Oncotarget

Vol 7, No 41

October 11, 2016

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About The Cover

The cover for issue 41 of Oncotarget features Figure 7, 'Schematic model summarizing the expression, regulation and function of CD9 in neuroblastoma and indicating the experimental strategies applied' from Fabian, et al.

Table of Contents

Editorial

Drugging the “undruggable” DNA-binding domain of STAT3

Drugging the “undruggable” DNA-binding domain of STAT3

https://doi.org/10.18632/oncotarget.12181

Jian-Ting Zhang,  and Jing-Yuan Liu
66324-66325
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Commentaries

Self-regulation of BAX-induced cell death

Self-regulation of BAX-induced cell death

https://doi.org/10.18632/oncotarget.11948

Denis E. Reyna,  and Evripidis Gavathiotis
66326-66327
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Priority Research Papers

Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21

Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21

https://doi.org/10.18632/oncotarget.11041

Mingfeng Zhang, Zhaoming Wang, Ofure Obazee, Jinping Jia, Erica J. Childs, Jason Hoskins, Gisella Figlioli, Evelina Mocci, Irene Collins, Charles C. Chung, Christopher Hautman, Alan A. Arslan, Laura Beane-Freeman, Paige M. Bracci, Julie Buring, Eric J. Duell, Steven Gallinger, Graham G. Giles, Gary E. Goodman, Phyllis J. Goodman, Aruna Kamineni, Laurence N. Kolonel, Matthew H. Kulke, Núria Malats, Sara H. Olson, Howard D. Sesso, Kala Visvanathan, Emily White, Wei Zheng, Christian C. Abnet, Demetrius Albanes, Gabriella Andreotti, Lauren Brais, H. Bas Bueno-de-Mesquita, Daniela Basso, Sonja I. Berndt, Marie-Christine Boutron-Ruault, Maarten F. Bijlsma, Hermann Brenner, Laurie Burdette, Daniele Campa, Neil E. Caporaso, Gabriele Capurso, Giulia Martina Cavestro, Michelle Cotterchio, Eithne Costello, Joanne Elena, Ugo Boggi, J. Michael Gaziano, Maria Gazouli, Edward L. Giovannucci, Michael Goggins, Myron Gross, Christopher A. Haiman, Manal Hassan, Kathy J. Helzlsouer, Nan Hu, David J. Hunter, Elzbieta Iskierka-Jazdzewska, Mazda Jenab, Rudolf Kaaks, Timothy J. Key, Kay-Tee Khaw, Eric A. Klein, Manolis Kogevinas, Vittorio Krogh, Juozas Kupcinskas, Robert C. Kurtz, Maria T. Landi, Stefano Landi, Loic Le Marchand, Andrea Mambrini, Satu Mannisto, Roger L. Milne, Rachel E. Neale, Ann L. Oberg, Salvatore Panico, Alpa V. Patel, Petra H. M. Peeters, Ulrike Peters, Raffaele Pezzilli, Miquel Porta, Mark Purdue, J. Ramón Quiros, Elio Riboli, Nathaniel Rothman, Aldo Scarpa, Ghislaine Scelo, Xiao-Ou Shu, Debra T. Silverman, Pavel Soucek, Oliver Strobel, Malin Sund, Ewa Małecka-Panas, Philip R. Taylor, Francesca Tavano, Ruth C. Travis, Mark Thornquist, , Geoffrey S. Tobias, Dimitrios Trichopoulos, Yogesh Vashist, Pavel Vodicka, Jean Wactawski-Wende, Nicolas Wentzensen, Herbert Yu, Anne Zeleniuch-Jacquotte, Charles Kooperberg, Harvey A. Risch, Eric J. Jacobs, Donghui Li, Charles Fuchs, Robert Hoover, Patricia Hartge, Stephen J. Chanock, Gloria M. Petersen, Rachael S. Stolzenberg-Solomon, Brian M. Wolpin, Peter Kraft, Alison P. Klein, Federico Canzian,  and Laufey T. Amundadottir
66328-66343
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MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma

MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma

https://doi.org/10.18632/oncotarget.11662

Johannes Fabian, Desirée Opitz, Kristina Althoff, Marco Lodrini, Barbara Hero, Ruth Volland, Anneleen Beckers, Katleen de Preter, Anneleen Decock, Nitin Patil, Mohammed Abba, Annette Kopp-Schneider, Kathy Astrahantseff, Jasmin Wünschel, Sebastian Pfeil, Maria Ercu, Annette Künkele, Jamie Hu, Theresa Thole, Leonille Schweizer, Gunhild Mechtersheimer, Daniel Carter, Belamy B. Cheung, Odilia Popanda, Andreas von Deimling, Jan Koster, Rogier Versteeg, Manfred Schwab, Glenn M. Marshall, Frank Speleman, Ulrike Erb, Margot Zoeller, Heike Allgayer, Thorsten Simon, Matthias Fischer, Andreas E. Kulozik, Angelika Eggert, Olaf Witt, Johannes H. Schulte,  and Hedwig E. Deubzer
66344-66359
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Noncanonical SQSTM1/p62-Nrf2 pathway activation mediates proteasome inhibitor resistance in multiple myeloma cells via redox, metabolic and translational reprogramming

Noncanonical SQSTM1/p62-Nrf2 pathway activation mediates proteasome inhibitor resistance in multiple myeloma cells via redox, metabolic and translational reprogramming

https://doi.org/10.18632/oncotarget.11960

Irene Riz, Teresa S. Hawley, Jeffrey W. Marsal,  and Robert G. Hawley
66360-66385
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PML/RARa inhibits PTEN expression in hematopoietic cells by competing with PU.1 transcriptional activity

PML/RARa inhibits PTEN expression in hematopoietic cells by competing with PU.1 transcriptional activity

https://doi.org/10.18632/oncotarget.11964

Nélida Inés Noguera, Maria Liliana Piredda, Riccardo Taulli, Gianfranco Catalano, Giulia Angelini, Girish Gaur, Clara Nervi, Maria Teresa Voso, Andrea Lunardi, Pier Paolo Pandolfi,  and Francesco Lo-Coco
66386-66397
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Smyd2 is a Myc-regulated gene critical for MLL-AF9 induced leukemogenesis

Smyd2 is a Myc-regulated gene critical for MLL-AF9 induced leukemogenesis

https://doi.org/10.18632/oncotarget.12012

Sevgi Bagislar, Arianna Sabò, Theresia R. Kress, Mirko Doni, Paola Nicoli, Stefano Campaner,  and Bruno Amati
66398-66415
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Research Papers: Gerotarget (Focus on Aging)

Sex-specific autophagy modulation in osteoblastic lineage: a critical function to counteract bone loss in female

Sex-specific autophagy modulation in osteoblastic lineage: a critical function to counteract bone loss in female

https://doi.org/10.18632/oncotarget.12013

Olivier Camuzard, Sabine Santucci-Darmanin, Véronique Breuil, Chantal Cros, Tatiana Gritsaenko, Sophie Pagnotta, Laurence Cailleteau, Séverine Battaglia, Patricia Panaïa-Ferrari, Dominique Heymann, Georges F. Carle,  and Valérie Pierrefite-Carle
66416-66428
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NOX4 downregulation leads to senescence of human vascular smooth muscle cells

NOX4 downregulation leads to senescence of human vascular smooth muscle cells

https://doi.org/10.18632/oncotarget.12079

Dorota Przybylska, Dorota Janiszewska, Aleksandra Goździk, Anna Bielak-Zmijewska, Piotr Sunderland, Ewa Sikora,  and Grażyna Mosieniak
66429-66443
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β-Hydroxybutyrate suppresses inflammasome formation by ameliorating endoplasmic reticulum stress via AMPK activation

β-Hydroxybutyrate suppresses inflammasome formation by ameliorating endoplasmic reticulum stress via AMPK activation

https://doi.org/10.18632/oncotarget.12119

Ha Ram Bae, Dae Hyun Kim, Min Hi Park, Bonggi Lee, Min Jo Kim, Eun Kyeong Lee, Ki Wung Chung, Seong Min Kim, Dong Soon Im,  and Hae Young Chung
66444-66454
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Research Papers: Pathology

CircRNA expression pattern and circRNA-miRNA-mRNA network in the pathogenesis of nonalcoholic steatohepatitis

CircRNA expression pattern and circRNA-miRNA-mRNA network in the pathogenesis of nonalcoholic steatohepatitis

https://doi.org/10.18632/oncotarget.12186

Xi Jin, Chun-yan Feng, Zun Xiang, Yi-peng Chen,  and You-ming Li
66455-66467
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Research Papers: Immunology

Suppression of human metapneumovirus (HMPV) infection by the innate sensing gene CEACAM1

Suppression of human metapneumovirus (HMPV) infection by the innate sensing gene CEACAM1

https://doi.org/10.18632/oncotarget.11979

Mohammad Diab, Alon Vitenshtein, Yaron Drori, Rachel Yamin, Oded Danziger, Rachel Zamostiano, Michal Mandelboim, Eran Bacharach,  and Ofer Mandelboim
66468-66479
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Research Papers

Bisphosphonates enhance EGFR-TKIs efficacy in advanced NSCLC patients with EGFR activating mutation: A retrospective study

Bisphosphonates enhance EGFR-TKIs efficacy in advanced NSCLC patients with EGFR activating mutation: A retrospective study

https://doi.org/10.18632/oncotarget.5515

Chu-ying Huang, Li Wang, Cheng-jun Feng, Ping Yu, Hong-xiao Cai, Wen-xiu Yao, Yong Xu, Xiao-ke Liu, Wen-jiang Zhu, Yan Wang, Jin Zhou, You Lu,  and Yong-sheng Wang
66480-66490
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metabolic flux-driven sialylation alters internalization, recycling, and drug sensitivity of the epidermal growth factor receptor (EGFR) in SW1990 pancreatic cancer cells

Metabolic flux-driven sialylation alters internalization, recycling, and drug sensitivity of the epidermal growth factor receptor (EGFR) in SW1990 pancreatic cancer cells

https://doi.org/10.18632/oncotarget.11582

Mohit P. Mathew, Elaine Tan, Christopher T. Saeui, Patawut Bovonratwet, Samuel Sklar, Rahul Bhattacharya,  and Kevin J. Yarema
66491-66511
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Rottlerin exerts its anti-tumor activity through inhibition of Skp2 in breast cancer cells

Rottlerin exerts its anti-tumor activity through inhibition of Skp2 in breast cancer cells

https://doi.org/10.18632/oncotarget.11614

Xuyuan Yin, Yu Zhang, Jingna Su, Yingying Hou, Lixia Wang, Xiantao Ye, Zhe Zhao, Xiuxia Zhou, Yali Li,  and Zhiwei Wang
66512-66524
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Double mutant P53 (N340Q/L344R) promotes hepatocarcinogenesis through upregulation of Pim1 mediated by PKM2 and LncRNA CUDR

Double mutant P53 (N340Q/L344R) promotes hepatocarcinogenesis through upregulation of Pim1 mediated by PKM2 and LncRNA CUDR

https://doi.org/10.18632/oncotarget.9089

Mengying Wu, Jiahui An, Qidi Zheng, Xiaoru Xin, Zhuojia Lin, Xiaonan Li, Haiyan Li,  and Dongdong Lu
66525-66539
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Inhibiting tryptophan metabolism enhances interferon therapy in kidney cancer

Inhibiting tryptophan metabolism enhances interferon therapy in kidney cancer

https://doi.org/10.18632/oncotarget.11658

Josephine F. Trott, Jeffrey Kim, Omran Abu Aboud, Hiromi Wettersten, Benjamin Stewart, Grace Berryhill, Francisco Uzal, Russell C. Hovey, Ching-Hsien Chen, Katie Anderson, Ashley Graef, Aaron L Sarver, Jaime F. Modiano,  and Robert H. Weiss
66540-66557
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Perfluorooctanoic acid induces human Ishikawa endometrial cancer cell migration and invasion through activation of ERK/mTOR signaling

Perfluorooctanoic acid induces human Ishikawa endometrial cancer cell migration and invasion through activation of ERK/mTOR signaling

https://doi.org/10.18632/oncotarget.11684

Zhinan Ma, Xiaoqiu Liu, Fujun Li, Yixong Wang, Yang Xu, Mei Zhang, Xiaoqian Zhang, Xiaoyan Ying,  and Xuesen Zhang
66558-66568
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clustered somatic mutations are frequent in transcription factor binding motifs within proximal promoter regions in melanoma and other cutaneous malignancies

Clustered somatic mutations are frequent in transcription factor binding motifs within proximal promoter regions in melanoma and other cutaneous malignancies

https://doi.org/10.18632/oncotarget.11892

Andrew J. Colebatch, Leon Di Stefano, Stephen Q. Wong, Ross D. Hannan, Paul M. Waring, Alexander Dobrovic, Grant A. McArthur,  and Anthony T. Papenfuss
66569-66585
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Altered expression of CD226 and CD96 on natural killer cells in patients with pancreatic cancer

Altered expression of CD226 and CD96 on natural killer cells in patients with pancreatic cancer

https://doi.org/10.18632/oncotarget.11953

Yun-Peng Peng, Chun-Hua Xi, Yi Zhu, Ling-Di Yin, Ji-Shu Wei, Jing-Jing Zhang, Xin-Chun Liu, Song Guo, Yue Fu,  and Yi Miao
66586-66594
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Limits and potential of targeted sequencing analysis of liquid biopsy in patients with lung and colon carcinoma

Limits and potential of targeted sequencing analysis of liquid biopsy in patients with lung and colon carcinoma

https://doi.org/10.18632/oncotarget.10704

Anna Maria Rachiglio, Riziero Esposito Abate, Alessandra Sacco, Raffaella Pasquale, Francesca Fenizia, Matilde Lambiase, Alessandro Morabito, Agnese Montanino, Gaetano Rocco, Carmen Romano, Anna Nappi, Rosario Vincenzo Iaffaioli, Fabiana Tatangelo, Gerardo Botti, Fortunato Ciardiello, Monica R. Maiello, Antonella De Luca,  and Nicola Normanno
66595-66605
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Suppressed Helicobacter pylori-associated gastric tumorigenesis in Fat-1 transgenic mice producing endogenous ω-3 polyunsaturated fatty acids

Suppressed Helicobacter pylori-associated gastric tumorigenesis in Fat-1 transgenic mice producing endogenous ω-3 polyunsaturated fatty acids

https://doi.org/10.18632/oncotarget.11261

Young-Min Han, Kyung-Jo Kim, Migyeung Jeong, Jong-Min Park, Eun-Jin Go, Jing X Kang, Sung Pyo Hong,  and Ki Baik Hahm
66606-66622
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Does tumor size improve the accuracy of prognostic prediction in patients with esophageal squamous cell carcinoma after surgical resection?

Does tumor size improve the accuracy of prognostic prediction in patients with esophageal squamous cell carcinoma after surgical resection?

https://doi.org/10.18632/oncotarget.11286

Hongdian Zhang, Peng Tang, Xiaohui Miao, Yongyin Gao, Xiaobin Shang, Lei Gong, Zhao Ma, Mingjian Yang, Hongjing Jiang, Zhongli Zhan, Bin Meng,  and Zhentao Yu
66623-66634
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Distinct role of interleukin-6 and tumor necrosis factor receptor-1 in oval cell- mediated liver regeneration and inflammation-associated hepatocarcinogenesis

Distinct role of interleukin-6 and tumor necrosis factor receptor-1 in oval cell- mediated liver regeneration and inflammation-associated hepatocarcinogenesis

https://doi.org/10.18632/oncotarget.11365

Tong Ji, Gaofeng Li, Jiang Chen, Jie Zhao, Xi Li, Hui Lin, Xiujun Cai,  and Yong Cang
66635-66646
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of ARC decreases the survival of HEI-OC-1 cells after neomycin damage in vitro

Inhibition of ARC decreases the survival of HEI-OC-1 cells after neomycin damage in vitro

https://doi.org/10.18632/oncotarget.11336

Ming Guan, Qiaojun Fang, Zuhong He, Yong Li, Fuping Qian, Xiaoyun Qian, Ling Lu, Xiaoli Zhang, Dingding Liu, Jieyu Qi, Shasha Zhang, Mingliang Tang, Xia Gao,  and Renjie Chai
66647-66659
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression of CHKA contributes to tumor progression and metastasis and predicts poor prognosis in colorectal carcinoma

Overexpression of CHKA contributes to tumor progression and metastasis and predicts poor prognosis in colorectal carcinoma

https://doi.org/10.18632/oncotarget.11433

Liang Hu, Ruo-Yu Wang, Jian Cai, Dan Feng, Guang-Zhen Yang, Qing-Guo Xu, Yan-Xia Zhai, Yu Zhang, Wei-Ping Zhou,  and Qing-Ping Cai
66660-66678
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Common housekeeping proteins are upregulated in colorectal adenocarcinoma and hepatocellular carcinoma, making the total protein a better "housekeeper"

Common housekeeping proteins are upregulated in colorectal adenocarcinoma and hepatocellular carcinoma, making the total protein a better "housekeeper"

https://doi.org/10.18632/oncotarget.11439

Xiaowen Hu, Shujiao Du, Jiekai Yu, Xuhan Yang, Chao Yang, Daizhan Zhou, Qingyu Wang, Shengying Qin, Xiaomei Yan, Lin He, Dongmei Han,  and Chunling Wan
66679-66688
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cheliensisin A (Chel A) induces apoptosis in human bladder cancer cells by promoting PHLPP2 protein degradation

Cheliensisin A (Chel A) induces apoptosis in human bladder cancer cells by promoting PHLPP2 protein degradation

https://doi.org/10.18632/oncotarget.11440

Ruowen Zhang, Xun Che, Jingjie Zhang, Yang Li, Jingxia Li, Xu Deng, Junlan Zhu, Honglei Jin, Qinshi Zhao,  and Chuanshu Huang
66689-66699
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Effect of Helicobacter pylori infection on chronic periodontitis by the change of microecology and inflammation

Effect of Helicobacter pylori infection on chronic periodontitis by the change of microecology and inflammation

https://doi.org/10.18632/oncotarget.11449

Zhekai Hu, Yu Zhang, Zhiyu Li, Yuedi Yu, Wenyan Kang, Yingnan Han, Xiwen Geng, Shaohua Ge,  and Yundong Sun
66700-66712
Abstract  |  PDF  |  HTML  |  Order a Reprint

L-Ferritin targets breast cancer stem cells and delivers therapeutic and imaging agents

L-Ferritin targets breast cancer stem cells and delivers therapeutic and imaging agents

https://doi.org/10.18632/oncotarget.10920

Laura Conti, Stefania Lanzardo, Roberto Ruiu, Marta Cadenazzi, Federica Cavallo, Silvio Aime,  and Simonetta Geninatti Crich
66713-66727
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Coupling of LETM1 up-regulation with oxidative phosphorylation and platelet-derived growth factor receptor signaling via YAP1 transactivation

Coupling of LETM1 up-regulation with oxidative phosphorylation and platelet-derived growth factor receptor signaling via YAP1 transactivation

https://doi.org/10.18632/oncotarget.11456

Jandee Lee, Woo Kyung Lee, Mi-Youn Seol, Seul Gi Lee, Daham Kim, Hyunji Kim, Jongsun Park, Sang Geun Jung, Woong Youn Chung, Eun Jig Lee,  and Young Suk Jo
66728-66739
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ROCK inhibitor reduces Myc-induced apoptosis and mediates immortalization of human keratinocytes

ROCK inhibitor reduces Myc-induced apoptosis and mediates immortalization of human keratinocytes

https://doi.org/10.18632/oncotarget.11458

Aleksandra Dakic, Kyle DiVito, Shuang Fang, Frank Suprynowicz, Anirudh Gaur, Xin Li, Nancy Palechor-Ceron, Vera Simic, Sujata Choudhury, Songtao Yu, Cynthia M. Simbulan-Rosenthal, Dean Rosenthal, Richard Schlegel,  and Xuefeng Liu
66740-66753
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea

Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea

https://doi.org/10.18632/oncotarget.11479

Wenli Ni, Shan Zeng, Wenyan Li, Yan Chen, Shasha Zhang, Mingliang Tang, Shan Sun, Renjie Chai,  and Huawei Li
66754-66768
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

New therapy with ASC-J9® to suppress the prostatitis via altering the cytokine CCL2 signals

New therapy with ASC-J9® to suppress the prostatitis via altering the cytokine CCL2 signals

https://doi.org/10.18632/oncotarget.11484

Shin-Jen Lin, Fu-Ju Chou, Chang-Yi Lin, Hong-Chiang Chang, Shuyuan Yeh,  and Chawnshang Chang
66769-66775
Abstract  |  PDF  |  HTML  |  Order a Reprint

5-ALA fluorescence of cerebral metastases and its impact for the local-in-brain progression

5-ALA fluorescence of cerebral metastases and its impact for the local-in-brain progression

https://doi.org/10.18632/oncotarget.11488

Marcel A. Kamp, Igor Fischer, Julia Bühner, Bernd Turowski, Jan Frederick Cornelius, Hans-Jakob Steiger, Marion Rapp, Philipp J. Slotty,  and Michael Sabel
66776-66789
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Genetic polymorphisms and response to 5-fluorouracil, doxorubicin and cyclophosphamide chemotherapy in breast cancer patients

Genetic polymorphisms and response to 5-fluorouracil, doxorubicin and cyclophosphamide chemotherapy in breast cancer patients

https://doi.org/10.18632/oncotarget.11053

Karolina Tecza, Jolanta Pamula-Pilat, Joanna Lanuszewska,  and Ewa Grzybowska
66790-66808
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JQ1 suppresses tumor growth via PTEN/PI3K/AKT pathway in endometrial cancer

JQ1 suppresses tumor growth via PTEN/PI3K/AKT pathway in endometrial cancer

https://doi.org/10.18632/oncotarget.11631

Haifeng Qiu, Jing Li, Leslie H. Clark, Amanda L. Jackson, Lu Zhang, Hui Guo, Joshua E. Kilgore, Paola A. Gehrig, Chunxiao Zhou,  and Victoria L. Bae-Jump
66809-66821
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of SHCBP1 as a novel downstream target gene of SS18-SSX1 and its functional analysis in progression of synovial sarcoma

Identification of SHCBP1 as a novel downstream target gene of SS18-SSX1 and its functional analysis in progression of synovial sarcoma

https://doi.org/10.18632/oncotarget.11651

Changliang Peng, Hui Zhao, Wei Chen, Yan Song, Xiaoying Wang, Ji Li, Yong Qiao, Dongjin Wu, Shengzhong Ma, Xiuwen Wang,  and Chunzheng Gao
66822-66834
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumor suppressor ARF regulates tissue microenvironment and tumor growth through modulation of macrophage polarization

Tumor suppressor ARF regulates tissue microenvironment and tumor growth through modulation of macrophage polarization

https://doi.org/10.18632/oncotarget.11652

Lidia Jiménez-García, Sandra Herranz, María Angeles Higueras, Alfonso Luque,  and Sonsoles Hortelano
66835-66850
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

eIF4E promotes tumorigenesis and modulates chemosensitivity to cisplatin in esophageal squamous cell carcinoma

eIF4E promotes tumorigenesis and modulates chemosensitivity to cisplatin in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.11694

Ting Liu, Rong Li, Hui Zhao, Juan Deng, Ying Long, Meng-ting Shuai, Qian Li, Huan Gu, Ya-qi Chen,  and Ai-min Leng
66851-66864
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

β-escin selectively targets the glioblastoma-initiating cell population and reduces cell viability

β-escin selectively targets the glioblastoma-initiating cell population and reduces cell viability

https://doi.org/10.18632/oncotarget.11784

Elizabeth Harford-Wright, Nicolas Bidère,  and Julie Gavard
66865-66879
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Biopsy-free circulating tumor DNA assay identifies actionable mutations in lung cancer

Biopsy-free circulating tumor DNA assay identifies actionable mutations in lung cancer

https://doi.org/10.18632/oncotarget.11801

Victoria Villaflor, Brian Won, Rebecca Nagy, Kimberly Banks, Richard B. Lanman, AmirAli Talasaz,  and Ravi Salgia
66880-66891
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Modulation of glycogen synthase kinase-3β following TRAIL combinatorial treatment in cancer cells

Modulation of glycogen synthase kinase-3β following TRAIL combinatorial treatment in cancer cells

https://doi.org/10.18632/oncotarget.11834

Sreevidya Santha, Gantulga Davaakhuu, Aninda Basu, Rong Ke, Subhasis Das, Ajay Rana,  and Basabi Rana
66892-66905
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Quantification of nucleic acid quality in postmortem tissues from a cancer research autopsy program

Quantification of nucleic acid quality in postmortem tissues from a cancer research autopsy program

https://doi.org/10.18632/oncotarget.11836

Jun Fan, Raya Khanin, Hitomi Sakamoto, Yi Zhong, Chelsea Michael, Derwin Pena, Breanna Javier, Laura D. Wood,  and Christine A. Iacobuzio-Donahue
66906-66921
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MicroRNA-126 inhibits tumor proliferation and angiogenesis of hepatocellular carcinoma by down-regulating EGFL7 expression

MicroRNA-126 inhibits tumor proliferation and angiogenesis of hepatocellular carcinoma by down-regulating EGFL7 expression

https://doi.org/10.18632/oncotarget.11877

Ming-Hua Hu, Chen-Yang Ma, Xiao-Ming Wang, Chen-Dong Ye, Guang-Xian Zhang, Lin Chen,  and Jin-Guo Wang
66922-66934
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Zinc transporters are differentially expressed in human non-small cell lung cancer

Zinc transporters are differentially expressed in human non-small cell lung cancer

https://doi.org/10.18632/oncotarget.11884

Cuiping Huang, Xiaobo Cui, Xiaotian Sun, Jingxuan Yang,  and Min Li
66935-66943
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Berberine induces autophagy in glioblastoma by targeting the AMPK/mTOR/ULK1-pathway

Berberine induces autophagy in glioblastoma by targeting the AMPK/mTOR/ULK1-pathway

https://doi.org/10.18632/oncotarget.11396

Jiwei Wang, Qichao Qi, Zichao Feng, Xin Zhang, Bin Huang, Anjing Chen, Lars Prestegarden, Xingang Li,  and Jian Wang
66944-66958
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pesticide exposure and risk of bladder cancer: A meta-analysis

Pesticide exposure and risk of bladder cancer: A meta-analysis

https://doi.org/10.18632/oncotarget.11397

Zhen Liang, Xiao Wang, Bo Xie, Yi Zhu, Jian Wu, Shiqi Li, Shuai Meng, Xiangyi Zheng, Alin Ji,  and Liping Xie
66959-66969
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Identification of breast cancer cell subtypes sensitive to ATG4B inhibition

Identification of breast cancer cell subtypes sensitive to ATG4B inhibition

https://doi.org/10.18632/oncotarget.11408

Svetlana Bortnik, Courtney Choutka, Hugo M. Horlings, Samuel Leung, Jennifer H.E. Baker, Chandra Lebovitz, Wieslawa H. Dragowska, Nancy E. Go, Marcel B. Bally, Andrew I. Minchinton, Karen A. Gelmon,  and Sharon M. Gorski
66970-66988
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-21 promotes TGF-β1-induced epithelial-mesenchymal transition in gastric cancer through up-regulating PTEN expression

MicroRNA-21 promotes TGF-β1-induced epithelial-mesenchymal transition in gastric cancer through up-regulating PTEN expression

https://doi.org/10.18632/oncotarget.11888

Chang Li, Lei Song, Zhuo Zhang, Xiao-Xue Bai, Ming-Fu Cui,  and Lian-Jun Ma
66989-67003
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Developing an anticancer copper(II) pro-drug based on the nature of cancer cell and human serum albumin carrier IIA subdomain: mouse model of breast cancer

Developing an anticancer copper(II) pro-drug based on the nature of cancer cell and human serum albumin carrier IIA subdomain: mouse model of breast cancer

https://doi.org/10.18632/oncotarget.11465

Yi Gou, Yao Zhang, Jinxu Qi, Shifang Chen, Zuping Zhou, Xiaoyang Wu, Hong Liang,  and Feng Yang
67004-67019
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Prognostic value of microRNA-9 in cancers: a systematic review and meta-analysis

Prognostic value of microRNA-9 in cancers: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.11466

Han Sun, Yingjie Shao, Jin Huang, Siwei Sun, Yijie Liu, Pinghui Zhou,  and Huilin Yang
67020-67032
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Efficacy of bortezomib in sarcomas with high levels of MAP17 (PDZK1IP1)

Efficacy of bortezomib in sarcomas with high levels of MAP17 (PDZK1IP1)

https://doi.org/10.18632/oncotarget.11475

Marco Perez, Javier Peinado-Serrano, Jose Manuel Garcia-Heredia, Irene Felipe-Abrio, Cristina Tous, Irene Ferrer, Javier Martin-Broto, Carmen Saez,  and Amancio Carnero
67033-67046
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Prognostic significance and the role in TNM stage of extranodal metastasis within regional lymph nodes station in gastric carcinoma

Prognostic significance and the role in TNM stage of extranodal metastasis within regional lymph nodes station in gastric carcinoma

https://doi.org/10.18632/oncotarget.11478

Xiao-Long Chen, Lin-Yong Zhao, Lian Xue, Yu-Hui Xu, Wei-Han Zhang, Kai Liu, Xin-Zu Chen, Kun Yang, Bo Zhang, Zhi-Xin Chen, Jia-Ping Chen, Zong-Guang Zhou,  and Jian-Kun Hu
67047-67060
Abstract  |  PDF  |  HTML  |  Order a Reprint

Potent in vitro and in vivo effects of polyclonal anti-human-myeloma globulins

Potent in vitro and in vivo effects of polyclonal anti-human-myeloma globulins

https://doi.org/10.18632/oncotarget.11489

Aneta Schieferdecker, Ofer Shoshani, Benedikt Westner, Dov Zipori, Boris Fehse, Nicolaus Kröger,  and Francis Ayuk
67061-67070
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Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer

Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer

https://doi.org/10.18632/oncotarget.11490

Jianchang Qian, Yaqing Chen, Tao Meng, Lanping Ma, Lanfang Meng, Xin Wang, Ting Yu, Arie Zask, Jingkang Shen,  and Ker Yu
67071-67086
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TLR2 ligand-synthetic long peptide conjugates effectively stimulate tumor-draining lymph node T cells of cervical cancer patients

TLR2 ligand-synthetic long peptide conjugates effectively stimulate tumor-draining lymph node T cells of cervical cancer patients

https://doi.org/10.18632/oncotarget.11512

Gijs G. Zom, Marij J.P. Welters, Nikki M. Loof, Renske Goedemans, Sinéad Lougheed, Rob R.P.M. Valentijn, Maarten L. Zandvliet, Nico J. Meeuwenoord, Cornelis J.M. Melief, Tanja D. de Gruijl, Gijsbert A. Van der Marel, Dmitri V. Filippov, Ferry Ossendorp,  and Sjoerd H. Van der Burg
67087-67100
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association between germline homeobox B13 (HOXB13) G84E allele and prostate cancer susceptibility: a meta-analysis and trial sequential analysis

Association between germline homeobox B13 (HOXB13) G84E allele and prostate cancer susceptibility: a meta-analysis and trial sequential analysis

https://doi.org/10.18632/oncotarget.11937

Jianzhong Zhang, Li Xiao, Zhiqiang Qin, Aiming Xu, Kai Zhao, Chao Liang, Chenkui Miao, Jundong Zhu, Wei Chen, Yibo Hua, Yiyang Liu, Chao Zhang, Yajie Yu, Shifeng Su,  and Zengjun Wang
67101-67110
Abstract  |  PDF  |  HTML  |  Order a Reprint

Comparative metabolic and lipidomic profiling of human breast cancer cells with different metastatic potentials

Comparative metabolic and lipidomic profiling of human breast cancer cells with different metastatic potentials

https://doi.org/10.18632/oncotarget.11560

Hye-Youn Kim, Kyung-Min Lee, So-Hyun Kim, Yeo-Jung Kwon, Young-Jin Chun,  and Hyung-Kyoon Choi
67111-67128
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

An anti-ErbB2 fully human antibody circumvents trastuzumab resistance

An anti-ErbB2 fully human antibody circumvents trastuzumab resistance

https://doi.org/10.18632/oncotarget.11562

Qiong Lu, Lingfei Wang, Yajun Zhang, Xiaojie Yu, Chao Wang, Huajing Wang, Yang Yang, Xiaodan Chong, Tian Xia, Yanchun Meng, Yuxiao Wang, Cuihua Lu, Lijun Zhou,  and Bohua Li
67129-67141
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Immune inflammation indicators and implication for immune modulation strategies in advanced hepatocellular carcinoma patients receiving sorafenib

Immune inflammation indicators and implication for immune modulation strategies in advanced hepatocellular carcinoma patients receiving sorafenib

https://doi.org/10.18632/oncotarget.11565

Andrea Casadei Gardini, Emanuela Scarpi, Luca Faloppi, Mario Scartozzi, Nicola Silvestris, Daniele Santini, Giorgio de Stefano, Giorgia Marisi, Francesca V. Negri, Francesco Giuseppe Foschi, Martina Valgiusti, Giorgio Ercolani,  and Giovanni Luca Frassineti
67142-67149
Abstract  |  PDF  |  HTML  |  Order a Reprint

Angiotensin II type I receptor (AT1R) is an independent prognosticator of esophageal squamous cell carcinoma and promotes cells proliferation via mTOR activation

Angiotensin II type I receptor (AT1R) is an independent prognosticator of esophageal squamous cell carcinoma and promotes cells proliferation via mTOR activation

https://doi.org/10.18632/oncotarget.11567

Shau-Hsuan Li, Hung-I Lu, Alice Y.W. Chang, Wan-Ting Huang, Wei-Che Lin, Ching-Chang Lee, Wan-Yu Tien, Ya-Chun Lan, Hsin-Ting Tsai,  and Chang-Han Chen
67150-67165
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CD64-directed microtubule associated protein tau kills leukemic blasts ex vivo

CD64-directed microtubule associated protein tau kills leukemic blasts ex vivo

https://doi.org/10.18632/oncotarget.11568

Radoslav Mladenov, Dmitrij Hristodorov, Christian Cremer, Gerrit Gresch, Elena Grieger, Lea Schenke, Diana Klose, Manal Amoury, Mira Woitok, Edgar Jost, Tim H. Brümmendorf, Rolf Fendel, Rainer Fischer, Christoph Stein, Theo Thepen,  and Stefan Barth
67166-67174
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumor-specific CD4+ T cells eradicate myeloma cells genetically deficient in MHC class II display

Tumor-specific CD4+ T cells eradicate myeloma cells genetically deficient in MHC class II display

https://doi.org/10.18632/oncotarget.11946

Anders Tveita, Marte Fauskanger, Bjarne Bogen,  and Ole Audun Werner Haabeth
67175-67182
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TP53 mutation hits energy metabolism and increases glycolysis in breast cancer

TP53 mutation hits energy metabolism and increases glycolysis in breast cancer

https://doi.org/10.18632/oncotarget.11594

Hajnalka Harami-Papp, Lőrinc S. Pongor, Gyöngyi Munkácsy, Gergő Horváth, Ádám M. Nagy, Attila Ambrus, Péter Hauser, András Szabó, László Tretter,  and Balázs Győrffy
67183-67195
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TGF-β1 promotes colorectal cancer immune escape by elevating B7-H3 and B7-H4 via the miR-155/miR-143 axis

TGF-β1 promotes colorectal cancer immune escape by elevating B7-H3 and B7-H4 via the miR-155/miR-143 axis

https://doi.org/10.18632/oncotarget.11950

Xinru Zhou, Yong Mao, Jianjie Zhu, Fanyi Meng, Qi Chen, Lihua Tao, Rui Li, Fengqing Fu, Cuiping Liu, Yuanjia Hu, Weipeng Wang, Hongjian Zhang, Dong Hua, Weichang Chen,  and Xueguang Zhang
67196-67211
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The overexpression of MDM4: an effective and novel predictor of gastric adenocarcinoma lymph node metastasis

The overexpression of MDM4: an effective and novel predictor of gastric adenocarcinoma lymph node metastasis

https://doi.org/10.18632/oncotarget.11971

Junjie Bao, Abiyasi Nanding, Haibin Song, Rui Xu, Guofan Qu,  and Yingwei Xue
67212-67222
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Methionine deprivation suppresses triple-negative breast cancer metastasis in vitro and in vivo

Methionine deprivation suppresses triple-negative breast cancer metastasis in vitro and in vivo

https://doi.org/10.18632/oncotarget.11615

Hyein Jeon, Jae Hwan Kim, Eunjung Lee, Young Jin Jang, Joe Eun Son, Jung Yeon Kwon, Tae-gyu Lim, Sunghoon Kim, Jung Han Yoon Park, Jong-Eun Kim,  and Ki Won Lee
67223-67234
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence

Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence

https://doi.org/10.18632/oncotarget.11972

Nancy Berte, Stefanie Lokan, Marcus Eich, Ella Kim,  and Bernd Kaina
67235-67250
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oncogenic roles of the SETDB2 histone methyltransferase in gastric cancer

Oncogenic roles of the SETDB2 histone methyltransferase in gastric cancer

https://doi.org/10.18632/oncotarget.11625

Taketo Nishikawaji, Yoshimitsu Akiyama, Shu Shimada, Kazuyuki Kojima, Tatsuyuki Kawano, Yoshinobu Eishi, Yasuhito Yuasa,  and Shinji Tanaka
67251-67265
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MTTE: an innovative strategy for the evaluation of targeted/exome enrichment efficiency

MTTE: an innovative strategy for the evaluation of targeted/exome enrichment efficiency

https://doi.org/10.18632/oncotarget.11646

Katarzyna Klonowska, Luiza Handschuh, Aleksandra Swiercz, Marek Figlerowicz,  and Piotr Kozlowski
67266-67276
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Blockade efficacy of MEK/ERK-dependent autophagy enhances PI3K/Akt inhibitor NVP-BKM120's therapeutic effectiveness in lung cancer cells

Blockade efficacy of MEK/ERK-dependent autophagy enhances PI3K/Akt inhibitor NVP-BKM120's therapeutic effectiveness in lung cancer cells

https://doi.org/10.18632/oncotarget.11645

Hui Ren, Hua Guo, Asmitananda Thakur, Shuo Zhang, Ting Wang, Yiqian Liang, Puyu Shi, Lei Gao, Feng Liu, Jing Feng, Tianjun Chen, Tian Yang, Dong Shang, Johnson J. Liu, Feng Xu,  and Mingwei Chen
67277-67287
Abstract  |  PDF  |  HTML  |  Order a Reprint

A directly negative interaction of miR-203 and ZEB2 modulates tumor stemness and chemotherapy resistance in nasopharyngeal carcinoma

A directly negative interaction of miR-203 and ZEB2 modulates tumor stemness and chemotherapy resistance in nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.11691

Qingping Jiang, Ying Zhou, Huiling Yang, Libo Li, Xiaojie Deng, Chao Cheng, Yingying Xie, Xiaojun Luo, Weiyi Fang,  and Zhen Liu
67288-67301
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Quantitative image variables reflect the intratumoral pathologic heterogeneity of lung adenocarcinoma

Quantitative image variables reflect the intratumoral pathologic heterogeneity of lung adenocarcinoma

https://doi.org/10.18632/oncotarget.11693

E-Ryung Choi, Ho Yun Lee, Ji Yun Jeong, Yoon-La Choi, Jhingook Kim, Jungmin Bae, Kyung Soo Lee,  and Young Mog Shim
67302-67313
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Early tumor shrinkage as a predictor of favorable outcomes in patients with advanced pancreatic cancer treated with FOLFIRINOX

Early tumor shrinkage as a predictor of favorable outcomes in patients with advanced pancreatic cancer treated with FOLFIRINOX

https://doi.org/10.18632/oncotarget.12007

Yasuhiro Kaga, Yu Sunakawa, Yutaro Kubota, Teppei Tagawa, Taikan Yamamoto, Toshikazu Ikusue, Yu Uto, Kouichirou Miyashita, Hirokazu Toshima, Kouji Kobayashi, Atsushi Hisamatsu, Wataru Ichikawa, Takashi Sekikawa, Ken Shimada,  and Yasutsuna Sasaki
67314-67320
Abstract  |  PDF  |  HTML  |  Order a Reprint

miR-208a-3p suppresses cell apoptosis by targeting PDCD4 in gastric cancer

miR-208a-3p suppresses cell apoptosis by targeting PDCD4 in gastric cancer

https://doi.org/10.18632/oncotarget.12006

Kai Yin, Minghui Liu, Mei Zhang, Feng Wang, Min Fen, Zhijian Liu, Yutao Yuan, Shanting Gao, Liuqing Yang, Weijie Zhang, Jianguo Zhang, Baoliang Guo, Jianwei Xu, Hongwei Liang, Xi Chen,  and Wenxian Guan
67321-67332
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The prognostic value of the myeloid-mediated immunosuppression marker Arginase-1 in classic Hodgkin lymphoma

The prognostic value of the myeloid-mediated immunosuppression marker Arginase-1 in classic Hodgkin lymphoma

https://doi.org/10.18632/oncotarget.12024

Alessandra Romano, Nunziatina Laura Parrinello, Calogero Vetro, Daniele Tibullo, Cesarina Giallongo, Piera La Cava, Annalisa Chiarenza, Giovanna Motta, Anastasia L. Caruso, Loredana Villari, Claudio Tripodo, Sebastiano Cosentino, Massimo Ippolito, Ugo Consoli, Andrea Gallamini, Stefano Pileri,  and Francesco Di Raimondo
67333-67346
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mycobacterium tuberculosis PPE32 promotes cytokines production and host cell apoptosis through caspase cascade accompanying with enhanced ER stress response

Mycobacterium tuberculosis PPE32 promotes cytokines production and host cell apoptosis through caspase cascade accompanying with enhanced ER stress response

https://doi.org/10.18632/oncotarget.12030

Wanyan Deng, Wenmin Yang, Jie Zeng, Abualgasim Elgaili Abdalla,  and Jianping Xie
67347-67359
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HLA-E expression and its clinical relevance in human renal cell carcinoma

HLA-E expression and its clinical relevance in human renal cell carcinoma

https://doi.org/10.18632/oncotarget.11744

Barbara Seliger, Simon Jasinski-Bergner, Dagmar Quandt, Christine Stoehr, Juergen Bukur, Sven Wach, Wolfgang Legal, Helge Taubert, Bernd Wullich,  and Arndt Hartmann
67360-67372
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Adenosine A3 receptor elicits chemoresistance mediated by multiple resistance-associated protein-1 in human glioblastoma stem-like cells

Adenosine A3 receptor elicits chemoresistance mediated by multiple resistance-associated protein-1 in human glioblastoma stem-like cells

https://doi.org/10.18632/oncotarget.12033

Angelo Torres, Yosselyn Vargas, Daniel Uribe, Catherine Jaramillo, Alejandra Gleisner, Flavio Salazar-Onfray, Mercedes N. López, Rómulo Melo, Carlos Oyarzún, Rody San Martín,  and Claudia Quezada
67373-67386
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cytoskeleton-centric protein transportation by exosomes transforms tumor-favorable macrophages

Cytoskeleton-centric protein transportation by exosomes transforms tumor-favorable macrophages

https://doi.org/10.18632/oncotarget.11794

Zhipeng Chen, Lijuan Yang, Yizhi Cui, Yanlong Zhou, Xingfeng Yin, Jiahui Guo, Gong Zhang, Tong Wang,  and Qing-Yu He
67387-67402
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Correlation between positron emission tomography and Cerenkov luminescence imaging in vivo and ex vivo using 64Cu-labeled antibodies in a neuroblastoma mouse model

Correlation between positron emission tomography and Cerenkov luminescence imaging in vivo and ex vivo using 64Cu-labeled antibodies in a neuroblastoma mouse model

https://doi.org/10.18632/oncotarget.11795

Florian C. Maier, Julia Schmitt, Andreas Maurer, Walter Ehrlichmann, Gerald Reischl, Konstantin Nikolaou, Rupert Handgretinger, Bernd J. Pichler,  and Wolfgang M. Thaiss
67403-67411
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The significance of c.690G>T polymorphism (rs34529039) and expression of the CEBPA gene in ovarian cancer outcome

The significance of c.690G>T polymorphism (rs34529039) and expression of the CEBPA gene in ovarian cancer outcome

https://doi.org/10.18632/oncotarget.11822

Bozena Konopka, Lukasz Michal Szafron, Ewa Kwiatkowska, Agnieszka Podgorska, Aleksandra Zolocinska, Barbara Pienkowska-Grela, Agnieszka Dansonka-Mieszkowska, Anna Balcerak, Martyna Lukasik, Anna Stachurska, Agnieszka Timorek, Beata Spiewankiewicz, Mona El-Bahrawy,  and Jolanta Kupryjanczyk
67412-67424
Abstract  |  PDF  |  HTML  |  Order a Reprint

The clinicopathological and prognostic features of Chinese and Japanese inpatients with lung cancer

The clinicopathological and prognostic features of Chinese and Japanese inpatients with lung cancer

https://doi.org/10.18632/oncotarget.11850

Yang Gao, Ji-feng Zhang, Jia-jie Liu, Li-li Liu, Xue-feng Yang, Hua-mao Jiang,  and Hua-chuan Zheng
67425-67434
Abstract  |  PDF  |  HTML  |  Order a Reprint

Detection of multiple mutations in urinary exfoliated cells from male bladder cancer patients at diagnosis and during follow-up

Detection of multiple mutations in urinary exfoliated cells from male bladder cancer patients at diagnosis and during follow-up

https://doi.org/10.18632/oncotarget.11883

Rossana Critelli, Francesca Fasanelli, Marco Oderda, Silvia Polidoro, Manuela Bianca Assumma, Clara Viberti, Mirko Preto, Paolo Gontero, Giuseppina Cucchiarale, Irene Lurkin, Ellen C. Zwarthoff, Paolo Vineis, Carlotta Sacerdote, Giuseppe Matullo,  and Alessio Naccarati
67435-67448
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HSPB1 deficiency sensitizes melanoma cells to hyperthermia induced cell death

HSPB1 deficiency sensitizes melanoma cells to hyperthermia induced cell death

https://doi.org/10.18632/oncotarget.11894

He-Xiao Wang, Yang Yang, Hao Guo, Dian-Dong Hou, Song Zheng, Yu-Xiao Hong, Yun-Fei Cai, Wei Huo, Rui-Qun Qi, Li Zhang, Hong-Duo Chen,  and Xing-Hua Gao
67449-67462
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Bladder neck preservation improves time to continence after radical prostatectomy: a systematic review and meta-analysis

Bladder neck preservation improves time to continence after radical prostatectomy: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.11997

Xueyou Ma, Kun Tang, Chunguang Yang, Guanqing Wu, Nan Xu, Meng Wang, Xing Zeng, Zhiquan Hu, Ranran Song, Bertram Yuh, Zhihua Wang,  and Zhangqun Ye
67463-67475
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical Research Papers

Reduced Connexin 43 expression is associated with tumor malignant behaviors and biochemical recurrence-free survival of prostate cancer

Reduced Connexin 43 expression is associated with tumor malignant behaviors and biochemical recurrence-free survival of prostate cancer

https://doi.org/10.18632/oncotarget.11231

Ning Xu, Hui-Jun Chen, Shao-Hao Chen, Xue-Yi Xue, Hong Chen, Qing-Shui Zheng, Yong Wei, Xiao-Dong Li, Jin-Bei Huang, Hai Cai,  and Xiong-Lin Sun
67476-67484
Abstract  |  PDF  |  HTML  |  Order a Reprint

The preoperative sensitive-modified Glasgow prognostic score is superior to the modified Glasgow prognostic score in predicting long-term survival for esophageal squamous cell carcinoma

The preoperative sensitive-modified Glasgow prognostic score is superior to the modified Glasgow prognostic score in predicting long-term survival for esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.11268

Rui Tian, Fei Zhang, Peng Sun, Jing Wu, Hong Yan, Ai-Ran Wu, Min Zhang, Yu-Lu Jiang, Yan-Hong Lu, Qiu-Yan Xu, Xiao-Hong Zhan, Rong-Xin Zhang, Li-Ting Qian,  and Jie He
67485-67494
Abstract  |  PDF  |  HTML  |  Order a Reprint

Phase I/II study of azacitidine and capecitabine/oxaliplatin (CAPOX) in refractory CIMP-high metastatic colorectal cancer: evaluation of circulating methylated vimentin

Phase I/II study of azacitidine and capecitabine/oxaliplatin (CAPOX) in refractory CIMP-high metastatic colorectal cancer: evaluation of circulating methylated vimentin

https://doi.org/10.18632/oncotarget.11317

Michael J. Overman, Van Morris, Helen Moinova, Ganiraju Manyam, Joe Ensor, Michael S. Lee, Cathy Eng, Bryan Kee, David Fogelman, Rachna T. Shroff, Thomas LaFramboise, Thibault Mazard, Tian Feng, Stanley Hamilton, Bradley Broom, James Lutterbaugh, Jean-Pierre Issa, Sanford D. Markowitz,  and Scott Kopetz
67495-67506
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical and kinomic analysis identifies peripheral blood mononuclear cells as a potential pharmacodynamic biomarker in metastatic renal cell carcinoma patients treated with sunitinib

Clinical and kinomic analysis identifies peripheral blood mononuclear cells as a potential pharmacodynamic biomarker in metastatic renal cell carcinoma patients treated with sunitinib

https://doi.org/10.18632/oncotarget.11686

Gaёlle Noé, Audrey Bellesoeur, Audrey Thomas-Schoemann, Savithri Rangarajan, Faris Naji, Alicja Puszkiel, Olivier Huillard, Nathaniel Saidu, Lisa Golmard, Jerome Alexandre, Francois Goldwasser, Benoit Blanchet,  and Michel Vidal
67507-67520
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy

Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy

https://doi.org/10.18632/oncotarget.11750

Haeseong Park, Ignacio Garrido-Laguna, Aung Naing, Siqing Fu, Gerald S. Falchook, Sarina A. Piha-Paul, Jennifer J. Wheler, David S. Hong, Apostolia M. Tsimberidou, Vivek Subbiah, Ralph G. Zinner, Ahmed O. Kaseb, Shreyaskumar Patel, Michelle A. Fanale, Vivianne M. Velez-Bravo, Funda Meric-Bernstam, Razelle Kurzrock,  and Filip Janku
67521-67531
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reviews

Protein arginine methylation/demethylation and cancer

Protein arginine methylation/demethylation and cancer

https://doi.org/10.18632/oncotarget.11376

Coralie Poulard, Laura Corbo,  and Muriel Le Romancer
67532-67550
Abstract  |  PDF  |  HTML  |  Order a Reprint

Pediatric Hodgkin lymphoma– biomarkers, drugs, and clinical trials for translational science and medicine

Pediatric Hodgkin lymphoma– biomarkers, drugs, and clinical trials for translational science and medicine

https://doi.org/10.18632/oncotarget.11509

Poonam Nagpal, Mohamed R. Akl, Nehad M. Ayoub, Tatsunari Tomiyama, Tasheka Cousins, Betty Tai, Nicole Carroll, Themba Nyrenda, Pritish Bhattacharyya, Michael B. Harris, Andre Goy, Andrew Pecora,  and K. Stephen Suh
67551-67573
Abstract  |  PDF  |  HTML  |  Order a Reprint

Roles of SPARC in urothelial carcinogenesis, progression and metastasis

Roles of SPARC in urothelial carcinogenesis, progression and metastasis

https://doi.org/10.18632/oncotarget.11590

Neveen Said
67574-67585
Abstract  |  PDF  |  HTML  |  Order a Reprint

Circulating tumor cells predict survival benefit from chemotherapy in patients with lung cancer

Circulating tumor cells predict survival benefit from chemotherapy in patients with lung cancer

https://doi.org/10.18632/oncotarget.11707

Zhuo-Xuan Wu, Zhen Liu, Han-Ling Jiang, Hong-Ming Pan,  and Wei-Dong Han
67586-67596
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNAs and epithelial-mesenchymal transition in prostate cancer

MicroRNAs and epithelial-mesenchymal transition in prostate cancer

https://doi.org/10.18632/oncotarget.11708

Kirandeep Sekhon, Nathan Bucay, Shahana Majid, Rajvir Dahiya,  and Sharanjot Saini
67597-67611
Abstract  |  PDF  |  HTML  |  Order a Reprint

Gene-gene interactions in gastrointestinal cancer susceptibility

Gene-gene interactions in gastrointestinal cancer susceptibility

https://doi.org/10.18632/oncotarget.11701

Jineun Kim, Seoyun Yum, Changwon Kang,  and Suk-Jo Kang
67612-67625
Abstract  |  PDF  |  HTML  |  Order a Reprint

On metabolic reprogramming and tumor biology: A comprehensive survey of metabolism in breast cancer

On metabolic reprogramming and tumor biology: A comprehensive survey of metabolism in breast cancer

https://doi.org/10.18632/oncotarget.11759

Judith Penkert, Tim Ripperger, Maximilian Schieck, Brigitte Schlegelberger, Doris Steinemann,  and Thomas Illig
67626-67649
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Tyrosine kinase inhibitors: friends or foe in treatment of hepatic fibrosis?

Tyrosine kinase inhibitors: friends or foe in treatment of hepatic fibrosis?

https://doi.org/10.18632/oncotarget.11767

Kai Qu, Tian Liu, Ting Lin, Xing Zhang, Ruixia Cui, Sinan Liu, Fandi Meng, Jingyao Zhang, Minghui Tai, Yong Wan,  and Chang Liu
67650-67660
Abstract  |  PDF  |  HTML  |  Order a Reprint

Incidence and risk of hypertension associated with vascular endothelial growth factor receptor tyrosine kinase inhibitors in cancer patients: a comprehensive network meta-analysis of 72 randomized controlled trials involving 30013 patients

Incidence and risk of hypertension associated with vascular endothelial growth factor receptor tyrosine kinase inhibitors in cancer patients: a comprehensive network meta-analysis of 72 randomized controlled trials involving 30013 patients

https://doi.org/10.18632/oncotarget.11813

Bo Liu, Fengxia Ding, Yang Liu, Geng Xiong, Tao Lin, Dawei He, Yuanyuan Zhang, Deying Zhang,  and Guanghui Wei
67661-67673
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Biological functions of macrophage-derived Wnt5a, and its roles in human diseases

Biological functions of macrophage-derived Wnt5a, and its roles in human diseases

https://doi.org/10.18632/oncotarget.11874

Yue Shao, Qianqian Zheng, Wei Wang, Na Xin, Xiaowen Song,  and Chenghai Zhao
67674-67684
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Corrections

Correction: From the core to beyond the margin: a genomic picture of glioblastoma intratumor heterogeneity

Correction: From the core to beyond the margin: a genomic picture of glioblastoma intratumor heterogeneity

https://doi.org/10.18632/oncotarget.12550

Marc Aubry, Marie de Tayrac, Amandine Etcheverry, Anne Clavreul, Stéphan Saikali, Philippe Menei,  and Jean Mosser
67685-67685
Correction  |  PDF


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