Oncotarget

Vol 7, No 47

November 22, 2016

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About The Cover

The cover for issue 47 of Oncotarget features Figure 6B, 'Effect of E542K and E545K mutations on LY414 binding to PI3K,' from Wei, et al.

Table of Contents

Research Perspective: Immunology

Therapeutic effect of erythroid differentiation regulator 1 (Erdr1) on collagen-induced arthritis in DBA/1J mouse

Therapeutic effect of erythroid differentiation regulator 1 (Erdr1) on collagen-induced arthritis in DBA/1J mouse

https://doi.org/10.18632/oncotarget.13047

Kyung Eun Kim, Sungryung Kim, Sunyoung Park, Younkyung Houh, Yoolhee Yang, Seung Beom Park, Sangyoon Kim, Daejin Kim, Dae Young Hur, Seonghan Kim, Hyun Jeong Park, Sa Ik Bang,  and Daeho Cho
76354-76361
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Priority Research Papers

Clinical outcomes based on multigene profiling in metastatic breast cancer patients

Clinical outcomes based on multigene profiling in metastatic breast cancer patients

https://doi.org/10.18632/oncotarget.12987

Reva K. Basho, Debora de Melo Gagliato, Naoto T. Ueno, Chetna Wathoo, Huiqin Chen, Maryam Shariati, Caimiao Wei, Ricardo H. Alvarez, Stacy L. Moulder, Aysegul A. Sahin, Sinchita Roy-Chowdhuri, Mariana Chavez-MacGregor, Jennifer K. Litton, Vincent Valero, Raja Luthra, Jia Zeng, Kenna R. Shaw, John Mendelsohn, Gordon B. Mills, Debu Tripathy,  and Funda Meric-Bernstam
76362-76373
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Genomic profiling is predictive of response to cisplatin treatment but not to PI3K inhibition in bladder cancer patient-derived xenografts

Genomic profiling is predictive of response to cisplatin treatment but not to PI3K inhibition in bladder cancer patient-derived xenografts

https://doi.org/10.18632/oncotarget.13062

Lei Wei, Sreenivasulu Chintala, Eric Ciamporcero, Swathi Ramakrishnan, May Elbanna, Jianmin Wang, Qiang Hu, Sean T. Glenn, Mitsuko Murakami, Lu Liu, Eduardo Cortes Gomez, Yuchen Sun, Jacob Conroy, Kiersten Marie Miles, Kullappan Malathi, Sudha Ramaiah, Anand Anbarasu, Anna Woloszynska-Read, Candace S. Johnson, Jeffrey Conroy, Song Liu, Carl D. Morrison,  and Roberto Pili
76374-76389
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Research Papers: Gerotarget (Focus on Aging)

Age-related decline in cardiac autonomic function is not attenuated with increased physical activity

Age-related decline in cardiac autonomic function is not attenuated with increased physical activity

https://doi.org/10.18632/oncotarget.12403

Hugo Njemanze, Charlotte Warren, Christopher Eggett, Guy A. MacGowan, Matthew G.D. Bates, Mario Siervo, Srdjan Ivkovic, Michael I. Trenell,  and Djordje G. Jakovljevic
76390-76397
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Research Papers: Pathology

Mitochondrial aldehyde dehydrogenase obliterates insulin resistance-induced cardiac dysfunction through deacetylation of PGC-1α

Mitochondrial aldehyde dehydrogenase obliterates insulin resistance-induced cardiac dysfunction through deacetylation of PGC-1α

https://doi.org/10.18632/oncotarget.11977

Nan Hu, Jun Ren,  and Yingmei Zhang
76398-76414
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Clinical and immunohistochemical characteristics of type II and type I focal cortical dysplasia

Clinical and immunohistochemical characteristics of type II and type I focal cortical dysplasia

https://doi.org/10.18632/oncotarget.13001

Kun Yao, Zejun Duan, Jian Zhou, Lin Li, Feng Zhai, Yanting Dong, Xiaoyan Wang, Zhong Ma, Yu Bian, Xueling Qi,  and Liang Li
76415-76422
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Tet methylcytosine dioxygenase 2 inhibits atherosclerosis via upregulation of autophagy in ApoE−/− mice

Tet methylcytosine dioxygenase 2 inhibits atherosclerosis via upregulation of autophagy in ApoE−/− mice

https://doi.org/10.18632/oncotarget.13121

Juan Peng, Qin Yang, A-Fang Li, Rong-Qing Li, Zuo Wang, Lu-Shan Liu, Zhong Ren, Xi-Long Zheng, Xiao-Qing Tang, Guo-Hua Li, Zhi-Han Tang, Zhi-Sheng Jiang,  and Dang-Heng Wei
76423-76436
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Stimulus-dependent dissociation between XB130 and Tks5 scaffold proteins promotes airway epithelial cell migration

Stimulus-dependent dissociation between XB130 and Tks5 scaffold proteins promotes airway epithelial cell migration

https://doi.org/10.18632/oncotarget.13261

Serisha Moodley, Mathieu Derouet, Xiao Hui Bai, Feng Xu, Andras Kapus, Burton B. Yang,  and Mingyao Liu
76437-76452
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Research Papers: Immunology

The aberrant expression of microRNAs and correlations with T cell subsets in patients with immune thrombocytopenia

The aberrant expression of microRNAs and correlations with T cell subsets in patients with immune thrombocytopenia

https://doi.org/10.18632/oncotarget.12949

Lu Liu, Mingqiang Hua, Chuanfang Liu, Na He, Zhao Li,  and Daoxin Ma
76453-76463
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The association between expression of IFIT1 in podocytes of MRL/lpr mice and the renal pathological changes it causes: An animal study

The association between expression of IFIT1 in podocytes of MRL/lpr mice and the renal pathological changes it causes: An animal study

https://doi.org/10.18632/oncotarget.13045

Weiping Hu, Guodong Niu, Hongbo Li, Hanyuan Gao, Rudian Kang, Xiaoqing Chen,  and Ling Lin
76464-76470
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Effect of cobalt-mediated Toll-like receptor 4 activation on inflammatory responses in endothelial cells

Effect of cobalt-mediated Toll-like receptor 4 activation on inflammatory responses in endothelial cells

https://doi.org/10.18632/oncotarget.13260

Sami A. Anjum, Helen Lawrence, James P. Holland, John A. Kirby, David J. Deehan,  and Alison J. Tyson-Capper
76471-76478
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Roles of calpain-calpastatin system (CCS) in human T cell activation

Roles of calpain-calpastatin system (CCS) in human T cell activation

https://doi.org/10.18632/oncotarget.13259

Anna Mikosik, Aleksandra Jasiulewicz, Agnieszka Daca, Izabella Henc, Joanna E. Frąckowiak, Katarzyna Ruckemann-Dziurdzińska, Jerzy Foerster, Aurelie Le Page, Ewa Bryl, Tamas Fulop,  and Jacek M. Witkowski
76479-76495
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Research Papers: Autophagy and Cell Death

Apoptosis inducing factor (AIF) mediates lethal redox stress induced by menadione

Apoptosis inducing factor (AIF) mediates lethal redox stress induced by menadione

https://doi.org/10.18632/oncotarget.12562

Hesti Lina Wiraswati, Emilie Hangen, Ana Belén Sanz, Ngoc-Vy Lam, Camille Reinhardt, Allan Sauvat, Ariane Mogha, Alberto Ortiz, Guido Kroemer,  and Nazanine Modjtahedi
76496-76507
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Dihydromyricetin protects against liver ischemia/reperfusion induced apoptosis via activation of FOXO3a-mediated autophagy

Dihydromyricetin protects against liver ischemia/reperfusion induced apoptosis via activation of FOXO3a-mediated autophagy

https://doi.org/10.18632/oncotarget.12894

Yongbiao Chen, Lizhi Lv, Huifeng Pi, Weijia Qin, Jianwei Chen, Dengfang Guo, Jianyu Lin, Xiaobing Chi, Zhelong Jiang, Hejun Yang,  and Yi Jiang
76508-76522
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Research Papers

Prognostic role of high B7-H4 expression in patients with solid tumors: a meta-analysis

Prognostic role of high B7-H4 expression in patients with solid tumors: a meta-analysis

https://doi.org/10.18632/oncotarget.8598

Xing Song, Yingjie Shao, Wendong Gu, Chao Xu, Huihui Mao, Honglei Pei,  and Jingting Jiang
76523-76533
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Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition

Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition

https://doi.org/10.18632/oncotarget.12266

Junko Murai, Ying Feng, Guoying K. Yu, Yuanbin Ru, Sai-Wen Tang, Yuqiao Shen,  and Yves Pommier
76534-76550
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Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer

Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer

https://doi.org/10.18632/oncotarget.10388

Liyuan Zhang, Zhenlong Yu, Yan Wang, Xiaobo Wang, Lianru Zhang, Chao Wang, Qingxi Yue, Xun Wang, Sa Deng, Xiaokui Huo, Xiangge Tian, Shanshan Huang, Baojing Zhang,  and Xiaochi Ma
76551-76564
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Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors

Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors

https://doi.org/10.18632/oncotarget.12088

Yu Mei, Wenya Linda Bi, Noah F. Greenwald, Ziming Du, Nathalie Y.R. Agar, Ursula B. Kaiser, Whitney W. Woodmansee, David A. Reardon, Gordon J. Freeman, Peter E. Fecci, Edward R. Laws Jr, Sandro Santagata, Gavin P. Dunn,  and Ian F. Dunn
76565-76576
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Dasatinib modulates sensitivity to pemetrexed in malignant pleural mesothelioma cell lines

Dasatinib modulates sensitivity to pemetrexed in malignant pleural mesothelioma cell lines

https://doi.org/10.18632/oncotarget.10428

Valentina Monica, Marco Lo Iacono, Enrico Bracco, Simone Busso, Laura Di Blasio, Luca Primo, Barbara Peracino, Mauro Papotti,  and Giorgio Scagliotti
76577-76589
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Reduced PAK1 activity sensitizes FA/BRCA-proficient breast cancer cells to PARP inhibition

Reduced PAK1 activity sensitizes FA/BRCA-proficient breast cancer cells to PARP inhibition

https://doi.org/10.18632/oncotarget.12576

Olga Villamar, Tatiana Y. Prudnikova, Daniela Araiza-Olivera, Carlos Perez-Plasencia, Neil Johnson, Andrea J. Bernhardy, Michael Slifker, Catherine Renner, Jonathan Chernoff,  and Luis E. Arias-Romero
76590-76603
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Soluble programmed death-ligand 1 (sPDL1) and neutrophil-to-lymphocyte ratio (NLR) predicts survival in advanced biliary tract cancer patients treated with palliative chemotherapy

Soluble programmed death-ligand 1 (sPDL1) and neutrophil-to-lymphocyte ratio (NLR) predicts survival in advanced biliary tract cancer patients treated with palliative chemotherapy

https://doi.org/10.18632/oncotarget.12810

Hyerim Ha, Ah-Rong Nam, Ju-Hee Bang, Ji-Eun Park, Tae-Yong Kim, Kyung-Hun Lee, Sae-Won Han, Seock-Ah Im, Tae-You Kim, Yung-Jue Bang,  and Do-Youn Oh
76604-76612
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Low dose angiostatic treatment counteracts radiotherapy-induced tumor perfusion and enhances the anti-tumor effect

Low dose angiostatic treatment counteracts radiotherapy-induced tumor perfusion and enhances the anti-tumor effect

https://doi.org/10.18632/oncotarget.12814

Esther A. Kleibeuker, Emmanouil Fokas, Philip D. Allen, Veerle Kersemans, Arjan W. Griffioen, John Beech, Jaehong H. Im, Sean C. Smart, Kitty C. Castricum, Jaap van den Berg, Iris A. Schulkens, Sally A. Hill, Adrian L. Harris, Ben J. Slotman, Henk M. Verheul, Ruth J. Muschel,  and Victor L. Thijssen
76613-76627
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SPARC overexpression in primary tumors correlates with disease recurrence and overall survival in patients with triple negative breast cancer

SPARC overexpression in primary tumors correlates with disease recurrence and overall survival in patients with triple negative breast cancer

https://doi.org/10.18632/oncotarget.10532

Anjie Zhu, Peng Yuan, Feng Du, Ruoxi Hong, Xiaoyan Ding, Xiuqing Shi, Ying Fan, Jiayu Wang, Yang Luo, Fei Ma, Pin Zhang, Qing Li,  and Binghe Xu
76628-76634
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Immune activity and biodistribution of polypeptide K237 and folic acid conjugated amphiphilic PEG-PLGA copolymer nanoparticles radiolabeled with 99mTc

Immune activity and biodistribution of polypeptide K237 and folic acid conjugated amphiphilic PEG-PLGA copolymer nanoparticles radiolabeled with 99mTc

https://doi.org/10.18632/oncotarget.12850

Zelai He, Xiangyu Zhang, Jingwen Huang, Yufeng Wu, Xuanzhang Huang, Jie Chen, Junyong Xia, Hao Jiang, Jing Ma,  and Jian Wu
76635-76646
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Association of the miR-17-5p variants with susceptibility to cervical cancer in a Chinese population

Association of the miR-17-5p variants with susceptibility to cervical cancer in a Chinese population

https://doi.org/10.18632/oncotarget.12299

Tianbo Jin, Xiaohong Wu, Hua Yang, Ming Liu, Yongjun He, Xue He, Xugang Shi, Fengjiao Wang, Shuli Du, Yajuan Ma, Shan Bao,  and Dongya Yuan
76647-76655
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The natural compound sulforaphene, as a novel anticancer reagent, targeting PI3K-AKT signaling pathway in lung cancer

The natural compound sulforaphene, as a novel anticancer reagent, targeting PI3K-AKT signaling pathway in lung cancer

https://doi.org/10.18632/oncotarget.12307

Ming Yang, Haiyong Wang, Mo Zhou, Weilin Liu, Pengqun Kuang, Hao Liang,  and Qipeng Yuan
76656-76666
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MicroRNA-22 negatively regulates poly(I:C)-triggered type I interferon and inflammatory cytokine production via targeting mitochondrial antiviral signaling protein (MAVS)

MicroRNA-22 negatively regulates poly(I:C)-triggered type I interferon and inflammatory cytokine production via targeting mitochondrial antiviral signaling protein (MAVS)

https://doi.org/10.18632/oncotarget.12395

Shengfeng Wan, Usama Ashraf, Jing Ye, Xiaodong Duan, Ali Zohaib, Wentao Wang, Zheng Chen, Bibo Zhu, Yunchuan Li, Huanchun Chen,  and Shengbo Cao
76667-76683
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Abnormal amphiregulin expression correlates with gastric cancer prognosis

Abnormal amphiregulin expression correlates with gastric cancer prognosis

https://doi.org/10.18632/oncotarget.12436

Bing Wang, Hongmei Yong, Huijun Zhu, Daguang Ni, Sijie Tang, Shu Zhang, Wei Wang, Yan Zhou, Wei Zhao, Guipeng Ding, Jin Zhu, Xiaohua Li,  and Zhenqing Feng
76684-76692
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Human epidermal growth factor receptor 4 (HER4) is a favorable prognostic marker of breast cancer: a systematic review and meta-analysis

Human epidermal growth factor receptor 4 (HER4) is a favorable prognostic marker of breast cancer: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.12485

Jue Wang, Jun Yin, Qing Yang, Feng Ding, Xiao Chen, Bingjie Li,  and Xingsong Tian
76693-76703
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Impact of HPV infection on oral squamous cell carcinoma

Impact of HPV infection on oral squamous cell carcinoma

https://doi.org/10.18632/oncotarget.12501

Carolin Götz, Enken Drecoll, Melanie Straub, Oliver Bissinger, Klaus-Dietrich Wolff,  and Andreas Kolk
76704-76712
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Up-regulation of ribosome biogenesis by MIR196A2 genetic variation promotes endometriosis development and progression

Up-regulation of ribosome biogenesis by MIR196A2 genetic variation promotes endometriosis development and progression

https://doi.org/10.18632/oncotarget.11536

Cherry Yin-Yi Chang, Ming-Tsung Lai, Yi Chen, Ching-Wen Yang, Hui-Wen Chang, Cheng-Chan Lu, Chih-Mei Chen, Carmen Chan, Ching Chung, Chun-Cheng Tseng, Tritium Hwang, Jim Jinn-Chyuan Sheu,  and Fuu-Jen Tsai
76713-76725
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The first investigation of Wilms’ tumour atomic structure-nitrogen and carbon isotopic composition as a novel biomarker for the most individual approach in cancer disease

The first investigation of Wilms’ tumour atomic structure-nitrogen and carbon isotopic composition as a novel biomarker for the most individual approach in cancer disease

https://doi.org/10.18632/oncotarget.12521

Katarzyna Taran, Tomasz Frączek, Anita Sikora-Szubert, Anna Sitkiewicz, Wojciech Młynarski, Józef Kobos,  and Piotr Paneth
76726-76734
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Human cytomegalovirus infection and colorectal cancer risk: a meta-analysis

Human cytomegalovirus infection and colorectal cancer risk: a meta-analysis

https://doi.org/10.18632/oncotarget.12523

Bingjun Bai, Xingxing Wang, Engeng Chen,  and Hongbo Zhu
76735-76742
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The proprotein convertase furin is required to maintain viability of alveolar rhabdomyosarcoma cells

The proprotein convertase furin is required to maintain viability of alveolar rhabdomyosarcoma cells

https://doi.org/10.18632/oncotarget.11648

Patricia Jaaks, Gianmarco Meier, Nagjie Alijaj, Eva Brack, Peter Bode, Ewa Koscielniak, Marco Wachtel, Beat W. Schäfer,  and Michele Bernasconi
76743-76755
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The ETS factor ESE3/EHF represses IL-6 preventing STAT3 activation and expansion of the prostate cancer stem-like compartment

The ETS factor ESE3/EHF represses IL-6 preventing STAT3 activation and expansion of the prostate cancer stem-like compartment

https://doi.org/10.18632/oncotarget.12525

Domenico Albino, Gianluca Civenni, Simona Rossi, Abhishek Mitra, Carlo V. Catapano,  and Giuseppina M. Carbone
76756-76768
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic significance of neutrophil-lymphocyteratio/platelet-lymphocyteratioin lung cancers: a meta-analysis

Prognostic significance of neutrophil-lymphocyteratio/platelet-lymphocyteratioin lung cancers: a meta-analysis

https://doi.org/10.18632/oncotarget.12526

Hong-Bo Yang, Meng Xing, Lei-Na Ma, Ling-Xin Feng,  and Zhuang Yu
76769-76778
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IKKα regulates the stratification and differentiation of the epidermis: implications for skin cancer development

IKKα regulates the stratification and differentiation of the epidermis: implications for skin cancer development

https://doi.org/10.18632/oncotarget.12527

Josefa P. Alameda, Manuel Navarro, Ángel Ramírez, Angustias Page, Cristian Suárez-Cabrera, Rodolfo Moreno-Maldonado, Jesús M. Paramio, María del Carmen Fariña, Marcela Del Río, María Jesús Fernández-Aceñero, Ana Bravo,  and María de los Llanos Casanova
76779-76792
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tofacitinib induces G1 cell-cycle arrest and inhibits tumor growth in Epstein-Barr virus-associated T and natural killer cell lymphoma cells

Tofacitinib induces G1 cell-cycle arrest and inhibits tumor growth in Epstein-Barr virus-associated T and natural killer cell lymphoma cells

https://doi.org/10.18632/oncotarget.12529

Shotaro Ando, Jun-ichi Kawada, Takahiro Watanabe, Michio Suzuki, Yoshitaka Sato, Yuka Torii, Masato Asai, Fumi Goshima, Takayuki Murata, Norio Shimizu, Yoshinori Ito,  and Hiroshi Kimura
76793-76805
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Properdistatin inhibits angiogenesis and improves vascular function in human melanoma xenografts with low thrombospondin-1 expression

Properdistatin inhibits angiogenesis and improves vascular function in human melanoma xenografts with low thrombospondin-1 expression

https://doi.org/10.18632/oncotarget.12695

Jon-Vidar Gaustad, Trude G. Simonsen, Lise Mari K. Andersen,  and Einar K. Rofstad
76806-76815
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Integrative genomics reveals hypoxia inducible genes that are associated with a poor prognosis in neuroblastoma patients

Integrative genomics reveals hypoxia inducible genes that are associated with a poor prognosis in neuroblastoma patients

https://doi.org/10.18632/oncotarget.12713

Mark A. Applebaum, Aashish R. Jha, Clara Kao, Kyle M. Hernandez, Gillian DeWane, Helen R. Salwen, Alexandre Chlenski, Marija Dobratic, Christopher J. Mariani, Lucy A. Godley, Nanduri Prabhakar, Kevin White, Barbara E. Stranger,  and Susan L. Cohn
76816-76826
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activation of endoplasmic reticulum stress promotes autophagy and apoptosis and reverses chemoresistance of human small cell lung cancer cells by inhibiting the PI3K/AKT/mTOR signaling pathway

Activation of endoplasmic reticulum stress promotes autophagy and apoptosis and reverses chemoresistance of human small cell lung cancer cells by inhibiting the PI3K/AKT/mTOR signaling pathway

https://doi.org/10.18632/oncotarget.12718

Xin-Shuang Yu, Juan Du, Yu-Jun Fan, Feng-Jun Liu, Li-Li Cao, Ning Liang, De-Guo Xu,  and Jian-Dong Zhang
76827-76839
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Clinicopathological characteristics and long-term prognosis of screening detected non-palpable breast cancer by ultrasound in hospital-based Chinese population (2001-2014)

Clinicopathological characteristics and long-term prognosis of screening detected non-palpable breast cancer by ultrasound in hospital-based Chinese population (2001-2014)

https://doi.org/10.18632/oncotarget.12319

Bo Pan, Ru Yao, Qing-Li Zhu, Chang-Jun Wang, Shan-Shan You, Jing Zhang, Qian-Qian Xu, Feng Cai, Jie Shi, Yi-Dong Zhou, Feng Mao, Yan Lin, Jing-Hong Guan, Song-Jie Shen, Zhi-Yong Liang, Yu-Xin Jiang,  and Qiang Sun
76840-76851
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Epigenetic silencing of miR-137 contributes to early colorectal carcinogenesis by impaired Aurora-A inhibition

Epigenetic silencing of miR-137 contributes to early colorectal carcinogenesis by impaired Aurora-A inhibition

https://doi.org/10.18632/oncotarget.12719

Yu-Chuan Huang, Chung-Ta Lee, Jenq-Chang Lee, Yao-Wen Liu, Ying-Jen Chen, Joseph T. Tseng, Jui-Wen Kang, Bor-Shyang Sheu, Bo-Wen Lin,  and Liang-Yi Hung
76852-76866
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gene-environment interaction for polymorphisms in ataxia telangiectasia-mutated gene and radiation exposure in carcinogenesis: results from two literature-based meta-analyses of 27120 participants

Gene-environment interaction for polymorphisms in ataxia telangiectasia-mutated gene and radiation exposure in carcinogenesis: results from two literature-based meta-analyses of 27120 participants

https://doi.org/10.18632/oncotarget.12724

Yuguang Zhao, Lei Yang, Di Wu, Hua He, Mengmeng Wang, Tingwen Ge, Yudi Liu, Huimin Tian, Jiuwei Cui, Lin Jia, Ziqiang Wan,  and Fujun Han
76867-76881
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A small deletion in SERPINC1 causes type I antithrombin deficiency by promoting endoplasmic reticulum stress

A small deletion in SERPINC1 causes type I antithrombin deficiency by promoting endoplasmic reticulum stress

https://doi.org/10.18632/oncotarget.12349

Jingjing Su, Liang Shu, Zhou Zhang, Lei Cai, Xin Zhang, Yu Zhai,  and Jianren Liu
76882-76890
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Correlation between anti-PD-L1 tumor concentrations and tumor-specific and nonspecific biomarkers in a melanoma mouse model

Correlation between anti-PD-L1 tumor concentrations and tumor-specific and nonspecific biomarkers in a melanoma mouse model

https://doi.org/10.18632/oncotarget.12727

Ana M. Contreras-Sandoval, María Merino, Marcos Vasquez, Iñaki F. Trocóniz, Pedro Berraondo,  and María J. Garrido
76891-76901
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T-cell responses against CD19+ pediatric acute lymphoblastic leukemia mediated by bispecific T-cell engager (BiTE) are regulated contrarily by PD-L1 and CD80/CD86 on leukemic blasts

T-cell responses against CD19+ pediatric acute lymphoblastic leukemia mediated by bispecific T-cell engager (BiTE) are regulated contrarily by PD-L1 and CD80/CD86 on leukemic blasts

https://doi.org/10.18632/oncotarget.12357

Judith Feucht, Simone Kayser, David Gorodezki, Mohamad Hamieh, Michaela Döring, Franziska Blaeschke, Patrick Schlegel, Hans Bösmüller, Leticia Quintanilla-Fend, Martin Ebinger, Peter Lang, Rupert Handgretinger,  and Tobias Feuchtinger
76902-76919
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Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer

Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer

https://doi.org/10.18632/oncotarget.12729

Astrid Escudero-Esparza, Michael Bartoschek, Chrysostomi Gialeli, Marcin Okroj, Sioned Owen, Karin Jirström, Akira Orimo, Wen G. Jiang, Kristian Pietras,  and Anna M. Blom
76920-76933
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic significance of serum beta-2 microglobulin in patients with diffuse large B-cell lymphoma in the rituximab era

Prognostic significance of serum beta-2 microglobulin in patients with diffuse large B-cell lymphoma in the rituximab era

https://doi.org/10.18632/oncotarget.12734

Seyoung Seo, Jung Yong Hong, Shinkyo Yoon, Changhoon Yoo, Ji Hyun Park, Jung Bok Lee, Chan-sik Park, Jooryung Huh, Yoonse Lee, Kyung Won Kim, Jin-Sook Ryu, Seok Jin Kim, Won Seog Kim, Dok Hyun Yoon,  and Cheolwon Suh
76934-76943
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevation of n-3/n-6 PUFAs ratio suppresses mTORC1 and prevents colorectal carcinogenesis associated with APC mutation

Elevation of n-3/n-6 PUFAs ratio suppresses mTORC1 and prevents colorectal carcinogenesis associated with APC mutation

https://doi.org/10.18632/oncotarget.12759

Miao Liu, Ling Zhou, Baiyu Zhang, Minhong He, Xiaoying Dong, Xiaojun Lin, Chunhong Jia, Xiaochun Bai, Yifan Dai, Yongchun Su, Zhipeng Zou,  and Hang Zheng
76944-76954
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CFTR is a potential marker for nasopharyngeal carcinoma prognosis and metastasis

CFTR is a potential marker for nasopharyngeal carcinoma prognosis and metastasis

https://doi.org/10.18632/oncotarget.12762

Ziwei Tu, Qu Chen, Jie Ting Zhang, Xiaohua Jiang, Yunfei Xia,  and Hsiao Chang Chan
76955-76965
Abstract  |  PDF  |  HTML  |  Order a Reprint

An in vitro 3D bone metastasis model by using a human bone tissue culture and human sex-related cancer cells

An in vitro 3D bone metastasis model by using a human bone tissue culture and human sex-related cancer cells

https://doi.org/10.18632/oncotarget.12763

Francesca Salamanna, Veronica Borsari, Silvia Brogini, Gianluca Giavaresi, Annapaola Parrilli, Simona Cepollaro, Matteo Cadossi, Lucia Martini, Antonio Mazzotti,  and Milena Fini
76966-76983
Abstract  |  PDF  |  HTML  |  Order a Reprint

Phosphorylation of PPARγ at Ser84 promotes glycolysis and cell proliferation in hepatocellular carcinoma by targeting PFKFB4

Phosphorylation of PPARγ at Ser84 promotes glycolysis and cell proliferation in hepatocellular carcinoma by targeting PFKFB4

https://doi.org/10.18632/oncotarget.12764

Yuxin Shu, Yan Lu, Xiaojuan Pang, Wei Zheng, Yahong Huang, Jiahong Li, Jianguo Ji, Can Zhang,  and Pingping Shen
76984-76994
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: the role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathways

Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: the role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathways

https://doi.org/10.18632/oncotarget.12765

Wohn-Jenn Leu, Sharada Prasanna Swain, She-Hung Chan, Jui-Ling Hsu, Shih-Ping Liu, Mei-Ling Chan, Chia-Chun Yu, Lih-Ching Hsu, Yen-Lin Chou, Wei-Ling Chang, Duen-Ren Hou,  and Jih-Hwa Guh
76995-77009
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PD-L1 expression in tonsillar cancer is associated with human papillomavirus positivity and improved survival: implications for anti-PD1 clinical trials

PD-L1 expression in tonsillar cancer is associated with human papillomavirus positivity and improved survival: implications for anti-PD1 clinical trials

https://doi.org/10.18632/oncotarget.12776

Angela M Hong, Ricardo E Vilain, Sarah Romanes, Jean Yang, Elizabeth Smith, Deanna Jones, Richard A Scolyer, C Soon Lee, Mei Zhang,  and Barbara Rose
77010-77020
Abstract  |  PDF  |  HTML  |  Order a Reprint

Generation of CD20-specific TCRs for TCR gene therapy of CD20low B-cell malignancies insusceptible to CD20-targeting antibodies

Generation of CD20-specific TCRs for TCR gene therapy of CD20low B-cell malignancies insusceptible to CD20-targeting antibodies

https://doi.org/10.18632/oncotarget.12778

Lorenz Jahn, Dirk M. van der Steen, Renate S. Hagedoorn, Pleun Hombrink, Michel G.D. Kester, Marjolein P. Schoonakker, Daniëlle de Ridder, Peter A. van Veelen, J.H. Frederik Falkenburg,  and Mirjam H.M. Heemskerk
77021-77037
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Efficacy of glycogen synthase kinase-3β targeting against osteosarcoma via activation of β-catenin

Efficacy of glycogen synthase kinase-3β targeting against osteosarcoma via activation of β-catenin

https://doi.org/10.18632/oncotarget.12781

Shingo Shimozaki, Norio Yamamoto, Takahiro Domoto, Hideji Nishida, Katsuhiro Hayashi, Hiroaki Kimura, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Takashi Kato, Yu Aoki, Takashi Higuchi, Mayumi Hirose, Robert M Hoffman, Toshinari Minamoto,  and Hiroyuki Tsuchiya
77038-77051
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reduced expression of FILIP1L, a novel WNT pathway inhibitor, is associated with poor survival, progression and chemoresistance in ovarian cancer

Reduced expression of FILIP1L, a novel WNT pathway inhibitor, is associated with poor survival, progression and chemoresistance in ovarian cancer

https://doi.org/10.18632/oncotarget.12784

Mijung Kwon, Jae-Hoon Kim, Yevangelina Rybak, Alex Luna, Chel Hun Choi, Joon-Yong Chung, Stephen M. Hewitt, Asha Adem, Elizabeth Tubridy, Juan Lin,  and Steven K. Libutti
77052-77070
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Estrogen related receptor alpha in castration-resistant prostate cancer cells promotes tumor progression in bone

Estrogen related receptor alpha in castration-resistant prostate cancer cells promotes tumor progression in bone

https://doi.org/10.18632/oncotarget.12787

Anais Fradet, Mathilde Bouchet, Carine Delliaux, Manon Gervais, Casina Kan, Claire Benetollo, Francesco Pantano, Geoffrey Vargas, Lamia Bouazza, Martine Croset, Yohann Bala, Xavier Leroy, Thomas J Rosol, Jennifer Rieusset, Akeila Bellahcène, Vincent Castronovo, Jane E Aubin, Philippe Clézardin, Martine Duterque-Coquillaud,  and Edith Bonnelye
77071-77086
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Differential role of intravenous anesthetics in colorectal cancer progression: implications for clinical application

Differential role of intravenous anesthetics in colorectal cancer progression: implications for clinical application

https://doi.org/10.18632/oncotarget.12800

Fengliu Deng, Mingwen Ouyang, Xiaofei Wang, Xueqing Yao, Yeming Chen, Tao Tao, Xuegang Sun, Lijun Xu, Jing Tang,  and Liang Zhao
77087-77095
Abstract  |  PDF  |  HTML  |  Order a Reprint

CDDO-Me reveals USP7 as a novel target in ovarian cancer cells

CDDO-Me reveals USP7 as a novel target in ovarian cancer cells

https://doi.org/10.18632/oncotarget.12801

Dongjun Qin, Weiwei Wang, Hu Lei, Hao Luo, Haiyan Cai, Caixia Tang, Yunzhao Wu, Yingying Wang, Jin Jin, Weilie Xiao, Tongdan Wang, Chunmin Ma, Hanzhang Xu, Jinfu Zhang, Fenghou Gao,  and Ying-Li Wu
77096-77109
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Meta-analysis of the correlation between selenium and incidence of hepatocellular carcinoma

Meta-analysis of the correlation between selenium and incidence of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.12804

Ziwei Zhang, Mingyu Bi, Qi Liu, Jie Yang,  and Shiwen Xu
77110-77116
Abstract  |  PDF  |  HTML  |  Order a Reprint

Angiotensin II receptor 1 gene variants are associated with high-altitude pulmonary edema risk

Angiotensin II receptor 1 gene variants are associated with high-altitude pulmonary edema risk

https://doi.org/10.18632/oncotarget.12489

Tianbo Jin, Yongchao Ren, Xikai Zhu, Xun Li, Yongri Ouyang, Na He, Zhiying Zhang, Yuan Zhang, Longli Kang,  and Dongya Yuan
77117-77123
Abstract  |  PDF  |  HTML  |  Order a Reprint

TGF-β signal rewiring sustains epithelial-mesenchymal transition of circulating tumor cells in prostate cancer xenograft hosts

TGF-β signal rewiring sustains epithelial-mesenchymal transition of circulating tumor cells in prostate cancer xenograft hosts

https://doi.org/10.18632/oncotarget.12808

Guangcun Huang, Pawel A. Osmulski, Hakim Bouamar, Devalingam Mahalingam, Chun-Lin Lin, Michael A. Liss, Addanki Pratap Kumar, Chun-Liang Chen, Ian M. Thompson, Lu-Zhe Sun, Maria E. Gaczynska,  and Tim H.-M. Huang
77124-77137
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IL27 controls skin tumorigenesis via accumulation of ETAR-positive CD11b cells in the pre-malignant skin

IL27 controls skin tumorigenesis via accumulation of ETAR-positive CD11b cells in the pre-malignant skin

https://doi.org/10.18632/oncotarget.12581

Denada Dibra, Abhisek Mitra, Melissa Newman, Xueqing Xia, Camille Keenan, Jeffry J. Cutrera, J. Michael Mathis, Xiao-Jing Wang, Jeffrey Myers,  and Shulin Li
77138-77151
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Marital status is an independent prognostic factor for tracheal cancer patients: an analysis of the SEER database

Marital status is an independent prognostic factor for tracheal cancer patients: an analysis of the SEER database

https://doi.org/10.18632/oncotarget.12809

Mu Li, Chen-Yang Dai, Yu-Ning Wang, Tao Chen, Long Wang, Ping Yang, Dong Xie, Rui Mao,  and Chang Chen
77152-77162
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Co-existence of BRAF and NRAS driver mutations in the same melanoma cells results in heterogeneity of targeted therapy resistance

Co-existence of BRAF and NRAS driver mutations in the same melanoma cells results in heterogeneity of targeted therapy resistance

https://doi.org/10.18632/oncotarget.12848

Marieke I.G. Raaijmakers, Daniel S. Widmer, Apurva Narechania, Ossia Eichhoff, Sandra N. Freiberger, Judith Wenzina, Phil F. Cheng, Daniela Mihic-Probst, Rob Desalle, Reinhard Dummer,  and Mitchell P. Levesque
77163-77174
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association of transcription factor 7-like 2 gene polymorphisms with breast cancer risk in northwest Chinese women

Association of transcription factor 7-like 2 gene polymorphisms with breast cancer risk in northwest Chinese women

https://doi.org/10.18632/oncotarget.12591

Weili Min, Xinghan Liu, Ye Lu, Zhuoqing Gong, Meng Wang, Shuai Lin, Huafeng Kang, Tianbo Jin, Xijing Wang, Xiaobin Ma, Kang Liu, Cong Dai, Yi Zheng, Shanli Li, Qingyong Ma,  and Zhijun Dai
77175-77182
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Blocking hepatic metastases of colon cancer cells using an shRNA against Rac1 delivered by activatable cell-penetrating peptide

Blocking hepatic metastases of colon cancer cells using an shRNA against Rac1 delivered by activatable cell-penetrating peptide

https://doi.org/10.18632/oncotarget.12854

Ying Bao, Huihui Guo, Yongliang Lu, Wenming Feng, Xinrong Sun, Chengwu Tang, Xiang Wang,  and Mo Shen
77183-77195
Abstract  |  PDF  |  HTML  |  Order a Reprint

E-cigarettes and flavorings induce inflammatory and pro-senescence responses in oral epithelial cells and periodontal fibroblasts

E-cigarettes and flavorings induce inflammatory and pro-senescence responses in oral epithelial cells and periodontal fibroblasts

https://doi.org/10.18632/oncotarget.12857

Isaac K. Sundar, Fawad Javed, Georgios E. Romanos,  and Irfan Rahman
77196-77204
Abstract  |  PDF  |  HTML  |  Interview with Dr. Irfan Rahman  |  Order a Reprint

Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents

Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents

https://doi.org/10.18632/oncotarget.12858

Julie Gaston, Laura Cheradame, Vanessa Yvonnet, Olivier Deas, Marie-France Poupon, Jean-Gabriel Judde, Stefano Cairo,  and Vincent Goffin
77205-77224
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LncRNA profile study reveals four-lncRNA signature associated with the prognosis of patients with anaplastic gliomas

LncRNA profile study reveals four-lncRNA signature associated with the prognosis of patients with anaplastic gliomas

https://doi.org/10.18632/oncotarget.12624

Wen Wang, Fan Yang, Lu Zhang, Jing Chen, Zheng Zhao, Haoyuan Wang, Fan Wu, Tingyu Liang, Xiaoyan Yan, Jiye Li, Qing Lan, Jiangfei Wang,  and Jizong Zhao
77225-77236
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Assessment of combined expression of B7-H3 and B7-H4 as prognostic marker in esophageal cancer patients

Assessment of combined expression of B7-H3 and B7-H4 as prognostic marker in esophageal cancer patients

https://doi.org/10.18632/oncotarget.12628

Lujun Chen, Quanqin Xie, Zhigang Wang, Liangrong Shi, Changping Wu,  and Jingting Jiang
77237-77243
Abstract  |  PDF  |  HTML  |  Order a Reprint

Elevated AEG-1 expression in macrophages promotes hypopharyngeal cancer invasion through the STAT3-MMP-9 signaling pathway

Elevated AEG-1 expression in macrophages promotes hypopharyngeal cancer invasion through the STAT3-MMP-9 signaling pathway

https://doi.org/10.18632/oncotarget.12886

Xiuxiu Liu, Zhenghua Lv, Jidong Zou, Xianfang Liu, Juke Ma, Chengtao Sun, Na Sa,  and Wei Xu
77244-77256
Abstract  |  PDF  |  HTML  |  Order a Reprint

PDGFR-alpha inhibits melanoma growth via CXCL10/IP-10: a multi-omics approach

PDGFR-alpha inhibits melanoma growth via CXCL10/IP-10: a multi-omics approach

https://doi.org/10.18632/oncotarget.12629

Daniela D’Arcangelo, Francesco Facchiano, Giovanni Nassa, Andrea Stancato, Annalisa Antonini, Stefania Rossi, Cinzia Senatore, Martina Cordella, Claudio Tabolacci, Annamaria Salvati, Roberta Tarallo, Alessandro Weisz, Angelo M. Facchiano,  and Antonio Facchiano
77257-77275
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Proximal and distal regulation of the HYAL1 gene cluster by the estrogen receptor α in breast cancer cells

Proximal and distal regulation of the HYAL1 gene cluster by the estrogen receptor α in breast cancer cells

https://doi.org/10.18632/oncotarget.12630

Lydia Edjekouane, Samira Benhadjeba, Maïka Jangal, Hubert Fleury, Nicolas Gévry, Euridice Carmona,  and André Tremblay
77276-77290
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

AXL modulates extracellular matrix protein expression and is essential for invasion and metastasis in endometrial cancer

AXL modulates extracellular matrix protein expression and is essential for invasion and metastasis in endometrial cancer

https://doi.org/10.18632/oncotarget.12637

Laura M. Divine, Mai R. Nguyen, Eric Meller, Riva A. Desai, Batool Arif, Erinn B. Rankin, Katherine H. Bligard, Cherise Meyerson, Ian S. Hagemann, Maria Massad, Premal H. Thaker, Andrea R. Hagemann, Carolyn K. McCourt, Matt A. Powell, David G. Mutch,  and Katherine C. Fuh
77291-77305
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

DcR3 induces epithelial-mesenchymal transition through activation of the TGF-β3/SMAD signaling pathway in CRC

DcR3 induces epithelial-mesenchymal transition through activation of the TGF-β3/SMAD signaling pathway in CRC

https://doi.org/10.18632/oncotarget.12639

Yan-Ping Liu, Hui-Fang Zhu, Ding-li Liu, Zhi-Yan Hu, Sheng-Nan Li, He-Ping Kan, Xiao-Yan Wang,  and Zu-Guo Li
77306-77318
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Risk of lung cancer in Parkinson’s disease

Risk of lung cancer in Parkinson’s disease

https://doi.org/10.18632/oncotarget.12964

Xin Xie, Xiaoguang Luo, Mingliang Xie, Yang Liu,  and Ting Wu
77319-77325
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel 3D mesenchymal stem cell model of the multiple myeloma bone marrow niche: biologic and clinical applications

A novel 3D mesenchymal stem cell model of the multiple myeloma bone marrow niche: biologic and clinical applications

https://doi.org/10.18632/oncotarget.12643

Jana Jakubikova, Danka Cholujova, Teru Hideshima, Paulina Gronesova, Andrea Soltysova, Takeshi Harada, Jungnam Joo, Sun-Young Kong, Raphael E. Szalat, Paul G. Richardson, Nikhil C. Munshi, David M. Dorfman,  and Kenneth C. Anderson
77326-77341
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression of OCT4 is associated with gefitinib resistance in non-small cell lung cancer

Overexpression of OCT4 is associated with gefitinib resistance in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.12999

Bin Li, Zhouhong Yao, Yunyan Wan,  and Dianjie Lin
77342-77347
Abstract  |  PDF  |  HTML  |  Order a Reprint

Polymeric nanoparticle-docetaxel for the treatment of advanced solid tumors: phase I clinical trial and preclinical data from an orthotopic pancreatic cancer model

Polymeric nanoparticle-docetaxel for the treatment of advanced solid tumors: phase I clinical trial and preclinical data from an orthotopic pancreatic cancer model

https://doi.org/10.18632/oncotarget.12668

Si Yeol Song, Kyu-pyo Kim, Seong-Yun Jeong, Jin Park, Jaesook Park, Joohee Jung, Hye Kyung Chung, Sa-Won Lee, Min Hyo Seo, Jung-shin Lee, Kyung Hae Jung,  and Eun Kyung Choi
77348-77357
Abstract  |  PDF  |  HTML  |  Order a Reprint

GWAS in the SIGNAL/PHARE clinical cohort restricts the association between the FGFR2 locus and estrogen receptor status to HER2-negative breast cancer patients

GWAS in the SIGNAL/PHARE clinical cohort restricts the association between the FGFR2 locus and estrogen receptor status to HER2-negative breast cancer patients

https://doi.org/10.18632/oncotarget.12669

David G. Cox, Elsa Curtit, Gilles Romieu, Pierre Fumoleau, Maria Rios, Hervé Bonnefoi, Thomas Bachelot, Patrick Soulié, Christelle Jouannaud, Hugues Bourgeois, Thierry Petit, Isabelle Tennevet, David Assouline, Marie-Christine Mathieu, Jean-Philippe Jacquin, Sandrine Lavau-Denes, Ariane Darut-Jouve, Jean-Marc Ferrero, Carole Tarpin, Christelle Lévy, Valérie Delecroix, Véronique Trillet-Lenoir, Oana Cojocarasu, Jérôme Meunier, Jean-Yves Pierga, Céline Faure-Mercier, Hélène Blanché, Mourad Sahbatou, Anne Boland, Delphine Bacq, Céline Besse, Jean-François Deleuze, Iris Pauporté, Gilles Thomas,  and Xavier Pivot
77358-77364
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FOXM1 and STAT3 interaction confers radioresistance in glioblastoma cells

FOXM1 and STAT3 interaction confers radioresistance in glioblastoma cells

https://doi.org/10.18632/oncotarget.12670

Uday B. Maachani, Uma Shankavaram, Tamalee Kramp, Philip J. Tofilon, Kevin Camphausen,  and Anita T. Tandle
77365-77377
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MYCL is a target of a BET bromodomain inhibitor, JQ1, on growth suppression efficacy in small cell lung cancer cells

MYCL is a target of a BET bromodomain inhibitor, JQ1, on growth suppression efficacy in small cell lung cancer cells

https://doi.org/10.18632/oncotarget.12671

Fuyumi Kato, Francesco Paolo Fiorentino, Andreu Alibés, Manuel Perucho, Montse Sánchez-Céspedes, Takashi Kohno,  and Jun Yokota
77378-77388
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CD133+CD54+CD44+ circulating tumor cells as a biomarker of treatment selection and liver metastasis in patients with colorectal cancer

CD133+CD54+CD44+ circulating tumor cells as a biomarker of treatment selection and liver metastasis in patients with colorectal cancer

https://doi.org/10.18632/oncotarget.12675

Chao Fang, Chuanwen Fan, Cun Wang, Qiaorong Huang, Wentong Meng, Yongyang Yu, Lie Yang, Zhihai Peng, Jiankun Hu, Yuan Li, Xianming Mo,  and Zongguang Zhou
77389-77403
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nivolumab for advanced melanoma: pretreatment prognostic factors and early outcome markers during therapy

Nivolumab for advanced melanoma: pretreatment prognostic factors and early outcome markers during therapy

https://doi.org/10.18632/oncotarget.12677

Yoshio Nakamura, Shigehisa Kitano, Akira Takahashi, Arata Tsutsumida, Kenjiro Namikawa, Keiji Tanese, Takayuki Abe, Takeru Funakoshi, Noboru Yamamoto, Masayuki Amagai,  and Naoya Yamazaki
77404-77415
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Resistance to neoplastic transformation of ex-vivo expanded human mesenchymal stromal cells after exposure to supramaximal physical and chemical stress

Resistance to neoplastic transformation of ex-vivo expanded human mesenchymal stromal cells after exposure to supramaximal physical and chemical stress

https://doi.org/10.18632/oncotarget.12678

Antonella Conforti, Nadia Starc, Simone Biagini, Luigi Tomao, Angela Pitisci, Mattia Algeri, Pietro Sirleto, Antonio Novelli, Giulia Grisendi, Olivia Candini, Cintia Carella, Massimo Dominici, Franco Locatelli,  and Maria Ester Bernardo
77416-77429
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

c-Myc suppresses miR-451⊣YWTAZ/AKT axis via recruiting HDAC3 in acute myeloid leukemia

c-Myc suppresses miR-451⊣YWTAZ/AKT axis via recruiting HDAC3 in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.12679

Rui Su, Jia-Nan Gong, Ming-Tai Chen, Li Song, Chao Shen, Xin-Hua Zhang, Xiao-Lin Yin, Hong-Mei Ning, Bing Liu, Fang Wang, Yan-Ni Ma, Hua-Lu Zhao, Jia Yu,  and Jun-Wu Zhang
77430-77443
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The feedback loop of LITAF and BCL6 is involved in regulating apoptosis in B cell non-Hodgkin’s-lymphoma

The feedback loop of LITAF and BCL6 is involved in regulating apoptosis in B cell non-Hodgkin’s-lymphoma

https://doi.org/10.18632/oncotarget.12680

Yaoyao Shi, Yue Kuai, Lizhen Lei, Yuanyuan Weng, Friederike Berberich-Siebelt, Xinxia Zhang, Jinjie Wang, Yuan Zhou, Xin Jiang, Guoping Ren, Hongyang Pan, Zhengrong Mao,  and Ren Zhou
77444-77456
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mitochondrial Lon is over-expressed in high-grade gliomas, and mediates hypoxic adaptation: potential role of Lon as a therapeutic target in glioma

Mitochondrial Lon is over-expressed in high-grade gliomas, and mediates hypoxic adaptation: potential role of Lon as a therapeutic target in glioma

https://doi.org/10.18632/oncotarget.12681

Kaijun Di, Naomi Lomeli, Spencer D. Wood, Christopher D. Vanderwal,  and Daniela A. Bota
77457-77467
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-7 inhibits cell proliferation, migration and invasion in human non-small cell lung cancer cells by targeting FAK through ERK/MAPK signaling pathway

MicroRNA-7 inhibits cell proliferation, migration and invasion in human non-small cell lung cancer cells by targeting FAK through ERK/MAPK signaling pathway

https://doi.org/10.18632/oncotarget.12684

Qi Cao, Zheng-Dao Mao, Yu-Jia Shi, Yi Chen, Yun Sun, Qian Zhang, Lei Song,  and Li-Ping Peng
77468-77481
Abstract  |  PDF  |  HTML  |  Order a Reprint

Serum APE1 as a predictive marker for platinum-based chemotherapy of non-small cell lung cancer patients

Serum APE1 as a predictive marker for platinum-based chemotherapy of non-small cell lung cancer patients

https://doi.org/10.18632/oncotarget.13030

Shiheng Zhang, Le He, Nan Dai, Wei Guan, Jinlu Shan, Xueqin Yang, Zhaoyang Zhong, Yi Qing, Feng Jin, Chuan Chen, Yuxin Yang, Hongyi Wang, Laura Baugh, Gianluca Tell, David M. Wilson III, Mengxia Li,  and Dong Wang
77482-77494
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FAM83D associates with high tumor recurrence after liver transplantation involving expansion of CD44+ carcinoma stem cells

FAM83D associates with high tumor recurrence after liver transplantation involving expansion of CD44+ carcinoma stem cells

https://doi.org/10.18632/oncotarget.12715

Binyi Lin, Tianchi Chen, Qijun Zhang, Xiaoxiao Lu, Zhiyun Zheng, Jun Ding, Jinfeng Liu, Zhe Yang, Lei Geng, Liming Wu, Lin Zhou,  and Shusen Zheng
77495-77507
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-424 acts as a tumor radiosensitizer by targeting aprataxin in cervical cancer

miR-424 acts as a tumor radiosensitizer by targeting aprataxin in cervical cancer

https://doi.org/10.18632/oncotarget.12716

Xia Wang, Qing Li, Hua Jin, Hua Zou, Wei Xia, Nan Dai, Xiao-Yan Dai, Dong Wang, Cheng-Xiong Xu,  and Yi Qing
77508-77515
Abstract  |  PDF  |  HTML  |  Order a Reprint

Protein phosphatase Mg2+/Mn2+ dependent 1F promotes smoking-induced breast cancer by inactivating phosphorylated-p53-induced signals

Protein phosphatase Mg2+/Mn2+ dependent 1F promotes smoking-induced breast cancer by inactivating phosphorylated-p53-induced signals

https://doi.org/10.18632/oncotarget.12717

Shih-Hsin Tu, Yin-Ching Lin, Chi-Cheng Huang, Po-Sheng Yang, Hui-Wen Chang, Chien-Hsi Chang, Chih-Hsiung Wu, Li-Ching Chen,  and Yuan-Soon Ho
77516-77531
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Melatonin promotes goat spermatogonia stem cells (SSCs) proliferation by stimulating glial cell line-derived neurotrophic factor (GDNF) production in Sertoli cells

Melatonin promotes goat spermatogonia stem cells (SSCs) proliferation by stimulating glial cell line-derived neurotrophic factor (GDNF) production in Sertoli cells

https://doi.org/10.18632/oncotarget.12720

Bowen Niu, Bo Li, Chongyang Wu, Jiang Wu, Yuan Yan, Rui Shang, Chunling Bai, Guangpeng Li,  and Jinlian Hua
77532-77542
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cannabinoids synergize with carfilzomib, reducing multiple myeloma cells viability and migration

Cannabinoids synergize with carfilzomib, reducing multiple myeloma cells viability and migration

https://doi.org/10.18632/oncotarget.12721

Massimo Nabissi, Maria Beatrice Morelli, Massimo Offidani, Consuelo Amantini, Silvia Gentili, Alessandra Soriani, Claudio Cardinali, Pietro Leoni,  and Giorgio Santoni
77543-77557
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Peripheral blood lymphocyte subset levels differ in patients with hepatocellular carcinoma

Peripheral blood lymphocyte subset levels differ in patients with hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.13041

Hai-Zhou Liu, Wei Deng, Ji-Lin Li, Ya-Mei Tang, Li-Tu Zhang, Ying Cui,  and Xin-Qiang Liang
77558-77564
Abstract  |  PDF  |  HTML  |  Order a Reprint

Biopsy proportion of tumour predicts pathological tumour response and benefit from chemotherapy in resectable oesophageal carcinoma: results from the UK MRC OE02 trial

Biopsy proportion of tumour predicts pathological tumour response and benefit from chemotherapy in resectable oesophageal carcinoma: results from the UK MRC OE02 trial

https://doi.org/10.18632/oncotarget.12723

Matthew D. Hale, Matthew Nankivell, Gordon G. Hutchins, Sally P. Stenning, Ruth E. Langley, Wolfram Mueller, Nicholas P. West, Alexander I. Wright, Darren Treanor, Lindsay C. Hewitt, William H. Allum, David Cunningham, Jeremy D. Hayden,  and Heike I. Grabsch
77565-77575
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Progesterone potentiates the growth inhibitory effects of calcitriol in endometrial cancer via suppression of CYP24A1

Progesterone potentiates the growth inhibitory effects of calcitriol in endometrial cancer via suppression of CYP24A1

https://doi.org/10.18632/oncotarget.12725

Amber A. Bokhari, Laura R. Lee, Dewayne Raboteau, Jane Turbov, Isabel V. Rodriguez, John Wesley Pike, Chad A. Hamilton, George Larry Maxwell, Gustavo C. Rodriguez,  and Viqar Syed
77576-77590
Abstract  |  PDF  |  HTML  |  Order a Reprint

Nuclear FOXO3 predicts adverse clinical outcome and promotes tumor angiogenesis in neuroblastoma

Nuclear FOXO3 predicts adverse clinical outcome and promotes tumor angiogenesis in neuroblastoma

https://doi.org/10.18632/oncotarget.12728

Judith Hagenbuchner, Martina Rupp, Christina Salvador, Bernhard Meister, Ursula Kiechl-Kohlendorfer, Thomas Müller, Kathrin Geiger, Consolato Sergi, Petra Obexer,  and Michael J. Ausserlechner
77591-77606
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The relationship between total and phosphorylated STAT1 and STAT3 tumour cell expression, components of tumour microenvironment and survival in patients with invasive ductal breast cancer

The relationship between total and phosphorylated STAT1 and STAT3 tumour cell expression, components of tumour microenvironment and survival in patients with invasive ductal breast cancer

https://doi.org/10.18632/oncotarget.12730

Fadia J.A. Gujam, Donald C. McMillan,  and Joanne Edwards
77607-77621
Abstract  |  PDF  |  HTML  |  Order a Reprint

Bortezomib-resistance is associated with increased levels of proteasome subunits and apoptosis-avoidance

Bortezomib-resistance is associated with increased levels of proteasome subunits and apoptosis-avoidance

https://doi.org/10.18632/oncotarget.12731

Yi-Xin Wu, Jia-Hua Yang,  and Hirotomo Saitsu
77622-77634
Abstract  |  PDF  |  HTML  |  Order a Reprint

Bcr-abl regulates Stat5 through Shp2, the interferon consensus sequence binding protein (Icsbp/Irf8), growth arrest specific 2 (Gas2) and calpain

Bcr-abl regulates Stat5 through Shp2, the interferon consensus sequence binding protein (Icsbp/Irf8), growth arrest specific 2 (Gas2) and calpain

https://doi.org/10.18632/oncotarget.12749

Elizabeth E. Hjort, Weiqi Huang, Liping Hu,  and Elizabeth A. Eklund
77635-77650
Abstract  |  PDF  |  HTML  |  Order a Reprint

Risk of eighteen genome-wide association study-identified genetic variants for colorectal cancer and colorectal adenoma in Han Chinese

Risk of eighteen genome-wide association study-identified genetic variants for colorectal cancer and colorectal adenoma in Han Chinese

https://doi.org/10.18632/oncotarget.12750

Chunwen Tan, Wangxiong Hu, Yanqin Huang, Jiaojiao Zhou,  and Shu Zheng
77651-77663
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Suppression of gain-of-function mutant p53 with metabolic inhibitors reduces tumor growth in vivo

Suppression of gain-of-function mutant p53 with metabolic inhibitors reduces tumor growth in vivo

https://doi.org/10.18632/oncotarget.12758

Chae Lim Jung, Hyemin Mun, Se-Young Jo, Ju-Hee Oh, ChuHee Lee, Eun-Kyung Choi, Se Jin Jang,  and Young-Ah Suh
77664-77682
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Integrin α2β1 inhibits MST1 kinase phosphorylation and activates Yes-associated protein oncogenic signaling in hepatocellular carcinoma

Integrin α2β1 inhibits MST1 kinase phosphorylation and activates Yes-associated protein oncogenic signaling in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.12760

Kwong-Fai Wong, Angela M. Liu, Wanjin Hong, Zhi Xu,  and John M. Luk
77683-77695
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Secreted protein acidic and rich in cysteine (SPARC) induces lipotoxicity in neuroblastoma by regulating transport of albumin complexed with fatty acids

Secreted protein acidic and rich in cysteine (SPARC) induces lipotoxicity in neuroblastoma by regulating transport of albumin complexed with fatty acids

https://doi.org/10.18632/oncotarget.12773

Alexandre Chlenski, Marija Dobratic, Helen R. Salwen, Mark Applebaum, Lisa J. Guerrero, Ryan Miller, Gillian DeWane, Elena Solomaha, Jeremy D. Marks,  and Susan L. Cohn
77696-77706
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SIRT1 suppresses adipogenesis by activating Wnt/β-catenin signaling in vivo and in vitro

SIRT1 suppresses adipogenesis by activating Wnt/β-catenin signaling in vivo and in vitro

https://doi.org/10.18632/oncotarget.12774

Yuanfei Zhou, Tongxing Song, Jie Peng, Zheng Zhou, Hongkui Wei, Rui Zhou, Siwen Jiang,  and Jian Peng
77707-77720
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PD-L2 negatively regulates Th1-mediated immunopathology during Fasciola hepatica infection

PD-L2 negatively regulates Th1-mediated immunopathology during Fasciola hepatica infection

https://doi.org/10.18632/oncotarget.12790

Cinthia C. Stempin, Claudia C. Motrán, María P. Aoki, Cristian R. Falcón, Fabio M. Cerbán,  and Laura Cervi
77721-77731
Abstract  |  PDF  |  HTML  |  Order a Reprint

Efficient generation of antigen-specific CTLs by the BAFF-activated human B Lymphocytes as APCs: a novel approach for immunotherapy

Efficient generation of antigen-specific CTLs by the BAFF-activated human B Lymphocytes as APCs: a novel approach for immunotherapy

https://doi.org/10.18632/oncotarget.12792

Zhang Yiwen, Gao Shilin, Chen Yingshi, Su Lishi, Luo Baohong, Liu Chao, Li Linghua, Pan Ting,  and Zhang Hui
77732-77748
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The somite-secreted factor Maeg promotes zebrafish embryonic angiogenesis

The somite-secreted factor Maeg promotes zebrafish embryonic angiogenesis

https://doi.org/10.18632/oncotarget.12793

Xin Wang, Wei Yuan, Xueqian Wang, Jialing Qi, Yinyin Qin, Yunwei Shi, Jie Zhang, Jie Gong, Zhangji Dong, Xiaoyu Liu, Chen Sun, Renjie Chai, Ferdinand Le Noble,  and Dong Liu
77749-77763
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-3196 is inhibited by H2AX phosphorylation and attenuates lung cancer cell apoptosis by downregulating PUMA

MicroRNA-3196 is inhibited by H2AX phosphorylation and attenuates lung cancer cell apoptosis by downregulating PUMA

https://doi.org/10.18632/oncotarget.12794

Chengshan Xu, Ling Zhang, Lianning Duan,  and Chengrong Lu
77764-77776
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MCM10 overexpression implicates adverse prognosis in urothelial carcinoma

MCM10 overexpression implicates adverse prognosis in urothelial carcinoma

https://doi.org/10.18632/oncotarget.12795

Wei-Ming Li, Chun-Nung Huang, Hung-Lung Ke, Ching-Chia Li, Yu-Ching Wei, Hsin-Chih Yeh, Lin-Li Chang, Chun-Hsiung Huang, Peir-In Liang, Bi-Wen Yeh, Ti-Chun Chan, Chien-Feng Li,  and Wen-Jeng Wu
77777-77792
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value of plasma levels of HIF-1a and PGC-1a in breast cancer

Prognostic value of plasma levels of HIF-1a and PGC-1a in breast cancer

https://doi.org/10.18632/oncotarget.12796

Feng-Feng Cai, Cheng Xu, Xin Pan, Lu Cai, Xiao-Yan Lin, Su Chen,  and Ewelina Biskup
77793-77806
Abstract  |  PDF  |  HTML  |  Order a Reprint

Somatostatin receptor based PET/CT in patients with the suspicion of cardiac sarcoidosis: an initial comparison to cardiac MRI

Somatostatin receptor based PET/CT in patients with the suspicion of cardiac sarcoidosis: an initial comparison to cardiac MRI

https://doi.org/10.18632/oncotarget.12799

Constantin Lapa, Theresa Reiter, Malte Kircher, Andreas Schirbel, Rudolf A. Werner, Theo Pelzer, Carmen Pizarro, Dirk Skowasch, Lena Thomas, Ulrike Schlesinger-Irsch, Daniel Thomas, Ralph A. Bundschuh, Wolfgang R. Bauer,  and Florian C. Gärtner
77807-77814
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pre-clinical characterization of PKC412, a multi-kinase inhibitor, against colorectal cancer cells

Pre-clinical characterization of PKC412, a multi-kinase inhibitor, against colorectal cancer cells

https://doi.org/10.18632/oncotarget.12802

Jian-Ping Li, Zhi-Jun Huang, Xing-Sheng Lu, Yi-Chan Zhou, Yun Shao, Xiao-Pu He, Su-Rong Chen, Dong-Dong Wang, Li-Sen Qin,  and Wei-Hao Sun
77815-77824
Abstract  |  PDF  |  HTML  |  Order a Reprint

Propranolol induces a favourable shift of anti-tumor immunity in a murine spontaneous model of melanoma

Propranolol induces a favourable shift of anti-tumor immunity in a murine spontaneous model of melanoma

https://doi.org/10.18632/oncotarget.12833

Ludovic Jean Wrobel, Lloyd Bod, Renée Lengagne, Masashi Kato, Armelle Prévost-Blondel,  and Frédérique-Anne Le Gal
77825-77837
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reg proteins promote acinar-to-ductal metaplasia and act as novel diagnostic and prognostic markers in pancreatic ductal adenocarcinoma

Reg proteins promote acinar-to-ductal metaplasia and act as novel diagnostic and prognostic markers in pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.12834

Qing Li, Hao Wang, George Zogopoulos, Qin Shao, Kun Dong, Fudong Lv, Karam Nwilati, Xian-yong Gui, Adeline Cuggia, Jun-Li Liu,  and Zu-hua Gao
77838-77853
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Serum APN/CD13 as a novel diagnostic and prognostic biomarker of pancreatic cancer

Serum APN/CD13 as a novel diagnostic and prognostic biomarker of pancreatic cancer

https://doi.org/10.18632/oncotarget.12835

Li Pang, Nan Zhang, Yan Xia, Dawei Wang, Guoqing Wang,  and Xiangwei Meng
77854-77864
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The intrinsically kinase-inactive EPHB6 receptor predisposes cancer cells to DR5-induced apoptosis by promoting mitochondrial fragmentation

The intrinsically kinase-inactive EPHB6 receptor predisposes cancer cells to DR5-induced apoptosis by promoting mitochondrial fragmentation

https://doi.org/10.18632/oncotarget.12838

Amr M. El Zawily, Behzad M. Toosi, Tanya Freywald, Vijaya V. Indukuri, Franco J. Vizeacoumar, Scot C. Leary,  and Andrew Freywald
77865-77877
Abstract  |  PDF  |  HTML  |  Order a Reprint

Association of vitamin D receptor Fok I polymorphism with the risk of prostate cancer: a meta-analysis

Association of vitamin D receptor Fok I polymorphism with the risk of prostate cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.12837

Shaosan Kang, Yansheng Zhao, Jian Liu, Lei Wang, Geng Zhao, Xi Chen, Anliang Yao, Liguo Zhang, Xiaojun Zhang,  and Xiaoqiang Li
77878-77889
Abstract  |  PDF  |  HTML  |  Order a Reprint

GATA4 promotes hepatoblastoma cell proliferation by altering expression of miR125b and DKK3

GATA4 promotes hepatoblastoma cell proliferation by altering expression of miR125b and DKK3

https://doi.org/10.18632/oncotarget.12839

Yihua Pei, Qin Yao, Sibo Yuan, Bozhen Xie, Yan Liu, Chunsheng Ye,  and Huiqin Zhuo
77890-77901
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PDGF-CC underlies resistance to VEGF-A inhibition and combinatorial targeting of both suppresses pathological angiogenesis more efficiently

PDGF-CC underlies resistance to VEGF-A inhibition and combinatorial targeting of both suppresses pathological angiogenesis more efficiently

https://doi.org/10.18632/oncotarget.12843

Lei Zheng, Chen Zhao, Yuxiang Du, Xianchai Lin, Yida Jiang, Chunsik Lee, Geng Tian, Jia Mi, Xianglin Li, Qishan Chen, Zhimin Ye, Lijuan Huang, Shasha Wang, Xiangrong Ren, Liying Xing, Wei Chen, Delong Huang, Zhiqin Gao, Shuping Zhang, Weisi Lu, Zhongshu Tang, Bin Wang, Rong Ju,  and Xuri Li
77902-77915
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pseudomonas aeruginosa-mannose-sensitive hemagglutinin inhibits pancreatic cancer cell proliferation and induces apoptosis via the EGFR pathway and caspase signaling

Pseudomonas aeruginosa-mannose-sensitive hemagglutinin inhibits pancreatic cancer cell proliferation and induces apoptosis via the EGFR pathway and caspase signaling

https://doi.org/10.18632/oncotarget.12844

Xi Cheng, Bingrui Wang, Zhijian Jin, Ding Ma, Weiping Yang, Ren Zhao, Xiaoqian Jing, Baiyong Shen, Chenghong Peng,  and Weihua Qiu
77916-77925
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting Enox1 in tumor stroma increases the efficacy of fractionated radiotherapy

Targeting Enox1 in tumor stroma increases the efficacy of fractionated radiotherapy

https://doi.org/10.18632/oncotarget.12845

Clayton A. Smith, Stacey Mont, Geri Traver, Konjeti R. Sekhar, Peter A. Crooks,  and Michael L. Freeman
77926-77936
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Multisite phosphorylation of P-Rex1 by protein kinase C

Multisite phosphorylation of P-Rex1 by protein kinase C

https://doi.org/10.18632/oncotarget.12846

Juan Carlos Montero, Samuel Seoane, Sara García-Alonso,  and Atanasio Pandiella
77937-77949
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic variants of MCP-1 and CCR2 genes and IgA nephropathy risk

Genetic variants of MCP-1 and CCR2 genes and IgA nephropathy risk

https://doi.org/10.18632/oncotarget.12847

Jie Gao, Xinghan Liu, Linting Wei, Dan Niu, Jiali Wei, Li Wang, Heng Ge, Meng Wang, Qiaoling Yu, Tianbo Jin, Tian Tian, Zhijun Dai,  and Rongguo Fu
77950-77957
Abstract  |  PDF  |  HTML  |  Order a Reprint

CD99 polymorphisms significantly influence the probability to develop Ewing sarcoma in earlier age and patient disease progression

CD99 polymorphisms significantly influence the probability to develop Ewing sarcoma in earlier age and patient disease progression

https://doi.org/10.18632/oncotarget.12862

Marcella Martinelli, Alessandro Parra, Luca Scapoli, Paola De Sanctis, Valentina Chiadini, Claudia Hattinger, Piero Picci, Cinzia Zucchini,  and Katia Scotlandi
77958-77967
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic variant in visfatin gene promoter contributes to reduced risk of hepatocellular carcinoma in a Chinese population

Genetic variant in visfatin gene promoter contributes to reduced risk of hepatocellular carcinoma in a Chinese population

https://doi.org/10.18632/oncotarget.12864

Zhitong Wu, Yifan Sun, Yiyong Huang, Shengbo Zhu, Yi Feng, Huifen Ye, Chunming Liu,  and Shifu Tang
77968-77977
Abstract  |  PDF  |  HTML  |  Order a Reprint

miR-135b-5p inhibits LPS-induced TNFα production via silencing AMPK phosphatase Ppm1e

miR-135b-5p inhibits LPS-induced TNFα production via silencing AMPK phosphatase Ppm1e

https://doi.org/10.18632/oncotarget.12866

Ping Li, Jian-bo Fan, Yanxia Gao, Ming Zhang, Li Zhang, Ning Yang,  and Xiaojing Zhao
77978-77986
Abstract  |  PDF  |  HTML  |  Order a Reprint

Vasculogenic mimicry in hepatocellular carcinoma contributes to portal vein invasion

Vasculogenic mimicry in hepatocellular carcinoma contributes to portal vein invasion

https://doi.org/10.18632/oncotarget.12867

Chen Jue, Wu Zhifeng, Zhang Zhisheng, Cui Lin, Qian Yayun, Jin Feng, Gu Hao, Ishikawa Shintaro, Tadashi Hisamitsu, Guo Shiyu,  and Liu Yanqing
77987-77997
Abstract  |  PDF  |  HTML  |  Order a Reprint

Evaluation of quantitative assays for the identification of direct signal transducer and activator of transcription 3 (STAT3) inhibitors

Evaluation of quantitative assays for the identification of direct signal transducer and activator of transcription 3 (STAT3) inhibitors

https://doi.org/10.18632/oncotarget.12868

Steffanie L. Furtek, Christopher J. Matheson, Donald S. Backos,  and Philip Reigan
77998-78008
Abstract  |  PDF  |  HTML  |  Order a Reprint

Methylation-associated silencing of microRNA-129-3p promotes epithelial-mesenchymal transition, invasion and metastasis of hepatocelluar cancer by targeting Aurora-A

Methylation-associated silencing of microRNA-129-3p promotes epithelial-mesenchymal transition, invasion and metastasis of hepatocelluar cancer by targeting Aurora-A

https://doi.org/10.18632/oncotarget.12870

Shiyun Cui, Kai Zhang, Chen Li, Jing Chen, Yan Pan, Bing Feng, Lei Lu, Ziman Zhu, Rui Wang,  and Longbang Chen
78009-78028
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HS-173, a novel PI3K inhibitor suppresses EMT and metastasis in pancreatic cancer

HS-173, a novel PI3K inhibitor suppresses EMT and metastasis in pancreatic cancer

https://doi.org/10.18632/oncotarget.12871

Marufa Rumman, Kyung Hee Jung, Zhenghuan Fang, Hong Hua Yan, Mi Kwon Son, Soo Jung Kim, Juyoung Kim, Jung Hee Park, Joo Han Lim, Sungwoo Hong,  and Soon-Sun Hong
78029-78047
Abstract  |  PDF  |  HTML  |  Order a Reprint

Elevation of C-reactive protein levels in patients with transfusion-related acute lung injury

Elevation of C-reactive protein levels in patients with transfusion-related acute lung injury

https://doi.org/10.18632/oncotarget.12872

Rick Kapur, Michael Kim, Matthew T. Rondina, Leendert Porcelijn,  and John W. Semple
78048-78054
Abstract  |  PDF  |  HTML  |  Order a Reprint

CREB1 directly activates the transcription of ribonucleotide reductase small subunit M2 and promotes the aggressiveness of human colorectal cancer

CREB1 directly activates the transcription of ribonucleotide reductase small subunit M2 and promotes the aggressiveness of human colorectal cancer

https://doi.org/10.18632/oncotarget.12938

Zejun Fang, Aifen Lin, Jiaoe Chen, Xiaomin Zhang, Hong Liu, Hongzhang Li, Yanyan Hu, Xia Zhang, Jiangang Zhang, Lanlan Qiu, Lingming Mei, Jimin Shao,  and Xiang Chen
78055-78068
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression of PKM2 promotes mitochondrial fusion through attenuated p53 stability

Overexpression of PKM2 promotes mitochondrial fusion through attenuated p53 stability

https://doi.org/10.18632/oncotarget.12942

Haili Wu, Peng Yang, Wanglai Hu, Yingying Wang, Yangxu Lu, Lichao Zhang, Yongsheng Fan, Hong Xiao,  and Zhuoyu Li
78069-78082
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Transposon-mediated generation of BCR-ABL1-expressing transgenic cell lines for unbiased sensitivity testing of tyrosine kinase inhibitors

Transposon-mediated generation of BCR-ABL1-expressing transgenic cell lines for unbiased sensitivity testing of tyrosine kinase inhibitors

https://doi.org/10.18632/oncotarget.12943

Konstantin Byrgazov, Chantal Blanche Lucini, Bettina Berkowitsch, Margit Koenig, Oskar A. Haas, Gregor Hoermann, Peter Valent,  and Thomas Lion
78083-78094
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Upregulation of miR-99a is associated with poor prognosis of acute myeloid leukemia and promotes myeloid leukemia cell expansion

Upregulation of miR-99a is associated with poor prognosis of acute myeloid leukemia and promotes myeloid leukemia cell expansion

https://doi.org/10.18632/oncotarget.12947

Xiaohui Si, Xiaoyun Zhang, Xing Hao, Yunan Li, Zizhen Chen, Yahui Ding, Hui Shi, Jie Bai, Yingdai Gao, Tao Cheng, Feng-Chun Yang,  and Yuan Zhou
78095-78109
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FEN1 gene variants confer reduced risk of breast cancer in chinese women: A case-control study

FEN1 gene variants confer reduced risk of breast cancer in chinese women: A case-control study

https://doi.org/10.18632/oncotarget.12948

Shuai Lin, Meng Wang, Xinghan Liu, Ye Lu, Zhuoqing Gong, Yan Guo, Pengtao Yang, Tian Tian, Cong Dai, Yi Zheng, Peng Xu, Shanli Li, Yuyao Zhu,  and Zhijun Dai
78110-78118
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dosimetric impact of multileaf collimator leaf width according to sophisticated grade of technique in the IMRT and VMAT planning for pituitary adenoma lesion

Dosimetric impact of multileaf collimator leaf width according to sophisticated grade of technique in the IMRT and VMAT planning for pituitary adenoma lesion

https://doi.org/10.18632/oncotarget.12974

Soo-Min Chae, Ki Woong Lee,  and Seok Hyun Son
78119-78126
Abstract  |  PDF  |  HTML  |  Order a Reprint

HUR protects NONO from degradation by mir320, which is induced by p53 upon UV irradiation

HUR protects NONO from degradation by mir320, which is induced by p53 upon UV irradiation

https://doi.org/10.18632/oncotarget.13002

Luigi Alfano, Caterina Costa, Antonella Caporaso, Dario Antonini, Antonio Giordano,  and Francesca Pentimalli
78127-78139
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

An imaging-based approach predicts clinical outcomes in prostate cancer through a novel support vector machine classification

An imaging-based approach predicts clinical outcomes in prostate cancer through a novel support vector machine classification

https://doi.org/10.18632/oncotarget.11293

Yu-Dong Zhang, Jing Wang, Chen-Jiang Wu, Mei-Ling Bao, Hai Li, Xiao-Ning Wang, Jun Tao,  and Hai-Bin Shi
78140-78151
Abstract  |  PDF  |  HTML  |  Order a Reprint

HER2 mutations in Chinese patients with non-small cell lung cancer

HER2 mutations in Chinese patients with non-small cell lung cancer

https://doi.org/10.18632/oncotarget.11313

Zhengbo Song, Xinmin Yu, Zhiyong Shi, Jun Zhao,  and Yiping Zhang
78152-78158
Abstract  |  PDF  |  HTML  |  Order a Reprint

Body mass index as a prognostic factor in patients with extranodal natural killer/T-cell lymphoma, nasal type

Body mass index as a prognostic factor in patients with extranodal natural killer/T-cell lymphoma, nasal type

https://doi.org/10.18632/oncotarget.11373

Jie Liu, Yao-Tiao Deng, Li Zhang, Na Li, Ming Jiang, Li-Qun Zou,  and Yu Jiang
78159-78167
Abstract  |  PDF  |  HTML  |  Order a Reprint

Diagnosis and treatment pattern among rural and urban breast cancer patients in Southwest China from 2005 to 2009

Diagnosis and treatment pattern among rural and urban breast cancer patients in Southwest China from 2005 to 2009

https://doi.org/10.18632/oncotarget.11375

Zuxiang Peng, Jia Wei, Xuesong Lu, Hong Zheng, Xiaorong Zhong, Weiguo Gao, Yunqin Chen,  and Jing Jing
78168-78179
Abstract  |  PDF  |  HTML  |  Order a Reprint

Management of advanced gastric cancer: An overview of major findings from meta-analysis

Management of advanced gastric cancer: An overview of major findings from meta-analysis

https://doi.org/10.18632/oncotarget.12102

Xiaolong Qi, Yanna Liu, Wei Wang, Danxian Cai, Wende Li, Jialiang Hui, Chuan Liu, Yanxia Zhao,  and Guoxin Li
78180-78205
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reviews

BMP signaling and its paradoxical effects in tumorigenesis and dissemination

BMP signaling and its paradoxical effects in tumorigenesis and dissemination

https://doi.org/10.18632/oncotarget.12151

Lijie Zhang, Yingnan Ye, Xinxin Long, Pei Xiao, Xiubao Ren,  and Jinpu Yu
78206-78218
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Corrections

Correction: Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high levels of phospho-Src

Correction: Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high levels of phospho-Src

https://doi.org/10.18632/oncotarget.13482

Marco Perez, Antonio Lucena-Cacace, Luis Miguel Marín-Gómez, Javier Padillo-Ruiz, Maria Jose Robles-Frias, Carmen Saez, Rocio Garcia-Carbonero,  and Amancio Carnero
78219-78219
Correction  |  PDF


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