Oncotarget

Vol 8, No 1

January 3, 2017

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About The Cover

The cover for issue 1 of Oncotarget features Figure 3, ‘Loss of USP18 expression decreased cytoplasmic PTEN protein,’ from Mustachio, et al

Table of Contents

Editorial: Autophagy and Cell Death

RIPK1 prevents aberrant ZBP1-initiated necroptosis

RIPK1 prevents aberrant ZBP1-initiated necroptosis

https://doi.org/10.18632/oncotarget.13926

Tom Vanden Berghe,  and William J. Kaiser
1-2
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Priority Research Papers

The ISG15-specific protease USP18 regulates stability of PTEN

The ISG15-specific protease USP18 regulates stability of PTEN

https://doi.org/10.18632/oncotarget.13914

Lisa Maria Mustachio, Masanori Kawakami, Yun Lu, Jaime Rodriguez-Canales, Barbara Mino, Carmen Behrens, Ignacio Wistuba, Neus Bota-Rabassedas, Jun Yu, J. Jack Lee, Jason Roszik, Lin Zheng, Xi Liu, Sarah J. Freemantle,  and Ethan Dmitrovsky
3-14
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Research Papers: Gerotarget (Focus on Aging)

MicroRNA expressing profiles in A53T mutant alpha-synuclein transgenic mice and Parkinsonian

MicroRNA expressing profiles in A53T mutant alpha-synuclein transgenic mice and Parkinsonian

https://doi.org/10.18632/oncotarget.13905

Mingshu Mo, Yousheng Xiao, Shuxuan Huang, Luan Cen, Xiang Chen, Limin Zhang, Qin Luo, Shaomin Li, Xinling Yang, Xian Lin,  and Pingyi Xu
15-28
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Influence of aging on the activity of mice Sca-1+CD31 cardiac stem cells

Influence of aging on the activity of mice Sca-1+CD31 cardiac stem cells

https://doi.org/10.18632/oncotarget.13930

Qiong Wu, Jinxi Zhan, Shiming Pu, Liu Qin, Yun Li,  and Zuping Zhou
29-41
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How does white matter microstructure differ between the vascular and amnestic mild cognitive impairment?

How does white matter microstructure differ between the vascular and amnestic mild cognitive impairment?

https://doi.org/10.18632/oncotarget.13960

Yang Yu, Xinyu Liang, Haikuo Yu, Weina Zhao, Yan Lu, Yue Huang, Changhao Yin, Gaolang Gong,  and Ying Han
42-50
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Research Papers: Pathology

Characterization of IFNγ-producing natural killer cells induced by cytomegalovirus reactivation after haploidentical hematopoietic stem cell transplantation

Characterization of IFNγ-producing natural killer cells induced by cytomegalovirus reactivation after haploidentical hematopoietic stem cell transplantation

https://doi.org/10.18632/oncotarget.13916

Fengyan Jin, Hai Lin, Sujun Gao, Hengxiang Wang, Hongmin Yan, Jinglong Guo, Zheng Hu, Chunhui Jin, Yongqi Wang, Zhidong Wang, Yangzhi Zhao, Yu Liu, Xiaoli Zheng, Yehui Tan, Wei Li, Yun Dai,  and Yanping Yang
51-63
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Gastric acid response to acute exposure to hypergravity

Gastric acid response to acute exposure to hypergravity

https://doi.org/10.18632/oncotarget.13969

Gun Yoon,  and Hyun-Soo Kim
64-69
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Research Papers: Immunology

High salt diet stimulates gut Th17 response and exacerbates TNBS-induced colitis in mice

High salt diet stimulates gut Th17 response and exacerbates TNBS-induced colitis in mice

https://doi.org/10.18632/oncotarget.13783

Yingfeng Wei, Chong Lu, Jianing Chen, Guangying Cui, Lin Wang, Tianming Yu, Yue Yang, Wei Wu, Yulong Ding, Lanjuan Li, Toshimitsu Uede, Zhi Chen,  and Hongyan Diao
70-82
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Critical role of SP thymocyte motility in regulation of thymic output in neonatal Aire-/- mice

Critical role of SP thymocyte motility in regulation of thymic output in neonatal Aire-/- mice

https://doi.org/10.18632/oncotarget.13909

Rong Jin, Abudureyimujiang Aili, Yuqing Wang, Jia Wu, Xiuyuan Sun, Yu Zhang,  and Qing Ge
83-94
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Berberine augments ATP-induced inflammasome activation in macrophages by enhancing AMPK signaling

Berberine augments ATP-induced inflammasome activation in macrophages by enhancing AMPK signaling

https://doi.org/10.18632/oncotarget.13921

Chen-Guang Li, Liang Yan, Yan-Yun Jing, Li-Hui Xu, Yi-Dan Liang, Hong-Xia Wei, Bo Hu, Hao Pan, Qing-Bing Zha, Dong-Yun Ouyang,  and Xian-Hui He
95-109
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Research Papers

Improving risk stratification of patients with childhood acute lymphoblastic leukemia: Glutathione-S-Transferases polymorphisms are associated with increased risk of relapse

Improving risk stratification of patients with childhood acute lymphoblastic leukemia: Glutathione-S-Transferases polymorphisms are associated with increased risk of relapse

https://doi.org/10.18632/oncotarget.8606

Daiana B. Leonardi, Mercedes Abbate, María C. Riccheri, Myriam Nuñez, Graciela Alfonso, Geraldine Gueron, Adriana De Siervi, Elba Vazquez,  and Javier Cotignola
110-117
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Zoledronic acid impairs stromal reactivity by inhibiting M2-macrophages polarization and prostate cancer-associated fibroblasts

Zoledronic acid impairs stromal reactivity by inhibiting M2-macrophages polarization and prostate cancer-associated fibroblasts

https://doi.org/10.18632/oncotarget.9497

Giuseppina Comito, Coral Pons Segura, Maria Letizia Taddei, Michele Lanciotti, Sergio Serni, Andrea Morandi, Paola Chiarugi,  and Elisa Giannoni
118-132
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Differentiated regulation of immune-response related genes between LUAD and LUSC subtypes of lung cancers

Differentiated regulation of immune-response related genes between LUAD and LUSC subtypes of lung cancers

https://doi.org/10.18632/oncotarget.13346

Mengzhu Chen, Xiuying Liu, Jie Du, Xiu-Jie Wang,  and Lixin Xia
133-144
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Non-myogenic tumors display altered expression of dystrophin (DMD) and a high frequency of genetic alterations

Non-myogenic tumors display altered expression of dystrophin (DMD) and a high frequency of genetic alterations

https://doi.org/10.18632/oncotarget.10426

Leonela N. Luce, Mercedes Abbate, Javier Cotignola,  and Florencia Giliberto
145-155
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Prognostic impact of MYH9 expression on patients with acute myeloid leukemia

Prognostic impact of MYH9 expression on patients with acute myeloid leukemia

https://doi.org/10.18632/oncotarget.10613

Mengxia Yu, Jinghan Wang, Zhijuan Zhu, Chao Hu, Qiuling Ma, Xia Li, Xiufeng Yin, Jiansong Huang, Ting Zhang, Zhixin Ma, Yile Zhou, Chenying Li, Feifei Chen, Jian Chen, Yungui Wang, Hanzhang Pan, Dongmei Wang,  and Jie Jin
156-163
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4-Hydroxyestradiol induces mammary epithelial cell transformation through Nrf2-mediated heme oxygenase-1 overexpression

4-Hydroxyestradiol induces mammary epithelial cell transformation through Nrf2-mediated heme oxygenase-1 overexpression

https://doi.org/10.18632/oncotarget.10516

Sin-Aye Park, Mee-Hyun Lee, Hye-Kyung Na,  and Young-Joon Surh
164-178
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Kras mutations increase telomerase activity and targeting telomerase is a promising therapeutic strategy for Kras-mutant NSCLC

Kras mutations increase telomerase activity and targeting telomerase is a promising therapeutic strategy for Kras-mutant NSCLC

https://doi.org/10.18632/oncotarget.10162

Weiran Liu, Yuesong Yin, Jun Wang, Bowen Shi, Lianmin Zhang, Dong Qian, Chenguang Li, Hua Zhang, Shengguang Wang, Jinfang Zhu, Liuwei Gao, Qiang Zhang, Bin Jia, Ligang Hao, Changli Wang,  and Bin Zhang
179-190
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IGFBP2 expression predicts IDH-mutant glioma patient survival

IGFBP2 expression predicts IDH-mutant glioma patient survival

https://doi.org/10.18632/oncotarget.13329

Lin Eric Huang, Adam L. Cohen, Howard Colman, Randy L. Jensen, Daniel W. Fults,  and William T. Couldwell
191-202
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Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrett’s-like esophagus

Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrett’s-like esophagus

https://doi.org/10.18632/oncotarget.10667

Yoomi Lee, Aleksandra M. Urbanska, Yoku Hayakawa, Hongshan Wang, Andrew S. Au, Aesis M. Luna, Wenju Chang, Guangchun Jin, Govind Bhagat, Julian A. Abrams, Richard A. Friedman, Andrea Varro, Kenneth K. Wang, Malcolm Boyce, Anil K. Rustgi, Antonia R. Sepulveda, Michael Quante,  and Timothy C. Wang
203-214
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VE-cadherin RGD motifs promote metastasis and constitute a potential therapeutic target in melanoma and breast cancers

VE-cadherin RGD motifs promote metastasis and constitute a potential therapeutic target in melanoma and breast cancers

https://doi.org/10.18632/oncotarget.13832

Rubén A. Bartolomé, Sofía Torres, Soledad Isern de Val, Beatriz Escudero-Paniagua, Eva Calviño, Joaquín Teixidó,  and J. Ignacio Casal
215-227
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Looking for the best anti-colitis medicine: A comparative analysis of current and prospective compounds

Looking for the best anti-colitis medicine: A comparative analysis of current and prospective compounds

https://doi.org/10.18632/oncotarget.13894

Anastasiya A. Chumanevich, Anusha Chaparala, Erin E. Witalison, Hossam Tashkandi, Anne B. Hofseth, Corey Lane, Edsel Pena, Piaomu Liu, Doug L. Pittman, Prakash Nagarkatti, Mitzi Nagarkatti, Lorne J. Hofseth,  and Alexander A. Chumanevich
228-237
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

BRAF-activated LncRNA functions as a tumor suppressor in papillary thyroid cancer

BRAF-activated LncRNA functions as a tumor suppressor in papillary thyroid cancer

https://doi.org/10.18632/oncotarget.10825

Tian Liao, Ning Qu, Rong-Liang Shi, Kai Guo, Ben Ma, Yi-Ming Cao, Jun Xiang, Zhong-Wu Lu, Yong-Xue Zhu, Duan-Shu Li,  and Qing-Hai Ji
238-247
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Quinacrine induces apoptosis in cancer cells by forming a functional bridge between TRAIL-DR5 complex and modulating the mitochondrial intrinsic cascade

Quinacrine induces apoptosis in cancer cells by forming a functional bridge between TRAIL-DR5 complex and modulating the mitochondrial intrinsic cascade

https://doi.org/10.18632/oncotarget.11335

Sarita Das, Neha Tripathi, Ranjan Preet, Sumit Siddharth, Anmada Nayak, Prasad V. Bharatam,  and Chanakya Nath Kundu
248-267
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Impacts of cigarette smoking on immune responsiveness: Up and down or upside down?

Impacts of cigarette smoking on immune responsiveness: Up and down or upside down?

https://doi.org/10.18632/oncotarget.13613

Feifei Qiu, Chun-Ling Liang, Huazhen Liu, Yu-Qun Zeng, Shaozhen Hou, Song Huang, Xiaoping Lai,  and Zhenhua Dai
268-284
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Prognostic significance of BRCA mutations in ovarian cancer: an updated systematic review with meta-analysis

Prognostic significance of BRCA mutations in ovarian cancer: an updated systematic review with meta-analysis

https://doi.org/10.18632/oncotarget.12306

Kai Xu, Shouhua Yang,  and Yingchao Zhao
285-302
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Prognostic value of increased KPNA2 expression in some solid tumors: A systematic review and meta-analysis

Prognostic value of increased KPNA2 expression in some solid tumors: A systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.13863

Li-Na Zhou, Yue Tan, Ping Li, Ping Zeng, Min-Bin Chen, Ye Tian,  and Ya-Qun Zhu
303-314
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Epigenetic silencing of TET2 and TET3 induces an EMT-like process in melanoma

Epigenetic silencing of TET2 and TET3 induces an EMT-like process in melanoma

https://doi.org/10.18632/oncotarget.13324

Fuxing Gong, Yu Guo, Yiqian Niu, Jiawei Jin, Xiaojuan Zhang, Xiaoqian Shi, Limeng Zhang, Runting Li, Longxin Chen,  and Runlin Z. Ma
315-328
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Arctigenin inhibits STAT3 and exhibits anticancer potential in human triple-negative breast cancer therapy

Arctigenin inhibits STAT3 and exhibits anticancer potential in human triple-negative breast cancer therapy

https://doi.org/10.18632/oncotarget.13393

Tingting Feng, Wei Cao, Wanxiang Shen, Liang Zhang, Xinsheng Gu, Yang Guo, Hsiang-i Tsai, Xuewen Liu, Jian Li, Jingxuan Zhang, Shan Li, Fuyun Wu,  and Ying Liu
329-344
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Paradoxes in thyroid carcinoma treatment: analysis of the SEER database 2010-2013

Paradoxes in thyroid carcinoma treatment: analysis of the SEER database 2010-2013

https://doi.org/10.18632/oncotarget.13395

Ping Zhou, Shuangming Tian, Jiale Li, Yongfeng Zhao, Wengang Liu, Yan Zhang,  and Zheyu Hu
345-353
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

AAV-Mediated angiotensin 1-7 overexpression inhibits tumor growth of lung cancer in vitro and in vivo

AAV-Mediated angiotensin 1-7 overexpression inhibits tumor growth of lung cancer in vitro and in vivo

https://doi.org/10.18632/oncotarget.13396

Xinglu Chen, Sansan Chen, Nana Pei, Yingying Mao, Shengyao Wang, Renhe Yan, Na Bai, Andrew Li, Yanling Zhang, Hongyan Du, Baihong Chen, Colin Sumners, Jinlong Li,  and Hongwei Li
354-363
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Epithelial derived-matrix metalloproteinase (MMP9) exhibits a novel defensive role of tumor suppressor in colitis associated cancer by activating MMP9-Notch1-ARF-p53 axis

Epithelial derived-matrix metalloproteinase (MMP9) exhibits a novel defensive role of tumor suppressor in colitis associated cancer by activating MMP9-Notch1-ARF-p53 axis

https://doi.org/10.18632/oncotarget.13406

Lewins Walter, Adani Pujada, Noopur Bhatnagar, Agnieszka B Bialkowska, Vincent W. Yang, Hamed Laroui,  and Pallavi Garg
364-378
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Deletion of 8p is an independent prognostic parameter in prostate cancer

Deletion of 8p is an independent prognostic parameter in prostate cancer

https://doi.org/10.18632/oncotarget.13425

Martina Kluth, Nina Nadine Amschler, Rami Galal, Christina Möller-Koop, Phillipp Barrow, Maria Christina Tsourlakis, Frank Jacobsen, Andrea Hinsch, Corinna Wittmer, Stefan Steurer, Till Krech, Franziska Büscheck, Till Sebastian Clauditz, Burkhard Beyer, Waldemar Wilczak, Markus Graefen, Hartwig Huland, Sarah Minner, Thorsten Schlomm, Guido Sauter,  and Ronald Simon
379-392
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association between three functional microRNA polymorphisms (miR-499 rs3746444, miR-196a rs11614913 and miR-146a rs2910164) and breast cancer risk: a meta-analysis

Association between three functional microRNA polymorphisms (miR-499 rs3746444, miR-196a rs11614913 and miR-146a rs2910164) and breast cancer risk: a meta-analysis

https://doi.org/10.18632/oncotarget.13426

Hong Zhang, Yafei Zhang, Wanjun Yan, Wen Wang, Xixi Zhao, Xingcong Ma, Xiaoyan Gao,  and Shuqun Zhang
393-407
Abstract  |  PDF  |  HTML  |  Order a Reprint

Hepatic resection after transarterial chemoembolization increases overall survival in large/multifocal hepatocellular carcinoma: a retrospective cohort study

Hepatic resection after transarterial chemoembolization increases overall survival in large/multifocal hepatocellular carcinoma: a retrospective cohort study

https://doi.org/10.18632/oncotarget.13427

Junwei Chen, Lisha Lai, Qu Lin, Wensou Huang, Mingyue Cai, Kangshun Zhu,  and Mingsheng Huang
408-417
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Immunological effects of nilotinib prophylaxis after allogeneic stem cell transplantation in patients with advanced chronic myeloid leukemia or philadelphia chromosome-positive acute lymphoblastic leukemia

Immunological effects of nilotinib prophylaxis after allogeneic stem cell transplantation in patients with advanced chronic myeloid leukemia or philadelphia chromosome-positive acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.13439

Nira Varda-Bloom, Ivetta Danylesko, Roni Shouval, Shiran Eldror, Atar Lev, Jacqueline Davidson, Esther Rosenthal, Yulia Volchek, Noga Shem-Tov, Ronit Yerushalmi, Avichai Shimoni, Raz Somech,  and Arnon Nagler
418-429
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeting tachykinin receptors in neuroblastoma

Targeting tachykinin receptors in neuroblastoma

https://doi.org/10.18632/oncotarget.13440

Anton G. Henssen, Andrea Odersky, Annabell Szymansky, Marleen Seiler, Kristina Althoff, Anneleen Beckers, Frank Speleman, Simon Schäfers, Katleen De Preter, Kathy Astrahanseff, Joachim Struck, Alexander Schramm, Angelika Eggert, Andreas Bergmann,  and Johannes H. Schulte
430-443
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Evolutionary biologic changes of gut microbiota in an ‘adenoma-carcinoma sequence’ mouse colorectal cancer model induced by 1, 2-Dimethylhydrazine

Evolutionary biologic changes of gut microbiota in an ‘adenoma-carcinoma sequence’ mouse colorectal cancer model induced by 1, 2-Dimethylhydrazine

https://doi.org/10.18632/oncotarget.13443

Teng Sun, Shanglong Liu, Yanbing Zhou, Zengwu Yao, Dongfeng Zhang, Shougen Cao, Zhiliang Wei, Bin Tan, Yi Li, Zheng Lian,  and Song Wang
444-457
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Tumorigenicity of Ewing sarcoma is critically dependent on the trithorax proteins MLL1 and menin

Tumorigenicity of Ewing sarcoma is critically dependent on the trithorax proteins MLL1 and menin

https://doi.org/10.18632/oncotarget.13444

Laurie K. Svoboda, Natashay Bailey, Raelene A. Van Noord, Melanie A. Krook, Ashley Harris, Cassondra Cramer, Brooke Jasman, Rajiv M. Patel, Dafydd Thomas, Dmitry Borkin, Tomasz Cierpicki, Jolanta Grembecka,  and Elizabeth R. Lawlor
458-471
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miR-103 inhibits proliferation and sensitizes hemopoietic tumor cells for glucocorticoid-induced apoptosis

miR-103 inhibits proliferation and sensitizes hemopoietic tumor cells for glucocorticoid-induced apoptosis

https://doi.org/10.18632/oncotarget.13447

Shlomit Kfir-Erenfeld, Noa Haggiag, Moshe Biton, Polina Stepensky, Nathalie Assayag-Asherie,  and Eitan Yefenof
472-489
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

New bipyridine gold(III) dithiocarbamate-containing complexes exerted a potent anticancer activity against cisplatin-resistant cancer cells independent of p53 status

New bipyridine gold(III) dithiocarbamate-containing complexes exerted a potent anticancer activity against cisplatin-resistant cancer cells independent of p53 status

https://doi.org/10.18632/oncotarget.13448

Muhammad Altaf, Muhammad Monim-ul-Mehboob, Abdel-Nasser Kawde, Giuseppe Corona, Roberto Larcher, Marcia Ogasawara, Naike Casagrande, Marta Celegato, Cinzia Borghese, Zahid H. Siddik, Donatella Aldinucci,  and Anvarhusein A. Isab
490-505
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Is the positivity of estrogen receptor or progesterone receptor different between type 1 and type 2 endometrial cancer?

Is the positivity of estrogen receptor or progesterone receptor different between type 1 and type 2 endometrial cancer?

https://doi.org/10.18632/oncotarget.13471

Fang Shen, Yifei Gao, Jingxin Ding,  and Qi Chen
506-511
Abstract  |  PDF  |  HTML  |  Order a Reprint

Human adipose tissue-derived mesenchymal stem cells alleviate atopic dermatitis via regulation of B lymphocyte maturation

Human adipose tissue-derived mesenchymal stem cells alleviate atopic dermatitis via regulation of B lymphocyte maturation

https://doi.org/10.18632/oncotarget.13473

Tae-Hoon Shin, Byung-Chul Lee, Soon Won Choi, Ji-Hee Shin, Insung Kang, Jin Young Lee, Jae-Jun Kim, Hong-Ki Lee, Jae-Eon Jung, Yong-Woon Choi, Sung-Hoon Lee, Jin-Sang Yoon, Jin-Sub Choi, Chi-Seung Lee, Yoojin Seo, Hyung-Sik Kim,  and Kyung-Sun Kang
512-522
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Pathologic stratification of operable lung adenocarcinoma using radiomics features extracted from dual energy CT images

Pathologic stratification of operable lung adenocarcinoma using radiomics features extracted from dual energy CT images

https://doi.org/10.18632/oncotarget.13476

Jung Min Bae, Ji Yun Jeong, Ho Yun Lee, Insuk Sohn, Hye Seung Kim, Ji Ye Son, O Jung Kwon, Joon Young Choi, Kyung Soo Lee,  and Young Mog Shim
523-535
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression of truncated bile salt-dependent lipase variant in pancreatic pre-neoplastic lesions

Expression of truncated bile salt-dependent lipase variant in pancreatic pre-neoplastic lesions

https://doi.org/10.18632/oncotarget.11777

Emmanuelle Martinez, Isabelle Crenon, Françoise Silvy, Jean Del Grande, Alice Mougel, Dolores Barea, Frederic Fina, Jean-Paul Bernard, Mehdi Ouaissi, Dominique Lombardo,  and Eric Mas
536-551
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Inhibition of the transcriptional repressor complex Bcl-6/BCoR induces endothelial sprouting but does not promote tumor growth

Inhibition of the transcriptional repressor complex Bcl-6/BCoR induces endothelial sprouting but does not promote tumor growth

https://doi.org/10.18632/oncotarget.13477

Elisabeth Buchberger, Dietmar Payrhuber, Miriam El Harchi, Branislav Zagrapan, Katharina Scheuba, Anna Zommer, Edina Bugyik, Balazs Dome, Julia Barbara Kral, Waltraud Cornelia Schrottmaier, Gernot Schabbauer, Peter Petzelbauer, Marion Gröger, Martin Bilban,  and Christine Brostjan
552-564
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

EZH2 overexpression is associated with poor prognosis in patients with glioma

EZH2 overexpression is associated with poor prognosis in patients with glioma

https://doi.org/10.18632/oncotarget.13478

Yanyang Zhang, Xinguang Yu, Ling Chen, Zhibin Zhang,  and Shiyu Feng
565-573
Abstract  |  PDF  |  HTML  |  Order a Reprint

Upregulation of microRNA-524-5p enhances the cisplatin sensitivity of gastric cancer cells by modulating proliferation and metastasis via targeting SOX9

Upregulation of microRNA-524-5p enhances the cisplatin sensitivity of gastric cancer cells by modulating proliferation and metastasis via targeting SOX9

https://doi.org/10.18632/oncotarget.13479

Jing Wang, Xiaofeng Xue, Han Hong, Mingde Qin, Jin Zhou, Qing Sun, Hansi Liang,  and Ling Gao
574-582
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Acquired resistance to BRAF inhibition in BRAFV600E mutant gliomas

Acquired resistance to BRAF inhibition in BRAFV600E mutant gliomas

https://doi.org/10.18632/oncotarget.11882

Tsun-Wen Yao, Jie Zhang, Michael Prados, William A. Weiss, C. David James,  and Theodore Nicolaides
583-595
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Acquired resistance to BRAF inhibition induces epithelial-to-mesenchymal transition in BRAF (V600E) mutant thyroid cancer by c-Met-mediated AKT activation

Acquired resistance to BRAF inhibition induces epithelial-to-mesenchymal transition in BRAF (V600E) mutant thyroid cancer by c-Met-mediated AKT activation

https://doi.org/10.18632/oncotarget.13480

Hyung Kwon Byeon, Hwi Jung Na, Yeon Ju Yang, Sooah Ko, Sun Och Yoon, Minhee Ku, Jaemoon Yang, Jae Wook Kim, Myung Jin Ban, Ji-Hoon Kim, Da Hee Kim, Jung Min Kim, Eun Chang Choi, Chang-Hoon Kim, Joo-Heon Yoon,  and Yoon Woo Koh
596-609
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A polysaccharide from Lentinus edodes inhibits human colon cancer cell proliferation and suppresses tumor growth in athymic nude mice

A polysaccharide from Lentinus edodes inhibits human colon cancer cell proliferation and suppresses tumor growth in athymic nude mice

https://doi.org/10.18632/oncotarget.13481

Jinglin Wang, Weiyong Li, Xiao Huang, Ying Liu, Qiang Li, Ziming Zheng,  and Kaiping Wang
610-623
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TP53 mutations, expression and interaction networks in human cancers

TP53 mutations, expression and interaction networks in human cancers

https://doi.org/10.18632/oncotarget.13483

Xiaosheng Wang,  and Qingrong Sun
624-643
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic and epigenetic silencing of mircoRNA-506-3p enhances COTL1 oncogene expression to foster non-small lung cancer progression

Genetic and epigenetic silencing of mircoRNA-506-3p enhances COTL1 oncogene expression to foster non-small lung cancer progression

https://doi.org/10.18632/oncotarget.13501

Shanqi Guo, Peiying Yang, Xingkang Jiang, Xiaojiang Li, Yuanyuan Wang, Xin Zhang, Binxu Sun, Yao Zhang,  and Yingjie Jia
644-657
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PHACTR1 and SLC22A3 gene polymorphisms are associated with reduced coronary artery disease risk in the male Chinese Han population

PHACTR1 and SLC22A3 gene polymorphisms are associated with reduced coronary artery disease risk in the male Chinese Han population

https://doi.org/10.18632/oncotarget.13506

Qingbin Zhao, Huiyi Wei, Dandan Liu, Baolan Shi, Lei Li, Mengdan Yan, Xiyang Zhang, Fengjiao Wang,  and Yongri Ouyang
658-663
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PTTG1 regulated by miR-146a-3p promotes bladder cancer migration, invasion, metastasis and growth

PTTG1 regulated by miR-146a-3p promotes bladder cancer migration, invasion, metastasis and growth

https://doi.org/10.18632/oncotarget.13507

Wei Xiang, Xinchao Wu, Chao Huang, Miao Wang, Xian Zhao, Gang Luo, Yawei Li, Guosong Jiang, Xingyuan Xiao,  and Fuqing Zeng
664-678
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Accumulated promoter methylation as a potential biomarker for esophageal cancer

Accumulated promoter methylation as a potential biomarker for esophageal cancer

https://doi.org/10.18632/oncotarget.13510

Xianzhen Peng, Hengchuan Xue, Lingshuang Lü, Peiyi Shi, Jianping Wang,  and Jianming Wang
679-691
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cholesterol import and steroidogenesis are biosignatures for gastric cancer patient survival

Cholesterol import and steroidogenesis are biosignatures for gastric cancer patient survival

https://doi.org/10.18632/oncotarget.13524

Wei-Chun Chang, Shang-Fen Huang, Yang-Ming Lee, Hsueh-Chou Lai, Bi-Hua Cheng, Wei-Chung Cheng, Jason Yen-Ping Ho, Long-Bin Jeng,  and Wen-Lung Ma
692-704
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MicroRNA-206 is involved in the pathogenesis of ulcerative colitis via regulation of adenosine A3 receptor

MicroRNA-206 is involved in the pathogenesis of ulcerative colitis via regulation of adenosine A3 receptor

https://doi.org/10.18632/oncotarget.13525

Weiyun Wu, Yanting He, Xiao Feng, Shicai Ye, Hao Wang, Wenkai Tan, Caiyuan Yu, Juxiang Hu, Rong Zheng,  and Yu Zhou
705-721
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Shed urinary ALCAM is an independent prognostic biomarker of three-year overall survival after cystectomy in patients with bladder cancer

Shed urinary ALCAM is an independent prognostic biomarker of three-year overall survival after cystectomy in patients with bladder cancer

https://doi.org/10.18632/oncotarget.13546

Shanna A. Arnold Egloff, Liping Du, Holli A. Loomans, Alina Starchenko, Pei-Fang Su, Tatiana Ketova, Paul B. Knoll, Jifeng Wang, Ahmed Q. Haddad, Oluwole Fadare, Justin M. Cates, Yair Lotan, Yu Shyr, Peter E. Clark,  and Andries Zijlstra
722-741
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of BCR signaling using the Syk inhibitor TAK-659 prevents stroma-mediated signaling in chronic lymphocytic leukemia cells

Inhibition of BCR signaling using the Syk inhibitor TAK-659 prevents stroma-mediated signaling in chronic lymphocytic leukemia cells

https://doi.org/10.18632/oncotarget.13557

Noelia Purroy, Júlia Carabia, Pau Abrisqueta, Leire Egia, Meritxell Aguiló, Cecilia Carpio, Carles Palacio, Marta Crespo,  and Francesc Bosch
742-756
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Toward the development of a novel non-RGD cyclic peptide drug conjugate for treatment of human metastatic melanoma

Toward the development of a novel non-RGD cyclic peptide drug conjugate for treatment of human metastatic melanoma

https://doi.org/10.18632/oncotarget.12748

Boris Redko, Helena Tuchinsky, Tamar Segal, Dror Tobi, Galia Luboshits, Osnat Ashur-Fabian, Albert Pinhasov, Gabi Gerlitz,  and Gary Gellerman
757-768
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ion channels in control of pancreatic stellate cell migration

Ion channels in control of pancreatic stellate cell migration

https://doi.org/10.18632/oncotarget.13647

Hannah Storck, Benedikt Hild, Sandra Schimmelpfennig, Sarah Sargin, Nikolaj Nielsen, Angela Zaccagnino, Thomas Budde, Ivana Novak, Holger Kalthoff,  and Albrecht Schwab
769-784
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Novel risk models for early detection and screening of ovarian cancer

Novel risk models for early detection and screening of ovarian cancer

https://doi.org/10.18632/oncotarget.13648

Matthew R. Russell, Alfonsina D’Amato, Ciaren Graham, Emma J Crosbie, Aleksandra Gentry-Maharaj, Andy Ryan, Jatinderpal K. Kalsi, Evangelia-Ourania Fourkala, Caroline Dive, Michael Walker, Anthony D. Whetton, Usha Menon, Ian Jacobs,  and Robert L.J. Graham
785-797
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dioscin augments HSV-tk-mediated suicide gene therapy for melanoma by promoting connexin-based intercellular communication

Dioscin augments HSV-tk-mediated suicide gene therapy for melanoma by promoting connexin-based intercellular communication

https://doi.org/10.18632/oncotarget.13655

Jianyong Xiao, Guangxian Zhang, Bin Li, Yingya Wu, Xijuan Liu, Yuhui Tan,  and Biaoyan Du
798-807
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circular RNA ZNF609 functions as a competitive endogenous RNA to regulate AKT3 expression by sponging miR-150-5p in Hirschsprung’s disease

Circular RNA ZNF609 functions as a competitive endogenous RNA to regulate AKT3 expression by sponging miR-150-5p in Hirschsprung’s disease

https://doi.org/10.18632/oncotarget.13656

Lei Peng, Guanglin Chen, Zhongxian Zhu, Ziyang Shen, Chunxia Du, Rujin Zang, Yang Su, Hua Xie, Hongxing Li, Xiaoqun Xu, Yankai Xia,  and Weibing Tang
808-818
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

M2-like tumor-associated macrophages drive vasculogenic mimicry through amplification of IL-6 expression in glioma cells

M2-like tumor-associated macrophages drive vasculogenic mimicry through amplification of IL-6 expression in glioma cells

https://doi.org/10.18632/oncotarget.13661

Lin Zhang, Yangyang Xu, Jintang Sun, Weiliang Chen, Lei Zhao, Chao Ma, Qingjie Wang, Jia Sun, Bin Huang, Yun Zhang, Xingang Li,  and Xun Qu
819-832
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

DYRK1B blocks canonical and promotes non-canonical Hedgehog signaling through activation of the mTOR/AKT pathway

DYRK1B blocks canonical and promotes non-canonical Hedgehog signaling through activation of the mTOR/AKT pathway

https://doi.org/10.18632/oncotarget.13662

Rajeev Singh, Pavan Kumar Dhanyamraju,  and Matthias Lauth
833-845
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mapping heterogeneity in patient-derived melanoma cultures by single-cell RNA-seq

Mapping heterogeneity in patient-derived melanoma cultures by single-cell RNA-seq

https://doi.org/10.18632/oncotarget.13666

Tobias Gerber, Edith Willscher, Henry Loeffler-Wirth, Lydia Hopp, Dirk Schadendorf, Manfred Schartl, Ulf Anderegg, Gray Camp, Barbara Treutlein, Hans Binder,  and Manfred Kunz
846-862
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TRIM28 multi-domain protein regulates cancer stem cell population in breast tumor development

TRIM28 multi-domain protein regulates cancer stem cell population in breast tumor development

https://doi.org/10.18632/oncotarget.13273

Patrycja Czerwińska, Parantu K. Shah, Katarzyna Tomczak, Marta Klimczak, Sylwia Mazurek, Barbara Sozańska, Przemysław Biecek, Konstanty Korskis, Violetta Filas, Andrzej Mackiewicz, Jannik N. Andersen,  and Maciej Wiznerowicz
863-882
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Baicalein reduces angiogenesis in the inflammatory microenvironment via inhibiting the expression of AP-1

Baicalein reduces angiogenesis in the inflammatory microenvironment via inhibiting the expression of AP-1

https://doi.org/10.18632/oncotarget.13669

Yujie Huang, Zhaorui Miao, Yang Hu, Yang Yuan, Yuxin Zhou, Libin Wei, Kai Zhao, Qinglong Guo,  and Na Lu
883-899
Abstract  |  PDF  |  HTML  |  Order a Reprint

Epigenetically upregulated WIPF1 plays a major role in BRAF V600E-promoted papillary thyroid cancer aggressiveness

Epigenetically upregulated WIPF1 plays a major role in BRAF V600E-promoted papillary thyroid cancer aggressiveness

https://doi.org/10.18632/oncotarget.13400

Tao Zhang, Xiaopei Shen, Rengyun Liu, Guangwu Zhu, Justin Bishop,  and Mingzhao Xing
900-914
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Non-toxic dose of liposomal honokiol suppresses metastasis of hepatocellular carcinoma through destabilizing EGFR and inhibiting the downstream pathways

Non-toxic dose of liposomal honokiol suppresses metastasis of hepatocellular carcinoma through destabilizing EGFR and inhibiting the downstream pathways

https://doi.org/10.18632/oncotarget.13687

Jianhong Yang, Heying Pei, Hong Luo, Afu Fu, Hansuo Yang, Jia Hu, Chengjian Zhao, LuLu Chai, Xiang Chen, Ximing Shao, Chunyu Wang, Wenshuang Wu, Li Wan, Haoyu Ye, Qiang Qiu, Aihua Peng, Yuquan Wei, Li Yang,  and Lijuan Chen
915-932
Abstract  |  PDF  |  HTML  |  Order a Reprint

PSMC2 is up-regulated in osteosarcoma and regulates osteosarcoma cell proliferation, apoptosis and migration

PSMC2 is up-regulated in osteosarcoma and regulates osteosarcoma cell proliferation, apoptosis and migration

https://doi.org/10.18632/oncotarget.13511

Mingzhi Song, Yong Wang, Zhen Zhang,  and Shouyu Wang
933-953
Abstract  |  PDF  |  HTML  |  Order a Reprint

Hierarchical investigating the predictive value of p53, COX2, EGFR, nm23 in the post-operative patients with colorectal carcinoma

Hierarchical investigating the predictive value of p53, COX2, EGFR, nm23 in the post-operative patients with colorectal carcinoma

https://doi.org/10.18632/oncotarget.13512

Peng Du, Bin Xu, Dachuan Zhang, Yingjie Shao, Xiao Zheng, Xiaodong Li, Yuqi Xiong, Changping Wu,  and Jingting Jiang
954-966
Abstract  |  PDF  |  HTML  |  Order a Reprint

Unconjugated secondary bile acids activate the unfolded protein response and induce golgi fragmentation via a src-kinase-dependant mechanism

Unconjugated secondary bile acids activate the unfolded protein response and induce golgi fragmentation via a src-kinase-dependant mechanism

https://doi.org/10.18632/oncotarget.13514

Ruchika Sharma, Francis Quilty, John F. Gilmer, Aideen Long,  and Anne-Marie Byrne
967-978
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gremlin promotes retinal pigmentation epithelial (RPE) cell proliferation, migration and VEGF production via activating VEGFR2-Akt-mTORC2 signaling

Gremlin promotes retinal pigmentation epithelial (RPE) cell proliferation, migration and VEGF production via activating VEGFR2-Akt-mTORC2 signaling

https://doi.org/10.18632/oncotarget.13518

Yuan Liu, Zhijun Chen, Haixia Cheng, Juan Chen,  and Jing Qian
979-987
Abstract  |  PDF  |  HTML  |  Order a Reprint

Preclinical study of cinobufagin as a promising anti-colorectal cancer agent

Preclinical study of cinobufagin as a promising anti-colorectal cancer agent

https://doi.org/10.18632/oncotarget.13519

Xing-sheng Lu, Yin-biao Qiao, Ya Li, Bo Yang, Min-bin Chen,  and Chun-gen Xing
988-998
Abstract  |  PDF  |  HTML  |  Order a Reprint

TGFβ1 overexpression is associated with improved survival and low tumor cell proliferation in patients with early-stage pancreatic ductal adenocarcinoma

TGFβ1 overexpression is associated with improved survival and low tumor cell proliferation in patients with early-stage pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.13533

Evan S. Glazer, Eric Welsh, Jose M. Pimiento, Jamie K. Teer,  and Mokenge P. Malafa
999-1006
Abstract  |  PDF  |  HTML  |  Order a Reprint

New use of an old drug: inhibition of breast cancer stem cells by benztropine mesylate

New use of an old drug: inhibition of breast cancer stem cells by benztropine mesylate

https://doi.org/10.18632/oncotarget.13537

Jihong Cui, Maija Hollmén, Lina Li, Yong Chen, Steven T. Proulx, Daniel Reker, Gisbert Schneider,  and Michael Detmar
1007-1022
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Platelet-lymphocyte ratio acts as an indicator of poor prognosis in patients with breast cancer

Platelet-lymphocyte ratio acts as an indicator of poor prognosis in patients with breast cancer

https://doi.org/10.18632/oncotarget.13714

Yanyun Zhu, Wen Si, Qiong Sun, Boyu Qin, Weihong Zhao,  and Junlan Yang
1023-1030
Abstract  |  PDF  |  HTML  |  Order a Reprint

Chemopreventive effects of 5-aminosalicylic acid on inflammatory bowel disease-associated colorectal cancer and dysplasia: a systematic review with meta-analysis

Chemopreventive effects of 5-aminosalicylic acid on inflammatory bowel disease-associated colorectal cancer and dysplasia: a systematic review with meta-analysis

https://doi.org/10.18632/oncotarget.13715

Xinyun Qiu, Jingjing Ma, Kai Wang,  and Hongjie Zhang
1031-1045
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MET expression and copy number status in clear-cell renal cell carcinoma: prognostic value and potential predictive marker

MET expression and copy number status in clear-cell renal cell carcinoma: prognostic value and potential predictive marker

https://doi.org/10.18632/oncotarget.13540

Stephan Macher-Goeppinger, Martina Keith, Volker Endris, Roland Penzel, Katrin E. Tagscherer, Sascha Pahernik, Markus Hohenfellner, Humphrey Gardner, Carsten Grüllich, Peter Schirmacher,  and Wilfried Roth
1046-1057
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mitochondrial pyruvate carrier function is negatively linked to Warburg phenotype in vitro and malignant features in esophageal squamous cell carcinomas

Mitochondrial pyruvate carrier function is negatively linked to Warburg phenotype in vitro and malignant features in esophageal squamous cell carcinomas

https://doi.org/10.18632/oncotarget.13717

Yaqing Li, Xiaoran Li, Quancheng Kan, Mingzhi Zhang, Xiaoli Li, Ruiping Xu, Junsheng Wang, Dandan Yu, Mariusz Adam Goscinski, Jian-Guo Wen, Jahn M. Nesland,  and Zhenhe Suo
1058-1073
Abstract  |  PDF  |  HTML  |  Order a Reprint

DNA methylation signature (SAM40) identifies subgroups of the Luminal A breast cancer samples with distinct survival

DNA methylation signature (SAM40) identifies subgroups of the Luminal A breast cancer samples with distinct survival

https://doi.org/10.18632/oncotarget.13718

Thomas Fleischer, Jovana Klajic, Miriam Ragle Aure, Riku Louhimo, Arne V. Pladsen, Lars Ottestad, Nizar Touleimat, Marko Laakso, Ann Rita Halvorsen, Grethe I. Grenaker Alnæs, Margit L.H. Riis, Åslaug Helland, Sampsa Hautaniemi, Per Eystein Lønning, Bjørn Naume, Anne-Lise Børresen-Dale, Jörg Tost,  and Vessela N. Kristensen
1074-1082
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impact of hematological inflammatory markers on clinical outcome in patients with salivary duct carcinoma: a multi-institutional study in Japan

Impact of hematological inflammatory markers on clinical outcome in patients with salivary duct carcinoma: a multi-institutional study in Japan

https://doi.org/10.18632/oncotarget.13565

Daisuke Kawakita, Yuichiro Tada, Yorihisa Imanishi, Shintaro Beppu, Kiyoaki Tsukahara, Satoshi Kano, Hiroyuki Ozawa, Kenji Okami, Yuichiro Sato, Akira Shimizu, Yukiko Sato, Chihiro Fushimi, Soichiro Takase, Takuro Okada, Hiroki Sato, Kuninori Otsuka, Yoshihiro Watanabe, Akihiro Sakai, Koji Ebisumoto, Takafumi Togashi, Yushi Ueki, Hisayuki Ota, Tomotaka Shimura, Toyoyuki Hanazawa, Shingo Murakami,  and Toshitaka Nagao
1083-1091
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Spermidine/spermine N1-acetyltransferase regulates cell growth and metastasis via AKT/β-catenin signaling pathways in hepatocellular and colorectal carcinoma cells

Spermidine/spermine N1-acetyltransferase regulates cell growth and metastasis via AKT/β-catenin signaling pathways in hepatocellular and colorectal carcinoma cells

https://doi.org/10.18632/oncotarget.13582

Cong Wang, Ping Ruan, Ying Zhao, Xiaomin Li, Jun Wang, Xiaoxiao Wu, Tong Liu, Shasha Wang, Jiuzhou Hou, Wei Li, Qian Li, Jinghua Li, Fujun Dai, Dong Fang, Chaojie Wang,  and Songqiang Xie
1092-1109
Abstract  |  PDF  |  HTML  |  Order a Reprint

The change of HCN1/HCN2 mRNA expression in peripheral nerve after chronic constriction injury induced neuropathy followed by pulsed electromagnetic field therapy

The change of HCN1/HCN2 mRNA expression in peripheral nerve after chronic constriction injury induced neuropathy followed by pulsed electromagnetic field therapy

https://doi.org/10.18632/oncotarget.13584

Hui Liu, Jun Zhou, Lianbing Gu,  and Yunxia Zuo
1110-1116
Abstract  |  PDF  |  HTML  |  Order a Reprint

The neurotrophin Neuritin1 (cpg15) is involved in melanoma migration, attachment independent growth, and vascular mimicry

The neurotrophin Neuritin1 (cpg15) is involved in melanoma migration, attachment independent growth, and vascular mimicry

https://doi.org/10.18632/oncotarget.13585

Anja Katrin Bosserhoff, Nadja Schneider, Lisa Ellmann, Lucie Heinzerling,  and Silke Kuphal
1117-1131
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Molecular mechanism of hepatitis B virus (HBV) on suppression of raf kinase inhibitor protein (RKIP) expression

Molecular mechanism of hepatitis B virus (HBV) on suppression of raf kinase inhibitor protein (RKIP) expression

https://doi.org/10.18632/oncotarget.13586

Xiao-Ke Cheng, Guo-Zheng Yu, Xiao-Dong Li,  and Xue-Qun Ren
1132-1140
Abstract  |  PDF  |  HTML  |  Order a Reprint

Efficacy and safety of angiogenesis inhibitors in small-cell lung cancer

Efficacy and safety of angiogenesis inhibitors in small-cell lung cancer

https://doi.org/10.18632/oncotarget.13588

Heng Lin, Lina Li, Shuimei Luo, Sijing Zhou, Ruifen Shen, Haitao Yang, Huijuan Chen,  and Xianhe Xie
1141-1155
Abstract  |  PDF  |  HTML  |  Order a Reprint

The association between the TP53 Arg72Pro polymorphism and colorectal cancer: An updated meta-analysis based on 32 studies

The association between the TP53 Arg72Pro polymorphism and colorectal cancer: An updated meta-analysis based on 32 studies

https://doi.org/10.18632/oncotarget.13589

Xin Tian, Shundong Dai, Jing Sun, Shenyi Jiang,  and Youhong Jiang
1156-1165
Abstract  |  PDF  |  HTML  |  Order a Reprint

TIMP-2 SNPs rs7342880 and rs4789936 are linked to risk of knee osteoarthritis in the Chinese Han Population

TIMP-2 SNPs rs7342880 and rs4789936 are linked to risk of knee osteoarthritis in the Chinese Han Population

https://doi.org/10.18632/oncotarget.13590

Pengcheng Xu, Wen Guo, Tianbo Jin, Jihong Wang, Dongsheng Fan, Zengtao Hao, Shangfei Jing, ChaoQian Han, Jieli Du, Dong Jiang, Shuzheng Wen,  and Jianzhong Wang
1166-1176
Abstract  |  PDF  |  HTML  |  Order a Reprint

Human pancreatic cancer xenografts recapitulate key aspects of cancer cachexia

Human pancreatic cancer xenografts recapitulate key aspects of cancer cachexia

https://doi.org/10.18632/oncotarget.13593

Daniel Delitto, Sarah M. Judge, Andrea E. Delitto, Rachel L. Nosacka, Fernanda G. Rocha, Bayli B. DiVita, Michael H. Gerber, Thomas J. George Jr, Kevin E. Behrns, Steven J. Hughes, Shannon M. Wallet, Andrew R. Judge,  and Jose G. Trevino
1177-1189
Abstract  |  PDF  |  HTML  |  Order a Reprint

Hyperglycemia triggers HIPK2 protein degradation

Hyperglycemia triggers HIPK2 protein degradation

https://doi.org/10.18632/oncotarget.13595

Silvia Baldari, Alessia Garufi, Marisa Granato, Laura Cuomo, Giuseppa Pistritto, Mara Cirone,  and Gabriella D’Orazi
1190-1203
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Meta-analysis on the association of VEGFR1 genetic variants with sunitinib outcome in metastatic renal cell carcinoma patients

Meta-analysis on the association of VEGFR1 genetic variants with sunitinib outcome in metastatic renal cell carcinoma patients

https://doi.org/10.18632/oncotarget.13597

Xiaoyan Liu, Jesse J. Swen, Epie Boven, Daniel Castellano, Hans Gelderblom, Ron H.J. Mathijssen, Cristina Rodríguez-Antona, Jesus García-Donas, Brian I. Rini,  and Henk-Jan Guchelaar
1204-1212
Abstract  |  PDF  |  HTML  |  Order a Reprint

Gene expression profiling of hematologic malignant cell lines resistant to oncolytic virus treatment

Gene expression profiling of hematologic malignant cell lines resistant to oncolytic virus treatment

https://doi.org/10.18632/oncotarget.13598

Nam Hee Lee, Mikyung Kim, Sung Yong Oh, Seong-Geun Kim, Hyuk-Chan Kwon,  and Tae-Ho Hwang
1213-1225
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-146a rs2910164 polymorphism and head and neck carcinoma risk: a meta-analysis based on 10 case-control studies

MiR-146a rs2910164 polymorphism and head and neck carcinoma risk: a meta-analysis based on 10 case-control studies

https://doi.org/10.18632/oncotarget.13599

Zhaolan Xiang, Jue Song, Xianlu Zhuo, Qi Li,  and Xueyuan Zhang
1226-1233
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of a novel Polo-like kinase 1 inhibitor that specifically blocks the functions of Polo-Box domain

Identification of a novel Polo-like kinase 1 inhibitor that specifically blocks the functions of Polo-Box domain

https://doi.org/10.18632/oncotarget.13603

Yunyu Chen, Jing Zhang, Dongsheng Li, Jiandong Jiang, Yanchang Wang,  and Shuyi Si
1234-1246
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HOXB7 overexpression promotes cell proliferation and correlates with poor prognosis in gastric cancer patients by inducing expression of both AKT and MARKs

HOXB7 overexpression promotes cell proliferation and correlates with poor prognosis in gastric cancer patients by inducing expression of both AKT and MARKs

https://doi.org/10.18632/oncotarget.13604

Xujun He, Zhengchuang Liu, Yingjie Xia, Ji Xu, Guocai Lv, Lu Wang, Tonghui Ma, Liping Jiang, Yiping Mou, Xiaoting Jiang, Jie Ma, Zhongkuo Zhao, Haibin Ni, Wenjuan Xu, Guoqing Ru, Dongsheng Huang,  and Houquan Tao
1247-1261
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Down regulation of RNA binding motif, single-stranded interacting protein 3, along with up regulation of nuclear HIF1A correlates with poor prognosis in patients with gastric cancer

Down regulation of RNA binding motif, single-stranded interacting protein 3, along with up regulation of nuclear HIF1A correlates with poor prognosis in patients with gastric cancer

https://doi.org/10.18632/oncotarget.13605

Youliang Wu, Dapeng Yun, Yingjie Zhao, Yuqi Wang, Ruochuan Sun, Qiang Yan, Shangxin Zhang, Mingdian Lu, Zhen Zhang, Daru Lu,  and Yongxiang Li
1262-1277
Abstract  |  PDF  |  HTML  |  Order a Reprint

Association of smoking status with prognosis in bladder cancer: A meta-analysis

Association of smoking status with prognosis in bladder cancer: A meta-analysis

https://doi.org/10.18632/oncotarget.13606

Lina Hou, Xuwei Hong, Meng Dai, Pengliang Chen, Hongfan Zhao, Qiang Wei, Fei Li,  and Wanlong Tan
1278-1289
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cancer-associated fibroblasts promote cancer cell growth through a miR-7-RASSF2-PAR-4 axis in the tumor microenvironment

Cancer-associated fibroblasts promote cancer cell growth through a miR-7-RASSF2-PAR-4 axis in the tumor microenvironment

https://doi.org/10.18632/oncotarget.13609

Zongze Shen, Xing Qin, Ming Yan, Rongrong Li, Gang Chen, Jianjun Zhang,  and Wantao Chen
1290-1303
Abstract  |  PDF  |  HTML  |  Order a Reprint

Membrane-bound ICAM-1 contributes to the onset of proinvasive tumor stroma by controlling acto-myosin contractility in carcinoma-associated fibroblasts

Membrane-bound ICAM-1 contributes to the onset of proinvasive tumor stroma by controlling acto-myosin contractility in carcinoma-associated fibroblasts

https://doi.org/10.18632/oncotarget.13610

Stephanie Bonan, Jean Albrengues, Eloise Grasset, Sanya-Eduarda Kuzet, Nicolas Nottet, Isabelle Bourget, Thomas Bertero, Bernard Mari, Guerrino Meneguzzi,  and Cedric Gaggioli
1304-1320
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genomic and transcriptomic characterization of skull base chordoma

Genomic and transcriptomic characterization of skull base chordoma

https://doi.org/10.18632/oncotarget.13616

Jason K. Sa, In-Hee Lee, Sang Duk Hong, Doo-Sik Kong,  and Do-Hyun Nam
1321-1328
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Has aidi injection the attenuation and synergistic efficacy to gemcitabine and cisplatin in non-small cell lung cancer? A meta-analysis of 36 randomized controlled trials

Has aidi injection the attenuation and synergistic efficacy to gemcitabine and cisplatin in non-small cell lung cancer? A meta-analysis of 36 randomized controlled trials

https://doi.org/10.18632/oncotarget.13617

Zheng Xiao, Chengqiong Wang, Ling Chen, Xuemei Tang, Lianhong Li, Nana Li, Jing Li, Qihai Gong, Fushan Tang, Jihong Feng,  and Xiaofei Li
1329-1342
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Analysis of progression-free survival of first-line tyrosine kinase inhibitors in patients with non-small cell lung cancer harboring leu858Arg or exon 19 deletions

Analysis of progression-free survival of first-line tyrosine kinase inhibitors in patients with non-small cell lung cancer harboring leu858Arg or exon 19 deletions

https://doi.org/10.18632/oncotarget.13815

Feng-Che Kuan, Shih-Hong Li, Chih-Liang Wang, Meng-Hung Lin, Ying-Huang Tsai,  and Cheng-Ta Yang
1343-1353
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The involvement of Bcl-2 family proteins in AKT-regulated cell survival in cisplatin resistant epithelial ovarian cancer

The involvement of Bcl-2 family proteins in AKT-regulated cell survival in cisplatin resistant epithelial ovarian cancer

https://doi.org/10.18632/oncotarget.13817

Yan Dai, Shiguang Jin, Xueping Li,  and Daxin Wang
1354-1368
Abstract  |  PDF  |  HTML  |  Order a Reprint

Air pollution and DNA methylation alterations in lung cancer: A systematic and comparative study

Air pollution and DNA methylation alterations in lung cancer: A systematic and comparative study

https://doi.org/10.18632/oncotarget.13622

Cheng-Lan Jiang, Shui-Wang He, Yun-Dong Zhang, He-Xian Duan, Tao Huang, Yun-Chao Huang, Gao-Feng Li, Ping Wang, Li-Ju Ma, Guang-Biao Zhou,  and Yi Cao
1369-1391
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cancer initiating-cells are enriched in the CA9 positive fraction of primary cervix cancer xenografts

Cancer initiating-cells are enriched in the CA9 positive fraction of primary cervix cancer xenografts

https://doi.org/10.18632/oncotarget.13625

Delphine Tamara Marie-Egyptienne, Naz Chaudary, Tuula Kalliomäki, David William Hedley,  and Richard Peter Hill
1392-1404
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TFDP3 confers chemoresistance in minimal residual disease within childhood T-cell acute lymphoblastic leukemia

TFDP3 confers chemoresistance in minimal residual disease within childhood T-cell acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.13630

Ming Chu, Kailin Yin, Yujun Dong, Pingzhang Wang, Yun Xue, Peng Zhou, Yuqi Wang,  and Yuedan Wang
1405-1415
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

DNA sequences within glioma-derived extracellular vesicles can cross the intact blood-brain barrier and be detected in peripheral blood of patients

DNA sequences within glioma-derived extracellular vesicles can cross the intact blood-brain barrier and be detected in peripheral blood of patients

https://doi.org/10.18632/oncotarget.13635

Noemí García-Romero, Josefa Carrión-Navarro, Susana Esteban-Rubio, Elisa Lázaro-Ibáñez, María Peris-Celda, Marta M. Alonso, Juan Guzmán-De-Villoria, Carlos Fernández-Carballal, Ana Ortiz de Mendivil, Sara García-Duque, Carmen Escobedo-Lucea, Ricardo Prat-Acín, Cristóbal Belda-Iniesta,  and Angel Ayuso-Sacido
1416-1428
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LncRNA H19 inhibits autophagy by epigenetically silencing of DIRAS3 in diabetic cardiomyopathy

LncRNA H19 inhibits autophagy by epigenetically silencing of DIRAS3 in diabetic cardiomyopathy

https://doi.org/10.18632/oncotarget.13637

Chuanjun Zhuo, Ronghuan Jiang, Xiaodong Lin,  and Mingjing Shao
1429-1437
Abstract  |  PDF  |  HTML  |  Order a Reprint

Tumor-associated mesenchymal stem-like cells provide extracellular signaling cue for invasiveness of glioblastoma cells

Tumor-associated mesenchymal stem-like cells provide extracellular signaling cue for invasiveness of glioblastoma cells

https://doi.org/10.18632/oncotarget.13638

Eun-Jung Lim, Yongjoon Suh, Ki-Chun Yoo, Ji-Hyun Lee, In-Gyu Kim, Min-Jung Kim, Jong Hee Chang, Seok-Gu Kang,  and Su-Jae Lee
1438-1448
Abstract  |  PDF  |  HTML  |  Order a Reprint

PDE5 inhibitors enhance the lethality of pemetrexed through inhibition of multiple chaperone proteins and via the actions of cyclic GMP and nitric oxide

PDE5 inhibitors enhance the lethality of pemetrexed through inhibition of multiple chaperone proteins and via the actions of cyclic GMP and nitric oxide

https://doi.org/10.18632/oncotarget.13640

Laurence Booth, Jane L. Roberts, Andrew Poklepovic, Sarah Gordon,  and Paul Dent
1449-1468
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Novel Src/Abl tyrosine kinase inhibitor bosutinib suppresses neuroblastoma growth via inhibiting Src/Abl signaling

Novel Src/Abl tyrosine kinase inhibitor bosutinib suppresses neuroblastoma growth via inhibiting Src/Abl signaling

https://doi.org/10.18632/oncotarget.13643

Shayahati Bieerkehazhi, Zhenghu Chen, Yanling Zhao, Yang Yu, Huiyuan Zhang, Sanjeev A. Vasudevan, Sarah E. Woodfield, Ling Tao, Joanna S. Yi, Jodi A. Muscal, Jonathan C. Pang, Shan Guan, Hong Zhang, Jed G. Nuchtern, Hui Li, Huiwu Li,  and Jianhua Yang
1469-1480
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeting tissue factor as a novel therapeutic oncotarget for eradication of cancer stem cells isolated from tumor cell lines, tumor xenografts and patients of breast, lung and ovarian cancer

Targeting tissue factor as a novel therapeutic oncotarget for eradication of cancer stem cells isolated from tumor cell lines, tumor xenografts and patients of breast, lung and ovarian cancer

https://doi.org/10.18632/oncotarget.13644

Zhiwei Hu, Jie Xu, Jijun Cheng, Elizabeth McMichael, Lianbo Yu,  and William E. Carson III
1481-1494
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Whole exome sequencing in 75 high-risk families with validation and replication in independent case-control studies identifies TANGO2, OR5H14, and CHAD as new prostate cancer susceptibility genes

Whole exome sequencing in 75 high-risk families with validation and replication in independent case-control studies identifies TANGO2, OR5H14, and CHAD as new prostate cancer susceptibility genes

https://doi.org/10.18632/oncotarget.13646

Danielle M. Karyadi, Milan S. Geybels, Eric Karlins, Brennan Decker, Laura McIntosh, Amy Hutchinson, Suzanne Kolb, Shannon K. McDonnell, Belynda Hicks, Sumit Middha, Liesel M. FitzGerald, Melissa S. DeRycke, Meredith Yeager, Daniel J. Schaid, Stephen J. Chanock, Stephen N. Thibodeau, Sonja I. Berndt, Janet L. Stanford,  and Elaine A. Ostrander
1495-1507
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GDF15 contributes to radioresistance and cancer stemness of head and neck cancer by regulating cellular reactive oxygen species via a SMAD-associated signaling pathway

GDF15 contributes to radioresistance and cancer stemness of head and neck cancer by regulating cellular reactive oxygen species via a SMAD-associated signaling pathway

https://doi.org/10.18632/oncotarget.13649

Yan-Liang Li, Joseph T. Chang, Li-Yu Lee, Kang-Hsing Kang-Hsing Fan, Ya-Ching Lu, Yi-Chen Li, Chang-Hsu Chiang, Guo-Rung You, Hsin-Ying Chen,  and Ann-Joy Cheng
1508-1528
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association of a cytarabine chemosensitivity related gene expression signature with survival in cytogenetically normal acute myeloid leukemia

Association of a cytarabine chemosensitivity related gene expression signature with survival in cytogenetically normal acute myeloid leukemia

https://doi.org/10.18632/oncotarget.13650

Han Yan, Lu Wen, Dan Tan, Pan Xie, Feng-mei Pang, Hong-hao Zhou, Wei Zhang, Zhao-qian Liu, Jie Tang, Xi Li,  and Xiao-ping Chen
1529-1540
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cortactin promotes colorectal cancer cell proliferation by activating the EGFR-MAPK pathway

Cortactin promotes colorectal cancer cell proliferation by activating the EGFR-MAPK pathway

https://doi.org/10.18632/oncotarget.13652

Xiaojian Zhang, Kun Liu, Tao Zhang, Zhenlei Wang, Xuan Qin, Xiaoqian Jing, Haoxuan Wu, Xiaopin Ji, Yonggang He,  and Ren Zhao
1541-1554
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Novel multi-targeted ErbB family inhibitor afatinib blocks EGF-induced signaling and induces apoptosis in neuroblastoma

Novel multi-targeted ErbB family inhibitor afatinib blocks EGF-induced signaling and induces apoptosis in neuroblastoma

https://doi.org/10.18632/oncotarget.13657

Xinfang Mao, Zhenghu Chen, Yanling Zhao, Yang Yu, Shan Guan, Sarah E. Woodfield, Sanjeev A. Vasudevan, Ling Tao, Jonathan C. Pang, Jiaxiong Lu, Huiyuan Zhang, Fuchun Zhang,  and Jianhua Yang
1555-1568
Abstract  |  PDF  |  HTML  |  Order a Reprint

Hemoglobin level trajectories in the early treatment period are related with survival outcomes in patients with breast cancer

Hemoglobin level trajectories in the early treatment period are related with survival outcomes in patients with breast cancer

https://doi.org/10.18632/oncotarget.13679

Chia-Lin Lee, Chun-Hao Tsai, Dah-Cherng Yeh, Chi-Shy Lin, Yu-Fen Li,  and Huey-En Tzeng
1569-1579
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Risk stratification of thyroid nodules with Bethesda category III results on fine-needle aspiration cytology: The additional value of acoustic radiation force impulse elastography

Risk stratification of thyroid nodules with Bethesda category III results on fine-needle aspiration cytology: The additional value of acoustic radiation force impulse elastography

https://doi.org/10.18632/oncotarget.13685

Chong-Ke Zhao, Hui-Xiong Xu, Jun-Mei Xu, Cheng-Yu Sun, Wei Chen, Bo-Ji Liu, Xiao-Wan Bo, Dan Wang,  and Shen Qu
1580-1592
Abstract  |  PDF  |  HTML  |  Order a Reprint

Stag3 regulates microtubule stability to maintain euploidy during mouse oocyte meiotic maturation

Stag3 regulates microtubule stability to maintain euploidy during mouse oocyte meiotic maturation

https://doi.org/10.18632/oncotarget.13684

Mianqun Zhang, Xiaoxin Dai, Yalu Sun, Yajuan Lu, Changyin Zhou, Yilong Miao, Ying Wang,  and Bo Xiong
1593-1602
Abstract  |  PDF  |  HTML  |  Order a Reprint

Multiplex ligation-dependent probe amplification assay identifies additional copy number changes compared with R-band karyotype and provide more accuracy prognostic information in myelodysplastic syndromes

Multiplex ligation-dependent probe amplification assay identifies additional copy number changes compared with R-band karyotype and provide more accuracy prognostic information in myelodysplastic syndromes

https://doi.org/10.18632/oncotarget.13688

Jingya Wang, Xiaofei Ai, Tiejun Qin, Zefeng Xu, Yue Zhang, Jinqin Liu, Bing Li, Liwei Fang, Hongli Zhang, Lijuan Pan, Naibo Hu, Shiqiang Qu, Wenyu Cai, Kun Ru, Yujiao Jia, Gang Huang,  and Zhijian Xiao
1603-1612
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nuclear localization of the CK2α-subunit correlates with poor prognosis in clear cell renal cell carcinoma

Nuclear localization of the CK2α-subunit correlates with poor prognosis in clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.13693

Maj Rabjerg, Barbara Guerra, Aida Oliván-Viguera, Minne Line Nedergaard Mikkelsen, Ralf Köhler, Olaf-Georg Issinger,  and Niels Marcussen
1613-1627
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pyruvate kinase M2 (PKM2) expression correlates with prognosis in solid cancers: a meta-analysis

Pyruvate kinase M2 (PKM2) expression correlates with prognosis in solid cancers: a meta-analysis

https://doi.org/10.18632/oncotarget.13703

Haiyan Zhu, Hui Luo, Xuejie Zhu, Xiaoli Hu, Lihong Zheng,  and Xueqiong Zhu
1628-1640
Abstract  |  PDF  |  HTML  |  Order a Reprint

The metastasis suppressor CD82/KAI1 inhibits fibronectin adhesion-induced epithelial-to-mesenchymal transition in prostate cancer cells by repressing the associated integrin signaling

The metastasis suppressor CD82/KAI1 inhibits fibronectin adhesion-induced epithelial-to-mesenchymal transition in prostate cancer cells by repressing the associated integrin signaling

https://doi.org/10.18632/oncotarget.13767

Jaeseob Lee, Hee-Jung Byun, Moon-Sung Lee, Young-June Jin, Dooil Jeoung, Young-Myeong Kim,  and Hansoo Lee
1641-1654
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High lncRNA H19 expression as prognostic indicator: data mining in female cancers and polling analysis in non-female cancers

High lncRNA H19 expression as prognostic indicator: data mining in female cancers and polling analysis in non-female cancers

https://doi.org/10.18632/oncotarget.13768

Li Peng, Xiao-Qing Yuan, Zhao-Yang Liu, Wen-Ling Li, Chao-Yang Zhang, Ya-Qin Zhang, Xi Pan, Jun Chen, Yue-Hui Li,  and Guan-Cheng Li
1655-1667
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Suppression of immune regulatory cells with combined therapy of celecoxib and sunitinib in renal cell carcinoma

Suppression of immune regulatory cells with combined therapy of celecoxib and sunitinib in renal cell carcinoma

https://doi.org/10.18632/oncotarget.13774

Qi Zhao, Jianming Guo, Guomin Wang, Yiwei Chu,  and Xiaoyi Hu
1668-1677
Abstract  |  PDF  |  HTML  |  Order a Reprint

p38 and JNK pathways control E-selectin-dependent extravasation of colon cancer cells by modulating miR-31 transcription

p38 and JNK pathways control E-selectin-dependent extravasation of colon cancer cells by modulating miR-31 transcription

https://doi.org/10.18632/oncotarget.13779

Liang Zhong, Bryan Simoneau, Jacques Huot,  and Martin J. Simard
1678-1687
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The cross-talk between autophagy and endoplasmic reticulum stress in blood-spinal cord barrier disruption after spinal cord injury

The cross-talk between autophagy and endoplasmic reticulum stress in blood-spinal cord barrier disruption after spinal cord injury

https://doi.org/10.18632/oncotarget.13777

Yulong Zhou, Yanqing Wu, Yanlong Liu, Zili He, Shuang Zou, Qingqing Wang, Jiawei Li, Zengming Zheng, Jian Chen, Fenzan Wu, Fanhua Gong, Hongyu Zhang, Huazi Xu,  and Jian Xiao
1688-1702
Abstract  |  PDF  |  HTML  |  Order a Reprint

FOXO1 inhibits the invasion and metastasis of hepatocellular carcinoma by reversing ZEB2-induced epithelial-mesenchymal transition

FOXO1 inhibits the invasion and metastasis of hepatocellular carcinoma by reversing ZEB2-induced epithelial-mesenchymal transition

https://doi.org/10.18632/oncotarget.13786

Tianxiu Dong, Yu Zhang, Yaodong Chen, Pengfei Liu, Tingting An, Jiuwei Zhang, Haichao Yang, Wenjing Zhu,  and Xiuhua Yang
1703-1713
Abstract  |  PDF  |  HTML  |  Order a Reprint

NEDD9 may regulate hepatocellular carcinoma cell metastasis by promoting epithelial-mesenchymal-transition and stemness via repressing Smad7

NEDD9 may regulate hepatocellular carcinoma cell metastasis by promoting epithelial-mesenchymal-transition and stemness via repressing Smad7

https://doi.org/10.18632/oncotarget.13852

Zhipeng Wang, Min Shen, Peng Lu, Xiao Li, Shaojun Zhu,  and Shuqiang Yue
1714-1724
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Induction of hypoxia and necrosis in multicellular tumor spheroids is associated with resistance to chemotherapy treatment

Induction of hypoxia and necrosis in multicellular tumor spheroids is associated with resistance to chemotherapy treatment

https://doi.org/10.18632/oncotarget.13857

Silvio Däster, Nunzia Amatruda, Diego Calabrese, Robert Ivanek, Eleonora Turrini, Raoul A. Droeser, Paul Zajac, Carmela Fimognari, Giulio C. Spagnoli, Giandomenica Iezzi, Valentina Mele,  and Manuele G. Muraro
1725-1736
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value of whole-body SUVmax of nodal and extra-nodal lesions detected by 18F-FDG PET/CT in extra-nodal NK/T-cell lymphoma

Prognostic value of whole-body SUVmax of nodal and extra-nodal lesions detected by 18F-FDG PET/CT in extra-nodal NK/T-cell lymphoma

https://doi.org/10.18632/oncotarget.13873

Jin-Hua Liang, Chong-Yang Ding, Robert Peter Gale, Li Wang, Ji Xu, Xiao-Yan Qu, Lei Fan, Tian-Lv Li, Jian-Yong Li,  and Wei Xu
1737-1743
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Differentiation of pancreatic carcinoma and mass-forming focal pancreatitis: qualitative and quantitative assessment by dynamic contrast-enhanced MRI combined with diffusion-weighted imaging

Differentiation of pancreatic carcinoma and mass-forming focal pancreatitis: qualitative and quantitative assessment by dynamic contrast-enhanced MRI combined with diffusion-weighted imaging

https://doi.org/10.18632/oncotarget.12120

Ting-Ting Zhang, Li Wang, Huan-huan Liu, Cai-yuan Zhang, Xiao-ming Li, Jian-ping Lu,  and Deng-bin Wang
1744-1759
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic factors of successful on-purpose tumor biopsies in metastatic cancer patients included in the SHIVA prospective clinical trial

Prognostic factors of successful on-purpose tumor biopsies in metastatic cancer patients included in the SHIVA prospective clinical trial

https://doi.org/10.18632/oncotarget.12051

Emilie Desportes, Mathilde Wagner, Maud Kamal, Anne Vincent Salomon, Gabrielle Deniziaut, Gaëlle Pierron, Etienne Rouleau, Thomas Jouffroy, Christophe Le Tourneau, Xavier Paoletti,  and Vincent Servois
1760-1773
Abstract  |  PDF  |  HTML  |  Order a Reprint

Metavir and FIB-4 scores are associated with patient prognosis after curative hepatectomy in hepatitis B virus-related hepatocellular carcinoma: a retrospective cohort study at two centers in China

Metavir and FIB-4 scores are associated with patient prognosis after curative hepatectomy in hepatitis B virus-related hepatocellular carcinoma: a retrospective cohort study at two centers in China

https://doi.org/10.18632/oncotarget.12152

Rui Liao, Yi-Peng Fu, Ting Wang, Zhi-Gang Deng, De-Wei Li, Jia Fan, Jian Zhou, Gen-Sheng Feng, Shuang-Jian Qiu,  and Cheng-You Du
1774-1787
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Necessity of organized low-dose computed tomography screening for lung cancer: From epidemiologic comparisons between China and the Western nations

Necessity of organized low-dose computed tomography screening for lung cancer: From epidemiologic comparisons between China and the Western nations

https://doi.org/10.18632/oncotarget.12400

Hong-Feng Gou, Yang Liu, Tian-Xia Yang, Cheng Zhou,  and Xin-Zu Chen
1788-1795
Abstract  |  PDF  |  HTML  |  Order a Reprint

Optimal radiation dose for patients with one to three lymph node positive breast cancer following breast-conserving surgery and anthracycline plus taxane-based chemotherapy: A retrospective multicenter analysis (KROG 1418)

Optimal radiation dose for patients with one to three lymph node positive breast cancer following breast-conserving surgery and anthracycline plus taxane-based chemotherapy: A retrospective multicenter analysis (KROG 1418)

https://doi.org/10.18632/oncotarget.12882

Haeyoung Kim, Won Park, Jeong Il Yu, Doo Ho Choi, Seung Jae Huh, Yeon-Joo Kim, Eun Sook Lee, Keun Seok Lee, Han-Sung Kang, In Hae Park, Kyung Hwan Shin, Kyubo Kim, Kyung Ran Park, Yong Bae Kim, Sung Ja Ahn, Jong Hoon Lee, Jin Hee Kim, Mison Chun, Hyung-Sik Lee, Jung Soo Kim,  and Jong-Young Lee
1796-1804
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reviews

Liver regeneration microenvironment of hepatocellular carcinoma for prevention and therapy

Liver regeneration microenvironment of hepatocellular carcinoma for prevention and therapy

https://doi.org/10.18632/oncotarget.12101

Hanmin Li,  and Lisheng Zhang
1805-1813
Abstract  |  PDF  |  HTML  |  Order a Reprint

Type I insulin-like growth factor receptor signaling in hematological malignancies

Type I insulin-like growth factor receptor signaling in hematological malignancies

https://doi.org/10.18632/oncotarget.12123

Deeksha Vishwamitra, Suraj Konnath George, Ping Shi, Ahmed O. Kaseb,  and Hesham M. Amin
1814-1844
Abstract  |  PDF  |  HTML  |  Order a Reprint

Sirtuins in glucose and lipid metabolism

Sirtuins in glucose and lipid metabolism

https://doi.org/10.18632/oncotarget.12157

Xin Ye, Meiting Li, Tianyun Hou, Tian Gao, Wei-guo Zhu,  and Yang Yang
1845-1859
Abstract  |  PDF  |  HTML  |  Order a Reprint

Outcomes in adult critically Ill cancer patients with and without neutropenia: a systematic review and meta-analysis of the Groupe de Recherche en Réanimation Respiratoire du patient d’Onco-Hématologie (GRRR-OH)

Outcomes in adult critically Ill cancer patients with and without neutropenia: a systematic review and meta-analysis of the Groupe de Recherche en Réanimation Respiratoire du patient d’Onco-Hématologie (GRRR-OH)

https://doi.org/10.18632/oncotarget.12165

Marie Bouteloup, Sophie Perinel, Aurélie Bourmaud, Elie Azoulay, Djamel Mokart,  and Michael Darmon
1860-1870
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Associations of P16INK4a promoter hypermethylation with squamous intra-epithelial lesion, cervical cancer and their clinicopathological features: a meta-analysis

Associations of P16INK4a promoter hypermethylation with squamous intra-epithelial lesion, cervical cancer and their clinicopathological features: a meta-analysis

https://doi.org/10.18632/oncotarget.12202

Ya-di Han, Xue-bin Wang, Ning-hua Cui, Shuai Zhang, Chen Wang,  and Fang Zheng
1871-1883
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circulating and disseminated tumor cells: diagnostic tools and therapeutic targets in motion

Circulating and disseminated tumor cells: diagnostic tools and therapeutic targets in motion

https://doi.org/10.18632/oncotarget.12242

Hongxia Wang, Nikolas H. Stoecklein, Peter P. Lin,  and Olivier Gires
1884-1912
Abstract  |  PDF  |  HTML  |  Order a Reprint

Triple-negative breast cancer: is there a treatment on the horizon?

Triple-negative breast cancer: is there a treatment on the horizon?

https://doi.org/10.18632/oncotarget.12284

Hui Yao, Guangchun He, Shichao Yan, Chao Chen, Liujiang Song, Thomas J. Rosol,  and Xiyun Deng
1913-1924
Abstract  |  PDF  |  HTML  |  Order a Reprint

Long non-coding RNAs in anti-cancer drug resistance

Long non-coding RNAs in anti-cancer drug resistance

https://doi.org/10.18632/oncotarget.12461

Qin-nan Chen, Chen-chen Wei, Zhao-xia Wang,  and Ming Sun
1925-1936
Abstract  |  PDF  |  HTML  |  Order a Reprint

Role of long noncoding RNA UCA1 as a common molecular marker for lymph node metastasis and prognosis in various cancers: a meta-analysis

Role of long noncoding RNA UCA1 as a common molecular marker for lymph node metastasis and prognosis in various cancers: a meta-analysis

https://doi.org/10.18632/oncotarget.12463

Anbang He, Rong Hu, Zhicong Chen, Xinhui Liao, Jianfa Li, Dailian Wang, Zhaojie Lv, Yuchen Liu, Feng Wang,  and Hongbing Mei
1937-1943
Abstract  |  PDF  |  HTML  |  Order a Reprint

Decreased 5-hydroxymethylcytosine levels correlate with cancer progression and poor survival: a systematic review and meta-analysis

Decreased 5-hydroxymethylcytosine levels correlate with cancer progression and poor survival: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.13719

Zhaoli Chen, Xuejiao Shi, Lanwei Guo, Yuan Li, Mei Luo,  and Jie He
1944-1952
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Corrections

Correction: Renal cell carcinoma alters endothelial receptor expression responsible for leukocyte adhesion

Correction: Renal cell carcinoma alters endothelial receptor expression responsible for leukocyte adhesion

https://doi.org/10.18632/oncotarget.14438

Eva Juengel, Geraldine Krueger, Jochen Rutz, Karen Nelson, Isabella Werner, Borna Relja, Barbara Seliger, Beate Fisslthaler, Ingrid Fleming, Igor Tsaur, Axel Haferkamp,  and Roman A. Blaheta
1953-1954
Correction  |  PDF


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