Oncotarget

Vol 7, No 37

September 13, 2016

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About The Cover

The cover for issue 37 of Oncotarget features Figure 6B (Dermal fibroblasts with PDCD4 gene silencing promote formation of SCC with higher proliferative index and suppressed differentiation) from Jo, et al.

Table of Contents

Priority Research Papers

PDCD4 is a CSL associated protein with a transcription repressive function in cancer associated fibroblast activation

PDCD4 is a CSL associated protein with a transcription repressive function in cancer associated fibroblast activation

https://doi.org/10.18632/oncotarget.11227

Seung-Hee Jo, Dong Eun Kim, Andrea Clocchiatti,  and G. Paolo Dotto
58717-58727
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Heterogeneity in mechanisms of emergent resistance in pediatric T-cell acute lymphoblastic leukemia

Heterogeneity in mechanisms of emergent resistance in pediatric T-cell acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.11233

Babasaheb D. Yadav, Amy L. Samuels, Julia E. Wells, Rosemary Sutton, Nicola C. Venn, Katerina Bendak, Denise Anderson, Glenn M. Marshall, Catherine H. Cole, Alex H. Beesley, Ursula R. Kees,  and Richard B. Lock
58728-58742
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Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds

Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds

https://doi.org/10.18632/oncotarget.11318

Diego Carrella, Isabella Manni, Barbara Tumaini, Rosanna Dattilo, Federica Papaccio, Margherita Mutarelli, Francesco Sirci, Carla A. Amoreo, Marcella Mottolese, Manuela Iezzi, Laura Ciolli, Valentina Aria, Roberta Bosotti, Antonella Isacchi, Fabrizio Loreni, Alberto Bardelli, Vittorio E. Avvedimento, Diego di Bernardo,  and Luca Cardone
58743-58758
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Efficacy of ATR inhibitors as single agents in Ewing sarcoma

Efficacy of ATR inhibitors as single agents in Ewing sarcoma

https://doi.org/10.18632/oncotarget.11643

Maria Nieto-Soler, Isabel Morgado-Palacin, Vanesa Lafarga, Emilio Lecona, Matilde Murga, Elsa Callen, Daniel Azorin, Javier Alonso, Andres J. Lopez-Contreras, Andre Nussenzweig,  and Oscar Fernandez-Capetillo
58759-58767
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Priority Research Papers: Immunology

Zbtb1 prevents default myeloid differentiation of lymphoid-primed multipotent progenitors

Zbtb1 prevents default myeloid differentiation of lymphoid-primed multipotent progenitors

https://doi.org/10.18632/oncotarget.11356

Xianyu Zhang, Ying Lu, Xin Cao, Tao Zhen,  and Damian Kovalovsky
58768-58778
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Research Papers: Gerotarget (Focus on Aging)

MS4A6A genotypes are associated with the atrophy rates of Alzheimer’s disease related brain structures

MS4A6A genotypes are associated with the atrophy rates of Alzheimer’s disease related brain structures

https://doi.org/10.18632/oncotarget.9563

Jing Ma, Wei Zhang, Lin Tan, Hui-Fu Wang, Yu Wan, Fu-Rong Sun, Chen-Chen Tan, Jin-Tai Yu, Lan Tan,  and Alzheimer’s Disease Neuroimaging Initiative
58779-58788
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Protective effect of APOE epsilon 2 on intrinsic functional connectivity of the entorhinal cortex is associated with better episodic memory in elderly individuals with risk factors for Alzheimer’s disease

Protective effect of APOE epsilon 2 on intrinsic functional connectivity of the entorhinal cortex is associated with better episodic memory in elderly individuals with risk factors for Alzheimer’s disease

https://doi.org/10.18632/oncotarget.11289

Jiu Chen, Hao Shu, Zan Wang, Duan Liu, Yongmei Shi, Lin Xu,  and Zhijun Zhang
58789-58801
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Repetitive transcranial magnetic stimulation (rTMS) improves behavioral and biochemical deficits in levodopa-induced dyskinetic rats model

Repetitive transcranial magnetic stimulation (rTMS) improves behavioral and biochemical deficits in levodopa-induced dyskinetic rats model

https://doi.org/10.18632/oncotarget.11587

Maowen Ba, Min Kong, Lina Guan, Maoli Yi,  and Hongli Zhang
58802-58812
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Research Papers: Pathology

Loss of NEDD4 contributes to RTP801 elevation and neuron toxicity: implications for Parkinson’s disease

Loss of NEDD4 contributes to RTP801 elevation and neuron toxicity: implications for Parkinson’s disease

https://doi.org/10.18632/oncotarget.11020

Mercè Canal, Núria Martín-Flores, Leticia Pérez-Sisqués, Joan Romaní-Aumedes, Bekir Altas, Heng-Ye Man, Hiroshi Kawabe, Jordi Alberch,  and Cristina Malagelada
58813-58831
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Boar seminal plasma exosomes maintain sperm function by infiltrating into the sperm membrane

Boar seminal plasma exosomes maintain sperm function by infiltrating into the sperm membrane

https://doi.org/10.18632/oncotarget.11315

Jian Du, Jian Shen, Yuanxian Wang, Chuanying Pan, Weijun Pang, Hua Diao,  and Wuzi Dong
58832-58847
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Loss of prolyl hydroxylase domain protein 2 in vascular endothelium increases pericyte coverage and promotes pulmonary arterial remodeling

Loss of prolyl hydroxylase domain protein 2 in vascular endothelium increases pericyte coverage and promotes pulmonary arterial remodeling

https://doi.org/10.18632/oncotarget.11585

Shuo Wang, Heng Zeng, Xue-Jiao Xie, Yong-Kang Tao, Xiaochen He, Richard J. Roman, Judy L. Aschner,  and Jian-Xiong Chen
58848-58861
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Research Papers: Immunology

MYO9B gene polymorphisms are associated with the risk of inflammatory bowel diseases

MYO9B gene polymorphisms are associated with the risk of inflammatory bowel diseases

https://doi.org/10.18632/oncotarget.11186

Ming-Jie Wang, Xiao-Liang Xu, Guo-Liang Yao, Qiang Yu, Chun-Fu Zhu, Zhi-Jun Kong, Hui Zhao, Li-Ming Tang,  and Xi-Hu Qin
58862-58875
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Research Papers: Neuroscience

Glutamatergic stimulation induces GluN2B translation by the nitric oxide-Heme-Regulated eIF2α kinase in cortical neurons

Glutamatergic stimulation induces GluN2B translation by the nitric oxide-Heme-Regulated eIF2α kinase in cortical neurons

https://doi.org/10.18632/oncotarget.11417

Eva Ramos-Fernández, Marta Tajes, Gerard ILL-Raga, Lina Vargas, Arnau Busquets-García, Mònica Bosch-Morató, Biuse Guivernau, Victòria Valls-Comamala, Maria Gomis, Cristina Grau, César Fandos, Mark D. Rosen, Michael H. Rabinowitz, Nibaldo Inestrosa, Rafael Maldonado, Xavier Altafaj, Andrés Ozaita, Alejandra Alvarez, Rubén Vicente, Miguel A. Valverde,  and Francisco J. Muñoz
58876-58892
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Research Papers

hERG1/Kv11.1 activation stimulates transcription of p21waf/cip in breast cancer cells via a calcineurin-dependent mechanism

hERG1/Kv11.1 activation stimulates transcription of p21waf/cip in breast cancer cells via a calcineurin-dependent mechanism

https://doi.org/10.18632/oncotarget.3797

Mathew Perez-Neut, Vidhya R. Rao,  and Saverio Gentile
58893-58902
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Anaplastic lymphoma kinase aberrations correlate with metastatic features in pediatric rhabdomyosarcoma

Anaplastic lymphoma kinase aberrations correlate with metastatic features in pediatric rhabdomyosarcoma

https://doi.org/10.18632/oncotarget.10368

Patrizia Gasparini, Michela Casanova, Raffaella Villa, Paola Collini, Rita Alaggio, Angelica Zin, Paolo Bonvini, Cristina R Antonescu, Renata Boldrini, Roberto Caserini, Massimo Moro, Giovanni Centonze, Cristina Meazza, Maura Massimino, Luca Bergamaschi, Roberto Luksch, Stefano Chiaravalli, Gianni Bisogno, Nadia Zaffaroni, MariaGrazia Daidone, Gabriella Sozzi,  and Andrea Ferrari
58903-58914
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Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells

Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells

https://doi.org/10.18632/oncotarget.10410

Jui-Wen Ma, Chao-Ming Hung, Ying-Chao Lin, Chi-Tang Ho, Jung-Yie Kao,  and Tzong-Der Way
58915-58930
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Downregulated long non-coding RNA CLMAT3 promotes the proliferation of colorectal cancer cells by targeting regulators of the cell cycle pathway

Downregulated long non-coding RNA CLMAT3 promotes the proliferation of colorectal cancer cells by targeting regulators of the cell cycle pathway

https://doi.org/10.18632/oncotarget.10431

Le-chi Ye, Tao Chen, De-xiang Zhu, Shi-xu Lv, Jun-jun Qiu, Jianmin Xu, Feng-Lai Yuan,  and Ye Wei
58931-58938
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The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent

The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent

https://doi.org/10.18632/oncotarget.10624

Carmen Brenner, Judith Luciani, Martin Bizet, Matladi Ndlovu, Eleonore Josseaux, Sarah Dedeurwaerder, Emilie Calonne, Pascale Putmans, Pierre- Francois Cartron, Matthieu Defrance, François Fuks,  and Rachel Deplus
58939-58952
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Crosstalk between osteoprotegerin (OPG), fatty acid synthase (FASN) and, cycloxygenase-2 (COX-2) in breast cancer: implications in carcinogenesis

Crosstalk between osteoprotegerin (OPG), fatty acid synthase (FASN) and, cycloxygenase-2 (COX-2) in breast cancer: implications in carcinogenesis

https://doi.org/10.18632/oncotarget.9835

Sudeshna Goswami,  and Neelam Sharma-Walia
58953-58974
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PreImplantation factor (PIF) therapy provides comprehensive protection against radiation induced pathologies

PreImplantation factor (PIF) therapy provides comprehensive protection against radiation induced pathologies

https://doi.org/10.18632/oncotarget.10635

Reut Shainer, Osnat Almogi-Hazan, Arye Berger, Liad Hinden, Martin Mueller, Chaya Brodie, Cedric Simillion, Michael Paidas, Eytan R. Barnea,  and Reuven Or
58975-58994
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Momordin Ic, a new natural SENP1 inhibitor, inhibits prostate cancer cell proliferation

Momordin Ic, a new natural SENP1 inhibitor, inhibits prostate cancer cell proliferation

https://doi.org/10.18632/oncotarget.10636

Jingjing Wu, Hu Lei, Jinfu Zhang, Xiangyun Chen, Caixia Tang, Weiwei Wang, Hanzhang Xu, Weilie Xiao, Wenli Gu,  and Yingli Wu
58995-59005
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VAV1-Cre mediated hematopoietic deletion of CBL and CBL-B leads to JMML-like aggressive early-neonatal myeloproliferative disease

VAV1-Cre mediated hematopoietic deletion of CBL and CBL-B leads to JMML-like aggressive early-neonatal myeloproliferative disease

https://doi.org/10.18632/oncotarget.10638

Wei An, Bhopal C. Mohapatra, Neha Zutshi, Timothy A. Bielecki, Benjamin T. Goez, Haitao Luan, Fany Iseka, Insha Mushtaq, Matthew D. Storck, Vimla Band,  and Hamid Band
59006-59016
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Tobacco smoking and methylation of genes related to lung cancer development

Tobacco smoking and methylation of genes related to lung cancer development

https://doi.org/10.18632/oncotarget.10007

Xu Gao, Yan Zhang, Lutz Philipp Breitling,  and Hermann Brenner
59017-59028
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A common variant within the HNF1B gene is associated with overall survival of multiple myeloma patients: results from the IMMEnSE consortium and meta-analysis

A common variant within the HNF1B gene is associated with overall survival of multiple myeloma patients: results from the IMMEnSE consortium and meta-analysis

https://doi.org/10.18632/oncotarget.10665

Rafael Ríos-Tamayo, Carmen Belén Lupiañez, Daniele Campa, Thomas Hielscher, Niels Weinhold, Joaquin Martínez-López, Andrés Jerez, Stefano Landi, Krzysztof Jamroziak, Charles Dumontet, Marzena Wątek, Fabienne Lesueur, Rui Manuel Reis, Herlander Marques, Artur Jurczyszyn, Ulla Vogel, Gabriele Buda, Ramón García-Sanz, Enrico Orciuolo, Mario Petrini, Annette J. Vangsted, Federica Gemignani, Asta Försti, Hartmut Goldschmidt, Kari Hemminki, Federico Canzian, Manuel Jurado,  and Juan Sainz
59029-59048
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Comparison of small biopsy specimens and surgical specimens for the detection of EGFR mutations and EML4-ALK in non-small-cell lung cancer

Comparison of small biopsy specimens and surgical specimens for the detection of EGFR mutations and EML4-ALK in non-small-cell lung cancer

https://doi.org/10.18632/oncotarget.10011

DeSheng Xiao, Can Lu, Wei Zhu, QiuYan He, Yong Li, ChunYan Fu, JianHua Zhou, Shuang Liu,  and YongGuang Tao
59049-59057
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Molecular characteristics of circulating tumor cells resemble the liver metastasis more closely than the primary tumor in metastatic colorectal cancer

Molecular characteristics of circulating tumor cells resemble the liver metastasis more closely than the primary tumor in metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.10175

Wendy Onstenk, Anieta M. Sieuwerts, Bianca Mostert, Zarina Lalmahomed, Joan B. Bolt-de Vries, Anne van Galen, Marcel Smid, Jaco Kraan, Mai Van, Vanja de Weerd, Raquel Ramírez-Moreno, Katharina Biermann, Cornelis Verhoef, Dirk J. Grünhagen, Jan N.M. IJzermans, Jan W. Gratama, John W.M. Martens, John A. Foekens,  and Stefan Sleijfer
59058-59069
Abstract  |  PDF  |  HTML  |  Order a Reprint

The microRNA signature of patients with sunitinib failure: regulation of UHRF1 pathways by microRNA-101 in renal cell carcinoma

The microRNA signature of patients with sunitinib failure: regulation of UHRF1 pathways by microRNA-101 in renal cell carcinoma

https://doi.org/10.18632/oncotarget.10887

Yusuke Goto, Akira Kurozumi, Nijiro Nohata, Satoko Kojima, Ryosuke Matsushita, Hirofumi Yoshino, Kazuto Yamazaki, Yasuo Ishida, Tomohiko Ichikawa, Yukio Naya,  and Naohiko Seki
59070-59086
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Vorinostat and hydroxychloroquine improve immunity and inhibit autophagy in metastatic colorectal cancer

Vorinostat and hydroxychloroquine improve immunity and inhibit autophagy in metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.10824

Sukeshi Patel, Vincent Hurez, Steffan T. Nawrocki, Martin Goros, Joel Michalek, John Sarantopoulos, Tyler Curiel,  and Devalingam Mahalingam
59087-59097
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Co-expression modules of NF1, PTEN and sprouty enable distinction of adult diffuse gliomas according to pathway activities of receptor tyrosine kinases

Co-expression modules of NF1, PTEN and sprouty enable distinction of adult diffuse gliomas according to pathway activities of receptor tyrosine kinases

https://doi.org/10.18632/oncotarget.10359

Wanyu Zhang, Yuhong Lv, Yang Xue, Chenxing Wu, Kun Yao, Chuanbao Zhang, Qiang Jin, Rong Huang, Jiuyi Li, Yingyu Sun, Xiaodong Su, Tao Jiang,  and Xiaolong Fan
59098-59114
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Single-strand DNA library preparation improves sequencing of formalin-fixed and paraffin-embedded (FFPE) cancer DNA

Single-strand DNA library preparation improves sequencing of formalin-fixed and paraffin-embedded (FFPE) cancer DNA

https://doi.org/10.18632/oncotarget.10827

Mathias Stiller, Antje Sucker, Klaus Griewank, Daniela Aust, Gustavo Bruno Baretton, Dirk Schadendorf,  and Susanne Horn
59115-59128
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia

Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia

https://doi.org/10.18632/oncotarget.10991

Pasqualina Liana Scognamiglio, Concetta Di Natale, Marilisa Leone, Roberta Cascella, Cristina Cecchi, Lisa Lirussi, Giulia Antoniali, Domenico Riccardi, Giancarlo Morelli, Gianluca Tell, Fabrizio Chiti,  and Daniela Marasco
59129-59143
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Loss of ZFP36 expression in colorectal cancer correlates to wnt/ β-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of ZEB1, SOX9 and MACC1

Loss of ZFP36 expression in colorectal cancer correlates to wnt/ β-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of ZEB1, SOX9 and MACC1

https://doi.org/10.18632/oncotarget.10828

Lucia Montorsi, Filippo Guizzetti, Claudia Alecci, Andrea Caporali, Andrea Martello, Claudio Giacinto Atene, Sandra Parenti, Silvia Pizzini, Paola Zanovello, Stefania Bortoluzzi, Sergio Ferrari, Alexis Grande,  and Tommaso Zanocco-Marani
59144-59157
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PATZ1 expression correlates positively with BAX and negatively with BCL6 and survival in human diffuse large B cell lymphomas

PATZ1 expression correlates positively with BAX and negatively with BCL6 and survival in human diffuse large B cell lymphomas

https://doi.org/10.18632/oncotarget.10993

Renato Franco, Giosuè Scognamiglio, Elena Valentino, Michela Vitiello, Antonio Luciano, Giuseppe Palma, Claudio Arra, Elvira La Mantia, Luigi Panico, Valentina Tenneriello, Antonello Pinto, Ferdinando Frigeri, Gaetana Capobianco, Gerardo Botti, Laura Cerchia, Annarosaria De Chiara,  and Monica Fedele
59158-59172
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumor cells derived exosomes contain hTERT mRNA and transform nonmalignant fibroblasts into telomerase positive cells

Tumor cells derived exosomes contain hTERT mRNA and transform nonmalignant fibroblasts into telomerase positive cells

https://doi.org/10.18632/oncotarget.10384

Anna Gutkin, Orit Uziel, Einat Beery, Jardena Nordenberg, Maria Pinchasi, Hadar Goldvaser, Steven Henick, Michal Goldberg,  and Meir Lahav
59173-59188
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Prediction and diagnosis of renal cell carcinoma using nuclear magnetic resonance-based serum metabolomics and self-organizing maps

Prediction and diagnosis of renal cell carcinoma using nuclear magnetic resonance-based serum metabolomics and self-organizing maps

https://doi.org/10.18632/oncotarget.10830

Hong Zheng, Jiansong Ji, Liangcai Zhao, Minjiang Chen, An Shi, Linlin Pan, Yiran Huang, Huajie Zhang, Baijun Dong,  and Hongchang Gao
59189-59198
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Role of α7-nicotinic acetylcholine receptor in nicotine-induced invasion and epithelial-to-mesenchymal transition in human non-small cell lung cancer cells

Role of α7-nicotinic acetylcholine receptor in nicotine-induced invasion and epithelial-to-mesenchymal transition in human non-small cell lung cancer cells

https://doi.org/10.18632/oncotarget.10498

Chun Zhang, Xu-Ping Ding, Qing-Nan Zhao, Xin-Jie Yang, Shi-Min An, Hao Wang, Lu Xu, Liang Zhu,  and Hong-Zhuan Chen
59199-59208
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Epigenetic reprogramming and aberrant expression of PRAME are associated with increased metastatic risk in Class 1 and Class 2 uveal melanomas

Epigenetic reprogramming and aberrant expression of PRAME are associated with increased metastatic risk in Class 1 and Class 2 uveal melanomas

https://doi.org/10.18632/oncotarget.10962

Matthew G. Field, Michael A. Durante, Christina L. Decatur, Bercin Tarlan, Kristen M. Oelschlager, John F. Stone, Jeffim Kuznetsov, Anne M. Bowcock, Stefan Kurtenbach,  and J. William Harbour
59209-59219
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Xanthine oxidoreductase is required for genotoxic stress-induced NKG2D ligand expression and gemcitabine-mediated antitumor activity

Xanthine oxidoreductase is required for genotoxic stress-induced NKG2D ligand expression and gemcitabine-mediated antitumor activity

https://doi.org/10.18632/oncotarget.11042

Xiulong Xu, Geetha Rao,  and Yi Li
59220-59235
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Apatinib inhibits cellular invasion and migration by fusion kinase KIF5B-RET via suppressing RET/Src signaling pathway

Apatinib inhibits cellular invasion and migration by fusion kinase KIF5B-RET via suppressing RET/Src signaling pathway

https://doi.org/10.18632/oncotarget.10985

Chen Lin, Shanshan Wang, Weiwei Xie, Rongliang Zheng, Yu Gan,  and Jianhua Chang
59236-59244
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FOXM1 confers resistance to gefitinib in lung adenocarcinoma via a MET/AKT-dependent positive feedback loop

FOXM1 confers resistance to gefitinib in lung adenocarcinoma via a MET/AKT-dependent positive feedback loop

https://doi.org/10.18632/oncotarget.11043

Yu Wang, Weiwei Zhang, Li Wen, Huiling Yang, Mingling Wen, Yuyu Yun, Lisheng Zhao, Xiaofei Zhu, Li Tian, Erping Luo, Yu Li, Wenchao Liu,  and Ning Wen
59245-59259
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia

CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.10610

Chiara Palmi, Angela M. Savino, Daniela Silvestri, Ilaria Bronzini, Gunnar Cario, Maddalena Paganin, Barbara Buldini, Marta Galbiati, Martina U. Muckenthaler, Cristina Bugarin, Pamela Della Mina, Stefan Nagel, Elena Barisone, Fiorina Casale, Franco Locatelli, Luca Lo Nigro, Concetta Micalizzi, Rosanna Parasole, Andrea Pession, Maria C. Putti, Nicola Santoro, Anna M. Testi, Ottavio Ziino, Andreas E. Kulozik, Martin Zimmermann, Martin Schrappe, Antonello Villa, Giuseppe Gaipa, Giuseppe Basso, Andrea Biondi, Maria G. Valsecchi, Martin Stanulla, Valentino Conter, Geertruy te Kronnie,  and Giovanni Cazzaniga
59260-59272
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting the RAS/MAPK pathway with miR-181a in acute myeloid leukemia

Targeting the RAS/MAPK pathway with miR-181a in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.11150

Xiaomeng Huang, Sebastian Schwind, Ramasamy Santhanam, Ann-Kathrin Eisfeld, Chi-ling Chiang, Malori Lankenau, Bo Yu, Pia Hoellerbauer, Yan Jin, Somayeh S. Tarighat, Jihane Khalife, Alison Walker, Danilo Perrotti, Clara D. Bloomfield, Hongyan Wang, Robert J. Lee, Ly James Lee,  and Guido Marcucci
59273-59286
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-146a-5p inhibits cell proliferation and cell cycle progression in NSCLC cell lines by targeting CCND1 and CCND2

MiR-146a-5p inhibits cell proliferation and cell cycle progression in NSCLC cell lines by targeting CCND1 and CCND2

https://doi.org/10.18632/oncotarget.11040

Yan-Li Li, Ju Wang, Cai-Yan Zhang, Yu-Qing Shen, Hui-Min Wang, Lei Ding, Yu-Chen Gu, Jia-Tao Lou, Xin-Tai Zhao, Zhong-Liang Ma,  and You-Xin Jin
59287-59298
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of uracil DNA glycosylase sensitizes cancer cells to 5-fluorodeoxyuridine through replication fork collapse-induced DNA damage

Inhibition of uracil DNA glycosylase sensitizes cancer cells to 5-fluorodeoxyuridine through replication fork collapse-induced DNA damage

https://doi.org/10.18632/oncotarget.11151

Yan Yan, Xiangzi Han, Yulan Qing, Allison G. Condie, Shashank Gorityala, Shuming Yang, Yan Xu, Youwei Zhang,  and Stanton L. Gerson
59299-59313
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Positive nuclear BAP1 immunostaining helps differentiate non-small cell lung carcinomas from malignant mesothelioma

Positive nuclear BAP1 immunostaining helps differentiate non-small cell lung carcinomas from malignant mesothelioma

https://doi.org/10.18632/oncotarget.10653

Michele Carbone, David Shimizu, Andrea Napolitano, Mika Tanji, Harvey I. Pass, Haining Yang,  and Sandra Pastorino
59314-59321
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Preclinical activity of melflufen (J1) in ovarian cancer

Preclinical activity of melflufen (J1) in ovarian cancer

https://doi.org/10.18632/oncotarget.11163

Charlotte Carlier, Sara Strese, Kristina Viktorsson, Ebba Velander, Peter Nygren, Maria Uustalu, Therese Juntti, Rolf Lewensohn, Rolf Larsson, Jack Spira, Elly De Vlieghere, Wim P. Ceelen,  and Joachim Gullbo
59322-59335
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Establishment of a large panel of patient-derived preclinical models of human renal cell carcinoma

Establishment of a large panel of patient-derived preclinical models of human renal cell carcinoma

https://doi.org/10.18632/oncotarget.10659

Hervé Lang, Claire Béraud, Audrey Bethry, Sabrina Danilin, Véronique Lindner, Catherine Coquard, Sylvie Rothhut,  and Thierry Massfelder
59336-59359
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Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells

Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells

https://doi.org/10.18632/oncotarget.10661

Natalie Grinshtein, Constanza C. Rioseco, Richard Marcellus, David Uehling, Ahmed Aman, Xueqing Lun, Osamu Muto, Lauren Podmore, Jake Lever, Yaoqing Shen, Michael D. Blough, Greg J. Cairncross, Stephen M. Robbins, Steven J. Jones, Marco A. Marra, Rima Al-Awar, Donna L. Senger,  and David R. Kaplan
59360-59376
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XB130 is overexpressed in prostate cancer and involved in cell growth and invasion

XB130 is overexpressed in prostate cancer and involved in cell growth and invasion

https://doi.org/10.18632/oncotarget.11074

Bin Chen, Mengying Liao, Qiang Wei, Feiye Liu, Qinsong Zeng, Wei Wang, Jun Liu, Jianing Hou, Xinpei Yu,  and Jian Liu
59377-59387
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HDAC10 promotes lung cancer proliferation via AKT phosphorylation

HDAC10 promotes lung cancer proliferation via AKT phosphorylation

https://doi.org/10.18632/oncotarget.10673

Yiwei Yang, Yitong Huang, Zhantong Wang, Hsin-tzu Wang, Baoyu Duan, Dan Ye, Chenxin Wang, Ruiqi Jing, Ye Leng, Jiajie Xi, Wen Chen, Guiying Wang, Wenwen Jia, Songcheng Zhu,  and Jiuhong Kang
59388-59401
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Novel miR-122 delivery system based on MS2 virus like particle surface displaying cell-penetrating peptide TAT for hepatocellular carcinoma

Novel miR-122 delivery system based on MS2 virus like particle surface displaying cell-penetrating peptide TAT for hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.10681

Guojing Wang, Tingting Jia, Xixia Xu, Le Chang, Rui Zhang, Yu Fu, Yulong Li, Xin Yang, Kuo Zhang, Guigao Lin, Yanxi Han,  and Jinming Li
59402-59416
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A general strategy to optimize immunogenicity of HLA-B*0702 restricted cryptic peptides from tumor associated antigens: Design of universal neo-antigen like tumor vaccines for HLA-B*0702 positive patients

A general strategy to optimize immunogenicity of HLA-B*0702 restricted cryptic peptides from tumor associated antigens: Design of universal neo-antigen like tumor vaccines for HLA-B*0702 positive patients

https://doi.org/10.18632/oncotarget.11086

Catherine Gallou, Aude Rougeot, Stéphanie Graff-Dubois, Kostas Kosmatopoulos,  and Jeanne Menez-Jamet
59417-59428
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IL-1β-stimulated β-catenin up-regulation promotes angiogenesis in human lung-derived mesenchymal stromal cells through a NF-κB-dependent microRNA-433 induction

IL-1β-stimulated β-catenin up-regulation promotes angiogenesis in human lung-derived mesenchymal stromal cells through a NF-κB-dependent microRNA-433 induction

https://doi.org/10.18632/oncotarget.10683

Jia Sun, Jintao Chen, Juan Cao, Tianxiang Li, Shaoxia Zhuang,  and Xiufeng Jiang
59429-59440
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TIMP-1 is under regulation of the EGF signaling axis and promotes an aggressive phenotype in KRAS-mutated colorectal cancer cells: a potential novel approach to the treatment of metastatic colorectal cancer

TIMP-1 is under regulation of the EGF signaling axis and promotes an aggressive phenotype in KRAS-mutated colorectal cancer cells: a potential novel approach to the treatment of metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.11118

Line S. Tarpgaard, Maj Sofie Ørum-Madsen, Ib J. Christensen, Cathrine Nordgaard, Julie Noer, Tormod K. Guren, Bengt Glimelius, Halfdan Sorbye, Tone Ikdahl, Elin H. Kure, Kjell M. Tveit, Hans J. Nielsen, Per Pfeiffer, Nils Brünner,  and José M. A. Moreira
59441-59457
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dichloroacetate and metformin synergistically suppress the growth of ovarian cancer cells

Dichloroacetate and metformin synergistically suppress the growth of ovarian cancer cells

https://doi.org/10.18632/oncotarget.10694

Bo Li, Xinzhe Li, Zhenhong Ni, Yan Zhang, Yijun Zeng, Xiaohuan Yan, Yan Huang, Jintao He, Xilin Lyu, Yaran Wu, Yuting Wang, Yingru Zheng,  and Fengtian He
59458-59470
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel anti-PSMA human scFv has the potential to be used as a diagnostic tool in prostate cancer

A novel anti-PSMA human scFv has the potential to be used as a diagnostic tool in prostate cancer

https://doi.org/10.18632/oncotarget.10697

Donghui Han, Jieheng Wu, Yueheng Han, Ming Wei, Sen Han, Ruihe Lin, Ziyong Sun, Fa Yang, Dian Jiao, Pin Xie, Lingling Zhang, An-Gang Yang, Aizhi Zhao, Weihong Wen,  and Weijun Qin
59471-59481
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Short-term pyrrolidine dithiocarbamate administration attenuates cachexia-induced alterations to muscle and liver in ApcMin/+ mice

Short-term pyrrolidine dithiocarbamate administration attenuates cachexia-induced alterations to muscle and liver in ApcMin/+ mice

https://doi.org/10.18632/oncotarget.10699

Aditi A. Narsale, Melissa J. Puppa, Justin P. Hardee, Brandon N. VanderVeen, Reilly T. Enos, E. Angela Murphy,  and James A. Carson
59482-59502
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metformin enhances TRAIL-induced apoptosis by Mcl-1 degradation via Mule in colorectal cancer cells

Metformin enhances TRAIL-induced apoptosis by Mcl-1 degradation via Mule in colorectal cancer cells

https://doi.org/10.18632/oncotarget.11147

Seong Hye Park, Dae-Hee Lee, Jung Lim Kim, Bo Ram Kim, Yoo Jin Na, Min Jee Jo, Yoon A. Jeong, Suk-Young Lee, Sun Il Lee, Yong Yook Lee,  and Sang Cheul Oh
59503-59518
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The human box C/D snoRNAs U3 and U8 are required for pre-rRNA processing and tumorigenesis

The human box C/D snoRNAs U3 and U8 are required for pre-rRNA processing and tumorigenesis

https://doi.org/10.18632/oncotarget.11148

Jean-Louis Langhendries, Emilien Nicolas, Gilles Doumont, Serge Goldman,  and Denis L.J. Lafontaine
59519-59534
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

hERG1 behaves as biomarker of progression to adenocarcinoma in Barrett’s esophagus and can be exploited for a novel endoscopic surveillance

hERG1 behaves as biomarker of progression to adenocarcinoma in Barrett’s esophagus and can be exploited for a novel endoscopic surveillance

https://doi.org/10.18632/oncotarget.11149

Elena Lastraioli, Tiziano Lottini, Jessica Iorio, Giancarlo Freschi, Marilena Fazi, Claudia Duranti, Laura Carraresi, Luca Messerini, Antonio Taddei, Maria Novella Ringressi, Marianna Salemme, Vincenzo Villanacci, Carla Vindigni, Anna Tomezzoli, Roberta La Mendola, Maria Bencivenga, Bruno Compagnoni, Mariella Chiudinelli, Luca Saragoni, Ilaria Manzi, Giovanni De Manzoni, Paolo Bechi, Luca Boni,  and Annarosa Arcangeli
59535-59547
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Metformin use and cervical cancer risk in female patients with type 2 diabetes

Metformin use and cervical cancer risk in female patients with type 2 diabetes

https://doi.org/10.18632/oncotarget.10934

Chin-Hsiao Tseng
59548-59555
Abstract  |  PDF  |  HTML  |  Order a Reprint

Long non-coding RNA stabilizes the Y-box-binding protein 1 and regulates the epidermal growth factor receptor to promote lung carcinogenesis

Long non-coding RNA stabilizes the Y-box-binding protein 1 and regulates the epidermal growth factor receptor to promote lung carcinogenesis

https://doi.org/10.18632/oncotarget.10006

Ming-Ming Wei, Yong-Chun Zhou, Zhe-Sheng Wen, Bo Zhou, Yun-Chao Huang, Gui-Zhen Wang, Xin-Chun Zhao, Hong-Li Pan, Li-Wei Qu, Jian Zhang, Chen Zhang, Xin Cheng,  and Guang-Biao Zhou
59556-59571
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oleandrin induces DNA damage responses in cancer cells by suppressing the expression of Rad51

Oleandrin induces DNA damage responses in cancer cells by suppressing the expression of Rad51

https://doi.org/10.18632/oncotarget.10726

Zhengqiang Bao, Baoping Tian, Xiaohui Wang, Hanrong Feng, Ye Liang, Zhihua Chen, Wen Li, Huahao Shen,  and Songmin Ying
59572-59579
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Association of lncRNA H19 rs217727 polymorphism and cancer risk in the Chinese population: a meta-analysis

Association of lncRNA H19 rs217727 polymorphism and cancer risk in the Chinese population: a meta-analysis

https://doi.org/10.18632/oncotarget.10936

Yanjun Lu, Lu Tan, Na Shen, Jing Peng, Chunyu Wang, Yaowu Zhu,  and Xiong Wang
59580-59588
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ago-RIP-Seq identifies Polycomb repressive complex I member CBX7 as a major target of miR-375 in prostate cancer progression

Ago-RIP-Seq identifies Polycomb repressive complex I member CBX7 as a major target of miR-375 in prostate cancer progression

https://doi.org/10.18632/oncotarget.10729

Julia M.A. Pickl, Diana Tichy, Vladimir Y. Kuryshev, Yanis Tolstov, Michael Falkenstein, Julia Schüler, Daniel Reidenbach, Agnes Hotz-Wagenblatt, Glen Kristiansen, Wilfried Roth, Boris Hadaschik, Markus Hohenfellner, Stefan Duensing, Doreen Heckmann,  and Holger Sültmann
59589-59603
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Large intergenic non-coding RNA-ROR reverses gemcitabine-induced autophagy and apoptosis in breast cancer cells

Large intergenic non-coding RNA-ROR reverses gemcitabine-induced autophagy and apoptosis in breast cancer cells

https://doi.org/10.18632/oncotarget.10730

Yao-Min Chen, Yu Liu, Hai-Yan Wei, Ke-Zhen Lv,  and Pei-Fen Fu
59604-59617
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Statins dose-dependently exert a chemopreventive effect against lung cancer in COPD patients: a population-based cohort study

Statins dose-dependently exert a chemopreventive effect against lung cancer in COPD patients: a population-based cohort study

https://doi.org/10.18632/oncotarget.11162

Ju-Chi Liu, Tsung-Yeh Yang, Yi-Ping Hsu, Wen-Rui Hao, Pai-Feng Kao, Li-Chin Sung, Chun-Chao Chen,  and Szu-Yuan Wu
59618-59629
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A nomogram composed of clinicopathologic features and preoperative serum tumor markers to predict lymph node metastasis in early gastric cancer patients

A nomogram composed of clinicopathologic features and preoperative serum tumor markers to predict lymph node metastasis in early gastric cancer patients

https://doi.org/10.18632/oncotarget.10732

Lin-Yong Zhao, Yuan Yin, Xue Li, Chen-Jing Zhu, Yi-Gao Wang, Xiao-Long Chen, Wei-Han Zhang, Xin-Zu Chen, Kun Yang, Kai Liu, Bo Zhang, Zhi-Xin Chen, Jia-Ping Chen, Zong-Guang Zhou,  and Jian-Kun Hu
59630-59639
Abstract  |  PDF  |  HTML  |  Order a Reprint

High expression of cholesterol biosynthesis genes is associated with resistance to statin treatment and inferior survival in breast cancer

High expression of cholesterol biosynthesis genes is associated with resistance to statin treatment and inferior survival in breast cancer

https://doi.org/10.18632/oncotarget.10746

Siker Kimbung, Barbara Lettiero, Maria Feldt, Ana Bosch,  and Signe Borgquist
59640-59651
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Interleukin-11 promotes epithelial-mesenchymal transition in anaplastic thyroid carcinoma cells through PI3K/Akt/GSK3β signaling pathway activation

Interleukin-11 promotes epithelial-mesenchymal transition in anaplastic thyroid carcinoma cells through PI3K/Akt/GSK3β signaling pathway activation

https://doi.org/10.18632/oncotarget.10831

Zhaoming Zhong, Zedong Hu, Yue Jiang, Ruimei Sun, Xue Chen, Hongying Chu, Musheng Zeng,  and Chuanzheng Sun
59652-59663
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Plasma miR-324-3p and miR-1285 as diagnostic and prognostic biomarkers for early stage lung squamous cell carcinoma

Plasma miR-324-3p and miR-1285 as diagnostic and prognostic biomarkers for early stage lung squamous cell carcinoma

https://doi.org/10.18632/oncotarget.11198

Xujie Gao, Yang Wang, Hua Zhao, Feng Wei, Xinwei Zhang, Yanjun Su, Changli Wang, Hui Li,  and Xiubao Ren
59664-59675
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dysregulated long intergenic non-coding RNA modules contribute to heart failure

Dysregulated long intergenic non-coding RNA modules contribute to heart failure

https://doi.org/10.18632/oncotarget.10834

Lin Pang, Jing Hu, Guanxiong Zhang, Xiang Li, Xinxin Zhang, Fulong Yu, Yujia Lan, Jinyuan Xu, Bo Pang, Dong Han, Yun Xiao,  and Xia Li
59676-59690
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dihydromyricetin promotes autophagy and apoptosis through ROS-STAT3 signaling in head and neck squamous cell carcinoma

Dihydromyricetin promotes autophagy and apoptosis through ROS-STAT3 signaling in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.10836

Teng-Fei Fan, Tian-Fu Wu, Lin-Lin Bu, Si-Rui Ma, Yi-Cun Li, Liang Mao, Zhi-Jun Sun,  and Wen-Feng Zhang
59691-59703
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IRES-dependent translation of the long non coding RNA meloe in melanoma cells produces the most immunogenic MELOE antigens

IRES-dependent translation of the long non coding RNA meloe in melanoma cells produces the most immunogenic MELOE antigens

https://doi.org/10.18632/oncotarget.10923

Maud Charpentier, Mikael Croyal, Delphine Carbonnelle, Agnès Fortun, Laetitia Florenceau, Catherine Rabu, Michel Krempf, Nathalie Labarrière,  and François Lang
59704-59713
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-145 sensitizes breast cancer to doxorubicin by targeting multidrug resistance-associated protein-1

miR-145 sensitizes breast cancer to doxorubicin by targeting multidrug resistance-associated protein-1

https://doi.org/10.18632/oncotarget.10845

Man Gao, Lingling Miao, Mingxia Liu, Chenggang Li, Cunzhi Yu, Hong Yan, Yongxiang Yin, Yizheng Wang, Xinming Qi,  and Jin Ren
59714-59726
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Bortezomib-induced heat shock response protects multiple myeloma cells and is activated by heat shock factor 1 serine 326 phosphorylation

Bortezomib-induced heat shock response protects multiple myeloma cells and is activated by heat shock factor 1 serine 326 phosphorylation

https://doi.org/10.18632/oncotarget.10847

Shardule P. Shah, Ajay K. Nooka, David L. Jaye, Nizar J. Bahlis, Sagar Lonial,  and Lawrence H. Boise
59727-59741
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The breast cancer susceptibility-related polymorphisms at the TOX3/LOC643714 locus associated with lung cancer risk in a Han Chinese population

The breast cancer susceptibility-related polymorphisms at the TOX3/LOC643714 locus associated with lung cancer risk in a Han Chinese population

https://doi.org/10.18632/oncotarget.10874

Chaowen Jiang, Shilong Yu, Pin Qian, Ruiling Guo, Ruijie Zhang, Zhi Ao, Qi Li, Guoming Wu, Yan Chen, Jin Li, Changzheng Wang, Wei Yao, Jiancheng Xu, Guisheng Qian,  and Fuyun Ji
59742-59753
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Chemo-immunotherapy induces tumor regression in a mouse model of spontaneous mammary carcinogenesis

Chemo-immunotherapy induces tumor regression in a mouse model of spontaneous mammary carcinogenesis

https://doi.org/10.18632/oncotarget.10880

Eleonora Aricò, Paola Sestili, Giulia Carpinelli, Rossella Canese, Serena Cecchetti, Giovanna Schiavoni, Maria Teresa D’Urso, Filippo Belardelli,  and Enrico Proietti
59754-59765
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Carcinoma-associated fibroblasts affect sensitivity to oxaliplatin and 5FU in colorectal cancer cells

Carcinoma-associated fibroblasts affect sensitivity to oxaliplatin and 5FU in colorectal cancer cells

https://doi.org/10.18632/oncotarget.11121

Samuel Gonçalves-Ribeiro, Natalia Guillen Díaz-Maroto, Mireia Berdiel-Acer, Antonio Soriano, Jordi Guardiola, Mercedes Martínez-Villacampa, Ramon Salazar, Gabriel Capellà, Alberto Villanueva, Eva Martínez-Balibrea,  and David G. Molleví
59766-59780
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Critical role of androgen receptor level in prostate cancer cell resistance to new generation antiandrogen enzalutamide

Critical role of androgen receptor level in prostate cancer cell resistance to new generation antiandrogen enzalutamide

https://doi.org/10.18632/oncotarget.10926

Julia Hoefer, Mohammady Akbor, Florian Handle, Philipp Ofer, Martin Puhr, Walther Parson, Zoran Culig, Helmut Klocker,  and Isabel Heidegger
59781-59794
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells

Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells

https://doi.org/10.18632/oncotarget.10928

Kiyohiro Hashimoto, Vyom Sharma, Hiroyuki Sasanuma, Xu Tian, Minoru Takata, Shunichi Takeda, James A. Swenberg,  and Jun Nakamura
59795-59808
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dichloroacetate potentiates tamoxifen-induced cell death in breast cancer cells via downregulation of the epidermal growth factor receptor

Dichloroacetate potentiates tamoxifen-induced cell death in breast cancer cells via downregulation of the epidermal growth factor receptor

https://doi.org/10.18632/oncotarget.10999

Sang Hyeok Woo, Sung-Keum Seo, Yoonhwa Park, Eun-Kyu Kim, Min-Ki Seong, Hyun-Ah Kim, Jie-Young Song, Sang-Gu Hwang, Jin Kyung Lee, Woo Chul Noh,  and In-Chul Park
59809-59819
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Improved survival of patients with hepatocellular carcinoma and disparities by age, race, and socioeconomic status by decade, 1983–2012

Improved survival of patients with hepatocellular carcinoma and disparities by age, race, and socioeconomic status by decade, 1983–2012

https://doi.org/10.18632/oncotarget.10930

Shuncong Wang, Huanhuan Sun, Zhinan Xie, Jie Li, Guobin Hong, Dan Li, Saradhi Mallampati, Xiuling Zhou, Cuiling Zhou, Hongyu Zhang, Zhibin Cheng, Hong Shan,  and Haiqing Ma
59820-59833
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The 3′UTR signature defines a highly metastatic subgroup of triple-negative breast cancer

The 3′UTR signature defines a highly metastatic subgroup of triple-negative breast cancer

https://doi.org/10.18632/oncotarget.10975

Lei Wang, Xin Hu, Peng Wang,  and Zhi-Ming Shao
59834-59844
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MZF-1/Elk-1 interaction domain as therapeutic target for protein kinase Cα-based triple-negative breast cancer cells

MZF-1/Elk-1 interaction domain as therapeutic target for protein kinase Cα-based triple-negative breast cancer cells

https://doi.org/10.18632/oncotarget.11337

Chia-Jen Lee, Li-Sung Hsu, Chia-Herng Yue, Ho Lin, Yung-Wei Chiu, Yu-Yu Lin, Chih-Yang Huang, Mien-Chie Hung,  and Jer-Yuh Liu
59845-59859
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Simultaneous targeting of Eph receptors in glioblastoma

Simultaneous targeting of Eph receptors in glioblastoma

https://doi.org/10.18632/oncotarget.10978

Sara Ferluga, Carla Maria Lema Tomé, Denise Mazess Herpai, Ralph D’Agostino,  and Waldemar Debinski
59860-59876
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combined cell surface carbonic anhydrase 9 and CD147 antigens enable high-efficiency capture of circulating tumor cells in clear cell renal cell carcinoma patients

Combined cell surface carbonic anhydrase 9 and CD147 antigens enable high-efficiency capture of circulating tumor cells in clear cell renal cell carcinoma patients

https://doi.org/10.18632/oncotarget.10979

Shijie Liu, Zuhong Tian, Lei Zhang, Shuang Hou, Sijun Hu, Junshen Wu, Yuming Jing, Huimin Sun, Fei Yu, Libo Zhao, Ruoxiang Wang, Hsian-Rong Tseng, Haiyen E. Zhau, Leland W.K. Chung, Kaichun Wu, Hao Wang, Jason Boyang Wu, Yongzhan Nie,  and Chen Shao
59877-59891
Abstract  |  PDF  |  HTML  |  Order a Reprint

Blood concentration of cyclosporine during early post-transplant period may have influence on the occurrence of chronic graft versus host disease in patients who received allogeneic hematopoietic stem cell transplantation

Blood concentration of cyclosporine during early post-transplant period may have influence on the occurrence of chronic graft versus host disease in patients who received allogeneic hematopoietic stem cell transplantation

https://doi.org/10.18632/oncotarget.10988

Silvia Park, Kihyun Kim, Jun Ho Jang, Seok Jin Kim, Won Seog Kim,  and Chul Won Jung
59892-59901
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Advanced interstitial chemotherapy combined with targeted treatment of malignant glioma in rats by using drug-loaded nanofibrous membranes

Advanced interstitial chemotherapy combined with targeted treatment of malignant glioma in rats by using drug-loaded nanofibrous membranes

https://doi.org/10.18632/oncotarget.10989

Yuan-Yun Tseng, Chen-Hsing Su, Shun-Tai Yang, Yin-Chen Huang, Wei-Hwa Lee, Yi-Chuan Wang, Shou-Cheng Liu,  and Shih-Jung Liu
59902-59916
Abstract  |  PDF  |  HTML  |  Order a Reprint

Hop derived flavonoid xanthohumol inhibits endothelial cell functions via AMPK activation

Hop derived flavonoid xanthohumol inhibits endothelial cell functions via AMPK activation

https://doi.org/10.18632/oncotarget.10990

Cristina Gallo, Katiuscia Dallaglio, Barbara Bassani, Teresa Rossi, Armando Rossello, Douglas M. Noonan, Gabriele D’Uva, Antonino Bruno,  and Adriana Albini
59917-59931
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA 10b promotes abnormal expression of the proto-oncogene c-Jun in metastatic breast cancer cells

MicroRNA 10b promotes abnormal expression of the proto-oncogene c-Jun in metastatic breast cancer cells

https://doi.org/10.18632/oncotarget.11000

Revital Knirsh, Iris Ben-Dror, Shira Modai, Noam Shomron,  and Lily Vardimon
59932-59944
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Whether regional lymph nodes evaluation should be equally required for both right and left colon cancer

Whether regional lymph nodes evaluation should be equally required for both right and left colon cancer

https://doi.org/10.18632/oncotarget.11007

Xu Guan, Wei Chen, Zheng Liu, Zheng Jiang, Hanqing Hu, Zhixun Zhao, Song Wang, Yinggang Chen, Guiyu Wang,  and Xishan Wang
59945-59956
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Endoplasmic reticulum stress induces secretion of high-mobility group proteins and is associated with tumor-infiltrating lymphocytes in triple-negative breast cancer

Endoplasmic reticulum stress induces secretion of high-mobility group proteins and is associated with tumor-infiltrating lymphocytes in triple-negative breast cancer

https://doi.org/10.18632/oncotarget.11010

In Ah Park, Sun-Hee Heo, In Hye Song, Young-Ae Kim, Hye Seon Park, Won Seon Bang, Suk Young Park, Jeong-Hyon Jo, Hee Jin Lee,  and Gyungyub Gong
59957-59964
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A lupus anti-DNA autoantibody mediates autocatalytic, targeted delivery of nanoparticles to tumors

A lupus anti-DNA autoantibody mediates autocatalytic, targeted delivery of nanoparticles to tumors

https://doi.org/10.18632/oncotarget.11015

Zeming Chen, Jaymin M. Patel, Philip W. Noble, Cesar Garcia, Zhangyong Hong, James E. Hansen,  and Jiangbing Zhou
59965-59975
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PD-L1 expression in EBV-negative diffuse large B-cell lymphoma: clinicopathologic features and prognostic implications

PD-L1 expression in EBV-negative diffuse large B-cell lymphoma: clinicopathologic features and prognostic implications

https://doi.org/10.18632/oncotarget.11045

Wei Xing, Karen Dresser, Rui Zhang, Andrew M. Evens, Hongbo Yu, Bruce A. Woda,  and Benjamin J. Chen
59976-59986
Abstract  |  PDF  |  HTML  |  Order a Reprint

MALDI imaging reveals NCOA7 as a potential biomarker in oral squamous cell carcinoma arising from oral submucous fibrosis

MALDI imaging reveals NCOA7 as a potential biomarker in oral squamous cell carcinoma arising from oral submucous fibrosis

https://doi.org/10.18632/oncotarget.11046

Xiaoyan Xie, Yuchen Jiang, Yao Yuan, Peiqi Wang, Xinyi Li, Fangman Chen, Chongkui Sun, Hang Zhao, Xin Zeng, Lu Jiang, Yu Zhou, Hongxia Dan, Mingye Feng, Rui Liu,  and Qianming Chen
59987-60004
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The Fanconi anemia pathway controls oncogenic response in hematopoietic stem and progenitor cells by regulating PRMT5-mediated p53 arginine methylation

The Fanconi anemia pathway controls oncogenic response in hematopoietic stem and progenitor cells by regulating PRMT5-mediated p53 arginine methylation

https://doi.org/10.18632/oncotarget.11088

Wei Du, Surya Amarachintha, Ozlem Erden, Andrew Wilson,  and Qishen Pang
60005-60020
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Crosstalk between the mitochondrial fission protein, Drp1, and the cell cycle is identified across various cancer types and can impact survival of epithelial ovarian cancer patients

Crosstalk between the mitochondrial fission protein, Drp1, and the cell cycle is identified across various cancer types and can impact survival of epithelial ovarian cancer patients

https://doi.org/10.18632/oncotarget.11047

Deepak Kumar Tanwar, Danitra J. Parker, Priyanka Gupta, Brian Spurlock, Ronald D. Alvarez, Malay Kumar Basu,  and Kasturi Mitra
60021-60037
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nucleophosmin/B23 is a negative regulator of estrogen receptor α expression via AP2γ in endometrial cancer cells

Nucleophosmin/B23 is a negative regulator of estrogen receptor α expression via AP2γ in endometrial cancer cells

https://doi.org/10.18632/oncotarget.11048

Chiao-Yun Lin, Angel Chao, Tzu-Hao Wang, Li-Yu Lee, Lan-Yan Yang, Chia-Lung Tsai, Hsin-Shih Wang,  and Chyong-Huey Lai
60038-60052
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metabolomic analysis reveals altered metabolic pathways in a rat model of gastric carcinogenesis

Metabolomic analysis reveals altered metabolic pathways in a rat model of gastric carcinogenesis

https://doi.org/10.18632/oncotarget.11049

Jinping Gu, Xiaomin Hu, Wei Shao, Tianhai Ji, Wensheng Yang, Huiqin Zhuo, Zeyu Jin, Huiying Huang, Jiacheng Chen, Caihua Huang,  and Donghai Lin
60053-60073
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Upregulation of miR-181c inhibits chemoresistance by targeting ST8SIA4 in chronic myelocytic leukemia

Upregulation of miR-181c inhibits chemoresistance by targeting ST8SIA4 in chronic myelocytic leukemia

https://doi.org/10.18632/oncotarget.11054

Lifen Zhao, Yan Li, Xiaobo Song, Huimin Zhou, Nana Li, Yuan Miao,  and Li Jia
60074-60086
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RAD51 inhibition in triple negative breast cancer cells is challenged by compensatory survival signaling and requires rational combination therapy

RAD51 inhibition in triple negative breast cancer cells is challenged by compensatory survival signaling and requires rational combination therapy

https://doi.org/10.18632/oncotarget.11065

Adrian P. Wiegmans, Mariska Miranda, Shu Wen Wen, Fares Al-Ejeh,  and Andreas Möller
60087-60100
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Short term ex-vivo expansion of circulating head and neck tumour cells

Short term ex-vivo expansion of circulating head and neck tumour cells

https://doi.org/10.18632/oncotarget.11159

Arutha Kulasinghe, Chris Perry, Majid E. Warkiani, Tony Blick, Anthony Davies, Ken O'Byrne, Erik W. Thompson, Colleen C. Nelson, Ian Vela,  and Chamindie Punyadeera
60101-60109
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The truncated somatostatin receptor sst5TMD4 stimulates the angiogenic process and is associated to lymphatic metastasis and disease-free survival in breast cancer patients

The truncated somatostatin receptor sst5TMD4 stimulates the angiogenic process and is associated to lymphatic metastasis and disease-free survival in breast cancer patients

https://doi.org/10.18632/oncotarget.11076

Manuel D. Gahete, David Rincón-Fernández, Mario Durán-Prado, Marta Hergueta-Redondo, Alejandro Ibáñez-Costa, Alejandro Rojo-Sebastián, Francisco Gracia-Navarro, Michael D. Culler, Oriol Casanovas, Gema Moreno-Bueno, Raúl M. Luque,  and Justo P. Castaño
60110-60122
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SC79 protects retinal pigment epithelium cells from UV radiation via activating Akt-Nrf2 signaling

SC79 protects retinal pigment epithelium cells from UV radiation via activating Akt-Nrf2 signaling

https://doi.org/10.18632/oncotarget.11164

Yi-qing Gong, Wei Huang, Ke-ran Li, Yuan-yuan Liu, Guo-fan Cao, Cong Cao,  and Qin Jiang
60123-60132
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Glypican-3 induces a mesenchymal to epithelial transition in human breast cancer cells

Glypican-3 induces a mesenchymal to epithelial transition in human breast cancer cells

https://doi.org/10.18632/oncotarget.11107

Lilian Fedra Castillo, Rocío Tascón, María Amparo Lago Huvelle, Gisela Novack, María Candelaria Llorens, Ancely Ferreira dos Santos, Jorge Shortrede, Ana María Cabanillas, Elisa Bal de Kier Joffé, Leticia Labriola,  and María Giselle Peters
60133-60154
Abstract  |  PDF  |  HTML  |  Order a Reprint

The miR-223 host non-coding transcript linc-223 induces IRF4 expression in acute myeloid leukemia by acting as a competing endogenous RNA

The miR-223 host non-coding transcript linc-223 induces IRF4 expression in acute myeloid leukemia by acting as a competing endogenous RNA

https://doi.org/10.18632/oncotarget.11165

Arianna Mangiavacchi, Melissa Sorci, Silvia Masciarelli, Simone Larivera, Ivano Legnini, Ilaria Iosue, Irene Bozzoni, Francesco Fazi,  and Alessandro Fatica
60155-60168
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Superior efficacy of co-treatment with the dual PI3K/mTOR inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A against NSCLC

Superior efficacy of co-treatment with the dual PI3K/mTOR inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A against NSCLC

https://doi.org/10.18632/oncotarget.11109

Junjie Piao, Liyan Chen, Taihao Quan, Longshan Li, Chunji Quan, Yingshi Piao, Tiefeng Jin,  and Zhenhua Lin
60169-60180
Abstract  |  PDF  |  HTML  |  Order a Reprint

Suppression of c-Myc and RRM2 expression in pancreatic cancer cells by the sphingosine kinase-2 inhibitor ABC294640

Suppression of c-Myc and RRM2 expression in pancreatic cancer cells by the sphingosine kinase-2 inhibitor ABC294640

https://doi.org/10.18632/oncotarget.11112

Clayton S. Lewis, Christina Voelkel-Johnson,  and Charles D. Smith
60181-60192
Abstract  |  PDF  |  HTML  |  Order a Reprint

Site-specific associations between miRNA expression and survival in colorectal cancer cases

Site-specific associations between miRNA expression and survival in colorectal cancer cases

https://doi.org/10.18632/oncotarget.11173

Martha L. Slattery, Jennifer S. Herrick, Daniel F. Pellatt, Lila E. Mullany, John R. Stevens, Erica Wolff, Michael D. Hoffman, Roger K. Wolff,  and Wade Samowitz
60193-60205
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Involvement of urokinase receptor in the cross-talk between human hematopoietic stem cells and bone marrow microenvironment

Involvement of urokinase receptor in the cross-talk between human hematopoietic stem cells and bone marrow microenvironment

https://doi.org/10.18632/oncotarget.11115

Carmine Selleri, Nunzia Montuori, Annamaria Salvati, Bianca Serio, Ada Pesapane, Patrizia Ricci, Anna Gorrasi, Anna Li Santi, Gunilla Hoyer-Hansen,  and Pia Ragno
60206-60217
Abstract  |  PDF  |  HTML  |  Order a Reprint

DNA aneuploidy and breast cancer: a meta-analysis of 141,163 cases

DNA aneuploidy and breast cancer: a meta-analysis of 141,163 cases

https://doi.org/10.18632/oncotarget.11130

Jing Xu, Lei Huang,  and Jun Li
60218-60229
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-126 inhibits colon cancer cell proliferation and invasion by targeting the chemokine (C-X-C motif) receptor 4 and Ras homolog gene family, member A, signaling pathway

MicroRNA-126 inhibits colon cancer cell proliferation and invasion by targeting the chemokine (C-X-C motif) receptor 4 and Ras homolog gene family, member A, signaling pathway

https://doi.org/10.18632/oncotarget.11176

Wei Yuan, Ye-Qing Guo, Xia-Yu Li, Min-Zi Deng, Zhao-Hua Shen, Chi-Bin Bo, Ya-Fei Dai, Ming-Yu Huang, Zhen-Yu Yang, Yong-Sheng Quan, Li Tian,  and Xiaoyan Wang
60230-60244
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sensitivity to PRIMA-1MET is associated with decreased MGMT in human glioblastoma cells and glioblastoma stem cells irrespective of p53 status

Sensitivity to PRIMA-1MET is associated with decreased MGMT in human glioblastoma cells and glioblastoma stem cells irrespective of p53 status

https://doi.org/10.18632/oncotarget.11197

Mariia Patyka, Zeinab Sharifi, Kevin Petrecca, Jose Mansure, Bertrand Jean-Claude,  and Siham Sabri
60245-60269
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Systematic revelation of the protective effect and mechanism of Cordycep sinensis on diethylnitrosamine-induced rat hepatocellular carcinoma with proteomics

Systematic revelation of the protective effect and mechanism of Cordycep sinensis on diethylnitrosamine-induced rat hepatocellular carcinoma with proteomics

https://doi.org/10.18632/oncotarget.11201

Pei-Wen Wang, Yu-Chiang Hung, Wen-Tai Li, Chau-Ting Yeh,  and Tai-Long Pan
60270-60289
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression of KLF4 promotes cell senescence through microRNA-203-survivin-p21 pathway

Overexpression of KLF4 promotes cell senescence through microRNA-203-survivin-p21 pathway

https://doi.org/10.18632/oncotarget.11200

Qing Xu, Mei Liu, Ju Zhang, Liyan Xue, Guo Zhang, Chenfei Hu, Zaozao Wang, Shun He, Lechuang Chen, Kai Ma, Xianghe Liu, Yahui Zhao, Ning Lv, Shufang Liang, Hongxia Zhu,  and Ningzhi Xu
60290-60302
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-155 and its functional variant rs767649 contribute to the susceptibility and survival of hepatocellular carcinoma

MiR-155 and its functional variant rs767649 contribute to the susceptibility and survival of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.11206

Jiansong Ji, Min Xu, Jianfei Tu, Zhongwei Zhao, Jun Gao, Minjiang Chen, Jingjing Song, Haidong Zhu, Xingyao Cheng, Junguo Hui, Xilin Lan,  and Xiaoming Yang
60303-60309
Abstract  |  PDF  |  HTML  |  Order a Reprint

Wnt signalling is a bi-directional vulnerability of cancer cells

Wnt signalling is a bi-directional vulnerability of cancer cells

https://doi.org/10.18632/oncotarget.11203

David J. Duffy, Aleksandar Krstic, Thomas Schwarzl, Melinda Halasz, Kristiina Iljin, Dirk Fey, Bridget Haley, Jenny Whilde, Saija Haapa-Paananen, Vidal Fey, Matthias Fischer, Frank Westermann, Kai-Oliver Henrich, Steffen Bannert, Desmond G. Higgins,  and Walter Kolch
60310-60331
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ephrin B3 interacts with multiple EphA receptors and drives migration and invasion in non-small cell lung cancer

Ephrin B3 interacts with multiple EphA receptors and drives migration and invasion in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.11219

Ghazal Efazat, Metka Novak, Vitaliy O. Kaminskyy, Luigi De Petris, Lena Kanter, Therese Juntti, Per Bergman, Boris Zhivotovsky, Rolf Lewensohn, Petra Hååg,  and Kristina Viktorsson
60332-60347
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Proteomic identification of cyclophilin A as a potential biomarker and therapeutic target in oral submucous fibrosis

Proteomic identification of cyclophilin A as a potential biomarker and therapeutic target in oral submucous fibrosis

https://doi.org/10.18632/oncotarget.11254

Yao Yuan, Xiaohui Hou, Hui Feng, Rui Liu, Hao Xu, Wang Gong, Jing Deng, Chongkui Sun, Yijun Gao, Jieying Peng, Yingfang Wu, Jiang Li, Changyun Fang,  and Qianming Chen
60348-60365
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Acetylation of FOXM1 is essential for its transactivation and tumor growth stimulation

Acetylation of FOXM1 is essential for its transactivation and tumor growth stimulation

https://doi.org/10.18632/oncotarget.11332

Cuicui Lv, Ganye Zhao, Xinpei Sun, Pan Wang, Nan Xie, Jianyuan Luo,  and Tanjun Tong
60366-60382
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Spatial distribution of FoxP3+ and CD8+ tumour infiltrating T cells reflects their functional activity

Spatial distribution of FoxP3+ and CD8+ tumour infiltrating T cells reflects their functional activity

https://doi.org/10.18632/oncotarget.11039

Rebecca Posselt, Katharina Erlenbach-Wünsch, Matthias Haas, Jonas Jeßberger, Maike Büttner-Herold, Marlen Haderlein, Markus Hecht, Arndt Hartmann, Rainer Fietkau,  and Luitpold V. Distel
60383-60394
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oncostatin M suppresses metastasis of lung adenocarcinoma by inhibiting SLUG expression through coordination of STATs and PIASs signalings

Oncostatin M suppresses metastasis of lung adenocarcinoma by inhibiting SLUG expression through coordination of STATs and PIASs signalings

https://doi.org/10.18632/oncotarget.10939

Chih-Ming Pan, Mong-Lien Wang, Shih-Hwa Chiou, Hsiao-Yun Chen,  and Cheng-Wen Wu
60395-60406
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Lin28A activates androgen receptor via regulation of c-myc and promotes malignancy of ER−/Her2+ breast cancer

Lin28A activates androgen receptor via regulation of c-myc and promotes malignancy of ER−/Her2+ breast cancer

https://doi.org/10.18632/oncotarget.11004

Honghong Shen, Lin Zhao, Xiaolong Feng, Cong Xu, Congying Li,  and Yun Niu
60407-60418
Abstract  |  PDF  |  HTML  |  Order a Reprint

Smoking, second-hand smoke exposure and smoking cessation in relation to leukocyte telomere length and mortality

Smoking, second-hand smoke exposure and smoking cessation in relation to leukocyte telomere length and mortality

https://doi.org/10.18632/oncotarget.11051

Wahyu Wulaningsih, Fidel Emmanuel C. Serrano, Adi Utarini, Tetsuya Matsuguchi, Johnathan Watkins,  and for PILAR Research Network
60419-60431
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Radiation induces premature chromatid separation via the miR-142-3p/Bod1 pathway in carcinoma cells

Radiation induces premature chromatid separation via the miR-142-3p/Bod1 pathway in carcinoma cells

https://doi.org/10.18632/oncotarget.11080

Dong Pan, Yarong Du, Zhenxin Ren, Yaxiong Chen, Xiaoman Li, Jufang Wang,  and Burong Hu
60432-60445
Abstract  |  PDF  |  HTML  |  Order a Reprint

Chemoprevention of intestinal tumorigenesis by the natural dietary flavonoid myricetin in APCMin/+ mice

Chemoprevention of intestinal tumorigenesis by the natural dietary flavonoid myricetin in APCMin/+ mice

https://doi.org/10.18632/oncotarget.11108

Ye Li, Shu-Xiang Cui, Shi-Yue Sun, Wen-Na Shi, Zhi-Yu Song, Shu-Qing Wang, Xin-Feng Yu, Zu-Hua Gao,  and Xian-Jun Qu
60446-60460
Abstract  |  PDF  |  HTML  |  Order a Reprint

IL-2 augments the therapeutic efficacy of adoptively transferred B cells which directly kill tumor cells via the CXCR4/CXCL12 and perforin pathways

IL-2 augments the therapeutic efficacy of adoptively transferred B cells which directly kill tumor cells via the CXCR4/CXCL12 and perforin pathways

https://doi.org/10.18632/oncotarget.11124

Yang Xia, Huimin Tao, Yangyang Hu, Quanning Chen, Xin Chen, Leiming Xia, Li Zhou, Yi Wang, Yangyi Bao, Shiang Huang, Xiubao Ren, Steven K. Lundy, Fu Dai, Qiao Li,  and Alfred E. Chang
60461-60474
Abstract  |  PDF  |  HTML  |  Order a Reprint

A single nucleotide polymorphism genotyping platform for the authentication of patient derived xenografts

A single nucleotide polymorphism genotyping platform for the authentication of patient derived xenografts

https://doi.org/10.18632/oncotarget.11125

Jad El-Hoss, Duohui Jing, Kathryn Evans, Cara Toscan, Jinhan Xie, Hyunjoo Lee, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Karen L. MacKenzie, Rosemary Sutton,  and Richard B. Lock
60475-60490
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

An oncolytic adenovirus that expresses the HAb18 and interleukin 24 genes exhibits enhanced antitumor activity in hepatocellular carcinoma cells

An oncolytic adenovirus that expresses the HAb18 and interleukin 24 genes exhibits enhanced antitumor activity in hepatocellular carcinoma cells

https://doi.org/10.18632/oncotarget.11134

Sujing Yuan, Xianlong Fang, Aimin Ni, Xin-Yuan Liu,  and Liang Chu
60491-60502
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of androgen-responsive lncRNAs as diagnostic and prognostic markers for prostate cancer

Identification of androgen-responsive lncRNAs as diagnostic and prognostic markers for prostate cancer

https://doi.org/10.18632/oncotarget.11391

Xuechao Wan, Wenhua Huang, Shu Yang, Yalong Zhang, Honglei Pu, Fangqiu Fu, Yan Huang, Hai Wu, Tao Li,  and Yao Li
60503-60518
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

USP9X destabilizes pVHL and promotes cell proliferation

USP9X destabilizes pVHL and promotes cell proliferation

https://doi.org/10.18632/oncotarget.11139

Cong Zhang, Zuohan Peng, Minglu Zhu, Penglong Wang, Xiao Du, Xiang Li, Yu Liu, Yan Jin, Michael A. McNutt,  and Yuxin Yin
60519-60534
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Waking up dormant tumor suppressor genes with zinc fingers, TALEs and the CRISPR/dCas9 system

Waking up dormant tumor suppressor genes with zinc fingers, TALEs and the CRISPR/dCas9 system

https://doi.org/10.18632/oncotarget.11142

Benjamin Garcia-Bloj, Colette Moses, Agustin Sgro, Janice Plani-Lam, Mahira Arooj, Ciara Duffy, Shreyas Thiruvengadam, Anabel Sorolla, Rabab Rashwan, Ricardo L. Mancera, Andrea Leisewitz, Theresa Swift-Scanlan, Alejandro H. Corvalan,  and Pilar Blancafort
60535-60554
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Evaluation of DNMT3A genetic polymorphisms as outcome predictors in AML patients

Evaluation of DNMT3A genetic polymorphisms as outcome predictors in AML patients

https://doi.org/10.18632/oncotarget.11143

Xiao-Qing Yuan, Dao-Yu Zhang, Han Yan, Yong-Long Yang, Ke-Wei Zhu, Yan-Hong Chen, Xi Li, Ji-Ye Yin, Xiao-Lin Li, Hui Zeng,  and Xiao-Ping Chen
60555-60574
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of glucosylceramide synthase eliminates the oncogenic function of p53 R273H mutant in the epithelial-mesenchymal transition and induced pluripotency of colon cancer cells

Inhibition of glucosylceramide synthase eliminates the oncogenic function of p53 R273H mutant in the epithelial-mesenchymal transition and induced pluripotency of colon cancer cells

https://doi.org/10.18632/oncotarget.11169

Salman B. Hosain, Sachin K. Khiste, Mohammad B. Uddin, Vindya Vorubindi, Catherine Ingram, Sifang Zhang, Ronald A. Hill, Xin Gu,  and Yong-Yu Liu
60575-60592
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Downregulation of homeobox gene Barx2 increases gastric cancer proliferation and metastasis and predicts poor patient outcomes

Downregulation of homeobox gene Barx2 increases gastric cancer proliferation and metastasis and predicts poor patient outcomes

https://doi.org/10.18632/oncotarget.11260

Yushuai Mi, Senlin Zhao, Chongzhi Zhou, Junyong Weng, Jikun Li, Zhanshan Wang, Huimin Sun, Huamei Tang, Xin Zhang, Xiaofeng Sun, Zhihai Peng,  and Yugang Wen
60593-60608
Abstract  |  PDF  |  HTML  |  Order a Reprint

Activated platelets inhibit hepatocellular carcinoma cell differentiation and promote tumor progression via platelet-tumor cell binding

Activated platelets inhibit hepatocellular carcinoma cell differentiation and promote tumor progression via platelet-tumor cell binding

https://doi.org/10.18632/oncotarget.11300

Rongfeng Zhang, Huishu Guo, Jingchao Xu, Bing Li, Yue-Jian Liu, Cheng Cheng, Chunyan Zhou, Yongfu Zhao,  and Yang Liu
60609-60622
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CD151-mediated adhesion is crucial to osteosarcoma pulmonary metastasis

CD151-mediated adhesion is crucial to osteosarcoma pulmonary metastasis

https://doi.org/10.18632/oncotarget.11380

Zhuoying Wang, Chongren Wang, Zifei Zhou, Mengxiong Sun, Chenghao Zhou, Jian Chen, Fei Yin, Hongsheng Wang, Binhui Lin, Dongqing Zuo, Suoyuan Li, Lijin Feng, Zhenfeng Duan, Zhengdong Cai,  and Yingqi Hua
60623-60638
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Clinical significance of post-surgical residual tumor burden and radiation therapy in treating patients with lacrimal adenoid cystic carcinoma

Clinical significance of post-surgical residual tumor burden and radiation therapy in treating patients with lacrimal adenoid cystic carcinoma

https://doi.org/10.18632/oncotarget.10259

Jae Myoung Noh, Eonju Lee, Yong Chan Ahn, Dongryul Oh, Yoon-Duck Kim, Kyung In Woo, Young-Hyeh Ko,  and Seokhwi Kim
60639-60646
Abstract  |  PDF  |  HTML  |  Order a Reprint

Better pathologic complete response and relapse-free survival after carboplatin plus paclitaxel compared with epirubicin plus paclitaxel as neoadjuvant chemotherapy for locally advanced triple-negative breast cancer: a randomized phase 2 trial

Better pathologic complete response and relapse-free survival after carboplatin plus paclitaxel compared with epirubicin plus paclitaxel as neoadjuvant chemotherapy for locally advanced triple-negative breast cancer: a randomized phase 2 trial

https://doi.org/10.18632/oncotarget.10607

Pin Zhang, Yi Yin, Hongnan Mo, Bailin Zhang, Xiang Wang, Qing Li, Peng Yuan, Jiayu Wang, Shan Zheng, Ruigang Cai, Fei Ma, Yin Fan,  and Binghe Xu
60647-60656
Abstract  |  PDF  |  HTML  |  Order a Reprint

Increased expression of αTubulin is associated with poor prognosis in patients with pancreatic cancer after surgical resection

Increased expression of αTubulin is associated with poor prognosis in patients with pancreatic cancer after surgical resection

https://doi.org/10.18632/oncotarget.10630

Chao Lin, Guo-chao Zhao, Ya-dong Xu, Dan-song Wang, Da-yong Jin, Yuan Ji, Wen-hui Lou,  and Wen-chuan Wu
60657-60664
Abstract  |  PDF  |  HTML  |  Order a Reprint

Treatment of primary intracranial germ cell tumors: Single center experience with 42 clinically diagnosed cases

Treatment of primary intracranial germ cell tumors: Single center experience with 42 clinically diagnosed cases

https://doi.org/10.18632/oncotarget.10218

Qun-Ying Yang, Cheng-Cheng Guo, Mei-Ling Deng, Jian Wang, Jing Wang, Fu-hua Lin, Ji Zhang, Xiao-Bing Jiang, Yong-Gao Mou,  and Zhong-Ping Chen
60665-60675
Abstract  |  PDF  |  HTML  |  Order a Reprint

Leukocyte mitochondrial DNA copy number, anthropometric indices, and weight change in US women

Leukocyte mitochondrial DNA copy number, anthropometric indices, and weight change in US women

https://doi.org/10.18632/oncotarget.10325

Shasha Meng, Shaowei Wu, Liming Liang, Geyu Liang, Edward Giovannucci, Immaculata De Vivo,  and Hongmei Nan
60676-60686
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Reviews

Exosomes: small vesicles with big roles in hepatocellular carcinoma

Exosomes: small vesicles with big roles in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.10807

Zhitong Wu, Qinghai Zeng, Ke Cao,  and Yifan Sun
60687-60697
Abstract  |  PDF  |  HTML  |  Order a Reprint

Microenvironment drug resistance in multiple myeloma: emerging new players

Microenvironment drug resistance in multiple myeloma: emerging new players

https://doi.org/10.18632/oncotarget.10849

Lucia Di Marzo, Vanessa Desantis, Antonio Giovanni Solimando, Simona Ruggieri, Tiziana Annese, Beatrice Nico, Ruggiero Fumarulo, Angelo Vacca,  and Maria Antonia Frassanito
60698-60711
Abstract  |  PDF  |  HTML  |  Order a Reprint

Triple negative breast cancer: shedding light onto the role of pi3k/akt/mtor pathway

Triple negative breast cancer: shedding light onto the role of pi3k/akt/mtor pathway

https://doi.org/10.18632/oncotarget.10858

Daniela Massihnia, Antonio Galvano, Daniele Fanale, Alessandro Perez, Marta Castiglia, Lorena Incorvaia, Angela Listì, Sergio Rizzo, Giuseppe Cicero, Viviana Bazan, Sergio Castorina,  and Antonio Russo
60712-60722
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Role of micro-RNAs in drug resistance of multiple myeloma

Role of micro-RNAs in drug resistance of multiple myeloma

https://doi.org/10.18632/oncotarget.11032

Jahangir Abdi, Hou Jian,  and Hong Chang
60723-60735
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The functions and clinical applications of tumor-derived exosomes

The functions and clinical applications of tumor-derived exosomes

https://doi.org/10.18632/oncotarget.11177

Yingkuan Shao, Yanwei Shen, Ting Chen, Fei Xu, Xuewen Chen,  and Shu Zheng
60736-60751
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Mesenchymal stromal cells (MSCs) and colorectal cancer: a troublesome twosome for the anti-tumour immune response?

Mesenchymal stromal cells (MSCs) and colorectal cancer: a troublesome twosome for the anti-tumour immune response?

https://doi.org/10.18632/oncotarget.11354

Grace O’Malley, Madelon Heijltjes, Aileen M. Houston, Sweta Rani, Thomas Ritter, Laurence J. Egan,  and Aideen E. Ryan
60752-60774
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Corrections

Correction: Perlecan/HSPG2 and matrilysin/MMP-7 as indices of tissue invasion: tissue localization and circulating perlecan fragments in a cohort of 288 radical prostatectomy patients

Correction: Perlecan/HSPG2 and matrilysin/MMP-7 as indices of tissue invasion: tissue localization and circulating perlecan fragments in a cohort of 288 radical prostatectomy patients

https://doi.org/10.18632/oncotarget.11976

Brian Grindel, Quanlin Li, Rebecca Arnold, John Petros, Majd Zayzafoon, Mark Muldoon, James Stave, Leland W.K. Chung,  and Mary C. Farach-Carson
60775-60775
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