Oncotarget

Vol 7, No 40

October 4, 2016

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About The Cover

The cover for issue 40 of Oncotarget features Figure 7 (ALKBH5 is required for breast cancer tumorigenicity and metastasis) from Zhang, et al.

Table of Contents

Priority Research Papers

Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells

Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells

https://doi.org/10.18632/oncotarget.11743

Chuanzhao Zhang, Wanqing Iris Zhi, Haiquan Lu, Debangshu Samanta, Ivan Chen, Edward Gabrielson,  and Gregg L. Semenza
64527-64542
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T-cell epitope strength in WAP-T mouse mammary carcinomas is an important determinant in PD1/PD-L1 immune checkpoint blockade therapy

T-cell epitope strength in WAP-T mouse mammary carcinomas is an important determinant in PD1/PD-L1 immune checkpoint blockade therapy

https://doi.org/10.18632/oncotarget.11620

Michael Bruns, Jara Wanger, Udo Schumacher,  and Wolfgang Deppert
64543-64559
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p27kip1 expression limits H-Ras-driven transformation and tumorigenesis by both canonical and non-canonical mechanisms

p27kip1 expression limits H-Ras-driven transformation and tumorigenesis by both canonical and non-canonical mechanisms

https://doi.org/10.18632/oncotarget.11656

Ilenia Pellizzari, Linda Fabris, Stefania Berton, Ilenia Segatto, Francesca Citron, Sara D’Andrea, Martina Cusan, Sara Benevol, Tiziana Perin, Samuele Massarut, Vincenzo Canzonieri, Monica Schiappacassi, Barbara Belletti,  and Gustavo Baldassarre
64560-64574
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Piwil2 is reactivated by HPV oncoproteins and initiates cell reprogramming via epigenetic regulation during cervical cancer tumorigenesis

Piwil2 is reactivated by HPV oncoproteins and initiates cell reprogramming via epigenetic regulation during cervical cancer tumorigenesis

https://doi.org/10.18632/oncotarget.11810

Dingqing Feng, Keqin Yan, Ying Zhou, Haiyan Liang, Jing Liang, Weidong Zhao, Zhongjun Dong,  and Bin Ling
64575-64588
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Research Papers: Gerotarget (Focus on Aging)

Consumption of pomegranates improves synaptic function in a transgenic mice model of Alzheimer’s disease

Consumption of pomegranates improves synaptic function in a transgenic mice model of Alzheimer’s disease

https://doi.org/10.18632/oncotarget.10905

Nady Braidy, Musthafa Mohamed Essa, Anne Poljak, Subash Selvaraju, Samir Al-Adawi, Thamilarasan Manivasagm, Arokiasamy Justin Thenmozhi, Lezanne Ooi, Perminder Sachdev,  and Gilles J. Guillemin
64589-64604
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Interferon-gamma deficiency protects against aging-related goblet cell loss

Interferon-gamma deficiency protects against aging-related goblet cell loss

https://doi.org/10.18632/oncotarget.11872

Eugene A. Volpe, Johanna Tukler Henriksson, Changjun Wang, Flavia L. Barbosa, Mahira Zaheer, Xiaobo Zhang, Stephen C. Pflugfelder,  and Cintia S. de Paiva
64605-64614
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Research Papers: Pathology

Not all 1p/19q non-codeleted oligodendroglial tumors are astrocytic

Not all 1p/19q non-codeleted oligodendroglial tumors are astrocytic

https://doi.org/10.18632/oncotarget.11378

Yan-Xi Li, Zhifeng Shi, Abudumijiti Aibaidula, Hong Chen, Qisheng Tang, Kay Ka-Wai Li, Nellie Yuk-Fei Chung, Danny Tat-Ming Chan, Wai Sang Poon, Ying Mao, Jinsong Wu, Liangfu Zhou, Aden Ka-yin Chan,  and Ho-Keung Ng
64615-64630
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Laminin modification subretinal bio-scaffold remodels retinal pigment epithelium-driven microenvironment in vitro and in vivo

Laminin modification subretinal bio-scaffold remodels retinal pigment epithelium-driven microenvironment in vitro and in vivo

https://doi.org/10.18632/oncotarget.11502

Chi-Hsien Peng, Jen-Hua Chuang, Mong-Lien Wang, Yong-Yu Jhan, Ke-Hung Chien, Yu-Chien Chung, Kuo-Hsuan Hung, Chia-Ching Chang, Chao-Kuei Lee, Wei-Lien Tseng, De-Kuang Hwang, Chia-Hsien Hsu, Tai-Chi Lin, Shih-Hwa Chiou,  and Shih-Jen Chen
64631-64648
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FGF23 promotes myocardial fibrosis in mice through activation of β-catenin

FGF23 promotes myocardial fibrosis in mice through activation of β-catenin

https://doi.org/10.18632/oncotarget.11623

Huixin Hao, Xixian Li, Qingman Li, Hairuo Lin, Zhenhuan Chen, Jiahe Xie, Wanling Xuan, Wangjun Liao, Jianping Bin, Xiaobo Huang, Masafumi Kitakaze,  and Yulin Liao
64649-64664
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Stromal p16 expression is significantly increased in malignant ovarian neoplasms

Stromal p16 expression is significantly increased in malignant ovarian neoplasms

https://doi.org/10.18632/oncotarget.11660

Nara Yoon, Gun Yoon, Cheol Keun Park,  and Hyun-Soo Kim
64665-64673
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Evidence of cellular stress and caspase-3 resulting from a combined two-frequency signal in the cerebrum and cerebellum of Sprague-Dawley rats

Evidence of cellular stress and caspase-3 resulting from a combined two-frequency signal in the cerebrum and cerebellum of Sprague-Dawley rats

https://doi.org/10.18632/oncotarget.11753

Alberto López-Furelos, José Manuel Leiro-Vidal, Aarón Ángel Salas-Sánchez, Francisco José Ares-Pena,  and María Elena López-Martín
64674-64689
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Renal tubular epithelium-targeted peroxisome proliferator-activated receptor-γ maintains the epithelial phenotype and antagonizes renal fibrogenesis

Renal tubular epithelium-targeted peroxisome proliferator-activated receptor-γ maintains the epithelial phenotype and antagonizes renal fibrogenesis

https://doi.org/10.18632/oncotarget.11811

Min Zhao, Ying Chen, Guixia Ding, Ying Xu, Mi Bai, Yue Zhang, Zhanjun Jia, Songming Huang,  and Aihua Zhang
64690-64701
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Prognostic value of the Hippo pathway transcriptional coactivators YAP/TAZ and β1-integrin in conventional osteosarcoma

Prognostic value of the Hippo pathway transcriptional coactivators YAP/TAZ and β1-integrin in conventional osteosarcoma

https://doi.org/10.18632/oncotarget.11876

Corinne Bouvier, Nicolas Macagno, Quy Nguyen, Anderson Loundou, Carine Jiguet-Jiglaire, Jean-Claude Gentet, Jean-Luc Jouve, Alexandre Rochwerger, Jean-Camille Mattei, Daniel Bouvard,  and Sébastien Salas
64702-64710
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Mediation of episodic memory performance by the executive function network in patients with amnestic mild cognitive impairment: a resting-state functional MRI study

Mediation of episodic memory performance by the executive function network in patients with amnestic mild cognitive impairment: a resting-state functional MRI study

https://doi.org/10.18632/oncotarget.11775

Baoyu Yuan, Jiu Chen, Liang Gong, Hao Shu, Wenxiang Liao, Zan Wang, Duan Liu, Chunming Xie,  and Zhijun Zhang
64711-64725
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Research Papers: Immunology

Antigen specific immune response in Chlamydia muridarum genital infection is dependent on murine microRNAs-155 and -182

Antigen specific immune response in Chlamydia muridarum genital infection is dependent on murine microRNAs-155 and -182

https://doi.org/10.18632/oncotarget.11461

Rishein Gupta, Tanvi Arkatkar, Jonathon Keck, Gopala Krishna Lanka Koundinya, Kevin Castillo, Sabrina Hobel, James P. Chambers, Jieh-Juen Yu, M. Neal Guentzel, Achim Aigner, Lane K. Christenson,  and Bernard P. Arulanandam
64726-64742
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Expression of non-secreted IL-4 is associated with HDAC inhibitor-induced cell death, histone acetylation and c-Jun regulation in human gamma/delta T-cells

Expression of non-secreted IL-4 is associated with HDAC inhibitor-induced cell death, histone acetylation and c-Jun regulation in human gamma/delta T-cells

https://doi.org/10.18632/oncotarget.11462

Jaydeep Bhat, Justyna Sosna, Jürgen Fritsch, Elgar Susanne Quabius, Stefan Schütze, Sebastian Zeissig, Ole Ammerpohl, Dieter Adam,  and Dieter Kabelitz
64743-64756
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Research Papers

Validation of the Memorial Sloan Kettering Cancer Center nomogram to predict disease-specific survival in a Chinese gastric cancer population receiving postoperative chemoradiotherapy after an R0 resection

Validation of the Memorial Sloan Kettering Cancer Center nomogram to predict disease-specific survival in a Chinese gastric cancer population receiving postoperative chemoradiotherapy after an R0 resection

https://doi.org/10.18632/oncotarget.11665

Meng-long Zhou, Lei Wang, Jia-zhou Wang, Wang Yang, Ran Hu, Gui-chao Li, Wei-qi Sheng,  and Zhen Zhang
64757-64765
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Identification and validation of COX-2 as a co-target for overcoming cetuximab resistance in colorectal cancer cells

Identification and validation of COX-2 as a co-target for overcoming cetuximab resistance in colorectal cancer cells

https://doi.org/10.18632/oncotarget.8649

Yang Lu, Chunmei Shi, Songbo Qiu,  and Zhen Fan
64766-64777
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CD147 silencing inhibits tumor growth by suppressing glucose transport in melanoma

CD147 silencing inhibits tumor growth by suppressing glucose transport in melanoma

https://doi.org/10.18632/oncotarget.11415

Juan Su, Tianyuan Gao, Minghao Jiang, Lisha Wu, Weiqi Zeng, Shuang Zhao, Cong Peng,  and Xiang Chen
64778-64784
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CD45 phosphatase is crucial for human and murine acute myeloid leukemia maintenance through its localization in lipid rafts

CD45 phosphatase is crucial for human and murine acute myeloid leukemia maintenance through its localization in lipid rafts

https://doi.org/10.18632/oncotarget.11622

Laetitia Saint-Paul, Chi-Hung Nguyen, Anne Buffière, Jean-Paul Pais de Barros, Arlette Hammann, Corinne Landras-Guetta, Rodolphe Filomenko, Marie-Lorraine Chrétien, Pauline Johnson, Jean-Noël Bastie, Laurent Delva,  and Ronan Quéré
64785-64797
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Predictive and prognostic value of preoperative serum tumor markers in resectable adenosqamous lung carcinoma

Predictive and prognostic value of preoperative serum tumor markers in resectable adenosqamous lung carcinoma

https://doi.org/10.18632/oncotarget.11703

Qiongjie Zhi, Yuqian Wang, Xinyue Wang, Dongsheng Yue, Kai Li,  and Richeng Jiang
64798-64809
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p16/Ki-67 co-expression associates high risk human papillomavirus persistence and cervical histopathology: a 3-year cohort study in China

p16/Ki-67 co-expression associates high risk human papillomavirus persistence and cervical histopathology: a 3-year cohort study in China

https://doi.org/10.18632/oncotarget.11705

Lu-Lu Yu, Hui-Qin Guo, Xiao-Qin Lei, Yu Qin, Ze-Ni Wu, Le-Ni Kang, Xun Zhang, You-Lin Qiao,  and Wen Chen
64810-64819
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HuR silencing elicits oxidative stress and DNA damage and sensitizes human triple-negative breast cancer cells to radiotherapy

HuR silencing elicits oxidative stress and DNA damage and sensitizes human triple-negative breast cancer cells to radiotherapy

https://doi.org/10.18632/oncotarget.11706

Meghna Mehta, Kanthesh Basalingappa, James N. Griffith, Daniel Andrade, Anish Babu, Narsireddy Amreddy, Ranganayaki Muralidharan, Myriam Gorospe, Terence Herman, Wei-Qun Ding, Rajagopal Ramesh,  and Anupama Munshi
64820-64835
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Ovarian hormones through Wnt signalling regulate the growth of human and mouse ovarian cancer initiating lesions

Ovarian hormones through Wnt signalling regulate the growth of human and mouse ovarian cancer initiating lesions

https://doi.org/10.18632/oncotarget.11711

Prathima B. Nagendra, Jyoti Goad, Sarah Nielsen, Loui Rassam, Janine M. Lombard, Pravin Nahar,  and Pradeep S. Tanwar
64836-64853
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Bone marrow adipocytes promote the Warburg phenotype in metastatic prostate tumors via HIF-1α activation

Bone marrow adipocytes promote the Warburg phenotype in metastatic prostate tumors via HIF-1α activation

https://doi.org/10.18632/oncotarget.11712

Jonathan D. Diedrich, Erandi Rajagurubandara, Mackenzie K. Herroon, Gargi Mahapatra, Maik Hüttemann,  and Izabela Podgorski
64854-64877
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Carcinogen 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis is accelerated in Smad3 heterozygous mice compared to Smad3 wild type mice

Carcinogen 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis is accelerated in Smad3 heterozygous mice compared to Smad3 wild type mice

https://doi.org/10.18632/oncotarget.11713

Zhengxue Liu, Tanima Kundu-Roy, Isao Matsuura, Guannan Wang, Yong Lin, You-Rong Lou, Nicola J. Barnard, Xiao-Fan Wang, Mou-Tuan Huang, Nanjoo Suh,  and Fang Liu
64878-64885
Abstract  |  PDF  |  HTML  |  Order a Reprint

An oncogenic role for sphingosine kinase 2

An oncogenic role for sphingosine kinase 2

https://doi.org/10.18632/oncotarget.11714

Heidi A. Neubauer, Duyen H. Pham, Julia R. Zebol, Paul A.B. Moretti, Amanda L. Peterson, Tamara M. Leclercq, Huasheng Chan, Jason A. Powell, Melissa R. Pitman, Michael S. Samuel, Claudine S. Bonder, Darren J. Creek, Briony L. Gliddon,  and Stuart M. Pitson
64886-64899
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High expression of microRNA-454 is associated with poor prognosis in triple-negative breast cancer

High expression of microRNA-454 is associated with poor prognosis in triple-negative breast cancer

https://doi.org/10.18632/oncotarget.11764

Zhi-Gang Cao, Jun-Jing Li, Ling Ya, Yan-Ni Huang, Yi-Rong Liu, Xin Hu, Chuan-Gui Song,  and Zhi-Ming Shao
64900-64909
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Immunohistochemical correlates of TP53 somatic mutations in cancer

Immunohistochemical correlates of TP53 somatic mutations in cancer

https://doi.org/10.18632/oncotarget.11912

Balázs Murnyák,  and Tibor Hortobágyi
64910-64920
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer

The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer

https://doi.org/10.18632/oncotarget.11915

Shan Wang, Rahul K. Kollipara, Caroline G. Humphries, Shi-Hong Ma, Ryan Hutchinson, Rui Li, Javed Siddiqui, Scott A. Tomlins, Ganesh V. Raj,  and Ralf Kittler
64921-64931
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-29 regulates Tet1 expression and contributes to early differentiation of mouse ESCs

miR-29 regulates Tet1 expression and contributes to early differentiation of mouse ESCs

https://doi.org/10.18632/oncotarget.10751

Yanhua Cui, Ting Li, Dehua Yang, Song Li,  and Weidong Le
64932-64941
Abstract  |  PDF  |  HTML  |  Order a Reprint

Synthetic ligands of death receptor 5 display a cell-selective agonistic effect at different oligomerization levels

Synthetic ligands of death receptor 5 display a cell-selective agonistic effect at different oligomerization levels

https://doi.org/10.18632/oncotarget.10508

Julien Beyrath, Neila Chekkat, Cristian R. Smulski, Caterina M. Lombardo, Marie-Charlotte Lechner, Cendrine Seguin, Marion Decossas, Maria Vittoria Spanedda, Benoît Frisch, Gilles Guichard,  and Sylvie Fournel
64942-64956
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Neuraminidase 1 (NEU1) promotes proliferation and migration as a diagnostic and prognostic biomarker of hepatocellular carcinoma

Neuraminidase 1 (NEU1) promotes proliferation and migration as a diagnostic and prognostic biomarker of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.11778

Guojun Hou, Gang Liu, Yuan Yang, Yixue Li, Shengxian Yuan, Linghao Zhao, Mengchao Wu, Lei Liu,  and Weiping Zhou
64957-64966
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Discovery of peptide inhibitors targeting human programmed death 1 (PD-1) receptor

Discovery of peptide inhibitors targeting human programmed death 1 (PD-1) receptor

https://doi.org/10.18632/oncotarget.11274

Qiao Li, Lina Quan, Jiankun Lyu, Zenghui He, Xia Wang, Jiajia Meng, Zhenjiang Zhao, Lili Zhu, Xiaofeng Liu,  and Honglin Li
64967-64976
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Proto-oncogenic miR-744 is upregulated by transcription factor c-Jun via a promoter activation mechanism

Proto-oncogenic miR-744 is upregulated by transcription factor c-Jun via a promoter activation mechanism

https://doi.org/10.18632/oncotarget.11285

Zhou Sha, Xiaoxia Zhu, Na Li, Yiyi Li,  and Dianhe Li
64977-64986
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting prohibitins induces apoptosis in acute myeloid leukemia cells

Targeting prohibitins induces apoptosis in acute myeloid leukemia cells

https://doi.org/10.18632/oncotarget.11333

Helena Pomares, Claudia M. Palmeri, Daniel Iglesias-Serret, Cristina Moncunill-Massaguer, José Saura-Esteller, Sonia Núñez-Vázquez, Enric Gamundi, Montserrat Arnan, Sara Preciado, Fernando Albericio, Rodolfo Lavilla, Gabriel Pons, Eva M. González-Barca, Ana M. Cosialls,  and Joan Gil
64987-65000
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Drp1-mediated mitochondrial fission promotes cell proliferation through crosstalk of p53 and NF-κB pathways in hepatocellular carcinoma

Drp1-mediated mitochondrial fission promotes cell proliferation through crosstalk of p53 and NF-κB pathways in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.11339

Lei Zhan, Haiyan Cao, Gang Wang, Yinghua Lyu, Xiacheng Sun, Jiaze An, Zhenbiao Wu, Qichao Huang, Bingrong Liu,  and Jinliang Xing
65001-65011
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Antineoplastic effects and mechanisms of micheliolide in acute myelogenous leukemia stem cells

Antineoplastic effects and mechanisms of micheliolide in acute myelogenous leukemia stem cells

https://doi.org/10.18632/oncotarget.11342

Qing Ji, Ya-hui Ding, Yue Sun, Yu Zhang, Hui-er Gao, He-nan Song, Ming Yang, Xiao-lei Liu, Zi-xiang Zhang, Ying-hui Li,  and Ying-dai Gao
65012-65023
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Luminal B breast cancer: patterns of recurrence and clinical outcome

Luminal B breast cancer: patterns of recurrence and clinical outcome

https://doi.org/10.18632/oncotarget.11344

Zhi-hua Li, Ping-hua Hu, Jian-hong Tu,  and Ni-si Yu
65024-65033
Abstract  |  PDF  |  HTML  |  Order a Reprint

Influence of wound fluid on chemotherapy sensitivity in primary breast cancer cells

Influence of wound fluid on chemotherapy sensitivity in primary breast cancer cells

https://doi.org/10.18632/oncotarget.11345

Yingchao Zhang, Dong Yan, Hao Zhang, Xunyan Ou, Zuowei Zhao, Dan Wang,  and Caigang Liu
65034-65041
Abstract  |  PDF  |  HTML  |  Order a Reprint

Radiofrequency hyperthermia promotes the therapeutic effects on chemotherapeutic-resistant breast cancer when combined with heat shock protein promoter-controlled HSV-TK gene therapy: Toward imaging-guided interventional gene therapy

Radiofrequency hyperthermia promotes the therapeutic effects on chemotherapeutic-resistant breast cancer when combined with heat shock protein promoter-controlled HSV-TK gene therapy: Toward imaging-guided interventional gene therapy

https://doi.org/10.18632/oncotarget.11346

Jingfeng Luo, Xiaotian Wu, Fei Zhou, Yurong Zhou, Tongchun Huang, Fei Liu, Guocan Han, Luming Chen, Weixian Bai, Xia Wu, Jihong Sun,  and Xiaoming Yang
65042-65051
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevated CXCL1 increases hepatocellular carcinoma aggressiveness and is inhibited by miRNA-200a

Elevated CXCL1 increases hepatocellular carcinoma aggressiveness and is inhibited by miRNA-200a

https://doi.org/10.18632/oncotarget.11350

Xiao Cui, Zhao Li, Jie Gao, Peng-Ji Gao, Yan-bing Ni,  and Ji-Ye Zhu
65052-65066
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dysregulation of the BRCA1/long non-coding RNA NEAT1 signaling axis contributes to breast tumorigenesis

Dysregulation of the BRCA1/long non-coding RNA NEAT1 signaling axis contributes to breast tumorigenesis

https://doi.org/10.18632/oncotarget.11364

Pang-Kuo Lo, Yongshu Zhang, Benjamin Wolfson, Ramkishore Gernapudi, Yuan Yao, Nadire Duru,  and Qun Zhou
65067-65089
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dux4 controls migration of mesenchymal stem cells through the Cxcr4-Sdf1 axis

Dux4 controls migration of mesenchymal stem cells through the Cxcr4-Sdf1 axis

https://doi.org/10.18632/oncotarget.11368

Petr Dmitriev, Ekaterina Kiseleva, Olga Kharchenko, Evgeny Ivashkin, Andrei Pichugin, Philippe Dessen, Thomas Robert, Frédérique Coppée, Alexandra Belayew, Gilles Carnac, Dalila Laoudj-Chenivesse, Marc Lipinski, Andrei Vasiliev,  and Yegor S. Vassetzky
65090-65108
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ligand-activated PPARγ downregulates CXCR4 gene expression through a novel identified PPAR response element and inhibits breast cancer progression

Ligand-activated PPARγ downregulates CXCR4 gene expression through a novel identified PPAR response element and inhibits breast cancer progression

https://doi.org/10.18632/oncotarget.11371

Daniela Rovito, Giulia Gionfriddo, Ines Barone, Cinzia Giordano, Fedora Grande, Francesca De Amicis, Marilena Lanzino, Stefania Catalano, Sebastiano Andò,  and Daniela Bonofiglio
65109-65124
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Tumor treating fields inhibit glioblastoma cell migration, invasion and angiogenesis

Tumor treating fields inhibit glioblastoma cell migration, invasion and angiogenesis

https://doi.org/10.18632/oncotarget.11372

Eun Ho Kim, Hyo Sook Song, Seung Hoon Yoo,  and Myonggeun Yoon
65125-65136
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The ELK3-GATA3 axis orchestrates invasion and metastasis of breast cancer cells in vitro and in vivo

The ELK3-GATA3 axis orchestrates invasion and metastasis of breast cancer cells in vitro and in vivo

https://doi.org/10.18632/oncotarget.11427

Sun-Young Kong, Kwang-Soo Kim, Jiewan Kim, Min Kyeong Kim, Ki Hong Lee, Je-Yong Lee, Nuri Oh, Ji-In Park, Ji-Hoon Park, Sun-Hee Heo, Sung Han Shim, Dong Ryul Lee, Keun Pil Kim,  and Kyung-Soon Park
65137-65146
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RALB provides critical survival signals downstream of Ras in acute myeloid leukemia

RALB provides critical survival signals downstream of Ras in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.11431

Craig E. Eckfeldt, Emily J. Pomeroy, Robin D.W. Lee, Katherine S. Hazen, Lindsey A. Lee, Branden S. Moriarity,  and David A. Largaespada
65147-65156
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Co-inhibition of pol θ and HR genes efficiently synergize with cisplatin to suppress cisplatin-resistant lung cancer cells survival

Co-inhibition of pol θ and HR genes efficiently synergize with cisplatin to suppress cisplatin-resistant lung cancer cells survival

https://doi.org/10.18632/oncotarget.11214

Chun-Hua Dai, Ping Chen, Jian Li, Tin Lan, Yong-Chang Chen, Hai Qian, Kang Chen,  and Mei-Yu Li
65157-65170
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A Pyrazolo[3,4-d]pyrimidine compound inhibits Fyn phosphorylation and induces apoptosis in natural killer cell leukemia

A Pyrazolo[3,4-d]pyrimidine compound inhibits Fyn phosphorylation and induces apoptosis in natural killer cell leukemia

https://doi.org/10.18632/oncotarget.11496

Ilaria Laurenzana, Antonella Caivano, Stefania Trino, Luciana De Luca, Francesco La Rocca, Vittorio Simeon, Cristina Tintori, Francesca D’Alessio, Antonella Teramo, Renato Zambello, Antonio Traficante, Maddalena Maietti, Gianpietro Semenzato, Silvia Schenone, Maurizio Botta, Pellegrino Musto,  and Luigi Del Vecchio
65171-65184
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical outcomes of advanced non-small-cell lung cancer patients with EGFR mutation, ALK rearrangement and EGFR/ALK co-alterations

Clinical outcomes of advanced non-small-cell lung cancer patients with EGFR mutation, ALK rearrangement and EGFR/ALK co-alterations

https://doi.org/10.18632/oncotarget.11218

Na-Na Lou, Xu-Chao Zhang, Hua-Jun Chen, Qing Zhou, Li-Xu Yan, Zhi Xie, Jian Su, Zhi-Hong Chen, Hai-Yan Tu, Hong-Hong Yan, Zhen Wang, Chong-Rui Xu, Ben-Yuan Jiang, Bin-Chao Wang, Xiao-Yan Bai, Wen-Zhao Zhong, Yi-Long Wu,  and Jin-Ji Yang
65185-65195
Abstract  |  PDF  |  HTML  |  Order a Reprint

Association of nonsteroidal anti-inflammatory drugs and aspirin use and the risk of head and neck cancers: a meta-analysis of observational studies

Association of nonsteroidal anti-inflammatory drugs and aspirin use and the risk of head and neck cancers: a meta-analysis of observational studies

https://doi.org/10.18632/oncotarget.11239

Lanhua Tang, Huabin Hu, Huai Liu, Chengzhu Jian, Hui Wang,  and Jin Huang
65196-65207
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Noninvasive genotyping and monitoring of anaplastic lymphoma kinase (ALK) rearranged non-small cell lung cancer by capture-based next-generation sequencing

Noninvasive genotyping and monitoring of anaplastic lymphoma kinase (ALK) rearranged non-small cell lung cancer by capture-based next-generation sequencing

https://doi.org/10.18632/oncotarget.11569

Ye Wang, Pan-Wen Tian, Wei-Ya Wang, Ke Wang, Zhou Zhang, Bo-Jiang Chen, Yan-Qi He, Lei Li, Hao Liu, Shannon Chuai,  and Wei-Min Li
65208-65217
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SIRT1-mediated FoxOs pathways protect against apoptosis by promoting autophagy in osteoblast-like MC3T3-E1 cells exposed to sodium fluoride

SIRT1-mediated FoxOs pathways protect against apoptosis by promoting autophagy in osteoblast-like MC3T3-E1 cells exposed to sodium fluoride

https://doi.org/10.18632/oncotarget.11573

Xiaolong Gu, Dandan Han, Wei Chen, Limei Zhang, Qianyun Lin, Jian Gao, Séamus Fanning,  and Bo Han
65218-65230
Abstract  |  PDF  |  HTML  |  Order a Reprint

O-mannosylation and N-glycosylation: two coordinated mechanisms regulating the tumour suppressor functions of E-cadherin in cancer

O-mannosylation and N-glycosylation: two coordinated mechanisms regulating the tumour suppressor functions of E-cadherin in cancer

https://doi.org/10.18632/oncotarget.11245

Sandra Carvalho, Tiago Oliveira, Markus F. Bartels, Eiji Miyoshi, Michael Pierce, Naoyuki Taniguchi, Fátima Carneiro, Raquel Seruca, Celso A. Reis, Sabine Strahl,  and Salomé S. Pinho
65231-65246
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The elevated preoperative fasting blood glucose predicts a poor prognosis in patients with esophageal squamous cell carcinoma: The Fujian prospective investigation of cancer (FIESTA) study

The elevated preoperative fasting blood glucose predicts a poor prognosis in patients with esophageal squamous cell carcinoma: The Fujian prospective investigation of cancer (FIESTA) study

https://doi.org/10.18632/oncotarget.11247

Dan Hu, Feng Peng, Xiandong Lin, Gang Chen, Binying Liang, Chao Li, Hejun Zhang, Xuehong Liao, Jinxiu Lin, Xiongwei Zheng,  and Wenquan Niu
65247-65256
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HGIMDA: Heterogeneous graph inference for miRNA-disease association prediction

HGIMDA: Heterogeneous graph inference for miRNA-disease association prediction

https://doi.org/10.18632/oncotarget.11251

Xing Chen, Chenggang Clarence Yan, Xu Zhang, Zhu-Hong You, Yu-An Huang,  and Gui-Ying Yan
65257-65269
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Statins dose-dependently exert a significant chemopreventive effect on colon cancer in patients with chronic obstructive pulmonary disease: A population-based cohort study

Statins dose-dependently exert a significant chemopreventive effect on colon cancer in patients with chronic obstructive pulmonary disease: A population-based cohort study

https://doi.org/10.18632/oncotarget.11263

Ju-Chi Liu, Wen-Rui Hao, Yi-Ping Hsu, Li-Chin Sung, Pai-Feng Kao, Chao-Feng Lin, Alexander T.H. Wu, Kevin Sheng-Po Yuan,  and Szu-Yuan Wu
65270-65283
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GATA3 expression correlates with poor prognosis and tumor-associated macrophage infiltration in peripheral T cell lymphoma

GATA3 expression correlates with poor prognosis and tumor-associated macrophage infiltration in peripheral T cell lymphoma

https://doi.org/10.18632/oncotarget.11673

Wei Editor, Zi Wang, Yunping Luo, Dingrong Zhong, Yufeng Luo,  and Daobin Zhou
65284-65294
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The mitochondrial and endoplasmic reticulum pathways involved in the apoptosis of bursa of Fabricius cells in broilers exposed to dietary aflatoxin B1

The mitochondrial and endoplasmic reticulum pathways involved in the apoptosis of bursa of Fabricius cells in broilers exposed to dietary aflatoxin B1

https://doi.org/10.18632/oncotarget.11321

Shibin Yuan, Bangyuan Wu, Zhengqiang Yu, Jing Fang, Na Liang, Mingqiang Zhou, Cheng Huang,  and Xi Peng
65295-65306
Abstract  |  PDF  |  HTML  |  Order a Reprint

MIEN1 is tightly regulated by SINE Alu methylation in its promoter

MIEN1 is tightly regulated by SINE Alu methylation in its promoter

https://doi.org/10.18632/oncotarget.11675

Smrithi Rajendiran, Lee D. Gibbs, Timothy Van Treuren, David L. Klinkebiel,  and Jamboor K. Vishwanatha
65307-65319
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nucleolin-binding by ErbB2 enhances tumorigenicity of ErbB2-positive breast cancer

Nucleolin-binding by ErbB2 enhances tumorigenicity of ErbB2-positive breast cancer

https://doi.org/10.18632/oncotarget.11323

Eya Wolfson, Maria Goldenberg, Shira Solomon, Amit Frishberg,  and Ronit Pinkas-Kramarski
65320-65334
Abstract  |  PDF  |  HTML  |  Order a Reprint

Endoplasmic reticulum-Golgi intermediate compartment protein 3 knockdown suppresses lung cancer through endoplasmic reticulum stress-induced autophagy

Endoplasmic reticulum-Golgi intermediate compartment protein 3 knockdown suppresses lung cancer through endoplasmic reticulum stress-induced autophagy

https://doi.org/10.18632/oncotarget.11678

Seong-Ho Hong, Seung-Hee Chang, Kyung-Cho Cho, Sanghwa Kim, Sungjin Park, Ah Young Lee, Hu-Lin Jiang, Hyeon-Jeong Kim, Somin Lee, Kyeong-Nam Yu, Hwi Won Seo, Chanhee Chae, Kwang Pyo Kim, Jongsun Park,  and Myung-Haing Cho
65335-65347
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cell-permeable iron inhibits vascular endothelial growth factor receptor-2 signaling and tumor angiogenesis

Cell-permeable iron inhibits vascular endothelial growth factor receptor-2 signaling and tumor angiogenesis

https://doi.org/10.18632/oncotarget.11689

Devika Kir, Manju Saluja, Shrey Modi, Annapoorna Venkatachalam, Erica Schnettler, Sabita Roy,  and Sundaram Ramakrishnan
65348-65363
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Concordance between genomic alterations assessed by next-generation sequencing in tumor tissue or circulating cell-free DNA

Concordance between genomic alterations assessed by next-generation sequencing in tumor tissue or circulating cell-free DNA

https://doi.org/10.18632/oncotarget.11692

Young Kwang Chae, Andrew A. Davis, Benedito A. Carneiro, Sunandana Chandra, Nisha Mohindra, Aparna Kalyan, Jason Kaplan, Maria Matsangou, Sachin Pai, Ricardo Costa, Borko Jovanovic, Massimo Cristofanilli, Leonidas C. Platanias,  and Francis J. Giles
65364-65373
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ST6Gal-I overexpression facilitates prostate cancer progression via the PI3K/Akt/GSK-3β/β-catenin signaling pathway

ST6Gal-I overexpression facilitates prostate cancer progression via the PI3K/Akt/GSK-3β/β-catenin signaling pathway

https://doi.org/10.18632/oncotarget.11699

Anwen Wei, Bo Fan, Yujie Zhao, Han Zhang, Liping Wang, Xiao Yu, Qingmin Yuan, Deyong Yang,  and Shujing Wang
65374-65388
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activation of AKT pathway by Nrf2/PDGFA feedback loop contributes to HCC progression

Activation of AKT pathway by Nrf2/PDGFA feedback loop contributes to HCC progression

https://doi.org/10.18632/oncotarget.11700

Danyang Liu, Yonglong Zhang, Yingze Wei, Guoyuan Liu, Yufeng Liu, Qiongmei Gao, Liping Zou, Wenjiao Zeng,  and Nong Zhang
65389-65402
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Foxp3 enhances HIF-1α target gene expression in human bladder cancer through decreasing its ubiquitin-proteasomal degradation

Foxp3 enhances HIF-1α target gene expression in human bladder cancer through decreasing its ubiquitin-proteasomal degradation

https://doi.org/10.18632/oncotarget.11395

Yeong-Chin Jou, Yuh-Shyan Tsai, Chang-Te Lin, Chun-Liang Tung, Cheng-Huang Shen, Hsin-Tzu Tsai, Wen-Horng Yang, Hung-I Chang, Syue-Yi Chen,  and Tzong-Shin Tzai
65403-65417
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cross-linked hyaluronic acid gel inhibits metastasis and growth of gastric and hepatic cancer cells: in vitro and in vivo studies

Cross-linked hyaluronic acid gel inhibits metastasis and growth of gastric and hepatic cancer cells: in vitro and in vivo studies

https://doi.org/10.18632/oncotarget.11739

Ting Lan, Ji Pang, Yan Wu, Miaolin Zhu, Xiaoyuan Yao, Min Wu, Hai Qian, Zhenyu Zhang, Jizong Gao,  and Yongchang Chen
65418-65428
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumor vessel normalization after aerobic exercise enhances chemotherapeutic efficacy

Tumor vessel normalization after aerobic exercise enhances chemotherapeutic efficacy

https://doi.org/10.18632/oncotarget.11748

Keri L. Schadler, Nicholas J. Thomas, Peter A. Galie, Dong Ha Bhang, Kerry C. Roby, Prince Addai, Jacob E. Till, Kathleen Sturgeon, Alexander Zaslavsky, Christopher S. Chen,  and Sandra Ryeom
65429-65440
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Leptin promotes migration and invasion of breast cancer cells by stimulating IL-8 production in M2 macrophages

Leptin promotes migration and invasion of breast cancer cells by stimulating IL-8 production in M2 macrophages

https://doi.org/10.18632/oncotarget.11761

Hong Cao, Yunxiu Huang, Lin Wang, Hong Wang, Xueli Pang, Kuangfa Li, Weiqi Dang, Hao Tang, Lan Wei, Min Su, Cuiping Tang,  and Tingmei Chen
65441-65453
Abstract  |  PDF  |  HTML  |  Order a Reprint

Hypoxia-responsive miR-210 promotes self-renewal capacity of colon tumor-initiating cells by repressing ISCU and by inducing lactate production

Hypoxia-responsive miR-210 promotes self-renewal capacity of colon tumor-initiating cells by repressing ISCU and by inducing lactate production

https://doi.org/10.18632/oncotarget.11772

Pit Ullmann, Komal Qureshi-Baig, Fabien Rodriguez, Aurélien Ginolhac, Yannic Nonnenmacher, Dominik Ternes, Jil Weiler, Karoline Gäbler, Christelle Bahlawane, Karsten Hiller, Serge Haan,  and Elisabeth Letellier
65454-65470
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TGFβ upregulates PAR-1 expression and signalling responses in A549 lung adenocarcinoma cells

TGFβ upregulates PAR-1 expression and signalling responses in A549 lung adenocarcinoma cells

https://doi.org/10.18632/oncotarget.11472

Natalia Smoktunowicz, Manuela Platé, Alejandro Ortiz Stern, Vanessa D’Antongiovanni, Eifion Robinson, Vijay Chudasama, Stephen Caddick, Chris J. Scotton, Gabor Jarai,  and Rachel C. Chambers
65471-65484
Abstract  |  PDF  |  HTML  |  Order a Reprint

Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations

Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations

https://doi.org/10.18632/oncotarget.11796

Jean-François Spinella, Pauline Cassart, Chantal Richer, Virginie Saillour, Manon Ouimet, Sylvie Langlois, Pascal St-Onge, Thomas Sontag, Jasmine Healy, Mark D. Minden,  and Daniel Sinnett
65485-65503
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting DNA double strand break repair with hyperthermia and DNA-PKcs inhibition to enhance the effect of radiation treatment

Targeting DNA double strand break repair with hyperthermia and DNA-PKcs inhibition to enhance the effect of radiation treatment

https://doi.org/10.18632/oncotarget.11798

Bregje van Oorschot, Giovanna Granata, Simone Di Franco, Rosemarie ten Cate, Hans M. Rodermond, Matilde Todaro, Jan Paul Medema,  and Nicolaas A.P. Franken
65504-65513
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

c-Myc targeted regulators of cell metabolism in a transgenic mouse model of papillary lung adenocarcinoma

c-Myc targeted regulators of cell metabolism in a transgenic mouse model of papillary lung adenocarcinoma

https://doi.org/10.18632/oncotarget.11804

Yari Ciribilli, Prashant Singh, Alberto Inga,  and Jürgen Borlak
65514-65539
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma

STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma

https://doi.org/10.18632/oncotarget.11869

Christine M. Heske, Arnulfo Mendoza, Leah D. Edessa, Joshua T. Baumgart, Sunmin Lee, Jane Trepel, David A. Proia, Len Neckers,  and Lee J. Helman
65540-65552
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Role of RbBP5 and H3K4me3 in the vicinity of Snail transcription start site during epithelial-mesenchymal transition in prostate cancer cell

Role of RbBP5 and H3K4me3 in the vicinity of Snail transcription start site during epithelial-mesenchymal transition in prostate cancer cell

https://doi.org/10.18632/oncotarget.11549

Dong Li, Hui Sun, Wen-jing Sun, Hong-bo Bao, Shu-han Si, Jia-lin Fan, Ping Lin, Rong-jun Cui, Yu-jia Pan, Si-min Wen, Xiu-lan Zheng,  and Xiao-guang Yu
65553-65567
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The prognostic value of D-dimer levels in metastatic osteosarcoma patients treated with second-line chemotherapy

The prognostic value of D-dimer levels in metastatic osteosarcoma patients treated with second-line chemotherapy

https://doi.org/10.18632/oncotarget.11571

Yujing Huang, Bangjian Liu, Yuanjue Sun, Jianjun Zhang, Yang Yao,  and Aina He
65568-65576
Abstract  |  PDF  |  HTML  |  Order a Reprint

The use of and adherence to CTCAE v3.0 in cancer clinical trial publications

The use of and adherence to CTCAE v3.0 in cancer clinical trial publications

https://doi.org/10.18632/oncotarget.11576

Sheng Zhang, Qiang Chen,  and Qing Wang
65577-65588
Abstract  |  PDF  |  HTML  |  Order a Reprint

Paradoxical overexpression of MBNL2 in hepatocellular carcinoma inhibits tumor growth and invasion

Paradoxical overexpression of MBNL2 in hepatocellular carcinoma inhibits tumor growth and invasion

https://doi.org/10.18632/oncotarget.11577

Yu-Hsin Lee, Yu-Lin Jhuang, Yu-Ling Chen, Yung-Ming Jeng,  and Ray-Hwang Yuan
65589-65601
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Role of EGF/ERBB1 in the transcriptional regulation of the prolactin receptor independent of estrogen and prolactin in breast cancer cells

Role of EGF/ERBB1 in the transcriptional regulation of the prolactin receptor independent of estrogen and prolactin in breast cancer cells

https://doi.org/10.18632/oncotarget.11579

Raghuveer Kavarthapu,  and Maria L. Dufau
65602-65613
Abstract  |  PDF  |  HTML  |  Order a Reprint

Glutathione may have implications in the design of 3-bromopyruvate treatment protocols for both fungal and algal infections as well as multiple myeloma

Glutathione may have implications in the design of 3-bromopyruvate treatment protocols for both fungal and algal infections as well as multiple myeloma

https://doi.org/10.18632/oncotarget.11592

Katarzyna Niedźwiecka, Mariusz Dyląg, Daria Augustyniak, Grażyna Majkowska-Skrobek, Magdalena Cal-Bąkowska, Young H. Ko, Peter L. Pedersen, Andre Goffeau,  and Stanisław Ułaszewski
65614-65626
Abstract  |  PDF  |  HTML  |  Order a Reprint

Evaluation of in vitro effects of various targeted drugs on plasma cells and putative neoplastic stem cells in patients with multiple myeloma

Evaluation of in vitro effects of various targeted drugs on plasma cells and putative neoplastic stem cells in patients with multiple myeloma

https://doi.org/10.18632/oncotarget.11593

Katharina Blatt, Harald Herrmann, Gabriele Stefanzl, Wolfgang R. Sperr,  and Peter Valent
65627-65642
Abstract  |  PDF  |  HTML  |  Order a Reprint

Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A)

Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A)

https://doi.org/10.18632/oncotarget.11595

Junjeong Choi, Ji-Hyun Lee, Ilkyoo Koh, Jin-Kyoung Shim, Junseong Park, Jeong Yong Jeon, Mijin Yun, Se Hoon Kim, Jong In Yook, Eui Hyun Kim, Jong Hee Chang, Sun Ho Kim, Yong Min Huh, Su Jae Lee, Michael Pollak, Pilnam Kim, Seok-Gu Kang,  and Jae-Ho Cheong
65643-65659
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activation of autophagic flux by epigallocatechin gallate mitigates TRAIL-induced tumor cell apoptosis via down-regulation of death receptors

Activation of autophagic flux by epigallocatechin gallate mitigates TRAIL-induced tumor cell apoptosis via down-regulation of death receptors

https://doi.org/10.18632/oncotarget.11597

Sung-Wook Kim, Ji-Hong Moon,  and Sang-Youel Park
65660-65668
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dietary energy restriction reduces high-fat diet-enhanced metastasis of Lewis lung carcinoma in mice

Dietary energy restriction reduces high-fat diet-enhanced metastasis of Lewis lung carcinoma in mice

https://doi.org/10.18632/oncotarget.11598

Sneha Sundaram,  and Lin Yan
65669-65675
Abstract  |  PDF  |  HTML  |  Order a Reprint

SHP-2 phosphatase contributes to KRAS-driven intestinal oncogenesis but prevents colitis-associated cancer development

SHP-2 phosphatase contributes to KRAS-driven intestinal oncogenesis but prevents colitis-associated cancer development

https://doi.org/10.18632/oncotarget.11601

Jessica Gagné-Sansfaçon, Geneviève Coulombe, Marie-Josée Langlois, Ariane Langlois, Marilene Paquet, Julie Carrier, Gen-Sheng Feng, Cheng-Kui Qu,  and Nathalie Rivard
65676-65695
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma

Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma

https://doi.org/10.18632/oncotarget.11602

Carl Koschmann, Daniel Zamler, Alan MacKay, Dan Robinson, Yi-Mi Wu, Robert Doherty, Bernard Marini, Dustin Tran, Hugh Garton, Karin Muraszko, Patricia Robertson, Marcia Leonard, Lili Zhao, Dale Bixby, Luke Peterson, Sandra Camelo-Piragua, Chris Jones, Rajen Mody, Pedro R. Lowenstein,  and Maria G. Castro
65696-65706
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Eupafolin enhances TRAIL-mediated apoptosis through cathepsin S-induced down-regulation of Mcl-1 expression and AMPK-mediated Bim up-regulation in renal carcinoma Caki cells

Eupafolin enhances TRAIL-mediated apoptosis through cathepsin S-induced down-regulation of Mcl-1 expression and AMPK-mediated Bim up-regulation in renal carcinoma Caki cells

https://doi.org/10.18632/oncotarget.11604

Min Ae Han, Kyoung-jin Min, Seon Min Woo, Bo Ram Seo,  and Taeg Kyu Kwon
65707-65720
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Superior anti-tumor efficacy of diisopropylamine dichloroacetate compared with dichloroacetate in a subcutaneous transplantation breast tumor model

Superior anti-tumor efficacy of diisopropylamine dichloroacetate compared with dichloroacetate in a subcutaneous transplantation breast tumor model

https://doi.org/10.18632/oncotarget.11609

Lei Su, Hailin Zhang, Chen Yan, Aiping Chen, Gang Meng, Jiwu Wei, Decai Yu,  and Yitao Ding
65721-65731
Abstract  |  PDF  |  HTML  |  Order a Reprint

Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase

Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase

https://doi.org/10.18632/oncotarget.11610

Xinhua Song, Shutao Yin, Enxiang Zhang, Lihong Fan, Min Ye, Yong Zhang,  and Hongbo Hu
65732-65743
Abstract  |  PDF  |  HTML  |  Order a Reprint

Decreased miR-320a promotes invasion and metastasis of tumor budding cells in tongue squamous cell carcinoma

Decreased miR-320a promotes invasion and metastasis of tumor budding cells in tongue squamous cell carcinoma

https://doi.org/10.18632/oncotarget.11612

Nan Xie, Cheng Wang, Zehang Zhuang, Jinson Hou, Xiqiang Liu, Yue Wu, Haichao Liu,  and Hongzhang Huang
65744-65757
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Novel association of DJ-1 with HER3 potentiates HER3 activation and signaling in cancer

Novel association of DJ-1 with HER3 potentiates HER3 activation and signaling in cancer

https://doi.org/10.18632/oncotarget.11613

Shu Zhang, Seema Mukherjee, Xuejun Fan, Ahmad Salameh, Kalpana Mujoo, Zhao Huang, Leike Li, Georgina To’a Salazar, Ningyan Zhang,  and Zhiqiang An
65758-65769
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Predictive value of XPG rs2296147T>C polymorphism on clinical outcomes of cancer patients

Predictive value of XPG rs2296147T>C polymorphism on clinical outcomes of cancer patients

https://doi.org/10.18632/oncotarget.11664

Yuhan Wang, Yingying Han, Qiang Weng,  and Zhengrong Yuan
65770-65781
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Involvement of let-7 microRNA for the therapeutic effects of Rhenium-188-embedded liposomal nanoparticles on orthotopic human head and neck cancer model

Involvement of let-7 microRNA for the therapeutic effects of Rhenium-188-embedded liposomal nanoparticles on orthotopic human head and neck cancer model

https://doi.org/10.18632/oncotarget.11666

Liang-Ting Lin, Chun-Yuan Chang, Chih-Hsien Chang, Hsin-Ell Wang, Shih-Hwa Chiou, Ren-Shyan Liu, Te-Wei Lee,  and Yi-Jang Lee
65782-65796
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Stat3 accelerates Myc induced tumor formation while reducing growth rate in a mouse model of breast cancer

Stat3 accelerates Myc induced tumor formation while reducing growth rate in a mouse model of breast cancer

https://doi.org/10.18632/oncotarget.11667

Jing-Ru Jhan,  and Eran R. Andrechek
65797-65807
Abstract  |  PDF  |  HTML  |  Order a Reprint

The small heat shock protein αA-crystallin negatively regulates pancreatic tumorigenesis

The small heat shock protein αA-crystallin negatively regulates pancreatic tumorigenesis

https://doi.org/10.18632/oncotarget.11668

Jifang Liu, Zhongwen Luo, Lan Zhang, Ling Wang, Qian Nie, Zheng-Feng Wang, Zhaoxia Huang, Xiaohui Hu, Lili Gong, Andre-Patrick Arrigo, Xiangcheng Tang, Jia-Wen Xiang, Fangyuan Liu, Mi Deng, Weike Ji, Wenfeng Hu, Ji-Ye Zhu, Baojiang Chen, Julia Bridge, Michael A. Hollingsworth, James Gigantelli, Yizhi Liu, Quan D. Nguyen,  and David Wan-Cheng Li
65808-65824
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Interleukin-32α induces migration of human melanoma cells through downregulation of E-cadherin

Interleukin-32α induces migration of human melanoma cells through downregulation of E-cadherin

https://doi.org/10.18632/oncotarget.11669

Joohyun Lee, Kyung Eun Kim, Soyoung Cheon, Ju Han Song, Younkyung Houh, Tae Sung Kim, Minchan Gil, Kyung Jin Lee, Seonghan Kim, Daejin Kim, Dae Young Hur, Yoolhee Yang, Sa Ik Bang, Hyun Jeong Park,  and Daeho Cho
65825-65836
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis

LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis

https://doi.org/10.18632/oncotarget.11670

Chan Joo Yeom, Lihua Zeng, Yoko Goto, Akiyo Morinibu, Yuxi Zhu, Kazumi Shinomiya, Minoru Kobayashi, Satoshi Itasaka, Michio Yoshimura, Cheol-Goo Hur, Hideaki Kakeya, Ester M. Hammond, Masahiro Hiraoka,  and Hiroshi Harada
65837-65848
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oxysterol-binding protein-related protein 4L promotes cell proliferation by sustaining intracellular Ca2+ homeostasis in cervical carcinoma cell lines

Oxysterol-binding protein-related protein 4L promotes cell proliferation by sustaining intracellular Ca2+ homeostasis in cervical carcinoma cell lines

https://doi.org/10.18632/oncotarget.11671

Ji-Wei Li, Yan-Lin Xiao, Chao-Feng Lai, Ning Lou, Hong-Ling Ma, Bi-Ying Zhu, Wen-Bin Zhong,  and Dao-Guang Yan
65849-65861
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cancer stem cell markers predict a poor prognosis in renal cell carcinoma: a meta-analysis

Cancer stem cell markers predict a poor prognosis in renal cell carcinoma: a meta-analysis

https://doi.org/10.18632/oncotarget.11672

Bo Cheng, Guosheng Yang, Rui Jiang, Yong Cheng, Haifan Yang, Lijun Pei,  and Xiaofu Qiu
65862-65875
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

UBE2C is overexpressed in ESCC tissues and its abrogation attenuates the malignant phenotype of ESCC cell lines

UBE2C is overexpressed in ESCC tissues and its abrogation attenuates the malignant phenotype of ESCC cell lines

https://doi.org/10.18632/oncotarget.11674

Antonio Palumbo Jr., Nathalia Meireles Da Costa, Marco De Martino, Romina Sepe, Simona Pellecchia, Vanessa Paiva Leite de Sousa, Pedro Nicolau Neto, Cleber Dario Kruel, Anke Bergman, Luiz Eurico Nasciutti, Alfredo Fusco,  and Luis Felipe Ribeiro Pinto
65876-65887
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cancer stem cells from human glioblastoma resemble but do not mimic original tumors after in vitro passaging in serum-free media

Cancer stem cells from human glioblastoma resemble but do not mimic original tumors after in vitro passaging in serum-free media

https://doi.org/10.18632/oncotarget.11676

Noemí García-Romero, Carmen González-Tejedo, Josefa Carrión-Navarro, Susana Esteban-Rubio, Gorjana Rackov, Vanessa Rodríguez-Fanjul, Jorge Oliver-De La Cruz, Ricardo Prat-Acín, María Peris-Celda, David Blesa, Laura Ramírez-Jiménez, Pilar Sánchez-Gómez, Rosario Perona, Carmen Escobedo-Lucea, Cristobal Belda-Iniesta,  and Angel Ayuso-Sacido
65888-65901
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

T cell abundance in blood predicts acute organ toxicity in chemoradiotherapy for head and neck cancer

T cell abundance in blood predicts acute organ toxicity in chemoradiotherapy for head and neck cancer

https://doi.org/10.18632/oncotarget.11677

L. Milena Beschel, Martin Leu, Sybille D. Reichardt, Margret Rave-Fränk, Markus A. Schirmer, Christine Stadelmann, Martin Canis, Hendrik A. Wolff,  and Holger M. Reichardt
65902-65915
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic variants of SOX9 contribute to susceptibility of gliomas among Chinese population

Genetic variants of SOX9 contribute to susceptibility of gliomas among Chinese population

https://doi.org/10.18632/oncotarget.11679

Liang Wang, Gang Li, Nan Liu, Zhen Wang, Xiaoshan Xu, Jing Qi, Dongni Ren, Pengxing Zhang, Yongsheng Zhang,  and Yanyang Tu
65916-65922
Abstract  |  PDF  |  HTML  |  Order a Reprint

Direct interaction of Ikaros and Foxp1 modulates expression of the G protein-coupled receptor G2A in B-lymphocytes and acute lymphoblastic leukemia

Direct interaction of Ikaros and Foxp1 modulates expression of the G protein-coupled receptor G2A in B-lymphocytes and acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.11688

Jonathan Bond, Renae Domaschenz, Mónica Roman-Trufero, Pierangela Sabbattini, Isabel Ferreiros-Vidal, Gareth Gerrard, Vahid Asnafi, Elizabeth Macintyre, Matthias Merkenschlager,  and Niall Dillon
65923-65936
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metastatic lymph node ratio can further stratify risk for mortality in medullary thyroid cancer patients: A population-based analysis

Metastatic lymph node ratio can further stratify risk for mortality in medullary thyroid cancer patients: A population-based analysis

https://doi.org/10.18632/oncotarget.11725

Ning Qu, Rong-liang Shi, Zhong-wu Lu, Tian Liao, Duo Wen, Guo-hua Sun, Duan-shu Li,  and Qing-hai Ji
65937-65945
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

c-Fos over-expression promotes radioresistance and predicts poor prognosis in malignant glioma

c-Fos over-expression promotes radioresistance and predicts poor prognosis in malignant glioma

https://doi.org/10.18632/oncotarget.11779

Zhi-Gang Liu, Guanmin Jiang, Jiao Tang, Hui Wang, Guokai Feng, Furong Chen, Ziwei Tu, Guiyun Liu, Yu Zhao, Ming-Jing Peng, Zheng-Wen He, Xiao-Yan Chen, Holly Lindsay, Yun-Fei Xia,  and Xiao-Nan Li
65946-65956
Abstract  |  PDF  |  HTML  |  Order a Reprint

Inhibition of never in mitosis A (NIMA)-related kinase-4 reduces survivin expression and sensitizes cancer cells to TRAIL-induced cell death

Inhibition of never in mitosis A (NIMA)-related kinase-4 reduces survivin expression and sensitizes cancer cells to TRAIL-induced cell death

https://doi.org/10.18632/oncotarget.11781

So Jung Park, Doo Sin Jo, Se-Young Jo, Dong Woon Shin, Sangmi Shim, Yoon Kyung Jo, Ji Hyun Shin, Ye Jin Ha, Seong-Yun Jeong, Jung Jin Hwang, Young Sam Kim, Young-Ah Suh, Jong Wook Chang, Jin Cheon Kim,  and Dong-Hyung Cho
65957-65967
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ibrutinib modifies the function of monocyte/macrophage population in chronic lymphocytic leukemia

Ibrutinib modifies the function of monocyte/macrophage population in chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.11782

Stefania Fiorcari, Rossana Maffei, Valentina Audrito, Silvia Martinelli, Elisa Ten Hacken, Patrizia Zucchini, Giulia Grisendi, Leonardo Potenza, Mario Luppi, Jan A. Burger, Silvia Deaglio,  and Roberto Marasca
65968-65981
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pancreatic stellate cell secreted IL-6 stimulates STAT3 dependent invasiveness of pancreatic intraepithelial neoplasia and cancer cells

Pancreatic stellate cell secreted IL-6 stimulates STAT3 dependent invasiveness of pancreatic intraepithelial neoplasia and cancer cells

https://doi.org/10.18632/oncotarget.11786

Nagaraj S. Nagathihalli, Jason A. Castellanos, Michael N. VanSaun, Xizi Dai, Mahogany Ambrose, Qiaozhi Guo, Yanhua Xiong,  and Nipun B. Merchant
65982-65992
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Analysis of the hormone receptor status of circulating tumor cell subpopulations based on epithelial-mesenchymal transition: a proof-of-principle study on the heterogeneity of circulating tumor cells

Analysis of the hormone receptor status of circulating tumor cell subpopulations based on epithelial-mesenchymal transition: a proof-of-principle study on the heterogeneity of circulating tumor cells

https://doi.org/10.18632/oncotarget.11787

Xiuwen Guan, Fei Ma, Suyan Liu, Shiyang Wu, Rong Xiao, Lifang Yuan, Xiaoying Sun, Zongbi Yi, Huiyi Yang,  and Binghe Xu
65993-66002
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of candidate anti-cancer molecular mechanisms of Compound Kushen Injection using functional genomics

Identification of candidate anti-cancer molecular mechanisms of Compound Kushen Injection using functional genomics

https://doi.org/10.18632/oncotarget.11788

Zhipeng Qu, Jian Cui, Yuka Harata-Lee, Thazin Nwe Aung, Qianjin Feng, Joy M. Raison, Robert Daniel Kortschak,  and David L. Adelson
66003-66019
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ctDNA dynamics: a novel indicator to track resistance in metastatic breast cancer treated with anti-HER2 therapy

ctDNA dynamics: a novel indicator to track resistance in metastatic breast cancer treated with anti-HER2 therapy

https://doi.org/10.18632/oncotarget.11791

Fei Ma, Wenjie Zhu, Yanfang Guan, Ling Yang, Xuefeng Xia, Shanshan Chen, Qiao Li, Xiuwen Guan, Zongbi Yi, Haili Qian, Xin Yi,  and Binghe Xu
66020-66031
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Rig-G is a growth inhibitory factor of lung cancer cells that suppresses STAT3 and NF-κB

Rig-G is a growth inhibitory factor of lung cancer cells that suppresses STAT3 and NF-κB

https://doi.org/10.18632/oncotarget.11797

Dong Li, Junjun Sun, Wenfang Liu, Xuan Wang, Robert Bals, Junlu Wu, Wenqiang Quan, Yiwen Yao, Yu Zhang, Hong Zhou,  and Kaiyin Wu
66032-66050
Abstract  |  PDF  |  HTML  |  Order a Reprint

MiR-155 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells through the activation of PI3K/SGK3/β-catenin signaling pathways

MiR-155 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells through the activation of PI3K/SGK3/β-catenin signaling pathways

https://doi.org/10.18632/oncotarget.11800

Xin Kong, Fengchao Liu,  and Jian Gao
66051-66060
Abstract  |  PDF  |  HTML  |  Order a Reprint

The association analysis of hOGG1 genetic variants and gastric cancer risk in a Chinese population

The association analysis of hOGG1 genetic variants and gastric cancer risk in a Chinese population

https://doi.org/10.18632/oncotarget.11802

Jiafei Lu, Yongmei Yin, Mulong Du, Gaoxiang Ma, Yuqiu Ge, Qiang Zhang, Haiyan Chu, Na Tong, Meilin Wang, Jinrong Qiu,  and Zhengdong Zhang
66061-66068
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Single-cell analyses of transcriptional heterogeneity in squamous cell carcinoma of urinary bladder

Single-cell analyses of transcriptional heterogeneity in squamous cell carcinoma of urinary bladder

https://doi.org/10.18632/oncotarget.11803

Xiaolong Zhang, Meng Zhang, Yong Hou, Liqin Xu, Weidong Li, Zhihui Zou, Chunxiao Liu, Abai Xu,  and Song Wu
66069-66076
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epithelialization of mouse ovarian tumor cells originating in the fallopian tube stroma

Epithelialization of mouse ovarian tumor cells originating in the fallopian tube stroma

https://doi.org/10.18632/oncotarget.11808

Yuanyuan Hua, Pui-Wah Choi, Alexander J. Trachtenberg, Allen C. Ng, Winston P. Kuo, Shu-Kay Ng, Daniela M. Dinulescu, Martin M. Matzuk, Ross S. Berkowitz,  and Shu-Wing Ng
66077-66086
Abstract  |  PDF  |  HTML  |  Order a Reprint

Circadian clock components RORα and Bmal1 mediate the anti-proliferative effect of MLN4924 in osteosarcoma cells

Circadian clock components RORα and Bmal1 mediate the anti-proliferative effect of MLN4924 in osteosarcoma cells

https://doi.org/10.18632/oncotarget.11807

Shuju Zhang, Jiaming Zhang, Zhiyuan Deng, Huadie Liu, Wei Mao, Fang Jiang, Zanxian Xia,  and Jia-Da Li
66087-66099
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SP110 and PMP22 polymorphisms are associated with tuberculosis risk in a Chinese-Tibetan population

SP110 and PMP22 polymorphisms are associated with tuberculosis risk in a Chinese-Tibetan population

https://doi.org/10.18632/oncotarget.11847

Guoxia Ren, Jiangtao You, Xianfeng Gong, Xiucheng Zhang, Lin Zhao, Xianglan Wei, Tianbo Jin,  and Mingwei Chen
66100-66108
Abstract  |  PDF  |  HTML  |  Order a Reprint

Association between cyclin D1 (CCND1) G870A polymorphism and gastric cancer risk: a meta-analysis

Association between cyclin D1 (CCND1) G870A polymorphism and gastric cancer risk: a meta-analysis

https://doi.org/10.18632/oncotarget.11848

Yafei Zhang, Xianling Zeng, Hongwei Lu, Hong Ji, Enfa Zhao,  and Yiming Li
66109-66118
Abstract  |  PDF  |  HTML  |  Order a Reprint

Sialylation transmogrifies human breast and pancreatic cancer cells into 3D multicellular tumor spheroids using cyclic RGD-peptide induced self-assembly

Sialylation transmogrifies human breast and pancreatic cancer cells into 3D multicellular tumor spheroids using cyclic RGD-peptide induced self-assembly

https://doi.org/10.18632/oncotarget.11868

Roman Akasov, Sabah Haq, Fiona Haxho, Vanessa Samuel, Sergey V. Burov, Elena Markvicheva, Ronald J. Neufeld,  and Myron R. Szewczuk
66119-66134
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Neuropeptide Y-mediated sex- and afferent-specific neurotransmissions contribute to sexual dimorphism of baroreflex afferent function

Neuropeptide Y-mediated sex- and afferent-specific neurotransmissions contribute to sexual dimorphism of baroreflex afferent function

https://doi.org/10.18632/oncotarget.11880

Yang Liu, Di Wu, Mei-Yu Qu, Jian-Li He, Mei Yuan, Miao Zhao, Jian-Xin Wang, Jian He, Lu-Qi Wang, Xin-Jing Guo, Meng Zuo, Shu-Yang Zhao, Mei-Na Ma, Jun-Nan Li, Weinian Shou, Guo-Fen Qiao,  and Bai-Yan Li
66135-66148
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Calcification of thyroid nodules increases shear-wave speed (SWS) measurement: using multiple calcification-specific SWS cutoff values outperforms a single uniform cutoff value in diagnosing malignant thyroid nodules

Calcification of thyroid nodules increases shear-wave speed (SWS) measurement: using multiple calcification-specific SWS cutoff values outperforms a single uniform cutoff value in diagnosing malignant thyroid nodules

https://doi.org/10.18632/oncotarget.11710

Bao-Ding Chen, Hui-Xiong Xu, Yi-Feng Zhang, Bo-Ji Liu, Le-Hang Guo, Dan-Dan Li, Chong-Ke Zhao, Xiao-Long Li, Dan Wang,  and Shuang-Shuang Zhao
66149-66159
Abstract  |  PDF  |  HTML  |  Order a Reprint

Adjuvant treatment may benefit patients with high-risk upper rectal cancer: a nomogram and recursive partitioning analysis of 547 patients

Adjuvant treatment may benefit patients with high-risk upper rectal cancer: a nomogram and recursive partitioning analysis of 547 patients

https://doi.org/10.18632/oncotarget.10718

Xin Wang, Jing Jin, Yong Yang, Wen-Yang Liu, Hua Ren, Yan-Ru Feng, Qin Xiao, Ning Li, Lei Deng, Hui Fang, Hao Jing, Ning-Ning Lu, Yu Tang, Jian-Yang Wang, Shu-Lian Wang, Wei-Hu Wang, Yong-Wen Song, Yue-Ping Liu,  and Ye-Xiong Li
66160-66169
Abstract  |  PDF  |  HTML  |  Order a Reprint

Old age at diagnosis increases risk of tumor progression in nasopharyngeal cancer

Old age at diagnosis increases risk of tumor progression in nasopharyngeal cancer

https://doi.org/10.18632/oncotarget.10818

Jing-Dun Xie, Fu Chen, Yao-Xuan He, Xiao-Di Chen, Guo-Ye Zhang, Zhi-Kun Li, Jing Hong, Dan Xie,  and Mu-Yan Cai
66170-66181
Abstract  |  PDF  |  HTML  |  Order a Reprint

Incidence and relative risk of hemorrhagic events associated with ramucirumab in cancer patients: a systematic review and meta-analysis

Incidence and relative risk of hemorrhagic events associated with ramucirumab in cancer patients: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.11097

Rui Tian, Hong Yan, Fei Zhang, Peng Sun, Xucai Zheng, Yi Zhu, Qing Wang,  and Jie He
66182-66191
Abstract  |  PDF  |  HTML  |  Order a Reprint

Primary analysis of a prospective, randomized, single-blinded phase II trial evaluating the HER2 peptide GP2 vaccine in breast cancer patients to prevent recurrence

Primary analysis of a prospective, randomized, single-blinded phase II trial evaluating the HER2 peptide GP2 vaccine in breast cancer patients to prevent recurrence

https://doi.org/10.18632/oncotarget.11751

Elizabeth A. Mittendorf, Alexandros Ardavanis, Jennifer K. Litton, Nathan M. Shumway, Diane F. Hale, James L. Murray, Sonia A. Perez, Sathibalan Ponniah, Constantin N. Baxevanis, Michael Papamichail,  and George E. Peoples
66192-66201
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

Metformin use improves survival of diabetic liver cancer patients: systematic review and meta-analysis

Metformin use improves survival of diabetic liver cancer patients: systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.11033

Shu-Juan Ma, Yi-Xiang Zheng, Peng-Cheng Zhou, Yan-Ni Xiao,  and Hong-Zhuan Tan
66202-66211
Abstract  |  PDF  |  HTML  |  Order a Reprint

Patient-derived xenograft models of colorectal cancer in pre-clinical research: a systematic review

Patient-derived xenograft models of colorectal cancer in pre-clinical research: a systematic review

https://doi.org/10.18632/oncotarget.11184

Kai M. Brown, Aiqun Xue, Anubhav Mittal, Jaswinder S. Samra, Ross Smith,  and Thomas J. Hugh
66212-66225
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The etiologic spectrum of head and neck squamous cell carcinoma in young patients

The etiologic spectrum of head and neck squamous cell carcinoma in young patients

https://doi.org/10.18632/oncotarget.11265

Xin Liu, Xiao-lei Gao, Xin-hua Liang,  and Ya-ling Tang
66226-66238
Abstract  |  PDF  |  HTML  |  Order a Reprint

Adenoid cystic carcinoma: emerging role of translocations and gene fusions

Adenoid cystic carcinoma: emerging role of translocations and gene fusions

https://doi.org/10.18632/oncotarget.11288

Piotr T. Wysocki, Evgeny Izumchenko, Juliet Meir, Patrick K. Ha, David Sidransky,  and Mariana Brait
66239-66254
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeting binding partners of the CBFβ-SMMHC fusion protein for the treatment of inversion 16 acute myeloid leukemia

Targeting binding partners of the CBFβ-SMMHC fusion protein for the treatment of inversion 16 acute myeloid leukemia

https://doi.org/10.18632/oncotarget.11357

Lisa Richter, Yiqian Wang,  and R. Katherine Hyde
66255-66266
Abstract  |  PDF  |  HTML  |  Order a Reprint

PinX1: structure, regulation and its functions in cancer

PinX1: structure, regulation and its functions in cancer

https://doi.org/10.18632/oncotarget.11411

Hai-Long Li, Jun Song, Hong-Mei Yong, Ping-Fu Hou, Yan-Su Chen, Wen-Bo Song, Jin Bai,  and Jun-Nian Zheng
66267-66275
Abstract  |  PDF  |  HTML  |  Order a Reprint

p53, a potential predictor of Helicobacter pylori infection-associated gastric carcinogenesis?

p53, a potential predictor of Helicobacter pylori infection-associated gastric carcinogenesis?

https://doi.org/10.18632/oncotarget.11414

Nianshuang Li, Chuan Xie,  and Nong-Hua Lu
66276-66286
Abstract  |  PDF  |  HTML  |  Order a Reprint

The BCR-ABL/NF-κB signal transduction network: a long lasting relationship in Philadelphia positive Leukemias

The BCR-ABL/NF-κB signal transduction network: a long lasting relationship in Philadelphia positive Leukemias

https://doi.org/10.18632/oncotarget.11507

Giovanna Carrà, Davide Torti, Sabrina Crivellaro, Cristina Panuzzo, Riccardo Taulli, Daniela Cilloni, Angelo Guerrasio, Giuseppe Saglio,  and Alessandro Morotti
66287-66298
Abstract  |  PDF  |  HTML  |  Order a Reprint

Mast cell sarcoma: new cases and literature review

Mast cell sarcoma: new cases and literature review

https://doi.org/10.18632/oncotarget.11812

Jilliana Monnier, Sophie Georgin-Lavialle, Danielle Canioni, Ludovic Lhermitte, Michael Soussan, Michel Arock, Julie Bruneau, Patrice Dubreuil, Christine Bodemer, Marie-Olivia Chandesris, Olivier Lortholary, Olivier Hermine,  and Gandhi Damaj
66299-66309
Abstract  |  PDF  |  HTML  |  Order a Reprint

IκBζ: an emerging player in cancer

IκBζ: an emerging player in cancer

https://doi.org/10.18632/oncotarget.11624

Marie Willems, Nadège Dubois, Lucia Musumeci, Vincent Bours,  and Pierre A. Robe
66310-66322
Abstract  |  PDF  |  HTML  |  Order a Reprint

Corrections

Correction: slanDCs/M-DC8+ cells constitute a distinct subset of dendritic cells in human tonsils

Correction: slanDCs/M-DC8+ cells constitute a distinct subset of dendritic cells in human tonsils

https://doi.org/10.18632/oncotarget.12418

Alessandra Micheletti, Giulia Finotti, Federica Calzetti, Silvia Lonardi, Elisa Zoratti, Mattia Bugatti, Stefania Stefini, William Vermi,  and Marco A. Cassatella
66323-66323
Correction  |  PDF


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