Oncotarget

Vol 7, No 50

December 13, 2016

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About The Cover

The cover for issue 50 of Oncotarget features Figure 6, 'Heat map showing expression profile of MCF10A cells expressing LINC00520,' from Henry, et al.

Table of Contents

Editorial

Which TDP-43 aggregates are toxic in ALS?

Which TDP-43 aggregates are toxic in ALS?

https://doi.org/10.18632/oncotarget.13461

Cristiana Valle,  and Maria Teresa Carrì
81973-81974
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NRP1 and synapse formation

NRP1 and synapse formation

https://doi.org/10.18632/oncotarget.13462

Fabrice Ango
81975-81976
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Nicotine inside neurons

Nicotine inside neurons

https://doi.org/10.18632/oncotarget.13463

Cecilia Gotti,  and Michele Zoli
81977-81978
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Editorial: Neuroscience

Galectin-1 in myelin repair

Galectin-1 in myelin repair

https://doi.org/10.18632/oncotarget.13455

Mariana Rinaldi, Laura Thomas,  and Laura A. Pasquini
81979-81980
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Priority Research Papers

LINC00520 is induced by Src, STAT3, and PI3K and plays a functional role in breast cancer

LINC00520 is induced by Src, STAT3, and PI3K and plays a functional role in breast cancer

https://doi.org/10.18632/oncotarget.11962

Whitney S. Henry, David G. Hendrickson, Francisco Beca, Benjamin Glass, Marianne Lindahl-Allen, Lizhi He, Zhe Ji, Kevin Struhl, Andrew H. Beck, John L. Rinn,  and Alex Toker
81981-81994
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Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells

Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells

https://doi.org/10.18632/oncotarget.13226

Lindsay C. Spender, G. John Ferguson, Sijia Liu, Chao Cui, Maria Romina Girotti, Gary Sibbet, Ellen B. Higgs, Morven K. Shuttleworth, Tom Hamilton, Paul Lorigan, Michael Weller, David F. Vincent, Owen J. Sansom, Margaret Frame, Peter ten Dijke, Richard Marais,  and Gareth J. Inman
81995-82012
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Transcriptomic-metabolomic reprogramming in EGFR-mutant NSCLC early adaptive drug escape linking TGFβ2-bioenergetics-mitochondrial priming

Transcriptomic-metabolomic reprogramming in EGFR-mutant NSCLC early adaptive drug escape linking TGFβ2-bioenergetics-mitochondrial priming

https://doi.org/10.18632/oncotarget.13307

Praveena S. Thiagarajan, Xiaoliang Wu, Wei Zhang, Ivy Shi, Rakesh Bagai, Patrick Leahy, Yan Feng, Martina Veigl, Daniel Lindner, David Danielpour, Lihong Yin, Rafael Rosell, Trever G. Bivona, Zhenfeng Zhang,  and Patrick C. Ma
82013-82027
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Prognostic relevance of miRNA-155 methylation in anaplastic glioma

Prognostic relevance of miRNA-155 methylation in anaplastic glioma

https://doi.org/10.18632/oncotarget.13452

Maximilian Georg Schliesser, Rainer Claus, Thomas Hielscher, Christiane Grimm, Dieter Weichenhan, Jonas Blaes, Benedikt Wiestler, Peter Hau, Johannes Schramm, Felix Sahm, Elisa K. Weiß, Markus Weiler, Constance Baer, Friederike Schmidt-Graf, Gabriele Schackert, Manfred Westphal, Anne Hertenstein, Patrick Roth, Norbert Galldiks, Christian Hartmann, Torsten Pietsch, Joerg Felsberg, Guido Reifenberger, Michael Christoph Sabel, Frank Winkler, Andreas von Deimling, Christoph Meisner, Peter Vajkoczy, Michael Platten, Michael Weller, Christoph Plass,  and Wolfgang Wick
82028-82045
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Research Papers: Gerotarget (Focus on Aging)

CDKN2BAS polymorphisms are associated with coronary heart disease risk a Han Chinese population

CDKN2BAS polymorphisms are associated with coronary heart disease risk a Han Chinese population

https://doi.org/10.18632/oncotarget.12575

Qingbin Zhao, Shudan Liao, Huiyi Wei, Dandan Liu, Jingjie Li, Xiyang Zhang, Mengdan Yan,  and Tianbo Jin
82046-82054
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Abdominal adipose tissue thickness measured using magnetic resonance imaging is associated with lumbar disc degeneration in a Chinese patient population

Abdominal adipose tissue thickness measured using magnetic resonance imaging is associated with lumbar disc degeneration in a Chinese patient population

https://doi.org/10.18632/oncotarget.13255

Lili Yang, Liangshan Mu, Kaiyu Huang, Tianyi Zhang, Zihan Mei, Wenrong Zeng, Jiawei He, Wei Chen, Xiaozheng Liu, Xinjian Ye,  and Zhihan Yan
82055-82062
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Research Papers: Pathology

Identification of potential genes for human ischemic cardiomyopathy based on RNA-Seq data

Identification of potential genes for human ischemic cardiomyopathy based on RNA-Seq data

https://doi.org/10.18632/oncotarget.13331

Wan Li, Liansheng Li, Shiying Zhang, Ce Zhang, Hao Huang, Yiran Li, Erqiang Hu, Gun Deng, Shanshan Guo, Yahui Wang, Weimin Li,  and Lina Chen
82063-82073
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Differences in reproductive toxicology between alopecia drugs: an analysis on adverse events among female and male cases

Differences in reproductive toxicology between alopecia drugs: an analysis on adverse events among female and male cases

https://doi.org/10.18632/oncotarget.12617

Min Wu, Qingxiong Yu,  and Qingfeng Li
82074-82084
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Resveratrol changes spermatogonial stem cells (SSCs) activity and ameliorates their loss in busulfan-induced infertile mouse

Resveratrol changes spermatogonial stem cells (SSCs) activity and ameliorates their loss in busulfan-induced infertile mouse

https://doi.org/10.18632/oncotarget.12990

Chongyang Wu, Ying Zhang, Qiaoyan Shen, Zhe Zhou, Weishuai Liu,  and Jinlian Hua
82085-82096
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Multipoint Kras oncogene mutations potentially indicate mucinous carcinoma on the entire spectrum of mucinous ovarian neoplasms

Multipoint Kras oncogene mutations potentially indicate mucinous carcinoma on the entire spectrum of mucinous ovarian neoplasms

https://doi.org/10.18632/oncotarget.13449

Yi-Ju Lee, Ming-Yung Lee, Alexandra Ruan, Chi-Kuan Chen, Hao-Ping Liu, Chau-Jong Wang, Wan-Ru Chao,  and Chih-Ping Han
82097-82103
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KIR 2D (L1, L3, L4, S4) and KIR 3DL1 protein expression in non-small cell lung cancer

KIR 2D (L1, L3, L4, S4) and KIR 3DL1 protein expression in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.13486

Yayi He, Paul A. Bunn, Caicun Zhou,  and Dan Chan
82104-82111
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Research Papers: Immunology

Complex dissemination of the diversified mcr-1-harbouring plasmids in Escherichia coli of different sequence types

Complex dissemination of the diversified mcr-1-harbouring plasmids in Escherichia coli of different sequence types

https://doi.org/10.18632/oncotarget.12621

Qingjing Wang, Zhencui Li, Jingxia Lin, Xiuna Wang, Xianbo Deng,  and Youjun Feng
82112-82122
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Pentraxin 3 plasma levels at graft-versus-host disease onset predict disease severity and response to therapy in children given haematopoietic stem cell transplantation

Pentraxin 3 plasma levels at graft-versus-host disease onset predict disease severity and response to therapy in children given haematopoietic stem cell transplantation

https://doi.org/10.18632/oncotarget.13488

Erica Dander, Paola De Lorenzo, Barbara Bottazzi, Paola Quarello, Paola Vinci, Adriana Balduzzi, Francesca Masciocchi, Sonia Bonanomi, Claudia Cappuzzello, Giulia Prunotto, Fabio Pavan, Fabio Pasqualini, Marina Sironi, Ivan Cuccovillo, Roberto Leone, Giovanni Salvatori, Matteo Parma, Elisabetta Terruzzi, Fabio Pagni, Franco Locatelli, Alberto Mantovani, Franca Fagioli, Andrea Biondi, Cecilia Garlanda, Maria Grazia Valsecchi, Attilio Rovelli,  and Giovanna D’Amico
82123-82138
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Research Papers

YBX1 regulates tumor growth via CDC25a pathway in human lung adenocarcinoma

YBX1 regulates tumor growth via CDC25a pathway in human lung adenocarcinoma

https://doi.org/10.18632/oncotarget.10080

Shilei Zhao, Yan Wang, Tao Guo, Wendan Yu, Jinxiu Li, Zhipeng Tang, Zhenlong Yu, Lei Zhao, Yixiang Zhang, Ziyi Wang, Peng Wang, Yechi Li, Fengzhou Li, Zhe Sun, Yang Xuan, Ranran Tang, Wu-guo Deng, Wei Guo,  and Chundong Gu
82139-82157
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Pattern of RECK CpG methylation as a potential marker for predicting breast cancer prognosis and drug-sensitivity

Pattern of RECK CpG methylation as a potential marker for predicting breast cancer prognosis and drug-sensitivity

https://doi.org/10.18632/oncotarget.8620

Gongping Shi, Yoko Yoshida, Kanako Yuki, Tomomi Nishimura, Yukiko Kawata, Masahiro Kawashima, Keiko Iwaisako, Kiyotsugu Yoshikawa, Junichi Kurebayashi, Masakazu Toi,  and Makoto Noda
82158-82169
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Multifunctional near-infrared light-triggered biodegradable micelles for chemo- and photo-thermal combination therapy

Multifunctional near-infrared light-triggered biodegradable micelles for chemo- and photo-thermal combination therapy

https://doi.org/10.18632/oncotarget.10320

Jie Cao, Dan Chen, Shanshan Huang, Dawei Deng, Liping Tang,  and Yueqing Gu
82170-82184
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Synthetic lethal interaction of cetuximab with MEK1/2 inhibition in NRAS-mutant metastatic colorectal cancer

Synthetic lethal interaction of cetuximab with MEK1/2 inhibition in NRAS-mutant metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.11985

Bernardo Queralt, Elisabet Cuyàs, Joaquim Bosch-Barrera, Anna Massaguer, Rafael de Llorens, Begoña Martin-Castillo, Joan Brunet, Ramon Salazar,  and Javier A. Menendez
82185-82199
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Effective elimination of adult B-lineage acute lymphoblastic leukemia by disulfiram/copper complex in vitro and in vivo in patient-derived xenograft models

Effective elimination of adult B-lineage acute lymphoblastic leukemia by disulfiram/copper complex in vitro and in vivo in patient-derived xenograft models

https://doi.org/10.18632/oncotarget.9413

Manman Deng, Zhiwu Jiang, Yin Li, Yong Zhou, Jie Li, Xiangmeng Wang, Yao Yao, Weiguang Wang, Peng Li,  and Bing Xu
82200-82212
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epstein-Barr virus BARF1-induced NFκB/miR-146a/SMAD4 alterations in stomach cancer cells

Epstein-Barr virus BARF1-induced NFκB/miR-146a/SMAD4 alterations in stomach cancer cells

https://doi.org/10.18632/oncotarget.10511

Dong Ha Kim, Mee Soo Chang, Chan Jin Yoon, Jaap M. Middeldorp, Olivia M. Martinez, Sun-ju Byeon, Sun Young Rha, Sung Han Kim, Yang Soo Kim,  and Jun Hee Woo
82213-82227
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SOX9 is an atypical intestinal tumor suppressor controlling the oncogenic Wnt/ß-catenin signaling

SOX9 is an atypical intestinal tumor suppressor controlling the oncogenic Wnt/ß-catenin signaling

https://doi.org/10.18632/oncotarget.10573

Corinne Prévostel, Cyrine Rammah-Bouazza, Hélène Trauchessec, Lucile Canterel-Thouennon, Muriel Busson, Marc Ychou,  and Philippe Blache
82228-82243
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Charcot-Marie-Tooth gene, SBF2, associated with taxane-induced peripheral neuropathy in African Americans

Charcot-Marie-Tooth gene, SBF2, associated with taxane-induced peripheral neuropathy in African Americans

https://doi.org/10.18632/oncotarget.12545

Bryan P. Schneider, Dongbing Lai, Fei Shen, Guanglong Jiang, Milan Radovich, Lang Li, Laura Gardner, Kathy D. Miller, Anne O’Neill, Joseph A. Sparano, Gloria Xue, Tatiana Foroud,  and George W. Sledge Jr.
82244-82253
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Early2 factor (E2F) deregulation is a prognostic and predictive biomarker in lung adenocarcinoma

Early2 factor (E2F) deregulation is a prognostic and predictive biomarker in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.12672

Lu Chen, Courtney A. Kurtyka, Eric A. Welsh, Jason I. Rivera, Brienne E. Engel, Teresita Muñoz-Antonia, Sean J. Yoder, Steven A. Eschrich, Ben C. Creelan, Alberto A. Chiappori, Jhanelle E. Gray, Jose Luis Ramirez, Rafael Rosell, Matthew B. Schabath, Eric B. Haura, Dung-Tsa Chen,  and W. Douglas Cress
82254-82265
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Positive associations between galectin-3 and PSA levels in prostate cancer patients: a prospective clinical study-I

Positive associations between galectin-3 and PSA levels in prostate cancer patients: a prospective clinical study-I

https://doi.org/10.18632/oncotarget.12619

Kosei Nakajima, Lance K. Heilbrun, Victor Hogan, Daryn Smith, Elisabeth Heath,  and Avraham Raz
82266-82272
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c-Myc deregulation induces mRNA capping enzyme dependency

c-Myc deregulation induces mRNA capping enzyme dependency

https://doi.org/10.18632/oncotarget.12701

Olivia Lombardi, Dhaval Varshney, Nicola M. Phillips,  and Victoria H. Cowling
82273-82288
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Serpin E2 promotes breast cancer metastasis by remodeling the tumor matrix and polarizing tumor associated macrophages

Serpin E2 promotes breast cancer metastasis by remodeling the tumor matrix and polarizing tumor associated macrophages

https://doi.org/10.18632/oncotarget.12927

Tatiana Smirnova, Laura Bonapace, Gwen MacDonald, Shunya Kondo, Jeffrey Wyckoff, Hilmar Ebersbach, Bérengère Fayard, Arno Doelemeyer, Marie-May Coissieux, Marinus R. Heideman, Mohamed Bentires-Alj,  and Nancy E. Hynes
82289-82304
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cranial irradiation induces transient microglia accumulation, followed by long-lasting inflammation and loss of microglia

Cranial irradiation induces transient microglia accumulation, followed by long-lasting inflammation and loss of microglia

https://doi.org/10.18632/oncotarget.12929

Wei Han, Takashi Umekawa, Kai Zhou, Xing-Mei Zhang, Makiko Ohshima, Cecilia A. Dominguez, Robert A. Harris, Changlian Zhu,  and Klas Blomgren
82305-82323
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Heterotypic paracrine signaling drives fibroblast senescence and tumor progression of large cell carcinoma of the lung

Heterotypic paracrine signaling drives fibroblast senescence and tumor progression of large cell carcinoma of the lung

https://doi.org/10.18632/oncotarget.10327

Roberto Lugo, Marta Gabasa, Francesca Andriani, Marta Puig, Federica Facchinetti, Josep Ramírez, Abel Gómez-Caro, Ugo Pastorino, Gemma Fuster, Isaac Almendros, Pere Gascón, Albert Davalos, Noemí Reguart, Luca Roz,  and Jordi Alcaraz
82324-82337
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-891b is an independent prognostic factor of pancreatic cancer by targeting Cbl-b to suppress the growth of pancreatic cancer cells

MicroRNA-891b is an independent prognostic factor of pancreatic cancer by targeting Cbl-b to suppress the growth of pancreatic cancer cells

https://doi.org/10.18632/oncotarget.11001

Qian Dong, Ce Li, Xiaofang Che, Jinglei Qu, Yibo Fan, Xiaohan Li, Yue Li, Qian Wang, Yunpeng Liu, Xianghong Yang,  and Xiujuan Qu
82338-82353
Abstract  |  PDF  |  HTML  |  Order a Reprint

Multiparameter comparative analysis reveals differential impacts of various cytokines on CART cell phenotype and function ex vivo and in vivo

Multiparameter comparative analysis reveals differential impacts of various cytokines on CART cell phenotype and function ex vivo and in vivo

https://doi.org/10.18632/oncotarget.10510

Xiao-Jun Xu, De-Gang Song, Mathilde Poussin, Qunrui Ye, Prannda Sharma, Alba Rodríguez-García, Yong-Min Tang,  and Daniel J. Powell
82354-82368
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Attribution of NKG2DL to the inhibition of early stage allogeneic tumors in mice

Attribution of NKG2DL to the inhibition of early stage allogeneic tumors in mice

https://doi.org/10.18632/oncotarget.10693

Li Hua, Mingli Fang, Boqi Dong, Sheng Guo, Cuiyun Cui, Jiwei Liu, Yun Yao, Yue Xiao, Xin Li, Yunjia Ren, Xiuping Meng, Xu Hao, Peiyan Zhao, Yilan Song, Liying Wang,  and Yongli Yu
82369-82383
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Associations of genotypes and haplotypes of IL-17 with risk of gastric cancer in an eastern Chinese population

Associations of genotypes and haplotypes of IL-17 with risk of gastric cancer in an eastern Chinese population

https://doi.org/10.18632/oncotarget.11616

Fei Zhou, Li-Xin Qiu, Lei Cheng, Meng-Yun Wang, Jin Li, Meng-Hong Sun, Ya-Jun Yang, Jiu-Cun Wang, Li Jin, Ya-Nong Wang,  and Qing-Yi Wei
82384-82395
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

No association between telomere length-related loci and number of cutaneous nevi

No association between telomere length-related loci and number of cutaneous nevi

https://doi.org/10.18632/oncotarget.12021

Xin Li, Geyu Liang, Mengmeng Du, Immaculata De Vivo,  and Hongmei Nan
82396-82399
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epigenetic silencing of tumor suppressor long non-coding RNA BM742401 in chronic lymphocytic leukemia

Epigenetic silencing of tumor suppressor long non-coding RNA BM742401 in chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.12252

Lu Qian Wang, Kwan Yeung Wong, Zhen Hai Li,  and Chor Sang Chim
82400-82410
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RND3 promotes Snail 1 protein degradation and inhibits glioblastoma cell migration and invasion

RND3 promotes Snail 1 protein degradation and inhibits glioblastoma cell migration and invasion

https://doi.org/10.18632/oncotarget.12396

Baohui Liu, Huimin Dong, Xi Lin, Xiangsheng Yang, Xiaojing Yue, Jian Yang, Yuntao Li, Liquan Wu, Xiaonan Zhu, Shenqi Zhang, Daofeng Tian, Junmin Wang, Qiang Cai, Shanping Mao, Qianxue Chen,  and Jiang Chang
82411-82423
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Phosphatidyl inositol-3 kinase (PIK3CA) E545K mutation confers cisplatin resistance and a migratory phenotype in cervical cancer cells

Phosphatidyl inositol-3 kinase (PIK3CA) E545K mutation confers cisplatin resistance and a migratory phenotype in cervical cancer cells

https://doi.org/10.18632/oncotarget.10955

Wani Arjumand, Cole D. Merry, Chen Wang, Elias Saba, John B. McIntyre, Shujuan Fang, Elizabeth Kornaga, Prafull Ghatage, Corinne M. Doll,  and Susan P. Lees-Miller
82424-82439
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of self-interacting proteins by exploring evolutionary information embedded in PSI-BLAST-constructed position specific scoring matrix

Identification of self-interacting proteins by exploring evolutionary information embedded in PSI-BLAST-constructed position specific scoring matrix

https://doi.org/10.18632/oncotarget.12517

Ji-Yong An, Zhu-Hong You, Xing Chen, De-Shuang Huang, Zheng-Wei Li, Gang Liu,  and Yin Wang
82440-82449
Abstract  |  PDF  |  HTML  |  Order a Reprint

ATM is the primary kinase responsible for phosphorylation of Hsp90α after ionizing radiation

ATM is the primary kinase responsible for phosphorylation of Hsp90α after ionizing radiation

https://doi.org/10.18632/oncotarget.12557

Ameer L. Elaimy, Aarif Ahsan, Katherine Marsh, William B. Pratt, Dipankar Ray, Theodore S. Lawrence,  and Mukesh K. Nyati
82450-82457
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Combinatorial effects of doxorubicin and retargeted tissue factor by intratumoral entrapment of doxorubicin and proapoptotic increase of tumor vascular infarction

Combinatorial effects of doxorubicin and retargeted tissue factor by intratumoral entrapment of doxorubicin and proapoptotic increase of tumor vascular infarction

https://doi.org/10.18632/oncotarget.12559

Janine Stucke-Ring, Julian Ronnacker, Caroline Brand, Carsten Höltke, Christoph Schliemann, Torsten Kessler, Lars Henning Schmidt, Saliha Harrach, Verena Mantke, Heike Hintelmann, Wolfgang Hartmann, Eva Wardelmann, Georg Lenz, Bernhard Wünsch, Carsten Müller-Tidow, Rolf M. Mesters, Christian Schwöppe,  and Wolfgang E. Berdel
82458-82472
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Bevacizumab and wound-healing complications: a systematic review and meta-analysis of randomized controlled trials

Bevacizumab and wound-healing complications: a systematic review and meta-analysis of randomized controlled trials

https://doi.org/10.18632/oncotarget.12666

Hongliang Zhang, Zhenguang Huang, Xiaoqin Zou,  and Taotao Liu
82473-82481
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Mesenchymal stem cells and macrophages interact through IL-6 to promote inflammatory breast cancer in pre-clinical models

Mesenchymal stem cells and macrophages interact through IL-6 to promote inflammatory breast cancer in pre-clinical models

https://doi.org/10.18632/oncotarget.12694

Adam R. Wolfe, Nicholaus J Trenton, Bisrat G. Debeb, Richard Larson, Brian Ruffell, Khoi Chu, Walter Hittelman, Michael Diehl, Jim M Reuben, Naoto T. Ueno,  and Wendy A. Woodward
82482-82492
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Anti-FIRs (PUF60) auto-antibodies are detected in the sera of early-stage colon cancer patients

Anti-FIRs (PUF60) auto-antibodies are detected in the sera of early-stage colon cancer patients

https://doi.org/10.18632/oncotarget.12696

Sohei Kobayashi, Tyuji Hoshino, Takaki Hiwasa, Mamoru Satoh, Bahityar Rahmutulla, Sachio Tsuchida, Yuji Komukai, Tomoaki Tanaka, Hisahiro Matsubara, Hideaki Shimada, Fumio Nomura,  and Kazuyuki Matsushita
82493-82503
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mismatch repair deficiency may be common in ductal adenocarcinoma of the prostate

Mismatch repair deficiency may be common in ductal adenocarcinoma of the prostate

https://doi.org/10.18632/oncotarget.12697

Michael T. Schweizer, Heather H. Cheng, Maria S. Tretiakova, Funda Vakar-Lopez, Nola Klemfuss, Eric Q. Konnick, Elahe A. Mostaghel, Peter S. Nelson, Evan Y. Yu, Bruce Montgomery, Lawrence D. True,  and Colin C. Pritchard
82504-82510
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IGF-1 contributes to the expansion of melanoma-initiating cells through an epithelial-mesenchymal transition process

IGF-1 contributes to the expansion of melanoma-initiating cells through an epithelial-mesenchymal transition process

https://doi.org/10.18632/oncotarget.12733

Vincent Le Coz, Chaobin Zhu, Aurore Devocelle, Aimé Vazquez, Claude Boucheix, Sandy Azzi, Cindy Gallerne, Pierre Eid, Séverine Lecourt,  and Julien Giron-Michel
82511-82527
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Genetic polymorphisms of Wnt/β-catenin pathway genes are associated with the efficacy and toxicities of radiotherapy in patients with nasopharyngeal carcinoma

Genetic polymorphisms of Wnt/β-catenin pathway genes are associated with the efficacy and toxicities of radiotherapy in patients with nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.12754

Jingjing Yu, Yuling Huang, Lijuan Liu, Jing Wang, Jiye Yin, Lihua Huang, Shaojun Chen, Jingao Li, Hong Yuan, Guoping Yang, Wenyu Liu, Hai Wang, Qi Pei,  and Chengxian Guo
82528-82537
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The serum protein profile of early parity which induces protection against breast cancer

The serum protein profile of early parity which induces protection against breast cancer

https://doi.org/10.18632/oncotarget.12757

Christina Gutierrez Bracamontes, Rebecca Lopez-Valdez, Ramadevi Subramani, Arunkumar Arumugam, Sushmita Nandy, Venkatesh Rajamanickam, Vignesh Ravichandran,  and Rajkumar Lakshmanaswamy
82538-82553
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Babao Dan attenuates hepatic fibrosis by inhibiting hepatic stellate cells activation and proliferation via TLR4 signaling pathway

Babao Dan attenuates hepatic fibrosis by inhibiting hepatic stellate cells activation and proliferation via TLR4 signaling pathway

https://doi.org/10.18632/oncotarget.12783

Lei Liang, Xue Yang, Yang Yu, Xiaoyong Li, Yechen Wu, Rongyu Shi, Jinghua Jiang, Lu Gao, Fei Ye, Qiudong Zhao, Rong Li, Lixin Wei,  and Zhipeng Han
82554-82566
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Evaluating the efficacy and safety of intravesical chemotherapies for non-muscle invasive bladder cancer: a network meta-analysis

Evaluating the efficacy and safety of intravesical chemotherapies for non-muscle invasive bladder cancer: a network meta-analysis

https://doi.org/10.18632/oncotarget.12856

Chuanjun Zhuo, Xubin Li, Hongqing Zhuang, Shunli Tian, Hailong Cui, Ronghuan Jiang, Chuanxin Liu, Ran Tao,  and Xiaodong Lin
82567-82579
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Stimulation of the toll-like receptor 3 promotes metabolic reprogramming in head and neck carcinoma cells

Stimulation of the toll-like receptor 3 promotes metabolic reprogramming in head and neck carcinoma cells

https://doi.org/10.18632/oncotarget.12892

Mathieu Veyrat, Sylvère Durand, Marion Classe, Tanja Matijevic Glavan, Natalie Oker, Nikiforos-Ioannis Kapetanakis, Xiaojun Jiang, Aurore Gelin, Philippe Herman, Odile Casiraghi, David Zagzag, David Enot, Pierre Busson,  and Benjamin Vérillaud
82580-82593
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Idiopathic male infertility in the Han population in China is affected by polymorphism in the VDAC2 gene

Idiopathic male infertility in the Han population in China is affected by polymorphism in the VDAC2 gene

https://doi.org/10.18632/oncotarget.12993

Lianjun Pan, Daoxian Qiu, Jingyun Li, Jun Li, Pu Xu, Dan Zhao,  and Jiehua Ma
82594-82601
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Hyperin protects against LPS-induced acute kidney injury by inhibiting TLR4 and NLRP3 signaling pathways

Hyperin protects against LPS-induced acute kidney injury by inhibiting TLR4 and NLRP3 signaling pathways

https://doi.org/10.18632/oncotarget.13010

Gong Chunzhi, Li Zunfeng, Qin Chengwei, Bu Xiangmei,  and Yu Jingui
82602-82608
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Positive association of collagen type I with non-muscle invasive bladder cancer progression

Positive association of collagen type I with non-muscle invasive bladder cancer progression

https://doi.org/10.18632/oncotarget.12089

Michael Brooks, Qianxing Mo, Ross Krasnow, Philip Levy Ho, Yu-Cheng Lee, Jing Xiao, Antonina Kurtova, Seth Lerner, Gui Godoy, Weiguo Jian, Patricia Castro, Fengju Chen, David Rowley, Michael Ittmann,  and Keith Syson Chan
82609-82619
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long non-coding RNA PVT1 promotes osteosarcoma development by acting as a molecular sponge to regulate miR-195

Long non-coding RNA PVT1 promotes osteosarcoma development by acting as a molecular sponge to regulate miR-195

https://doi.org/10.18632/oncotarget.13012

Quan Zhou, Fengli Chen, Jiali Zhao, Baojun Li, Yong Liang, Wei Pan, Shaoxian Zhang, Xinhong Wang,  and Donghui Zheng
82620-82633
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Syntenin-1 is a promoter and prognostic marker of head and neck squamous cell carcinoma invasion and metastasis

Syntenin-1 is a promoter and prognostic marker of head and neck squamous cell carcinoma invasion and metastasis

https://doi.org/10.18632/oncotarget.13020

Li Cui, Siliangyu Cheng, Xiaojun Liu, Diana Messadi, Yan Yang,  and Shen Hu
82634-82647
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Hormonal receptors in lung adenocarcinoma: expression and difference in outcome by sex

Hormonal receptors in lung adenocarcinoma: expression and difference in outcome by sex

https://doi.org/10.18632/oncotarget.12244

Rossana Berardi, Francesca Morgese, Alfredo Santinelli, Azzurra Onofri, Tommasina Biscotti, Alessandro Brunelli, Miriam Caramanti, Agnese Savini, Mariagrazia De Lisa, Zelmira Ballatore, Cecilia Pompili, Michele Salati, Paola Mazzanti, Mariangela Torniai,  and Stefano Cascinu
82648-82657
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Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is independent of ASS1 promoter DNA methylation

Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is independent of ASS1 promoter DNA methylation

https://doi.org/10.18632/oncotarget.12308

Yan Long, Wen-Bin Tsai, Jeffrey T. Chang, Marcos Estecio, Medhi Wangpaichitr, Naramol Savaraj, Lynn G. Feun, Helen H.W. Chen,  and Macus Tien Kuo
82658-82670
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Integrative analysis of protein-coding and non-coding RNAs identifies clinically relevant subtypes of clear cell renal cell carcinoma

Integrative analysis of protein-coding and non-coding RNAs identifies clinically relevant subtypes of clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.12340

Zongcheng Li, Yaowen Chen, Shuofeng Hu, Jian Zhang, Jiaqi Wu, Wu Ren, Ningsheng Shao,  and Xiaomin Ying
82671-82685
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The role of transcriptional coactivator TAZ in gliomas

The role of transcriptional coactivator TAZ in gliomas

https://doi.org/10.18632/oncotarget.12625

Weijie Li, Shicai Dong, Wei Wei, Guangxiu Wang, Anling Zhang, Peiyu Pu,  and Zhifan Jia
82686-82699
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Circulating microRNAs found dysregulated in ex-exposed asbestos workers and pleural mesothelioma patients as potential new biomarkers

Circulating microRNAs found dysregulated in ex-exposed asbestos workers and pleural mesothelioma patients as potential new biomarkers

https://doi.org/10.18632/oncotarget.12408

Ilaria Bononi, Manola Comar, Andrea Puozzo, Mariarita Stendardo, Piera Boschetto, Sara Orecchia, Roberta Libener, Roberto Guaschino, Silvia Pietrobon, Manuela Ferracin, Massimo Negrini, Fernanda Martini, Massimo Bovenzi,  and Mauro Tognon
82700-82711
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A four-gene signature predicts survival in clear-cell renal-cell carcinoma

A four-gene signature predicts survival in clear-cell renal-cell carcinoma

https://doi.org/10.18632/oncotarget.12631

Jun Dai, Yuchao Lu, Jinyu Wang, Lili Yang, Yingyan Han, Ying Wang, Dan Yan, Qiurong Ruan,  and Shaogang Wang
82712-82726
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic variants in TERT are associated with risk of gastric cancer in a Chinese Han population

Genetic variants in TERT are associated with risk of gastric cancer in a Chinese Han population

https://doi.org/10.18632/oncotarget.13102

Xianglong Duan, Wei Cao, Lijie Wang, Sida Liu, Zhao Liu, Bolun Zhang, Hua Yang, Tian Feng, Jiayi Zhang, Xiyang Zhang, Yanbin Long,  and Tianbo Jin
82727-82732
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Precise ERBB2 copy number assessment in breast cancer by means of molecular inversion probe array analysis

Precise ERBB2 copy number assessment in breast cancer by means of molecular inversion probe array analysis

https://doi.org/10.18632/oncotarget.12421

Matthias Christgen, Jana L. van Luttikhuizen, Mieke Raap, Peter Braubach, Lars Schmidt, Danny Jonigk, Friedrich Feuerhake, Ulrich Lehmann, Brigitte Schlegelberger, Hans H. Kreipe,  and Doris Steinemann
82733-82740
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Is ovarian cancer a targetable disease? A systematic review and meta-analysis and genomic data investigation

Is ovarian cancer a targetable disease? A systematic review and meta-analysis and genomic data investigation

https://doi.org/10.18632/oncotarget.12633

Nicoletta Staropoli, Domenico Ciliberto, Silvia Chiellino, Francesca Caglioti, Teresa Del Giudice, Simona Gualtieri, Angela Salvino, Alessandra Strangio, Cirino Botta, Sandro Pignata, Pierfrancesco Tassone,  and Pierosandro Tagliaferri
82741-82756
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Novel MDM2 inhibitor SAR405838 (MI-773) induces p53-mediated apoptosis in neuroblastoma

Novel MDM2 inhibitor SAR405838 (MI-773) induces p53-mediated apoptosis in neuroblastoma

https://doi.org/10.18632/oncotarget.12634

Jiaxiong Lu, Shan Guan, Yanling Zhao, Yang Yu, Yongfeng Wang, Yonghua Shi, Xinfang Mao, Kristine L. Yang, Wenjing Sun, Xin Xu, Joanna S. Yi, Tianshu Yang, Jianhua Yang,  and Jed G. Nuchtern
82757-82769
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Helicobacter pylori infection related long noncoding RNA (lncRNA) AF147447 inhibits gastric cancer proliferation and invasion by targeting MUC2 and up-regulating miR-34c

Helicobacter pylori infection related long noncoding RNA (lncRNA) AF147447 inhibits gastric cancer proliferation and invasion by targeting MUC2 and up-regulating miR-34c

https://doi.org/10.18632/oncotarget.13165

Xiaoying Zhou, Han Chen, Li Zhu, Bo Hao, Weifeng Zhang, Jie Hua, Huiyuan Gu, Wujuan Jin,  and Guoxin Zhang
82770-82782
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The increased expression of fatty acid-binding protein 9 in prostate cancer and its prognostic significance

The increased expression of fatty acid-binding protein 9 in prostate cancer and its prognostic significance

https://doi.org/10.18632/oncotarget.12635

Majed Saad Al Fayi, Xiaojun Gou, Shiva S. Forootan, Waseem Al-Jameel, Zhengzheng Bao, Philip R. Rudland, Philip A. Cornford, Syed A. Hussain,  and Youqiang Ke
82783-82797
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Functional variant of the P2X7 receptor gene is associated with human papillomavirus-16 positive cervical squamous cell carcinoma

Functional variant of the P2X7 receptor gene is associated with human papillomavirus-16 positive cervical squamous cell carcinoma

https://doi.org/10.18632/oncotarget.12636

Yuh-Cheng Yang, Tzu-Yang Chang, Tze-Chien Chen, Wen-Shan Lin, Shih-Chuan Chang,  and Yann-Jinn Lee
82798-82803
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Mechanism of melanoma cells selective apoptosis induced by a photoactive NADPH analogue

Mechanism of melanoma cells selective apoptosis induced by a photoactive NADPH analogue

https://doi.org/10.18632/oncotarget.12651

Florian Rouaud, Jean-Luc Boucher, Anny Slama-Schwok,  and Stéphane Rocchi
82804-82819
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Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling

Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling

https://doi.org/10.18632/oncotarget.12652

Grace Gar-Lee Yue, Minghua Liu, Zhili Zuo, Zhili Zuo, Julia Kin-Ming Lee, Mingyue Li, Stephen Kwok-Wing Tsui, Kwok-Pui Fung, Handong Sun, Jianxin Pu,  and Clara Bik-San Lau
82820-82835
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Suppression of skin tumorigenesis in CD109-deficient mice

Suppression of skin tumorigenesis in CD109-deficient mice

https://doi.org/10.18632/oncotarget.12653

Masaki Sunagawa, Shinji Mii, Atsushi Enomoto, Takuya Kato, Yoshiki Murakumo, Yukihiro Shiraki, Naoya Asai, Masato Asai, Masato Nagino,  and Masahide Takahashi
82836-82850
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Marsdenia tenacissimae extraction (MTE) inhibits the proliferation and induces the apoptosis of human acute T cell leukemia cells through inactivating PI3K/AKT/mTOR signaling pathway via PTEN enhancement

Marsdenia tenacissimae extraction (MTE) inhibits the proliferation and induces the apoptosis of human acute T cell leukemia cells through inactivating PI3K/AKT/mTOR signaling pathway via PTEN enhancement

https://doi.org/10.18632/oncotarget.12654

Ying Wang, Bingyu Chen, Zhen Wang, Wei Zhang, Ke Hao, Yu Chen, Kaiqiang Li, Tongtong Wang, Yiwei Xie, Zhihui Huang,  and Xiangmin Tong
82851-82863
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Plumbagin protects liver against fulminant hepatic failure and chronic liver fibrosis via inhibiting inflammation and collagen production

Plumbagin protects liver against fulminant hepatic failure and chronic liver fibrosis via inhibiting inflammation and collagen production

https://doi.org/10.18632/oncotarget.12655

Huafeng Wang, Huan Zhang, Yuqing Zhang, Dan Wang, Xixi Cheng, Fengrui Yang, Qi Zhang, Zhenyi Xue, Yan Li, Lijuan Zhang, Luhong Yang, Guolin Miao, Daiqing Li, Zhiyu Guan, Yurong Da, Zhi Yao, Fei Gao, Liang Qiao, Li Kong,  and Rongxin Zhang
82864-82875
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LYN expression predicts the response to dasatinib in a subpopulation of lung adenocarcinoma patients

LYN expression predicts the response to dasatinib in a subpopulation of lung adenocarcinoma patients

https://doi.org/10.18632/oncotarget.12657

Yu Jin Kim, Sungyoul Hong, Minjung Sung, Min Jeong Park, Kyungsoo Jung, Ka-Won Noh, Doo-Yi Oh, Mi-Sook Lee, Ensel Oh, Young Kee Shin,  and Yoon-La Choi
82876-82888
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting the cancer-associated fibroblasts as a treatment in triple-negative breast cancer

Targeting the cancer-associated fibroblasts as a treatment in triple-negative breast cancer

https://doi.org/10.18632/oncotarget.12658

Ken Takai, Annie Le, Valerie M. Weaver,  and Zena Werb
82889-82901
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-like viral small RNA from porcine reproductive and respiratory syndrome virus negatively regulates viral replication by targeting the viral nonstructural protein 2

MicroRNA-like viral small RNA from porcine reproductive and respiratory syndrome virus negatively regulates viral replication by targeting the viral nonstructural protein 2

https://doi.org/10.18632/oncotarget.12703

Na Li, Yunhuan Yan, Angke Zhang, Jiming Gao, Chong Zhang, Xue Wang, Gaopeng Hou, Gaiping Zhang, Jinbu Jia, En-Min Zhou,  and Shuqi Xiao
82902-82920
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The fucosylated CD147 enhances the autophagy in epithelial ovarian cancer cells

The fucosylated CD147 enhances the autophagy in epithelial ovarian cancer cells

https://doi.org/10.18632/oncotarget.13289

Zhenhua Hu, Mingbo Cai, Lu Deng, Liancheng Zhu, Jian Gao, Mingzi Tan, Juanjuan Liu,  and Bei Lin
82921-82932
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TNFAIP3 gene rs10499194, rs13207033 polymorphisms decrease the risk of rheumatoid arthritis

TNFAIP3 gene rs10499194, rs13207033 polymorphisms decrease the risk of rheumatoid arthritis

https://doi.org/10.18632/oncotarget.12638

Ming-Jie Wang, Hao-Yu Yang, Hui Zhang, Xindie Zhou, Rui-Ping Liu,  and Yuan-Yuan Mi
82933-82942
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ALK FISH patterns and the detection of ALK fusions by next generation sequencing in lung adenocarcinoma

ALK FISH patterns and the detection of ALK fusions by next generation sequencing in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.12705

Sanja Dacic, Liza C. Villaruz, Shira Abberbock, Alyssa Mahaffey, Pimpin Incharoen,  and Marina N. Nikiforova
82943-82952
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An assessment of the benefit-risk balance of FOLFIRINOX in metastatic pancreatic adenocarcinoma

An assessment of the benefit-risk balance of FOLFIRINOX in metastatic pancreatic adenocarcinoma

https://doi.org/10.18632/oncotarget.12761

Julien Péron, Pascal Roy, Thierry Conroy, Françoise Desseigne, Marc Ychou, Sophie Gourgou-Bourgade, Trevor Stanbury, Laurent Roche, Brice Ozenne,  and Marc Buyse
82953-82960
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CDH4 suppresses the progression of salivary adenoid cystic carcinoma via E-cadherin co-expression

CDH4 suppresses the progression of salivary adenoid cystic carcinoma via E-cadherin co-expression

https://doi.org/10.18632/oncotarget.12821

Jian Xie, Yan Feng, Ting Lin, Xiao-Yu Huang, Rui-Huan Gan, Yong Zhao, Bo-Hua Su, Lin-Can Ding, Lin She, Jiang Chen, Li-Song Lin, Xu Lin, Da-Li Zheng,  and You-Guang Lu
82961-82971
Abstract  |  PDF  |  HTML  |  Order a Reprint

14-3-3ζ/TGFβR1 promotes tumor metastasis in lung squamous cell carcinoma

14-3-3ζ/TGFβR1 promotes tumor metastasis in lung squamous cell carcinoma

https://doi.org/10.18632/oncotarget.12690

Yanbin Zhao, Wenbo Qiao, Xiaoyuan Wang, Hang Yin, Jianqi Cui, Yue Cui, Xuesong Chen, Jing Hu, Hailing Lu, Qingwei Meng, Yan Wang,  and Li Cai
82972-82984
Abstract  |  PDF  |  HTML  |  Order a Reprint

A new humanized in vivo model of KIT D816V+ advanced systemic mastocytosis monitored using a secreted luciferase

A new humanized in vivo model of KIT D816V+ advanced systemic mastocytosis monitored using a secreted luciferase

https://doi.org/10.18632/oncotarget.12824

Siham Bibi, Yanyan Zhang, Caroline Hugonin, Mallorie Depond Mangean, Liang He, Ghaith Wedeh, Jean-Marie Launay, Sjoerd Van Rijn, Thomas Würdinger, Fawzia Louache,  and Michel Arock
82985-83000
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The long noncoding RNA HOXA11 antisense induces tumor progression and stemness maintenance in cervical cancer

The long noncoding RNA HOXA11 antisense induces tumor progression and stemness maintenance in cervical cancer

https://doi.org/10.18632/oncotarget.12863

Hee Jung Kim, Kyung Jin Eoh, Lee Kyung Kim, Eun Ji Nam, Sun Och Yoon, Kun-Hong Kim, Jae Kwan Lee, Sang Wun Kim,  and Young Tae Kim
83001-83016
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PRIMA-1Met suppresses colorectal cancer independent of p53 by targeting MEK

PRIMA-1Met suppresses colorectal cancer independent of p53 by targeting MEK

https://doi.org/10.18632/oncotarget.12940

Tao Lu, Yanmei Zou, Guogang Xu, Jane A. Potter, Garry L. Taylor, Qiuhong Duan, Qin Yang, Huihua Xiong, Hong Qiu, Dawei Ye, Peng Zhang, Shiying Yu, Xianglin Yuan, Feng Zhu, Yihua Wang,  and Hua Xiong
83017-83030
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TLR1 polymorphism rs4833095 as a risk factor for IgA nephropathy in a Chinese Han population: A case-control study

TLR1 polymorphism rs4833095 as a risk factor for IgA nephropathy in a Chinese Han population: A case-control study

https://doi.org/10.18632/oncotarget.12965

Jie Gao, Linting Wei, Jiali Wei, Ganglian Yao, Li Wang, Meng Wang, Xinghan Liu, Cong Dai, Tianbo Jin, Zhijun Dai,  and Rongguo Fu
83031-83039
Abstract  |  PDF  |  HTML  |  Order a Reprint

A fully human anti-CD47 blocking antibody with therapeutic potential for cancer

A fully human anti-CD47 blocking antibody with therapeutic potential for cancer

https://doi.org/10.18632/oncotarget.13349

Dadi Zeng, Qiang Sun, Ang Chen, Jiangfeng Fan, Xiaopeng Yang, Lei Xu, Peng Du, Weiyi Qiu, Weicai Zhang, Shuang Wang,  and Zhiwei Sun
83040-83050
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MDC and BLC are independently associated with the significant risk of early stage lung adenocarcinoma

MDC and BLC are independently associated with the significant risk of early stage lung adenocarcinoma

https://doi.org/10.18632/oncotarget.13031

Yanwei Zhang, Keke Yu, Song Hu, Yuqing Lou, Chunxing Liu, Jianlin Xu, Rong Li, Xueyan Zhang, Huimin Wang,  and Baohui Han
83051-83059
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-31 regulates the cisplatin resistance by targeting Src in gallbladder cancer

MiR-31 regulates the cisplatin resistance by targeting Src in gallbladder cancer

https://doi.org/10.18632/oncotarget.13067

Maolan Li, Wei Chen, Hongchen Zhang, Yong Zhang, Fayong Ke, Xiangsong Wu, Yijian Zhang, Mingzhe Weng, Yingbin Liu,  and Wei Gong
83060-83070
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Marine guanidine alkaloids crambescidins inhibit tumor growth and activate intrinsic apoptotic signaling inducing tumor regression in a colorectal carcinoma zebrafish xenograft model

Marine guanidine alkaloids crambescidins inhibit tumor growth and activate intrinsic apoptotic signaling inducing tumor regression in a colorectal carcinoma zebrafish xenograft model

https://doi.org/10.18632/oncotarget.13068

María Roel, Juan A. Rubiolo, Jorge Guerra-Varela, Siguara B. L. Silva, Olivier P. Thomas, Pablo Cabezas-Sainz, Laura Sánchez, Rafael López,  and Luis M. Botana
83071-83087
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SCIB1, a huIgG1 antibody DNA vaccination, combined with PD-1 blockade induced efficient therapy of poorly immunogenic tumors

SCIB1, a huIgG1 antibody DNA vaccination, combined with PD-1 blockade induced efficient therapy of poorly immunogenic tumors

https://doi.org/10.18632/oncotarget.13070

Wei Xue, Victoria A. Brentville, Peter Symonds, Katherine W. Cook, Hideo Yagita, Rachael L. Metheringham,  and Lindy G. Durrant
83088-83100
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Genetic variants in microRNAs predict non-small cell lung cancer prognosis in Chinese female population in a prospective cohort study

Genetic variants in microRNAs predict non-small cell lung cancer prognosis in Chinese female population in a prospective cohort study

https://doi.org/10.18632/oncotarget.13072

Xia Lingzi, Yin Zhihua, Li Xuelian, Ren Yangwu, Zhang Haibo, Zhao Yuxia,  and Zhou Baosen
83101-83114
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Amplification of MUC1 in prostate cancer metastasis and CRPC development

Amplification of MUC1 in prostate cancer metastasis and CRPC development

https://doi.org/10.18632/oncotarget.13073

Nicholas Wong, Pierre Major, Anil Kapoor, Fengxiang Wei, Judy Yan, Tariq Aziz, Mingxing Zheng, Dulitha Jayasekera, Jean-Claude Cutz, Mathilda Jing Chow,  and Damu Tang
83115-83133
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Smoking increases risks of all-cause and breast cancer specific mortality in breast cancer individuals: a dose-response meta-analysis of prospective cohort studies involving 39725 breast cancer cases

Smoking increases risks of all-cause and breast cancer specific mortality in breast cancer individuals: a dose-response meta-analysis of prospective cohort studies involving 39725 breast cancer cases

https://doi.org/10.18632/oncotarget.13366

Kang Wang, Feng Li, Xiang Zhang, Zhuyue Li,  and Hongyuan Li
83134-83147
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Malignant ascites enhances migratory and invasive properties of ovarian cancer cells with membrane bound IL-6R in vitro

Malignant ascites enhances migratory and invasive properties of ovarian cancer cells with membrane bound IL-6R in vitro

https://doi.org/10.18632/oncotarget.13074

Soochi Kim, HyeRan Gwak, Hee Seung Kim, Boyun Kim, Danny N. Dhanasekaran,  and Yong Sang Song
83148-83159
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Trans-ethnic follow-up of breast cancer GWAS hits using the preferential linkage disequilibrium approach

Trans-ethnic follow-up of breast cancer GWAS hits using the preferential linkage disequilibrium approach

https://doi.org/10.18632/oncotarget.13075

Qianqian Zhu, Lori Shepherd, Kathryn L. Lunetta, Song Yao, Qian Liu, Qiang Hu, Stephen A. Haddad A. Haddad, Lara Sucheston-Campbell, Jeannette T. Bensen, Elisa V. Bandera, Lynn Rosenberg, Song Liu, Christopher A. Haiman, Andrew F. Olshan, Julie R. Palmer,  and Christine B. Ambrosone
83160-83176
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic and clinicopathological significance of long noncoding RNA H19 overexpression in human solid tumors: evidence from a meta-analysis

Prognostic and clinicopathological significance of long noncoding RNA H19 overexpression in human solid tumors: evidence from a meta-analysis

https://doi.org/10.18632/oncotarget.13076

Fang-teng Liu, Hua Pan, Guang-feng Xia, Cheng Qiu,  and Zheng-ming Zhu
83177-83186
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification and validation of differentially expressed proteins in epithelial ovarian cancers using quantitative proteomics

Identification and validation of differentially expressed proteins in epithelial ovarian cancers using quantitative proteomics

https://doi.org/10.18632/oncotarget.13077

Hong Qu, Yuling Chen, Guangming Cao, Chongdong Liu, Jiatong Xu, Haiteng Deng,  and Zhenyu Zhang
83187-83199
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Disadvantage of survival outcomes in widowed patients with colorectal neuroendocrine neoplasm: an analysis of surveillance, epidemiology and end results database

Disadvantage of survival outcomes in widowed patients with colorectal neuroendocrine neoplasm: an analysis of surveillance, epidemiology and end results database

https://doi.org/10.18632/oncotarget.13078

Jing Li, Ying Wang, Fang Han, Zhu Wang, Lichun Xu,  and Jiandong Tong
83200-83207
Abstract  |  PDF  |  HTML  |  Order a Reprint

Acid ceramidase is upregulated in AML and represents a novel therapeutic target

Acid ceramidase is upregulated in AML and represents a novel therapeutic target

https://doi.org/10.18632/oncotarget.13079

Su-Fern Tan, Xin Liu, Todd E. Fox, Brian M. Barth, Arati Sharma, Stephen D. Turner, Andy Awwad, Alden Dewey, Kenichiro Doi, Barbara Spitzer, Mithun Vinod Shah, Samy A.F. Morad, Dhimant Desai, Shantu Amin, Junjia Zhu, Jason Liao, Jong Yun, Mark Kester, David F. Claxton, Hong-Gang Wang, Myles C. Cabot, Edward H. Schuchman, Ross L. Levine, David J. Feith,  and Thomas P. Loughran, Jr
83208-83222
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiRNA-3978 regulates peritoneal gastric cancer metastasis by targeting legumain

MiRNA-3978 regulates peritoneal gastric cancer metastasis by targeting legumain

https://doi.org/10.18632/oncotarget.12917

Yi Zhang, Yuan-yu Wu, Jun-nan Jiang, Xue-song Liu, Fu-jian Ji,  and Xue-dong Fang
83223-83230
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Endothelial cells microparticle-associated protein disulfide isomerase promotes platelet activation in metabolic syndrome

Endothelial cells microparticle-associated protein disulfide isomerase promotes platelet activation in metabolic syndrome

https://doi.org/10.18632/oncotarget.13081

Guan-qi Fan, Ran-ran Qin, Yi-hui Li, Dai-jun Song, Tong-shuai Chen, Wei Zhang, Ming Zhong, Yun Zhang, Yan-qiu Xing,  and Zhi-hao Wang
83231-83240
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathway

PICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathway

https://doi.org/10.18632/oncotarget.13082

Hongbo Chen, Liqiao Han, Hsiangi Tsai, Zhiwei Wang, Yanping Wu, Yanhong Duo, Wei Cao, Lijun Chen, Zhirong Tan, Ning Xu, Xianzhang Huang, Junhua Zhuang,  and Laiqiang Huang
83241-83257
Abstract  |  PDF  |  HTML  |  Order a Reprint

Sequential delivery of therapeutic agents using a rationally designed disulfide-linked glycolipid-like nanocarrier

Sequential delivery of therapeutic agents using a rationally designed disulfide-linked glycolipid-like nanocarrier

https://doi.org/10.18632/oncotarget.13083

Yingwen Hu, Na Liu, Bolin Cheng, Yanan Tan, Lijuan Wen, Hong Yuan,  and Fuqiang Hu
83258-83269
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeted ultra-deep sequencing unveils a lack of driver-gene mutations linking non-hereditary gastrointestinal stromal tumors and highly prevalent second primary malignancies: random or nonrandom, that is the question

Targeted ultra-deep sequencing unveils a lack of driver-gene mutations linking non-hereditary gastrointestinal stromal tumors and highly prevalent second primary malignancies: random or nonrandom, that is the question

https://doi.org/10.18632/oncotarget.12452

Bo-Ru Lai, Yu-Tung Wu, Yung-Chia Kuo, Hung-Chih Hsu, Jen-Shi Chen, Tse-Ching Chen, Ren-Chin Wu, Cheng-Tang Chiu, Chun-Nan Yeh,  and Ta-Sen Yeh
83270-83277
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ERN1 and ALPK1 inhibit differentiation of bi-potential tumor-initiating cells in human breast cancer

ERN1 and ALPK1 inhibit differentiation of bi-potential tumor-initiating cells in human breast cancer

https://doi.org/10.18632/oncotarget.13086

Juliane Strietz, Stella S. Stepputtis, Bogdan-Tiberius Preca, Corinne Vannier, Mihee M. Kim, David J. Castro, Qingyan Au, Melanie Boerries, Hauke Busch, Pedro Aza-Blanc, Susanne Heynen-Genel, Peter Bronsert, Bernhard Kuster, Bernhard Kuster, Elmar Stickeler, Thomas Brabletz, Robert G. Oshima,  and Jochen Maurer
83278-83293
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mutations or copy number losses of CD58 and TP53 genes in diffuse large B cell lymphoma are independent unfavorable prognostic factors

Mutations or copy number losses of CD58 and TP53 genes in diffuse large B cell lymphoma are independent unfavorable prognostic factors

https://doi.org/10.18632/oncotarget.13065

Yang Cao, Tao Zhu, Peiling Zhang, Min Xiao, Shuhua Yi, Yan Yang, Qinlu Li, Shaopin g Ling, Yafei Wang, Lili Gao, Li Zhu, Jue Wang, Na Wang, Liang Huang, Peihong Zhang, Qiongli Zhai, Lugui Qiu,  and Jianfeng Zhou
83294-83307
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Suppression of the metastatic spread of breast cancer by DN10764 (AZD7762)-mediated inhibition of AXL signaling

Suppression of the metastatic spread of breast cancer by DN10764 (AZD7762)-mediated inhibition of AXL signaling

https://doi.org/10.18632/oncotarget.13088

Joon-Suk Park, ChuHee Lee, Hyun-Kyoung Kim, Dayea Kim, Jung Beom Son, Eunhwa Ko, Joong-Heui Cho, Nam-Doo Kim, Hong-Yan Nan, Choong-Yong Kim, Sukkyoon Yoon, Sun-Hwa Lee,  and Hwan Geun Choi
83308-83318
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Protocol for qRT-PCR analysis from formalin fixed paraffin embedded tissue sections from diffuse large b-cell lymphoma: Validation of the six-gene predictor score

Protocol for qRT-PCR analysis from formalin fixed paraffin embedded tissue sections from diffuse large b-cell lymphoma: Validation of the six-gene predictor score

https://doi.org/10.18632/oncotarget.13066

Nilgun Tekin, Nader Omidvar, Tim Peter Morris, Paulette Conget, Flavia Bruna, Botond Timar, Eva Gagyi, Ranjan Basak, Omkar Naik, Chirayu Auewarakul, Narongrit Sritana, Debora Levy, Juliano Cerci, Sergio Paulo Bydlowski, Juliana Pereira, Mark Pierre Dimamay, Filipinas Natividad, June-Key hung, Nevin Belder, Isinsu Kuzu, Diana Paez, Maurizio Dondi, Robert Carr, Hilal Ozdag,  and Rose Ann Padua
83319-83329
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Altered expression of miRNAs and methylation of their promoters are correlated in neuroblastoma

Altered expression of miRNAs and methylation of their promoters are correlated in neuroblastoma

https://doi.org/10.18632/oncotarget.13090

Marco Maugeri, Davide Barbagallo, Cristina Barbagallo, Barbara Banelli, Stefania Di Mauro, Francesco Purrello, Gaetano Magro, Marco Ragusa, Cinzia Di Pietro, Massimo Romani,  and Michele Purrello
83330-83341
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Novel metastatic models of esophageal adenocarcinoma derived from FLO-1 cells highlight the importance of E-cadherin in cancer metastasis

Novel metastatic models of esophageal adenocarcinoma derived from FLO-1 cells highlight the importance of E-cadherin in cancer metastasis

https://doi.org/10.18632/oncotarget.13391

David S. Liu, Sanne J.M. Hoefnagel, Oliver M. Fisher, Kausilia K. Krishnadath, Karen G. Montgomery, Rita A. Busuttil, Andrew J. Colebatch, Matthew Read, Cuong P. Duong, Wayne A. Phillips,  and Nicholas J. Clemons
83342-83358
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gene expression profile induced by arsenic trioxide in chronic lymphocytic leukemia cells reveals a central role for heme oxygenase-1 in apoptosis and regulation of matrix metalloproteinase-9

Gene expression profile induced by arsenic trioxide in chronic lymphocytic leukemia cells reveals a central role for heme oxygenase-1 in apoptosis and regulation of matrix metalloproteinase-9

https://doi.org/10.18632/oncotarget.13091

Irene Amigo-Jiménez, Elvira Bailón, Noemí Aguilera-Montilla, José A. García- Marco,  and Angeles García-Pardo
83359-83377
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activation of the basal cell carcinoma pathway in a patient with CNS HGNET-BCOR diagnosis: consequences for personalized targeted therapy

Activation of the basal cell carcinoma pathway in a patient with CNS HGNET-BCOR diagnosis: consequences for personalized targeted therapy

https://doi.org/10.18632/oncotarget.13092

Claudia Paret, Johanna Theruvath, Alexandra Russo, Bettina Kron, Khalifa El Malki, Nadine Lehmann, Arthur Wingerter, Marie A. Neu, Aslihan Gerhold-Ay, Wolfgang Wagner, Clemens Sommer, Torsten Pietsch, Larissa Seidmann,  and Jörg Faber
83378-83391
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CD19-specific triplebody SPM-1 engages NK and γδ T cells for rapid and efficient lysis of malignant B-lymphoid cells

CD19-specific triplebody SPM-1 engages NK and γδ T cells for rapid and efficient lysis of malignant B-lymphoid cells

https://doi.org/10.18632/oncotarget.13110

Christian B. Schiller, Todd A. Braciak, Nadja C. Fenn, Ursula J. E. Seidel, Claudia C. Roskopf, Sarah Wildenhain, Annemarie Honegger, Ingo A. Schubert, Alexandra Schele, Kerstin Lämmermann, Georg H. Fey, Uwe Jacob, Peter Lang, Karl-Peter Hopfner,  and Fuat S. Oduncu
83392-83408
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pubertal and adult windows of susceptibility to a high animal fat diet in Trp53-null mammary tumorigenesis

Pubertal and adult windows of susceptibility to a high animal fat diet in Trp53-null mammary tumorigenesis

https://doi.org/10.18632/oncotarget.13112

Yirong Zhu, Mark D. Aupperlee, Yong Zhao, Ying Siow Tan, Erin L. Kirk, Xuezheng Sun, Melissa A. Troester, Richard C. Schwartz,  and Sandra Z. Haslam
83409-83423
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FGFR signaling maintains a drug persistent cell population following epithelial-mesenchymal transition

FGFR signaling maintains a drug persistent cell population following epithelial-mesenchymal transition

https://doi.org/10.18632/oncotarget.13117

Wells S. Brown, Saeed Salehin Akhand,  and Michael K. Wendt
83424-83436
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Heme oxygenase-1 gene promoter polymorphisms are associated with coronary heart disease and restenosis after percutaneous coronary intervention: a meta-analysis

Heme oxygenase-1 gene promoter polymorphisms are associated with coronary heart disease and restenosis after percutaneous coronary intervention: a meta-analysis

https://doi.org/10.18632/oncotarget.13118

Ming-Ming Zhang, Ying-Ying Zheng, Ying Gao, Jing-Zhan Zhang, Fen Liu, Yi-Ning Yang, Xiao-Mei Li, Yi-Tong Ma,  and Xiang Xie
83437-83450
Abstract  |  PDF  |  HTML  |  Order a Reprint

Synthetic paclitaxel-octreotide conjugate reversing the resistance of A2780/Taxol to paclitaxel in xenografted tumor in nude mice

Synthetic paclitaxel-octreotide conjugate reversing the resistance of A2780/Taxol to paclitaxel in xenografted tumor in nude mice

https://doi.org/10.18632/oncotarget.13120

Xi Chen, Xiao-Yu Zhang, Yang Shen, Li-Li Fan, Mu-Lan Ren,  and Yong-Ping Wu
83451-83461
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tristetraprolin disables prostate cancer maintenance by impairing proliferation and metabolic function

Tristetraprolin disables prostate cancer maintenance by impairing proliferation and metabolic function

https://doi.org/10.18632/oncotarget.13128

Anders E. Berglund, Kristen E.N. Scott, Weimin Li, Chunying Yang, Mario R. Fernandez, Franz X. Schaub, John L. Cleveland,  and Robert J. Rounbehler
83462-83475
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Autophagy as an emerging therapy target for ovarian carcinoma

Autophagy as an emerging therapy target for ovarian carcinoma

https://doi.org/10.18632/oncotarget.13080

Lei Zhan, Yu Zhang, Wenyan Wang, Enxue Song, Yijun Fan, Jun Li,  and Bing Wei
83476-83487
Abstract  |  PDF  |  HTML  |  Order a Reprint

SUMOylated MAFB promotes colorectal cancer tumorigenesis

SUMOylated MAFB promotes colorectal cancer tumorigenesis

https://doi.org/10.18632/oncotarget.13129

Lin-Sen Yang, Xiao-Jian Zhang, Yin-Yin Xie, Xiao-Jian Sun, Ren Zhao,  and Qiu-Hua Huang
83488-83501
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting ABCB1 (MDR1) in multi-drug resistant osteosarcoma cells using the CRISPR-Cas9 system to reverse drug resistance

Targeting ABCB1 (MDR1) in multi-drug resistant osteosarcoma cells using the CRISPR-Cas9 system to reverse drug resistance

https://doi.org/10.18632/oncotarget.13148

Tang Liu, Zhihong Li, Qing Zhang, Karen De Amorim Bernstein, Santiago Lozano-Calderon, Edwin Choy, Francis J. Hornicek,  and Zhenfeng Duan
83502-83513
Abstract  |  PDF  |  HTML  |  Order a Reprint

Senescent stromal cell-induced divergence and therapeutic resistance in T cell acute lymphoblastic leukemia/lymphoma

Senescent stromal cell-induced divergence and therapeutic resistance in T cell acute lymphoblastic leukemia/lymphoma

https://doi.org/10.18632/oncotarget.13158

David M. Habiel, Nicolas Krepostman, Michael Lilly, Karen Cavassani, Ana Lucia Coelho, Takehiko Shibata, Kojo Elenitoba-Johnson,  and Cory M. Hogaboam
83514-83529
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel benzofuran derivative, ACDB, induces apoptosis of human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress

A novel benzofuran derivative, ACDB, induces apoptosis of human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress

https://doi.org/10.18632/oncotarget.13171

Chen-Ming Su, Chien-Yu Chen, Tingting Lu, Yi Sun, Weimin Li, Yuan-Li Huang, Chun-Hao Tsai, Chih-Shiang Chang,  and Chih-Hsin Tang
83530-83543
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value of total lesion glycolysis of baseline 18F-fluorodeoxyglucose positron emission tomography/computed tomography in diffuse large B-cell lymphoma

Prognostic value of total lesion glycolysis of baseline 18F-fluorodeoxyglucose positron emission tomography/computed tomography in diffuse large B-cell lymphoma

https://doi.org/10.18632/oncotarget.13180

Mingge Zhou, Yumei Chen, Honghui Huang, Xiang Zhou, Jianjun Liu,  and Gang Huang
83544-83553
Abstract  |  PDF  |  HTML  |  Order a Reprint

Senescent fibroblast-derived Chemerin promotes squamous cell carcinoma migration

Senescent fibroblast-derived Chemerin promotes squamous cell carcinoma migration

https://doi.org/10.18632/oncotarget.13446

Vida Farsam, Abhijit Basu, Martina Gatzka, Nicolai Treiber, Lars A. Schneider, Medhanie A. Mulaw, Tanja Lucas, Stefan Kochanek, Reinhard Dummer, Mitchell P. Levesque, Meinhard Wlaschek,  and Karin Scharffetter-Kochanek
83554-83569
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

O-glycan sialylation alters galectin-3 subcellular localization and decreases chemotherapy sensitivity in gastric cancer

O-glycan sialylation alters galectin-3 subcellular localization and decreases chemotherapy sensitivity in gastric cancer

https://doi.org/10.18632/oncotarget.13192

Sofia N. Santos, Mara S. Junqueira, Guilherme Francisco, Manuel Vilanova, Ana Magalhães, Marcelo Dias Baruffi, Roger Chammas, Adrian L. Harris, Celso A. Reis,  and Emerson S. Bernardes
83570-83587
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Apocynin attenuates angiotensin II-induced vascular smooth muscle cells osteogenic switching via suppressing extracellular signal-regulated kinase 1/2

Apocynin attenuates angiotensin II-induced vascular smooth muscle cells osteogenic switching via suppressing extracellular signal-regulated kinase 1/2

https://doi.org/10.18632/oncotarget.13193

Weijing Feng, Kun Zhang, Yu Liu, Jie Chen, Qingqing Cai, Yinyin Zhang, Mongheng Wang, Jingfeng Wang,  and Hui Huang
83588-83600
Abstract  |  PDF  |  HTML  |  Order a Reprint

Pancreatic carcinoma-specific immunotherapy using novel tumor specific cytotoxic T cells

Pancreatic carcinoma-specific immunotherapy using novel tumor specific cytotoxic T cells

https://doi.org/10.18632/oncotarget.13469

Jianjun Lei, Zheng Wu, Zhengdong Jiang, Jiahui Li, Liang Zong, Xin Chen, Wanxing Duan, Qinhong Xu, Lun Zhang, Liang Han, Qingyong Ma, Zheng Wang,  and Dong Zhang
83601-83610
Abstract  |  PDF  |  HTML  |  Order a Reprint

Galectin-1 induces invasion and the epithelial-mesenchymal transition in human gastric cancer cells via non-canonical activation of the hedgehog signaling pathway

Galectin-1 induces invasion and the epithelial-mesenchymal transition in human gastric cancer cells via non-canonical activation of the hedgehog signaling pathway

https://doi.org/10.18632/oncotarget.13201

Yang Chong, Dong Tang, Jun Gao, Xuetong Jiang, Chuanqi Xu, Qingquan Xiong, Yuqin Huang, Jie Wang, Huaicheng Zhou, Youquan Shi,  and Daorong Wang
83611-83626
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Transcription factor LSF-DNMT1 complex dissociation by FQI1 leads to aberrant DNA methylation and gene expression

Transcription factor LSF-DNMT1 complex dissociation by FQI1 leads to aberrant DNA methylation and gene expression

https://doi.org/10.18632/oncotarget.13271

Hang Gyeong Chin, V.k. Chaithanya Ponnaluri, Guoqiang Zhang, Pierre-Olivier Estève, Scott E. Schaus, Ulla Hansen,  and Sriharsa Pradhan
83627-83640
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Bisdemethoxycurcumin exerts pro-apoptotic effects in human pancreatic adenocarcinoma cells through mitochondrial dysfunction and a GRP78-dependent pathway

Bisdemethoxycurcumin exerts pro-apoptotic effects in human pancreatic adenocarcinoma cells through mitochondrial dysfunction and a GRP78-dependent pathway

https://doi.org/10.18632/oncotarget.13272

Haopeng Yang, Shengjun Fan, Yu An, Xin Wang, Yan Pan, Yilixiati Xiaokaiti, Jianhui Duan, Xin Li, Lu Tie, Min Ye,  and Xuejun Li
83641-83656
Abstract  |  PDF  |  HTML  |  Order a Reprint

Refractory pituitary adenoma: a novel classification for pituitary tumors

Refractory pituitary adenoma: a novel classification for pituitary tumors

https://doi.org/10.18632/oncotarget.13274

Congxin Dai, Ming Feng, Xiaohai Liu, Sihai Ma, Bowen Sun, Xinjie Bao, Yong Yao, Kan Deng, Yu Wang, Bing Xing, Wei Lian, Dingrong Zhong, Wenbin Ma,  and Renzhi Wang
83657-83668
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Myoferlin is a novel exosomal protein and functional regulator of cancer-derived exosomes

Myoferlin is a novel exosomal protein and functional regulator of cancer-derived exosomes

https://doi.org/10.18632/oncotarget.13276

Arnaud Blomme, Karim Fahmy, Olivier Peulen, Brunella Costanza, Marie Fontaine, Ingrid Struman, Dominique Baiwir, Edwin de Pauw, Marc Thiry, Akeila Bellahcène, Vincent Castronovo,  and Andrei Turtoi
83669-83683
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Platelet derived growth factor receptor alpha mediates nodal metastases in papillary thyroid cancer by driving the epithelial-mesenchymal transition

Platelet derived growth factor receptor alpha mediates nodal metastases in papillary thyroid cancer by driving the epithelial-mesenchymal transition

https://doi.org/10.18632/oncotarget.13299

Esther Ekpe-Adewuyi, Ana Lopez-Campistrous, Xiaoyun Tang, David N. Brindley,  and Todd P. W. McMullen
83684-83700
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CXCR4 increases in-vivo glioma perivascular invasion, and reduces radiation induced apoptosis: A genetic knockdown study

CXCR4 increases in-vivo glioma perivascular invasion, and reduces radiation induced apoptosis: A genetic knockdown study

https://doi.org/10.18632/oncotarget.13295

Viveka Nand Yadav, Daniel Zamler, Gregory J. Baker, Padma Kadiyala, Anat Erdreich-Epstein, Ana C. DeCarvalho, Tom Mikkelsen, Maria G. Castro,  and Pedro R. Lowenstein
83701-83719
Abstract  |  PDF  |  HTML  |  Order a Reprint

Sesamin inhibits IL-1β-stimulated inflammatory response in human osteoarthritis chondrocytes by activating Nrf2 signaling pathway

Sesamin inhibits IL-1β-stimulated inflammatory response in human osteoarthritis chondrocytes by activating Nrf2 signaling pathway

https://doi.org/10.18632/oncotarget.13360

Pengyu Kong, Guanghua Chen, Anlong Jiang, Yufu Wang, Chengchao Song, Jinpeng Zhuang, Chunyang Xi, Guangxi Wang, Ye Ji,  and Jinglong Yan
83720-83726
Abstract  |  PDF  |  HTML  |  Order a Reprint

LncRNA GAS5 contributes to lymphatic metastasis in colorectal cancer

LncRNA GAS5 contributes to lymphatic metastasis in colorectal cancer

https://doi.org/10.18632/oncotarget.13384

Yongbin Zheng, Dan Song, Kuang Xiao, Cao Yang, Yu Ding, Wenhong Deng,  and Shilun Tong
83727-83734
Abstract  |  PDF  |  HTML  |  Order a Reprint

Immunohistochemical staining of ERG and SOX9 as potential biomarkers of docetaxel response in patients with metastatic castration-resistant prostate cancer

Immunohistochemical staining of ERG and SOX9 as potential biomarkers of docetaxel response in patients with metastatic castration-resistant prostate cancer

https://doi.org/10.18632/oncotarget.13407

Wan Song, Ghee Young Kwon, Jeong Hoon Kim, Joung Eun Lim, Hwang Gyun Jeon, Seong Il Seo, Seong Soo Jeon, Han Yong Choi, Byong Chang Jeong,  and Hyun Moo Lee
83735-83743
Abstract  |  PDF  |  HTML  |  Order a Reprint

Effects of Abies sibirica terpenes on cancer- and aging-associated pathways in human cells

Effects of Abies sibirica terpenes on cancer- and aging-associated pathways in human cells

https://doi.org/10.18632/oncotarget.13467

Anna Kudryavtseva, George Krasnov, Anastasiya Lipatova, Boris Alekseev, Faniya Maganova, Mikhail Shaposhnikov, Maria Fedorova, Anastasiya Snezhkina,  and Alexey Moskalev
83744-83754
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Icaritin inhibits the expression of alpha-fetoprotein in hepatitis B virus-infected hepatoma cell lines through post-transcriptional regulation

Icaritin inhibits the expression of alpha-fetoprotein in hepatitis B virus-infected hepatoma cell lines through post-transcriptional regulation

https://doi.org/10.18632/oncotarget.13194

Chao Zhang, Hui Li, Wei Jiang, Xiaowei Zhang,  and Gang Li
83755-83766
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Impact of age on the survival of pediatric leukemia: an analysis of 15083 children in the SEER database

Impact of age on the survival of pediatric leukemia: an analysis of 15083 children in the SEER database

https://doi.org/10.18632/oncotarget.11765

Yaping Wang, Jie Huang, Liucheng Rong, Peng Wu, Meiyun Kang, Xuejie Zhang, Qin Lu,  and Yongjun Fang
83767-83774
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Diagnostic accuracy of high-risk HPV genotyping in women with high-grade cervical lesions: evidence for improving the cervical cancer screening strategy in China

Diagnostic accuracy of high-risk HPV genotyping in women with high-grade cervical lesions: evidence for improving the cervical cancer screening strategy in China

https://doi.org/10.18632/oncotarget.11959

Huihui Xu, Aifen Lin, Xiujuan Shao, Weiwu Shi, Yang Zhang,  and Weihua Yan
83775-83783
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nationwide population-based study reveals increased malignancy risk in taiwanese liver transplant recipients

Nationwide population-based study reveals increased malignancy risk in taiwanese liver transplant recipients

https://doi.org/10.18632/oncotarget.11965

Yung Fong Tsai, Hsiu Pin Chen, Fu Chao Liu, Shih Hao Liu, Chun Yu Chen, Chih Wen Cheng,  and Jr Rung Lin
83784-83794
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical characteristics and prognoses of six patients with multicentric giant cell tumor of the bone

Clinical characteristics and prognoses of six patients with multicentric giant cell tumor of the bone

https://doi.org/10.18632/oncotarget.13057

Chenglei Liu, Yawen Tang, Mei Li, Qiong Jiao, Huizhen Zhang, Qingcheng Yang,  and Weiwu Yao
83795-83805
Abstract  |  PDF  |  HTML  |  Order a Reprint

Retrospective analysis of transarterial chemoembolization and sorafenib in Chinese patients with unresectable and recurrent hepatocellular carcinoma

Retrospective analysis of transarterial chemoembolization and sorafenib in Chinese patients with unresectable and recurrent hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.11514

Xuying Wan, Xiaofeng Zhai, Zhenlin Yan, Pinghua Yang, Jun Li, Dong Wu, Kui Wang, Yong Xia,  and Feng Shen
83806-83816
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Case Reports

Placental immune editing switch (PIES): learning about immunomodulatory pathways from a unique case report

Placental immune editing switch (PIES): learning about immunomodulatory pathways from a unique case report

https://doi.org/10.18632/oncotarget.13306

Miguel H. Bronchud, Francesc Tresserra, Wenjie Xu, Sarah Warren, Maite Cusido, Bernat Zantop, Ana Claudia Zenclussen,  and Alessandra Cesano
83817-83827
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Corrections

Correction: Infiltrating mast cells enhance prostate cancer invasion via altering LncRNA-HOTAIR/PRC2-androgen receptor (AR)-MMP9 signals and increased stem/progenitor cell population

Correction: Infiltrating mast cells enhance prostate cancer invasion via altering LncRNA-HOTAIR/PRC2-androgen receptor (AR)-MMP9 signals and increased stem/progenitor cell population

https://doi.org/10.18632/oncotarget.13912

Lei Li, Qiang Dang, Hongjun Xie, Zhao Yang, Dalin He, Liang Liang, Wenbing Song, Shuyuan Yeh,  and Chawnshang Chang
83828-83828
Correction  |  PDF

Correction: Infiltrated pre-adipocytes increase prostate cancer metastasis via modulation of the miR-301a/androgen receptor (AR)/TGF-β1/Smad/MMP9 signals

Correction: Infiltrated pre-adipocytes increase prostate cancer metastasis via modulation of the miR-301a/androgen receptor (AR)/TGF-β1/Smad/MMP9 signals

https://doi.org/10.18632/oncotarget.13913

Hongjun Xie, Lei Li, Guodong Zhu, Qiang Dang, Zhenkun Ma, Dalin He, Luke Chang, Wenbing Song, Hong-Chiang Chang, John J. Krolewski, Kent L. Nastiuk, Shuyuan Yeh,  and Chawnshang Chang
83829-83830
Correction  |  PDF


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