Xiaoqing Jiang
5349-5360
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epstein-Barr virus EBNA2 directs doxorubicin resistance of B cell lymphoma through CCL3 and CCL4-mediated activation of NF-κB and Btk

Epstein-Barr virus EBNA2 directs doxorubicin resistance of B cell lymphoma through CCL3 and CCL4-mediated activation of NF-κB and Btk

https://doi.org/10.18632/oncotarget.14243

Joo Hyun Kim, Won Seog Kim, Jung Yong Hong, Kyungju Ryu, Seok Jin Kim,  and Chaehwa Park
5361-5370
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combining vasculature disrupting agent and toll-like receptor 7/8 agonist for cancer therapy

Combining vasculature disrupting agent and toll-like receptor 7/8 agonist for cancer therapy

https://doi.org/10.18632/oncotarget.14260

Anushree Seth, Hyunseung Lee, Mi Young Cho, Cheongsoo Park, Sovannarith Korm, Joo-Yong Lee, Inpyo Choi, Yong Taik Lim,  and Kwan Soo Hong
5371-5381
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevated YKL-40 expression is associated with a poor prognosis in breast cancer patients

Elevated YKL-40 expression is associated with a poor prognosis in breast cancer patients

https://doi.org/10.18632/oncotarget.14280

Guoxing Wa, Longchao Xiang, Xue Sun, Xuanbin Wang, Hongliang Li, Wei Ge,  and Fengjun Cao
5382-5391
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Chemoembolization of liver cancer with drug-loading microsphere 50-100μm

Chemoembolization of liver cancer with drug-loading microsphere 50-100μm

https://doi.org/10.18632/oncotarget.14281

Jun-Hui Sun, Guan-Hui Zhou, Yue-Lin Zhang, Chun-Hui Nie, Tan-Yang Zhou, Jing Ai, Tong-Yin Zhu, Wei-Lin Wang,  and Shu-Sen Zheng
5392-5399
Abstract  |  PDF  |  HTML  |  Order a Reprint

Nerve growth factor-induced Akt/mTOR activation protects the ischemic heart via restoring autophagic flux and attenuating ubiquitinated protein accumulation

Nerve growth factor-induced Akt/mTOR activation protects the ischemic heart via restoring autophagic flux and attenuating ubiquitinated protein accumulation

https://doi.org/10.18632/oncotarget.14284

Zhou-Guang Wang, Hao Li, Yan Huang, Rui Li, Xiao-Fan Wang, Li-Xia Yu, Xue-qiang Guang, Lei Li, Hong-Yu Zhang, Ying-Zheng Zhao, Chunxiang Zhang, Xiao-Kun Li, Rong-Zhou Wu, Mao-Ping Chu,  and Jian Xiao
5400-5413
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Lymphocyte-to-monocyte ratio is associated with prognosis of diffuse large B-cell lymphoma: correlation with CD163 positive M2 type tumor-associated macrophages, not PD-1 positive tumor-infiltrating lymphocytes

Lymphocyte-to-monocyte ratio is associated with prognosis of diffuse large B-cell lymphoma: correlation with CD163 positive M2 type tumor-associated macrophages, not PD-1 positive tumor-infiltrating lymphocytes

https://doi.org/10.18632/oncotarget.14289

Jingxuan Wang, Kun Gao, Wanting Lei, Lina Dong, Qijia Xuan, Meiyan Feng, Jinlu Wang, Xiangnan Ye, Tuan Jin, Zhongbai Zhang,  and Qingyuan Zhang
5414-5425
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Chemotherapy can induce weight normalization of morbidly obese mice despite undiminished ingestion of high fat diet

Chemotherapy can induce weight normalization of morbidly obese mice despite undiminished ingestion of high fat diet

https://doi.org/10.18632/oncotarget.14576

Cheryl E. Myers, Dominique B. Hoelzinger, Tiffany N. Truong, Lindsey A. Chew, Arpita Myles, Leena Chaudhuri, Jan B. Egan, Jun Liu, Sandra J. Gendler,  and Peter A. Cohen
5426-5438
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Improving needle biopsy accuracy in small renal mass using tumor-specific DNA methylation markers

Improving needle biopsy accuracy in small renal mass using tumor-specific DNA methylation markers

https://doi.org/10.18632/oncotarget.12276

Sameer Chopra, Jie Liu, Mehrdad Alemozaffar, Peter W. Nichols, Manju Aron, Daniel J. Weisenberger, Clayton K. Collings, Sumeet Syan, Brian Hu, Mihir Desai, Monish Aron, Vinay Duddalwar, Inderbir Gill, Gangning Liang,  and Kimberly D. Siegmund
5439-5448
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Correlation analysis between 2D and quasi-3D gamma evaluations for both intensity-modulated radiation therapy and volumetric modulated arc therapy

Correlation analysis between 2D and quasi-3D gamma evaluations for both intensity-modulated radiation therapy and volumetric modulated arc therapy

https://doi.org/10.18632/oncotarget.12279

Jung-in Kim, Chang Heon Choi, Hong-Gyun Wu, Jin Ho Kim, Kyubo Kim,  and Jong Min Park
5449-5459
Abstract  |  PDF  |  HTML  |  Order a Reprint

A mixed analysis comparing nine minimally invasive surgeries for unresectable hepatocellular carcinoma patients

A mixed analysis comparing nine minimally invasive surgeries for unresectable hepatocellular carcinoma patients

https://doi.org/10.18632/oncotarget.12348

Ran Tao, Xiaodan Li, Ruizhi Ran, Zhihua Xiao, Hongyue Zhang, Hongyan Kong, Qiqin Song, Yu Huang, Likui Wang,  and Jiaquan Huang
5460-5473
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic value of a novel risk classification of microvascular invasion in patients with hepatocellular carcinoma after resection

Prognostic value of a novel risk classification of microvascular invasion in patients with hepatocellular carcinoma after resection

https://doi.org/10.18632/oncotarget.12547

Hui Zhao, Chuang Chen, Xu Fu, Xiaopeng Yan, Wenjun Jia, Liang Mao, Huihan Jin,  and Yudong Qiu
5474-5486
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Design and implementation of a mobile system for lung cancer patient follow-up in China and initial report of the ongoing patient registry

Design and implementation of a mobile system for lung cancer patient follow-up in China and initial report of the ongoing patient registry

https://doi.org/10.18632/oncotarget.13720

Xiangyun Ye, Jia Wei, Ziming Li, Xiaomin Niu, Jiemin Wang, Yunqin Chen, Zongming Guo,  and Shun Lu
5487-5497
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reviews

Role of an imbalanced miRNAs axis in pathogenesis of psoriasis: novel perspectives based on review of the literature

Role of an imbalanced miRNAs axis in pathogenesis of psoriasis: novel perspectives based on review of the literature

https://doi.org/10.18632/oncotarget.12534

Mao-Jie Wang, Yong-Yue Xu, Run-Yue Huang, Xiu-Min Chen, Hai-Ming Chen, Ling Han, Yu-Hong Yan,  and Chuan-Jian Lu
5498-5507
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dysregulation of long non-coding RNA in breast cancer: an overview of mechanism and clinical implication

Dysregulation of long non-coding RNA in breast cancer: an overview of mechanism and clinical implication

https://doi.org/10.18632/oncotarget.12537

Ji Wang, Chenyang Ye, Hanchu Xiong, Yong Shen, Yi Lu, Jichun Zhou,  and Linbo Wang
5508-5522
Abstract  |  PDF  |  HTML  |  Order a Reprint

Potential approaches to the treatment of Ewing’s sarcoma

Potential approaches to the treatment of Ewing’s sarcoma

https://doi.org/10.18632/oncotarget.12566

Hongjiu Yu, Yonggui Ge, Lianying Guo,  and Lin Huang
5523-5539
Abstract  |  PDF  |  HTML  |  Order a Reprint

Tyrosine kinase inhibitors and mesenchymal stromal cells: effects on self-renewal, commitment and functions

Tyrosine kinase inhibitors and mesenchymal stromal cells: effects on self-renewal, commitment and functions

https://doi.org/10.18632/oncotarget.12649

Adriana Borriello, Ilaria Caldarelli, Debora Bencivenga, Emanuela Stampone, Silverio Perrotta, Adriana Oliva,  and Fulvio Della Ragione
5540-5565
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic gene expression profiling in esophageal cancer: a systematic review

Prognostic gene expression profiling in esophageal cancer: a systematic review

https://doi.org/10.18632/oncotarget.13328

Els Visser, Ingrid A. Franken, Lodewijk A.A. Brosens, Jelle P. Ruurda,  and Richard van Hillegersberg
5566-5577
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mammographic density: a potential monitoring biomarker for adjuvant and preventative breast cancer endocrine therapies

Mammographic density: a potential monitoring biomarker for adjuvant and preventative breast cancer endocrine therapies

https://doi.org/10.18632/oncotarget.13484

Michael S. Shawky, Hilary Martin, Honor J. Hugo, Thomas Lloyd, Kara L. Britt, Andrew Redfern,  and Erika W. Thompson
5578-5591
Abstract  |  PDF  |  HTML  |  Order a Reprint

Tetraspanin CD151 as an emerging potential poor prognostic factor across solid tumors: a systematic review and meta-analysis

Tetraspanin CD151 as an emerging potential poor prognostic factor across solid tumors: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.13532

Ping Zeng, Yin-Hua Wang, Meng Si, Jin-Hua Gu, Ping Li, Pei-Hua Lu,  and Min-Bin Chen
5592-5602
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeting the VEGF-C/VEGFR3 axis suppresses Slug-mediated cancer metastasis and stemness via inhibition of KRAS/YAP1 signaling

Targeting the VEGF-C/VEGFR3 axis suppresses Slug-mediated cancer metastasis and stemness via inhibition of KRAS/YAP1 signaling

https://doi.org/10.18632/oncotarget.13629

Yu-Wen Yeh, Ching-Chia Cheng, Shu-Ting Yang, Chi-Feng Tseng, Ting-Yu Chang, Sin-Ying Tsai, Earl Fu, Chien-Ping Chiang, Li-Chuan Liao, Pei-Wen Tsai, Yung-Luen Yu,  and Jen-Liang Su
5603-5618
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Anti-tumor activity of metformin: from metabolic and epigenetic perspectives

Anti-tumor activity of metformin: from metabolic and epigenetic perspectives

https://doi.org/10.18632/oncotarget.13639

Xilan Yu, Wuxiang Mao, Yansheng Zhai, Chong Tong, Min Liu, Lixin Ma, Xiaolan Yu,  and Shanshan Li
5619-5628
Abstract  |  PDF  |  HTML  |  Order a Reprint

Whole genome DNA methylation: beyond genes silencing

Whole genome DNA methylation: beyond genes silencing

https://doi.org/10.18632/oncotarget.13562

Roberto Tirado-Magallanes, Khadija Rebbani, Ricky Lim, Sriharsa Pradhan,  and Touati Benoukraf
5629-5637
Abstract  |  PDF  |  HTML  |  Order a Reprint

Corrections

Correction: Pharmacologic targeting of the PI3K/mTOR pathway controls release of angioregulators from primary human acute myeloid leukemia cells and their neighboring stromal cells

Correction: Pharmacologic targeting of the PI3K/mTOR pathway controls release of angioregulators from primary human acute myeloid leukemia cells and their neighboring stromal cells

https://doi.org/10.18632/oncotarget.14676

Håkon Reikvam, Ina Nepstad, Øystein Bruserud,  and Kimberley Joanne Hatfield
5638-5639
Correction  |  PDF

News

Weight loss effects of methotrexate and cyclophosphamide

Weight loss effects of methotrexate and cyclophosphamide

https://doi.org/10.18632/oncotarget.14569

Dave Bridges
5640
PDF  |  Order a Reprint


Copyright © 2017 Impact Journals
Impact Journals is a registered trademark of Impact Journals, LLC