Oncotarget

Vol 7, No 51

December 20, 2016

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About The Cover

The cover for issue 51 of Oncotarget features Figure 6, 'LCL521 treatment disrupts autophagy to activate lysosomal degradation of stressed ER,' from Liu, et al.

Table of Contents

Editorial

Astrocyte-to-neuron conversion induced by spinal cord injury

Astrocyte-to-neuron conversion induced by spinal cord injury

https://doi.org/10.18632/oncotarget.13780

Harun Najib Noristani,  and Florence Evelyne Perrin
83831-83832
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Editorial: Autophagy and Cell Death

p62 at the crossroad of the ubiquitin-proteasome system and autophagy

p62 at the crossroad of the ubiquitin-proteasome system and autophagy

https://doi.org/10.18632/oncotarget.13805

Victoria Cohen-Kaplan, Aaron Ciechanover,  and Ido Livneh
83833-83834
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Editorial: Neuroscience

Aging of hippocampal neurogenesis and soy isoflavone

Aging of hippocampal neurogenesis and soy isoflavone

https://doi.org/10.18632/oncotarget.13534

Jun Yamada,  and Shozo Jinno
83835-83836
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Research Papers: Pathology

Variable patterns of ectopic mineralization in Enpp1asj-2J mice, a model for generalized arterial calcification of infancy

Variable patterns of ectopic mineralization in Enpp1asj-2J mice, a model for generalized arterial calcification of infancy

https://doi.org/10.18632/oncotarget.13335

Sarah Y. Siu, Nathaniel A. Dyment, David W. Rowe, John P. Sundberg, Jouni Uitto,  and Qiaoli Li
83837-83842
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Targeted next generation sequencing identifies two novel mutations in SEPN1 in rigid spine muscular dystrophy 1

Targeted next generation sequencing identifies two novel mutations in SEPN1 in rigid spine muscular dystrophy 1

https://doi.org/10.18632/oncotarget.13337

Yi Dai, Shengran Liang, Yan Huang, Lin Chen,  and Santasree Banerjee
83843-83849
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Probucol prevents atrial ion channel remodeling in an alloxan-induced diabetes rabbit model

Probucol prevents atrial ion channel remodeling in an alloxan-induced diabetes rabbit model

https://doi.org/10.18632/oncotarget.13339

Huaying Fu, Guangping Li, Changle Liu, Jian Li, Lijun Cheng, Wansong Yang, Gary Tse, Jichao Zhao,  and Tong Liu
83850-83858
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P120 regulates beta-catenin nuclear translocation through E-cadherin endocytosis in ventilator-induced lung injury

P120 regulates beta-catenin nuclear translocation through E-cadherin endocytosis in ventilator-induced lung injury

https://doi.org/10.18632/oncotarget.13724

Changping Gu, Chenyang Dai, Yongtao Sun, Mengjie Liu, Yuelan Wang,  and Xinyi Wu
83859-83868
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Effects of dietary vitamin E deficiency on systematic pathological changes and oxidative stress in fish

Effects of dietary vitamin E deficiency on systematic pathological changes and oxidative stress in fish

https://doi.org/10.18632/oncotarget.13729

Kaiyu Wang, Erlong Wang, Zhenyang Qin, Zhen Zhou, Yi Geng,  and Defang Chen
83869-83879
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A novel mechanism underlies atrazine toxicity in quails (Coturnix Coturnix coturnix): triggering ionic disorder via disruption of ATPases

A novel mechanism underlies atrazine toxicity in quails (Coturnix Coturnix coturnix): triggering ionic disorder via disruption of ATPases

https://doi.org/10.18632/oncotarget.13794

Jia Lin, Hui-Xin Li, Lei Qin, Zheng-Hai Du, Jun Xia,  and Jin-Long Li
83880-83892
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Research Papers: Immunology

Arctigenin functions as a selective agonist of estrogen receptor β to restrict mTORC1 activation and consequent Th17 differentiation

Arctigenin functions as a selective agonist of estrogen receptor β to restrict mTORC1 activation and consequent Th17 differentiation

https://doi.org/10.18632/oncotarget.13338

Xin Wu, Bei Tong, Yan Yang, Jinque Luo, Xusheng Yuan, Zhifeng Wei, Mengfan Yue, Yufeng Xia,  and Yue Dai
83893-83906
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Ceramide activates lysosomal cathepsin B and cathepsin D to attenuate autophagy and induces ER stress to suppress myeloid-derived suppressor cells

Ceramide activates lysosomal cathepsin B and cathepsin D to attenuate autophagy and induces ER stress to suppress myeloid-derived suppressor cells

https://doi.org/10.18632/oncotarget.13438

Feiyan Liu, Xia Li, Chunwan Lu, Aiping Bai, Jacek Bielawski, Alicja Bielawska, Brendan Marshall, Patricia V. Schoenlein, Iryna O. Lebedyeva,  and Kebin Liu
83907-83925
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Recombinant Haemonchus contortus 24 kDa excretory/secretory protein (rHcES-24) modulate the immune functions of goat PBMCs in vitro

Recombinant Haemonchus contortus 24 kDa excretory/secretory protein (rHcES-24) modulate the immune functions of goat PBMCs in vitro

https://doi.org/10.18632/oncotarget.13487

Javaid Ali Gadahi, Baojie Li, Muhammad Ehsan, Shuai Wang, Zhenchao Zhang, Yujian Wang, Muhammad Waqqas Hasan, Ruofeng Yan, Xiaokai Song, Lixin Xu,  and Xiangrui Li
83926-83937
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Interleukin-8 holds promise to serve as a molecular adjuvant in DNA vaccination model against Streptococcus iniae infection in fish

Interleukin-8 holds promise to serve as a molecular adjuvant in DNA vaccination model against Streptococcus iniae infection in fish

https://doi.org/10.18632/oncotarget.13728

Erlong Wang, Bo Long, Kaiyu Wang, Jun Wang, Yang He, Xingli Wang, Qian Yang, Tao Liu, Defang Chen, Yi Geng, Xiaoli Huang, Ping Ouyang,  and Weimin Lai
83938-83950
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Chenodeoxycholic acid activates NLRP3 inflammasome and contributes to cholestatic liver fibrosis

Chenodeoxycholic acid activates NLRP3 inflammasome and contributes to cholestatic liver fibrosis

https://doi.org/10.18632/oncotarget.13796

Zizhen Gong, Jiefei Zhou, Shengnan Zhao, Chunyan Tian, Panliang Wang, Congfeng Xu, Yingwei Chen, Wei Cai,  and Jin Wu
83951-83963
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Research Papers: Autophagy and Cell Death

Aberrant localization of apoptosis protease activating factor-1 in lipid raft sub-domains of diffuse large B cell lymphomas

Aberrant localization of apoptosis protease activating factor-1 in lipid raft sub-domains of diffuse large B cell lymphomas

https://doi.org/10.18632/oncotarget.13336

Jayshree L. Hirpara, Thomas Loh, Siok Bian Ng, Wee Joo Chng,  and Shazib Pervaiz
83964-83975
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Research Papers

Tumor-associated macrophages induce vasculogenic mimicry of glioblastoma multiforme through cyclooxygenase-2 activation

Tumor-associated macrophages induce vasculogenic mimicry of glioblastoma multiforme through cyclooxygenase-2 activation

https://doi.org/10.18632/oncotarget.6930

Xiaoming Rong, Bo Huang, Shuwei Qiu, Xiangpen Li, Lei He,  and Ying Peng
83976-83986
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Relapsed diffuse large B-cell lymphoma present different genomic profiles between early and late relapses

Relapsed diffuse large B-cell lymphoma present different genomic profiles between early and late relapses

https://doi.org/10.18632/oncotarget.9793

Julien Broséus, Gaili Chen, Sébastien Hergalant, Gérard Ramstein, Nicolas Mounier, Jean-Louis Guéant, Pierre Feugier, Christian Gisselbrecht, Catherine Thieblemont,  and Rémi Houlgatte
83987-84002
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Two subtypes of colorectal tumor with distinct molecular features in familial adenomatous polyposis

Two subtypes of colorectal tumor with distinct molecular features in familial adenomatous polyposis

https://doi.org/10.18632/oncotarget.11510

Kiyoko Takane, Keisuke Matsusaka, Satoshi Ota, Masaki Fukuyo, Yao Yue, Motoi Nishimura, Eiji Sakai, Kazuyuki Matsushita, Hideaki Miyauchi, Hiroyuki Aburatani, Yukio Nakatani, Tadatoshi Takayama, Hisahiro Matsubara, Kiwamu Akagi,  and Atsushi Kaneda
84003-84016
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MiRNA203 suppresses the expression of protumorigenic STAT1 in glioblastoma to inhibit tumorigenesis

MiRNA203 suppresses the expression of protumorigenic STAT1 in glioblastoma to inhibit tumorigenesis

https://doi.org/10.18632/oncotarget.12401

Chuan He Yang, Yinan Wang, Michelle Sims, Chun Cai, Ping He, Junming Yue, Jinjun Cheng, Frederick A. Boop, Susan R. Pfeffer,  and Lawrence M. Pfeffer
84017-84029
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Chemotherapy enriches for an invasive triple-negative breast tumor cell subpopulation expressing a precursor form of N-cadherin on the cell surface

Chemotherapy enriches for an invasive triple-negative breast tumor cell subpopulation expressing a precursor form of N-cadherin on the cell surface

https://doi.org/10.18632/oncotarget.12767

Erik R. Nelson, Shenduo Li, Margaret Kennedy, Sturgis Payne, Kelly Kilibarda, Jeffrey Groth, Michelle Bowie, Edgardo Parilla-Castellar, Gustaaf de Ridder, Paul Kelly Marcom, Matthew Lyes, Bercedis L. Peterson, Michael Cook, Salvatore V. Pizzo, Donald P. McDonnell,  and Robin E. Bachelder
84030-84042
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Efficacy of splint therapy for the management of temporomandibular disorders: a meta-analysis

Efficacy of splint therapy for the management of temporomandibular disorders: a meta-analysis

https://doi.org/10.18632/oncotarget.13059

Chao Zhang, Jun-Yi Wu, Dong-Lai Deng, Bing-Yang He, Yuan Tao, Yu-Ming Niu,  and Mo-Hong Deng
84043-84053
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E-cadherin downregulation sensitizes PTEN-mutant tumors to PI3Kβ silencing

E-cadherin downregulation sensitizes PTEN-mutant tumors to PI3Kβ silencing

https://doi.org/10.18632/oncotarget.13414

África Millán-Uclés, Susana Zuluaga, Miriam Marqués, Jesus Vallejo-Díaz, Lorena Sanz, Ariel E. Cariaga-Martínez, Francisco X. Real,  and Ana C. Carrera
84054-84071
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Acquisition cancer stemness, mesenchymal transdifferentiation, and chemoresistance properties by chronic exposure of oral epithelial cells to arecoline

Acquisition cancer stemness, mesenchymal transdifferentiation, and chemoresistance properties by chronic exposure of oral epithelial cells to arecoline

https://doi.org/10.18632/oncotarget.11432

Tung Yuan Wang, Chih-Yu Peng, Shiuan-Shinn Lee, Ming-Yung Chou, Cheng-Chia Yu,  and Yu-Chao Chang
84072-84081
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In vitro comparison of conventional hyperthermia and modulated electro-hyperthermia

In vitro comparison of conventional hyperthermia and modulated electro-hyperthermia

https://doi.org/10.18632/oncotarget.11444

Kai-Lin Yang, Cheng-Chung Huang, Mau-Shin Chi, Hsin-Chien Chiang, Yu-Shan Wang, Chien-Chung Hsia, Gabor Andocs, Hsin-Ell Wang,  and Kwan-Hwa Chi
84082-84092
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activation of HERV-K Env protein is essential for tumorigenesis and metastasis of breast cancer cells

Activation of HERV-K Env protein is essential for tumorigenesis and metastasis of breast cancer cells

https://doi.org/10.18632/oncotarget.11455

Fuling Zhou, Ming Li, Yongchang Wei, Kevin Lin, Yue Lu, Jianjun Shen, Gary L. Johanning,  and Feng Wang-Johanning
84093-84117
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IPMK and β-catenin mediate PLC-β1-dependent signaling in myogenic differentiation

IPMK and β-catenin mediate PLC-β1-dependent signaling in myogenic differentiation

https://doi.org/10.18632/oncotarget.11527

Giulia Ramazzotti, Anna Maria Billi, Lucia Manzoli, Cristina Mazzetti, Alessandra Ruggeri, Christophe Erneux, Seyun Kim, Pann-Ghill Suh, Lucio Cocco,  and Irene Faenza
84118-84127
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Lunasin is a novel therapeutic agent for targeting melanoma cancer stem cells

Lunasin is a novel therapeutic agent for targeting melanoma cancer stem cells

https://doi.org/10.18632/oncotarget.11554

Chris Shidal, Numan Al-Rayyan, Kavitha Yaddanapudi,  and Keith R. Davis
84128-84141
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Application of pharmacologically induced transcriptomic profiles to interrogate PI3K-Akt-mTOR pathway activity associated with cancer patient prognosis

Application of pharmacologically induced transcriptomic profiles to interrogate PI3K-Akt-mTOR pathway activity associated with cancer patient prognosis

https://doi.org/10.18632/oncotarget.11776

Matthew H. Ung, George L. Wang, Frederick S. Varn,  and Chao Cheng
84142-84154
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The pathological behaviors and prognostic factors of Chinese and Japanese colorectal cancers from general hospitals: a comparative study of the inpatients with surgical operation

The pathological behaviors and prognostic factors of Chinese and Japanese colorectal cancers from general hospitals: a comparative study of the inpatients with surgical operation

https://doi.org/10.18632/oncotarget.12228

Xue-feng Yang, Ji-feng Zhang, Jun-jun Li, Shuang Zhao, Shuai Shi, Ji-cheng Wu, Lei Fang, Hua-mao Jiang,  and Hua-chuan Zheng
84155-84164
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Circulating microRNA124-3p, microRNA9-3p and microRNA196b-5p may be potential signatures for differential diagnosis of thyroid nodules

Circulating microRNA124-3p, microRNA9-3p and microRNA196b-5p may be potential signatures for differential diagnosis of thyroid nodules

https://doi.org/10.18632/oncotarget.12389

Sui Yu, Xiaoling Liu, Yifei Zhang, Jing Li, Shulin Chen, Haitao Zheng, Ruizhen Reng, Chenglin Zhang, Jian Chen,  and Li Chen
84165-84177
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Meta-analysis of gene expression and integrin-associated signaling pathways in papillary renal cell carcinoma subtypes

Meta-analysis of gene expression and integrin-associated signaling pathways in papillary renal cell carcinoma subtypes

https://doi.org/10.18632/oncotarget.12390

Kai Zhang, Hang-Mao Lee, Gong-Hong Wei,  and Aki Manninen
84178-84189
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metformin potentiates anti-tumor effect of resveratrol on pancreatic cancer by down-regulation of VEGF-B signaling pathway

Metformin potentiates anti-tumor effect of resveratrol on pancreatic cancer by down-regulation of VEGF-B signaling pathway

https://doi.org/10.18632/oncotarget.12391

Mengmeng Zhu, Qiong Zhang, Xiaoling Wang, Licheng Kang, Yinan Yang, Yuansheng Liu, Lei Yang, Jing Li, Liang Yang, Jie Liu, Yin Li, Lingling Zu, Yanna Shen,  and Zhi Qi
84190-84200
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The andean anticancer herbal product BIRM causes destabilization of androgen receptor and induces caspase-8 mediated-apoptosis in prostate cancer

The andean anticancer herbal product BIRM causes destabilization of androgen receptor and induces caspase-8 mediated-apoptosis in prostate cancer

https://doi.org/10.18632/oncotarget.12393

Nagarajarao Shamaladevi, Shinako Araki, Dominic A. Lyn, Rajnikanth Ayyathurai, Jie Gao, Vinata B. Lokeshwar, Hugo Navarrete,  and Bal L. Lokeshwar
84201-84213
Abstract  |  PDF  |  HTML  |  Order a Reprint

Combined targeting of SET and tyrosine kinases provides an effective therapeutic approach in human T-cell acute lymphoblastic leukemia

Combined targeting of SET and tyrosine kinases provides an effective therapeutic approach in human T-cell acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.12394

Nameeta P. Richard, Raffaella Pippa, Megan M. Cleary, Alka Puri, Deanne Tibbitts, Shawn Mahmood, Dale J. Christensen, Sophia Jeng, Shannon McWeeney, A. Thomas Look, Bill H. Chang, Jeffrey W. Tyner, Michael P. Vitek, María D. Odero, Rosalie Sears,  and Anupriya Agarwal
84214-84227
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Interaction between susceptibility loci in cGAS-STING pathway, MHC gene and HPV infection on the risk of cervical precancerous lesions in Chinese population

Interaction between susceptibility loci in cGAS-STING pathway, MHC gene and HPV infection on the risk of cervical precancerous lesions in Chinese population

https://doi.org/10.18632/oncotarget.12399

Di Xiao, Weihuang Huang, Meiling Ou, Congcong Guo, Xingguang Ye, Yang Liu, Man Wang, Baohuan Zhang, Na Zhang, Shiqi Huang, Jiankun Zang, Zixing Zhou, Zihao Wen, Chengli Zeng, Chenfei Wu, Chuican Huang, Xiangcai Wei, Guang Yang,  and Chunxia Jing
84228-84238
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Upregulation of HSF1 in estrogen receptor positive breast cancer

Upregulation of HSF1 in estrogen receptor positive breast cancer

https://doi.org/10.18632/oncotarget.12438

Yesim Gökmen-Polar,  and Sunil Badve
84239-84245
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Generation of V α13/β21+T cell specific target CML cells by TCR gene transfer

Generation of V α13/β21+T cell specific target CML cells by TCR gene transfer

https://doi.org/10.18632/oncotarget.12441

Xianfeng Zha, Ling Xu, Shaohua Chen, Lijian Yang, Yikai Zhang, Yuhong Lu, Zhi Yu, Bo Li, Xiuli Wu, Wenjie Zheng,  and Yangqiu Li
84246-84257
Abstract  |  PDF  |  HTML  |  Order a Reprint

LDB1 overexpression is a negative prognostic factor in colorectal cancer

LDB1 overexpression is a negative prognostic factor in colorectal cancer

https://doi.org/10.18632/oncotarget.12481

Sebastián A. García, Anka Swiersy, Praveen Radhakrishnan, Vittorio Branchi, Lahiri Kanth Nanduri, Balázs Győrffy, Alexander M. Betzler, Ulrich Bork, Christoph Kahlert, Christoph Reißfelder, Nuh N. Rahbari, Jürgen Weitz,  and Sebastian Schölch
84258-84270
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impact of Polo-like kinase 1 inhibitors on human adipose tissue-derived mesenchymal stem cells

Impact of Polo-like kinase 1 inhibitors on human adipose tissue-derived mesenchymal stem cells

https://doi.org/10.18632/oncotarget.12482

Andreas Ritter, Alexandra Friemel, Nina-Naomi Kreis, Frank Louwen,  and Juping Yuan
84271-84285
Abstract  |  PDF  |  HTML  |  Order a Reprint

The hedgehog inhibitor GANT61 sensitizes prostate cancer cells to ionizing radiation both in vitro and in vivo

The hedgehog inhibitor GANT61 sensitizes prostate cancer cells to ionizing radiation both in vitro and in vivo

https://doi.org/10.18632/oncotarget.12483

Annelies Gonnissen, Sofie Isebaert, Chad M McKee, Rüveyda Dok, Karin Haustermans,  and Ruth J Muschel
84286-84298
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dicer suppresses MMP-2-mediated invasion and VEGFA-induced angiogenesis and serves as a promising prognostic biomarker in human clear cell renal cell carcinoma

Dicer suppresses MMP-2-mediated invasion and VEGFA-induced angiogenesis and serves as a promising prognostic biomarker in human clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.12520

Yan-Su Chen, Fei Meng, Hai-Long Li, Qing-Hua Liu, Ping-Fu Hou, Jin Bai,  and Jun-Nian Zheng
84299-84313
Abstract  |  PDF  |  HTML  |  Order a Reprint

Compound genetically engineered mouse models of cancer reveal dual targeting of ALK1 and endoglin as a synergistic opportunity to impinge on angiogenic TGF-β signaling

Compound genetically engineered mouse models of cancer reveal dual targeting of ALK1 and endoglin as a synergistic opportunity to impinge on angiogenic TGF-β signaling

https://doi.org/10.18632/oncotarget.12604

Nikolas M. Eleftheriou, Jonas Sjölund, Matteo Bocci, Eliane Cortez, Se-Jin Lee, Sara I. Cunha,  and Kristian Pietras
84314-84325
Abstract  |  PDF  |  HTML  |  Order a Reprint

Ral A, via activating the mitotic checkpoint, sensitizes cells lacking a functional Nf1 to apoptosis in the absence of protein kinase C

Ral A, via activating the mitotic checkpoint, sensitizes cells lacking a functional Nf1 to apoptosis in the absence of protein kinase C

https://doi.org/10.18632/oncotarget.12607

Suthakar Ganapathy, Johan B Fagman, Ling Shen, Tianqi Yu, Xiaodong Zhou, Wei Dai, Alexandros Makriyannis,  and Changyan Chen
84326-84337
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

H2S-releasing nanoemulsions: a new formulation to inhibit tumor cells proliferation and improve tissue repair

H2S-releasing nanoemulsions: a new formulation to inhibit tumor cells proliferation and improve tissue repair

https://doi.org/10.18632/oncotarget.12609

Matteo Ciocci, Egidio Iorio, Felicia Carotenuto, Haneen A. Khashoggi, Francesca Nanni,  and Sonia Melino
84338-84358
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inducible expression of cancer-testis antigens in human prostate cancer

Inducible expression of cancer-testis antigens in human prostate cancer

https://doi.org/10.18632/oncotarget.12711

Erika Heninger, Timothy E.G. Krueger, Stephanie M. Thiede, Jamie M. Sperger, Brianna L. Byers, Madison R. Kircher, David Kosoff, Bing Yang, David F. Jarrard, Douglas G. McNeel,  and Joshua M. Lang
84359-84374
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FOXC1 promotes melanoma by activating MST1R/PI3K/AKT pathway and is associated with poor prognosis in melanoma

FOXC1 promotes melanoma by activating MST1R/PI3K/AKT pathway and is associated with poor prognosis in melanoma

https://doi.org/10.18632/oncotarget.11224

Jinhua Wang, Li Li, Shiwei Liu, Ying Zhao, Lin Wang,  and Guanhua Du
84375-84387
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Celastrol increases osteosarcoma cell lysis by γδ T cells through up-regulation of death receptors

Celastrol increases osteosarcoma cell lysis by γδ T cells through up-regulation of death receptors

https://doi.org/10.18632/oncotarget.12756

Zhaoxu Li, Junzhe Zhang, Jicun Tang,  and Ruiying Wang
84388-84397
Abstract  |  PDF  |  HTML  |  Order a Reprint

Next-generation sequencing identifies articular cartilage and subchondral bone miRNAs after ESWT on early osteoarthritis knee

Next-generation sequencing identifies articular cartilage and subchondral bone miRNAs after ESWT on early osteoarthritis knee

https://doi.org/10.18632/oncotarget.11331

Jai-Hong Cheng, Ching-Jen Wang, Shi-Hao Su, Chien-Yiu Huang,  and Shan-Ling Hsu
84398-84407
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Diagnostic and prognostic value of serum MACC1 in breast cancer patients

Diagnostic and prognostic value of serum MACC1 in breast cancer patients

https://doi.org/10.18632/oncotarget.12910

Weige Tan, Xinhua Xie, Laisheng Li, Hailin Tang, Xigang Ye, Lun Chen, Wei Tang, Jin Gao, Lingxiao Pan, Xiaoshen Zhang, Feng Ye, Xing Li, Lu Yang, Xiaoming Xie,  and Wenbo Zheng
84408-84415
Abstract  |  PDF  |  HTML  |  Order a Reprint

Hypermethylation of the HIC1 promoter and aberrant expression of HIC1/SIRT1 contribute to the development of thyroid papillary carcinoma

Hypermethylation of the HIC1 promoter and aberrant expression of HIC1/SIRT1 contribute to the development of thyroid papillary carcinoma

https://doi.org/10.18632/oncotarget.12936

Wenyi Wu, Liting Zhang, Jianqing Lin, Hanwei Huang, Bai Shi, Xingong Lin, Zhongxin Huang, Chaoyang Wang, Jianlong Qiu,  and Xiaolong Wei
84416-84427
Abstract  |  PDF  |  HTML  |  Order a Reprint

MED12 mutations in breast phyllodes tumors: evidence of temporal tumoral heterogeneity and identification of associated critical signaling pathways

MED12 mutations in breast phyllodes tumors: evidence of temporal tumoral heterogeneity and identification of associated critical signaling pathways

https://doi.org/10.18632/oncotarget.12991

Marick Laé, Sophie Gardrat, Sophie Rondeau, Camille Richardot, Martial Caly, Walid Chemlali, Sophie Vacher, Jérôme Couturier, Odette Mariani, Philippe Terrier,  and Ivan Bièche
84428-84438
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ammonium tetrathiomolybdate treatment targets the copper transporter ATP7A and enhances sensitivity of breast cancer to cisplatin

Ammonium tetrathiomolybdate treatment targets the copper transporter ATP7A and enhances sensitivity of breast cancer to cisplatin

https://doi.org/10.18632/oncotarget.12992

Cristine L. Chisholm, Haitao Wang, Ada Hang-Heng Wong, Guelaguetza Vazquez-Ortiz, Weiping Chen, Xiaoling Xu,  and Chu-Xia Deng
84439-84452
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

EZH2 inhibition promotes epithelial-to-mesenchymal transition in ovarian cancer cells

EZH2 inhibition promotes epithelial-to-mesenchymal transition in ovarian cancer cells

https://doi.org/10.18632/oncotarget.11497

Horacio Cardenas, Janice Zhao, Edyta Vieth, Kenneth P. Nephew,  and Daniela Matei
84453-84467
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A network meta-analysis on the efficacy of sixteen targeted drugs in combination with chemotherapy for treatment of advanced/metastatic colorectal cancer

A network meta-analysis on the efficacy of sixteen targeted drugs in combination with chemotherapy for treatment of advanced/metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.12994

Dan-Zeng Ba-Sang, Zi-Wen Long, Hao Teng, Xu-Peng Zhao, Jian Qiu,  and Ming-Shan Li
84468-84479
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Upregulation of long noncoding RNA HOTTIP promotes metastasis of esophageal squamous cell carcinoma via induction of EMT

Upregulation of long noncoding RNA HOTTIP promotes metastasis of esophageal squamous cell carcinoma via induction of EMT

https://doi.org/10.18632/oncotarget.12995

Xuemei Chen, Hongyu Han, Yuqi Li, Qiongxia Zhang, Kailan Mo,  and Size Chen
84480-84485
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Human sulfatase 1 exerts anti-tumor activity by inhibiting the AKT/ CDK4 signaling pathway in melanoma

Human sulfatase 1 exerts anti-tumor activity by inhibiting the AKT/ CDK4 signaling pathway in melanoma

https://doi.org/10.18632/oncotarget.12996

Xiaoli Lou, Bin Sun, Jianxing Song, Yicun Wang, Junhao Jiang, Yang Xu, Zeqiang Ren,  and Changqing Su
84486-84495
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p16INK4a suppresses BRCA1-deficient mammary tumorigenesis

p16INK4a suppresses BRCA1-deficient mammary tumorigenesis

https://doi.org/10.18632/oncotarget.13015

Alexandria Scott, Feng Bai, Ho Lam Chan, Shiqin Liu, Jinshan Ma, Joyce M Slingerland, David J. Robbins, Anthony J. Capobianco,  and Xin-Hai Pei
84496-84507
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-21 and MiR-155 promote non-small cell lung cancer progression by downregulating SOCS1, SOCS6, and PTEN

MiR-21 and MiR-155 promote non-small cell lung cancer progression by downregulating SOCS1, SOCS6, and PTEN

https://doi.org/10.18632/oncotarget.13022

Xinying Xue, Yuxia Liu, Yong Wang, Mingming Meng, Kaifei Wang, Xuefeng Zang, Sheng Zhao, Xiaohua Sun, Lei Cui, Lei Pan,  and Sanhong Liu
84508-84519
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Vitexin suppresses autophagy to induce apoptosis in hepatocellular carcinoma via activation of the JNK signaling pathway

Vitexin suppresses autophagy to induce apoptosis in hepatocellular carcinoma via activation of the JNK signaling pathway

https://doi.org/10.18632/oncotarget.11731

Zhen Wang, Shi-Peng Li, Yan-Jie Xu, Yao Yu, Yi-Jie Ding, Wen-Li Yu, Rong-Xin Zhang, Hai-Ming Zhang,  and Hong-Yin Du
84520-84532
Abstract  |  PDF  |  HTML  |  Order a Reprint

A network meta-analysis for toxicity of eight chemotherapy regimens in the treatment of metastatic/advanced breast cancer

A network meta-analysis for toxicity of eight chemotherapy regimens in the treatment of metastatic/advanced breast cancer

https://doi.org/10.18632/oncotarget.13023

Xiao-Hua Zhang, Shuai Hao, Bo Gao, Wu-Guo Tian, Yan Jiang, Shu Zhang, Ling-Ji Guo,  and Dong-Lin Luo
84533-84543
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Meta-analysis of laparoscopic versus open liver resection for colorectal liver metastases

Meta-analysis of laparoscopic versus open liver resection for colorectal liver metastases

https://doi.org/10.18632/oncotarget.13026

Zhi-qiang Tian, Xiao-fang Su, Zhi-yong Lin, Meng-chao Wu, Li-xin Wei,  and Jia He
84544-84555
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Loss of phosphodiesterase 4D mediates acquired triapine resistance via Epac-Rap1-Integrin signaling

Loss of phosphodiesterase 4D mediates acquired triapine resistance via Epac-Rap1-Integrin signaling

https://doi.org/10.18632/oncotarget.11821

Walter Miklos, Petra Heffeter, Christine Pirker, Sonja Hager, Christian Kowol, Sushilla van Schoonhoven, Mirjana Stojanovic, Bernhard Keppler,  and Walter Berger
84556-84574
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Small heterodimer partner 1 directly interacts with NS5A viral protein and has a key role in HCV related liver cell transformation

Small heterodimer partner 1 directly interacts with NS5A viral protein and has a key role in HCV related liver cell transformation

https://doi.org/10.18632/oncotarget.12144

Beatrice Conti, Cristiana Porcu, Carmela Viscomi, Antonella Minutolo, Susan Costantini, Marco Corazzari, Gino Iannucci, Barbara Barbaro,  and Clara Balsano
84575-84586
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FGFR3, as a receptor tyrosine kinase, is associated with differentiated biological functions and improved survival of glioma patients

FGFR3, as a receptor tyrosine kinase, is associated with differentiated biological functions and improved survival of glioma patients

https://doi.org/10.18632/oncotarget.13139

Zheng Wang, Chuanbao Zhang, Lihua Sun, Jingshan Liang, Xing Liu, Guanzhang Li, Kun Yao, Wei Zhang,  and Tao Jiang
84587-84593
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combining a GSI and BCL-2 inhibitor to overcome melanoma’s resistance to current treatments

Combining a GSI and BCL-2 inhibitor to overcome melanoma’s resistance to current treatments

https://doi.org/10.18632/oncotarget.13141

Nabanita Mukherjee, Adam Almeida, Katie A. Partyka, Yan Lu, Josianna V. Schwan, Karoline Lambert, Madison Rogers, William A Robinson, Steven E Robinson, Allison J Applegate, Carol M Amato, Yuchun Luo, Mayumi Fujita, David A. Norris,  and Yiqun G. Shellman
84594-84607
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Heparan sulfate hexasaccharide selectively inhibits cancer stem cells self-renewal by activating p38 MAP kinase

Heparan sulfate hexasaccharide selectively inhibits cancer stem cells self-renewal by activating p38 MAP kinase

https://doi.org/10.18632/oncotarget.12358

Nirmita J. Patel, Chetna Sharon, Somesh Baranwal, Rio S. Boothello, Umesh R. Desai,  and Bhaumik B. Patel
84608-84622
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PPARα, a predictor of patient survival in glioma, inhibits cell growth through the E2F1/miR-19a feedback loop

PPARα, a predictor of patient survival in glioma, inhibits cell growth through the E2F1/miR-19a feedback loop

https://doi.org/10.18632/oncotarget.13170

Yan Shi, Tao Tao, Ning Liu, WenKang Luan, Jin Qian, Rui Li, Qi Hu, Yan Wei, Junxia Zhang,  and Yongping You
84623-84633
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Unraveling the expression of the oncogene YAP1, a Wnt/beta-catenin target, in adrenocortical tumors and its association with poor outcome in pediatric patients

Unraveling the expression of the oncogene YAP1, a Wnt/beta-catenin target, in adrenocortical tumors and its association with poor outcome in pediatric patients

https://doi.org/10.18632/oncotarget.12382

Rafael H. Abduch, Ana Carolina Bueno, Leticia F. Leal, Marcelo M. Cavalcanti, Débora C. Gomes, Silvia R. Brandalise, Maria J. Masterallo, José A. Yunes, Carlos E. Martinelli Jr, Luiz G. Tone, Silvio Tucci, Carlos A.F. Molina, Fernando S. Ramalho, Ayrton C. Moreira, Izilda A. Cardinalli, Carlos A. Scrideli, Leandra N.Z. Ramalho, Margaret de Castro,  and Sonir R. Antonini
84634-84644
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Keratin 13 expression reprograms bone and brain metastases of human prostate cancer cells

Keratin 13 expression reprograms bone and brain metastases of human prostate cancer cells

https://doi.org/10.18632/oncotarget.13175

Qinlong Li, Lijuan Yin, Lawrence W. Jones, Gina C-Y Chu, Jason B-Y. Wu, Jen-Ming Huang, Quanlin Li, Sungyong You, Jayoung Kim, Yi-Tsung Lu, Stefan Mrdenovic, Ruoxiang Wang, Michael R. Freeman, Isla Garraway, Michael S. Lewis, Leland W.K. Chung,  and Haiyen E. Zhau
84645-84657
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pyroptosis is involved in the pathogenesis of human hepatocellular carcinoma

Pyroptosis is involved in the pathogenesis of human hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.12384

Qun Chu, Yanan Jiang, Wei Zhang, Chaoqian Xu, Weijie Du, Gulnara Tuguzbaeva, Ying Qin, Anqi Li, Liangshuan Zhang, Guiyuan Sun, Yongqiao Cai, Qiang Feng, Guiyang Li, Yanyao Li, Zhimin Du, Yunlong Bai,  and Baofeng Yang
84658-84665
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical data from the real world: efficacy of Crizotinib in Chinese patients with advanced ALK-rearranged non-small cell lung cancer and brain metastases

Clinical data from the real world: efficacy of Crizotinib in Chinese patients with advanced ALK-rearranged non-small cell lung cancer and brain metastases

https://doi.org/10.18632/oncotarget.13179

Puyuan Xing, Shouzheng Wang, Xuezhi Hao, Tongtong Zhang,  and Junling Li
84666-84674
Abstract  |  PDF  |  HTML  |  Order a Reprint

OTX015 (MK-8628), a novel BET inhibitor, exhibits antitumor activity in non-small cell and small cell lung cancer models harboring different oncogenic mutations

OTX015 (MK-8628), a novel BET inhibitor, exhibits antitumor activity in non-small cell and small cell lung cancer models harboring different oncogenic mutations

https://doi.org/10.18632/oncotarget.13181

Maria E. Riveiro, Lucile Astorgues-Xerri, Ramiro Vazquez, Roberta Frapolli, Ivo Kwee, Andrea Rinaldi, Elodie Odore, Keyvan Rezai, Mohamed Bekradda, Giorgio Inghirami, Maurizio D’Incalci, Kay Noel, Esteban Cvitkovic, Eric Raymond,  and Francesco Bertoni
84675-84687
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma

MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.12423

Hongqing Zhuang, Jing Bai, Joe Y. Chang, Zhiyong Yuan,  and Ping Wang
84688-84694
Abstract  |  PDF  |  HTML  |  Order a Reprint

Enhanced circulating transforming growth factor beta 1 is causally associated with an increased risk of hepatocellular carcinoma: a mendelian randomization meta-analysis

Enhanced circulating transforming growth factor beta 1 is causally associated with an increased risk of hepatocellular carcinoma: a mendelian randomization meta-analysis

https://doi.org/10.18632/oncotarget.13218

Wei-Qun LU, Ji-Liang QIU, Zhi-Liang HUANG,  and Hai-Ying LIU
84695-84704
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KCNJ3 is a new independent prognostic marker for estrogen receptor positive breast cancer patients

KCNJ3 is a new independent prognostic marker for estrogen receptor positive breast cancer patients

https://doi.org/10.18632/oncotarget.13224

Sarah Kammerer, Armin Sokolowski, Hubert Hackl, Dieter Platzer, Stephan Wenzel Jahn, Amin El-Heliebi, Daniela Schwarzenbacher, Verena Stiegelbauer, Martin Pichler, Simin Rezania, Heidelinde Fiegl, Florentia Peintinger, Peter Regitnig, Gerald Hoefler, Wolfgang Schreibmayer,  and Thomas Bauernhofer
84705-84717
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The Aurora kinase A inhibitor TC-A2317 disrupts mitotic progression and inhibits cancer cell proliferation

The Aurora kinase A inhibitor TC-A2317 disrupts mitotic progression and inhibits cancer cell proliferation

https://doi.org/10.18632/oncotarget.12448

Yoo Hong Min, Wootae Kim,  and Ja-Eun Kim
84718-84735
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A phase 1 study of oral ridaforolimus in pediatric patients with advanced solid tumors

A phase 1 study of oral ridaforolimus in pediatric patients with advanced solid tumors

https://doi.org/10.18632/oncotarget.12450

Andrew D.J. Pearson, Sara M. Federico, Isabelle Aerts, Darren R. Hargrave, Steven G. DuBois, Robert Iannone, Ryan D. Geschwindt, Ruixue Wang, Frank G. Haluska, Tanya M. Trippett,  and Birgit Geoerger
84736-84747
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gremlin inhibits UV-induced skin cell damages via activating VEGFR2-Nrf2 signaling

Gremlin inhibits UV-induced skin cell damages via activating VEGFR2-Nrf2 signaling

https://doi.org/10.18632/oncotarget.12454

Chao Ji, Jin-wen Huang, Qiu-yun Xu, Jing Zhang, Meng-ting Lin, Ying Tu, Li He, Zhi-gang Bi,  and Bo Cheng
84748-84757
Abstract  |  PDF  |  HTML  |  Order a Reprint

Blood and lung microRNAs as biomarkers of pulmonary tumorigenesis in cigarette smoke-exposed mice

Blood and lung microRNAs as biomarkers of pulmonary tumorigenesis in cigarette smoke-exposed mice

https://doi.org/10.18632/oncotarget.12475

Alberto Izzotti, Roumen Balansky, Gancho Ganchev, Marietta Iltcheva, Mariagrazia Longobardi, Alessandra Pulliero, Marta Geretto, Rosanna T. Micale, Sebastiano La Maestra, Mark Steven Miller, Vernon E. Steele,  and Silvio De Flora
84758-84774
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dot1l expression predicts adverse postoperative prognosis of patients with clear-cell renal cell carcinoma

Dot1l expression predicts adverse postoperative prognosis of patients with clear-cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.12476

Yang Qu, Li Liu, Jiajun Wang, Wei Xi, Yu Xia, Qi Bai, Ying Xiong, Qilai Long, Jiejie Xu,  and Jianming Guo
84775-84784
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

DNA methylation promotes paired box 2 expression via myeloid zinc finger 1 in endometrial cancer

DNA methylation promotes paired box 2 expression via myeloid zinc finger 1 in endometrial cancer

https://doi.org/10.18632/oncotarget.12626

Nan Jia, Jieyu Wang, Qing Li, Xiang Tao, Kaikai Chang, Keqin Hua, Yinhua Yu, Kwong-Kwok Wong,  and Weiwei Feng
84785-84797
Abstract  |  PDF  |  HTML  |  Order a Reprint

C5a receptor (CD88) promotes motility and invasiveness of gastric cancer by activating RhoA

C5a receptor (CD88) promotes motility and invasiveness of gastric cancer by activating RhoA

https://doi.org/10.18632/oncotarget.12656

Takayoshi Kaida, Hidetoshi Nitta, Yuki Kitano, Kensuke Yamamura, Kota Arima, Daisuke Izumi, Takaaki Higashi, Junji Kurashige, Katsunori Imai, Hiromitsu Hayashi, Masaaki Iwatsuki, Takatsugu Ishimoto, Daisuke Hashimoto, Yoichi Yamashita, Akira Chikamoto, Takahisa Imanura, Takatoshi Ishiko, Toru Beppu,  and Hideo Baba
84798-84809
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Different BCR/Abl protein suppression patterns as a converging trait of chronic myeloid leukemia cell adaptation to energy restriction

Different BCR/Abl protein suppression patterns as a converging trait of chronic myeloid leukemia cell adaptation to energy restriction

https://doi.org/10.18632/oncotarget.13319

Silvia Bono, Matteo Lulli, Vito Giuseppe D’Agostino, Federico Di Gesualdo, Rosa Loffredo, Maria Grazia Cipolleschi, Alessandro Provenzani, Elisabetta Rovida,  and Persio Dello Sbarba
84810-84825
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-384 inhibits human colorectal cancer metastasis by targeting KRAS and CDC42

MiR-384 inhibits human colorectal cancer metastasis by targeting KRAS and CDC42

https://doi.org/10.18632/oncotarget.12704

Yong-Xia Wang, Yan-Ru Chen, Shan-Shan Liu, Ya-Ping Ye, Hong-Li Jiao, Shu-Yang Wang, Zhi-Yuan Xiao, Wen-Ting Wei, Jun-Feng Qiu, Li Liang, Wen-Ting Liao,  and Yan-Qing Ding
84826-84838
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway

H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway

https://doi.org/10.18632/oncotarget.13321

Shanmin Zhao, Li Li, Shiyong Wang, Chenlin Yu, Bang Xiao, Lifang Lin, Wei Cong, Jishuai Cheng, Wenjing Yang, Wei Sun,  and Shufang Cui
84839-84850
Abstract  |  PDF  |  HTML  |  Order a Reprint

Diagnostic value of fibulin-3 for malignant pleural mesothelioma: A systematic review and meta-analysis

Diagnostic value of fibulin-3 for malignant pleural mesothelioma: A systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.12707

Ran Ren, Pengpeng Yin, Yan Zhang, Jianyun Zhou, Yixing Zhou, Rufu Xu, Hai Lin,  and Chunji Huang
84851-84859
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Heregulin-expressing HER2-positive breast and gastric cancer exhibited heterogeneous susceptibility to the anti-HER2 agents lapatinib, trastuzumab and T-DM1

Heregulin-expressing HER2-positive breast and gastric cancer exhibited heterogeneous susceptibility to the anti-HER2 agents lapatinib, trastuzumab and T-DM1

https://doi.org/10.18632/oncotarget.12743

Yoshikane Nonagase, Kimio Yonesaka, Hisato Kawakami, Satomi Watanabe, Koji Haratani, Takayuki Takahama, Naoki Takegawa, Hiroto Ueda, Junko Tanizaki, Hidetoshi Hayashi, Takeshi Yoshida, Masayuki Takeda, Yasutaka Chiba, Takao Tamura, Kazuhiko Nakagawa,  and Junji Tsurutani
84860-84871
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nucleotide excision repair pathway gene polymorphisms are linked to breast cancer risk in a Chinese population

Nucleotide excision repair pathway gene polymorphisms are linked to breast cancer risk in a Chinese population

https://doi.org/10.18632/oncotarget.12744

Bang-shun He, Tao Xu, Yu-qin Pan, Han-jin Wang, William C. Cho, Kang Lin, Hui-ling Sun, Tian-yi Gao,  and Shu-kui Wang
84872-84882
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hepatitis B virus X protein influences enrichment profiles of H3K9me3 on promoter regions in human hepatoma cell lines

Hepatitis B virus X protein influences enrichment profiles of H3K9me3 on promoter regions in human hepatoma cell lines

https://doi.org/10.18632/oncotarget.12751

Di-Yi Wang, Shu-Hong An, Lei Liu, Shan-Shan Bai, Kai-Xiang Wu, Rong Zhu,  and Zhao-Jin Wang
84883-84892
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevated expression of ZNF217 promotes prostate cancer growth by restraining ferroportin-conducted iron egress

Elevated expression of ZNF217 promotes prostate cancer growth by restraining ferroportin-conducted iron egress

https://doi.org/10.18632/oncotarget.12753

Xingkang Jiang, Changwen Zhang, Shiyong Qi, Shanqi Guo, Yue Chen, E Du, Hongtuan Zhang, Xiaoming Wang, Ranlu Liu, Baomin Qiao, Kuo Yang, Zhihong Zhang,  and Yong Xu
84893-84906
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MKP-1 attenuates LPS-induced blood-testis barrier dysfunction and inflammatory response through p38 and IκBα pathways

MKP-1 attenuates LPS-induced blood-testis barrier dysfunction and inflammatory response through p38 and IκBα pathways

https://doi.org/10.18632/oncotarget.12823

Yiqing Pan, Yue Liu, Li Wang, Feng Xue, Yanqin Hu, Ran Hu,  and Chen Xu
84907-84923
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ultraviolet radiation-induced differential microRNA expression in the skin of hairless SKH1 mice, a widely used mouse model for dermatology research

Ultraviolet radiation-induced differential microRNA expression in the skin of hairless SKH1 mice, a widely used mouse model for dermatology research

https://doi.org/10.18632/oncotarget.12913

Ashok Singh, Estelle Willems, Anupama Singh, Irene M. Ong,  and Ajit K. Verma
84924-84937
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Alteration of colonic epithelial cell differentiation in mice deficient for glucosaminyl N-deacetylase/N-sulfotransferase 4

Alteration of colonic epithelial cell differentiation in mice deficient for glucosaminyl N-deacetylase/N-sulfotransferase 4

https://doi.org/10.18632/oncotarget.12915

Tzu-Ming Jao, Ya-Lin Li, Shu-Wha Lin, Sheng-Tai Tzeng, I-Shing Yu, Sou-Jhy Yen, Ming-Hong Tsai,  and Ya-Chien Yang
84938-84950
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PD 0332991, a selective cyclin D kinase 4/6 inhibitor, sensitizes lung cancer cells to treatment with epidermal growth factor receptor tyrosine kinase inhibitors

PD 0332991, a selective cyclin D kinase 4/6 inhibitor, sensitizes lung cancer cells to treatment with epidermal growth factor receptor tyrosine kinase inhibitors

https://doi.org/10.18632/oncotarget.13069

Minghui Liu, Song Xu, Yuli Wang, Ying Li, Yongwen Li, Hongbing Zhang, Hongyu Liu,  and Jun Chen
84951-84964
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oncolytic adenovirus coexpressing interleukin-12 and shVEGF restores antitumor immune function and enhances antitumor efficacy

Oncolytic adenovirus coexpressing interleukin-12 and shVEGF restores antitumor immune function and enhances antitumor efficacy

https://doi.org/10.18632/oncotarget.13087

Hyo Min Ahn, Jin Woo Hong,  and Chae-Ok Yun
84965-84980
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mutation analysis of a Chinese family with oculocutaneous albinism

Mutation analysis of a Chinese family with oculocutaneous albinism

https://doi.org/10.18632/oncotarget.13109

Xiong Wang, Yaowu Zhu, Na Shen, Jing Peng, Chunyu Wang, Haiyi Liu,  and Yanjun Lu
84981-84988
Abstract  |  PDF  |  HTML  |  Order a Reprint

Induction of mitochondria-mediated apoptosis and PI3K/Akt/ mTOR-mediated autophagy by aflatoxin B2 in hepatocytes of broilers

Induction of mitochondria-mediated apoptosis and PI3K/Akt/ mTOR-mediated autophagy by aflatoxin B2 in hepatocytes of broilers

https://doi.org/10.18632/oncotarget.13356

Binlong Chen, Diyan Li, Miao Li, Sichen Li, Kenan Peng, Xian Shi, Lanyun Zhou, Pu Zhang, Zhongxian Xu, Huadong Yin, Yan Wang, Xiaoling Zhao,  and Qing Zhu
84989-84998
Abstract  |  PDF  |  HTML  |  Order a Reprint

PTEN dephosphorylates AKT to prevent the expression of GLUT1 on plasmamembrane and to limit glucose consumption in cancer cells

PTEN dephosphorylates AKT to prevent the expression of GLUT1 on plasmamembrane and to limit glucose consumption in cancer cells

https://doi.org/10.18632/oncotarget.13113

Suratchanee Phadngam, Andrea Castiglioni, Alessandra Ferraresi, Federica Morani, Carlo Follo,  and Ciro Isidoro
84999-85020
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EGF induces epithelial-mesenchymal transition through phospho-Smad2/3-Snail signaling pathway in breast cancer cells

EGF induces epithelial-mesenchymal transition through phospho-Smad2/3-Snail signaling pathway in breast cancer cells

https://doi.org/10.18632/oncotarget.13116

Jinkyoung Kim, Jienan Kong, Hyeyoon Chang, Hayeon Kim,  and Aeree Kim
85021-85032
Abstract  |  PDF  |  HTML  |  Order a Reprint

Inhibition of Chk1 with the small molecule inhibitor V158411 induces DNA damage and cell death in an unperturbed S-phase

Inhibition of Chk1 with the small molecule inhibitor V158411 induces DNA damage and cell death in an unperturbed S-phase

https://doi.org/10.18632/oncotarget.13119

Joanne Wayne, Teresa Brooks,  and Andrew J. Massey
85033-85048
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mechanisms of transcriptional activation of the stimulator of interferon genes by transcription factors CREB and c-Myc

Mechanisms of transcriptional activation of the stimulator of interferon genes by transcription factors CREB and c-Myc

https://doi.org/10.18632/oncotarget.13183

Yan-Yan Wang, Rui Jin, Guo-Ping Zhou,  and Hua-Guo Xu
85049-85057
Abstract  |  PDF  |  HTML  |  Order a Reprint

Expressions of miR-30c and let-7a are inversely correlated with HMGA2 expression in squamous cell carcinoma of the vulva

Expressions of miR-30c and let-7a are inversely correlated with HMGA2 expression in squamous cell carcinoma of the vulva

https://doi.org/10.18632/oncotarget.13187

Antonio Agostini, Marta Brunetti, Ben Davidson, Claes G. Trope, Sverre Heim, Ioannis Panagopoulos,  and Francesca Micci
85058-85062
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Targeted depletion of PIK3R2 induces regression of lung squamous cell carcinoma

Targeted depletion of PIK3R2 induces regression of lung squamous cell carcinoma

https://doi.org/10.18632/oncotarget.13195

Jesús Vallejo-Díaz, Manuel Olazabal-Morán, Ariel E. Cariaga-Martínez, María J. Pajares, Juana M. Flores, Ruben Pio, Luis M. Montuenga,  and Ana Clara Carrera
85063-85078
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IL-37 suppresses hepatocellular carcinoma growth by converting pSmad3 signaling from JNK/pSmad3L/c-Myc oncogenic signaling to pSmad3C/P21 tumor-suppressive signaling

IL-37 suppresses hepatocellular carcinoma growth by converting pSmad3 signaling from JNK/pSmad3L/c-Myc oncogenic signaling to pSmad3C/P21 tumor-suppressive signaling

https://doi.org/10.18632/oncotarget.13196

Rui Liu, Chengyong Tang, Ai Shen, Huating Luo, Xufu Wei, Daofeng Zheng, Chao Sun, Zhongtang Li, Di Zhu, Tingting Li,  and Zhongjun Wu
85079-85096
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Subsite-specific association of DEAD box RNA helicase DDX60 with the development and prognosis of oral squamous cell carcinoma

Subsite-specific association of DEAD box RNA helicase DDX60 with the development and prognosis of oral squamous cell carcinoma

https://doi.org/10.18632/oncotarget.13197

Ting-Ying Fu, Chao-Nan Wu, Huei-Cin Sie, Jiin-Tsuey Cheng, Yaoh-Shiang Lin, Huei-Han Liou, Yu-Kai Tseng, Chih-Wen Shu, Kuo-Wang Tsai, Leing-Ming Yen, Hui-Wen Tseng, Ching-Jiunn Tseng, Luo-Ping Ger,  and Pei-Feng Liu
85097-85108
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RanBPM (RanBP9) regulates mouse c-Kit receptor level and is essential for normal development of bone marrow progenitor cells

RanBPM (RanBP9) regulates mouse c-Kit receptor level and is essential for normal development of bone marrow progenitor cells

https://doi.org/10.18632/oncotarget.13198

Sandrine Puverel, Erkan Kiris, Satyendra Singh, Kimberly D. Klarmann, Vincenzo Coppola, Jonathan R. Keller,  and Lino Tessarollo
85109-85123
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combination of COX-2 expression and PIK3CA mutation as prognostic and predictive markers for celecoxib treatment in breast cancer

Combination of COX-2 expression and PIK3CA mutation as prognostic and predictive markers for celecoxib treatment in breast cancer

https://doi.org/10.18632/oncotarget.13200

Sandrine Tury, Véronique Becette, Franck Assayag, Sophie Vacher, Camille Benoist, Maud Kamal, Elisabetta Marangoni, Ivan Bièche, Florence Lerebours,  and Céline Callens
85124-85141
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevated serum granulocyte-macrophage colony-stimulating factor levels during radiotherapy predict favorable outcomes in lung and esophageal cancer

Elevated serum granulocyte-macrophage colony-stimulating factor levels during radiotherapy predict favorable outcomes in lung and esophageal cancer

https://doi.org/10.18632/oncotarget.13202

Guodong Deng, Pingping Hu, Jingxin Zhang, Qiqi Liu, Ning Liang, Jian Xie, Lili Qiao, Hui Luo, Deguo Xu, Fengjun Liu, Xinshuang Yu, Zhen liu, Yajuan Lv,  and Jiandong Zhang
85142-85150
Abstract  |  PDF  |  HTML  |  Order a Reprint

Jumonji domain-containing protein 1A promotes cell growth and progression via transactivation of c-Myc expression and predicts a poor prognosis in cervical cancer

Jumonji domain-containing protein 1A promotes cell growth and progression via transactivation of c-Myc expression and predicts a poor prognosis in cervical cancer

https://doi.org/10.18632/oncotarget.13208

Jue Liu, Ming Zhu, Xue Xia, Yuliang Huang, Qunfeng Zhang,  and Xiaoxu Wang
85151-85162
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumor specific delivery and therapy mediate by integrin β6-target immunoliposomes for β6-siRNA in colon carcinoma

Tumor specific delivery and therapy mediate by integrin β6-target immunoliposomes for β6-siRNA in colon carcinoma

https://doi.org/10.18632/oncotarget.13209

Liu Song, Zhang Fan, Niu Jun, Liang Benjia, Li Zequn, Wang Xilong, Jia Zhongming, Han yong, Wang Xiaohong, Cheng Kai,  and Yang Zhenlin
85163-85175
Abstract  |  PDF  |  HTML  |  Order a Reprint

Folate intake and the risk of endometrial cancer: A meta-analysis

Folate intake and the risk of endometrial cancer: A meta-analysis

https://doi.org/10.18632/oncotarget.13211

Li Du, Yulong Wang, Hang Zhang, Hong Zhang,  and Ying Gao
85176-85184
Abstract  |  PDF  |  HTML  |  Order a Reprint

CXCR4 antagonists suppress small cell lung cancer progression

CXCR4 antagonists suppress small cell lung cancer progression

https://doi.org/10.18632/oncotarget.13238

Sanaz Taromi, Gian Kayser, Julie Catusse, Dominik von Elverfeldt, Wilfried Reichardt, Friederike Braun, Wolfgang A. Weber, Robert Zeiser,  and Meike Burger
85185-85195
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic significance of L1 cell adhesion molecule in cancer patients: A systematic review and meta-analysis

Prognostic significance of L1 cell adhesion molecule in cancer patients: A systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.13236

Teng Hua, Shuangge Liu, Xiaoyan Xin, Zhishan Jin, Qibin Liu, Shuqi Chi, Xiaoxiao Wang,  and Hongbo Wang
85196-85207
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sulforaphane inhibits proliferation and invasive activity of everolimus-resistant kidney cancer cells in vitro

Sulforaphane inhibits proliferation and invasive activity of everolimus-resistant kidney cancer cells in vitro

https://doi.org/10.18632/oncotarget.13421

Eva Juengel, Sebastian Maxeiner, Jochen Rutz, Saira Justin, Frederik Roos, Wael Khoder, Igor Tsaur, Karen Nelson, Wolf O. Bechstein, Axel Haferkamp,  and Roman A. Blaheta
85208-85219
Abstract  |  PDF  |  HTML  |  Order a Reprint

Laricitrin ameliorates lung cancer-mediated dendritic cell suppression by inhibiting signal transducer and activator of transcription 3

Laricitrin ameliorates lung cancer-mediated dendritic cell suppression by inhibiting signal transducer and activator of transcription 3

https://doi.org/10.18632/oncotarget.13240

Wei-An Chang, Jen-Yu Hung, Shu-Fang Jian, Yi-Shiuan Lin, Cheng-Ying Wu, Ya-Ling Hsu,  and Po-Lin Kuo
85220-85234
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic and predictive values of CDK1 and MAD2L1 in lung adenocarcinoma

Prognostic and predictive values of CDK1 and MAD2L1 in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.13252

Yuan-Xiang Shi, Tao Zhu, Ting Zou, Wei Zhuo, Yi-Xin Chen, Ma-Sha Huang, Wei Zheng, Chen-Jing Wang, Xi Li, Xiao-Yuan Mao, Wei Zhang, Hong-Hao Zhou, Ji-Ye Yin,  and Zhao-Qian Liu
85235-85243
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression of ATPase Na+/K+ transporting alpha 1 polypeptide, ATP1A1, correlates with clinical diagnosis and progression of esophageal squamous cell carcinoma

Overexpression of ATPase Na+/K+ transporting alpha 1 polypeptide, ATP1A1, correlates with clinical diagnosis and progression of esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.13267

I-Chen Wu, Yu-Kuei Chen, Chun-Chieh Wu, Yu-Jen Cheng, Wei-Chung Chen, Huey-Jiun Ko, Yu-Peng Liu, Chee-Yin Chai, Hung-Shun Lin, Deng-Chyang Wu,  and Ming-Tsang Wu
85244-85258
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ribosomal protein L34 promotes the proliferation, invasion and metastasis of pancreatic cancer cells

Ribosomal protein L34 promotes the proliferation, invasion and metastasis of pancreatic cancer cells

https://doi.org/10.18632/oncotarget.13269

Feng Wei, Lijuan Ding, Zhentong Wei, Yandong Zhang, Yang Li, Luo Qinghua, Yuteng Ma, Liang Guo, Guoyue Lv,  and Yan Liu
85259-85272
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumor-targeting adenovirus OBP-401 inhibits primary and metastatic tumor growth of triple-negative breast cancer in orthotopic nude-mouse models

Tumor-targeting adenovirus OBP-401 inhibits primary and metastatic tumor growth of triple-negative breast cancer in orthotopic nude-mouse models

https://doi.org/10.18632/oncotarget.13296

Shuya Yano, Kiyoto Takehara, Hiroyuki Kishimoto, Hiroshi Tazawa, Yasuo Urata, Shunsuke Kagawa, Michael Bouvet, Toshiyoshi Fujiwara,  and Robert M. Hoffman
85273-85282
Abstract  |  PDF  |  HTML  |  Order a Reprint

The relationship between polymorphisms of XRCC5 genes with astrocytoma prognosis in the Han Chinese population

The relationship between polymorphisms of XRCC5 genes with astrocytoma prognosis in the Han Chinese population

https://doi.org/10.18632/oncotarget.13297

Xue He, Xikai Zhu, Lei Li, Jiayi Zhang, Ruipeng Wu, Yuan Zhang, Longli Kang, Dongya Yuan,  and Tianbo Jin
85283-85290
Abstract  |  PDF  |  HTML  |  Order a Reprint

Thrombin inhibition and cisplatin block tumor progression in ovarian cancer by alleviating the immunosuppressive microenvironment

Thrombin inhibition and cisplatin block tumor progression in ovarian cancer by alleviating the immunosuppressive microenvironment

https://doi.org/10.18632/oncotarget.13300

Eric T. Alexander, Allyson R. Minton, Molly C. Peters, Joanne Van Ryn,  and Susan K. Gilmour
85291-85305
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sunitinib for the treatment of benign and malignant neoplasms from von Hippel-Lindau disease: A single-arm, prospective phase II clinical study from the PREDIR group

Sunitinib for the treatment of benign and malignant neoplasms from von Hippel-Lindau disease: A single-arm, prospective phase II clinical study from the PREDIR group

https://doi.org/10.18632/oncotarget.13301

Stéphane Oudard, Reza Elaidi, Mara Brizard, Céline Le Rest, Valérie Caillet, Sophie Deveaux, Gérard Benoit, Jean-Michel Corréas, Farida Benoudiba, Philippe David, Alain Gaudric, Pascal Hammel, Dominique Joly, Marc Olivier Timsit, Arnaud Méjean,  and Stéphane Richard
85306-85317
Abstract  |  PDF  |  HTML  |  Order a Reprint

Isoliquiritigenin decreases the incidence of colitis-associated colorectal cancer by modulating the intestinal microbiota

Isoliquiritigenin decreases the incidence of colitis-associated colorectal cancer by modulating the intestinal microbiota

https://doi.org/10.18632/oncotarget.13347

Minna Wu, Yaqi Wu, Baoguo Deng, Jinsong Li, Haiying Cao, Yan Qu, Xinlai Qian,  and Genshen Zhong
85318-85331
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Kallikrein-related peptidase 6 induces chemotherapeutic resistance by attenuating auranofin-induced cell death through activation of autophagy in gastric cancer

Kallikrein-related peptidase 6 induces chemotherapeutic resistance by attenuating auranofin-induced cell death through activation of autophagy in gastric cancer

https://doi.org/10.18632/oncotarget.13352

Tae Woo Kim, Seon-Jin Lee, Jong-Tae Kim, Sun Jung Kim, Jeong-Ki Min, Kwang-Hee Bae, Haiyoung Jung, Bo-Yeon Kim, Jong-Seok Lim, Young Yang, Do-Young Yoon, Yong-Kyung Choe,  and Hee Gu Lee
85332-85348
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Enumeration and targeted analysis of KRAS, BRAF and PIK3CA mutations in CTCs captured by a label-free platform: Comparison to ctDNA and tissue in metastatic colorectal cancer

Enumeration and targeted analysis of KRAS, BRAF and PIK3CA mutations in CTCs captured by a label-free platform: Comparison to ctDNA and tissue in metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.13350

Evelyn Kidess-Sigal, Haiyan E. Liu, Melanie M. Triboulet, James Che, Vishnu C. Ramani, Brendan C. Visser, George A. Poultsides, Teri A. Longacre, Andre Marziali, Valentina Vysotskaia, Matthew Wiggin, Kyra Heirich, Violet Hanft, Ulrich Keilholz, Ingeborg Tinhofer, Jeffrey A. Norton, Mark Lee, Elodie Sollier-Christen,  and Stefanie S. Jeffrey
85349-85364
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress

TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress

https://doi.org/10.18632/oncotarget.13378

Govind M. Pai, Alexandra Zielinski, Dennis Koalick, Kristin Ludwig, Zhao-Qi Wang, Kerstin Borgmann, Helmut Pospiech,  and Ignacio Rubio
85365-85380
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pin1 induces the ADP-induced migration of human dental pulp cells through P2Y1 stabilization

Pin1 induces the ADP-induced migration of human dental pulp cells through P2Y1 stabilization

https://doi.org/10.18632/oncotarget.13377

Soo-A Kim, Hong Seok Choi,  and Sang-Gun Ahn
85381-85392
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

YWHAE silencing induces cell proliferation, invasion and migration through the up-regulation of CDC25B and MYC in gastric cancer cells: new insights about YWHAE role in the tumor development and metastasis process

YWHAE silencing induces cell proliferation, invasion and migration through the up-regulation of CDC25B and MYC in gastric cancer cells: new insights about YWHAE role in the tumor development and metastasis process

https://doi.org/10.18632/oncotarget.13381

Mariana Ferreira Leal, Helem Ferreira Ribeiro, Juan Antonio Rey, Giovanny Rebouças Pinto, Marília Cardoso Smith, Caroline Aquino Moreira-Nunes, Paulo Pimentel Assumpção, Leticia Martins Lamarão, Danielle Queiroz Calcagno, Raquel Carvalho Montenegro,  and Rommel Rodriguez Burbano
85393-85410
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of an HSP90 modulated multi-step process for ERBB2 degradation in breast cancer cells

Identification of an HSP90 modulated multi-step process for ERBB2 degradation in breast cancer cells

https://doi.org/10.18632/oncotarget.13392

Patrizio Castagnola, Grazia Bellese, Filippo Birocchi, Maria Cristina Gagliani, Carlo Tacchetti,  and Katia Cortese
85411-85429
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Quantification of tumor-derived cell free DNA(cfDNA) by digital PCR (DigPCR) in cerebrospinal fluid of patients with BRAFV600 mutated malignancies

Quantification of tumor-derived cell free DNA(cfDNA) by digital PCR (DigPCR) in cerebrospinal fluid of patients with BRAFV600 mutated malignancies

https://doi.org/10.18632/oncotarget.13397

Parisa Momtaz, Elena Pentsova, Omar Abdel-Wahab, Eli Diamond, David Hyman, T. Merghoub, Daoqi You, Billel Gasmi, Agnes Viale,  and Paul B. Chapman
85430-85436
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cancer cell CCL5 mediates bone marrow independent angiogenesis in breast cancer

Cancer cell CCL5 mediates bone marrow independent angiogenesis in breast cancer

https://doi.org/10.18632/oncotarget.13387

Michael John Sax, Christin Gasch, Vineel Rag Athota, Ruth Freeman, Parisa Rasighaemi, David Elton Westcott, Christopher John Day, Iva Nikolic, Benjamin Elsworth, Ming Wei, Kelly Rogers, Alexander Swarbrick, Vivek Mittal, Normand Pouliot,  and Albert Sleiman Mellick
85437-85449
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sorafenib pretreatment enhances radiotherapy through targeting MEK/ERK/NF-κB pathway in human hepatocellular carcinoma-bearing mouse model

Sorafenib pretreatment enhances radiotherapy through targeting MEK/ERK/NF-κB pathway in human hepatocellular carcinoma-bearing mouse model

https://doi.org/10.18632/oncotarget.13398

John Chun-Hao Chen, Hui-Yen Chuang, Fei-Ting Hsu, Yi-Chen Chen, Yi-Chun Chien,  and Jeng-Jong Hwang
85450-85463
Abstract  |  PDF  |  HTML  |  Order a Reprint

Impact of diabetes-related gene polymorphisms on the clinical characteristics of type 2 diabetes Chinese Han population

Impact of diabetes-related gene polymorphisms on the clinical characteristics of type 2 diabetes Chinese Han population

https://doi.org/10.18632/oncotarget.13399

Jing Li, Jiachen Wei, Pengcheng Xu, Mengdan Yan, Jingjie Li, Zhengshuai Chen,  and Tianbo Jin
85464-85471
Abstract  |  PDF  |  HTML  |  Order a Reprint

Diisononyl phthalate aggravates allergic dermatitis by activation of NF-kB

Diisononyl phthalate aggravates allergic dermatitis by activation of NF-kB

https://doi.org/10.18632/oncotarget.13403

Jun Kang, Jing Song, Shiping Shen, Baizhan Li, Xu Yang,  and Mingqing Chen
85472-85482
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association of multiple genetic variants with breast cancer susceptibility in the Han Chinese population

Association of multiple genetic variants with breast cancer susceptibility in the Han Chinese population

https://doi.org/10.18632/oncotarget.13402

Xu Li, Wenjing Zou, Ming Liu, Wei Cao, Yonghong Jiang, Gaili An, Yuzheng Wang, Shangke Huang,  and Xinhan Zhao
85483-85491
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Synergistic antitumor activity of the combination of salubrinal and rapamycin against human cholangiocarcinoma cells

Synergistic antitumor activity of the combination of salubrinal and rapamycin against human cholangiocarcinoma cells

https://doi.org/10.18632/oncotarget.13408

Xiaofang Zhao, Chunyan Zhang, Hong Zhou, Bin Xiao, Ying Cheng, Jinju Wang, Fuli Yao, Chunyan Duan, Run Chen, Youping Liu, Chunhong Feng, Hong Li, Jing Li,  and Rongyang Dai
85492-85501
Abstract  |  PDF  |  HTML  |  Order a Reprint

Expression analysis and clinical significance of eIF4E, VEGF-C, E-cadherin and MMP-2 in colorectal adenocarcinoma

Expression analysis and clinical significance of eIF4E, VEGF-C, E-cadherin and MMP-2 in colorectal adenocarcinoma

https://doi.org/10.18632/oncotarget.13453

Minna Gao, Xiong Zhang, Dan Li, Ping He, Wenguang Tian,  and Bo Zeng
85502-85514
Abstract  |  PDF  |  HTML  |  Order a Reprint

Low dose triptolide reverses chemoresistance in adult acute lymphoblastic leukemia cells via reactive oxygen species generation and DNA damage response disruption

Low dose triptolide reverses chemoresistance in adult acute lymphoblastic leukemia cells via reactive oxygen species generation and DNA damage response disruption

https://doi.org/10.18632/oncotarget.13454

Haijun Zhao, Pengcheng Shi, Manman Deng, Zhiwu Jiang, Yin Li, Vinodh Kannappan, Weiguang Wang, Peng Li,  and Bing Xu
85515-85528
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prevalence and clinical significance of BRCA1/2 germline and somatic mutations in Taiwanese patients with ovarian cancer

Prevalence and clinical significance of BRCA1/2 germline and somatic mutations in Taiwanese patients with ovarian cancer

https://doi.org/10.18632/oncotarget.13456

Angel Chao, Ting-Chang Chang, Nina Lapke, Shih-Ming Jung, Peter Chi, Chien-Hung Chen, Lan-Yan Yang, Cheng-Tao Lin, Huei-Jean Huang, Hung-Hsueh Chou, Jui-Der Liou, Shu-Jen Chen, Tzu-Hao Wang,  and Chyong-Huey Lai
85529-85541
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

EGFR kinase inhibitors and gastric acid suppressants in EGFR-mutant NSCLC: a retrospective database analysis of potential drug interaction

EGFR kinase inhibitors and gastric acid suppressants in EGFR-mutant NSCLC: a retrospective database analysis of potential drug interaction

https://doi.org/10.18632/oncotarget.13458

Nesaretnam Barr Kumarakulasinghe, Nicholas Syn, Yu Yang Soon, Atasha Asmat, Huili Zheng, En Yun Loy, Brendan Pang,  and Ross Andrew Soo
85542-85550
Abstract  |  PDF  |  HTML  |  Order a Reprint

Exosomal long noncoding RNA CRNDE-h as a novel serum-based biomarker for diagnosis and prognosis of colorectal cancer

Exosomal long noncoding RNA CRNDE-h as a novel serum-based biomarker for diagnosis and prognosis of colorectal cancer

https://doi.org/10.18632/oncotarget.13465

Tong Liu, Xin Zhang, Shanyu Gao, Fangmiao Jing, Yongmei Yang, Lutao Du, Guixi Zheng, Peilong Li, Chen Li,  and Chuanxin Wang
85551-85563
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Negative regulation of REST on NR2B in spinal cord contributes to the development of bone cancer pain in mice

Negative regulation of REST on NR2B in spinal cord contributes to the development of bone cancer pain in mice

https://doi.org/10.18632/oncotarget.9447

Dan Wang,  and Jianbo Yu
85564-85572
Abstract  |  PDF  |  HTML  |  Order a Reprint

Bendamustine for the treatment of relapsed or refractory peripheral T cell lymphomas: A French retrospective multicenter study

Bendamustine for the treatment of relapsed or refractory peripheral T cell lymphomas: A French retrospective multicenter study

https://doi.org/10.18632/oncotarget.10764

Emilie Reboursiere, Fabien Le Bras, Charles Herbaux, Emmanuel Gyan, Aline Clavert, Franck Morschhauser, Sandra Malak, David Sibon, Florence Broussais, Thorsten Braun, Luc-Matthieu Fornecker, Reda Garidi, Sabine Tricot, Roch Houot, Bertrand Joly, Wajed Abarah, Bachra Choufi, Anne-Dominique Pham, Anne-Claire Gac, Christophe Fruchart, Emilie Marin, Violaine Safar, Anne Parcelier, Hervé Maisonneuve, Emmanuel Bachy, Guillaume Cartron, Arnaud Jaccard, Olivier Tournilhac, Cédric Rossi, Luciane Schirmer, Jean-Alain Martignoles, Philippe Gaulard, Hervé Tilly, Gandhi Damaj,  and From the Lymphoma Study Association (LYSA) centers
85573-85583
Abstract  |  PDF  |  HTML  |  Order a Reprint

Phase II trial of concurrent chemoradiotherapy with L-asparaginase and MIDLE chemotherapy for newly diagnosed stage I/II extranodal NK/T-cell lymphoma, nasal type (CISL-1008)

Phase II trial of concurrent chemoradiotherapy with L-asparaginase and MIDLE chemotherapy for newly diagnosed stage I/II extranodal NK/T-cell lymphoma, nasal type (CISL-1008)

https://doi.org/10.18632/oncotarget.11319

Dok Hyun Yoon, Seok Jin Kim, Seong Hyun Jeong, Dong-Yeop Shin, Sung Hwa Bae, Junshik Hong, Seong Kyu Park, Ho-Young Yhim, Deok-Hwan Yang, Hyewon Lee, Hye Jin Kang, Mark Hong Lee, Hyeon-Seok Eom, Jae-Yong Kwak, Jae Hoon Lee, Cheolwon Suh,  and Won Seog Kim
85584-85591
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Low-dose green tea intake reduces incidence of atrial fibrillation in a Chinese population

Low-dose green tea intake reduces incidence of atrial fibrillation in a Chinese population

https://doi.org/10.18632/oncotarget.12243

Dong-Chen Liu, Jian-Jun Yan, You-Nan Wang, Ze-Mu Wang, Zhi-Yong Xie, Yao Ma, Yang Yang, Li Yang,  and Lian-Sheng Wang
85592-85602
Abstract  |  PDF  |  HTML  |  Order a Reprint

Is chronic hepatitis B infection a protective factor for the progression of advanced pancreatic ductal adenocarcinoma? An analysis from a large multicenter cohort study

Is chronic hepatitis B infection a protective factor for the progression of advanced pancreatic ductal adenocarcinoma? An analysis from a large multicenter cohort study

https://doi.org/10.18632/oncotarget.13000

Qiwen Chen, Zhouyu Ning, Lei Wang, Haifeng Ying, Shu Dong, Chenyue Zhang, Xiaoheng Shen, Yuanbiao Guo, Hao Chen, Xiaoyan Zhu, Yehua Shen, Weidong Shi, Yongqiang Hua, Kun Wang, Junhua Lin, Litao Xu, Lianyu Chen, Lanyun Feng, Xiumei Zhang, Jing Xie, Bo Sun, Yaqin Sun, Wenchao Gu, Mei Kang, Zheng Tang, Zhujun Chen, Zhen Chen, Luming Liu, Jinming Yu, Zhaoshen Li,  and Zhiqiang Meng
85603-85612
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

Which statistical significance test best detects oncomiRNAs in cancer tissues? An exploratory analysis

Which statistical significance test best detects oncomiRNAs in cancer tissues? An exploratory analysis

https://doi.org/10.18632/oncotarget.12828

Wei Tang, Zhijun Liao,  and Quan Zou
85613-85623
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epigenetic regulation of cancer biology and anti-tumor immunity by EZH2

Epigenetic regulation of cancer biology and anti-tumor immunity by EZH2

https://doi.org/10.18632/oncotarget.12928

Anthos Christofides, Theodoros Karantanos, Kankana Bardhan,  and Vassiliki A. Boussiotis
85624-85640
Abstract  |  PDF  |  HTML  |  Order a Reprint

Role of DNA repair machinery and p53 in the testicular germ cell cancer: a review

Role of DNA repair machinery and p53 in the testicular germ cell cancer: a review

https://doi.org/10.18632/oncotarget.13063

Francesco Jacopo Romano, Sabrina Rossetti, Vincenza Conteduca, Giuseppe Schepisi, Carla Cavaliere, Rossella Di Franco, Elvira La Mantia, Luigi Castaldo, Flavia Nocerino, Gianluca Ametrano, Francesca Cappuccio, Gabriella Malzone, Micaela Montanari, Daniela Vanacore, Vincenzo Quagliariello, Raffaele Piscitelli, Maria Filomena Pepe, Massimiliano Berretta, Carmine D’Aniello, Sisto Perdonà, Paolo Muto, Gerardo Botti, Gennaro Ciliberto, Bianca Maria Veneziani, Francesco De Falco, Piera Maiolino, Michele Caraglia, Maurizio Montella, Ugo De Giorgi,  and Gaetano Facchini
85641-85649
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNAs for osteosarcoma in the mouse: a meta-analysis

MicroRNAs for osteosarcoma in the mouse: a meta-analysis

https://doi.org/10.18632/oncotarget.13333

Junli Chang, Min Yao, Yimian Li, Dongfeng Zhao, Shaopu Hu, Xuejun Cui, Gang Liu, Qi Shi, Yongjun Wang,  and Yanping Yang
85650-85674
Abstract  |  PDF  |  HTML  |  Order a Reprint

Retraction

Retraction note: Triptolide contributes to decrease in TLR4 expression by upregulating miR-224-3p to inhibit the inflammatory reaction in diabetic nephropathy

Retraction note: Triptolide contributes to decrease in TLR4 expression by upregulating miR-224-3p to inhibit the inflammatory reaction in diabetic nephropathy

https://doi.org/10.18632/oncotarget.14017

Bei Sun, Shaolan Hu, Yongmei Li, Endong Zhu, Li Li, Fei Han, Chun-Jun Li,  and Liming Chen
85675-85675
Retraction  |  PDF


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