Oncotarget

Vol 7, No 38

September 20, 2016

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About The Cover

The cover for issue 38 of Oncotarget features Figure 3C (Loss of Llgl1 induces EGF-dependent mammosphere formation) from Greenwood, et al.

Table of Contents

Priority Research Papers

Llgl1 prevents metaplastic survival driven by epidermal growth factor dependent migration

Llgl1 prevents metaplastic survival driven by epidermal growth factor dependent migration

https://doi.org/10.18632/oncotarget.11320

Erin Greenwood, Sabrina Maisel, David Ebertz, Atlantis Russ, Ritu Pandey,  and Joyce Schroeder
60776-60792
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Fusion between cancer cells and macrophages occurs in a murine model of spontaneous neu+ breast cancer without increasing its metastatic potential

Fusion between cancer cells and macrophages occurs in a murine model of spontaneous neu+ breast cancer without increasing its metastatic potential

https://doi.org/10.18632/oncotarget.11508

Michela Lizier, Achille Anselmo, Stefano Mantero, Francesca Ficara, Marianna Paulis, Paolo Vezzoni, Franco Lucchini,  and Giovanni Pacchiana
60793-60806
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Phenotypic consequences of somatic mutations in the ataxia-telangiectasia mutated gene in non-small cell lung cancer

Phenotypic consequences of somatic mutations in the ataxia-telangiectasia mutated gene in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.11845

Anika Maria Weber, Neele Drobnitzky, Aoife Maire Devery, Sivan Mili Bokobza, Richard A. Adams, Timothy S. Maughan,  and Anderson Joseph Ryan
60807-60822
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Research Papers: Gerotarget (Focus on Aging)

Piperine induces autophagy by enhancing protein phosphotase 2A activity in a rotenone-induced Parkinson’s disease model

Piperine induces autophagy by enhancing protein phosphotase 2A activity in a rotenone-induced Parkinson’s disease model

https://doi.org/10.18632/oncotarget.11661

Jia Liu, Min Chen, Xue Wang, Yi Wang, Chunli Duan, Ge Gao, Lingling Lu, Xia Wu, Xiaomin Wang,  and Hui Yang
60823-60843
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The rate of change in declining steroid hormones: a new parameter of healthy aging in men?

The rate of change in declining steroid hormones: a new parameter of healthy aging in men?

https://doi.org/10.18632/oncotarget.11752

Andreas Walther, Michel Philipp, Niclà Lozza,  and Ulrike Ehlert
60844-60857
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Research Papers: Immunology

Cytokines can counteract the inhibitory effect of MEK-i on NK-cell function

Cytokines can counteract the inhibitory effect of MEK-i on NK-cell function

https://doi.org/10.18632/oncotarget.11504

Claudia Manzini, Roberta Venè, Irene Cossu, Marina Gualco, Simonetta Zupo, Mariella Dono, Francesco Spagnolo, Paola Queirolo, Lorenzo Moretta, Maria Cristina Mingari,  and Gabriella Pietra
60858-60871
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AIRE polymorphism, melanoma antigen-specific T cell immunity, and susceptibility to melanoma

AIRE polymorphism, melanoma antigen-specific T cell immunity, and susceptibility to melanoma

https://doi.org/10.18632/oncotarget.11506

Giuseppina Conteduca, Daniela Fenoglio, Alessia Parodi, Florinda Battaglia, Francesca Kalli, Simone Negrini, Samuele Tardito, Francesca Ferrera, Annalisa Salis, Enrico Millo, Giuseppe Pasquale, Giusi Barra, Gianluca Damonte, Francesco Indiveri, Soldano Ferrone,  and Gilberto Filaci
60872-60884
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Deficient for endoplasmic reticulum calcium sensors Stim1 and Stim2 affects aberrant antibody affinity maturation in B cells

Deficient for endoplasmic reticulum calcium sensors Stim1 and Stim2 affects aberrant antibody affinity maturation in B cells

https://doi.org/10.18632/oncotarget.11659

Xuhua Mao, Jianfeng Zhang, Yue Han, Chao Luan, Yu Hu, Zhiming Hao,  and Min Chen
60885-60895
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Activation and selective IL-17 response of human Vγ9Vδ2 T lymphocytes by TLR-activated plasmacytoid dendritic cells

Activation and selective IL-17 response of human Vγ9Vδ2 T lymphocytes by TLR-activated plasmacytoid dendritic cells

https://doi.org/10.18632/oncotarget.11755

Elena Lo Presti, Nadia Caccamo, Valentina Orlando, Francesco Dieli,  and Serena Meraviglia
60896-60905
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P2Y6 contributes to ovalbumin-induced allergic asthma by enhancing mast cell function in mice

P2Y6 contributes to ovalbumin-induced allergic asthma by enhancing mast cell function in mice

https://doi.org/10.18632/oncotarget.11758

Jue-ping Shi, Shao-ying Wang, Li-li Chen, Xiao-yu Zhang, Yi-han Zhao, Bing Du, Wen-zheng Jiang, Min Qian,  and Hua Ren
60906-60918
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Research Papers: Neuroscience

Role of Jnk1 in development of neural precursors revealed by iPSC modeling

Role of Jnk1 in development of neural precursors revealed by iPSC modeling

https://doi.org/10.18632/oncotarget.11377

Qian Zhang, Jian Mao, Xiaoxi Zhang, Haifeng Fu, Siyuan Xia, Zhinan Yin,  and Lin Liu
60919-60928
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Research Papers

Fine-mapping markers of lung cancer susceptibility in a sub-region of chromosome 19q13.3 among Chinese

Fine-mapping markers of lung cancer susceptibility in a sub-region of chromosome 19q13.3 among Chinese

https://doi.org/10.18632/oncotarget.9279

Jiaoyang Yin, Huiwen Wang, Ulla Vogel, Chunhong Wang, Yegang Ma, Wei Hou, Ying Zhang, Li Guo,  and Xinxin Li
60929-60939
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Repair of UVB-induced DNA damage is reduced in melanoma due to low XPC and global genome repair

Repair of UVB-induced DNA damage is reduced in melanoma due to low XPC and global genome repair

https://doi.org/10.18632/oncotarget.10902

Timothy Budden, Ryan J. Davey, Ricardo E. Vilain, Katie A. Ashton, Stephen G. Braye, Natalie J. Beveridge,  and Nikola A. Bowden
60940-60953
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PPARγ agonists promote differentiation of cancer stem cells by restraining YAP transcriptional activity

PPARγ agonists promote differentiation of cancer stem cells by restraining YAP transcriptional activity

https://doi.org/10.18632/oncotarget.11273

Upal Basu-Roy, Eugenia Han, Kirk Rattanakorn, Abhilash Gadi, Narendra Verma, Giulia Maurizi, Preethi H. Gunaratne, Cristian Coarfa, Oran D. Kennedy, Michael J. Garabedian, Claudio Basilico,  and Alka Mansukhani
60954-60970
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Vhl deletion in renal epithelia causes HIF-1α-dependent, HIF-2α-independent angiogenesis and constitutive diuresis

Vhl deletion in renal epithelia causes HIF-1α-dependent, HIF-2α-independent angiogenesis and constitutive diuresis

https://doi.org/10.18632/oncotarget.11275

Désirée Schönenberger, Michal Rajski, Sabine Harlander,  and Ian J. Frew
60971-60985
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Role of mir-15a/16-1 in early B cell development in a mouse model of chronic lymphocytic leukemia

Role of mir-15a/16-1 in early B cell development in a mouse model of chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.11290

Chingiz Underbayev, Siddha Kasar, William Ruezinsky, Heba Degheidy, Joel Solomon Schneider, Gerald Marti, Steven R. Bauer, Diego Fraidenraich, Marilyn M. Lightfoote, Vijay Parashar, Elizabeth Raveche,  and Mona Batish
60986-60999
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer

Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer

https://doi.org/10.18632/oncotarget.11314

Dubravka Škalamera, Mareike Dahmer-Heath, Alexander J. Stevenson, Cletus Pinto, Esha T. Shah, Sheena M. Daignault, Nur Akmarina B.M. Said, Melissa Davis, Nikolas K. Haass, Elizabeth D. Williams, Brett G. Hollier, Erik W. Thompson, Brian Gabrielli,  and Thomas J. Gonda
61000-61020
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The bile acid receptor GPBAR1 (TGR5) is expressed in human gastric cancers and promotes epithelial-mesenchymal transition in gastric cancer cell lines

The bile acid receptor GPBAR1 (TGR5) is expressed in human gastric cancers and promotes epithelial-mesenchymal transition in gastric cancer cell lines

https://doi.org/10.18632/oncotarget.10477

Adriana Carino, Luigina Graziosi, Claudio D’Amore, Sabrina Cipriani, Silvia Marchianò, Elisabetta Marino, Angela Zampella, Mario Rende, Paolo Mosci, Eleonora Distrutti, Annibale Donini,  and Stefano Fiorucci
61021-61035
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling

NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling

https://doi.org/10.18632/oncotarget.11062

Jianchao Zhang, Ximing Shao, Haiyan Sun, Ke Liu, Zhihao Ding, Juntao Chen, Lijing Fang, Wu Su, Yang Hong, Huashun Li,  and Hongchang Li
61036-61053
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RWCFusion: identifying phenotype-specific cancer driver gene fusions based on fusion pair random walk scoring method

RWCFusion: identifying phenotype-specific cancer driver gene fusions based on fusion pair random walk scoring method

https://doi.org/10.18632/oncotarget.11064

Jianmei Zhao, Xuecang Li, Qianlan Yao, Meng Li, Jian Zhang, Bo Ai, Wei Liu, Qiuyu Wang, Chenchen Feng, Yuejuan Liu, Xuefeng Bai, Chao Song, Shang Li, Enmin Li, Liyan Xu,  and Chunquan Li
61054-61068
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Exogenous IL-33 overcomes T cell tolerance in murine acute myeloid leukemia

Exogenous IL-33 overcomes T cell tolerance in murine acute myeloid leukemia

https://doi.org/10.18632/oncotarget.11179

Lei Qin, Donye Dominguez, Siqi Chen, Jie Fan, Alan Long, Minghui Zhang, Deyu Fang, Yi Zhang, Timothy M. Kuzel,  and Bin Zhang
61069-61080
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Novel B55α-PP2A mutations in AML promote AKT T308 phosphorylation and sensitivity to AKT inhibitor-induced growth arrest

Novel B55α-PP2A mutations in AML promote AKT T308 phosphorylation and sensitivity to AKT inhibitor-induced growth arrest

https://doi.org/10.18632/oncotarget.11209

Geoffrey Shouse, Rosalia de Necochea-Campion, Saied Mirshahidi, Xuan Liu,  and Chien-Shing Chen
61081-61092
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity

Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity

https://doi.org/10.18632/oncotarget.11212

Ning Cao, Xiaofang Ma, Zhenzhen Guo, Yaqiu Zheng, Shengnan Geng, Mingjing Meng, Zhenhua Du, Haihong Lin, Yongjian Duan,  and Gangjun Du
61093-61106
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Interleukin-6 increases matrix metalloproteinase-14 (MMP-14) levels via down-regulation of p53 to drive cancer progression

Interleukin-6 increases matrix metalloproteinase-14 (MMP-14) levels via down-regulation of p53 to drive cancer progression

https://doi.org/10.18632/oncotarget.11243

Jillian M. Cathcart, Anna Banach, Alice Liu, Jun Chen, Michael Goligorsky,  and Jian Cao
61107-61120
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Lysosomal acid lipase in mesenchymal stem cell stimulation of tumor growth and metastasis

Lysosomal acid lipase in mesenchymal stem cell stimulation of tumor growth and metastasis

https://doi.org/10.18632/oncotarget.11244

Ting Zhao, Cong Yan,  and Hong Du
61121-61135
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The histone methyltransferase G9a as a therapeutic target to override gemcitabine resistance in pancreatic cancer

The histone methyltransferase G9a as a therapeutic target to override gemcitabine resistance in pancreatic cancer

https://doi.org/10.18632/oncotarget.11256

Mei-Ren Pan, Ming-Chuan Hsu, Chi-Wen Luo, Li-Tzong Chen, Yan-Shen Shan,  and Wen-Chun Hung
61136-61151
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Oncogenic effects of urotensin-II in cells lacking tuberous sclerosis complex-2

Oncogenic effects of urotensin-II in cells lacking tuberous sclerosis complex-2

https://doi.org/10.18632/oncotarget.10748

Alexander A. Goldberg, Kwang-Bo Joung, Asma Mansuri, Yujin Kang, Raquel Echavarria, Ljiljana Nikolajev, Yang Sun, Jane J. Yu, Stephane A. Laporte, Adel Schwertani,  and Arnold S. Kristof
61152-61165
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-4653-3p and its target gene FRS2 are prognostic biomarkers for hormone receptor positive breast cancer patients receiving tamoxifen as adjuvant endocrine therapy

MiR-4653-3p and its target gene FRS2 are prognostic biomarkers for hormone receptor positive breast cancer patients receiving tamoxifen as adjuvant endocrine therapy

https://doi.org/10.18632/oncotarget.11278

XiaoRong Zhong, GuiQin Xie, Zhang Zhang, Zhu Wang, Yu Wang, YanPing Wang, Yan Qiu, Li Li, Hong Bu, JiaYuan Li,  and Hong Zheng
61166-61182
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IL-13/STAT6 signaling plays a critical role in the epithelial-mesenchymal transition of colorectal cancer cells

IL-13/STAT6 signaling plays a critical role in the epithelial-mesenchymal transition of colorectal cancer cells

https://doi.org/10.18632/oncotarget.11282

Hui Cao, Jing Zhang, Hong Liu, Ledong Wan, Honghe Zhang, Qiong Huang, Enping Xu,  and Maode Lai
61183-61198
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comprehensive N-glycan profiles of hepatocellular carcinoma reveal association of fucosylation with tumor progression and regulation of FUT8 by microRNAs

Comprehensive N-glycan profiles of hepatocellular carcinoma reveal association of fucosylation with tumor progression and regulation of FUT8 by microRNAs

https://doi.org/10.18632/oncotarget.11284

Lei Cheng, Shuhang Gao, Xiaobo Song, Weijie Dong, Huimin Zhou, Lifen Zhao,  and Li Jia
61199-61214
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Identification and functional analysis of long non-coding RNAs in human and mouse early embryos based on single-cell transcriptome data

Identification and functional analysis of long non-coding RNAs in human and mouse early embryos based on single-cell transcriptome data

https://doi.org/10.18632/oncotarget.11304

Jia-jun Qiu, Zhao-rui Ren,  and Jing-bin Yan
61215-61228
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells

Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells

https://doi.org/10.18632/oncotarget.11310

Remya Raja, Nandini A. Sahasrabuddhe, Aneesha Radhakrishnan, Nazia Syed, Hitendra S. Solanki, Vinuth N. Puttamallesh, Sai A. Balaji, Vishalakshi Nanjappa, Keshava K. Datta, Niraj Babu, Santosh Renuse, Arun H. Patil, Evgeny Izumchenko, T.S. Keshava Prasad, Xiaofei Chang, Annapoorni Rangarajan, David Sidransky, Akhilesh Pandey, Harsha Gowda,  and Aditi Chatterjee
61229-61245
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Overcoming chemoresistance in prostate cancer with Chinese medicine Tripterygium wilfordii via multiple mechanisms

Overcoming chemoresistance in prostate cancer with Chinese medicine Tripterygium wilfordii via multiple mechanisms

https://doi.org/10.18632/oncotarget.10868

Zhijun Wang, Ranadheer Ravula, Leming Shi, Yunjie Song, Steven Yeung, Mandy Liu, Bernard Lau, Jijun Hao, Jeffrey Wang, Christopher Wai Kei Lam, Moses Sing Sum Chow,  and Ying Huang
61246-61261
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TGF-β1 stimulates migration of type II endometrial cancer cells by down-regulating PTEN via activation of SMAD and ERK1/2 signaling pathways

TGF-β1 stimulates migration of type II endometrial cancer cells by down-regulating PTEN via activation of SMAD and ERK1/2 signaling pathways

https://doi.org/10.18632/oncotarget.11311

Siyuan Xiong, Jung-Chien Cheng, Christian Klausen, Jianfang Zhao,  and Peter C.K. Leung
61262-61272
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ADAMTS6 suppresses tumor progression via the ERK signaling pathway and serves as a prognostic marker in human breast cancer

ADAMTS6 suppresses tumor progression via the ERK signaling pathway and serves as a prognostic marker in human breast cancer

https://doi.org/10.18632/oncotarget.11341

Yuxin Xie, Qiheng Gou, Keqi Xie, Zhu Wang, Yanping Wang,  and Hong Zheng
61273-61283
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A greater number of dissected lymph nodes is associated with more favorable outcomes in bladder cancer treated by radical cystectomy: a meta-analysis

A greater number of dissected lymph nodes is associated with more favorable outcomes in bladder cancer treated by radical cystectomy: a meta-analysis

https://doi.org/10.18632/oncotarget.11343

Fei Li, Xuwei Hong, Lina Hou, Fengsheng Lin, Pengliang Chen, Shiyu Pang, Yuejun Du, He Huang,  and Wanlong Tan
61284-61294
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Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide

Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide

https://doi.org/10.18632/oncotarget.10973

Birgit C. Weyhenmeyer, Janis Noonan, Maximilian L. Würstle, Frank A. Lincoln, Grainne Johnston, Markus Rehm,  and Brona M. Murphy
61295-61311
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-450b-5p induced by oncogenic KRAS is required for colorectal cancer progression

miR-450b-5p induced by oncogenic KRAS is required for colorectal cancer progression

https://doi.org/10.18632/oncotarget.11016

Ya-Ping Ye, Ping Wu, Chun-cai Gu, Dan-ling Deng, Hong-Li Jiao, Ting-Ting Li, Shu-Yang Wang, Yong-Xia Wang, Zhi-Yuan Xiao, Wen-ting Wei, Yan-Ru Chen, Jun-Feng Qiu, Run-Wei Yang, Jie Lin, Li Liang, Wen-Ting Liao,  and Yan-Qing Ding
61312-61324
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dynamics of PBMC gene expression in hepatitis C virus genotype 1-infected patients during combined peginterferon/ribavirin therapy

Dynamics of PBMC gene expression in hepatitis C virus genotype 1-infected patients during combined peginterferon/ribavirin therapy

https://doi.org/10.18632/oncotarget.11348

Ming-Ying Lu, Ching-I Huang, Ming-Yen Hsieh, Tusty-Juan Hsieh, Edward Hsi, Pei-Chien Tsai, Yi-Shan Tsai, Ching-Chih Lin, Meng-Hsuan Hsieh, Po-Cheng Liang, Yi-Hung Lin, Nai-Jen Hou, Ming-Lun Yeh, Chung-Feng Huang, Zu-Yau Lin, Shinn-Cherng Chen, Jee-Fu Huang, Wan-Long Chuang, Chia-Yen Dai,  and Ming-Lung Yu
61325-61335
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Role of the immune system in the peritoneal tumor spread of high grade serous ovarian cancer

Role of the immune system in the peritoneal tumor spread of high grade serous ovarian cancer

https://doi.org/10.18632/oncotarget.11038

Katharina Auer, Anna Bachmayr-Heyda, Nyamdelger Sukhbaatar, Stefanie Aust, Klaus G. Schmetterer, Samuel M. Meier, Christopher Gerner, Christoph Grimm, Reinhard Horvat,  and Dietmar Pils
61336-61354
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Up-regulation of miR-187 modulates the advances of oral carcinoma by targeting BARX2 tumor suppressor

Up-regulation of miR-187 modulates the advances of oral carcinoma by targeting BARX2 tumor suppressor

https://doi.org/10.18632/oncotarget.11349

Shu-Chun Lin, Shou-Yen Kao, Jennifer Chen-Yu Chang, Ying-Chieh Liu, En-Hao Yu, Ssu-Hsueh Tseng, Chung-Ji Liu,  and Kuo-Wei Chang
61355-61365
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Role of high expression levels of STK39 in the growth, migration and invasion of non-small cell type lung cancer cells

Role of high expression levels of STK39 in the growth, migration and invasion of non-small cell type lung cancer cells

https://doi.org/10.18632/oncotarget.11351

Zhao Li, Wenzhuo Zhu, Liwen Xiong, Xiaobo Yu, Xi Chen,  and Qiang Lin
61366-61377
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nomogram for preoperative estimation of long-term survival of patients who underwent curative resection with hepatocellular carcinoma beyond Barcelona clinic liver cancer stage A1

Nomogram for preoperative estimation of long-term survival of patients who underwent curative resection with hepatocellular carcinoma beyond Barcelona clinic liver cancer stage A1

https://doi.org/10.18632/oncotarget.11358

Dan-Yun Ruan, Ze-Xiao Lin, Tian-Tian Wang, Hui Zhao, Dong-Hao Wu, Jie Chen, Min Dong, Qu Lin, Xiang-Yuan Wu,  and Yang Li
61378-61389
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Elevated O-GlcNAcylation promotes gastric cancer cells proliferation by modulating cell cycle related proteins and ERK 1/2 signaling

Elevated O-GlcNAcylation promotes gastric cancer cells proliferation by modulating cell cycle related proteins and ERK 1/2 signaling

https://doi.org/10.18632/oncotarget.11359

Mingzuo Jiang, Zhaoyan Qiu, Song Zhang, Xing Fan, Xiqiang Cai, Bing Xu, Xiaowei Li, Jinfeng Zhou, Xiangyuan Zhang, Yi Chu, Weijie Wang, Jie Liang, Tamas Horvath, Xiaoyong Yang, Kaichun Wu, Yongzhan Nie,  and Daiming Fan
61390-61402
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Sulforaphane-induced apoptosis involves the type 1 IP3 receptor

Sulforaphane-induced apoptosis involves the type 1 IP3 receptor

https://doi.org/10.18632/oncotarget.8968

Sona Hudecova, Jana Markova, Veronika Simko, Lucia Csaderova, Tibor Stracina, Marta Sirova, Michaela Fojtu, Eliska Svastova, Paulina Gronesova, Michal Pastorek, Marie Novakova, Dana Cholujova, Juraj Kopacek, Silvia Pastorekova, Jan Sedlak,  and Olga Krizanova
61403-61418
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Methotrexate therapy of T-cell large granular lymphocytic leukemia impact of STAT3 mutation

Methotrexate therapy of T-cell large granular lymphocytic leukemia impact of STAT3 mutation

https://doi.org/10.18632/oncotarget.11360

Zhi-Yuan Qiu, Lei Fan, Rong Wang, Robert Peter Gale, Hua-Jin Liang, Man Wang, Li Wang, Yu-Jie Wu, Chun Qiao, Yao-Yu Chen, Wei Xu, Jun Qian,  and Jian-Yong Li
61419-61425
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Identification and characterization of the intercellular adhesion molecule-2 gene as a novel p53 target

Identification and characterization of the intercellular adhesion molecule-2 gene as a novel p53 target

https://doi.org/10.18632/oncotarget.11366

Yasushi Sasaki, Miyuki Tamura, Kousuke Takeda, Kazuhiro Ogi, Takafumi Nakagaki, Ryota Koyama, Masashi Idogawa, Hiroyoshi Hiratsuka,  and Takashi Tokino
61426-61437
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Inhibition of interleukin-1β-induced endothelial tissue factor expression by the synthetic cannabinoid WIN 55,212-2

Inhibition of interleukin-1β-induced endothelial tissue factor expression by the synthetic cannabinoid WIN 55,212-2

https://doi.org/10.18632/oncotarget.11367

Antje Scholl, Igor Ivanov,  and Burkhard Hinz
61438-61457
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Ets2 knockdown inhibits tumorigenesis in esophageal squamous cell carcinoma in vivo and in vitro

Ets2 knockdown inhibits tumorigenesis in esophageal squamous cell carcinoma in vivo and in vitro

https://doi.org/10.18632/oncotarget.11369

Qinghua Li, Lu Yang, Kang Han, Liqiang Zhu, Yanting Zhang, Shanshan Ma, Kun Zhang, Bo Yang,  and Fangxia Guan
61458-61468
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer

Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer

https://doi.org/10.18632/oncotarget.11129

Keisuke Yamamoto, Keisuke Tateishi, Yotaro Kudo, Mayumi Hoshikawa, Mariko Tanaka, Takuma Nakatsuka, Hiroaki Fujiwara, Koji Miyabayashi, Ryota Takahashi, Yasuo Tanaka, Hideaki Ijichi, Yousuke Nakai, Hiroyuki Isayama, Yasuyuki Morishita, Taku Aoki, Yoshihiro Sakamoto, Kiyoshi Hasegawa, Norihiro Kokudo, Masashi Fukayama,  and Kazuhiko Koike
61469-61484
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Deregulated FADD expression and phosphorylation in T-cell lymphoblastic lymphoma

Deregulated FADD expression and phosphorylation in T-cell lymphoblastic lymphoma

https://doi.org/10.18632/oncotarget.11370

José L. Marín-Rubio, María C. de Arriba, María A. Cobos-Fernández, Laura González-Sánchez, Inmaculada Ors, Isabel Sastre, José Fernández-Piqueras,  and María Villa-Morales
61485-61499
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The role of nerve microenvironment for neurofibroma development

The role of nerve microenvironment for neurofibroma development

https://doi.org/10.18632/oncotarget.11133

Chung-Ping Liao, Sanjay Pradhan, Zhiguo Chen, Amish J. Patel, Reid C. Booker,  and Lu Q. Le
61500-61508
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Salvianolic acid B, a novel autophagy inducer, exerts antitumor activity as a single agent in colorectal cancer cells

Salvianolic acid B, a novel autophagy inducer, exerts antitumor activity as a single agent in colorectal cancer cells

https://doi.org/10.18632/oncotarget.11385

Zhao Jing, Weiqiang Fei, Jichun Zhou, Lumin Zhang, Liuxi Chen, Xiaomin Zhang, Xiao Liang, Jiansheng Xie, Yong Fang, Xinbing Sui, Weidong Han,  and Hongming Pan
61509-61519
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YM155 sensitizes TRAIL-induced apoptosis through cathepsin S-dependent down-regulation of Mcl-1 and NF-κB-mediated down-regulation of c-FLIP expression in human renal carcinoma Caki cells

YM155 sensitizes TRAIL-induced apoptosis through cathepsin S-dependent down-regulation of Mcl-1 and NF-κB-mediated down-regulation of c-FLIP expression in human renal carcinoma Caki cells

https://doi.org/10.18632/oncotarget.11137

Seon Min Woo, Kyoung-jin Min, Bo Ram Seo,  and Taeg Kyu Kwon
61520-61532
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cumulative score based on preoperative plasma fibrinogen and serum C-reactive protein could predict long-term survival for esophageal squamous cell carcinoma

Cumulative score based on preoperative plasma fibrinogen and serum C-reactive protein could predict long-term survival for esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.11145

Rui Tian, Hong Yan, Fei Zhang, Peng Sun, Ai-Ran Wu, Min Zhang, Yu-Lu Jiang, Jing Wu, Yan-Hong Lu, Qiu-Yan Xu, Xiao-Hong Zhan, Rong-Xin Zhang, Li-Ting Qian,  and Jie He
61533-61543
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Therapeutic relevance of the protein phosphatase 2A in cancer

Therapeutic relevance of the protein phosphatase 2A in cancer

https://doi.org/10.18632/oncotarget.11399

Chelsea E. Cunningham, Shuangshuang Li, Frederick S. Vizeacoumar, Kalpana Kalyanasundaram Bhanumathy, Joo Sang Lee, Sreejit Parameswaran, Levi Furber, Omar Abuhussein, James M. Paul, Megan McDonald, Shaina D. Templeton, Hersh Shukla, Amr M. El Zawily, Frederick Boyd, Nezeka Alli, Darrell D. Mousseau, Ron Geyer, Keith Bonham, Deborah H. Anderson, Jiong Yan, Li-Yuan Yu-Lee, Beth A. Weaver, Maruti Uppalapati, Eytan Ruppin, Anna Sablina, Andrew Freywald,  and Franco J. Vizeacoumar
61544-61561
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pregnancy-specific glycoprotein 9 (PSG9), a driver for colorectal cancer, enhances angiogenesis via activation of SMAD4

Pregnancy-specific glycoprotein 9 (PSG9), a driver for colorectal cancer, enhances angiogenesis via activation of SMAD4

https://doi.org/10.18632/oncotarget.11146

Lei Yang, Shusheng Hu, Jinjing Tan, Xiaojing Zhang, Wen Yuan, Qian Wang, Lingling Xu, Jian Liu, Zheng Liu, Yanjun Jia,  and Xiaoxi Huang
61562-61574
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Targeted sequencing reveals TP53 as a potential diagnostic biomarker in the post-treatment surveillance of head and neck cancer

Targeted sequencing reveals TP53 as a potential diagnostic biomarker in the post-treatment surveillance of head and neck cancer

https://doi.org/10.18632/oncotarget.11196

Joost H. van Ginkel, Wendy W.J. de Leng, Remco de Bree, Robert J.J. van Es,  and Stefan M. Willems
61575-61586
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The requirement of SEPT2 and SEPT7 for migration and invasion in human breast cancer via MEK/ERK activation

The requirement of SEPT2 and SEPT7 for migration and invasion in human breast cancer via MEK/ERK activation

https://doi.org/10.18632/oncotarget.11402

Nianzhu Zhang, Lu Liu, Ning Fan, Qian Zhang, Weijie Wang, Mingnan Zheng, Lingfei Ma, Yan Li,  and Lei Shi
61587-61600
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Novel biomarkers of resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus

Novel biomarkers of resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus

https://doi.org/10.18632/oncotarget.11202

Eric Hastie, Marcela Cataldi, Megan J. Moerdyk-Schauwecker, Sébastien A. Felt, Nury Steuerwald,  and Valery Z. Grdzelishvili
61601-61618
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RhoGDIα suppresses self-renewal and tumorigenesis of glioma stem cells

RhoGDIα suppresses self-renewal and tumorigenesis of glioma stem cells

https://doi.org/10.18632/oncotarget.11423

Fan Wu, Peishan Hu, Dengke Li, Yan Hu, Yingjiao Qi, Bin Yin, Tao Jiang, Jiangang Yuan, Wei Han,  and Xiaozhong Peng
61619-61629
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Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells

Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells

https://doi.org/10.18632/oncotarget.11210

Daniel Menendez, Julie M. Lowe, Joyce Snipe,  and Michael A. Resnick
61630-61642
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Protective effects of Huangqin Decoction against ulcerative colitis and associated cancer in mice

Protective effects of Huangqin Decoction against ulcerative colitis and associated cancer in mice

https://doi.org/10.18632/oncotarget.11426

Gang Chen, Yang Yang, Chunping Hu, Xiaolan Cheng, Yuehua Xu, Xueting Cai, Min Wang, Chung S. Yang,  and Peng Cao
61643-61655
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Generation of TALEN-mediated FH knockout rat model

Generation of TALEN-mediated FH knockout rat model

https://doi.org/10.18632/oncotarget.11429

Dandan Yu, Yali Zhong, Xiaoran Li, Yaqing Li, Xiaoli Li, Jing Cao, Zhirui Fan, Huijie Fan, Long Yuan, Benling Xu, Yuan Yuan, Hongquan Zhang, Zhenyu Ji, Jian-Guo Wen, Mingzhi Zhang, Jahn M. Nesland,  and Zhenhe Suo
61656-61669
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KLRG1 restricts memory T cell antitumor immunity

KLRG1 restricts memory T cell antitumor immunity

https://doi.org/10.18632/oncotarget.11430

Lei Li, Shanshan Wan, Kaixiong Tao, Guobin Wang,  and Ende Zhao
61670-61678
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Patients with urothelial carcinoma have poor renal outcome regardless of whether they receive nephrouretectomy

Patients with urothelial carcinoma have poor renal outcome regardless of whether they receive nephrouretectomy

https://doi.org/10.18632/oncotarget.11223

Peir-Haur Hung, Hung-Bin Tsai, Kuan-Yu Hung, Chih-Hsin Muo, Mu-Chi Chung, Chao-Hsiang Chang,  and Chi-Jung Chung
61679-61689
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CD73 is associated with poor prognosis in HNSCC

CD73 is associated with poor prognosis in HNSCC

https://doi.org/10.18632/oncotarget.11435

Zhen-Hu Ren, Cheng-Zhong Lin, Wei Cao, Rong Yang, Wei Lu, Zhe-Qi Liu, Yi-Ming Chen, Xi Yang, Zhen Tian, Li-Zhen Wang, Jiang Li, Xu Wang, Wan-Tao Chen, Tong Ji,  and Chen-Ping Zhang
61690-61702
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Neferine inhibits proliferation and collagen synthesis induced by high glucose in cardiac fibroblasts and reduces cardiac fibrosis in diabetic mice

Neferine inhibits proliferation and collagen synthesis induced by high glucose in cardiac fibroblasts and reduces cardiac fibrosis in diabetic mice

https://doi.org/10.18632/oncotarget.11225

Xue Liu, Xiuhui Song, Jianjun Lu, Xueying Chen, Ershun Liang, Xiaoqiong Liu, Mingxiang Zhang, Yun Zhang, Zhanhui Du,  and Yuxia Zhao
61703-61715
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic variants of genes in the Notch signaling pathway predict overall survival of non-small cell lung cancer patients in the PLCO study

Genetic variants of genes in the Notch signaling pathway predict overall survival of non-small cell lung cancer patients in the PLCO study

https://doi.org/10.18632/oncotarget.11436

Yinghui Xu, Yanru Wang, Hongliang Liu, Xiaozheng Kang, Wei Li,  and Qingyi Wei
61716-61727
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Novel chemokine-like activities of histones in tumor metastasis

Novel chemokine-like activities of histones in tumor metastasis

https://doi.org/10.18632/oncotarget.11226

Ruochan Chen, Yangchun Xie, Xiao Zhong, Yongmin Fu, Yan Huang, Yixiang Zhen, Pinhua Pan, Haichao Wang, David L. Bartlett, Timothy R. Billiar, Michael T. Lotze, Herbert J. Zeh, III, Xue-Gong Fan, Daolin Tang,  and Rui Kang
61728-61740
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LncRNA ANRIL is up-regulated in nasopharyngeal carcinoma and promotes the cancer progression via increasing proliferation, reprograming cell glucose metabolism and inducing side-population stem-like cancer cells

LncRNA ANRIL is up-regulated in nasopharyngeal carcinoma and promotes the cancer progression via increasing proliferation, reprograming cell glucose metabolism and inducing side-population stem-like cancer cells

https://doi.org/10.18632/oncotarget.11437

Zhen Wei Zou, Charlie Ma, Lorraine Medoro, Lili Chen, Bin Wang, Roohi Gupta, Ting Liu, Xian Zi Yang, Tian Tian Chen, Ruo Zhen Wang, Wen Jie Zhang,  and Pin Dong Li
61741-61754
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mutational profiling of non-small-cell lung cancer patients resistant to first-generation EGFR tyrosine kinase inhibitors using next generation sequencing

Mutational profiling of non-small-cell lung cancer patients resistant to first-generation EGFR tyrosine kinase inhibitors using next generation sequencing

https://doi.org/10.18632/oncotarget.11237

Ying Jin, Yang Shao, Xun Shi, Guangyuan Lou, Yiping Zhang, Xue Wu, Xiaoling Tong,  and Xinmin Yu
61755-61763
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mesenchymal stem cells provide prophylaxis against acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation: A meta-analysis of animal models

Mesenchymal stem cells provide prophylaxis against acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation: A meta-analysis of animal models

https://doi.org/10.18632/oncotarget.11238

Li Wang, Haiyan Zhang, Lixun Guan, Shasha Zhao, Zhenyang Gu, Huaping Wei, Zhe Gao, Feiyan Wang, Nan Yang, Lan Luo, Yonghui Li, Lili Wang, Daihong Liu,  and Chunji Gao
61764-61774
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A bivalent promoter contributes to stress-induced plasticity of CXCR4 in Ewing sarcoma

A bivalent promoter contributes to stress-induced plasticity of CXCR4 in Ewing sarcoma

https://doi.org/10.18632/oncotarget.11240

Melanie A. Krook, Allegra G. Hawkins, Rajiv M. Patel, David R. Lucas, Raelene Van Noord, Rashmi Chugh,  and Elizabeth R. Lawlor
61775-61788
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors

CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors

https://doi.org/10.18632/oncotarget.11442

Khalil Ahmed, Betsy T. Kren, Md. Joynal Abedin, Rachel I. Vogel, Daniel P. Shaughnessy, Lucas Nacusi, Vicci L. Korman, Yingming Li, Scott M. Dehm, Cheryl L. Zimmerman, Gloria A. Niehans, Gretchen M. Unger,  and Janeen H. Trembley
61789-61805
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation

PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation

https://doi.org/10.18632/oncotarget.11241

Phaik Ju Teoh, Chonglei Bi, Chirackal Sintosebastian, Liang Seah Tay, Rafael Fonseca,  and Wee Joo Chng
61806-61819
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IL-8 promotes HNSCC progression on CXCR1/2-meidated NOD1/RIP2 signaling pathway

IL-8 promotes HNSCC progression on CXCR1/2-meidated NOD1/RIP2 signaling pathway

https://doi.org/10.18632/oncotarget.11445

Leong-Perng Chan, Ling-Feng Wang, Feng-Yu Chiang, Ka-Wo Lee, Po-Lin Kuo,  and Chia-Hua Liang
61820-61831
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Synergistic effect of reduced polypeptide micelle for co-delivery of doxorubicin and TRAIL against drug-resistance in breast cancer

Synergistic effect of reduced polypeptide micelle for co-delivery of doxorubicin and TRAIL against drug-resistance in breast cancer

https://doi.org/10.18632/oncotarget.11451

Chuling Hu, Fenfen Gu, Zongguang Tai, Chong Yao, Chunai Gong, Qingming Xia, Yuan Gao,  and Shen Gao
61832-61844
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Simultaneous detection of BRCA mutations and large genomic rearrangements in germline DNA and FFPE tumor samples

Simultaneous detection of BRCA mutations and large genomic rearrangements in germline DNA and FFPE tumor samples

https://doi.org/10.18632/oncotarget.11259

Márton Zsolt Enyedi, Gábor Jaksa, Lajos Pintér, Farkas Sükösd, Zoltán Gyuris, Adrienn Hajdu, Erika Határvölgyi, Katalin Priskin,  and Lajos Haracska
61845-61859
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in RELA-positive ependymoma

Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in RELA-positive ependymoma

https://doi.org/10.18632/oncotarget.11452

Theophilos Tzaridis, Till Milde, Kristian W. Pajtler, Sebastian Bender, David T. W. Jones, Simone Müller, Andrea Wittmann, Magdalena Schlotter, Andreas E. Kulozik, Peter Lichter, V. Peter Collins, Olaf Witt, Marcel Kool, Andrey Korshunov, Stefan M. Pfister,  and Hendrik Witt
61860-61873
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nucks1 synergizes with Trp53 to promote radiation lymphomagenesis in mice

Nucks1 synergizes with Trp53 to promote radiation lymphomagenesis in mice

https://doi.org/10.18632/oncotarget.11297

Yangbo Yue, Stanley G. Leung, Yueyong Liu, Yurong Huang, Kirsten Grundt, Anne-Carine Østvold, Kuang-Yu Jen, David Schild, Jian-Hua Mao,  and Claudia Wiese
61874-61889
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells

Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells

https://doi.org/10.18632/oncotarget.11301

Luigi Ippolito, Alberto Marini, Lorenzo Cavallini, Andrea Morandi, Laura Pietrovito, Gianfranco Pintus, Elisa Giannoni, Thomas Schrader, Martin Puhr, Paola Chiarugi,  and Maria Letizia Taddei
61890-61904
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Suppressive effects of sodium fluoride on cultured splenic lymphocyte proliferation in mice

Suppressive effects of sodium fluoride on cultured splenic lymphocyte proliferation in mice

https://doi.org/10.18632/oncotarget.11308

Ping Kuang, Huidan Deng, Hengmin Cui, Lian Chen, Hongrui Guo, Jing Fang, Zhicai Zuo, Junliang Deng, Xun Wang,  and Ling Zhao
61905-61915
Abstract  |  PDF  |  HTML  |  Order a Reprint

Validation of the high-performance of pyrosequencing for clinical MGMT testing on a cohort of glioblastoma patients from a prospective dedicated multicentric trial

Validation of the high-performance of pyrosequencing for clinical MGMT testing on a cohort of glioblastoma patients from a prospective dedicated multicentric trial

https://doi.org/10.18632/oncotarget.11322

Véronique Quillien, Audrey Lavenu, François Ducray, Marie-Odile Joly, Olivier Chinot, Frédéric Fina, Marc Sanson, Catherine Carpentier, Lucie Karayan-Tapon, Pierre Rivet, Natacha Entz-Werle, Michèle Legrain, Emmanuèle Lechapt Zalcman, Guenaelle Levallet, Fabienne Escande, Carole Ramirez, Dan Chiforeanu, Elodie Vauleon,  and Dominique Figarella-Branger
61916-61929
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The cytokine-cosmc signaling axis upregulates the tumor-associated carbohydrate antigen Tn

The cytokine-cosmc signaling axis upregulates the tumor-associated carbohydrate antigen Tn

https://doi.org/10.18632/oncotarget.11324

Chia-Wen Ho, Chi-Yu Lin, Yi-Wei Liaw, Hsiao-Ling Chiang, Yu-Tang Chin, Rui-Lan Huang, Hung-Cheng Lai, Yaw-Wen Hsu, Po-Jan Kuo, Chiao-En Chen, Hung-Yun Lin, Jacqueline Whang-Peng, Shin Nieh, Earl Fu, Leroy F. Liu,  and Jaulang Hwang
61930-61944
Abstract  |  PDF  |  HTML  |  Order a Reprint

Infarct volume after glioblastoma surgery as an independent prognostic factor

Infarct volume after glioblastoma surgery as an independent prognostic factor

https://doi.org/10.18632/oncotarget.11482

Stefanie Bette, Benedikt Wiestler, Johannes Kaesmacher, Thomas Huber, Julia Gerhardt, Melanie Barz, Claire Delbridge, Yu-Mi Ryang, Florian Ringel, Claus Zimmer, Bernhard Meyer, Tobias Boeckh-Behrens, Jan S. Kirschke,  and Jens Gempt
61945-61954
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activation of GRP/GRP-R signaling contributes to castration-resistant prostate cancer progression

Activation of GRP/GRP-R signaling contributes to castration-resistant prostate cancer progression

https://doi.org/10.18632/oncotarget.11326

Jingbo Qiao, Magdalena M. Grabowska, Ingrid S. Forestier-Roman, Janni Mirosevich, Thomas C. Case, Dai H. Chung, Justin M.M. Cates, Robert J. Matusik, Charles H. Manning,  and Renjie Jin
61955-61969
Abstract  |  PDF  |  HTML  |  Order a Reprint

Candidate germline polymorphisms of genes belonging to the pathways of four drugs used in osteosarcoma standard chemotherapy associated with risk, survival and toxicity in non-metastatic high-grade osteosarcoma

Candidate germline polymorphisms of genes belonging to the pathways of four drugs used in osteosarcoma standard chemotherapy associated with risk, survival and toxicity in non-metastatic high-grade osteosarcoma

https://doi.org/10.18632/oncotarget.11486

Claudia M. Hattinger, Paola Biason, Erika Iacoboni, Sara Gagno, Marilù Fanelli, Elisa Tavanti, Serena Vella, Stefano Ferrari, Andrea Roli, Rossana Roncato, Luciana Giodini, Katia Scotlandi, Piero Picci, Giuseppe Toffoli,  and Massimo Serra
61970-61987
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sorafenib inhibits cell growth but fails to enhance radio- and chemosensitivity of glioblastoma cell lines

Sorafenib inhibits cell growth but fails to enhance radio- and chemosensitivity of glioblastoma cell lines

https://doi.org/10.18632/oncotarget.11328

Matthias Riedel, Nina Struve, Justus Müller-Goebel, Sabrina Köcher, Cordula Petersen, Ekkehard Dikomey, Kai Rothkamm,  and Malte Kriegs
61988-61995
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association between whole grain intake and all-cause mortality: a meta-analysis of cohort studies

Association between whole grain intake and all-cause mortality: a meta-analysis of cohort studies

https://doi.org/10.18632/oncotarget.11491

Xiao Ma, Wei-Guo Tang, Yang Yang, Qing-Li Zhang, Jia-Li Zheng,  and Yong-Bing Xiang
61996-62005
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CXCL12-CXCR7 axis contributes to the invasive phenotype of pancreatic cancer

CXCL12-CXCR7 axis contributes to the invasive phenotype of pancreatic cancer

https://doi.org/10.18632/oncotarget.11330

Jun-Chao Guo, Jian Li, Li Zhou, Jian-Yu Yang, Zhi-Gang Zhang, Zhi-Yong Liang, Wei-Xun Zhou, Lei You, Tai-Ping Zhang,  and Yu-Pei Zhao
62006-62018
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ferritin heavy chain is a negative regulator of ovarian cancer stem cell expansion and epithelial to mesenchymal transition

Ferritin heavy chain is a negative regulator of ovarian cancer stem cell expansion and epithelial to mesenchymal transition

https://doi.org/10.18632/oncotarget.11495

Nadia Lobello, Flavia Biamonte, Maria Elena Pisanu, Maria Concetta Faniello, Žiga Jakopin, Emanuela Chiarella, Emilia Dora Giovannone, Rita Mancini, Gennaro Ciliberto, Giovanni Cuda,  and Francesco Costanzo
62019-62033
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Plasma microRNA profiles: identification of miR-23a as a novel biomarker for chemoresistance in esophageal squamous cell carcinoma

Plasma microRNA profiles: identification of miR-23a as a novel biomarker for chemoresistance in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.11500

Shuhei Komatsu, Daisuke Ichikawa, Tsutomu Kawaguchi, Hiroki Takeshita, Mahito Miyamae, Takuma Ohashi, Wataru Okajima, Taisuke Imamura, Jun Kiuchi, Tomohiro Arita, Hirotaka Konishi, Atsushi Shiozaki, Hitoshi Fujiwara, Kazuma Okamoto,  and Eigo Otsuji
62034-62048
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical significance of putative markers of cancer stem cells in gastric cancer: A retrospective cohort study

Clinical significance of putative markers of cancer stem cells in gastric cancer: A retrospective cohort study

https://doi.org/10.18632/oncotarget.11384

Xiao-Long Chen, Xin-Zu Chen, Yi-Gao Wang, Du He, Zheng-Hao Lu, Kai Liu, Wei-Han Zhang, Wei Wang, Chang-Chun Li, Lian Xue, Lin-Yong Zhao, Kun Yang, Jian-Ping Liu, Zong-Guang Zhou, Jian-Kun Hu,  and Xian-Ming Mo
62049-62069
Abstract  |  PDF  |  HTML  |  Order a Reprint

Ataxia-telangiectasia mutated activation mediates tumor necrosis factor-alpha induced MMP-13 up-regulation and metastasis in lung cancer cells

Ataxia-telangiectasia mutated activation mediates tumor necrosis factor-alpha induced MMP-13 up-regulation and metastasis in lung cancer cells

https://doi.org/10.18632/oncotarget.11386

Hong Qiong Yan, Di Zhang, Yuan Yuan Shi, Xiang You, Lei Shi, Qing Li,  and Feng Guang Gao
62070-62083
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A polymorphism rs4705341 in the flanking region of miR-143/145 predicts risk and prognosis of colorectal cancer

A polymorphism rs4705341 in the flanking region of miR-143/145 predicts risk and prognosis of colorectal cancer

https://doi.org/10.18632/oncotarget.11387

Ruifen Sun, Peng Chen, Lijuan Li, Hong Sun, Xinwen Nie, Yundan Liang, Fang Yuan, Yan Pu, Peng Bai, Lin Zhang,  and Linbo Gao
62084-62090
Abstract  |  PDF  |  HTML  |  Order a Reprint

Chk1 inhibition significantly potentiates activity of nucleoside analogs in TP53-mutated B-lymphoid cells

Chk1 inhibition significantly potentiates activity of nucleoside analogs in TP53-mutated B-lymphoid cells

https://doi.org/10.18632/oncotarget.11388

Jana Zemanova, Ondrej Hylse, Jana Collakova, Pavel Vesely, Alexandra Oltova, Marek Borsky, Kristina Zaprazna, Marie Kasparkova, Pavlina Janovska, Jan Verner, Jiri Kohoutek, Marta Dzimkova, Vitezslav Bryja, Zuzana Jaskova, Yvona Brychtova, Kamil Paruch,  and Martin Trbusek
62091-62106
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Diacetoxyscirpenol as a new anticancer agent to target hypoxia-inducible factor 1

Diacetoxyscirpenol as a new anticancer agent to target hypoxia-inducible factor 1

https://doi.org/10.18632/oncotarget.11529

Yong-Joon Choi, Hyun-Woo Shin, Yang-Sook Chun, Alain Simplice Leutou, Byeng Wha Son,  and Jong-Wan Park
62107-62122
Abstract  |  PDF  |  HTML  |  Order a Reprint

A novel inflammation-based prognostic score for patients with esophageal squamous cell carcinoma: the c-reactive protein/prognostic nutritional index ratio

A novel inflammation-based prognostic score for patients with esophageal squamous cell carcinoma: the c-reactive protein/prognostic nutritional index ratio

https://doi.org/10.18632/oncotarget.11389

Sheng Chen, Xun Yang,  and Ji-Feng Feng
62123-62132
Abstract  |  PDF  |  HTML  |  Order a Reprint

A polycomb-mediated epigenetic field defect precedes invasive cervical carcinoma

A polycomb-mediated epigenetic field defect precedes invasive cervical carcinoma

https://doi.org/10.18632/oncotarget.11390

Neil Ari Wijetunga, Miriam Ben-Dayan, Jessica Tozour, Robert D. Burk, Nicolas F. Schlecht, Mark H. Einstein,  and John M. Greally
62133-62143
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Lactoferrin selectively triggers apoptosis in highly metastatic breast cancer cells through inhibition of plasmalemmal V-H+-ATPase

Lactoferrin selectively triggers apoptosis in highly metastatic breast cancer cells through inhibition of plasmalemmal V-H+-ATPase

https://doi.org/10.18632/oncotarget.11394

Cátia S. Pereira, Joana P. Guedes, Marília Gonçalves, Luís Loureiro, Lisandra Castro, Hernâni Gerós, Lígia R. Rodrigues,  and Manuela Côrte-Real
62144-62158
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PADI4 has genetic susceptibility to gastric carcinoma and upregulates CXCR2, KRT14 and TNF-α expression levels

PADI4 has genetic susceptibility to gastric carcinoma and upregulates CXCR2, KRT14 and TNF-α expression levels

https://doi.org/10.18632/oncotarget.11398

Yabing Zheng, Gang Zhao, Bing Xu, Chunyan Liu, Chang Li, Xiaoqian Zhang,  and Xiaotian Chang
62159-62176
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gemcitabine enhances cell invasion via activating HAb18G/CD147-EGFR-pSTAT3 signaling

Gemcitabine enhances cell invasion via activating HAb18G/CD147-EGFR-pSTAT3 signaling

https://doi.org/10.18632/oncotarget.11405

Bao-Qing Xu, Zhi-Guang Fu, Yao Meng, Xiao-Qing Wu, Bo Wu, Liang Xu, Jian-Li Jiang, Ling Li,  and Zhi-Nan Chen
62177-62193
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression/activation of α5β1 integrin is linked to the β-catenin signaling pathway to drive migration in glioma cells

Expression/activation of α5β1 integrin is linked to the β-catenin signaling pathway to drive migration in glioma cells

https://doi.org/10.18632/oncotarget.11552

Guillaume Renner, Fanny Noulet, Marie-Cécile Mercier, Laurence Choulier, Nelly Etienne-Selloum, Jean-Pierre Gies, Maxime Lehmann, Isabelle Lelong-Rebel, Sophie Martin,  and Monique Dontenwill
62194-62207
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Knockdown of NEAT1 restrained the malignant progression of glioma stem cells by activating microRNA let-7e

Knockdown of NEAT1 restrained the malignant progression of glioma stem cells by activating microRNA let-7e

https://doi.org/10.18632/oncotarget.11403

Wei Gong, Jian Zheng, Xiaobai Liu, Jun Ma, Yunhui Liu,  and Yixue Xue
62208-62223
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TIPE2 suppresses angiogenesis and non-small cell lung cancer (NSCLC) invasiveness via inhibiting Rac1 activation and VEGF expression

TIPE2 suppresses angiogenesis and non-small cell lung cancer (NSCLC) invasiveness via inhibiting Rac1 activation and VEGF expression

https://doi.org/10.18632/oncotarget.11406

Zequn Li, Chun Guo, Xianglan Liu, Chengjun Zhou, Faliang Zhu, Xiaoyan Wang, Qun Wang, Yongyu Shi, Jianing Wang, Wei Zhao,  and Lining Zhang
62224-62239
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer

Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer

https://doi.org/10.18632/oncotarget.11404

Nooshin Mirkheshti, Sulgi Park, Shoulei Jiang, Jodie Cropper, Sherry L. Werner, Chung S. Song,  and Bandana Chatterjee
62240-62254
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Promising pharmacological profile of a Kunitz-type inhibitor in murine renal cell carcinoma model

Promising pharmacological profile of a Kunitz-type inhibitor in murine renal cell carcinoma model

https://doi.org/10.18632/oncotarget.11555

Jean Gabriel de Souza, Katia L.P. Morais, Eduardo Anglés-Cano, Pamela Boufleur, Evandro Sobroza de Mello, Durvanei Augusto Maria, Clarice Silvia Taemi Origassa, Hamilton de Campos Zampolli, Niels Olsen Saraiva Câmara, Carolina Maria Berra, Rosemary Viola Bosch,  and Ana Marisa Chudzinski-Tavassi
62255-62266
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Biological effect of an alternating electric field on cell proliferation and synergistic antimitotic effect in combination with ionizing radiation

Biological effect of an alternating electric field on cell proliferation and synergistic antimitotic effect in combination with ionizing radiation

https://doi.org/10.18632/oncotarget.11407

Eun Ho Kim, Ye Jin Kim, Hyo Sook Song, Youn Kyoung Jeong, Ji Young Lee, Jiwon Sung, Seung Hoon Yoo,  and Myonggeun Yoon
62267-62279
Abstract  |  PDF  |  HTML  |  Order a Reprint

Somatic mutations in plasma cell-free DNA are diagnostic markers for esophageal squamous cell carcinoma recurrence

Somatic mutations in plasma cell-free DNA are diagnostic markers for esophageal squamous cell carcinoma recurrence

https://doi.org/10.18632/oncotarget.11409

Masami Ueda, Tomohiro Iguchi, Takaaki Masuda, Yujiro Nakahara, Hidenari Hirata, Ryutaro Uchi, Atsushi Niida, Kota Momose, Shotaro Sakimura, Kenichi Chiba, Hidetoshi Eguchi, Shuhei Ito, Keishi Sugimachi, Makoto Yamasaki, Yutaka Suzuki, Satoru Miyano, Yuichiro Doki, Masaki Mori,  and Koshi Mimori
62280-62291
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Induction of exportin-5 expression during melanoma development supports the cellular behavior of human malignant melanoma cells

Induction of exportin-5 expression during melanoma development supports the cellular behavior of human malignant melanoma cells

https://doi.org/10.18632/oncotarget.11410

Corinna Anna Ott, Lisa Linck, Elisabeth Kremmer, Gunter Meister,  and Anja Katrin Bosserhoff
62292-62304
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A single nucleotide polymorphism in the 3’-UTR of STAT3 regulates its expression and reduces risk of pancreatic cancer in a Chinese population

A single nucleotide polymorphism in the 3’-UTR of STAT3 regulates its expression and reduces risk of pancreatic cancer in a Chinese population

https://doi.org/10.18632/oncotarget.11607

Beibei Zhu, Ying Zhu, Jiao Lou, Juntao Ke, Yi Zhang, Jiaoyuan Li, Yajie Gong, Yang Yang, Jianbo Tian, Xiating Peng, Danyi Zou, Rong Zhong, Jing Gong, Jiang Chang, Lu Li,  and Xiaoping Miao
62305-62311
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-34a regulates doxorubicin-induced cardiotoxicity in rat

MicroRNA-34a regulates doxorubicin-induced cardiotoxicity in rat

https://doi.org/10.18632/oncotarget.11468

Elena Piegari, Rosa Russo, Donato Cappetta, Grazia Esposito, Konrad Urbanek, Carmela Dell’Aversana, Lucia Altucci, Liberato Berrino, Francesco Rossi,  and Antonella De Angelis
62312-62326
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

eIF5B increases ASAP1 expression to promote HCC proliferation and invasion

eIF5B increases ASAP1 expression to promote HCC proliferation and invasion

https://doi.org/10.18632/oncotarget.11469

Zhen-guang Wang, Hao Zheng, Wei Gao, Jun Han, Jing-zhu Cao, Yuan Yang, Shuai Li, Rong Gao, Hui Liu, Ze-ya Pan, Si-yuan Fu, Fang-ming Gu, Hao Xing, Jun-sheng Ni, Hong-li Yan, Hao Ren,  and Wei-ping Zhou
62327-62339
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Suppression of PC-1/PrLZ sensitizes prostate cancer cells to ionizing radiation by attenuating DNA damage repair and inducing autophagic cell death

Suppression of PC-1/PrLZ sensitizes prostate cancer cells to ionizing radiation by attenuating DNA damage repair and inducing autophagic cell death

https://doi.org/10.18632/oncotarget.11470

Zeng-Fu Shang, Qiang Wei, Lan Yu, Fang Huang, Bei-Bei Xiao, Hongtao Wang, Man Song, Li Wang, Jianguang Zhou, Jian Wang,  and Shanhu Li
62340-62351
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Interleukin-6 expression contributes to lapatinib resistance through maintenance of stemness property in HER2-positive breast cancer cells

Interleukin-6 expression contributes to lapatinib resistance through maintenance of stemness property in HER2-positive breast cancer cells

https://doi.org/10.18632/oncotarget.11471

Wei-Chien Huang, Chao-Ming Hung, Ching-Ting Wei, Tsung-Ming Chen, Pei-Hsuan Chien, Hsiao-Lin Pan, Yueh-Ming Lin,  and Yun-Ju Chen
62352-62363
Abstract  |  PDF  |  HTML  |  Order a Reprint

miR-223 increases gallbladder cancer cell sensitivity to docetaxel by downregulating STMN1

miR-223 increases gallbladder cancer cell sensitivity to docetaxel by downregulating STMN1

https://doi.org/10.18632/oncotarget.11634

Wei Lu, Yunping Hu, Qiang Ma, Linzhu Zhou, Lin Jiang, Zhizhen Li, Shuai Zhao, Yuzhen Xu, Weibin Shi, Sheng Li,  and Yingbin Liu
62364-62376
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tetraspanin CD81 is an adverse prognostic marker in acute myeloid leukemia

Tetraspanin CD81 is an adverse prognostic marker in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.11481

Thomas Boyer, Soizic Guihard, Christophe Roumier, Pauline Peyrouze, Fanny Gonzales, Céline Berthon, Bruno Quesnel, Claude Preudhomme, Hélène Behal, Alain Duhamel, Catherine Roche-Lestienne,  and Meyling Cheok
62377-62385
Abstract  |  PDF  |  HTML  |  Order a Reprint

Inhibition of insulin-like growth factor II (IGF-II)-dependent cell growth by multidentate pentamannosyl 6-phosphate-based ligands targeting the mannose 6-phosphate/IGF-II receptor

Inhibition of insulin-like growth factor II (IGF-II)-dependent cell growth by multidentate pentamannosyl 6-phosphate-based ligands targeting the mannose 6-phosphate/IGF-II receptor

https://doi.org/10.18632/oncotarget.11493

Megan E. Zavorka, Christopher M. Connelly, Rosslyn Grosely,  and Richard G. MacDonald
62386-62410
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prevalence of human papillomavirus infection and genotyping for population-based cervical screening in developed regions in China

Prevalence of human papillomavirus infection and genotyping for population-based cervical screening in developed regions in China

https://doi.org/10.18632/oncotarget.11498

Yanru Zhang, Yueyun Wang, Li Liu, Chun Guo, Zhihua Liu,  and Shaofa Nie
62411-62424
Abstract  |  PDF  |  HTML  |  Order a Reprint

Human astrocytes secrete IL-6 to promote glioma migration and invasion through upregulation of cytomembrane MMP14

Human astrocytes secrete IL-6 to promote glioma migration and invasion through upregulation of cytomembrane MMP14

https://doi.org/10.18632/oncotarget.11515

Weiliang Chen, Tongliang Xia, Donghai Wang, Bin Huang, Peng Zhao, Jian Wang, Xun Qu,  and Xingang Li
62425-62438
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Natural nitration of CXCL12 reduces its signaling capacity and chemotactic activity in vitro and abrogates intra-articular lymphocyte recruitment in vivo

Natural nitration of CXCL12 reduces its signaling capacity and chemotactic activity in vitro and abrogates intra-articular lymphocyte recruitment in vivo

https://doi.org/10.18632/oncotarget.11516

Rik Janssens, Anneleen Mortier, Daiane Boff, Vincent Vanheule, Mieke Gouwy, Charlotte Franck, Olav Larsen, Mette M. Rosenkilde, Jo Van Damme, Flávio A. Amaral, Mauro M. Teixeira, Sofie Struyf,  and Paul Proost
62439-62459
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dihydroartemisinin suppresses pancreatic cancer cells via a microRNA-mRNA regulatory network

Dihydroartemisinin suppresses pancreatic cancer cells via a microRNA-mRNA regulatory network

https://doi.org/10.18632/oncotarget.11517

Yilong Li, Yongwei Wang, Rui Kong, Dongbo Xue, Shangha Pan, Hua Chen,  and Bei Sun
62460-62473
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long noncoding RNA CCAT1 acts as an oncogene and promotes chemoresistance in docetaxel-resistant lung adenocarcinoma cells

Long noncoding RNA CCAT1 acts as an oncogene and promotes chemoresistance in docetaxel-resistant lung adenocarcinoma cells

https://doi.org/10.18632/oncotarget.11518

Jing Chen, Kai Zhang, Haizhu Song, Rui Wang, Xiaoyuan Chu,  and Longbang Chen
62474-62489
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Soluble PD-L1: A biomarker to predict progression of autologous transplantation in patients with multiple myeloma

Soluble PD-L1: A biomarker to predict progression of autologous transplantation in patients with multiple myeloma

https://doi.org/10.18632/oncotarget.11519

Shang-Yi Huang, Hsiu-Hsia Lin, Chung-Wu Lin, Chi-Cheng Li, Ming Yao, Jih-Luh Tang, Hsin-An Hou, Woei Tsay, Sheng-Je Chou, Chieh-Lung Cheng,  and Hwei-Fang Tien
62490-62502
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

De-novo NAD+ synthesis regulates SIRT1-FOXO1 apoptotic pathway in response to NQO1 substrates in lung cancer cells

De-novo NAD+ synthesis regulates SIRT1-FOXO1 apoptotic pathway in response to NQO1 substrates in lung cancer cells

https://doi.org/10.18632/oncotarget.11526

Huiying Liu, Rong Xing, Xuefang Cheng, Qingran Li, Fang Liu, Hui Ye, Min Zhao, Hong Wang, Guangji Wang,  and Haiping Hao
62503-62519
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long non-coding RNA NKILA inhibits migration and invasion of tongue squamous cell carcinoma cells via suppressing epithelial-mesenchymal transition

Long non-coding RNA NKILA inhibits migration and invasion of tongue squamous cell carcinoma cells via suppressing epithelial-mesenchymal transition

https://doi.org/10.18632/oncotarget.11528

Wei Huang, Xiuying Cui, Jianing Chen, Yuhuan Feng, Erwei Song, Jinsong Li,  and Yujie Liu
62520-62532
Abstract  |  PDF  |  HTML  |  Order a Reprint

Generation and molecular characterization of pancreatic cancer patient-derived xenografts reveals their heterologous nature

Generation and molecular characterization of pancreatic cancer patient-derived xenografts reveals their heterologous nature

https://doi.org/10.18632/oncotarget.11530

Jaeyun Jung, Cue Hyunkyu Lee, Hyang Sook Seol, Yeon Sook Choi, Eunji Kim, Eun Ji Lee, Je-Keun Rhee, Shree Ram Singh, Eun Sung Jun, Buhm Han, Seung Mo Hong, Song Cheol Kim,  and Suhwan Chang
62533-62546
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Integrated analysis of genome-wide DNA methylation and gene expression profiles identifies potential novel biomarkers of rectal cancer

Integrated analysis of genome-wide DNA methylation and gene expression profiles identifies potential novel biomarkers of rectal cancer

https://doi.org/10.18632/oncotarget.11534

Jiufeng Wei, Guodong Li, Jinning Zhang, Yuhui Zhou, Shuwei Dang, Hongsheng Chen, Qiong Wu,  and Ming Liu
62547-62558
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mechanism of suppressors of cytokine signaling 1 inhibition of epithelial-mesenchymal transition signaling through ROS regulation in colon cancer cells: suppression of Src leading to thioredoxin up-regulation

Mechanism of suppressors of cytokine signaling 1 inhibition of epithelial-mesenchymal transition signaling through ROS regulation in colon cancer cells: suppression of Src leading to thioredoxin up-regulation

https://doi.org/10.18632/oncotarget.11537

Sung-Hoon Jung, Su-Min Kim,  and Choong-Eun Lee
62559-62571
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The novel compound STK405759 is a microtubule-targeting agent with potent and selective cytotoxicity against multiple myeloma in vitro and in vivo

The novel compound STK405759 is a microtubule-targeting agent with potent and selective cytotoxicity against multiple myeloma in vitro and in vivo

https://doi.org/10.18632/oncotarget.11539

Gabriela Rozic, Lena Paukov, Jana Jakubikova, Dikla Ben-Shushan, Adrian Duek, Adi Leiba, Abraham Avigdor, Arnon Nagler,  and Merav Leiba
62572-62584
Abstract  |  PDF  |  HTML  |  Order a Reprint

(-)-Guaiol regulates RAD51 stability via autophagy to induce cell apoptosis in non-small cell lung cancer

(-)-Guaiol regulates RAD51 stability via autophagy to induce cell apoptosis in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.11540

Qingyuan Yang, Jianchun Wu, Yingbin Luo, Nan Huang, Ni Zhen, Yun Zhou, Fenyong Sun, Zhi Li, Qiuhui Pan,  and Yan Li
62585-62597
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Evidence from a large-scale meta-analysis indicates eczema reduces the incidence of glioma

Evidence from a large-scale meta-analysis indicates eczema reduces the incidence of glioma

https://doi.org/10.18632/oncotarget.11545

Guannan Wang, Suling Xu, Chao Cao, Jing Dong, Yudong Chu, Guijuan He,  and Zhiwei Xu
62598-62606
Abstract  |  PDF  |  HTML  |  Order a Reprint

Optimization of the tumor microenvironment and nanomedicine properties simultaneously to improve tumor therapy

Optimization of the tumor microenvironment and nanomedicine properties simultaneously to improve tumor therapy

https://doi.org/10.18632/oncotarget.11546

Bo Zhang, Wei Shi, Ting Jiang, Lanting Wang, Heng Mei, Heng Lu, Yu Hu,  and Zhiqing Pang
62607-62618
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combining antiangiogenic therapy with neoadjuvant chemotherapy increases treatment efficacy in stage IIIA (N2) non-small cell lung cancer without increasing adverse effects

Combining antiangiogenic therapy with neoadjuvant chemotherapy increases treatment efficacy in stage IIIA (N2) non-small cell lung cancer without increasing adverse effects

https://doi.org/10.18632/oncotarget.11547

Xiaoliang Zhao, Yanjun Su, Jian You, Liqun Gong, Zhenfa Zhang, Meng Wang, Zhenqing Zhao, Zhen Zhang, Xiaolin Li,  and Changli Wang
62619-62626
Abstract  |  PDF  |  HTML  |  Order a Reprint

Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomas

Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomas

https://doi.org/10.18632/oncotarget.11548

Patricia Johansson, Ludger Klein-Hitpass, Florian Grabellus, Georg Arnold, Wolfram Klapper, Roman Pförtner, Ulrich Dührsen, Anja Eckstein, Jan Dürig,  and Ralf Küppers
62627-62639
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The independent association of mean platelet volume with overall survival in multiple myeloma

The independent association of mean platelet volume with overall survival in multiple myeloma

https://doi.org/10.18632/oncotarget.11551

Qiang Zhuang, Lina Xiang, Hanyan Xu, Fang Fang, Chongyun Xing, Bin Liang, Kang Yu,  and Jianhua Feng
62640-62646
Abstract  |  PDF  |  HTML  |  Order a Reprint

Sirolimus and metformin synergistically inhibit hepatocellular carcinoma cell proliferation and improve long-term survival in patients with HCC related to hepatitis B virus induced cirrhosis after liver transplantation

Sirolimus and metformin synergistically inhibit hepatocellular carcinoma cell proliferation and improve long-term survival in patients with HCC related to hepatitis B virus induced cirrhosis after liver transplantation

https://doi.org/10.18632/oncotarget.11591

Chuan Shen, Chenghong Peng, Baiyong Shen, Zhecheng Zhu, Ning Xu, Tao Li,  and Junjie Xie
62647-62656
Abstract  |  PDF  |  HTML  |  Order a Reprint

Initial intracranial pressure as a prognosticator in head-injured patients undergoing decompressive craniectomy

Initial intracranial pressure as a prognosticator in head-injured patients undergoing decompressive craniectomy

https://doi.org/10.18632/oncotarget.11632

Hua Liu, Rong Xu, Jian Yang, Guanghui Ren,  and Shengxue He
62657-62663
Abstract  |  PDF  |  HTML  |  Order a Reprint

Alterations of lymph nodes evaluation after colon cancer resection: patient and tumor heterogeneity should be taken into consideration

Alterations of lymph nodes evaluation after colon cancer resection: patient and tumor heterogeneity should be taken into consideration

https://doi.org/10.18632/oncotarget.11633

Xu Guan, Wei Chen, Shuai Li, Zheng Jiang, Zheng Liu, Zhixun Zhao, Song Wang, Ming Yang,  and Xishan Wang
62664-62675
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical Research Papers

Prognostic significance of survivin in rectal cancer patients treated with surgery and postoperative concurrent chemo-radiation therapy

Prognostic significance of survivin in rectal cancer patients treated with surgery and postoperative concurrent chemo-radiation therapy

https://doi.org/10.18632/oncotarget.10445

Jeong Il Yu, Hyebin Lee, Hee Chul Park, Doo Ho Choi, Yoon-La Choi, In-Gu Do, Hee Cheol Kim, Woo Yong Lee, Seong Hyeon Yun, Yong Beom Cho, Jung Wook Huh, Yoon Ah Park, Young Suk Park, Joon Oh Park, Seung Tae Kim,  and Won Park
62676-62686
Abstract  |  PDF  |  HTML  |  Order a Reprint

Sitagliptin and heart failure hospitalization in patients with type 2 diabetes

Sitagliptin and heart failure hospitalization in patients with type 2 diabetes

https://doi.org/10.18632/oncotarget.10507

Chin-Hsiao Tseng
62687-62696
Abstract  |  PDF  |  HTML  |  Order a Reprint

Predictive value of pedicle involvement with MRI in spine metastases

Predictive value of pedicle involvement with MRI in spine metastases

https://doi.org/10.18632/oncotarget.10884

Wang Mi Liu, Rong Xing, Chong Bian, Yun Liang, Libo Jiang, Chen Qian,  and Jian Dong
62697-62705
Abstract  |  PDF  |  HTML  |  Order a Reprint

Occult HBV infection in HCC and cirrhotic tissue of HBsAg-negative patients: a virological and clinical study

Occult HBV infection in HCC and cirrhotic tissue of HBsAg-negative patients: a virological and clinical study

https://doi.org/10.18632/oncotarget.10909

Nicola Coppola, Lorenzo Onorato, Valentina Iodice, Mario Starace, Carmine Minichini, Nunzia Farella, Giulia Liorre, Pietro Filippini, Evangelista Sagnelli,  and Giorgio de Stefano
62706-62714
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The effect of radiotherapy in liver-confined but non-resectable Barcelona Clinic Liver Cancer stage C large hepatocellular carcinoma

The effect of radiotherapy in liver-confined but non-resectable Barcelona Clinic Liver Cancer stage C large hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.10908

Hong In Yoon, Inkyung Jung, Kwang-Hyub Han,  and Jinsil Seong
62715-62725
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

Oncogenic regulation of tumor metabolic reprogramming

Oncogenic regulation of tumor metabolic reprogramming

https://doi.org/10.18632/oncotarget.10911

Míriam Tarrado-Castellarnau, Pedro de Atauri,  and Marta Cascante
62726-62753
Abstract  |  PDF  |  HTML  |  Order a Reprint

Technical challenges in the isolation and analysis of circulating tumor cells

Technical challenges in the isolation and analysis of circulating tumor cells

https://doi.org/10.18632/oncotarget.11191

Emma E. van der Toom, James E. Verdone, Michael A. Gorin,  and Kenneth J. Pienta
62754-62766
Abstract  |  PDF  |  HTML  |  Order a Reprint

AKT-ions with a TWIST between EMT and MET

AKT-ions with a TWIST between EMT and MET

https://doi.org/10.18632/oncotarget.11232

Huifang Tang, Daniela Massi, Brian A. Hemmings, Mario Mandalà, Zhengqiang Hu, Andreas Wicki,  and Gongda Xue
62767-62777
Abstract  |  PDF  |  HTML  |  Order a Reprint

The emerging role of miR-506 in cancer

The emerging role of miR-506 in cancer

https://doi.org/10.18632/oncotarget.11294

Jian Li, Jingfang Ju, Bing Ni,  and Huaizhi Wang
62778-62788
Abstract  |  PDF  |  HTML  |  Order a Reprint

HVPG signature: A prognostic and predictive tool in hepatocellular carcinoma

HVPG signature: A prognostic and predictive tool in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.11558

Xiaolong Qi, Xin Zhang, Zhijia Li, Jialiang Hui, Yi Xiang, Jinjun Chen, Jianbo Zhao, Jing Li, Fu-Zhen Qi,  and Yong Xu
62789-62796
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