Oncotarget

Vol 7, No 39

September 27, 2016

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About The Cover

The cover for issue 39 of Oncotarget features Figure 6D (Systemic GSI-I decreases growth of NB xenografts and is associated with mitotic catastrophe, decreased proliferation and reduced tumor angiogenesis) from Dorneburg, et al.

Table of Contents

Editorial

Recent developments in vertical transmission of ZIKA virus

Recent developments in vertical transmission of ZIKA virus

https://doi.org/10.18632/oncotarget.11619

Peter S. Silverstein, Nour A. Aljouda,  and Anil Kumar
62797-62798
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Priority Research Papers

γ-secretase inhibitor I inhibits neuroblastoma cells, with NOTCH and the proteasome among its targets

γ-secretase inhibitor I inhibits neuroblastoma cells, with NOTCH and the proteasome among its targets

https://doi.org/10.18632/oncotarget.11715

Carmen Dorneburg, Annika V. Goß, Matthias Fischer, Frederik Roels, Thomas F.E. Barth, Frank Berthold, Roland Kappler, Franz Oswald, Jens T. Siveke, Jan J. Molenaar, Klaus-Michael Debatin,  and Christian Beltinger
62799-62813
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Acquisition of an oncogenic fusion protein serves as an initial driving mutation by inducing aneuploidy and overriding proliferative defects

Acquisition of an oncogenic fusion protein serves as an initial driving mutation by inducing aneuploidy and overriding proliferative defects

https://doi.org/10.18632/oncotarget.11716

Jacob M. Loupe, Patrick J. Miller, Benjamin P. Bonner, Elaine C. Maggi, Jyothi Vijayaraghavan, Jovanny Zabaleta, Christopher M. Taylor, Fern Tsien, Judy S. Crabtree,  and Andrew D. Hollenbach
62814-62835
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Research Papers: Gerotarget (Focus on Aging)

A steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1

A steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1

https://doi.org/10.18632/oncotarget.11229

Kumar K.J. Senthil, Vani M. Gokila, Jeng-Leun Mau, Chin-Chung Lin, Fang-Hua Chu, Chia-Cheng Wei, Vivian Hsiu-Chuan Liao,  and Sheng-Yang Wang
62836-62861
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Blunted dynamics of adenosine A2A receptors is associated with increased susceptibility to Candida albicans infection in the elderly

Blunted dynamics of adenosine A2A receptors is associated with increased susceptibility to Candida albicans infection in the elderly

https://doi.org/10.18632/oncotarget.11760

Lisa Rodrigues, Isabel M. Miranda, Geanne M. Andrade, Marta Mota, Luísa Cortes, Acácio G. Rodrigues, Rodrigo A. Cunha,  and Teresa Gonçalves
62862-62872
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Transfection of the IHH gene into rabbit BMSCs in a simulated microgravity environment promotes chondrogenic differentiation and inhibits cartilage aging

Transfection of the IHH gene into rabbit BMSCs in a simulated microgravity environment promotes chondrogenic differentiation and inhibits cartilage aging

https://doi.org/10.18632/oncotarget.11871

Peng-Cheng Liu, Kuan Liu, Jun-Feng Liu, Kuo Xia, Li-Yang Chen,  and Xing Wu
62873-62885
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Research Papers: Pathology

Long non-coding RNA PVT1 activates hepatic stellate cells through competitively binding microRNA-152

Long non-coding RNA PVT1 activates hepatic stellate cells through competitively binding microRNA-152

https://doi.org/10.18632/oncotarget.11709

Jianjian Zheng, Fujun Yu, Peihong Dong, Limei Wu, Yuan Zhang, Yanwei Hu,  and Lei Zheng
62886-62897
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Research Papers: Immunology

Race-related differences in antibody responses to the inactivated influenza vaccine are linked to distinct pre-vaccination gene expression profiles in blood

Race-related differences in antibody responses to the inactivated influenza vaccine are linked to distinct pre-vaccination gene expression profiles in blood

https://doi.org/10.18632/oncotarget.11704

Raj Kurupati, Andrew Kossenkov, Larissa Haut, Senthil Kannan, Zhiquan Xiang, Yan Li, Susan Doyle, Qin Liu, Kenneth Schmader, Louise Showe,  and Hildegund Ertl
62898-62911
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Research Papers: Autophagy and Cell Death

A potential molecular model for studying apoptosis enhanced by the interaction of BCL-G with JAB1 in swine

A potential molecular model for studying apoptosis enhanced by the interaction of BCL-G with JAB1 in swine

https://doi.org/10.18632/oncotarget.11230

Pengfei Jiang, Xingye Wang, Xiaolin Chen, Yaping Wang, Zhanzhan Kang, Jingna Wang,  and Deli Zhang
62912-62924
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Research Papers

Targeting FXYD2 by cardiac glycosides potently blocks tumor growth in ovarian clear cell carcinoma

Targeting FXYD2 by cardiac glycosides potently blocks tumor growth in ovarian clear cell carcinoma

https://doi.org/10.18632/oncotarget.7497

I-Ling Hsu, Cheng-Yang Chou, Yi-Ying Wu, Jia-En Wu, Chen-Hsien Liang, Yao- Tsung Tsai, Jhen-Yu Ke, Yuh-Ling Chen, Keng-Fu Hsu,  and Tse-Ming Hong
62925-62938
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Systematic analysis of tumour cell-extracellular matrix adhesion identifies independent prognostic factors in breast cancer

Systematic analysis of tumour cell-extracellular matrix adhesion identifies independent prognostic factors in breast cancer

https://doi.org/10.18632/oncotarget.11307

Jason R. Todd, Karen A. Ryall, Simon Vyse, Jocelyn P. Wong, Rachael C. Natrajan, Yinyin Yuan, Aik-Choon Tan,  and Paul H. Huang
62939-62953
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Two common functional catalase gene polymorphisms (rs1001179 and rs794316) and cancer susceptibility: evidence from 14,942 cancer cases and 43,285 controls

Two common functional catalase gene polymorphisms (rs1001179 and rs794316) and cancer susceptibility: evidence from 14,942 cancer cases and 43,285 controls

https://doi.org/10.18632/oncotarget.10617

Kang Liu, Xinghan Liu, Meng Wang, Xijing Wang, Huafeng Kang, Shuai Lin, Pengtao Yang, Cong Dai, Peng Xu, Shanli Li,  and Zhijun Dai
62954-62965
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Clinicopathological and prognostic significance of metastasis-associated in colon cancer-1 (MACC1) overexpression in colorectal cancer: a meta-analysis

Clinicopathological and prognostic significance of metastasis-associated in colon cancer-1 (MACC1) overexpression in colorectal cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.11287

Yang Zhao, Cong Dai, Meng Wang, Huafeng Kang, Shuai Lin, Pengtao Yang, Xinghan Liu, Kang Liu, Peng Xu, Yi Zheng, Shanli Li,  and Zhijun Dai
62966-62975
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The effect of epigenetic silencing and TP53 mutation on the expression of DLL4 in human cancer stem disorder

The effect of epigenetic silencing and TP53 mutation on the expression of DLL4 in human cancer stem disorder

https://doi.org/10.18632/oncotarget.11316

Zhixing Yao,  and Zaki A. Sherif
62976-62988
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Molecular dissection of the valproic acid effects on glioma cells

Molecular dissection of the valproic acid effects on glioma cells

https://doi.org/10.18632/oncotarget.11379

Sabine Hoja, Markus Schulze, Michael Rehli, Martin Proescholdt, Christel Herold-Mende, Peter Hau,  and Markus J. Riemenschneider
62989-63002
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Gene expression signature based screening identifies ribonucleotide reductase as a candidate therapeutic target in Ewing sarcoma

Gene expression signature based screening identifies ribonucleotide reductase as a candidate therapeutic target in Ewing sarcoma

https://doi.org/10.18632/oncotarget.11416

Kelli L. Goss,  and David J. Gordon
63003-63019
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reversibility of glioma stem cells’ phenotypes explains their complex in vitro and in vivo behavior: Discovery of a novel neurosphere-specific enzyme, cGMP-dependent protein kinase 1, using the genomic landscape of human glioma stem cells as a discovery tool

Reversibility of glioma stem cells’ phenotypes explains their complex in vitro and in vivo behavior: Discovery of a novel neurosphere-specific enzyme, cGMP-dependent protein kinase 1, using the genomic landscape of human glioma stem cells as a discovery tool

https://doi.org/10.18632/oncotarget.11589

Thomas J. Wilson, Daniel B. Zamler, Robert Doherty, Maria G. Castro,  and Pedro R. Lowenstein
63020-63041
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Prognostic impact of the expression of Wnt-signaling proteins in cervical carcinoma FIGO stage I-IV treated with radiotherapy or chemoradiotherapy

Prognostic impact of the expression of Wnt-signaling proteins in cervical carcinoma FIGO stage I-IV treated with radiotherapy or chemoradiotherapy

https://doi.org/10.18632/oncotarget.11642

Louise Bohr Mordhorst, Cecilia Ahlin,  and Bengt Sorbe
63042-63053
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Effect of epidermal growth factor receptor gene polymorphisms on prognosis in glioma patients

Effect of epidermal growth factor receptor gene polymorphisms on prognosis in glioma patients

https://doi.org/10.18632/oncotarget.10666

Bin Li, Wenhui Zhao, Jingjie Li, Mengdan Yan, Zhilan Xie, Yuanyuan Zhu, Chao Chen,  and Tianbo Jin
63054-63064
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Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells

Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells

https://doi.org/10.18632/oncotarget.11757

Martuza Sarwar, Julius Semenas, Regina Miftakhova, Athanasios Simoulis, Brian Robinson, Anette Gjörloff Wingren, Nigel P. Mongan, David M. Heery, Heather Johnsson, Per-Anders Abrahamsson, Nishtman Dizeyi, Jun Luo,  and Jenny L. Persson
63065-63081
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Clues toward precision medicine in oral squamous cell carcinoma: utility of next-generation sequencing for the prognostic stratification of high-risk patients harboring neck lymph node extracapsular extension

Clues toward precision medicine in oral squamous cell carcinoma: utility of next-generation sequencing for the prognostic stratification of high-risk patients harboring neck lymph node extracapsular extension

https://doi.org/10.18632/oncotarget.11762

Hung-Ming Wang, Chun-Ta Liao, Tzu-Chen Yen, Shu-Jen Chen, Li-Yu Lee, Chia-Hsun Hsieh, Chien-Yu Lin,  and Shu-Hang Ng
63082-63092
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Visceral fat adipocytes from obese and colorectal cancer subjects exhibit distinct secretory and ω6 polyunsaturated fatty acid profiles and deliver immunosuppressive signals to innate immunity cells

Visceral fat adipocytes from obese and colorectal cancer subjects exhibit distinct secretory and ω6 polyunsaturated fatty acid profiles and deliver immunosuppressive signals to innate immunity cells

https://doi.org/10.18632/oncotarget.10998

Manuela Del Cornò, Massimo D’Archivio, Lucia Conti, Beatrice Scazzocchio, Rosaria Varì, Gloria Donninelli, Barbara Varano, Stefania Giammarioli, Simone De Meo, Gianfranco Silecchia, Francesco Pennestrì, Roberto Persiani, Roberta Masella,  and Sandra Gessani
63093-63105
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Phosphatidylinositide 3-kinase (PI3K) and PI3K-related kinase (PIKK) activity contributes to radioresistance in thyroid carcinomas

Phosphatidylinositide 3-kinase (PI3K) and PI3K-related kinase (PIKK) activity contributes to radioresistance in thyroid carcinomas

https://doi.org/10.18632/oncotarget.11056

Natalie Burrows, Joseph Williams, Brian A Telfer, Julia Resch, Helen R Valentine, Richard J Fitzmaurice, Amanda Eustace, Joely Irlam, Emily J Rowling, Cuong Hoang-Vu, Catharine M West, Georg Brabant,  and Kaye J Williams
63106-63123
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DDA suppresses angiogenesis and tumor growth of colorectal cancer in vivo through decreasing VEGFR2 signaling

DDA suppresses angiogenesis and tumor growth of colorectal cancer in vivo through decreasing VEGFR2 signaling

https://doi.org/10.18632/oncotarget.11152

Shiu-Wen Huang, Jin-Cherng Lien, Sheng-Chu Kuo,  and Tur-Fu Huang
63124-63137
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation extension

Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation extension

https://doi.org/10.18632/oncotarget.11257

Andreia Peixoto, Elisabete Fernandes, Cristiana Gaiteiro, Luís Lima, Rita Azevedo, Janine Soares, Sofia Cotton, Beatriz Parreira, Manuel Neves, Teresina Amaro, Ana Tavares, Filipe Teixeira, Carlos Palmeira, Maria Rangel, André M.N. Silva, Celso A. Reis, Lúcio Lara Santos, Maria José Oliveira,  and José Alexandre Ferreira
63138-63157
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Altered phosphatidylcholines expression in sputum for diagnosis of non-small cell lung cancer

Altered phosphatidylcholines expression in sputum for diagnosis of non-small cell lung cancer

https://doi.org/10.18632/oncotarget.11283

Jianyong Zhang, Jianjun Xu, Haiyan Lu, Jianhua Ding, Dongliang Yu, Penghui Li, Jianwen Xiong, Xingxing Liu, Huanwen Chen,  and Yiping Wei
63158-63165
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Landscape of RNAs in human lumbar disc degeneration

Landscape of RNAs in human lumbar disc degeneration

https://doi.org/10.18632/oncotarget.11334

Ping-Heng Lan, Zhi-Heng Liu, Yan-Jun Pei, Zhi-Gang Wu, Yang Yu, Yong-Feng Yang, Xu Liu, Lu Che, Chi-Jiao Ma, Yan-Ke Xie, Qing-Jie Hu, Zhong-Yuan Wan,  and Hai-Qiang Wang
63166-63176
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Distinct mutation profile and prognostic relevance in patients with hypoplastic myelodysplastic syndromes (h-MDS)

Distinct mutation profile and prognostic relevance in patients with hypoplastic myelodysplastic syndromes (h-MDS)

https://doi.org/10.18632/oncotarget.11050

Chi-Yuan Yao, Hsin-An Hou, Tzung-Yi Lin, Chien-Chin Lin, Wen-Chien Chou, Mei-Hsuan Tseng, Ying-Chieh Chiang, Ming-Chih Liu, Chia-Wen Liu, Yuan-Yeh Kuo, Shang-Ju Wu, Xiu-Wen Liao, Chien-Ting Lin, Bor-Shen Ko, Chien-Yuan Chen, Szu-Chun Hsu, Chi-Cheng Li, Shang-Yi Huang, Ming Yao, Jih-Luh Tang, Woei Tsay, Chieh-Yu Liu,  and Hwei-Fang Tien
63177-63188
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Validation of a network-based strategy for the optimization of combinatorial target selection in breast cancer therapy: siRNA knockdown of network targets in MDA-MB-231 cells as an in vitro model for inhibition of tumor development

Validation of a network-based strategy for the optimization of combinatorial target selection in breast cancer therapy: siRNA knockdown of network targets in MDA-MB-231 cells as an in vitro model for inhibition of tumor development

https://doi.org/10.18632/oncotarget.11055

Tatiana M. Tilli, Nicolas Carels, Jack A. Tuszynski,  and Manijeh Pasdar
63189-63203
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Immunosuppressive effect of bladder cancer on function of dendritic cells involving of Jak2/STAT3 pathway

Immunosuppressive effect of bladder cancer on function of dendritic cells involving of Jak2/STAT3 pathway

https://doi.org/10.18632/oncotarget.11434

Weigang Xiu, Juan Ma, Ting Lei, Man Zhang,  and Shangyan Zhou
63204-63214
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FAM65B controls the proliferation of transformed and primary T cells

FAM65B controls the proliferation of transformed and primary T cells

https://doi.org/10.18632/oncotarget.11438

Jeanne Froehlich, Margaux Versapuech, Laura Megrelis, Quitterie Largeteau, Sylvain Meunier, Corinne Tanchot, Georges Bismuth, Jérôme Delon,  and Marianne Mangeney
63215-63225
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Therapeutic dosages of aspirin counteract the IL-6 induced pro-tumorigenic effects by slowing down the ribosome biogenesis rate

Therapeutic dosages of aspirin counteract the IL-6 induced pro-tumorigenic effects by slowing down the ribosome biogenesis rate

https://doi.org/10.18632/oncotarget.11441

Elisa Brighenti, Ferdinando Antonino Giannone, Francesca Fornari, Carmine Onofrillo, Marzia Govoni, Lorenzo Montanaro, Davide Treré,  and Massimo Derenzini
63226-63241
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The double benefit of Spalax p53: surviving underground hypoxia while defying lung cancer cells in vitro via autophagy and caspase-dependent cell death

The double benefit of Spalax p53: surviving underground hypoxia while defying lung cancer cells in vitro via autophagy and caspase-dependent cell death

https://doi.org/10.18632/oncotarget.11443

Martin Ellis, Orly Stern,  and Osnat Ashur-Fabian
63242-63251
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Target sequencing and CRISPR/Cas editing reveal simultaneous loss of UTX and UTY in urothelial bladder cancer

Target sequencing and CRISPR/Cas editing reveal simultaneous loss of UTX and UTY in urothelial bladder cancer

https://doi.org/10.18632/oncotarget.11207

Jinwoo Ahn, Kwang Hyun Kim, Sanghui Park, Young-Ho Ahn, Ha Young Kim, Hana Yoon, Ji Hyun Lee, Duhee Bang,  and Dong Hyeon Lee
63252-63260
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RORα and RORγ expression inversely correlates with human melanoma progression

RORα and RORγ expression inversely correlates with human melanoma progression

https://doi.org/10.18632/oncotarget.11211

Anna A. Brożyna, Wojciech Jóźwicki, Cezary Skobowiat, Anton Jetten,  and Andrzej T. Slominski
63261-63282
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The accuracy of microRNA-210 in diagnosing lung cancer: a systematic review and meta-analysis

The accuracy of microRNA-210 in diagnosing lung cancer: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.11446

Huqin Yang, Huijuan Wang, Chao Zhang,  and Zhaohui Tong
63283-63293
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Decreased TSPAN1 promotes prostate cancer progression and is a marker for early biochemical recurrence after radical prostatectomy

Decreased TSPAN1 promotes prostate cancer progression and is a marker for early biochemical recurrence after radical prostatectomy

https://doi.org/10.18632/oncotarget.11448

Fan Xu, Yujing Gao, Yanqing Wang, Jiahua Pan, Jianjun Sha, Xiaoguang Shao, Xunlei Kang, Jun Qin, M. James You, Yiran Huang, Baijun Dong,  and Wei Xue
63294-63305
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MetAP1 and MetAP2 drive cell selectivity for a potent anti-cancer agent in synergy, by controlling glutathione redox state

MetAP1 and MetAP2 drive cell selectivity for a potent anti-cancer agent in synergy, by controlling glutathione redox state

https://doi.org/10.18632/oncotarget.11216

Frédéric Frottin, Willy V. Bienvenut, Jérôme Bignon, Eric Jacquet, Alvaro Sebastian Vaca Jacome, Alain Van Dorsselaer, Sarah Cianferani, Christine Carapito, Thierry Meinnel,  and Carmela Giglione
63306-63323
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-β autocrine loop

Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-β autocrine loop

https://doi.org/10.18632/oncotarget.11450

Ye Zeng, Xinghong Yao, Li Chen, Zhiping Yan, Jingxia Liu, Yingying Zhang, Tang Feng, Jiang Wu,  and Xiaoheng Liu
63324-63337
Abstract  |  PDF  |  HTML  |  Order a Reprint

Correlation between body mass index (BMI) and the Gleason score of prostate biopsies in Chinese population

Correlation between body mass index (BMI) and the Gleason score of prostate biopsies in Chinese population

https://doi.org/10.18632/oncotarget.11453

Feng Zhou, Xi Chen, Jinxian Pu, Jun Ouyang, Gang Li, Jigen Ping, Yong Lu, Jianquan Hou,  and Yong Han
63338-63341
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Rab27A mediated by NF-κB promotes the stemness of colon cancer cells via up-regulation of cytokine secretion

Rab27A mediated by NF-κB promotes the stemness of colon cancer cells via up-regulation of cytokine secretion

https://doi.org/10.18632/oncotarget.11454

Feixue Feng, Yinghao Jiang, Huanyu Lu, Xiaozhao Lu, Shan Wang, Lifeng Wang, Mengying Wei, Wei Lu, Zhichao Du, Zichen Ye, Guodong Yang, Fang Yuan, Yanxia Ma, Xiaoying Lei,  and Zifan Lu
63342-63351
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mel-18 negatively regulates stem cell-like properties through downregulation of miR-21 in gastric cancer

Mel-18 negatively regulates stem cell-like properties through downregulation of miR-21 in gastric cancer

https://doi.org/10.18632/oncotarget.11221

Xiao-Feng Wang, Xiao-Wei Zhang, Rui-Xi Hua, Yi-Qun Du, Ming-Zhu Huang, Yong Liu, Yu Fang Cheng,  and Wei-Jian Guo
63352-63361
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Control of translational activation by PIM kinase in activated B-cell diffuse large B-cell lymphoma confers sensitivity to inhibition by PIM447

Control of translational activation by PIM kinase in activated B-cell diffuse large B-cell lymphoma confers sensitivity to inhibition by PIM447

https://doi.org/10.18632/oncotarget.11457

Tara L. Peters, Lingxiao Li, Ana A. Tula-Sanchez, Praechompoo Pongtornpipat,  and Jonathan H. Schatz
63362-63373
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Adrenomedullin blockade suppresses sunitinib-resistant renal cell carcinoma growth by targeting the ERK/MAPK pathway

Adrenomedullin blockade suppresses sunitinib-resistant renal cell carcinoma growth by targeting the ERK/MAPK pathway

https://doi.org/10.18632/oncotarget.11463

Yongqian Gao, Jinyi Li, Na Qiao, Qingsong Meng, Ming Zhang, Xin Wang, Jianghua Jia, Shuwen Yang, Changbao Qu, Wei Li,  and Dongbin Wang
63374-63387
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of tumorigenesis-related mRNAs associated with RNA-binding protein HuR in thyroid cancer cells

Identification of tumorigenesis-related mRNAs associated with RNA-binding protein HuR in thyroid cancer cells

https://doi.org/10.18632/oncotarget.11255

Federica Baldan, Catia Mio, Lorenzo Allegri, Ketty Conzatti, Barbara Toffoletto, Cinzia Puppin, Slobodanka Radovic, Carlo Vascotto, Diego Russo, Carla Di Loreto,  and Giuseppe Damante
63388-63407
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Altered pH gradient at the plasma membrane of osteosarcoma cells is a key mechanism of drug resistance

Altered pH gradient at the plasma membrane of osteosarcoma cells is a key mechanism of drug resistance

https://doi.org/10.18632/oncotarget.11503

Sofia Avnet, Silvia Lemma, Margherita Cortini, Paola Pellegrini, Francesca Perut, Nicoletta Zini, Katsuyuki Kusuzaki, Tokuhiro Chano, Giulia Grisendi, Massimo Dominici, Angelo De Milito,  and Nicola Baldini
63408-63423
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epigenetic changes in localized gastric cancer: the role of RUNX3 in tumor progression and the immune microenvironment

Epigenetic changes in localized gastric cancer: the role of RUNX3 in tumor progression and the immune microenvironment

https://doi.org/10.18632/oncotarget.11520

Marta Jessica Llorca-Cardeñosa, Tania Fleitas, Maider Ibarrola-Villava, María Peña-Chilet, Cristina Mongort, Carolina Martinez-Ciarpaglini, Lara Navarro, Valentina Gambardella, Josefa Castillo, Susana Roselló, Samuel Navarro, Gloria Ribas,  and Andrés Cervantes
63424-63436
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Non-targeted and targeted metabolomics approaches to diagnosing lung cancer and predicting patient prognosis

Non-targeted and targeted metabolomics approaches to diagnosing lung cancer and predicting patient prognosis

https://doi.org/10.18632/oncotarget.11521

Xiaoli Zhang, Xinyue Zhu, Caihong Wang, Haixia Zhang,  and Zhiming Cai
63437-63448
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Silencing of cZNF292 circular RNA suppresses human glioma tube formation via the Wnt/β-catenin signaling pathway

Silencing of cZNF292 circular RNA suppresses human glioma tube formation via the Wnt/β-catenin signaling pathway

https://doi.org/10.18632/oncotarget.11523

Ping Yang, Zhijun Qiu, Yuan Jiang, Lei Dong, Wensheng Yang, Chao Gu, Guang Li,  and Yu Zhu
63449-63455
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Subclones in B-lymphoma cell lines: isogenic models for the study of gene regulation

Subclones in B-lymphoma cell lines: isogenic models for the study of gene regulation

https://doi.org/10.18632/oncotarget.11524

Hilmar Quentmeier, Claudia Pommerenke, Ole Ammerpohl, Robert Geffers, Vivien Hauer, Roderick AF MacLeod, Stefan Nagel, Julia Romani, Emanuela Rosati, Anders Rosén, Cord C Uphoff, Margarete Zaborski,  and Hans G Drexler
63456-63465
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Integrin β1, myosin light chain kinase and myosin IIA are required for activation of PI3K-AKT signaling following MEK inhibition in metastatic triple negative breast cancer

Integrin β1, myosin light chain kinase and myosin IIA are required for activation of PI3K-AKT signaling following MEK inhibition in metastatic triple negative breast cancer

https://doi.org/10.18632/oncotarget.11525

Cheolwon Choi, Junyeob Kwon, Sunyoung Lim,  and David M. Helfman
63466-63487
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Construction and immunological characterization of CD40L or GM-CSF incorporated Hantaan virus like particle

Construction and immunological characterization of CD40L or GM-CSF incorporated Hantaan virus like particle

https://doi.org/10.18632/oncotarget.11329

Qikang Ying, Tiejun Ma, Linfeng Cheng, Xiaoxiao Zhang, Agnieszka D. Truax, Ruixue Ma, Ziyu Liu, Yingfeng Lei, Liang Zhang, Wei Ye, Fanglin Zhang, Zhikai Xu, Lei Shang, Rongrong Liu, Fang Wang,  and Xingan Wu
63488-63503
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Differential IgM expression distinguishes two types of pediatric Burkitt lymphoma in mouse and human

Differential IgM expression distinguishes two types of pediatric Burkitt lymphoma in mouse and human

https://doi.org/10.18632/oncotarget.11531

Anthony B. Eason, Sang-Hoon Sin, Carolina Lin, Blossom Damania, Steven Park, Yuri Fedoriw, Carlos E. Bacchi,  and Dirk P. Dittmer
63504-63513
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Peptidome analysis of human milk from women delivering macrosomic fetuses reveals multiple means of protection for infants

Peptidome analysis of human milk from women delivering macrosomic fetuses reveals multiple means of protection for infants

https://doi.org/10.18632/oncotarget.11532

Xianwei Cui, Yun Li, Lei Yang, Lianghui You, Xing Wang, Chunmei Shi, Chenbo Ji,  and Xirong Guo
63514-63525
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel molecular and clinical staging model to predict survival for patients with esophageal squamous cell carcinoma

A novel molecular and clinical staging model to predict survival for patients with esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.11362

Wei Wang, Zhiwei Wang, Jun Zhao, Min Wei, Xinghua Zhu, Qi He, Tianlong Ling, Xiaoyan Chen, Ziang Cao, Yixin Zhang, Lei Liu,  and Minxin Shi
63526-63536
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer

Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer

https://doi.org/10.18632/oncotarget.11535

Marc Warmoes, Siu W. Lam, Petra van der Groep, Janneke E. Jaspers, Yvonne H.C.M. Smolders, Leon de Boer, Thang V. Pham, Sander R. Piersma, Sven Rottenberg, Epie Boven, Jos Jonkers, Paul J. van Diest,  and Connie R. Jimenez
63537-63548
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Novel synthetic cyclic integrin αvβ3 binding peptide ALOS4: antitumor activity in mouse melanoma models

Novel synthetic cyclic integrin αvβ3 binding peptide ALOS4: antitumor activity in mouse melanoma models

https://doi.org/10.18632/oncotarget.11363

Shiri Yacobovich, Lena Tuchinsky, Michael Kirby, Tetiana Kardash, Oryan Agranyoni, Elimelech Nesher, Boris Redko, Gary Gellerman, Dror Tobi, Katerina Gurova, Igor Koman, Osnat Ashur Fabian,  and Albert Pinhasov
63549-63560
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Long non-coding RNA HoxA-AS3 interacts with EZH2 to regulate lineage commitment of mesenchymal stem cells

Long non-coding RNA HoxA-AS3 interacts with EZH2 to regulate lineage commitment of mesenchymal stem cells

https://doi.org/10.18632/oncotarget.11538

Xin-Xing Zhu, Ya-Wei Yan, Demeng Chen, Chun-Zhi Ai, Xifeng Lu, Shan-Shan Xu, Shan Jiang, Gen-Shen Zhong, Dong-Bao Chen,  and Yi-Zhou Jiang
63561-63570
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HER2 amplification level is not a prognostic factor for HER2-positive breast cancer with trastuzumab-based adjuvant treatment: a systematic review and meta-analysis

HER2 amplification level is not a prognostic factor for HER2-positive breast cancer with trastuzumab-based adjuvant treatment: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.11541

Qian-Qian Xu, Bo Pan, Chang-Jun Wang, Yi-Dong Zhou, Feng Mao, Yan Lin, Jing-Hong Guan, Song-Jie Shen, Xiao-Hui Zhang, Ya-Li Xu, Ying Zhong, Xue-Jing Wang, Yan-Na Zhang,  and Qiang Sun
63571-63582
Abstract  |  PDF  |  HTML  |  Order a Reprint

The ω-3 polyunsaturated fatty acids prevented colitis-associated carcinogenesis through blocking dissociation of β-catenin complex, inhibiting COX-2 through repressing NF-κB, and inducing 15-prostaglandin dehydrogenase

The ω-3 polyunsaturated fatty acids prevented colitis-associated carcinogenesis through blocking dissociation of β-catenin complex, inhibiting COX-2 through repressing NF-κB, and inducing 15-prostaglandin dehydrogenase

https://doi.org/10.18632/oncotarget.11544

Young-Min Han, Migyeung Jeong, Jong-Min Park, Mi-Young Kim, Eun-Jin Go, Ji Young Cha, Kyung Jo Kim,  and Ki Baik Hahm
63583-63595
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ERMP1, a novel potential oncogene involved in UPR and oxidative stress defense, is highly expressed in human cancer

ERMP1, a novel potential oncogene involved in UPR and oxidative stress defense, is highly expressed in human cancer

https://doi.org/10.18632/oncotarget.11550

Alberto Grandi, Alice Santi, Susanna Campagnoli, Matteo Parri, Elisa De Camilli, Chaojun Song, Boquan Jin, Aurelien Lacombe, Serenella Castori-Eppenberger, Paolo Sarmientos, Guido Grandi, Giuseppe Viale, Luigi Terracciano, Paola Chiarugi, Piero Pileri,  and Renata Grifantini
63596-63610
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Numb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy

Numb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy

https://doi.org/10.18632/oncotarget.11553

José M. García-Heredia, Eva M. Verdugo Sivianes, Antonio Lucena-Cacace, Sonia Molina-Pinelo,  and Amancio Carnero
63611-63628
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Protein arginine methyltransferase 1 is a novel regulator of MYCN in neuroblastoma

Protein arginine methyltransferase 1 is a novel regulator of MYCN in neuroblastoma

https://doi.org/10.18632/oncotarget.11556

Allison Eberhardt, Jeanne N. Hansen, Jan Koster, Louis T. Lotta Jr, Simeng Wang, Emmett Livingstone, Kun Qian, Linda J. Valentijn, Yujun George Zheng, Nina F. Schor,  and Xingguo Li
63629-63639
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Common genetic variations in cell cycle and DNA repair pathways associated with pediatric brain tumor susceptibility

Common genetic variations in cell cycle and DNA repair pathways associated with pediatric brain tumor susceptibility

https://doi.org/10.18632/oncotarget.11575

Maral Adel Fahmideh, Catharina Lavebratt, Joachim Schüz, Martin Röösli, Tore Tynes, Michael A. Grotzer, Christoffer Johansen, Claudia E Kuehni, Birgitta Lannering, Michaela Prochazka, Lisbeth S Schmidt,  and Maria Feychting
63640-63650
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

NOD2 up-regulates TLR2-mediated IL-23p19 expression via NF-κB subunit c-Rel in Paneth cell-like cells

NOD2 up-regulates TLR2-mediated IL-23p19 expression via NF-κB subunit c-Rel in Paneth cell-like cells

https://doi.org/10.18632/oncotarget.11467

Gao Tan, Erbo Liang, Kaili Liao, Feihong Deng, Wendi Zhang, Yuqing Chen, Jun Xu,  and Fachao Zhi
63651-63660
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High CLEC-2 expression associates with unfavorable postoperative prognosis of patients with clear cell renal cell carcinoma

High CLEC-2 expression associates with unfavorable postoperative prognosis of patients with clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.11606

Ying Xiong, Li Liu, Yu Xia, Jiajun Wang, Wei Xi, Qi Bai, Yang Qu, Qilai Long, Jiejie Xu,  and Jianming Guo
63661-63668
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Expression of immune checkpoints in T cells of esophageal cancer patients

Expression of immune checkpoints in T cells of esophageal cancer patients

https://doi.org/10.18632/oncotarget.11611

Jinhua Xie, Ji Wang, Shouliang Cheng, Liangfeng Zheng, Feiyue Ji, Lin Yang, Yan Zhang,  and Haoming Ji
63669-63678
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Leucine deprivation inhibits proliferation and induces apoptosis of human breast cancer cells via fatty acid synthase

Leucine deprivation inhibits proliferation and induces apoptosis of human breast cancer cells via fatty acid synthase

https://doi.org/10.18632/oncotarget.11626

Fei Xiao, Chunxia Wang, Hongkun Yin, Junjie Yu, Shanghai Chen, Jing Fang,  and Feifan Guo
63679-63689
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hypoxia inducible factor-1 mediates the expression of the immune checkpoint HLA-G in glioma cells through hypoxia response element located in exon 2

Hypoxia inducible factor-1 mediates the expression of the immune checkpoint HLA-G in glioma cells through hypoxia response element located in exon 2

https://doi.org/10.18632/oncotarget.11628

Layale Yaghi, Isabelle Poras, Renata T. Simoes, Eduardo A. Donadi, Jörg Tost, Antoine Daunay, Bibiana Sgorla de Almeida, Edgardo D. Carosella,  and Philippe Moreau
63690-63707
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

New role of osteopontin in DNA repair and impact on human glioblastoma radiosensitivity

New role of osteopontin in DNA repair and impact on human glioblastoma radiosensitivity

https://doi.org/10.18632/oncotarget.11483

Aurélie Henry, Marie-Julie Nokin, Natacha Leroi, François Lallemand, Jérémy Lambert, Nicolas Goffart, Patrick Roncarati, Elettra Bianchi, Paul Peixoto, Arnaud Blomme, Andrei Turtoi, Olivier Peulen, Yvette Habraken, Félix Scholtes, Philippe Martinive, Philippe Delvenne, Bernard Rogister, Vincent Castronovo,  and Akeila Bellahcène
63708-63721
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Effectiveness of capecitabine with or without docetaxel therapy for the treatment of patients with advanced urothelial carcinoma: a single-institution experience

Effectiveness of capecitabine with or without docetaxel therapy for the treatment of patients with advanced urothelial carcinoma: a single-institution experience

https://doi.org/10.18632/oncotarget.11641

Cong Xue, Xin An, Ye Cao, Tanhuan Chen, Wei Yang, Yingfei Deng, Hui Han, Xiaoyu Teng, Fangjian Zhou,  and Yanxia Shi
63722-63729
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CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo

CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo

https://doi.org/10.18632/oncotarget.11650

Wegwitz Florian, Eva Lenfert, Daniela Gerstel, Lena von Ehrenstein, Julia Einhoff, Geske Schmidt, Matthew Logsdon, Johanna Brandner, Gisa Tiegs, Nicole Beauchemin, Christoph Wagener, Wolfgang Deppert,  and Andrea Kristina Horst
63730-63746
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

[11C]Choline PET/CT in therapy response assessment of a neoadjuvant therapy in locally advanced and high risk prostate cancer before radical prostatectomy

[11C]Choline PET/CT in therapy response assessment of a neoadjuvant therapy in locally advanced and high risk prostate cancer before radical prostatectomy

https://doi.org/10.18632/oncotarget.11653

Sarah M. Schwarzenböck, Anna Knieling, Michael Souvatzoglou, Jens Kurth, Katja Steiger, Matthias Eiber, Irene Esposito, Margitta Retz, Hubert Kübler, Jürgen E. Gschwend, Markus Schwaiger, Bernd J. Krause,  and Mark Thalgott
63747-63757
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Gene status and clinicopathologic characteristics of lung adenocarcinomas with mediastinal lymph node metastasis

Gene status and clinicopathologic characteristics of lung adenocarcinomas with mediastinal lymph node metastasis

https://doi.org/10.18632/oncotarget.11494

Shumeng Zhang, Bing Yan, Jing Zheng, Jing Zhao,  and Jianying Zhou
63758-63766
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RSPOs facilitated HSC activation and promoted hepatic fibrogenesis

RSPOs facilitated HSC activation and promoted hepatic fibrogenesis

https://doi.org/10.18632/oncotarget.11654

Xinguang Yin, Huixing Yi, Linlin Wang, Wanxin Wu, Xiaojun Wu,  and Linghua Yu
63767-63778
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RSL3 and Erastin differentially regulate redox signaling to promote Smac mimetic-induced cell death

RSL3 and Erastin differentially regulate redox signaling to promote Smac mimetic-induced cell death

https://doi.org/10.18632/oncotarget.11687

Jasmin Dächert, Hannah Schoeneberger, Katharina Rohde,  and Simone Fulda
63779-63792
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

NKAIN2 functions as a novel tumor suppressor in prostate cancer

NKAIN2 functions as a novel tumor suppressor in prostate cancer

https://doi.org/10.18632/oncotarget.11690

Xueying Mao, Fei Luo, Lara K. Boyd, Bowei Zhou, Yanling Zhang, Elzbieta Stankiewicz, Jacek Marzec, Natasa Vasiljevic, Yongwei Yu, Ninghan Feng, Jia Xu, Attila Lorincz, Yong Jiang, Claude Chelala, Guoping Ren, Daniel M Berney, Shan-Chao Zhao,  and Yong-Jie Lu
63793-63803
Abstract  |  PDF  |  HTML  |  Order a Reprint

Mycobacterium tuberculosis multistage antigens confer comprehensive protection against pre- and post-exposure infections by driving Th1-type T cell immunity

Mycobacterium tuberculosis multistage antigens confer comprehensive protection against pre- and post-exposure infections by driving Th1-type T cell immunity

https://doi.org/10.18632/oncotarget.11542

Jilei Ma, Maopeng Tian, Xionglin Fan, Qi Yu, Yukai Jing, Weihua Wang, Li Li,  and Zijie Zhou
63804-63815
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Essential role of Na+/Ca2+ exchanger 1 in smoking-induced growth and migration of esophageal squamous cell carcinoma

Essential role of Na+/Ca2+ exchanger 1 in smoking-induced growth and migration of esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.11695

Jiexia Wen, Yan Pang, Tao Zhou, Ximing Qi, Min Zhao, Bin Xuan, Xiangcai Meng, Yunsheng Guo, Qingbin Liu, Huagang Liang, Yang Li, Hui Dong,  and Yimin Wang
63816-63828
Abstract  |  PDF  |  HTML  |  Order a Reprint

Differential effects of histone deacetylase inhibitors on cellular drug transporters and their implications for using epigenetic modifiers in combination chemotherapy

Differential effects of histone deacetylase inhibitors on cellular drug transporters and their implications for using epigenetic modifiers in combination chemotherapy

https://doi.org/10.18632/oncotarget.11561

Benigno C. Valdez, Yang Li, David Murray, Jonathan E. Brammer, Yan Liu, Chitra Hosing, Yago Nieto, Richard E. Champlin,  and Borje S. Andersson
63829-63838
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier

Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier

https://doi.org/10.18632/oncotarget.11696

Ruicheng Yang, Wentong Liu, Ling Miao, Xiaopei Yang, Jiyang Fu, Beibei Dou, Aoling Cai, Xin Zong, Chen Tan, Huanchun Chen,  and Xiangru Wang
63839-63855
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Lipid rafts promote liver cancer cell proliferation and migration by up-regulation of TLR7 expression

Lipid rafts promote liver cancer cell proliferation and migration by up-regulation of TLR7 expression

https://doi.org/10.18632/oncotarget.11697

Yuan Liu, Xiaodong Guo, Liyuan Wu, Mei Yang, Zhiwei Li, Yinjie Gao, Shuhong Liu, Guangde Zhou,  and Jingmin Zhao
63856-63869
Abstract  |  PDF  |  HTML  |  Order a Reprint

Curcumin potentiates antitumor activity of cisplatin in bladder cancer cell lines via ROS-mediated activation of ERK1/2

Curcumin potentiates antitumor activity of cisplatin in bladder cancer cell lines via ROS-mediated activation of ERK1/2

https://doi.org/10.18632/oncotarget.11563

Bong Hee Park, Joung Eun Lim, Hwang Gyun Jeon, Seong Il Seo, Hyun Moo Lee, Han Yong Choi, Seong Soo Jeon,  and Byong Chang Jeong
63870-63886
Abstract  |  PDF  |  HTML  |  Order a Reprint

FAM122A, a new endogenous inhibitor of protein phosphatase 2A

FAM122A, a new endogenous inhibitor of protein phosphatase 2A

https://doi.org/10.18632/oncotarget.11698

Li Fan, Man-Hua Liu, Meng Guo, Chuan-Xi Hu, Zhao-Wen Yan, Jing Chen, Guo-Qiang Chen,  and Ying Huang
63887-63900
Abstract  |  PDF  |  HTML  |  Order a Reprint

Long non-coding RNA MALAT1 acts as a competing endogenous RNA to promote malignant melanoma growth and metastasis by sponging miR-22

Long non-coding RNA MALAT1 acts as a competing endogenous RNA to promote malignant melanoma growth and metastasis by sponging miR-22

https://doi.org/10.18632/oncotarget.11564

Wenkang Luan, Lubo Li, Yan Shi, Xuefeng Bu, Yun Xia, Jinlong Wang, Henry Siaw Djangmah, Xiaohui Liu, Yongping You,  and Bin Xu
63901-63912
Abstract  |  PDF  |  HTML  |  Order a Reprint

Autophagy regulates the survival of cells with chromosomal instability

Autophagy regulates the survival of cells with chromosomal instability

https://doi.org/10.18632/oncotarget.11736

Dawei Liu, Zeeshan Shaukat, Tianqi Xu, Donna Denton, Robert Saint,  and Stephen Gregory
63913-63923
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel application of E1A in combination therapy with EGFR-TKI treatment in breast cancer

A novel application of E1A in combination therapy with EGFR-TKI treatment in breast cancer

https://doi.org/10.18632/oncotarget.11737

Chih-Ming Su, Ting-Yu Chang, Hui-Ping Hsu, Hui-Huang Lai, Jie-Ning Li, Yu-Jhen Lyu, Kuang-Tai Kuo, Ming-Te Huang, Jen-Liang Su,  and Pai-Sheng Chen
63924-63936
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comparative profiling between primary colorectal carcinomas and metastases identifies heterogeneity on drug resistance

Comparative profiling between primary colorectal carcinomas and metastases identifies heterogeneity on drug resistance

https://doi.org/10.18632/oncotarget.11570

Feng Luo, Jinbang Li, Shigang Wu, Xuefang Wu, Meixiang Chen, Xueyun Zhong,  and Kunping Liu
63937-63949
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Transcriptomic and functional pathways analysis of ascorbate-induced cytotoxicity and resistance of Burkitt lymphoma

Transcriptomic and functional pathways analysis of ascorbate-induced cytotoxicity and resistance of Burkitt lymphoma

https://doi.org/10.18632/oncotarget.11740

Zenglin Pei, Xuan Zhang, Chunxia Ji, Song-Mei Liu,  and Jin Wang
63950-63959
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The LSP1 rs3817198 T > C polymorphism contributes to increased breast cancer risk: a meta-analysis of twelve studies

The LSP1 rs3817198 T > C polymorphism contributes to increased breast cancer risk: a meta-analysis of twelve studies

https://doi.org/10.18632/oncotarget.11741

Jianzhou Tang, Hui Li, Jiashun Luo, Hua Mei, Liang Peng,  and Xiaojie Li
63960-63967
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic value of metabolic parameters on preoperative 18F-Fluorodeoxyglucose positron emission tomography/ computed tomography in patients with stage III gastric cancer

Prognostic value of metabolic parameters on preoperative 18F-Fluorodeoxyglucose positron emission tomography/ computed tomography in patients with stage III gastric cancer

https://doi.org/10.18632/oncotarget.11574

Sae Jung Na, Joo Hyun O, Jae Myung Park, Han Hee Lee, Sung Hak Lee, Kyo Young Song, Myung-Gyu Choi,  and Cho Hyun Park
63968-63980
Abstract  |  PDF  |  HTML  |  Order a Reprint

LL202 protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting MAPK/AP-1 signaling

LL202 protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting MAPK/AP-1 signaling

https://doi.org/10.18632/oncotarget.11742

Yuan Gao, Yujie Huang, Yue Zhao, Yang Hu, Zhiyu Li, Qinglong Guo, Kai Zhao,  and Na Lu
63981-63994
Abstract  |  PDF  |  HTML  |  Order a Reprint

Modeling of signaling crosstalk-mediated drug resistance and its implications on drug combination

Modeling of signaling crosstalk-mediated drug resistance and its implications on drug combination

https://doi.org/10.18632/oncotarget.11745

Xiaoqiang Sun, Jiguang Bao, Zhuhong You, Xing Chen,  and Jun Cui
63995-64006
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gata3 restrains B cell proliferation and cooperates with p18INK4c to repress B cell lymphomagenesis

Gata3 restrains B cell proliferation and cooperates with p18INK4c to repress B cell lymphomagenesis

https://doi.org/10.18632/oncotarget.11746

Shiqin Liu, Ho Lam Chan, Feng Bai, Jinshan Ma, Alexandria Scott, David J. Robbins, Anthony J. Capobianco, Ping Zhu,  and Xin-Hai Pei
64007-64020
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Leptin induces osteocalcin expression in ATDC5 cells through activation of the MAPK-ERK1/2 signaling pathway

Leptin induces osteocalcin expression in ATDC5 cells through activation of the MAPK-ERK1/2 signaling pathway

https://doi.org/10.18632/oncotarget.11578

Yingchao Han, Guanghui Xu, Jingjie Zhang, Meijun Yan, Xinhua Li, Bin Ma, Lili Jun, Shan-Jin Wang,  and Jun Tan
64021-64029
Abstract  |  PDF  |  HTML  |  Order a Reprint

Defective CFTR- β-catenin interaction promotes NF-κB nuclear translocation and intestinal inflammation in cystic fibrosis

Defective CFTR- β-catenin interaction promotes NF-κB nuclear translocation and intestinal inflammation in cystic fibrosis

https://doi.org/10.18632/oncotarget.11747

Kaisheng Liu, Xiaohu Zhang, Jie Ting Zhang, Lai Ling Tsang, Xiaohua Jiang,  and Hsiao Chang Chan
64030-64042
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Methylation and expression of PTPN22 in esophageal squamous cell carcinoma

Methylation and expression of PTPN22 in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.11581

Jiaying Deng, Junhua Zhang, Chunyu Wang, Qing Wei, Daizhan Zhou,  and Kuaile Zhao
64043-64052
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Simple and robust diagnosis of early, small and AFP-negative primary hepatic carcinomas: an integrative approach of serum fluorescence and conventional blood tests

Simple and robust diagnosis of early, small and AFP-negative primary hepatic carcinomas: an integrative approach of serum fluorescence and conventional blood tests

https://doi.org/10.18632/oncotarget.11771

Ting Wang, Kun-He Zhang, Piao-Ping Hu, Zeng-Yong Huang, Pan Zhang, Qin-Si Wan, De-Qiang Huang,  and Nong-Hua Lv
64053-64070
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes

Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes

https://doi.org/10.18632/oncotarget.11773

C. Mårten Lindqvist, Anders Lundmark, Jessica Nordlund, Eva Freyhult, Diana Ekman, Jonas Carlsson Almlöf, Amanda Raine, Elin Övernäs, Jonas Abrahamsson, Britt-Marie Frost, Dan Grandér, Mats Heyman, Josefine Palle, Erik Forestier, Gudmar Lönnerholm, Eva C. Berglund,  and Ann-Christine Syvänen
64071-64088
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Phase Ib/II randomized, open-label study of doxorubicin and cyclophosphamide with or without low-dose, short-course sunitinib in the pre-operative treatment of breast cancer

Phase Ib/II randomized, open-label study of doxorubicin and cyclophosphamide with or without low-dose, short-course sunitinib in the pre-operative treatment of breast cancer

https://doi.org/10.18632/oncotarget.11596

Andrea L.A. Wong, Raghav Sundar, Ting-Ting Wang, Thian-C Ng, Bo Zhang, Sing-Huang Tan, Thomas I.P. Soh, Angela S.L. Pang, Chee-Seng Tan, Samuel G.W. Ow, Lingzhi Wang, Jannet Mogro, Jingshan Ho, Anand D. Jeyasekharan, Yiqing Huang, Choon-Hua Thng, Ching-Wan Chan, Mikael Hartman, Philip Iau, Shaik A. Buhari, Boon-Cher Goh,  and Soo-Chin Lee
64089-64099
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-19b suppresses PTPRG to promote breast tumorigenesis

MiR-19b suppresses PTPRG to promote breast tumorigenesis

https://doi.org/10.18632/oncotarget.11799

Minghui Liu, Rong Yang, Uzair Urrehman, Chao Ye, Xin Yan, Shufang Cui, Yeting Hong, Yuanyuan Gu, Yanqing Liu, Chihao Zhao, Liang Yan, Chen-Yu Zhang, Hongwei Liang,  and Xi Chen
64100-64108
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PARP3 controls TGFβ and ROS driven epithelial-to-mesenchymal transition and stemness by stimulating a TG2-Snail-E-cadherin axis

PARP3 controls TGFβ and ROS driven epithelial-to-mesenchymal transition and stemness by stimulating a TG2-Snail-E-cadherin axis

https://doi.org/10.18632/oncotarget.11627

Olga Karicheva, José Manuel Rodriguez-Vargas, Nadège Wadier, Kathline Martin-Hernandez, Romain Vauchelles, Najat Magroun, Agnès Tissier, Valérie Schreiber,  and Françoise Dantzer
64109-64123
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dual role of the integrated stress response in medulloblastoma tumorigenesis

Dual role of the integrated stress response in medulloblastoma tumorigenesis

https://doi.org/10.18632/oncotarget.11873

Sarrabeth Stone, Yeung Ho, Xiting Li, Stephanie Jamison, Heather P. Harding, David Ron,  and Wensheng Lin
64124-64135
Abstract  |  PDF  |  HTML  |  Order a Reprint

Regorafenib (Stivarga) pharmacologically targets epithelial-mesenchymal transition in colorectal cancer

Regorafenib (Stivarga) pharmacologically targets epithelial-mesenchymal transition in colorectal cancer

https://doi.org/10.18632/oncotarget.11636

Li-Ching Fan, Hao-Wei Teng, Chung-Wai Shiau, Wei-Tien Tai, Man-Hsin Hung, Shung-Haur Yang, Jeng-Kai Jiang,  and Kuen-Feng Chen
64136-64147
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comprehensive characterization of lncRNA-mRNA related ceRNA network across 12 major cancers

Comprehensive characterization of lncRNA-mRNA related ceRNA network across 12 major cancers

https://doi.org/10.18632/oncotarget.11637

Yunpeng Zhang, Yanjun Xu, Li Feng, Feng Li, Zeguo Sun, Tan Wu, Xinrui Shi, Jing Li,  and Xia Li
64148-64167
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Coupling CDH17 and CLDN18 markers for comprehensive membrane-targeted detection of human gastric cancer

Coupling CDH17 and CLDN18 markers for comprehensive membrane-targeted detection of human gastric cancer

https://doi.org/10.18632/oncotarget.11638

Keisuke Matsusaka, Tetsuo Ushiku, Masayuki Urabe, Masaki Fukuyo, Hiroyuki Abe, Shumpei Ishikawa, Yasuyuki Seto, Hiroyuki Aburatani, Takao Hamakubo, Atsushi Kaneda,  and Masashi Fukayama
64168-64181
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Biologic behavior and long-term outcomes of breast ductal carcinoma in situ with microinvasion

Biologic behavior and long-term outcomes of breast ductal carcinoma in situ with microinvasion

https://doi.org/10.18632/oncotarget.11639

Yan Fang, Jiayi Wu, Wei Wang, Xiaochun Fei, Yu Zong, Xiaosong Chen, Ou Huang, Jianrong He, Weiguo Chen, Yafen Li, Kunwei Shen,  and Li Zhu
64182-64190
Abstract  |  PDF  |  HTML  |  Order a Reprint

DNA methylation array analysis identifies breast cancer associated RPTOR, MGRN1 and RAPSN hypomethylation in peripheral blood DNA

DNA methylation array analysis identifies breast cancer associated RPTOR, MGRN1 and RAPSN hypomethylation in peripheral blood DNA

https://doi.org/10.18632/oncotarget.11640

Qiuqiong Tang, Tim Holland-Letz, Alla Slynko, Katarina Cuk, Frederik Marme, Sarah Schott, Jörg Heil, Bin Qu, Michael Golatta, Melanie Bewerunge-Hudler, Christian Sutter, Harald Surowy, Barbara Wappenschmidt, Rita Schmutzler, Markus Hoth, Peter Bugert, Claus R. Bartram, Christof Sohn, Andreas Schneeweiss, Rongxi Yang,  and Barbara Burwinkel
64191-64202
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

F5-peptide induces aspermatogenesis by disrupting organization of actin- and microtubule-based cytoskeletons in the testis

F5-peptide induces aspermatogenesis by disrupting organization of actin- and microtubule-based cytoskeletons in the testis

https://doi.org/10.18632/oncotarget.11887

Ying Gao, Dolores D. Mruk, Wing-yee Lui, Will M. Lee,  and C. Yan Cheng
64203-64220
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

AAA-ATPase p97 suppresses apoptotic and autophagy-associated cell death in rheumatoid arthritis synovial fibroblasts

AAA-ATPase p97 suppresses apoptotic and autophagy-associated cell death in rheumatoid arthritis synovial fibroblasts

https://doi.org/10.18632/oncotarget.11890

Masaru Kato, Caroline Ospelt, Christoph Kolling, Tomohiro Shimizu, Michihito Kono, Shinsuke Yasuda, Beat A. Michel, Renate E. Gay, Steffen Gay, Kerstin Klein,  and Tatsuya Atsumi
64221-64232
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circulating serum microRNA-345 correlates with unfavorable pathological response to preoperative chemoradiotherapy in locally advanced rectal cancer

Circulating serum microRNA-345 correlates with unfavorable pathological response to preoperative chemoradiotherapy in locally advanced rectal cancer

https://doi.org/10.18632/oncotarget.11649

Jing Yu, Ning Li, Xin Wang, Hua Ren, Weihu Wang, Shulian Wang, Yongwen Song, Yueping Liu, Yexiong Li, Xuantong Zhou, Aiping Luo, Zhihua Liu,  and Jing Jin
64233-64243
Abstract  |  PDF  |  HTML  |  Order a Reprint

Regulation of matrix metalloproteinases (MMPs) expression and secretion in MDA-MB-231 breast cancer cells by LIM and SH3 protein 1 (LASP1)

Regulation of matrix metalloproteinases (MMPs) expression and secretion in MDA-MB-231 breast cancer cells by LIM and SH3 protein 1 (LASP1)

https://doi.org/10.18632/oncotarget.11720

Marcel Endres, Susanne Kneitz, Martin F. Orth, Ruwan K. Perera, Alma Zernecke,  and Elke Butt
64244-64259
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Loss of Par3 promotes lung adenocarcinoma metastasis through 14-3-3ζ protein

Loss of Par3 promotes lung adenocarcinoma metastasis through 14-3-3ζ protein

https://doi.org/10.18632/oncotarget.11728

Song Tong, Tian Xia, Kai Fan, Ke Jiang, Wei Zhai, Jing-Song Li, Si-Hua Wang,  and Jian-Jun Wang
64260-64273
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activation of the A2B adenosine receptor in B16 melanomas induces CXCL12 expression in FAP-positive tumor stromal cells, enhancing tumor progression

Activation of the A2B adenosine receptor in B16 melanomas induces CXCL12 expression in FAP-positive tumor stromal cells, enhancing tumor progression

https://doi.org/10.18632/oncotarget.11729

Claudia Sorrentino, Lucio Miele, Amalia Porta, Aldo Pinto,  and Silvana Morello
64274-64288
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

DMBA induced mouse mammary tumors display high incidence of activating Pik3caH1047 and loss of function Pten mutations

DMBA induced mouse mammary tumors display high incidence of activating Pik3caH1047 and loss of function Pten mutations

https://doi.org/10.18632/oncotarget.11733

Martín C. Abba, Yi Zhong, Jaeho Lee, Hyunsuk Kil, Yue Lu, Yoko Takata, Melissa S. Simper, Sally Gaddis, Jianjun Shen,  and C. Marcelo Aldaz
64289-64299
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Characterizing the immune microenvironment of malignant peripheral nerve sheath tumor by PD-L1 expression and presence of CD8+ tumor infiltrating lymphocytes

Characterizing the immune microenvironment of malignant peripheral nerve sheath tumor by PD-L1 expression and presence of CD8+ tumor infiltrating lymphocytes

https://doi.org/10.18632/oncotarget.11734

Elizabeth Shurell, Arun S. Singh, Joseph G. Crompton, Sarah Jensen, Yunfeng Li, Sarah Dry, Scott Nelson, Bartosz Chmielowski, Nicholas Bernthal, Noah Federman, Paul Tumeh,  and Fritz C. Eilber
64300-64308
Abstract  |  PDF  |  HTML  |  Order a Reprint

Lipocalin 2 over-expression facilitates progress of castration-resistant prostate cancer via improving androgen receptor transcriptional activity

Lipocalin 2 over-expression facilitates progress of castration-resistant prostate cancer via improving androgen receptor transcriptional activity

https://doi.org/10.18632/oncotarget.11790

Guanxiong Ding, Jianqing Wang, Chenchen Feng, Haowen Jiang, Jianfeng Xu,  and Qiang Ding
64309-64317
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expressions of CD8+TILs, PD-L1 and Foxp3+TILs in stage I NSCLC guiding adjuvant chemotherapy decisions

Expressions of CD8+TILs, PD-L1 and Foxp3+TILs in stage I NSCLC guiding adjuvant chemotherapy decisions

https://doi.org/10.18632/oncotarget.11793

Feifei Teng, Xiangjiao Meng, Xin Wang, Jupeng Yuan, Sujing Liu, Dianbin Mu, Hui Zhu, Li Kong,  and Jinming Yu
64318-64329
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The iron chelator deferasirox induces apoptosis by targeting oncogenic Pyk2/β-catenin signaling in human multiple myeloma

The iron chelator deferasirox induces apoptosis by targeting oncogenic Pyk2/β-catenin signaling in human multiple myeloma

https://doi.org/10.18632/oncotarget.11830

Yusuke Kamihara, Kohichi Takada, Tsutomu Sato, Yutaka Kawano, Kazuyuki Murase, Yohei Arihara, Shohei Kikuchi, Naotaka Hayasaka, Makoto Usami, Satoshi Iyama, Koji Miyanishi, Yasushi Sato, Masayoshi Kobune,  and Junji Kato
64330-64341
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The TAT-RasGAP317-326 anti-cancer peptide can kill in a caspase-, apoptosis-, and necroptosis-independent manner

The TAT-RasGAP317-326 anti-cancer peptide can kill in a caspase-, apoptosis-, and necroptosis-independent manner

https://doi.org/10.18632/oncotarget.11841

Mathieu Heulot, Nadja Chevalier, Julien Puyal, Christiane Margue, Sébastien Michel, Stephanie Kreis, Dagmar Kulms, David Barras, Aimable Nahimana,  and Christian Widmann
64342-64359
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression of PHRF1 attenuates the proliferation and tumorigenicity of non-small cell lung cancer cells

Overexpression of PHRF1 attenuates the proliferation and tumorigenicity of non-small cell lung cancer cells

https://doi.org/10.18632/oncotarget.11842

Yadong Wang, Haiyu Wang, Teng Pan, Li Li, Jiangmin Li,  and Haiyan Yang
64360-64370
Abstract  |  PDF  |  HTML  |  Order a Reprint

Circulating levels of C-reactive protein, interleukin-6 and tumor necrosis factor-α and risk of colorectal adenomas: a meta-analysis

Circulating levels of C-reactive protein, interleukin-6 and tumor necrosis factor-α and risk of colorectal adenomas: a meta-analysis

https://doi.org/10.18632/oncotarget.11853

Xiaoqian Zhang, Shanglong Liu,  and Yanbing Zhou
64371-64379
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Association between gallbladder stone disease and prostate cancer: A nationwide population-based study

Association between gallbladder stone disease and prostate cancer: A nationwide population-based study

https://doi.org/10.18632/oncotarget.9062

Chien-Hua Chen, Cheng-Li Lin,  and Chia-Hung Kao
64380-64389
Abstract  |  PDF  |  HTML  |  Order a Reprint

A phase I study of intratumoral ipilimumab and interleukin-2 in patients with advanced melanoma

A phase I study of intratumoral ipilimumab and interleukin-2 in patients with advanced melanoma

https://doi.org/10.18632/oncotarget.10453

Abhijit Ray, Matthew A. Williams, Stephanie M. Meek, Randy C. Bowen, Kenneth F. Grossmann, Robert H.I. Andtbacka, Tawnya L. Bowles, John R. Hyngstrom, Sancy A. Leachman, Douglas Grossman, Glen M. Bowen, Sheri L. Holmen, Matthew W. VanBrocklin, Gita Suneja,  and Hung T. Khong
64390-64399
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Alternative treatments in advanced hepatocellular carcinoma patients with progressive disease after sorafenib treatment: a prospective multicenter cohort study

Alternative treatments in advanced hepatocellular carcinoma patients with progressive disease after sorafenib treatment: a prospective multicenter cohort study

https://doi.org/10.18632/oncotarget.10794

Masahito Nakano, Masatoshi Tanaka, Ryoko Kuromatsu, Hiroaki Nagamatsu, Manabu Satani, Takashi Niizeki, Shusuke Okamura, Hideki Iwamoto, Shigeo Shimose, Tomotake Shirono, Yu Noda, Hironori Koga, Takuji Torimura,  and Kurume Liver Cancer Study Group of Japan
64400-64409
Abstract  |  PDF  |  HTML  |  Order a Reprint

Responses to crizotinib in patients with ALK-positive lung adenocarcinoma who tested immunohistochemistry (IHC)-positive and fluorescence in situ hybridization (FISH)-negative

Responses to crizotinib in patients with ALK-positive lung adenocarcinoma who tested immunohistochemistry (IHC)-positive and fluorescence in situ hybridization (FISH)-negative

https://doi.org/10.18632/oncotarget.10560

Di Ma, Zheng Wang, Lin Yang, Xinlin Mu, Yan Wang, Xinming Zhao, Junling Li,  and Dongmei Lin
64410-64420
Abstract  |  PDF  |  HTML  |  Order a Reprint

Validation of prognostic scoring and assessment of clinical benefit for patients with bone sarcomas enrolled in phase I clinical trials

Validation of prognostic scoring and assessment of clinical benefit for patients with bone sarcomas enrolled in phase I clinical trials

https://doi.org/10.18632/oncotarget.10910

J. Andrew Livingston, Kenneth R. Hess, Aung Naing, David S. Hong, Shreyaskumar Patel, Robert S. Benjamin, Joseph A. Ludwig, Anthony Conley, Cynthia E. Herzog, Pete Anderson, Funda Meric-Bernstam, Razelle Kurzrock,  and Vivek Subbiah
64421-64430
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

Mechanisms of resistance and sensitivity to anti-HER2 therapies in HER2+ breast cancer

Mechanisms of resistance and sensitivity to anti-HER2 therapies in HER2+ breast cancer

https://doi.org/10.18632/oncotarget.7043

Debora de Melo Gagliato, Denis Leonardo Fontes Jardim, Mario Sergio Pereira Marchesi,  and Gabriel N. Hortobagyi
64431-64446
Abstract  |  PDF  |  HTML  |  Order a Reprint

Molecular mechanisms underlying resistance to androgen deprivation therapy in prostate cancer

Molecular mechanisms underlying resistance to androgen deprivation therapy in prostate cancer

https://doi.org/10.18632/oncotarget.10901

Kristine M. Wadosky,  and Shahriar Koochekpour
64447-64470
Abstract  |  PDF  |  HTML  |  Order a Reprint

Ubc13: the Lys63 ubiquitin chain building machine

Ubc13: the Lys63 ubiquitin chain building machine

https://doi.org/10.18632/oncotarget.10948

Curtis D. Hodge, Leo Spyracopoulos,  and J. N. Mark Glove
64471-64504
Abstract  |  PDF  |  HTML  |  Order a Reprint

Suppressive role of myeloid-derived suppressor cells (MDSCs) in the microenvironment of breast cancer and targeted immunotherapies

Suppressive role of myeloid-derived suppressor cells (MDSCs) in the microenvironment of breast cancer and targeted immunotherapies

https://doi.org/10.18632/oncotarget.11352

Dawei Shou, Liang Wen, Zhenya Song, Jian Yin, Qiming Sun,  and Weihua Gong
64505-64511
Abstract  |  PDF  |  HTML  |  Order a Reprint

The emerging insights into catalytic or non-catalytic roles of TET proteins in tumors and neural development

The emerging insights into catalytic or non-catalytic roles of TET proteins in tumors and neural development

https://doi.org/10.18632/oncotarget.11412

Hao Lian, Wen-Bin Li,  and Wei-Lin Jin
64512-64525
Abstract  |  PDF  |  HTML  |  Order a Reprint

Corrections

Correction: Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgen-independent prostate cancer cells to DNA damage

Correction: Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgen-independent prostate cancer cells to DNA damage

https://doi.org/10.18632/oncotarget.12267

Francesco Marampon, Giovanni Luca Gravina, Xiaoming Ju, Antonella Vetuschi, Roberta Sferra, Mathew C. Casimiro, Simona Pompili, Claudio Festuccia, Alessandro Colapietro, Eugenio Gaudio, Ernesto Di Cesare, Vincenzo Tombolini,  and Richard G. Pestell
64526-64526
Correction  |  PDF


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