Oncotarget

Vol 7, No 45

November 8, 2016

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About The Cover

The cover for issue 45 of Oncotarget features Figure 2A-2C, "Manhattan plot for candidate RNA editing SNPs among a) endometrioid cases (n = 1,439) versus controls (n = 21,693), b) mucinous cases (n = 696) versus controls, and c) clear cell cases (n = 660) versus controls," from Permuth, et al.

Table of Contents

Priority Research Papers

Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a large-scale collaboration

Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a large-scale collaboration

https://doi.org/10.18632/oncotarget.10546

Jennifer B. Permuth, Brett Reid, Madalene Earp, Y. Ann Chen, Alvaro NA. Monteiro, Zhihua Chen, AOCS Study Group, Georgia Chenevix-Trench, Peter A. Fasching, Matthias W. Beckmann, Diether Lambrechts, Adriaan Vanderstichele, Els Van Niewenhuyse, Ignace Vergote, Mary Anne Rossing, Jennifer Anne Doherty, Jenny Chang-Claude, Kirsten Moysich, Kunle Odunsi, Marc T. Goodman, Yurii B. Shvetsov, Lynne R. Wilkens, Pamela J. Thompson, Thilo Dörk, Natalia Bogdanova, Ralf Butzow, Heli Nevanlinna, Liisa Pelttari, Arto Leminen, Francesmary Modugno, Robert P. Edwards, Roberta B. Ness, Joseph Kelley, Florian Heitz, Beth Karlan, Jenny Lester, Susanne K. Kjaer, Allan Jensen, Graham Giles, Michelle Hildebrandt, Dong Liang, Karen H. Lu, Xifeng Wu, Douglas A. Levine, Maria Bisogna, Andrew Berchuck, Daniel W. Cramer, Kathryn L. Terry, Shelley S. Tworoger, Elizabeth M. Poole, Elisa V. Bandera, Brooke Fridley, Julie Cunningham, Stacey J. Winham, Sara H. Olson, Irene Orlow, Line Bjorge, Lambertus A. Kiemeney, Leon Massuger, Tanja Pejovic, Melissa Moffitt, Nhu Le, Linda S. Cook, Angela Brooks-Wilson, Linda E. Kelemen, Jacek Gronwald, Jan Lubinski, Nicolas Wentzensen, Louise A. Brinton, Jolanta Lissowska, Hanna Yang, Estrid Hogdall, Claus Hogdall, Lene Lundvall, Paul DP Pharoah, Honglin Song, Ian Campbell, Diana Eccles, Iain McNeish, Alice Whittemore, Valerie McGuire, Weiva Sieh, Joseph Rothstein, Catherine M. Phelan, Harvey Risch, Steven Narod, John McLaughlin, Hoda Anton-Culver, Argyrios Ziogas, Usha Menon, Simon Gayther, Susan J. Ramus, Aleksandra Gentry-Maharaj, Celeste Leigh Pearce, Anna H. Wu, Jolanta Kupryjanczyk, Agnieszka Dansonka-Mieszkowska, Joellen M. Schildkraut, Jin Q. Cheng, Ellen L. Goode,  and Thomas A. Sellers
72381-72394
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Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer

Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer

https://doi.org/10.18632/oncotarget.11718

Amanda R. Oran, Clare M. Adams, Xiao-yong Zhang, Victoria J. Gennaro, Harla K. Pfeiffer, Hestia S. Mellert, Hans E. Seidel, Kirsten Mascioli, Jordan Kaplan, Mahmoud R. Gaballa, Chen Shen, Isidore Rigoutsos, Michael P. King, Justin L. Cotney, Jamie J. Arnold, Suresh D. Sharma, Ubaldo E. Martinez-Outschoorn, Christopher R. Vakoc, Lewis A. Chodosh, James E. Thompson, James E. Bradner, Craig E. Cameron, Gerald S. Shadel, Christine M. Eischen,  and Steven B. McMahon
72395-72414
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The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas

The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas

https://doi.org/10.18632/oncotarget.11719

Aleco D’Andrea, Ilaria Gritti, Paola Nicoli, Marco Giorgio, Mirko Doni, Annalisa Conti, Valerio Bianchi, Lucia Casoli, Arianna Sabò, Alexandre Mironov, Galina V. Beznoussenko,  and Bruno Amati
72415-72430
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Research Papers: Gerotarget (Focus on Aging)

PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status

PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status

https://doi.org/10.18632/oncotarget.11957

Kenney R. Roodakker, Tamador Elsir, Per-Henrik D. Edqvist, Daniel Hägerstrand, Joseph Carlson, Malgorzata Lysiak, Roger Henriksson, Fredrik Pontén, Johan Rosell, Peter Söderkvist, Roger Stupp, Elena Tchougounova, Monica Nistér, Annika Malmström,  and Anja Smits
72431-72442
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A small molecule inhibitor of PAI-1 protects against doxorubicin-induced cellular senescence

A small molecule inhibitor of PAI-1 protects against doxorubicin-induced cellular senescence

https://doi.org/10.18632/oncotarget.12494

Asish K. Ghosh, Rahul Rai, Kitae E. Park, Mesut Eren, Toshio Miyata, Lisa D. Wilsbacher,  and Douglas E. Vaughan
72443-72457
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Baicalein protects against oxLDL-caused oxidative stress and inflammation by modulation of AMPK- alpha

Baicalein protects against oxLDL-caused oxidative stress and inflammation by modulation of AMPK- alpha

https://doi.org/10.18632/oncotarget.12788

Kun-Ling Tsai, Ching-Hsia Hung, Shih-Hung Chan, Jhih-Yuan Shih, Yung-Hsin Cheng, Yi-Ju Tsai, Huei-Chen Lin,  and Pei-Ming Chu
72458-72468
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Research Papers: Pathology

Gene expression analysis reveals the dysregulation of immune and metabolic pathways in Alzheimer’s disease

Gene expression analysis reveals the dysregulation of immune and metabolic pathways in Alzheimer’s disease

https://doi.org/10.18632/oncotarget.12505

Juan Chen, Chuncheng Xie, Yanhong Zhao, Zhiyan Li, Panpan Xu,  and Lifen Yao
72469-72474
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Toll-like 4 receptor /NFκB inflammatory/miR-146a pathway contributes to the ART-correlated preterm birth outcome

Toll-like 4 receptor /NFκB inflammatory/miR-146a pathway contributes to the ART-correlated preterm birth outcome

https://doi.org/10.18632/oncotarget.11987

Xinqi Zhong, Yi-Zhou Jiang, Peiwen Liu, Wenzhi He, Zhongtang Xiong, Weijie Chang, Jiandong Zhu,  and Qiliang Cui
72475-72485
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RNA binding protein, tristetraprolin in a murine model of recurrent pregnancy loss

RNA binding protein, tristetraprolin in a murine model of recurrent pregnancy loss

https://doi.org/10.18632/oncotarget.12539

Kasra Khalaj, Rayana Leal Luna, Maria Eduarda Rocha de França, Wilma Helena de Oliveira, Christina Alves Peixoto,  and Chandrakant Tayade
72486-72502
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Wogonin prevents TLR4-NF-κB-medicated neuro-inflammation and improves retinal ganglion cells survival in retina after optic nerve crush

Wogonin prevents TLR4-NF-κB-medicated neuro-inflammation and improves retinal ganglion cells survival in retina after optic nerve crush

https://doi.org/10.18632/oncotarget.12700

Yue Xu, Boyu Yang, Yaguang Hu, Lin Lu, Xi Lu, Jiawei Wang, Fan Xu, Shanshan Yu, Jingjing Huang,  and Xiaoling Liang
72503-72517
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Research Papers: Immunology

Proteomic analysis uncovers common effects of IFN-γ and IL-27 on the HLA class I antigen presentation machinery in human cancer cells

Proteomic analysis uncovers common effects of IFN-γ and IL-27 on the HLA class I antigen presentation machinery in human cancer cells

https://doi.org/10.18632/oncotarget.12235

Andrea Petretto, Grazia Carbotti, Elvira Inglese, Chiara Lavarello, Maria Pia Pistillo, Valentina Rigo, Michela Croce, Luca Longo, Stefania Martini, Paola Vacca, Silvano Ferrini,  and Marina Fabbi
72518-72536
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Umbilical cord-derived mesenchymal stem cells reversed the suppressive deficiency of T regulatory cells from peripheral blood of patients with multiple sclerosis in a co-culture – a preliminary study

Umbilical cord-derived mesenchymal stem cells reversed the suppressive deficiency of T regulatory cells from peripheral blood of patients with multiple sclerosis in a co-culture – a preliminary study

https://doi.org/10.18632/oncotarget.12345

Hongna Yang, Jinhua Sun, Feng Wang, Yan Li, Jianzhong Bi,  and Tingyu Qu
72537-72545
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A long noncoding RNA positively regulates CD56 in human natural killer cells

A long noncoding RNA positively regulates CD56 in human natural killer cells

https://doi.org/10.18632/oncotarget.12466

Ruya Zhang, Fang Ni, Binqing Fu, Yang Wu, Rui Sun, Zhigang Tian,  and Haiming Wei
72546-72558
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Generation of infectious RNA complexes in orbiviruses: RNA-RNA interactions of genomic segments

Generation of infectious RNA complexes in orbiviruses: RNA-RNA interactions of genomic segments

https://doi.org/10.18632/oncotarget.12496

Teodoro Fajardo Jr., Kinda AlShaikhahmed,  and Polly Roy
72559-72570
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Research Papers: Chromosome

ZSCAN5B and primate-specific paralogs bind RNA polymerase III genes and extra-TFIIIC (ETC) sites to modulate mitotic progression

ZSCAN5B and primate-specific paralogs bind RNA polymerase III genes and extra-TFIIIC (ETC) sites to modulate mitotic progression

https://doi.org/10.18632/oncotarget.12508

Younguk Sun, Huimin Zhang, Majid Kazemian, Joseph M. Troy, Christopher Seward, Xiaochen Lu,  and Lisa Stubbs
72571-72592
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Research Papers

Identification of miR-30b-3p and miR-30d-5p as direct regulators of androgen receptor signaling in prostate cancer by complementary functional microRNA library screening

Identification of miR-30b-3p and miR-30d-5p as direct regulators of androgen receptor signaling in prostate cancer by complementary functional microRNA library screening

https://doi.org/10.18632/oncotarget.12241

Binod Kumar, Salar Khaleghzadegan, Brian Mears, Koji Hatano, Tarana A. Kudrolli, Wasim H. Chowdhury, David B. Yeater, Charles M. Ewing, Jun Luo, William B. Isaacs, Luigi Marchionni,  and Shawn E. Lupold
72593-72607
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Janus and PI3-kinases mediate glucocorticoid resistance in activated chronic leukemia cells

Janus and PI3-kinases mediate glucocorticoid resistance in activated chronic leukemia cells

https://doi.org/10.18632/oncotarget.11618

Sina Oppermann, Avery J. Lam, Stephanie Tung, Yonghong Shi, Lindsay McCaw, Guizhei Wang, Jarkko Ylanko, Brian Leber, David Andrews,  and David E. Spaner
72608-72621
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Tumor and circulating biomarkers in patients with second-line hepatocellular carcinoma from the randomized phase II study with tivantinib

Tumor and circulating biomarkers in patients with second-line hepatocellular carcinoma from the randomized phase II study with tivantinib

https://doi.org/10.18632/oncotarget.11621

Lorenza Rimassa, Giovanni Abbadessa, Nicola Personeni, Camillo Porta, Ivan Borbath, Bruno Daniele, Stefania Salvagni, Jean-Luc Van Laethem, Hans Van Vlierberghe, Jörg Trojan, Enrico N. De Toni, Alan Weiss, Steven Miles, Antonio Gasbarrini, Monica Lencioni, Maria E. Lamar, Yunxia Wang, Dale Shuster, Brian E. Schwartz,  and Armando Santoro
72622-72633
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Smac mimetic LCL161 supports neuroblastoma chemotherapy in a drug class-dependent manner and synergistically interacts with ALK inhibitor TAE684 in cells with ALK mutation F1174L

Smac mimetic LCL161 supports neuroblastoma chemotherapy in a drug class-dependent manner and synergistically interacts with ALK inhibitor TAE684 in cells with ALK mutation F1174L

https://doi.org/10.18632/oncotarget.12055

Safiullah Najem, Doerte Langemann, Birgit Appl, Magdalena Trochimiuk, Patrick Hundsdoerfer, Konrad Reinshagen,  and Georg Eschenburg
72634-72653
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Biomarker analysis of the MITO2 phase III trial of first-line treatment in ovarian cancer: predictive value of DNA-PK and phosphorylated ACC

Biomarker analysis of the MITO2 phase III trial of first-line treatment in ovarian cancer: predictive value of DNA-PK and phosphorylated ACC

https://doi.org/10.18632/oncotarget.12056

Francesco Perrone, Gustavo Baldassarre, Stefano Indraccolo, Simona Signoriello, Gennaro Chiappetta, Franca Esposito, Gabriella Ferrandina, Renato Franco, Delia Mezzanzanica, Maura Sonego, Elisabetta Zulato, Gian F. Zannoni, Vincenzo Canzonieri, Giovanni Scambia, Roberto Sorio, Antonella Savarese, Enrico Breda, Paolo Scollo, Antonella Ferro, Stefano Tamberi, Antonio Febbraro, Donato Natale, Massimo Di Maio, Daniela Califano, Giosuè Scognamiglio, Domenica Lorusso, Silvana Canevari, Simona Losito, Ciro Gallo,  and Sandro Pignata
72654-72661
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IMP1, an mRNA binding protein that reduces the metastatic potential of breast cancer in a mouse model

IMP1, an mRNA binding protein that reduces the metastatic potential of breast cancer in a mouse model

https://doi.org/10.18632/oncotarget.12083

Chiso U. Nwokafor, Rani S. Sellers,  and Robert H. Singer
72662-72671
Abstract  |  PDF  |  HTML  |  Order a Reprint

Role of Dicer as a prognostic predictor for survival in cancer patients: a systematic review with a meta-analysis

Role of Dicer as a prognostic predictor for survival in cancer patients: a systematic review with a meta-analysis

https://doi.org/10.18632/oncotarget.12183

Wanying Shan, Chaoyang Sun, Bo Zhou, Ensong Guo, Hao Lu, Meng Xia, Kezhen Li, Danhui Weng, Xingguang Lin, Li Meng, Ding Ma,  and Gang Chen
72672-72684
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality

Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality

https://doi.org/10.18632/oncotarget.12234

Marios Dimitriou, Petter S. Woll, Teresa Mortera-Blanco, Mohsen Karimi, David C. Wedge, Helen Doolittle, Iyadh Douagi, Elli Papaemmanuil, Sten Eirik W. Jacobsen,  and Eva Hellström-Lindberg
72685-72698
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Interaction of microtubules with the actin cytoskeleton via cross-talk of EB1-containing +TIPs and γ-actin in epithelial cells

Interaction of microtubules with the actin cytoskeleton via cross-talk of EB1-containing +TIPs and γ-actin in epithelial cells

https://doi.org/10.18632/oncotarget.12236

Vera Dugina, Irina Alieva, Natalya Khromova, Igor Kireev, Peter W. Gunning,  and Pavel Kopnin
72699-72715
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Regulation of tumor growth by circulating full-length chromogranin A

Regulation of tumor growth by circulating full-length chromogranin A

https://doi.org/10.18632/oncotarget.12237

Flavio Curnis, Alice Dallatomasina, Mimma Bianco, Anna Gasparri, Angelina Sacchi, Barbara Colombo, Martina Fiocchi, Laura Perani, Massimo Venturini, Carlo Tacchetti, Suvajit Sen, Ricardo Borges, Eleonora Dondossola, Antonio Esposito, Sushil K. Mahata,  and Angelo Corti
72716-72732
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia

Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.12238

Adam J. de Smith, Juhi Ojha, Stephen S. Francis, Erica Sanders, Alyson A. Endicott, Helen M. Hansen, Ivan Smirnov, Amanda M. Termuhlen, Kyle M. Walsh, Catherine Metayer,  and Joseph L. Wiemels
72733-72745
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-26b attenuates monocrotaline-induced pulmonary vascular remodeling via targeting connective tissue growth factor (CTGF) and cyclin D1 (CCND1)

MicroRNA-26b attenuates monocrotaline-induced pulmonary vascular remodeling via targeting connective tissue growth factor (CTGF) and cyclin D1 (CCND1)

https://doi.org/10.18632/oncotarget.10125

Ran Wang, Xing Ding, Sijing Zhou, Min Li, Li Sun, Xuan Xu,  and Guanghe Fei
72746-72757
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Computational identification of microRNAs associated to both epithelial to mesenchymal transition and NGAL/MMP-9 pathways in bladder cancer

Computational identification of microRNAs associated to both epithelial to mesenchymal transition and NGAL/MMP-9 pathways in bladder cancer

https://doi.org/10.18632/oncotarget.11805

Luca Falzone, Saverio Candido, Rossella Salemi, Maria S. Basile, Aurora Scalisi, James A. McCubrey, Francesco Torino, Salvatore S. Signorelli, Maurizio Montella,  and Massimo Libra
72758-72766
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Aberrant expression of KPNA2 is associated with a poor prognosis and contributes to OCT4 nuclear transportation in bladder cancer

Aberrant expression of KPNA2 is associated with a poor prognosis and contributes to OCT4 nuclear transportation in bladder cancer

https://doi.org/10.18632/oncotarget.11889

Jingcheng Zhou, Daoquan Dong, Ran Cheng, Yan Wang, Shuqi Jiang, Yuhong Zhu, Longlong Fan, Xiangming Mao, Yaoting Gui, Zesong Li, Xianxin Li,  and Bentao Shi
72767-72776
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c-Abl inhibits breast cancer tumorigenesis through reactivation of p53-mediated p21 expression

c-Abl inhibits breast cancer tumorigenesis through reactivation of p53-mediated p21 expression

https://doi.org/10.18632/oncotarget.11909

Chevaun D. Morrison, Tressa M. Allington, Cheryl L. Thompson, Hannah L. Gilmore, Jenny C. Chang, Ruth A. Keri,  and William P. Schiemann
72777-72794
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DRG1 is a potential oncogene in lung adenocarcinoma and promotes tumor progression via spindle checkpoint signaling regulation

DRG1 is a potential oncogene in lung adenocarcinoma and promotes tumor progression via spindle checkpoint signaling regulation

https://doi.org/10.18632/oncotarget.11973

Li Lu, Yanrong Lv, Ji Dong, Shaohua Hu,  and Ruiyun Peng
72795-72806
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SASH1 mediates sensitivity of breast cancer cells to chloropyramine and is associated with prognosis in breast cancer

SASH1 mediates sensitivity of breast cancer cells to chloropyramine and is associated with prognosis in breast cancer

https://doi.org/10.18632/oncotarget.12020

Joshua T. Burgess, Emma Bolderson, Jodi M. Saunus, Shu-Dong Zhang, Lynne E. Reid, Anne Marie McNicol, Sunil R. Lakhani, Katharine Cuff, Kerry Richard, Derek J. Richard,  and Kenneth J. O’Byrne
72807-72818
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Prognostic role and correlation of CA9, CD31, CD68 and CD20 with the desmoplastic stroma in pancreatic ductal adenocarcinoma

Prognostic role and correlation of CA9, CD31, CD68 and CD20 with the desmoplastic stroma in pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.12022

Angela Diana, Lai Mun Wang, Zenobia D’Costa, Abul Azad, Michael A. Silva, Zahir Soonawalla, Paul Allen, Stanley Liu, W. Gillies McKenna, Ruth J. Muschel,  and Emmanouil Fokas
72819-72832
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Long non-coding RNA CRNDE promotes gallbladder carcinoma carcinogenesis and as a scaffold of DMBT1 and C-IAP1 complexes to activating PI3K-AKT pathway

Long non-coding RNA CRNDE promotes gallbladder carcinoma carcinogenesis and as a scaffold of DMBT1 and C-IAP1 complexes to activating PI3K-AKT pathway

https://doi.org/10.18632/oncotarget.12023

Sheng Shen, Han Liu, Yueqi Wang, Jiwen Wang, Xiaolin Ni, Zhilong Ai, Hongtao Pan, Houbao Liu,  and Yebo Shao
72833-72844
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Aberrant expression of JNK-associated leucine-zipper protein, JLP, promotes accelerated growth of ovarian cancer

Aberrant expression of JNK-associated leucine-zipper protein, JLP, promotes accelerated growth of ovarian cancer

https://doi.org/10.18632/oncotarget.12069

Ji Hee Ha, Mingda Yan, Rohini Gomathinayagam, Muralidharan Jayaraman, Sanam Husain, Jinsong Liu, Priyabrata Mukherjee, E. Premkumar Reddy, Yong Sang Song,  and Danny N. Dhanasekaran
72845-72859
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Comprehensive adipocytic and neurogenic tissue microarray analysis of NY-ESO-1 expression - a promising immunotherapy target in malignant peripheral nerve sheath tumor and liposarcoma

Comprehensive adipocytic and neurogenic tissue microarray analysis of NY-ESO-1 expression - a promising immunotherapy target in malignant peripheral nerve sheath tumor and liposarcoma

https://doi.org/10.18632/oncotarget.12096

Elizabeth Shurell, Maria E. Vergara-Lluri, Yunfeng Li, Joseph G. Crompton, Arun Singh, Nicholas Bernthal, Hong Wu, Fritz C. Eilber,  and Sarah M. Dry
72860-72867
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Antitumor activity of a novel anti-vascular endothelial growth factor receptor-1 monoclonal antibody that does not interfere with ligand binding

Antitumor activity of a novel anti-vascular endothelial growth factor receptor-1 monoclonal antibody that does not interfere with ligand binding

https://doi.org/10.18632/oncotarget.12108

Grazia Graziani, Federica Ruffini, Lucio Tentori, Manuel Scimeca, Annalisa S. Dorio, Maria Grazia Atzori, Cristina M. Failla, Veronica Morea, Elena Bonanno, Stefania D’Atri,  and Pedro M. Lacal
72868-72885
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Synergistic activity of ALK and mTOR inhibitors for the treatment of NPM-ALK positive lymphoma

Synergistic activity of ALK and mTOR inhibitors for the treatment of NPM-ALK positive lymphoma

https://doi.org/10.18632/oncotarget.12128

Sara Redaelli, Monica Ceccon, Laura Antolini, Roberta Rigolio, Alessandra Pirola, Marco Peronaci, Carlo Gambacorti-Passerini,  and Luca Mologni
72886-72897
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Prognostic role of the lymph node ratio in node positive colorectal cancer: a meta-analysis

Prognostic role of the lymph node ratio in node positive colorectal cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.12131

Ming-Ran Zhang, Tian-Hang Xie, Jun-Lin Chi, Yuan Li, Lie Yang, Yong-Yang Yu, Xiao-Feng Sun,  and Zong-Guang Zhou
72898-72907
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Genomic characterization of liver metastases from colorectal cancer patients

Genomic characterization of liver metastases from colorectal cancer patients

https://doi.org/10.18632/oncotarget.12140

José María Sayagués, Luís Antonio Corchete, María Laura Gutiérrez, Maria Eugenia Sarasquete, María del Mar Abad, Oscar Bengoechea, Encarna Fermiñán, María Fernanda Anduaga, Sofia del Carmen, Manuel Iglesias, Carmen Esteban, María Angoso, Jose Antonio Alcazar, Jacinto García, Alberto Orfao,  and Luís Muñoz-Bellvis
72908-72922
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Grp94 in complexes with IgG is a soluble diagnostic marker of gastrointestinal tumors and displays immune-stimulating activity on peripheral blood immune cells

Grp94 in complexes with IgG is a soluble diagnostic marker of gastrointestinal tumors and displays immune-stimulating activity on peripheral blood immune cells

https://doi.org/10.18632/oncotarget.12141

Elisa Tramentozzi, Erlis Ruli, Imerio Angriman, Romeo Bardini, Michela Campora, Vincenza Guzzardo, Rita Zamarchi, Elisabetta Rossi, Massimo Rugge,  and Paola Finotti
72923-72940
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Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway

Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway

https://doi.org/10.18632/oncotarget.12146

Rui Cao, Zhe Meng, Tongzu Liu, Gang Wang, Guofeng Qian, Tingting Cao, Xinyuan Guan, Hancai Dan, Yu Xiao,  and Xinghuan Wang
72941-72960
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PD-1 mediates functional exhaustion of activated NK cells in patients with Kaposi sarcoma

PD-1 mediates functional exhaustion of activated NK cells in patients with Kaposi sarcoma

https://doi.org/10.18632/oncotarget.12150

Asma Beldi-Ferchiou, Marion Lambert, Stéphanie Dogniaux, Frédéric Vély, Eric Vivier, Daniel Olive, Stéphanie Dupuy, Frank Levasseur, David Zucman, Céleste Lebbé, Damien Sène, Claire Hivroz,  and Sophie Caillat-Zucman
72961-72977
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Multi-cycle chemotherapy with the glycolipid-like polymeric micelles evade cancer stem cell enrichment in breast cancer therapy

Multi-cycle chemotherapy with the glycolipid-like polymeric micelles evade cancer stem cell enrichment in breast cancer therapy

https://doi.org/10.18632/oncotarget.12159

Tingting Meng, Jingwen Liu, Lijuan Wen, Ming Yuan, Bolin Cheng, Yingwen Hu, Yun Zhu, Xuan Liu, Hong Yuan,  and Fuqiang Hu
72978-72989
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Geridonin and paclitaxel act synergistically to inhibit the proliferation of gastric cancer cells through ROS-mediated regulation of the PTEN/PI3K/Akt pathway

Geridonin and paclitaxel act synergistically to inhibit the proliferation of gastric cancer cells through ROS-mediated regulation of the PTEN/PI3K/Akt pathway

https://doi.org/10.18632/oncotarget.12166

Sai-Qi Wang, Cong Wang, Li-Ming Chang, Kai-Rui Zhou, Jun-Wei Wang, Yu Ke, Dong-Xiao Yang, Hong-Ge Shi, Ran Wang, Xiao-Li Shi, Li-Ying Ma,  and Hong-Min Liu
72990-73002
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevated level of Interleukin-35 in colorectal cancer induces conversion of T cells into iTr35 by activating STAT1/STAT3

Elevated level of Interleukin-35 in colorectal cancer induces conversion of T cells into iTr35 by activating STAT1/STAT3

https://doi.org/10.18632/oncotarget.12193

Yanhui Ma, Lei Chen, Guohua Xie, Yunlan Zhou, Chaoyan Yue, Xiangliang Yuan, Yingxia Zheng, Weiwei Wang, Lin Deng,  and Lisong Shen
73003-73015
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting cancer initiating cells by promoting cell differentiation and restoring chemosensitivity via dual inactivation of STAT3 and Src activity using an active component of Antrodia cinnamomea mycelia

Targeting cancer initiating cells by promoting cell differentiation and restoring chemosensitivity via dual inactivation of STAT3 and Src activity using an active component of Antrodia cinnamomea mycelia

https://doi.org/10.18632/oncotarget.12194

Ching-Wen Chang, Yu-Syuan Chen, Chien-Chih Chen, Ik-On Chan, Chin-Chu Chen, Sen-Je Sheu, Ting-wei Lin, Shiu-Huey Chou, Chung-Ji Liu, Te-Chang Lee,  and Jeng-Fan Lo
73016-73031
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overcoming adaptive resistance in mucoepidermoid carcinoma through inhibition of the IKK-β/IκBα/NFκB axis

Overcoming adaptive resistance in mucoepidermoid carcinoma through inhibition of the IKK-β/IκBα/NFκB axis

https://doi.org/10.18632/oncotarget.12195

Vivian P. Wagner, Marco A.T. Martins, Manoela D. Martins, Kristy A. Warner, Liana P. Webber, Cristiane H. Squarize, Jacques E. Nör,  and Rogerio M. Castilho
73032-73044
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Tumour suppressor gene (CDKNA2) status on chromosome 9p in resected renal tissue improves prognosis of localised kidney cancer

Tumour suppressor gene (CDKNA2) status on chromosome 9p in resected renal tissue improves prognosis of localised kidney cancer

https://doi.org/10.18632/oncotarget.12196

Ismail El-Mokadem, Thomas Kidd, Norman Pratt, Stewart Fleming,  and Ghulam Nabi
73045-73054
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The C-terminal domain of connexin43 modulates cartilage structure via chondrocyte phenotypic changes

The C-terminal domain of connexin43 modulates cartilage structure via chondrocyte phenotypic changes

https://doi.org/10.18632/oncotarget.12197

Raquel Gago-Fuentes, John F. Bechberger, Marta Varela-Eirin, Adrian Varela-Vazquez, Benigno Acea, Eduardo Fonseca, Christian C. Naus,  and Maria D. Mayan
73055-73067
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The efficacy and safety of anti-PD-1/PD-L1 antibodies for treatment of advanced or refractory cancers: a meta-analysis

The efficacy and safety of anti-PD-1/PD-L1 antibodies for treatment of advanced or refractory cancers: a meta-analysis

https://doi.org/10.18632/oncotarget.12230

Tengfei Zhang, Jing Xie, Seiji Arai, Liping Wang, Xuezhong Shi, Ni Shi, Fen Ma, Sen Chen, Lan Huang, Li Yang, Wang Ma, Bin Zhang, Weidong Han, Jianchuan Xia, Hu Chen,  and Yi Zhang
73068-73079
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways

Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways

https://doi.org/10.18632/oncotarget.11485

Pamela Ovadje, Saleem Ammar, Jose-Antonio Guerrero, John Thor Arnason,  and Siyaram Pandey
73080-73100
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The role of SH3GL3 in myeloma cell migration/invasion, stemness and chemo-resistance

The role of SH3GL3 in myeloma cell migration/invasion, stemness and chemo-resistance

https://doi.org/10.18632/oncotarget.12231

Ruoying Chen, Hong Zhao, Dan Wu, Chen Zhao, Weiling Zhao,  and Xiaobo Zhou
73101-73113
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A novel co-drug of aspirin and ursolic acid interrupts adhesion, invasion and migration of cancer cells to vascular endothelium via regulating EMT and EGFR-mediated signaling pathways: multiple targets for cancer metastasis prevention and treatment

A novel co-drug of aspirin and ursolic acid interrupts adhesion, invasion and migration of cancer cells to vascular endothelium via regulating EMT and EGFR-mediated signaling pathways: multiple targets for cancer metastasis prevention and treatment

https://doi.org/10.18632/oncotarget.12232

Qiao Tang, Yajun Liu, Tao Li, Xiang Yang, Guirong Zheng, Hongning Chen, Lee Jia,  and Jingwei Shao
73114-73129
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Intraglomerular crosstalk elaborately regulates podocyte injury and repair in diabetic patients: insights from a 3D multiscale modeling study

Intraglomerular crosstalk elaborately regulates podocyte injury and repair in diabetic patients: insights from a 3D multiscale modeling study

https://doi.org/10.18632/oncotarget.12233

Hua Tan, Hualin Yi, Weiling Zhao, Jian-Xing Ma, Yuanyuan Zhang,  and Xiaobo Zhou
73130-73146
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Adipocytes cause leukemia cell resistance to daunorubicin via oxidative stress response

Adipocytes cause leukemia cell resistance to daunorubicin via oxidative stress response

https://doi.org/10.18632/oncotarget.12246

Xia Sheng, Jonathan Tucci, Jean-Hugues Parmentier, Lingyun Ji, James W. Behan, Nora Heisterkamp,  and Steven D. Mittelman
73147-73159
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cyr61-positive cancer stem-like cells enhances distal metastases of pancreatic cancer

Cyr61-positive cancer stem-like cells enhances distal metastases of pancreatic cancer

https://doi.org/10.18632/oncotarget.12248

Weidong Shi, Chenyue Zhang, Zhen Chen, Hao Chen, Luming Liu,  and Zhiqiang Meng
73160-73170
Abstract  |  PDF  |  HTML  |  Order a Reprint

Expression of the TPα and TPβ isoforms of the thromboxane prostanoid receptor (TP) in prostate cancer: clinical significance and diagnostic potential

Expression of the TPα and TPβ isoforms of the thromboxane prostanoid receptor (TP) in prostate cancer: clinical significance and diagnostic potential

https://doi.org/10.18632/oncotarget.12256

Eamon P. Mulvaney, Christine Shilling, Sarah B. Eivers, Antoinette S. Perry, Anders Bjartell, Elaine W. Kay, R. William Watson,  and B. Therese Kinsella
73171-73187
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MiR-128 reverses the gefitinib resistance of the lung cancer stem cells by inhibiting the c-met/PI3K/AKT pathway

MiR-128 reverses the gefitinib resistance of the lung cancer stem cells by inhibiting the c-met/PI3K/AKT pathway

https://doi.org/10.18632/oncotarget.12283

Jingjin Jiang, Xiaoning Feng, Wenjing Zhou, Yue Wu,  and Yunmei Yang
73188-73199
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Case-specific potentiation of glioblastoma drugs by pterostilbene

Case-specific potentiation of glioblastoma drugs by pterostilbene

https://doi.org/10.18632/oncotarget.12298

Linnéa Schmidt, Sathishkumar Baskaran, Patrik Johansson, Narendra Padhan, Damian Matuszewski, Lydia C Green, Ludmila Elfineh, Shimei Wee, Maria Häggblad, Ulf Martens, Bengt Westermark, Karin Forsberg-Nilsson, Lene Uhrbom, Lena Claesson-Welsh, Michael Andäng, Ida-Maria Sintorn, Bo Lundgren, Ingrid Lönnstedt, Cecilia Krona,  and Sven Nelander
73200-73215
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ADH1B and CDH1 polymorphisms predict prognosis in male patients with non-metastatic laryngeal cancer

ADH1B and CDH1 polymorphisms predict prognosis in male patients with non-metastatic laryngeal cancer

https://doi.org/10.18632/oncotarget.12301

Daxu Li, Ruizhi Zhang, Tianbo Jin, Na He, Le Ren, Zhe Zhang, Qingna Zhang, Ran Xu, Hong Tao, Guang Zeng,  and Jing Gao
73216-73228
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Enhancement of endothelial permeability by free fatty acid through lysosomal cathepsin B-mediated Nlrp3 inflammasome activation

Enhancement of endothelial permeability by free fatty acid through lysosomal cathepsin B-mediated Nlrp3 inflammasome activation

https://doi.org/10.18632/oncotarget.12302

Lei Wang, Yang Chen, Xiang Li, Youzhi Zhang, Erich Gulbins,  and Yang Zhang
73229-73241
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Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-κB in esophageal squamous cell carcinoma cells

Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-κB in esophageal squamous cell carcinoma cells

https://doi.org/10.18632/oncotarget.12303

Won-Sik Shin, Yuri Hong, Hae Won Lee,  and Seung-Taek Lee
73242-73256
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

An artificial lncRNA targeting multiple miRNAs overcomes sorafenib resistance in hepatocellular carcinoma cells

An artificial lncRNA targeting multiple miRNAs overcomes sorafenib resistance in hepatocellular carcinoma cells

https://doi.org/10.18632/oncotarget.12304

Shuyao Tang, Gang Tan, Xian Jiang, Peng Han, Bo Zhai, Xuesong Dong, Haiquan Qiao, Hongchi Jiang,  and Xueying Sun
73257-73269
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Low carbohydrate diet prevents Mcl-1-mediated resistance to BH3-mimetics

Low carbohydrate diet prevents Mcl-1-mediated resistance to BH3-mimetics

https://doi.org/10.18632/oncotarget.12309

Camila Rubio-Patiño, Jozef P. Bossowski, Elodie Villa, Laura Mondragón, Barbara Zunino, Emma Proïcs, Johanna Chiche, Frédéric Bost, Els Verhoeyen,  and Jean-Ehrland Ricci
73270-73279
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Thermo-sensitive composite hydrogels based on poloxamer 407 and alginate and their therapeutic effect in embolization in rabbit VX2 liver tumors

Thermo-sensitive composite hydrogels based on poloxamer 407 and alginate and their therapeutic effect in embolization in rabbit VX2 liver tumors

https://doi.org/10.18632/oncotarget.11789

Lili Huang, Ming Shen, Rongxin Li, Xiangyu Zhang, Ying Sun, Pei Gao, Hao Fu, Hongqiang Liu, Yang He, Yuqing Du, Jun Cao,  and Yourong Duan
73280-73291
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Co-application of canavanine and irradiation uncouples anticancer potential of arginine deprivation from citrulline availability

Co-application of canavanine and irradiation uncouples anticancer potential of arginine deprivation from citrulline availability

https://doi.org/10.18632/oncotarget.12320

Yuliya Kurlishchuk, Bozhena Vynnytska-Myronovska, Philipp Grosse-Gehling, Yaroslav Bobak, Friederike Manig, Oleg Chen, Sebastian R. Merker, Thomas Henle, Steffen Löck, Daniel E. Stange, Oleh Stasyk,  and Leoni A. Kunz-Schughart
73292-73308
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Keratin 18-deficiency results in steatohepatitis and liver tumors in old mice: A model of steatohepatitis-associated liver carcinogenesis

Keratin 18-deficiency results in steatohepatitis and liver tumors in old mice: A model of steatohepatitis-associated liver carcinogenesis

https://doi.org/10.18632/oncotarget.12325

Kira Bettermann, Anita Kuldeep Mehta, Eva M. Hofer, Christina Wohlrab, Nicole Golob-Schwarzl, Vendula Svendova, Michael G. Schimek, Cornelia Stumptner, Andrea Thüringer, Michael R. Speicher, Carolin Lackner, Kurt Zatloukal, Helmut Denk,  and Johannes Haybaeck
73309-73322
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

p53 in the mitochondria, as a trans-acting protein, provides error-correction activities during the incorporation of non-canonical dUTP into DNA

p53 in the mitochondria, as a trans-acting protein, provides error-correction activities during the incorporation of non-canonical dUTP into DNA

https://doi.org/10.18632/oncotarget.12331

Elad Bonda, Galia Rahav, Angelina Kaya,  and Mary Bakhanashvili
73323-73336
Abstract  |  PDF  |  HTML  |  Order a Reprint

ERBB2 mutations associated with solid variant of high-grade invasive lobular breast carcinomas

ERBB2 mutations associated with solid variant of high-grade invasive lobular breast carcinomas

https://doi.org/10.18632/oncotarget.11819

Gabrielle Deniziaut, Jean Christophe Tille, François-Clément Bidard, Sophie Vacher, Anne Schnitzler, Walid Chemlali, Laurence Tremoulet, Laetitia Fuhrmann, Paul Cottu, Roman Rouzier, Ivan Bièche,  and Anne Vincent-Salomon
73337-73346
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Promoter methylation patterns of ABCB1, ABCC1 and ABCG2 in human cancer cell lines, multidrug-resistant cell models and tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients

Promoter methylation patterns of ABCB1, ABCC1 and ABCG2 in human cancer cell lines, multidrug-resistant cell models and tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients

https://doi.org/10.18632/oncotarget.12332

Melanie Spitzwieser, Christine Pirker, Bettina Koblmüller, Georg Pfeiler, Stefan Hacker, Walter Berger, Petra Heffeter,  and Margit Cichna-Markl
73347-73369
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CARP-1 functional mimetics are novel inhibitors of drug-resistant triple negative breast cancers

CARP-1 functional mimetics are novel inhibitors of drug-resistant triple negative breast cancers

https://doi.org/10.18632/oncotarget.12333

Vino T. Cheriyan, Magesh Muthu, Ketan Patel, Sreeja Sekhar, Walajapet Rajeswaran, Scott D. Larsen, Lisa Polin, Edi Levi, Mandip Singh,  and Arun K. Rishi
73370-73388
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LKB1 is a DNA damage response protein that regulates cellular sensitivity to PARP inhibitors

LKB1 is a DNA damage response protein that regulates cellular sensitivity to PARP inhibitors

https://doi.org/10.18632/oncotarget.12334

Yi-Shu Wang, Jianfeng Chen, Fengmei Cui, Huibo Wang, Shuai Wang, Wei Hang, Qinghua Zeng, Cheng-Shi Quan, Ying-Xian Zhai, Jian-Wei Wang, Xiang-Feng Shen, Yong-Ping Jian, Rui-Xun Zhao, Kaitlin D. Werle, Rutao Cui, Jiyong Liang, Yu-Lin Li,  and Zhi-Xiang Xu
73389-73401
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Asporin enhances colorectal cancer metastasis through activating the EGFR/Src/cortactin signaling pathway

Asporin enhances colorectal cancer metastasis through activating the EGFR/Src/cortactin signaling pathway

https://doi.org/10.18632/oncotarget.12336

Huo Wu, Xiaoqian Jing, Xi Cheng, Yonggang He, Lei Hu, Haoxuan Wu, Feng Ye,  and Ren Zhao
73402-73413
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reciprocal regulation of the cholinic phenotype and epithelial-mesenchymal transition in glioblastoma cells

Reciprocal regulation of the cholinic phenotype and epithelial-mesenchymal transition in glioblastoma cells

https://doi.org/10.18632/oncotarget.12337

Katharina Koch, Rudolf Hartmann, Friederike Schröter, Abigail Kora Suwala, Donata Maciaczyk, Andrea Caroline Krüger, Dieter Willbold, Ulf Dietrich Kahlert,  and Jaroslaw Maciaczyk
73414-73431
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice

Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice

https://doi.org/10.18632/oncotarget.12369

Chi-Hao Wu, Hsin-Yuan Chen, Chia-Woei Wang, Tzong-Ming Shieh, Tsui-Chin Huang, Li-Chun Lin, Kai-Lee Wang,  and Shih-Min Hsia
73432-73447
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Low-dose salinomycin induces anti-leukemic responses in AML and MLL

Low-dose salinomycin induces anti-leukemic responses in AML and MLL

https://doi.org/10.18632/oncotarget.11866

Gary D.R. Roulston, Charlotte L. Burt, Laura M.J. Kettyle, Kyle B. Matchett, Heather L. Keenan, Nuala M. Mulgrew, Joanne M. Ramsey, Caoifa Dougan, John McKiernan, Ivan V. Grishagin, Ken I. Mills,  and Alexander Thompson
73448-73461
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GPR30 disrupts the balance of GABAergic and glutamatergic transmission in the spinal cord driving to the development of bone cancer pain

GPR30 disrupts the balance of GABAergic and glutamatergic transmission in the spinal cord driving to the development of bone cancer pain

https://doi.org/10.18632/oncotarget.11867

Jie Luo, Xiaoxia Huang, Yali Li, Yang Li, Xueqin Xu, Yan Gao, Ruoshi Shi, Wanjun Yao, Juying Liu,  and Changbin Ke
73462-73472
Abstract  |  PDF  |  HTML  |  Order a Reprint

Recombinant human bone morphogenetic protein-2 inhibits gastric cancer cell proliferation by inactivating Wnt signaling pathway via c-Myc with aurora kinases

Recombinant human bone morphogenetic protein-2 inhibits gastric cancer cell proliferation by inactivating Wnt signaling pathway via c-Myc with aurora kinases

https://doi.org/10.18632/oncotarget.11969

Kwang Bok Lee, Hua Jin, Shuai Ye, Byung Hyun Park,  and Soo Mi Kim
73473-73485
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oxidized macrophage migration inhibitory factor is a potential new tissue marker and drug target in cancer

Oxidized macrophage migration inhibitory factor is a potential new tissue marker and drug target in cancer

https://doi.org/10.18632/oncotarget.11970

Alexander Schinagl, Michael Thiele, Patrice Douillard, Dirk Völkel, Lukas Kenner, Zahra Kazemi, Michael Freissmuth, Friedrich Scheiflinger,  and Randolf J. Kerschbaumer
73486-73496
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Piperlongumine induces apoptosis and reduces bortezomib resistance by inhibiting STAT3 in multiple myeloma cells

Piperlongumine induces apoptosis and reduces bortezomib resistance by inhibiting STAT3 in multiple myeloma cells

https://doi.org/10.18632/oncotarget.11988

Yao Yao, Yueyue Sun, Min Shi, Dandan Xia, Kai Zhao, Lingyu Zeng, Ruosi Yao, Ying Zhang, Zhenyu Li, Mingshan Niu,  and Kailin Xu
73497-73508
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Integrating microRNA and mRNA expression profiles of acute promyelocytic leukemia cells to explore the occurrence mechanisms of differentiation syndrome

Integrating microRNA and mRNA expression profiles of acute promyelocytic leukemia cells to explore the occurrence mechanisms of differentiation syndrome

https://doi.org/10.18632/oncotarget.11989

Yingmei Zhang, Jinxiao Hou, Fei Ge, Fenglin Cao, Haitao Li, Ping Wang, Mengyuan Xu, Peng Song, Xiaoxia Li, Shuye Wang, Jinmei Li, Xueying Han, Yanhong Zhao, Yanhua Su, Yinghua Li, Shengjin Fan, Limin Li,  and Jin Zhou
73509-73524
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation

Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation

https://doi.org/10.18632/oncotarget.12321

Elmer Hoekstra, Asha M. Das, Marcella Willemsen, Marloes Swets, Peter J.K. Kuppen, Christien J. van der Woude, Marco J. Bruno, Jigisha P. Shah, Timo L.M. ten Hagen, John D. Chisholm, William G. Kerr, Maikel P. Peppelenbosch,  and Gwenny M. Fuhler
73525-73540
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of long non-coding RNAs biomarkers for early diagnosis of myocardial infarction from the dysregulated coding-non-coding co-expression network

Identification of long non-coding RNAs biomarkers for early diagnosis of myocardial infarction from the dysregulated coding-non-coding co-expression network

https://doi.org/10.18632/oncotarget.11999

Chaoyu Sun, Hao Jiang, Zhiguo Sun, Yifang Gui,  and Hongyuan Xia
73541-73551
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Matrix metalloproteinase-13 refines pathological staging of precancerous colorectal lesions

Matrix metalloproteinase-13 refines pathological staging of precancerous colorectal lesions

https://doi.org/10.18632/oncotarget.12429

Anna-Katharina Wernicke, Yuri Churin, Diana Sheridan, Anita Windhorst, Annette Tschuschner, Stefan Gattenlöhner, Martin Roderfeld,  and Elke Roeb
73552-73557
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CCND1 mutations increase protein stability and promote ibrutinib resistance in mantle cell lymphoma

CCND1 mutations increase protein stability and promote ibrutinib resistance in mantle cell lymphoma

https://doi.org/10.18632/oncotarget.12434

Atish Mohanty, Natalie Sandoval, Manasi Das, Raju Pillai, Lu Chen, Robert W. Chen, Hesham M. Amin, Michael Wang, Guido Marcucci, Dennis D. Weisenburger, Steven T. Rosen, Lan V. Pham,  and Vu N. Ngo
73558-73572
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Flavan-3-ols consumption and cancer risk: a meta-analysis of epidemiologic studies

Flavan-3-ols consumption and cancer risk: a meta-analysis of epidemiologic studies

https://doi.org/10.18632/oncotarget.12017

Lei Lei, Ying Yang, Hongiuan He, Erfei Chen, Le Du, Jing Dong,  and Jin Yang
73573-73592
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction

NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction

https://doi.org/10.18632/oncotarget.12435

Chao Zhang, Hui-Jie Wang, Qi-Chao Bao, Lei Wang, Tian-Kun Guo, Wei-Lin Chen, Li-Li Xu, Hai-Shan Zhou, Jin-Lei Bian, Ying-Rui Yang, Hao-Peng Sun, Xiao-Li Xu,  and Qi-Dong You
73593-73606
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Chicken GHR natural antisense transcript regulates GHR mRNA in LMH cells

Chicken GHR natural antisense transcript regulates GHR mRNA in LMH cells

https://doi.org/10.18632/oncotarget.12437

Li Zhang, Shudai Lin, Lilong An, Jinge Ma, Fengfang Qiu, Rumin Jia, Qinghua Nie, Dexiang Zhang, Qingbin Luo, Ting Li, Zhang Wang,  and Xiquan Zhang
73607-73617
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Anti-EGFR monoclonal antibodies and EGFR tyrosine kinase inhibitors as combination therapy for triple-negative breast cancer

Anti-EGFR monoclonal antibodies and EGFR tyrosine kinase inhibitors as combination therapy for triple-negative breast cancer

https://doi.org/10.18632/oncotarget.12037

Abderrahim El Guerrab, Mahchid Bamdad, Fabrice Kwiatkowski, Yves-Jean Bignon, Frédérique Penault-Llorca,  and Corinne Aubel
73618-73637
Abstract  |  PDF  |  HTML  |  Order a Reprint

Decreased expression of IDH1-R132H correlates with poor survival in gastrointestinal cancer

Decreased expression of IDH1-R132H correlates with poor survival in gastrointestinal cancer

https://doi.org/10.18632/oncotarget.12039

Jieying Li, Jianfei Huang, Fang Huang, Qing Jin, Huijun Zhu, Xudong Wang,  and Meng Chen
73638-73650
Abstract  |  PDF  |  HTML  |  Order a Reprint

Locked nucleic acid-inhibitor of miR-205 decreases endometrial cancer cells proliferation in vitro and in vivo

Locked nucleic acid-inhibitor of miR-205 decreases endometrial cancer cells proliferation in vitro and in vivo

https://doi.org/10.18632/oncotarget.12043

Anna Torres, Joanna Kozak, Agnieszka Korolczuk, Dominika Rycak, Paulina Wdowiak, Ryszard Maciejewski,  and Kamil Torres
73651-73663
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Uncovering synthetic lethal interactions for therapeutic targets and predictive markers in lung adenocarcinoma

Uncovering synthetic lethal interactions for therapeutic targets and predictive markers in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.12046

Jan-Gowth Chang, Chia-Cheng Chen, Yi-Ying Wu, Ting-Fang Che, Yi-Syuan Huang, Kun-Tu Yeh, Grace S. Shieh,  and Pan-Chyr Yang
73664-73680
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Asn-Gly-Arg-modified polydopamine-coated nanoparticles for dual-targeting therapy of brain glioma in rats

Asn-Gly-Arg-modified polydopamine-coated nanoparticles for dual-targeting therapy of brain glioma in rats

https://doi.org/10.18632/oncotarget.12047

Jiangang Hu, Xiang Zhang, Zuhuang Wen, Ying Tan, Ning Huang, Si Cheng, Huzhi Zheng,  and Yuan Cheng
73681-73696
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Second-generation proteasome inhibitor carfilzomib enhances doxorubicin-induced cytotoxicity and apoptosis in breast cancer cells

Second-generation proteasome inhibitor carfilzomib enhances doxorubicin-induced cytotoxicity and apoptosis in breast cancer cells

https://doi.org/10.18632/oncotarget.12048

Yonghua Shi, Yang Yu, Zhenyu Wang, Hao Wang, Shayahati Bieerkehazhi, Yanling Zhao, Lale Suzuk,  and Hong Zhang
73697-73710
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Lipopolysaccharide increases the release of VEGF-C that enhances cell motility and promotes lymphangiogenesis and lymphatic metastasis through the TLR4- NF-κB/JNK pathways in colorectal cancer

Lipopolysaccharide increases the release of VEGF-C that enhances cell motility and promotes lymphangiogenesis and lymphatic metastasis through the TLR4- NF-κB/JNK pathways in colorectal cancer

https://doi.org/10.18632/oncotarget.12449

Guangwei Zhu, Qiang Huang, Yongjian Huang, Wei Zheng, Jin Hua, Shugang Yang, Jinfu Zhuang, Jinzhou Wang,  and Jianxin Ye
73711-73724
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Role of BCL9L in transforming growth factor-β (TGF-β)-induced epithelial-to-mesenchymal-transition (EMT) and metastasis of pancreatic cancer

Role of BCL9L in transforming growth factor-β (TGF-β)-induced epithelial-to-mesenchymal-transition (EMT) and metastasis of pancreatic cancer

https://doi.org/10.18632/oncotarget.12455

Giuseppina Sannino, Nicole Armbruster, Mona Bodenhöfer, Ursula Haerle, Diana Behrens, Malte Buchholz, Ulrich Rothbauer, Bence Sipos,  and Christian Schmees
73725-73738
Abstract  |  PDF  |  HTML  |  Order a Reprint

The other face of miR-17-92a cluster, exhibiting tumor suppressor effects in prostate cancer

The other face of miR-17-92a cluster, exhibiting tumor suppressor effects in prostate cancer

https://doi.org/10.18632/oncotarget.12061

Richard Ottman, Jenna Levy, Williams E. Grizzle,  and Ratna Chakrabarti
73739-73753
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Bone morphogenetic protein-9 is a potent growth inhibitor of hepatocellular carcinoma and reduces the liver cancer stem cells population

Bone morphogenetic protein-9 is a potent growth inhibitor of hepatocellular carcinoma and reduces the liver cancer stem cells population

https://doi.org/10.18632/oncotarget.12062

Jae Woo Jung, So-Mi Yoon, Subin Kim, Yun-Hui Jeon, Byung-Hak Yoon, Su-Geun Yang, Min Kyoung Kim, Senyon Choe,  and Mario Meng-Chiang Kuo
73754-73768
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia

Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.12063

Farzaneh Ghazavi, Barbara De Moerloose, Wouter Van Loocke, Annelynn Wallaert, Hetty H. Helsmoortel, Alina Ferster, Marleen Bakkus, Geneviève Plat, Eric Delabesse, Anne Uyttebroeck, Filip Van Nieuwerburgh, Dieter Deforce, Nadine Van Roy, Frank Speleman, Yves Benoit, Tim Lammens,  and Pieter Van Vlierberghe
73769-73780
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TERT rs2853676 polymorphisms correlate with glioma prognosis in Chinese population

TERT rs2853676 polymorphisms correlate with glioma prognosis in Chinese population

https://doi.org/10.18632/oncotarget.12064

Xue He, Yahui Wei, Zhengshuai Chen, Xikai Zhu, Lifeng Ma, Ning Zhang, Yuan Zhang, Longli Kang, Dongya Yuan, Zongyong Zhang,  and Tianbo Jin
73781-73791
Abstract  |  PDF  |  HTML  |  Order a Reprint

A dosimetric and treatment efficiency evaluation of stereotactic body radiation therapy for peripheral lung cancer using flattening filter free beams

A dosimetric and treatment efficiency evaluation of stereotactic body radiation therapy for peripheral lung cancer using flattening filter free beams

https://doi.org/10.18632/oncotarget.12071

Ji-Yong Zhang, Jia-Yang Lu, Li-Li Wu, Dan-Li Hong, Chang-chun Ma, Xun Peng,  and Zhi-Xiong Lin
73792-73799
Abstract  |  PDF  |  HTML  |  Order a Reprint

Epithelial splicing regulatory protein 1 and 2 paralogues correlate with splice signatures and favorable outcome in human colorectal cancer

Epithelial splicing regulatory protein 1 and 2 paralogues correlate with splice signatures and favorable outcome in human colorectal cancer

https://doi.org/10.18632/oncotarget.12070

Abigail J. Deloria, Doris Höflmayer, Philip Kienzl, Justyna Łopatecka, Sandra Sampl, Martin Klimpfinger, Tamara Braunschmid, Fabienne Bastian, Lingeng Lu, Brigitte Marian, Stefan Stättner,  and Klaus Holzmann
73800-73816
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SHP2 phosphatase as a novel therapeutic target for melanoma treatment

SHP2 phosphatase as a novel therapeutic target for melanoma treatment

https://doi.org/10.18632/oncotarget.12074

Ruo-Yu Zhang, Zhi-Hong Yu, Lifan Zeng, Sheng Zhang, Yunpeng Bai, Jinmin Miao, Lan Chen, Jingwu Xie,  and Zhong-Yin Zhang
73817-73829
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tetraspecific scFv construct provides NK cell mediated ADCC and self-sustaining stimuli via insertion of IL-15 as a cross-linker

Tetraspecific scFv construct provides NK cell mediated ADCC and self-sustaining stimuli via insertion of IL-15 as a cross-linker

https://doi.org/10.18632/oncotarget.12073

Joerg U. Schmohl, Martin Felices, Deborah Todhunter, Elizabeth Taras, Jeffrey S. Miller,  and Daniel A. Vallera
73830-73844
Abstract  |  PDF  |  HTML  |  Order a Reprint

CoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network

CoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network

https://doi.org/10.18632/oncotarget.12075

Elana J. Fertig, Hiroyuki Ozawa, Manjusha Thakar, Jason D. Howard, Luciane T. Kagohara, Gabriel Krigsfeld, Ruchira S. Ranaweera, Robert M. Hughes, Jimena Perez, Siân Jones, Alexander V. Favorov, Jacob Carey, Genevieve Stein-O’Brien, Daria A. Gaykalova, Daria A. Gaykalova, Michael F. Ochs,  and Christine H. Chung
73845-73864
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Novel lymph node ratio predicts prognosis of colorectal cancer patients after radical surgery when tumor deposits are counted as positive lymph nodes: a retrospective multicenter study

Novel lymph node ratio predicts prognosis of colorectal cancer patients after radical surgery when tumor deposits are counted as positive lymph nodes: a retrospective multicenter study

https://doi.org/10.18632/oncotarget.12076

Jin Yang, Shasha Xing, Jun Li, Shengke Yang, Junjie Hu, Hao Liu, Feng Du, Jie Yin, Sai Liu, Ci Li, Jiatian Yuan,  and Bo Lv
73865-73875
Abstract  |  PDF  |  HTML  |  Order a Reprint

Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients

Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients

https://doi.org/10.18632/oncotarget.12510

Evert van den Broek, Oscar Krijgsman, Daoud Sie, Marianne Tijssen, Sandra Mongera, Mark A. van de Wiel, Eric J. Th. Belt, Sjoerd H. den Uil, Herman Bril, Hein B.A.C. Stockmann, Bauke Ylstra, Beatriz Carvalho, Gerrit A. Meijer,  and Remond J.A. Fijneman
73876-73887
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-28-5p acts as a tumor suppressor in renal cell carcinoma for multiple antitumor effects by targeting RAP1B

miR-28-5p acts as a tumor suppressor in renal cell carcinoma for multiple antitumor effects by targeting RAP1B

https://doi.org/10.18632/oncotarget.12516

Cheng Wang, Caiyun Wu, Qi Yang, Meng Ding, Jinsha Zhong, Chen-Yu Zhang, Jingping Ge, Junjun Wang,  and Chunni Zhang
73888-73902
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The impact of neuronal Notch-1/JNK pathway on intracerebral hemorrhage-induced neuronal injury of rat model

The impact of neuronal Notch-1/JNK pathway on intracerebral hemorrhage-induced neuronal injury of rat model

https://doi.org/10.18632/oncotarget.12094

Maohua Chen, Jun Sun, Chuan Lu, Xiandong Chen, Huajun Ba, Qun Lin, Jianyong Cai,  and Junxia Dai
73903-73911
Abstract  |  PDF  |  HTML  |  Order a Reprint

Antibody-based PET of uPA/uPAR signaling with broad applicability for cancer imaging

Antibody-based PET of uPA/uPAR signaling with broad applicability for cancer imaging

https://doi.org/10.18632/oncotarget.12528

Dongzhi Yang, Gregory W. Severin, Casey A. Dougherty, Rachel Lombardi, Daiqin Chen, Marcian E. Van Dort, Todd E. Barnhart, Brian D. Ross, Andrew P. Mazar,  and Hao Hong
73912-73924
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Transfer of functional microRNAs between glioblastoma and microvascular endothelial cells through gap junctions

Transfer of functional microRNAs between glioblastoma and microvascular endothelial cells through gap junctions

https://doi.org/10.18632/oncotarget.12136

Dominique Thuringer, Jonathan Boucher, Gaetan Jego, Nicolas Pernet, Laurent Cronier, Arlette Hammann, Eric Solary,  and Carmen Garrido
73925-73934
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A PRISMA-compliant meta-analysis of MDM4 genetic variants and cancer susceptibility

A PRISMA-compliant meta-analysis of MDM4 genetic variants and cancer susceptibility

https://doi.org/10.18632/oncotarget.12558

Yajing Zhai, Zhijun Dai, Hairong He, Fan Gao, Lihong Yang, Yalin Dong,  and Jun Lu
73935-73944
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A comprehensive meta-analysis of genetic associations between five key SNPs and colorectal cancer risk

A comprehensive meta-analysis of genetic associations between five key SNPs and colorectal cancer risk

https://doi.org/10.18632/oncotarget.12154

Yi Hong, Guoying Wu, Wei Li, Dahai Liu,  and Kan He
73945-73959
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells

The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells

https://doi.org/10.18632/oncotarget.12170

Yannick Willemen, Johan M.J. Van den Bergh, Sarah M. Bonte, Sébastien Anguille, Carlo Heirman, Barbara M.H. Stein, Herman Goossens, Tessa Kerre, Kris Thielemans, Marc Peeters, Viggo F.I. Van Tendeloo, Evelien L.J. Smits,  and Zwi N. Berneman
73960-73970
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of a five B cell-associated gene prognostic and predictive signature for advanced glioma patients harboring immunosuppressive subtype preference

Identification of a five B cell-associated gene prognostic and predictive signature for advanced glioma patients harboring immunosuppressive subtype preference

https://doi.org/10.18632/oncotarget.12605

Chuanbao Zhang, Jiye Li, Haoyuan Wang,  and Sonya Wei Song
73971-73983
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circulating vascular endothelial growth factor (VEGF) as predictive factor of progression-free survival in patients with advanced chordoma receiving sorafenib: an analysis from a phase II trial of the french sarcoma group (GSF/GETO)

Circulating vascular endothelial growth factor (VEGF) as predictive factor of progression-free survival in patients with advanced chordoma receiving sorafenib: an analysis from a phase II trial of the french sarcoma group (GSF/GETO)

https://doi.org/10.18632/oncotarget.12172

Loic Lebellec, François Bertucci, Emmanuelle Tresch-Bruneel, Emmanuelle Bompas, Yves Toiron, Luc Camoin, Olivier Mir, Valerie Laurence, Stephanie Clisant, Emilie Decoupigny, Jean-Yves Blay, Anthony Goncalves,  and Nicolas Penel
73984-73994
Abstract  |  PDF  |  HTML  |  Order a Reprint

Generation of affibody molecules specific for HPV16 E7 recognition

Generation of affibody molecules specific for HPV16 E7 recognition

https://doi.org/10.18632/oncotarget.12174

Xiangyang Xue, Bingbing Wang, Wangqi Du, Chanqiong Zhang, Yiling Song, Yiqi Cai, Danwei Cen, Ledan Wang, Yirong Xiong, Pengfei Jiang, Shanli Zhu, Kong-Nan Zhao,  and Lifang Zhang
73995-74005
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cystic brain metastasis is associated with poor prognosis in patients with advanced breast cancer

Cystic brain metastasis is associated with poor prognosis in patients with advanced breast cancer

https://doi.org/10.18632/oncotarget.12176

Bing Sun, Zhou Huang, Shikai Wu, Lijuan Ding, Ge Shen, Lei Cha, Junliang Wang,  and Santai Song
74006-74014
Abstract  |  PDF  |  HTML  |  Order a Reprint

FGF4 induces epithelial-mesenchymal transition by inducing store-operated calcium entry in lung adenocarcinoma

FGF4 induces epithelial-mesenchymal transition by inducing store-operated calcium entry in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.12187

Lisha Qi, Wangzhao Song, Lingmei Li, Lu Cao, Yue Yu, Chunmin Song, Yalei Wang, Fei Zhang, Yang Li, Bin Zhang,  and Wenfeng Cao
74015-74030
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Classifying lower grade glioma cases according to whole genome gene expression

Classifying lower grade glioma cases according to whole genome gene expression

https://doi.org/10.18632/oncotarget.12188

Baoshi Chen, Tingyu Liang, Pei Yang, Haoyuan Wang, Yanwei Liu, Fan Yang,  and Gan You
74031-74042
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis

Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis

https://doi.org/10.18632/oncotarget.12189

Fernando F. Blanco, Ranjan Preet, Andrea Aguado, Vikalp Vishwakarma, Laura E. Stevens, Alok Vyas, Subhash Padhye, Liang Xu, Scott J. Weir, Shrikant Anant, Nicole Meisner-Kober, Jonathan R. Brody,  and Dan A. Dixon
74043-74058
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-98 acts as a tumor suppressor in hepatocellular carcinoma via targeting SALL4

MicroRNA-98 acts as a tumor suppressor in hepatocellular carcinoma via targeting SALL4

https://doi.org/10.18632/oncotarget.12190

Wuyuan Zhou, Benkui Zou, Lisheng Liu, Kai Cui, Jie Gao, Shuanghu Yuan,  and Ning Cong
74059-74073
Abstract  |  PDF  |  HTML  |  Order a Reprint

Axillary and internal mammary sentinel lymph node biopsy in breast cancer after neoadjuvant chemotherapy

Axillary and internal mammary sentinel lymph node biopsy in breast cancer after neoadjuvant chemotherapy

https://doi.org/10.18632/oncotarget.12615

Xiao-Shan Cao, Hui-Juan Li, Bin-Bin Cong, Xiao Sun, Peng-Fei Qiu, Yan-Bing Liu, Chun-Jian Wang,  and Yong-Sheng Wang
74074-74081
Abstract  |  PDF  |  HTML  |  Order a Reprint

Variable but consistent pattern of Meningioma 1 gene (MN1) expression in different genetic subsets of acute myelogenous leukaemia and its potential use as a marker for minimal residual disease detection

Variable but consistent pattern of Meningioma 1 gene (MN1) expression in different genetic subsets of acute myelogenous leukaemia and its potential use as a marker for minimal residual disease detection

https://doi.org/10.18632/oncotarget.12269

Sonia Carturan, Jessica Petiti, Valentina Rosso, Chiara Calabrese, Elisabetta Signorino, Giada Bot-Sartor, Paolo Nicoli, Daniela Gallo, Enrico Bracco, Alessandro Morotti, Cristina Panuzzo, Enrico Gottardi, Francesco Frassoni, Giuseppe Saglio,  and Daniela Cilloni
74082-74096
Abstract  |  PDF  |  HTML  |  Order a Reprint

Somatic alterations of targetable oncogenes are frequently observed in BRCA1/2 mutation negative male breast cancers

Somatic alterations of targetable oncogenes are frequently observed in BRCA1/2 mutation negative male breast cancers

https://doi.org/10.18632/oncotarget.12272

Piera Rizzolo, Anna Sara Navazio, Valentina Silvestri, Virginia Valentini, Veronica Zelli, Ines Zanna, Giovanna Masala, Simonetta Bianchi, Marco Scarnò, Stefania Tommasi, Domenico Palli,  and Laura Ottini
74097-74106
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Immune adjuvant effect of a Toxoplasma gondii profilin-like protein in autologous whole-tumor-cell vaccination in mice

Immune adjuvant effect of a Toxoplasma gondii profilin-like protein in autologous whole-tumor-cell vaccination in mice

https://doi.org/10.18632/oncotarget.12316

Kyoung-Ho Pyo, You-Won Lee, Sun Min Lim,  and Eun-Hee Shin
74107-74119
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Exploring timing activation of functional pathway based on differential co-expression analysis in preimplantation embryogenesis

Exploring timing activation of functional pathway based on differential co-expression analysis in preimplantation embryogenesis

https://doi.org/10.18632/oncotarget.12339

Yongchun Zuo, Guanghua Su, Shanshan Wang, Lei Yang, Mingzhi Liao, Zhuying Wei, Chunling Bai,  and Guangpeng Li
74120-74131
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mitochondrial dysfunction enhances cisplatin resistance in human gastric cancer cells via the ROS-activated GCN2-eIF2α-ATF4-xCT pathway

Mitochondrial dysfunction enhances cisplatin resistance in human gastric cancer cells via the ROS-activated GCN2-eIF2α-ATF4-xCT pathway

https://doi.org/10.18632/oncotarget.12356

Sheng-Fan Wang, Meng-Shian Chen, Yueh-Ching Chou, Yune-Fang Ueng, Pen-Hui Yin, Tien-Shun Yeh,  and Hsin-Chen Lee
74132-74151
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cytomorphological characteristics of glassy cell carcinoma of the uterine cervix: histopathological correlation and human papillomavirus genotyping

Cytomorphological characteristics of glassy cell carcinoma of the uterine cervix: histopathological correlation and human papillomavirus genotyping

https://doi.org/10.18632/oncotarget.12361

Yoon Yang Jung, Ji Hae Nahm,  and Hyun-Soo Kim
74152-74161
Abstract  |  PDF  |  HTML  |  Order a Reprint

Advanced lung adenocarcinomas with ROS1-rearrangement frequently show hepatoid cell

Advanced lung adenocarcinomas with ROS1-rearrangement frequently show hepatoid cell

https://doi.org/10.18632/oncotarget.12364

Jing Zhao, Jing Zheng, Mei Kong, Jianya Zhou, Wei Ding,  and Jianying Zhou
74162-74170
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Engineering of double recombinant vaccinia virus with enhanced oncolytic potential for solid tumor virotherapy

Engineering of double recombinant vaccinia virus with enhanced oncolytic potential for solid tumor virotherapy

https://doi.org/10.18632/oncotarget.12367

Galina Kochneva, Galina Sivolobova, Anastasiya Tkacheva, Antonina Grazhdantseva, Olga Troitskaya, Anna Nushtaeva, Anastasiya Tkachenko, Elena Kuligina, Vladimir Richter,  and Olga Koval
74171-74188
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prostate-specific membrane antigen (PSMA) assembles a macromolecular complex regulating growth and survival of prostate cancer cells “in vitro” and correlating with progression “in vivo

Prostate-specific membrane antigen (PSMA) assembles a macromolecular complex regulating growth and survival of prostate cancer cells “in vitro” and correlating with progression “in vivo

https://doi.org/10.18632/oncotarget.12404

Maria Elisa Perico, Silvia Grasso, Matteo Brunelli, Guido Martignoni, Enrico Munari, Enrico Moiso, Giulio Fracasso, Tiziana Cestari, Hassan Y. Naim, Vincenzo Bronte, Marco Colombatti,  and Dunia Ramarli
74189-74202
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Low pH impairs complement-dependent cytotoxicity against IgG-coated target cells

Low pH impairs complement-dependent cytotoxicity against IgG-coated target cells

https://doi.org/10.18632/oncotarget.12412

Ezequiel Dantas, Fernando Erra Díaz, Pehuén Pereyra Gerber, Antonela Merlotti, Augusto Varese, Matías Ostrowski, Juan Sabatté,  and Jorge Geffner
74203-74216
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-126 affects rheumatoid arthritis synovial fibroblast proliferation and apoptosis by targeting PIK3R2 and regulating PI3K-AKT signal pathway

MicroRNA-126 affects rheumatoid arthritis synovial fibroblast proliferation and apoptosis by targeting PIK3R2 and regulating PI3K-AKT signal pathway

https://doi.org/10.18632/oncotarget.12487

Yuan Qu, Jing Wu, Jia-Xin Deng, Yu-Ping Zhang, Wan-Yi Liang, Zhen-Lan Jiang, Qing-Hong Yu,  and Juan Li
74217-74226
Abstract  |  PDF  |  HTML  |  Order a Reprint

Germline mutations in Japanese familial pancreatic cancer patients

Germline mutations in Japanese familial pancreatic cancer patients

https://doi.org/10.18632/oncotarget.12490

Erina Takai, Shinichi Yachida, Kyoko Shimizu, Junji Furuse, Emi Kubo, Akihiro Ohmoto, Masami Suzuki, Ralph H. Hruban, Takuji Okusaka, Chigusa Morizane,  and Toru Furukawa
74227-74235
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression and potential roles of NRIP1 in psoriasis

Overexpression and potential roles of NRIP1 in psoriasis

https://doi.org/10.18632/oncotarget.12371

Chao Luan, Xu Chen, Yu Hu, Zhimin Hao, Jared M. Osland, Xundi Chen, Skyler D. Gerber, Min Chen, Heng Gu,  and Rong Yuan
74236-74246
Abstract  |  PDF  |  HTML  |  Order a Reprint

Endotoxin promotes neutrophil hierarchical chemotaxis via the p38-membrane receptor pathway

Endotoxin promotes neutrophil hierarchical chemotaxis via the p38-membrane receptor pathway

https://doi.org/10.18632/oncotarget.12093

Xu Wang, Weiting Qin, Yisen Zhang, Huafeng Zhang,  and Bingwei Sun
74247-74258
Abstract  |  PDF  |  HTML  |  Order a Reprint

A next-generation bifunctional photosensitizer with improved water-solubility for photodynamic therapy and diagnosis

A next-generation bifunctional photosensitizer with improved water-solubility for photodynamic therapy and diagnosis

https://doi.org/10.18632/oncotarget.12366

Hirotada Nishie, Hiromi Kataoka, Shigenobu Yano, Jun-ichi Kikuchi, Noriyuki Hayashi, Atsushi Narumi, Akihiro Nomoto, Eiji Kubota,  and Takashi Joh
74259-74268
Abstract  |  PDF  |  HTML  |  Order a Reprint

Proteomic identification of the lactate dehydrogenase A in a radioresistant prostate cancer xenograft mouse model for improving radiotherapy

Proteomic identification of the lactate dehydrogenase A in a radioresistant prostate cancer xenograft mouse model for improving radiotherapy

https://doi.org/10.18632/oncotarget.12368

Jingli Hao, Peter Graham, Lei Chang, Jie Ni, Valerie Wasinger, Julia Beretov, Junli Deng, Wei Duan, Joseph Bucci, David Malouf, David Gillatt,  and Yong Li
74269-74285
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Quantitative assessment of CD44 genetic variants and cancer susceptibility in Asians: a meta-analysis

Quantitative assessment of CD44 genetic variants and cancer susceptibility in Asians: a meta-analysis

https://doi.org/10.18632/oncotarget.10951

Vishal Chandra, Yun-Mi Lee, Usha Gupta, Balraj Mittal, Jong Joo Kim,  and Rajani Rai
74286-74302
Abstract  |  PDF  |  HTML  |  Order a Reprint

Role of transarterial chemoembolization in relation with sorafenib for patients with advanced hepatocellular carcinoma

Role of transarterial chemoembolization in relation with sorafenib for patients with advanced hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.11030

Yeonjung Ha, Danbi Lee, Ju Hyun Shim, Young-Suk Lim, Han Chu Lee, Young-Hwa Chung, Yung Sang Lee, Sook Ryun Park, Min-Hee Ryu, Baek-Yeol Ryoo, Yoon-Koo Kang,  and Kang Mo Kim
74303-74313
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preoperative neutrophil-to-lymphocyte ratio and tumor-related factors to predict lymph node metastasis in patients with pancreatic ductal adenocarcinoma (PDAC)

Preoperative neutrophil-to-lymphocyte ratio and tumor-related factors to predict lymph node metastasis in patients with pancreatic ductal adenocarcinoma (PDAC)

https://doi.org/10.18632/oncotarget.11031

Lianyuan Tao, Lingfu Zhang, Ying Peng, Ming Tao, Gang Li, Dianrong Xiu, Chunhui Yuan, Chaolai Ma,  and Bin Jiang
74314-74324
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LncRNAs act as prognostic and diagnostic biomarkers in renal cell carcinoma: a systematic review and meta-analysis

LncRNAs act as prognostic and diagnostic biomarkers in renal cell carcinoma: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.11101

Jianwen Chen, Yalei Chen, Liangyou Gu, Xintao Li, Yu Gao, Xiangjun Lyu, Luyao Chen, Guoxiong Luo, Lei Wang, Yongpeng Xie, Junyao Duan, Cheng Peng,  and Xin Ma
74325-74336
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Lymph node ratio-based staging system as an alternative to the current TNM staging system to assess outcome in adenocarcinoma of the esophagogastric junction after surgical resection

Lymph node ratio-based staging system as an alternative to the current TNM staging system to assess outcome in adenocarcinoma of the esophagogastric junction after surgical resection

https://doi.org/10.18632/oncotarget.11188

Hongdian Zhang, Xiaobin Shang, Chuangui Chen, Yongyin Gao, Xiangming Xiao, Peng Tang, Xiaofeng Duan, Mingjian Yang, Hongjing Jiang,  and Zhentao Yu
74337-74349
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Reviews

The efficacy and potential predictive factors of PD-1/PD-L1 blockades in epithelial carcinoma patients: a systematic review and meta analysis

The efficacy and potential predictive factors of PD-1/PD-L1 blockades in epithelial carcinoma patients: a systematic review and meta analysis

https://doi.org/10.18632/oncotarget.11291

Yufan Yang, ZhaoFei Pang, Nan Ding, Wei Dong, Wei Ma, Yun Li, Jiajun Du,  and Qi Liu
74350-74361
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Prognostic and predictive value of EGFR in head and neck squamous cell carcinoma

Prognostic and predictive value of EGFR in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.11413

Paolo Bossi, Carlo Resteghini, Nicholas Paielli, Lisa Licitra, Silvana Pilotti,  and Federica Perrone
74362-74379
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Discovery and clinical introduction of first-in-class imipridone ONC201

Discovery and clinical introduction of first-in-class imipridone ONC201

https://doi.org/10.18632/oncotarget.11814

Joshua E. Allen, C. Leah B. Kline, Varun V. Prabhu, Jessica Wagner, Jo Ishizawa, Neel Madhukar, Avital Lev, Marie Baumeister, Lanlan Zhou, Amriti Lulla, Martin Stogniew, Lee Schalop, Cyril Benes, Howard L. Kaufman, Richard S. Pottorf, B. Rao Nallaganchu, Gary L. Olson, Fahd Al-Mulla, Madeleine Duvic, Gen Sheng Wu, David T. Dicker, Mala K. Talekar, Bora Lim, Olivier Elemento, Wolfgang Oster, Joseph Bertino, Keith Flaherty, Michael L. Wang, Gautam Borthakur, Michael Andreeff, Mark Stein,  and Wafik S. El-Deiry
74380-74392
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ISG15 in the tumorigenesis and treatment of cancer: An emerging role in malignancies of the digestive system

ISG15 in the tumorigenesis and treatment of cancer: An emerging role in malignancies of the digestive system

https://doi.org/10.18632/oncotarget.11911

Chaohui Zuo, Xinyi Sheng, Min Ma, Man Xia,  and Linda Ouyang
74393-74409
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Case Reports

Young patient with arterial thrombosis and skin changes as the onset manifestations: POEMS syndrome

Young patient with arterial thrombosis and skin changes as the onset manifestations: POEMS syndrome

https://doi.org/10.18632/oncotarget.12570

Ting-Ting Han, Shuang Zheng, Zeng-Ai Chen, Wei Liu,  and Yao-Min Hu
74410-74414
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