Oncotarget

Vol 7, No 49

December 6, 2016

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About The Cover

About the cover: The cover for issue 49 of Oncotarget features Figure 1, 'Regional plots of breast cancer risk association at 4q21,' from Hamdi, et al.

Table of Contents

Editorial

Acidic domains: “converse readers” for acetylation code

Acidic domains: “converse readers” for acetylation code

https://doi.org/10.18632/oncotarget.12989

Donglai Wang, Ning Kon,  and Wei Gu
80101-80102
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CRISPR-mediated multiplexed genetic manipulation

CRISPR-mediated multiplexed genetic manipulation

https://doi.org/10.18632/oncotarget.13371

Lin Lin, Johan Vad-Nielsen,  and Yonglun Luo
80103-80104
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Axl in ovarian cancer: a step forward for clinical breakthrough?

Axl in ovarian cancer: a step forward for clinical breakthrough?

https://doi.org/10.18632/oncotarget.13457

Marialuisa Sensi, Silvana Canevari,  and Antonella Tomassetti
80105-80106
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Redox and metabolic regulation of transcription

Redox and metabolic regulation of transcription

https://doi.org/10.18632/oncotarget.13459

Glenn Marsboom,  and Jalees Rehman
80107-80108
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Double hit mouse model of Parkinson’s disease

Double hit mouse model of Parkinson’s disease

https://doi.org/10.18632/oncotarget.13460

Tommaso Schirinzi, Giuseppina Martella,  and Antonio Pisani
80109-80110
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Editorial: Neuroscience

Pharmacological agonists for more-targeted CNS radio-pharmaceuticals

Pharmacological agonists for more-targeted CNS radio-pharmaceuticals

https://doi.org/10.18632/oncotarget.13418

Luc Zimmer
80111-80112
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Priority Research Papers

MEK1 is required for the development of NRAS-driven leukemia

MEK1 is required for the development of NRAS-driven leukemia

https://doi.org/10.18632/oncotarget.12555

Joanna D. Nowacka, Christian Baumgartner, Cristiana Pelorosso, Mareike Roth, Johannes Zuber,  and Manuela Baccarini
80113-80130
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Rapamycin enhances survival in a Drosophila model of mitochondrial disease

Rapamycin enhances survival in a Drosophila model of mitochondrial disease

https://doi.org/10.18632/oncotarget.12560

Adrienne Wang, Jacob Mouser, Jason Pitt, Daniel Promislow,  and Matt Kaeberlein
80131-80139
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Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21

Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21

https://doi.org/10.18632/oncotarget.12818

Yosr Hamdi, Penny Soucy, Véronique Adoue, Kyriaki Michailidou, Sander Canisius, Audrey Lemaçon, Arnaud Droit, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Caroline Baynes, Carl Blomqvist, Natalia V. Bogdanova, Stig E. Bojesen, Manjeet K. Bolla, Bernardo Bonanni, Anne-Lise Borresen-Dale, Judith S. Brand, Hiltrud Brauch, Hermann Brenner, Annegien Broeks, Barbara Burwinkel, Jenny Chang-Claude, NBCS Collaborators, Fergus J. Couch, Angela Cox, Simon S. Cross, Kamila Czene, Hatef Darabi, Joe Dennis, Peter Devilee, Thilo Dörk, Isabel Dos-Santos-Silva, Mikael Eriksson, Peter A. Fasching, Jonine Figueroa, Henrik Flyger, Montserrat García-Closas, Graham G. Giles, Mark S. Goldberg, Anna González-Neira, Grethe Grenaker-Alnæs, Pascal Guénel, Lothar Haeberle, Christopher A. Haiman, Ute Hamann, Emily Hallberg, Maartje J. Hooning, John L. Hopper, Anna Jakubowska, Michael Jones, Maria Kabisch, Vesa Kataja, Diether Lambrechts, Loic Le Marchand, Annika Lindblom, Jan Lubinski, Arto Mannermaa, Mel Maranian, Sara Margolin, Frederik Marme, Roger L. Milne, Susan L. Neuhausen, Heli Nevanlinna, Patrick Neven, Curtis Olswold, Julian Peto, Dijana Plaseska-Karanfilska, Katri Pylkäs, Paolo Radice, Anja Rudolph, Elinor J. Sawyer, Marjanka K. Schmidt, Xiao-Ou Shu, Melissa C. Southey, Anthony Swerdlow, Rob A.E.M. Tollenaar, Ian Tomlinson, Diana Torres, , Celine Vachon, Ans M.W. Van Den Ouweland, Qin Wang, Robert Winqvist, kConFab/AOCS Investigators, Wei Zheng, Javier Benitez, Georgia Chenevix-Trench, Alison Easton, Tomi Pastinen, Silje Nord,  and Jacques Simard
80140-80163
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Specific micro-RNA expression patterns distinguish the basal and luminal subtypes of muscle-invasive bladder cancer

Specific micro-RNA expression patterns distinguish the basal and luminal subtypes of muscle-invasive bladder cancer

https://doi.org/10.18632/oncotarget.13284

Andrea E. Ochoa, Woonyoung Choi, Xiaoping Su, Arlene Siefker-Radtke, Bogdan Czerniak, Colin Dinney,  and David J. McConkey
80164-80174
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MDA-9/Syntenin (SDCBP) modulates small GTPases RhoA and Cdc42 via transforming growth factor β1 to enhance epithelial-mesenchymal transition in breast cancer

MDA-9/Syntenin (SDCBP) modulates small GTPases RhoA and Cdc42 via transforming growth factor β1 to enhance epithelial-mesenchymal transition in breast cancer

https://doi.org/10.18632/oncotarget.13373

Mitchell E. Menezes, Xue-Ning Shen, Swadesh K. Das, Luni Emdad, Devanand Sarkar,  and Paul B. Fisher
80175-80189
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Targeting GLI by GANT61 involves mechanisms dependent on inhibition of both transcription and DNA licensing

Targeting GLI by GANT61 involves mechanisms dependent on inhibition of both transcription and DNA licensing

https://doi.org/10.18632/oncotarget.13376

Ruowen Zhang, Jiahui Wu, Sylvain Ferrandon, Katie J. Glowacki,  and Janet A. Houghton
80190-80207
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Research Papers: Gerotarget (Focus on Aging)

Mitochondria-targeted antioxidant SkQ1 reduces age-related alterations in the ultrastructure of the lacrimal gland

Mitochondria-targeted antioxidant SkQ1 reduces age-related alterations in the ultrastructure of the lacrimal gland

https://doi.org/10.18632/oncotarget.13303

Lora E. Bakeeva, Chupalav M. Eldarov, Irina M. Vangely, Nataliya G. Kolosova,  and Valeriya B. Vays
80208-80222
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Research Papers: Pathology

Glycine protects against high sucrose and high fat-induced non-alcoholic steatohepatitis in rats

Glycine protects against high sucrose and high fat-induced non-alcoholic steatohepatitis in rats

https://doi.org/10.18632/oncotarget.12831

Xin Zhou, Dewu Han, Ruiling Xu, Huiwen Wu, Chongxiao Qu, Feng Wang, Xiangyu Wang,  and Yuanchang Zhao
80223-80237
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Human airway smooth muscle cell proliferation from asthmatics is negatively regulated by semaphorin3A

Human airway smooth muscle cell proliferation from asthmatics is negatively regulated by semaphorin3A

https://doi.org/10.18632/oncotarget.12884

Hesam Movassagh, Nazanin Tatari, Lianyu Shan, Latifa Koussih, Duaa Alsubait, Mahdi Khattabi, Naresh S. Redhu, Michael Roth, Michael Tamm, Jamila Chakir,  and Abdelilah S. Gounni
80238-80251
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Circulation autoantibody against Lamin A/C in patients with Sjögren’s syndrome

Circulation autoantibody against Lamin A/C in patients with Sjögren’s syndrome

https://doi.org/10.18632/oncotarget.13256

Wen Zhang, Chunyan Zhang, Peng Chen, Chunhe Yang, Xianfeng Gan, Muhammad Hussain, Yiping Xun, Yaping Tian,  and Hongwu Du
80252-80261
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Research Papers: Immunology

Andrographolide ameliorates OVA-induced lung injury in mice by suppressing ROS-mediated NF-κB signaling and NLRP3 inflammasome activation

Andrographolide ameliorates OVA-induced lung injury in mice by suppressing ROS-mediated NF-κB signaling and NLRP3 inflammasome activation

https://doi.org/10.18632/oncotarget.12918

Shuang Peng, Jian Gao, Wen Liu, Chunhong Jiang, Xiaoling Yang, Yang Sun, Wenjie Guo,  and Qiang Xu
80262-80274
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Avian leukosis virus subgroup J induces VEGF expression via NF-κB/PI3K-dependent IL-6 production

Avian leukosis virus subgroup J induces VEGF expression via NF-κB/PI3K-dependent IL-6 production

https://doi.org/10.18632/oncotarget.13282

Yanni Gao, Yao Zhang, Yongxiu Yao, Xiaolu Guan, Yongzhen Liu, Xiaole Qi, Yongqiang Wang, Changjun Liu, Yanping Zhang, Honglei Gao, Venugopal Nair, Xiaomei Wang,  and Yulong Gao
80275-80287
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P2rx4 deficiency in mice alleviates allergen-induced airway inflammation

P2rx4 deficiency in mice alleviates allergen-induced airway inflammation

https://doi.org/10.18632/oncotarget.13375

Andreas Zech, Benjamin Wiesler, Cemil Korcan Ayata, Tilmann Schlaich, Thorsten Dürk, Madelon Hoßfeld, Nicolas Ehrat, Sanja Cicko,  and Marco Idzko
80288-80297
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Smad4 in T cells plays a protective role in the development of autoimmune Sjögren’s syndrome in the nonobese diabetic mouse

Smad4 in T cells plays a protective role in the development of autoimmune Sjögren’s syndrome in the nonobese diabetic mouse

https://doi.org/10.18632/oncotarget.13437

Donghee Kim, Jae Young Kim,  and Hee-Sook Jun
80298-80312
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Dietary grape seed proanthocyanidins (GSPs) improve weaned intestinal microbiota and mucosal barrier using a piglet model

Dietary grape seed proanthocyanidins (GSPs) improve weaned intestinal microbiota and mucosal barrier using a piglet model

https://doi.org/10.18632/oncotarget.13450

Meng Han, Peixia Song, Chang Huang, Arash Rezaei, Shabnam Farrar, Michael A. Brown,  and Xi Ma
80313-80326
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Research Papers: Chromosome

Clinical and genomic evaluation of a Chinese patient with a novel deletion associated with Phelan–McDermid syndrome

Clinical and genomic evaluation of a Chinese patient with a novel deletion associated with Phelan–McDermid syndrome

https://doi.org/10.18632/oncotarget.12552

Dongzhu Lei, Shaoyuan Li, Santasree Banerjee, Haoqing Zhang, Caiyun Li, Shuai Hou, Danjing Chen, Haiying Yan, Hanmei Li, Huan Huan peng, Saijun Liu, Xinxin Zhang, Zhiyu Peng, Jian Wang, Huanming Yang, Hui Huang,  and Jing Wu
80327-80335
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers

SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status

SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status

https://doi.org/10.18632/oncotarget.12015

Ha Yong Song, Marco Biancucci, Hong-Jun Kang, Carol O’Callaghan, Seong-Hoon Park, Daniel R. Principe, Haiyan Jiang, Yufan Yan, Karla Fullner Satchell, Kirtee Raparia, David Gius,  and Athanassios Vassilopoulos
80336-80349
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ribosomal protein S3 (rpS3) secreted from various cancer cells is N-linked glycosylated

Ribosomal protein S3 (rpS3) secreted from various cancer cells is N-linked glycosylated

https://doi.org/10.18632/oncotarget.10180

YongJoong Kim, Min Seon Lee, Hag Dong Kim,  and Joon Kim
80350-80362
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-151-5p, targeting chromatin remodeler SMARCA5, as a marker for the BRCAness phenotype

miR-151-5p, targeting chromatin remodeler SMARCA5, as a marker for the BRCAness phenotype

https://doi.org/10.18632/oncotarget.10345

Stefania Tommasi, Rosamaria Pinto, Katia Danza, Brunella Pilato, Orazio Palumbo, Lucia Micale,  and Simona De Summa
80363-80372
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Strategies for power calculations in predictive biomarker studies in survival data

Strategies for power calculations in predictive biomarker studies in survival data

https://doi.org/10.18632/oncotarget.12124

Dung-Tsa Chen, Po-Yu Huang, Hui-Yi Lin, Eric B. Haura, Scott J. Antonia, W. Douglas Cress,  and Jhanelle E. Gray
80373-80381
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Pleiotrophin enhances PDGFB-induced gliomagenesis through increased proliferation of neural progenitor cells

Pleiotrophin enhances PDGFB-induced gliomagenesis through increased proliferation of neural progenitor cells

https://doi.org/10.18632/oncotarget.12983

Lei Zhang, Liisi Laaniste, Yiwen Jiang, Irina Alafuzoff, Lene Uhrbom,  and Anna Dimberg
80382-80390
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ANGPTL8 reverses established adriamycin cardiomyopathy by stimulating adult cardiac progenitor cells

ANGPTL8 reverses established adriamycin cardiomyopathy by stimulating adult cardiac progenitor cells

https://doi.org/10.18632/oncotarget.13061

Shuyuan Chen, Jiaxi Chen, Xing-Li Meng, Jin-Song Shen, Jing Huang, Pintong Huang, Zhaoxia Pu, Nathan H. McNeill,  and Paul A. Grayburn
80391-80403
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CARF activates beta-catenin/TCF signaling in the hepatocellular carcinoma

CARF activates beta-catenin/TCF signaling in the hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.13138

Xin Fan, Xiaoyan Ma, Lei Cui, Shengchun Dang, Jianguo Qu, Jianxin Zhang, Xuqing Wang,  and Zhengfa Mao
80404-80414
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Gli promotes epithelial-mesenchymal transition in human lung adenocarcinomas

Gli promotes epithelial-mesenchymal transition in human lung adenocarcinomas

https://doi.org/10.18632/oncotarget.11246

Hui Li, Dongsheng Yue, Joy Q. Jin, Gavitt A. Woodard, Bhairavi Tolani, Thomas M. Luh, Etienne Giroux-Leprieur, Minli Mo, Zhao Chen, Juanjuan Che, Zhenfa Zhang, Yong Zhou, Lei Wang, Xishan Hao, David Jablons, Changli Wang,  and Biao He
80415-80425
Abstract  |  PDF  |  HTML  |  Order a Reprint

Programmed death-ligand 1 expression in gastric adenocarcinoma is a poor prognostic factor in a high CD8+ tumor infiltrating lymphocytes group

Programmed death-ligand 1 expression in gastric adenocarcinoma is a poor prognostic factor in a high CD8+ tumor infiltrating lymphocytes group

https://doi.org/10.18632/oncotarget.12603

Hyeyoon Chang, Woon Yong Jung, Youngran Kang, Hyunjoo Lee, Aeree Kim, Han Kyeom Kim, Bong Kyung Shin,  and Baek-hui Kim
80426-80434
Abstract  |  PDF  |  HTML  |  Order a Reprint

SENP1 promotes proliferation of clear cell renal cell carcinoma through activation of glycolysis

SENP1 promotes proliferation of clear cell renal cell carcinoma through activation of glycolysis

https://doi.org/10.18632/oncotarget.12606

Baijun Dong, Yujing Gao, Xunlei Kang, Hongchang Gao, Jin Zhang, Hua Guo, Mingjian J You, Wei Xue, Jinke Cheng,  and Yiran Huang
80435-80449
Abstract  |  PDF  |  HTML  |  Order a Reprint

Acrolein preferentially damages nucleolus eliciting ribosomal stress and apoptosis in human cancer cells

Acrolein preferentially damages nucleolus eliciting ribosomal stress and apoptosis in human cancer cells

https://doi.org/10.18632/oncotarget.12608

Hsiang-tsui Wang, Tzu-ying Chen, Ching-wen Weng, Chun-hsiang Yang,  and Moon-shong Tang
80450-80464
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prevalence of BRCA1/BRCA2 mutations in a Brazilian population sample at-risk for hereditary breast cancer and characterization of its genetic ancestry

Prevalence of BRCA1/BRCA2 mutations in a Brazilian population sample at-risk for hereditary breast cancer and characterization of its genetic ancestry

https://doi.org/10.18632/oncotarget.12610

Gabriela C. Fernandes, Rodrigo A.D. Michelli, Henrique C.R. Galvão, André E. Paula, Rui Pereira, Carlos E. Andrade, Paula S. Felicio, Cristiano P. Souza, Deise R.P. Mendes, Sahlua Volc, Gustavo N. Berardinelli, Rebeca S. Grasel, Cristina S. Sabato, Danilo V. Viana, José Carlos Machado, José Luis Costa, Edmundo C. Mauad, Cristovam Scapulatempo-Neto, Banu Arun, Rui M. Reis,  and Edenir I. Palmero
80465-80481
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

S-nitrosation on zinc finger motif of PARP-1 as a mechanism of DNA repair inhibition by arsenite

S-nitrosation on zinc finger motif of PARP-1 as a mechanism of DNA repair inhibition by arsenite

https://doi.org/10.18632/oncotarget.12613

Xixi Zhou, Karen L. Cooper, Juliana Huestis, Huan Xu, Scott W. Burchiel, Laurie G. Hudson,  and Ke Jian Liu
80482-80492
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KIF-2C expression is correlated with poor prognosis of operable esophageal squamous cell carcinoma male patients

KIF-2C expression is correlated with poor prognosis of operable esophageal squamous cell carcinoma male patients

https://doi.org/10.18632/oncotarget.11492

Hao Duan, Xu Zhang, Fei-Xiang Wang, Mu-Yan Cai, Guo-Wei Ma, Hong Yang, Jian-Hua Fu, Zi-Hui Tan, Xia-Yu Fu, Qi-Long Ma, Xin-Ye Wang,  and Peng Lin
80493-80507
Abstract  |  PDF  |  HTML  |  Order a Reprint

A role for the vitamin D pathway in non-intestinal lesions in genetic and carcinogen models of colorectal cancer and in familial adenomatous polyposis

A role for the vitamin D pathway in non-intestinal lesions in genetic and carcinogen models of colorectal cancer and in familial adenomatous polyposis

https://doi.org/10.18632/oncotarget.12768

Yong-Sik Bong, Shahin Assefnia, Therese Tuohy, Deborah W Neklason, Randall W Burt, Jaeil Ahn, Paul J Bueno De Mesquita,  and Stephen W. Byers
80508-80520
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hypoxia promotes glioma-associated macrophage infiltration via periostin and subsequent M2 polarization by upregulating TGF-beta and M-CSFR

Hypoxia promotes glioma-associated macrophage infiltration via periostin and subsequent M2 polarization by upregulating TGF-beta and M-CSFR

https://doi.org/10.18632/oncotarget.11825

Xiaofan Guo, Hao Xue, Qianqian Shao, Jian Wang, Xing Guo, Jinsen Zhang, Shugang Xu, Tong Li, Ping Zhang, Xiao Gao, Wei Qiu, Qinglin Liu,  and Gang Li
80521-80542
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting the receptor tyrosine kinase RET in combination with aromatase inhibitors in ER positive breast cancer xenografts

Targeting the receptor tyrosine kinase RET in combination with aromatase inhibitors in ER positive breast cancer xenografts

https://doi.org/10.18632/oncotarget.11826

Elena Andreucci, Paola Francica, Antony Fearns, Lesley-Ann Martin, Paola Chiarugi, Clare M. Isacke,  and Andrea Morandi
80543-80553
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TRPC1-STIM1 activation modulates transforming growth factor β-induced epithelial-to-mesenchymal transition

TRPC1-STIM1 activation modulates transforming growth factor β-induced epithelial-to-mesenchymal transition

https://doi.org/10.18632/oncotarget.12895

Anne Schaar, Pramod Sukumaran, Yuyang Sun, Archana Dhasarathy,  and Brij B Singh
80554-80567
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Metformin enhances the radiosensitivity of human liver cancer cells to γ–rays and carbon ion beams

Metformin enhances the radiosensitivity of human liver cancer cells to γ–rays and carbon ion beams

https://doi.org/10.18632/oncotarget.12966

Eun Ho Kim, Mi-Sook Kim, Yoshiya Furusawa, Akiko Uzawa, Soorim Han, Won-Gyun Jung,  and Sei Sai
80568-80578
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Sphk1 promotes breast epithelial cell proliferation via NF-κB-p65-mediated cyclin D1 expression

Sphk1 promotes breast epithelial cell proliferation via NF-κB-p65-mediated cyclin D1 expression

https://doi.org/10.18632/oncotarget.13013

Shifei Li, Yan Zhou, Xiaodong Zheng, Xiujuan Wu, Yueyang Liang, Shushu Wang,  and Yi Zhang
80579-80585
Abstract  |  PDF  |  HTML  |  Order a Reprint

Sphingosine kinase 1 is a potential therapeutic target for nasopharyngeal carcinoma

Sphingosine kinase 1 is a potential therapeutic target for nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.13014

Wenhua Li, Jian Li, Yunchao Wang, Keqian Zhang, Ni Li, Zhiqiang Tian, Bing Ni, Huaizhi Wang,  and Zhihua Ruan
80586-80598
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting the hexosamine biosynthetic pathway and O-linked N-acetylglucosamine cycling for therapeutic and imaging capabilities in diffuse large B-cell lymphoma

Targeting the hexosamine biosynthetic pathway and O-linked N-acetylglucosamine cycling for therapeutic and imaging capabilities in diffuse large B-cell lymphoma

https://doi.org/10.18632/oncotarget.12413

Lan V. Pham, Jerry L. Bryant, Richard Mendez, Juan Chen, Archito T. Tamayo, Zijun Y. Xu-Monette, Ken H. Young, Ganiraju C. Manyam, David Yang, David Yang, L. Jeffrey Medeiros,  and Richard J. Ford
80599-80611
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The role of Pygo2 for Wnt/ß-catenin signaling activity during intestinal tumor initiation and progression

The role of Pygo2 for Wnt/ß-catenin signaling activity during intestinal tumor initiation and progression

https://doi.org/10.18632/oncotarget.13016

Suranand B. Talla,  and Felix H. Brembeck
80612-80632
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-222-3p/GNAI2/AKT axis inhibits epithelial ovarian cancer cell growth and associates with good overall survival

MicroRNA-222-3p/GNAI2/AKT axis inhibits epithelial ovarian cancer cell growth and associates with good overall survival

https://doi.org/10.18632/oncotarget.13017

Xiaodan Fu, Yimin Li, Ayesha Alvero, Juanni Li, Qihui Wu, Qing Xiao, Yulong Peng, Yongbin Hu, Xiang Li, Wenguang Yan, Ke Guo, Wenjuan Zhou, Yong Wang, Junwen Liu, Yu Zhang, Gil Mor, Jifang Wen,  and Gang Yin
80633-80654
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ERBB2 mutation is associated with a worse prognosis in patients with CDH1 altered invasive lobular cancer of the breast

ERBB2 mutation is associated with a worse prognosis in patients with CDH1 altered invasive lobular cancer of the breast

https://doi.org/10.18632/oncotarget.13019

Zheng Ping, Gene P. Siegal, Shuko Harada, Isam-Eldin Eltoum, Mariam Youssef, Tiansheng Shen, Jianbo He, Yingjie Huang, Dongquan Chen, Yiping Li, Kirby I Bland, Helena R Chang,  and Dejun Shen
80655-80663
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Integrative analysis of DNA copy number, DNA methylation and gene expression in multiple myeloma reveals alterations related to relapse

Integrative analysis of DNA copy number, DNA methylation and gene expression in multiple myeloma reveals alterations related to relapse

https://doi.org/10.18632/oncotarget.13025

Patryk Krzeminski, Luis A. Corchete, Juan L. García, Lucía López-Corral, Encarna Fermiñán, Eva M. García, Ana A. Martín, Jesús M. Hernández-Rivas, Ramón García-Sanz, Jesús F. San Miguel,  and Norma C. Gutiérrez
80664-80679
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IL-10 and PRKDC polymorphisms are associated with glioma patient survival

IL-10 and PRKDC polymorphisms are associated with glioma patient survival

https://doi.org/10.18632/oncotarget.13028

Mingjun Hu, Jieli Du, Lihong Cui, Tingqin Huang, Xiaoye Guo, Yonglin Zhao, Xudong Ma, Tianbo Jin, Gang Li,  and Jinning Song
80680-80687
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Deletion of IQGAP1 promotes Helicobacter pylori-induced gastric dysplasia in mice and acquisition of cancer stem cell properties in vitro

Deletion of IQGAP1 promotes Helicobacter pylori-induced gastric dysplasia in mice and acquisition of cancer stem cell properties in vitro

https://doi.org/10.18632/oncotarget.12486

Emilie Bessède, Silvia Molina, Luis Acuña Amador, Pierre Dubus, Cathy Staedel, Lucie Chambonnier, Alice Buissonnière, Elodie Sifré, Alban Giese, Lucie Buissonnière, Benoît Rousseau, Pierre Costet, David B. Sacks, Francis Mégraud,  and Christine Varon
80688-80699
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The CEA-/lo colorectal cancer cell population harbors cancer stem cells and metastatic cells

The CEA-/lo colorectal cancer cell population harbors cancer stem cells and metastatic cells

https://doi.org/10.18632/oncotarget.13029

Chang Yan, Yibing Hu, Bo Zhang, Lei Mu, Kaiyu Huang, Hui Zhao, Chensen Ma, Xiaolan Li, Deding Tao, Jianping Gong,  and Jichao Qin
80700-80715
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The induction of autophagy against mitochondria-mediated apoptosis in lung cancer cells by a ruthenium (II) imidazole complex

The induction of autophagy against mitochondria-mediated apoptosis in lung cancer cells by a ruthenium (II) imidazole complex

https://doi.org/10.18632/oncotarget.13032

Lanmei Chen, Guodong Li, Fa Peng, Xinming Jie, Guangzhi Dongye, Kangrong Cai, Ruibing Feng, Baojun Li, Qingwang Zeng, Kaiyi Lun, Jincan Chen,  and Bilian Xu
80716-80734
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genome-wide methylome analysis using MethylCap-seq uncovers 4 hypermethylated markers with high sensitivity for both adeno- and squamous-cell cervical carcinoma

Genome-wide methylome analysis using MethylCap-seq uncovers 4 hypermethylated markers with high sensitivity for both adeno- and squamous-cell cervical carcinoma

https://doi.org/10.18632/oncotarget.12598

Rong Wang, Robert W. van Leeuwen, Aniek Boers, Harry G. Klip, Tim de Meyer, Renske D. M. Steenbergen, Wim van Criekinge, Ate G. J. van der Zee, Ed Schuuring,  and G. Bea A. Wisman
80735-80750
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-22 targets YWHAZ to inhibit metastasis of hepatocellular carcinoma and its down-regulation predicts a poor survival

miR-22 targets YWHAZ to inhibit metastasis of hepatocellular carcinoma and its down-regulation predicts a poor survival

https://doi.org/10.18632/oncotarget.13037

Ming Chen, Wei Hu, Chen-Ling Xiong, Zhen Qu, Chang-Qing Yin, Yu-Hui Wang, Chang-Liang Luo, Qing Guan, Chun-Hui Yuan,  and Fu-Bing Wang
80751-80764
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hmgb1 inhibits Klotho expression and malignant phenotype in melanoma cells by activating NF-κB

Hmgb1 inhibits Klotho expression and malignant phenotype in melanoma cells by activating NF-κB

https://doi.org/10.18632/oncotarget.12623

Biao Xie, Ke Cao, Jinjin Li, Jia Chen, Jintian Tang, Xiang Chen, Kun Xia, Xiao Zhou, Yan Cheng, Jianda Zhou,  and Huiqing Xie
80765-80782
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Prognostic nomograms for patients with resectable hepatocelluar carcinoma incorporating systemic inflammation and tumor characteristics

Prognostic nomograms for patients with resectable hepatocelluar carcinoma incorporating systemic inflammation and tumor characteristics

https://doi.org/10.18632/oncotarget.13038

Junyi Shen, Linye He, Chuan Li, Tianfu Wen, Weixia Chen, Changli Lu, Lvnan Yan, Bo Li,  and Jiayin Yang
80783-80793
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Association of oncogenic bacteria with colorectal cancer in South China

Association of oncogenic bacteria with colorectal cancer in South China

https://doi.org/10.18632/oncotarget.13094

Youlian Zhou, Hanchang He, Haoming Xu, Yingfei Li, Zhiming Li, Yanlei Du, Jie He, Yongjian Zhou, Hong Wang,  and Yuqiang Nie
80794-80802
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Activation of PI3Kγ/Akt pathway increases cardiomyocyte HMGB1 expression in diabetic environment

Activation of PI3Kγ/Akt pathway increases cardiomyocyte HMGB1 expression in diabetic environment

https://doi.org/10.18632/oncotarget.13096

Jia Song, Qian Liu, Han Tang, Aibin Tao, Hao Wang, Raymond Kao,  and Tao Rui
80803-80810
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Association of serum 25-hydroxyvitamin D status with bone mineral density in 0-7 year old children

Association of serum 25-hydroxyvitamin D status with bone mineral density in 0-7 year old children

https://doi.org/10.18632/oncotarget.13097

Yanrong Fu, Youfang Hu, Zhenying Qin, Yan Zhao, Zi Yang, Yinfang Li, Guanyu Liang2, Heyun Lv, Hong Hong, Yuan Song, Yarong Wei, Hongni Yue, Wen Zheng, Guoqin Liu, Yufei Ni, Mei Zhu, Aiping Wu, Juhua Yan, Chenbo Ji, Xirong Guo, Juan Wen,  and Rui Qin
80811-80819
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TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TrkAIII in SH-SY5Y cells, unveiling a potential therapeutic “Achilles heel” for the TrkAIII oncoprotein in neuroblastoma

TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TrkAIII in SH-SY5Y cells, unveiling a potential therapeutic “Achilles heel” for the TrkAIII oncoprotein in neuroblastoma

https://doi.org/10.18632/oncotarget.13098

Luciana Gneo, Pierdomenico Ruggeri, Lucia Cappabianca, Antonietta Rosella Farina, Natalia Di Ianni,  and Andrew Reay Mackay
80820-80841
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Late-stage inhibition of autophagy enhances calreticulin surface exposure

Late-stage inhibition of autophagy enhances calreticulin surface exposure

https://doi.org/10.18632/oncotarget.13099

Dan-Dan Li, Bo Xie, Xiao-Jun Wu, Jing-Jing Li, Ya Ding, Xi-Zhi Wen, Xing Zhang, Shu-Guang Zhu, Wei Liu, Xiao-Shi Zhang,  and Rui-Qing Peng
80842-80854
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Pharmacological interventions for melanoma: Comparative analysis using bayesian meta-analysis

Pharmacological interventions for melanoma: Comparative analysis using bayesian meta-analysis

https://doi.org/10.18632/oncotarget.12644

Yang Yang, Jiaomiao Pei, Guozhen Gao, Zheng Yang, Shuzhong Guo, Bo Yue,  and Jianhua Qiu
80855-80871
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The components of Huang-Lian-Jie-Du-Decoction act synergistically to exert protective effects in a rat ischemic stroke model

The components of Huang-Lian-Jie-Du-Decoction act synergistically to exert protective effects in a rat ischemic stroke model

https://doi.org/10.18632/oncotarget.12645

Qian Zhang, Junsong Wang, Chao Zhang, Shanting Liao, Pei Li, Dingqiao Xu, Yan Lv, Minghua Yang,  and Lingyi Kong
80872-80887
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FoxO3a confers cetuximab resistance in RAS wild-type metastatic colorectal cancer through c-Myc

FoxO3a confers cetuximab resistance in RAS wild-type metastatic colorectal cancer through c-Myc

https://doi.org/10.18632/oncotarget.13105

Yiyi Yu, Mengzhou Guo, Ye Wei, Shan Yu, Hong Li, Yan Wang, Xiaojing Xu, Yuehong Cui, Jiawen Tian, Li Liang, Ke Peng,  and Tianshu Liu
80888-80900
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RNAi screens identify CHD4 as an essential gene in breast cancer growth

RNAi screens identify CHD4 as an essential gene in breast cancer growth

https://doi.org/10.18632/oncotarget.12646

Carolina D’Alesio, Simona Punzi, Angelo Cicalese, Lorenzo Fornasari, Laura Furia, Laura Riva, Alessandro Carugo, Giuseppe Curigliano, Carmen Criscitiello, Giancarlo Pruneri, Pier Giuseppe Pelicci, Mario Faretta, Daniela Bossi,  and Luisa Lanfrancone
80901-80915
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Karyotypic complexity rather than chromosome 8 abnormalities aggravates the outcome of chronic lymphocytic leukemia patients with TP53 aberrations

Karyotypic complexity rather than chromosome 8 abnormalities aggravates the outcome of chronic lymphocytic leukemia patients with TP53 aberrations

https://doi.org/10.18632/oncotarget.13106

Gonzalo Blanco, Anna Puiggros, Panagiotis Baliakas, Anastasia Athanasiadou, MªDolores García-Malo, Rosa Collado, Aliki Xochelli, María Rodríguez-Rivera, Margarita Ortega, Mª José Calasanz, Elisa Luño, MªTeresa Vargas, Javier Grau, Carolina Martínez-Laperche, Alberto Valiente, José Cervera, Achilles Anagnostopoulos, Eva Gimeno, Eugènia Abella, Evangelia Stalika, Jesús Mª Hernández-Rivas, Francisco José Ortuño, Diego Robles, Ana Ferrer, David Ivars, Marcos González, Francesc Bosch, Pau Abrisqueta, Kostas Stamatopoulos,  and Blanca Espinet
80916-80924
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Enrichment of C5a-C5aR axis predicts poor postoperative prognosis of patients with clear cell renal cell carcinoma

Enrichment of C5a-C5aR axis predicts poor postoperative prognosis of patients with clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.13108

Wei Xi, Li Liu, Jiajun Wang, Yu Xia, Qi Bai, Ying Xiong, Yang Qu, Qilai Long, Jiejie Xu,  and Jianming Guo
80925-80934
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic susceptibility of eight nonsynonymous polymorphisms in HLA-DRB1 gene to hepatocellular carcinoma in Han Chinese

Genetic susceptibility of eight nonsynonymous polymorphisms in HLA-DRB1 gene to hepatocellular carcinoma in Han Chinese

https://doi.org/10.18632/oncotarget.13111

Yanhui Shi, Weiyu Zhai, Bin Wang, Dongmei Zhao, He Jin, Yuefei Wang, Jidong Zhang, Hongjun An, Zhongze Fu, Kun Zhao,  and Changzhu Lu
80935-80942
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Everolimus (RAD001) sensitizes prostate cancer cells to docetaxel by down-regulation of HIF-1α and sphingosine kinase 1

Everolimus (RAD001) sensitizes prostate cancer cells to docetaxel by down-regulation of HIF-1α and sphingosine kinase 1

https://doi.org/10.18632/oncotarget.13115

Heba Alshaker, Qi Wang, Yoshiaki Kawano, Tawfiq Arafat, Torsten Böhler, Mathias Winkler, Colin Cooper,  and Dmitri Pchejetski
80943-80956
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Deregulation of small non-coding RNAs at the DLK1-DIO3 imprinted locus predicts lung cancer patient outcome

Deregulation of small non-coding RNAs at the DLK1-DIO3 imprinted locus predicts lung cancer patient outcome

https://doi.org/10.18632/oncotarget.13133

Katey S.S. Enfield, Victor D. Martinez, Erin A. Marshall, Greg L. Stewart, Sonia H.Y. Kung, Jhon R. Enterina,  and Wan L. Lam
80957-80966
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Circular RNAs and their associations with breast cancer subtypes

Circular RNAs and their associations with breast cancer subtypes

https://doi.org/10.18632/oncotarget.13134

Asha A. Nair, Nifang Niu, Xiaojia Tang, Kevin J. Thompson, Liewei Wang, Jean-Pierre Kocher, Subbaya Subramanian,  and Krishna R. Kalari
80967-80979
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dietary fibre intake and risk of breast cancer: A systematic review and meta-analysis of epidemiological studies

Dietary fibre intake and risk of breast cancer: A systematic review and meta-analysis of epidemiological studies

https://doi.org/10.18632/oncotarget.13140

Sumei Chen, Yuanyuan Chen, Shenglin Ma, Ruzhen Zheng, Pengjun Zhao, Lidan Zhang, Yuehua Liu, Qingqing Yu, Qinghua Deng,  and Ke Zhang
80980-80989
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SNHG8 is identified as a key regulator of epstein-barr virus(EBV)-associated gastric cancer by an integrative analysis of lncRNA and mRNA expression

SNHG8 is identified as a key regulator of epstein-barr virus(EBV)-associated gastric cancer by an integrative analysis of lncRNA and mRNA expression

https://doi.org/10.18632/oncotarget.13167

Tao Huang, Yan Ji, Dan Hu, Baozheng Chen, Hejun Zhang, Chao Li, Gang Chen, Xingguang Luo, Xiong-wei Zheng,  and Xiandong Lin
80990-81002
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic role of extracellular matrix metalloproteinase inducer/CD147 in gastrointestinal cancer: a meta-analysis of related studies

Prognostic role of extracellular matrix metalloproteinase inducer/CD147 in gastrointestinal cancer: a meta-analysis of related studies

https://doi.org/10.18632/oncotarget.12745

Xiaohui Huang, Weisong Shen, Weisong Shen, Hongqing Xi, Hongqing Xi, Kecheng Zhang, Kecheng Zhang, Jianxin Cui, Jianxin Cui, Bo Wei, Bo Wei, Lin Chen,  and Lin Chen
81003-81011
Abstract  |  PDF  |  HTML  |  Order a Reprint

Preclinical evaluation of the safety and pathogenicity of a live attenuated recombinant influenza A/H7N9 seed strain and corresponding MF59-adjuvanted split vaccine

Preclinical evaluation of the safety and pathogenicity of a live attenuated recombinant influenza A/H7N9 seed strain and corresponding MF59-adjuvanted split vaccine

https://doi.org/10.18632/oncotarget.12746

Huilin Ou, Wei Yao, Nanping Wu, Frederick X.C. Wang, Tianhao Weng, Chengcong Han, Xiangyun Lu, Dongshan Yu, Haibo Wu, Linfang Cheng, Honglin Chen, Hangping Yao,  and Lanjuan Li
81012-81025
Abstract  |  PDF  |  HTML  |  Order a Reprint

Nerve growth factor modulates the tumor cells migration in ovarian cancer through the WNT/β-catenin pathway

Nerve growth factor modulates the tumor cells migration in ovarian cancer through the WNT/β-catenin pathway

https://doi.org/10.18632/oncotarget.13186

Bo Li, Shaoxi Cai, Yi Zhao, Qiyi He, Xiaodong Yu, Longcong Cheng, Yingfeng Zhang, Xiancheng Hu, Ming Ke, Sijia Chen,  and Misha Zou
81026-81048
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic polymorphisms in leptin, adiponectin and their receptors affect risk and aggressiveness of prostate cancer: evidence from a meta-analysis and pooled-review

Genetic polymorphisms in leptin, adiponectin and their receptors affect risk and aggressiveness of prostate cancer: evidence from a meta-analysis and pooled-review

https://doi.org/10.18632/oncotarget.12747

Meng-Bo Hu, Hua Xu, Ji-Meng Hu, Wen-Hui Zhu, Tian Yang, Hao-Wen Jiang,  and Qiang Ding
81049-81061
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

YAP1 enhances cell proliferation, migration, and invasion of gastric cancer in vitro and in vivo

YAP1 enhances cell proliferation, migration, and invasion of gastric cancer in vitro and in vivo

https://doi.org/10.18632/oncotarget.13188

Dan Sun, Xiaoting Li, Yingjian He, Wenhui Li, Ying Wang, Huan Wang, Shanshan Jiang,  and Yan Xin
81062-81076
Abstract  |  PDF  |  HTML  |  Order a Reprint

Liraglutide suppresses obesity and induces brown fat-like phenotype via Soluble Guanylyl Cyclase mediated pathway in vivo and in vitro

Liraglutide suppresses obesity and induces brown fat-like phenotype via Soluble Guanylyl Cyclase mediated pathway in vivo and in vitro

https://doi.org/10.18632/oncotarget.13189

Endong Zhu, Yang Yang, Juanjuan Zhang, Yongmei Li, Chunjun Li, Liming Chen,  and Bei Sun
81077-81089
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Is there a benefit of first- or second-line crizotinib in locally advanced or metastatic anaplastic lymphoma kinase-positive non-small cell lung cancer? a meta-analysis

Is there a benefit of first- or second-line crizotinib in locally advanced or metastatic anaplastic lymphoma kinase-positive non-small cell lung cancer? a meta-analysis

https://doi.org/10.18632/oncotarget.13191

Hao Hu, Wei Qing Lin, Qian Zhu, Xiong Wen Yang, Hai Dong Wang,  and Yu Kang Kuang
81090-81098
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Is senescence-associated β-galactosidase a marker of neuronal senescence?

Is senescence-associated β-galactosidase a marker of neuronal senescence?

https://doi.org/10.18632/oncotarget.12752

Malgorzata Piechota, Piotr Sunderland, Adrianna Wysocka, Maria Nalberczak, Malgorzata A. Sliwinska, Kasia Radwanska,  and Ewa Sikora
81099-81109
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Inhibiting tumor necrosis factor-alpha diminishes desmoplasia and inflammation to overcome chemoresistance in pancreatic ductal adenocarcinoma

Inhibiting tumor necrosis factor-alpha diminishes desmoplasia and inflammation to overcome chemoresistance in pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.13212

Xianda Zhao, Wei Fan, Zhigao Xu, Honglei Chen, Yuyu He, Gui Yang, Gang Yang, Hanning Hu, Shihui Tang, Ping Wang, Zheng Zhang, Peipei Xu,  and Mingxia Yu
81110-81122
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Microenvironmental networks promote tumor heterogeneity and enrich for metastatic cancer stem-like cells in Luminal-A breast tumor cells

Microenvironmental networks promote tumor heterogeneity and enrich for metastatic cancer stem-like cells in Luminal-A breast tumor cells

https://doi.org/10.18632/oncotarget.13213

Polina Weitzenfeld, Tsipi Meshel,  and Adit Ben-Baruch
81123-81143
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Co-expression of Lgr5 and CXCR4 characterizes cancer stem-like cells of colorectal cancer

Co-expression of Lgr5 and CXCR4 characterizes cancer stem-like cells of colorectal cancer

https://doi.org/10.18632/oncotarget.13214

Weidong Wu, Jun Cao, Zhengyi Ji, Jingjue Wang, Tao Jiang,  and Honghua Ding
81144-81155
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Gankyrin sustains PI3K/GSK-3β/β-catenin signal activation and promotes colorectal cancer aggressiveness and progression

Gankyrin sustains PI3K/GSK-3β/β-catenin signal activation and promotes colorectal cancer aggressiveness and progression

https://doi.org/10.18632/oncotarget.13215

Feng He, Huacui Chen, Ping Yang, Qianlong Wu, Tong Zhang, Chengxing Wang, Jianchang Wei, Zhuanpeng Chen, He Hu, Wanglin Li,  and Jie Cao
81156-81171
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The combination of MLN2238 (ixazomib) with interferon-alpha results in enhanced cell death in melanoma

The combination of MLN2238 (ixazomib) with interferon-alpha results in enhanced cell death in melanoma

https://doi.org/10.18632/oncotarget.12791

Lorena P. Suarez-Kelly, Gregory M. Kemper, Megan C. Duggan, Andrew Stiff, Tiffany C. Noel, Joseph Markowitz, Eric A. Luedke, Vedat O. Yildiz, Lianbo Yu, Alena Cristina Jaime-Ramirez, Volodymyr Karpa, Xiaoli Zhang,  and William E. Carson III
81172-81186
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The genes slyA, STM3120 and htrA are required for the anticancer ability of VNP20009

The genes slyA, STM3120 and htrA are required for the anticancer ability of VNP20009

https://doi.org/10.18632/oncotarget.13217

Xiaoxin Zhang, Qiaoqiao Xu, Lirun Yang, Yueyang Lai, Zhuangzhuang Zhang, Chao Han, Chizhou Jiang, Jiahuang Li, Yixin Shi,  and Zi-Chun Hua
81187-81196
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Kinetic changes of intestinal microbiota in the course of intestinal sensitization

Kinetic changes of intestinal microbiota in the course of intestinal sensitization

https://doi.org/10.18632/oncotarget.12797

Liang Xiao, Bo Yang, Xiaoyu Liu, Yan Luo, Qiongmei Ji, Zhong Wen, Zhigang Liu,  and Ping-Chang Yang
81197-81207
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oncolytic vaccinia virus combined with radiotherapy induces apoptotic cell death in sarcoma cells by down-regulating the inhibitors of apoptosis

Oncolytic vaccinia virus combined with radiotherapy induces apoptotic cell death in sarcoma cells by down-regulating the inhibitors of apoptosis

https://doi.org/10.18632/oncotarget.12820

Michelle J. Wilkinson, Henry G. Smith, Gráinne McEntee, Joan Kyula-Currie, Tim D. Pencavel, David C. Mansfield, Aadil A. Khan, Victoria Roulstone, Andrew J. Hayes,  and Kevin J. Harrington
81208-81222
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into β-arrestin-dependent ERK signaling

Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into β-arrestin-dependent ERK signaling

https://doi.org/10.18632/oncotarget.13219

Hongda Liu, Qun Zhang, Kangshuai Li, Zheng Gong, Zhaochen Liu, Yunfei Xu, Mary Hannah Swaney, Kunhong Xiao,  and Yuxin Chen
81223-81240
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Lung tissue remodelling in MCT-induced pulmonary hypertension: a proposal for a novel scoring system and changes in extracellular matrix and fibrosis associated gene expression

Lung tissue remodelling in MCT-induced pulmonary hypertension: a proposal for a novel scoring system and changes in extracellular matrix and fibrosis associated gene expression

https://doi.org/10.18632/oncotarget.13220

Marcus Franz, Katja Grün, Stefan Betge, Ilonka Rohm, Bernadin Ndongson-Dongmo, Reinhard Bauer, P. Christian Schulze, Michael Lichtenauer, Iver Petersen, Dario Neri, Alexander Berndt,  and Christian Jung
81241-81254
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Meta-analysis of DNA methylation biomarkers in hepatocellular carcinoma

Meta-analysis of DNA methylation biomarkers in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.13221

Cheng Zhang, Jinyun Li, Tao Huang, Shiwei Duan, Dongjun Dai, Danjie Jiang, Xinbing Sui, Da Li, Yidan Chen, Fei Ding, Changxin Huang, Gongying Chen,  and Kaifeng Wang
81255-81267
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Neurokinin-1 receptor is a novel positive regulator of Wnt/ β-catenin signaling in melanogenesis

Neurokinin-1 receptor is a novel positive regulator of Wnt/ β-catenin signaling in melanogenesis

https://doi.org/10.18632/oncotarget.13222

Jia Zhou, Jingjing Ling, Huizhu Song, Bei Lv, Lei Wang, Jing Shang, Yong Wang, Chunyan Chang, Fengfeng Ping,  and Jun Qian
81268-81280
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Primary tumor microRNA signature predicts recurrence and survival in patients with locally advanced esophageal adenocarcinoma

Primary tumor microRNA signature predicts recurrence and survival in patients with locally advanced esophageal adenocarcinoma

https://doi.org/10.18632/oncotarget.12832

Daisuke Matsui, Ali H. Zaidi, Samantha A. Martin, Ashten N. Omstead, Juliann E. Kosovec, Luai Huleihel, Lindsey T. Saldin, Christina DiCarlo, Jan F. Silverman, Toshitaka Hoppo, Gene G. Finley, Stephen F. Badylak, Ronan J. Kelly,  and Blair A. Jobe
81281-81291
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The prognostic value of long non coding RNAs in non small cell lung cancer: A meta-analysis

The prognostic value of long non coding RNAs in non small cell lung cancer: A meta-analysis

https://doi.org/10.18632/oncotarget.13223

Manni Wang, Xuelei Ma, Chenjing Zhu, Linghong Guo, Qingfang Li, Ming Liu,  and Jing Zhang
81292-81304
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Signal regulatory protein α associated with the progression of oral leukoplakia and oral squamous cell carcinoma regulates phenotype switch of macrophages

Signal regulatory protein α associated with the progression of oral leukoplakia and oral squamous cell carcinoma regulates phenotype switch of macrophages

https://doi.org/10.18632/oncotarget.12874

Xiaojing Ye, Jing Zhang, Rui Lu,  and Gang Zhou
81305-81321
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p16 overexpression and 9p21 deletion are linked to unfavorable tumor phenotype in breast cancer

p16 overexpression and 9p21 deletion are linked to unfavorable tumor phenotype in breast cancer

https://doi.org/10.18632/oncotarget.13227

Patrick Lebok, Magdalena Roming, Martina Kluth, Christina Koop, Cansu Özden, Berivan Taskin, Khakan Hussein, Annette Lebeau, Isabell Witzel, Linn Wölber, Stefan Geist, Peter Paluchowski, Christian Wilke, Uwe Heilenkötter, Volkmar Müller, Barbara Schmalfeldt, Ronald Simon, Guido Sauter, Luigi Terracciano, Rainer Horst Krech, Albert von der Assen,  and Eike Burandt
81322-81331
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Twist1 promotes radioresistance in nasopharyngeal carcinoma

Twist1 promotes radioresistance in nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.12875

Linli Zhang, Beibei Su, Wei Sun, Wenwen Li, Min Luo, Dongbo Liu, Qi Mei, Guoxian Long, Guangyuan Hu,  and Guoqing Hu
81332-81340
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Squamous cell carcinomas escape immune surveillance via inducing chronic activation and exhaustion of CD8+ T Cells co-expressing PD-1 and LAG-3 inhibitory receptors

Squamous cell carcinomas escape immune surveillance via inducing chronic activation and exhaustion of CD8+ T Cells co-expressing PD-1 and LAG-3 inhibitory receptors

https://doi.org/10.18632/oncotarget.13228

Ameet K. Mishra, Tanya Kadoishi, Xiaoguang Wang, Emily Driver, Zhangguo Chen, Xiao-Jing Wang,  and Jing H. Wang
81341-81356
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Performance of multiplicom's BRCA MASTR Dx kit on the detection of BRCA1 and BRCA2 mutations in fresh frozen ovarian and breast tumor samples

Performance of multiplicom's BRCA MASTR Dx kit on the detection of BRCA1 and BRCA2 mutations in fresh frozen ovarian and breast tumor samples

https://doi.org/10.18632/oncotarget.12877

Cindy Badoer, Céline Garrec, Dirk Goossens, Gillian Ellison, John Mills, Mélina Dzial, Hakim El Housni, Sarah Berwouts, Paola Concolino, Virginie Guibert-Le Guevellou, Capucine Delnatte, Jurgen Del Favero, Ettore Capoluongo,  and Stéphane Bézieau
81357-81366
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miR-26a induced the suppression of tumor growth of cholangiocarcinoma via KRT19 approach

miR-26a induced the suppression of tumor growth of cholangiocarcinoma via KRT19 approach

https://doi.org/10.18632/oncotarget.13229

Ping Wang,  and Long Lv
81367-81376
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PC-1 works in conjunction with E3 ligase CHIP to regulate androgen receptor stability and activity

PC-1 works in conjunction with E3 ligase CHIP to regulate androgen receptor stability and activity

https://doi.org/10.18632/oncotarget.13230

Jian Wang, Hui Zhang, Xiaoqing Zhang, Peng Wang, Hongtao Wang, Fang Huang, Chenyan Zhou, Jianguang Zhou,  and Shanhu Li
81377-81388
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Incorporation of alpha-fetoprotein(AFP) into subclassification of BCLC C stage hepatocellular carcinoma according to a 5-year survival analysis based on the SEER database

Incorporation of alpha-fetoprotein(AFP) into subclassification of BCLC C stage hepatocellular carcinoma according to a 5-year survival analysis based on the SEER database

https://doi.org/10.18632/oncotarget.13232

Nan Zhang, Jiajia Gu, Li Yin, Jing Wu, Ming-yu Du, Kai Ding, Teng Huang,  and Xia He
81389-81401
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Anti-EGFR antibody sensitizes colorectal cancer stem-like cells to Fluorouracil-induced apoptosis by affecting autophagy

Anti-EGFR antibody sensitizes colorectal cancer stem-like cells to Fluorouracil-induced apoptosis by affecting autophagy

https://doi.org/10.18632/oncotarget.13233

Ye Feng, Shuohui Gao, Yongjian Gao, Xuefeng Wang,  and Zhi Chen
81402-81409
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Long noncoding RNA BX357664 regulates cell proliferation and epithelial-to-mesenchymal transition via inhibition of TGF-β1/p38/HSP27 signaling in renal cell carcinoma

Long noncoding RNA BX357664 regulates cell proliferation and epithelial-to-mesenchymal transition via inhibition of TGF-β1/p38/HSP27 signaling in renal cell carcinoma

https://doi.org/10.18632/oncotarget.12937

Yiyang Liu, Jian Qian, Xiao Li, Wei Chen, Aiming Xu, Kai Zhao, Yibo Hua, Zhengkai Huang, Jianzhong Zhang, Chao Liang, Shifeng Su, Pu Li, Pengfei Shao, Jie Li, Chao Qin,  and Zengjun Wang
81410-81422
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Dapper homolog 1 alpha suppresses metastasis ability of gastric cancer through inhibiting planar cell polarity pathway

Dapper homolog 1 alpha suppresses metastasis ability of gastric cancer through inhibiting planar cell polarity pathway

https://doi.org/10.18632/oncotarget.13234

Yuegeng Liu, Jingwan Zhang, Weifang Yu, Xiaoming Zhang, Guiqi Wang,  and Zengren Zhao
81423-81434
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Systematic approach identifies RHOA as a potential biomarker therapeutic target for Asian gastric cancer

Systematic approach identifies RHOA as a potential biomarker therapeutic target for Asian gastric cancer

https://doi.org/10.18632/oncotarget.12963

Hae Ryung Chang, Seungyoon Nam, Jinhyuk Lee, Jin-Hee Kim, Hae Rim Jung, Hee Seo Park, Sungjin Park, Young Zoo Ahn, Iksoo Huh, Curt Balch, Ja-Lok Ku, Garth Powis, Taesung Park, Jin-Hyun Jeong,  and Yon Hui Kim
81435-81451
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LncRNA H19 confers chemoresistance in ERα-positive breast cancer through epigenetic silencing of the pro-apoptotic gene BIK

LncRNA H19 confers chemoresistance in ERα-positive breast cancer through epigenetic silencing of the pro-apoptotic gene BIK

https://doi.org/10.18632/oncotarget.13263

Xinxin Si, Ruochen Zang, Erbao Zhang, Yue Liu, Xiao Shi, Ershao Zhang, Lipei Shao, Andi Li, Nan Yang, Xiao Han, Beijing Pan, Zhihong Zhang, Luan Sun,  and Yujie Sun
81452-81462
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Ubiquitin-like protein FAT10 promotes bladder cancer progression by stabilizing survivin

Ubiquitin-like protein FAT10 promotes bladder cancer progression by stabilizing survivin

https://doi.org/10.18632/oncotarget.12976

Dingxiang Dong, Weifan Jiang, Jun Lei, Leifeng Chen, Xiuxia Liu, Jin Ge, Ben Che, Xiaoqing Xi,  and Jianghua Shao
81463-81473
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TWEAK activation of the non-canonical NF-κB signaling pathway differentially regulates melanoma and prostate cancer cell invasion

TWEAK activation of the non-canonical NF-κB signaling pathway differentially regulates melanoma and prostate cancer cell invasion

https://doi.org/10.18632/oncotarget.13034

Cheryl L. Armstrong, Rebeca Galisteo, Sharron A.N. Brown,  and Jeffrey A. Winkles
81474-81492
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The evaluation of immunotherapy and chemotherapy treatment on melanoma: a network meta-analysis

The evaluation of immunotherapy and chemotherapy treatment on melanoma: a network meta-analysis

https://doi.org/10.18632/oncotarget.13277

BaSang CiRen, Xinhua Wang,  and Ziwen Long
81493-81511
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TET2 functions as a resistance factor against DNA methylation acquisition during Epstein-Barr virus infection

TET2 functions as a resistance factor against DNA methylation acquisition during Epstein-Barr virus infection

https://doi.org/10.18632/oncotarget.13130

Hiroe Namba-Fukuyo, Sayaka Funata, Keisuke Matsusaka, Masaki Fukuyo, Bahityar Rahmutulla, Yasunobu Mano, Masashi Fukayama, Hiroyuki Aburatani,  and Atsushi Kaneda
81512-81526
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Knockdown of TRIM65 inhibits lung cancer cell proliferation, migration and invasion: A therapeutic target in human lung cancer

Knockdown of TRIM65 inhibits lung cancer cell proliferation, migration and invasion: A therapeutic target in human lung cancer

https://doi.org/10.18632/oncotarget.13131

Xiao-Lin Wang, Wei-Ping Shi, Hong-Can Shi1, Shi-Chun Lu, Kang Wang, Chao Sun, Jian-Sheng He, Wei-Guo Jin, Xiao-Xia Lv, Hui Zou,  and Yu-Sheng Shu
81527-81540
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Post-transcriptional regulation of 5'-untranslated regions of human Transient Receptor Potential Vanilloid type-1 (TRPV-1) channels: role in the survival of glioma patients

Post-transcriptional regulation of 5'-untranslated regions of human Transient Receptor Potential Vanilloid type-1 (TRPV-1) channels: role in the survival of glioma patients

https://doi.org/10.18632/oncotarget.13132

Massimo Nabissi, Maria Beatrice Morelli, Antonietta Arcella, Claudio Cardinali, Matteo Santoni, Giovanni Bernardini, Angela Santoni, Giorgio Santoni,  and Consuelo Amantini
81541-81554
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Celecoxib inhibits proliferation and survival of chronic myelogeous leukemia (CML) cells via AMPK-dependent regulation of β-catenin and mTORC1/2

Celecoxib inhibits proliferation and survival of chronic myelogeous leukemia (CML) cells via AMPK-dependent regulation of β-catenin and mTORC1/2

https://doi.org/10.18632/oncotarget.13146

Beatrice Riva, Marco De Dominici, Ilaria Gnemmi, Samanta A. Mariani, Alberto Minassi, Valentina Minieri, Paolo Salomoni, Pier Luigi Canonico, Armando A. Genazzani, Bruno Calabretta,  and Fabrizio Condorelli
81555-81570
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Epigenetic upregulation of ARL4C, due to DNA hypomethylation in the 3'-untranslated region, promotes tumorigenesis of lung squamous cell carcinoma

Epigenetic upregulation of ARL4C, due to DNA hypomethylation in the 3'-untranslated region, promotes tumorigenesis of lung squamous cell carcinoma

https://doi.org/10.18632/oncotarget.13147

Shinsuke Fujii, Keiko Shinjo, Shinji Matsumoto, Takeshi Harada, Satoshi Nojima, Sunao Sato, Yu Usami, Satoru Toyosawa, Eiichi Morii, Yutaka Kondo,  and Akira Kikuchi
81571-81587
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Orai3 is a predictive marker of metastasis and survival in resectable lung adenocarcinoma

Orai3 is a predictive marker of metastasis and survival in resectable lung adenocarcinoma

https://doi.org/10.18632/oncotarget.13149

Nazim Benzerdjeb, Henri Sevestre, Ahmed Ahidouch,  and Halima Ouadid-Ahidouch
81588-81597
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Characterization of osimertinib (AZD9291)-resistant non-small cell lung cancer NCI-H1975/OSIR cell line

Characterization of osimertinib (AZD9291)-resistant non-small cell lung cancer NCI-H1975/OSIR cell line

https://doi.org/10.18632/oncotarget.13150

Zheng-Hai Tang, Xiao-Ming Jiang, Xia Guo, Chi Man Vivienne Fong, Xiuping Chen,  and Jin-Jian Lu
81598-81610
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Prognostic nutritional index predicts short-term outcomes after liver resection for hepatocellular carcinoma within the Milan criteria

Prognostic nutritional index predicts short-term outcomes after liver resection for hepatocellular carcinoma within the Milan criteria

https://doi.org/10.18632/oncotarget.13151

Mengyun Ke, Tao Xu, Na Li, Yifan Ren, Aihua Shi, Yi Lv,  and Haiqi He
81611-81620
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miRNA-200a/c as potential biomarker in epithelial ovarian cancer (EOC): evidence based on miRNA meta-signature and clinical investigations

miRNA-200a/c as potential biomarker in epithelial ovarian cancer (EOC): evidence based on miRNA meta-signature and clinical investigations

https://doi.org/10.18632/oncotarget.13154

Yue Teng, Xuan Su, Xing Zhang, Yan Zhang, Chen Li, Wenquan Niu, Chang Liu,  and Kai Qu
81621-81633
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AEG-1 knockdown in colon cancer cell lines inhibits radiation-enhanced migration and invasion in vitro and in a novel in vivo zebrafish model

AEG-1 knockdown in colon cancer cell lines inhibits radiation-enhanced migration and invasion in vitro and in a novel in vivo zebrafish model

https://doi.org/10.18632/oncotarget.13155

Sebastian Gnosa, Alessandra Capodanno, Raghavendra Vasudeva Murthy, Lasse Dahl Ejby Jensen,  and Xiao-Feng Sun
81634-81644
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Sprouty2 inhibits amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells

Sprouty2 inhibits amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells

https://doi.org/10.18632/oncotarget.13162

Jung-Chien Cheng, Hsun-Ming Chang, Siyuan Xiong, Wai-Kin So,  and Peter C. K. Leung
81645-81660
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The associations between mast cell infiltration, clinical features and molecular types of invasive breast cancer

The associations between mast cell infiltration, clinical features and molecular types of invasive breast cancer

https://doi.org/10.18632/oncotarget.13163

Jianfeng Sang, Dandan Yi, Xiaoqiao Tang, Yifen Zhang,  and Tao Huang
81661-81669
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Identification of a seven-miRNA signature as prognostic biomarker for lung squamous cell carcinoma

Identification of a seven-miRNA signature as prognostic biomarker for lung squamous cell carcinoma

https://doi.org/10.18632/oncotarget.13164

Xujie Gao, Yupeng Wu, Wenwen Yu,  and Hui Li
81670-81679
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Prediction of the risk of mortality using risk score in patients with coronary heart disease

Prediction of the risk of mortality using risk score in patients with coronary heart disease

https://doi.org/10.18632/oncotarget.13166

Qian Chen, Ding Ding, Yuan Zhang, Yunou Yang, Qing Li, Xuechen Chen, Gang Hu,  and Wenhua Ling
81680-81690
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A functional variant rs4442975 modulating FOXA1-binding affinity does not influence the risk or progression of breast cancer in Chinese Han population

A functional variant rs4442975 modulating FOXA1-binding affinity does not influence the risk or progression of breast cancer in Chinese Han population

https://doi.org/10.18632/oncotarget.13168

Yi Zhang, Yan Li, Shaojie Jiang, Wei Chen, Jiao Lou, Juntao Ke, Jiaoyuan Li, Ying Zhu, Yajie Gong, Yang Yang, Jianbo Tian, Xiating Peng, Danyi Zou, Jing Gong, Jiang Chang, Xiaoping Miao,  and Rong Zhong
81691-81697
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Regulatory landscape and clinical implication of MBD3 in human malignant glioma

Regulatory landscape and clinical implication of MBD3 in human malignant glioma

https://doi.org/10.18632/oncotarget.13173

Yi Cui, Jian Li, Ling Weng, Sara E. Wirbisky, Jennifer L. Freeman, Jingping Liu, Qing Liu, Xianrui Yuan,  and Joseph Irudayaraj
81698-81714
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Integrated bioinformatics analysis of chromatin regulator EZH2 in regulating mRNA and lncRNA expression by ChIP sequencing and RNA sequencing

Integrated bioinformatics analysis of chromatin regulator EZH2 in regulating mRNA and lncRNA expression by ChIP sequencing and RNA sequencing

https://doi.org/10.18632/oncotarget.13169

Yuan Li, Mei Luo, Xuejiao Shi, Zhiliang Lu, Shouguo Sun, Jianbing Huang, Zhaoli Chen,  and Jie He
81715-81726
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KY1022, a small molecule destabilizing Ras via targeting the Wnt/β-catenin pathway, inhibits development of metastatic colorectal cancer

KY1022, a small molecule destabilizing Ras via targeting the Wnt/β-catenin pathway, inhibits development of metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.13172

Yong-Hee Cho, Pu-Hyun Cha, Saluja Kaduwal, Jong-Chan Park, Sang-Kyu Lee, Jeong-Su Yoon, Wookjin Shin, Hyuntae Kim, Eun Ji Ro, Kyung- Hwa Koo, Ki-Sook Park, Gyoonhee Han,  and Kang-Yell Choi
81727-81740
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Multi-modality imaging to assess metabolic response to dichloroacetate treatment in tumor models

Multi-modality imaging to assess metabolic response to dichloroacetate treatment in tumor models

https://doi.org/10.18632/oncotarget.13176

Marie-Aline Neveu, Géraldine De Preter, Nicolas Joudiou, Anne Bol, Jeffery R. Brender, Keita Saito, Shun Kishimoto, Vincent Grégoire, Bénédicte F. Jordan, Murali C. Krishna, Olivier Feron,  and Bernard Gallez
81741-81749
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Overexpression of B7-H3 correlates with aggressive clinicopathological characteristics in non-small cell lung cancer

Overexpression of B7-H3 correlates with aggressive clinicopathological characteristics in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.13177

Shanshan Wu, Xiangfei Zhao, Sudong Wu, Rui Du, Qi Zhu, Henghu Fang, Xinhong Zhang, Chunyang Zhang, Wei Zheng, Jihua Yang,  and Huasong Feng
81750-81756
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Transcriptional repression of FOXO1 by KLF4 contributes to glioma progression

Transcriptional repression of FOXO1 by KLF4 contributes to glioma progression

https://doi.org/10.18632/oncotarget.13184

Guodong Tang, Dingyang Liu, Gelei Xiao, Qing Liu,  and Jian Yuan
81757-81767
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Non-invasive diagnosis of papillary thyroid microcarcinoma: a NMR-based metabolomics approach

Non-invasive diagnosis of papillary thyroid microcarcinoma: a NMR-based metabolomics approach

https://doi.org/10.18632/oncotarget.13178

Jinghui Lu, Sanyuan Hu, Paolo Miccoli, Qingdong Zeng, Shaozhuang Liu, Lin Ran,  and Chunxiao Hu
81768-81777
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Immunoscore encompassing CD3+ and CD8+ T cell densities in distant metastasis is a robust prognostic marker for advanced colorectal cancer

Immunoscore encompassing CD3+ and CD8+ T cell densities in distant metastasis is a robust prognostic marker for advanced colorectal cancer

https://doi.org/10.18632/oncotarget.13207

Yoonjin Kwak, Jiwon Koh, Duck Woo Kim, Sung Bum Kang, Woo Ho Kim,  and Hye Seung Lee
81778-81790
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Tuftsin prevents the negative immunoregulation of neuropilin-1highCD4+CD25+Regulatory T cells and improves survival rate in septic mice

Tuftsin prevents the negative immunoregulation of neuropilin-1highCD4+CD25+Regulatory T cells and improves survival rate in septic mice

https://doi.org/10.18632/oncotarget.13235

Yu-Lei Gao, Mu-Ming Yu, Song-Tao Shou, Ying Yao, Yan-Cun Liu, Li-Jun Wang, Bin Lu,  and Yan-Fen Chai
81791-81805
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Knockdown of long non-coding RNA CCAT2 suppressed proliferation and migration of glioma cells

Knockdown of long non-coding RNA CCAT2 suppressed proliferation and migration of glioma cells

https://doi.org/10.18632/oncotarget.13242

Hua Guo, Qing Yang, Guowen Hu, Pei Zhang, Wei Kuang, Xingen Zhu,  and Lei Wu
81806-81814
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TTK is a favorable prognostic biomarker for triple-negative breast cancer survival

TTK is a favorable prognostic biomarker for triple-negative breast cancer survival

https://doi.org/10.18632/oncotarget.13245

Qianqian Xu, Yali Xu, Bo Pan, Liangcai Wu, Xinyu Ren, Yidong Zhou, Feng Mao, Yan Lin, Jinghong Guan, Songjie Shen, Xiaohui Zhang, Changjun Wang, Ying Zhong, Liangrui Zhou, Zhiyong Liang, Haitao Zhao,  and Qiang Sun
81815-81829
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Clinicopathological and prognostic significance of platelet-to-lymphocyte ratio in patients with hepatocellular carcinoma

Clinicopathological and prognostic significance of platelet-to-lymphocyte ratio in patients with hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.13244

Wei Song, Kai Wang, Fu-ping Zhong, You-wen Fan, Lang Peng,  and Shu-bing Zou
81830-81838
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Comparative study of single-nucleotide polymorphism array and next generation sequencing based strategies on triploid identification in preimplantation genetic diagnosis and screen

Comparative study of single-nucleotide polymorphism array and next generation sequencing based strategies on triploid identification in preimplantation genetic diagnosis and screen

https://doi.org/10.18632/oncotarget.13247

Jiawei Xu, Wenbin Niu, Zhaofeng Peng, Xiao Bao, Meixiang Zhang, Linlin Wang, Linqing Du, Nan Zhang,  and Yingpu Sun
81839-81848
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Prognostic significance of pretreatment elevated platelet count in patients with colorectal cancer: a meta-analysis

Prognostic significance of pretreatment elevated platelet count in patients with colorectal cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.13248

Yu Long, Ting Wang, Qian Gao,  and Chengya Zhou
81849-81861
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Growth hormone replacement therapy reduces risk of cancer in adult with growth hormone deficiency: A meta-analysis

Growth hormone replacement therapy reduces risk of cancer in adult with growth hormone deficiency: A meta-analysis

https://doi.org/10.18632/oncotarget.13251

Zhanzhan Li, Qin Zhou, Yanyan Li, Jun Fu, Xinqiong Huang,  and Liangfang Shen
81862-81869
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Impact of HLA-B*58:01 allele and allopurinol-induced cutaneous adverse drug reactions: evidence from 21 pharmacogenetic studies

Impact of HLA-B*58:01 allele and allopurinol-induced cutaneous adverse drug reactions: evidence from 21 pharmacogenetic studies

https://doi.org/10.18632/oncotarget.13250

Ran Wu, Yi-ju Cheng, Li-li Zhu, Lei Yu, Xue-ke Zhao, Min Jia, Chang-hui Wen, Xing-zhen Long, Ting Tang, Ai-juan He, Yi-yan Zeng, Zun-feng Ma, Zhi Zheng, Mu-zi Ni,  and Gong-jing Cai
81870-81879
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Clinical Research Papers

Determining the optimal 5-FU therapeutic dosage in the treatment of colorectal cancer patients

Determining the optimal 5-FU therapeutic dosage in the treatment of colorectal cancer patients

https://doi.org/10.18632/oncotarget.11980

Ling Fang, Yi Jiang, Yuxian Yang, Yuqiong Zheng, Jin Zheng, Hong Jiang, Shengqi Zhang, Lifang Lin, Jieting Zheng, Shuyao Zhang,  and Xiaowen Zhuang
81880-81887
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Accelerated whole breast irradiation in early breast cancer patients with adverse prognostic features

Accelerated whole breast irradiation in early breast cancer patients with adverse prognostic features

https://doi.org/10.18632/oncotarget.11702

Sea-Won Lee, Kyung Hwan Shin, Eui Kyu Chie, Jin Ho Kim, Seock-Ah Im, Wonshik Han, Dong-Young Noh, Hyeon Woo Lim, Tae Hyun Kim, Keun Seok Lee, Eun Sook Lee, Soo Yoon Sung,  and Kyubo Kim
81888-81898
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical outcome of intensity modulated radiotherapy for carcinoma showing thymus-like differentiation

Clinical outcome of intensity modulated radiotherapy for carcinoma showing thymus-like differentiation

https://doi.org/10.18632/oncotarget.11914

Fangfang Kong, Hongmei Ying, Ruiping Zhai, Chengrun Du, Shuang Huang, Junjun Zhou, Xiayun He, Chaosu Hu, Zhuoying Wang, Tuanqi Sun,  and Qinghai Ji
81899-81905
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Risk factors of brain metastasis during the course of EGFR-TKIs therapy for patients with EGFR-mutated advanced lung adenocarcinoma

Risk factors of brain metastasis during the course of EGFR-TKIs therapy for patients with EGFR-mutated advanced lung adenocarcinoma

https://doi.org/10.18632/oncotarget.11918

Xiaoyan Ma, Hui Zhu, Hongbo Guo, Anqin Han, Haiyong Wang, Wang Jing, Yan Zhang, Li Kong,  and Jinming Yu
81906-81917
Abstract  |  PDF  |  HTML  |  Order a Reprint

T4/N2 classification nasopharyngeal carcinoma benefit from concurrent chemotherapy in the era of intensity-modulated radiotherapy

T4/N2 classification nasopharyngeal carcinoma benefit from concurrent chemotherapy in the era of intensity-modulated radiotherapy

https://doi.org/10.18632/oncotarget.11981

Ruifei Xie, Bing Xia, Xuebang Zhang, Wei Hu, Ruping Zhao, Congying Xie, Jianhua Wang Jianhua Wang, Ni Zhang,  and Shixiu Wu
81918-81925
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Reviews

Kinase inhibitors as potential agents in the treatment of multiple myeloma

Kinase inhibitors as potential agents in the treatment of multiple myeloma

https://doi.org/10.18632/oncotarget.10745

Hanley N. Abramson
81926-81968
Abstract  |  PDF  |  HTML  |  Order a Reprint

Case Reports

Multiple primary lung cancer displaying different EGFR and PTEN molecular profiles

Multiple primary lung cancer displaying different EGFR and PTEN molecular profiles

https://doi.org/10.18632/oncotarget.13046

Zhouyu Zhu, Tao Yu,  and Ying Chai
81969-81971
Abstract  |  PDF  |  HTML  |  Order a Reprint

Corrections

Correction: A novel small molecule agent displays potent anti-myeloma activity by inhibiting the JAK2-STAT3 signaling pathway

Correction: A novel small molecule agent displays potent anti-myeloma activity by inhibiting the JAK2-STAT3 signaling pathway

https://doi.org/10.18632/oncotarget.13803

Zubin Zhang, Hongwu Mao, Xiaolin Du, Jingyu Zhu, Yujia Xu, Siyu Wang, Xin Xu, Peng Ji, Yang Yu, Biyin Cao, Kunkun Han, Tingjun Hou, Zhuan Xu, Yan Kong, Gaofeng Jiang, Xiaowen Tang, Chunhua Qiao,  and Xinliang Mao
81972-81972
Correction  |  PDF


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