Oncotarget

Vol 7, No 33

August 16, 2016

View Archive »

Order a Reprint

About The Cover

The cover for issue 33 of Oncotarget features Figure 6B (FAK/AKT signaling is not altered upon lower pelvis irradiation and JNK inhibition in β1wt /TRAMP mice) from Sayeed et al.

Table of Contents

Research Perspectives

CALR mutation characterization in myeloproliferative neoplasms

CALR mutation characterization in myeloproliferative neoplasms

https://doi.org/10.18632/oncotarget.10376

Cristina Bilbao-Sieyro, Yanira Florido,  and María Teresa Gómez-Casares
52614-52617
Abstract  |  PDF  |  HTML  |  Order a Reprint

Priority Research Papers

β1 integrin- and JNK-dependent tumor growth upon hypofractionated radiation

β1 integrin- and JNK-dependent tumor growth upon hypofractionated radiation

https://doi.org/10.18632/oncotarget.10522

Aejaz Sayeed, Huimin Lu, Qin Liu, David Deming II, Alexander Duffy, Peter McCue, Adam P. Dicker, Roger J. Davis, Dmitry Gabrilovich, Ulrich Rodeck, Dario C. Altieri,  and Lucia R. Languino
52618-52630
Abstract  |  PDF  |  HTML  |  Order a Reprint

Troponin-I enhances and is required for oncogenic overgrowth

Troponin-I enhances and is required for oncogenic overgrowth

https://doi.org/10.18632/oncotarget.10616

Sergio Casas-Tintó, Antonio Maraver, Manuel Serrano,  and Alberto Ferrús
52631-52642
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

p53 elevation in human cells halt SV40 infection by inhibiting T-ag expression

p53 elevation in human cells halt SV40 infection by inhibiting T-ag expression

https://doi.org/10.18632/oncotarget.10769

Nir Drayman, Orly Ben-nun-Shaul, Veronika Butin-Israeli, Rohit Srivastava, Ariel M. Rubinstein, Caroline S. Mock, Ela Elyada, Yinon Ben-Neriah, Galit Lahav,  and Ariella Oppenheim
52643-52660
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Priority Research Papers: Pathology

Agonistic analogs of growth hormone releasing hormone (GHRH) promote wound healing by stimulating the proliferation and survival of human dermal fibroblasts through ERK and AKT pathways

Agonistic analogs of growth hormone releasing hormone (GHRH) promote wound healing by stimulating the proliferation and survival of human dermal fibroblasts through ERK and AKT pathways

https://doi.org/10.18632/oncotarget.11024

Tengjiao Cui, Joaquin J. Jimenez, Norman L. Block, Evangelos V. Badiavas, Luis Rodriguez-Menocal, Ailin Vila Granda, Renzhi Cai, Wei Sha, Marta Zarandi, Roberto Perez,  and Andrew V. Schally
52661-52672
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers: Gerotarget (Focus on Aging)

Identification of the lncRNA, AK156230, as a novel regulator of cellular senescence in mouse embryonic fibroblasts

Identification of the lncRNA, AK156230, as a novel regulator of cellular senescence in mouse embryonic fibroblasts

https://doi.org/10.18632/oncotarget.10170

Yu-ning Chen, Meng-yun Cai, Shun Xu, Mei Meng, ingcong Ren, Jay W. Yang, Yu-qi Dong, Xinguang Liu, Jin-Ming Yang,  and Xing-dong Xiong
52673-52684
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The underlying mechanism of proinflammatory NF-κB activation by the mTORC2/Akt/IKKα pathway during skin aging

The underlying mechanism of proinflammatory NF-κB activation by the mTORC2/Akt/IKKα pathway during skin aging

https://doi.org/10.18632/oncotarget.10943

Yeon Ja Choi, Kyoung Mi Moon, Ki Wung Chung, Ji Won Jeong, Daeui Park, Dae Hyun Kim, Byung Pal Yu,  and Hae Young Chung
52685-52694
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Idiopathic chronic fatigue in older adults is linked to impaired mitochondrial content and biogenesis signaling in skeletal muscle

Idiopathic chronic fatigue in older adults is linked to impaired mitochondrial content and biogenesis signaling in skeletal muscle

https://doi.org/10.18632/oncotarget.10685

Nicholas R. Wawrzyniak, Anna-Maria Joseph, David G. Levin, David M. Gundermann, Christiaan Leeuwenburgh, Bhanuprasad Sandesara, Todd M. Manini,  and Peter J. Adhihetty
52695-52709
Abstract  |  PDF  |  HTML  |  Order a Reprint

Research Papers: Pathology

Stimulatory actions of IGF-I are mediated by IGF-IR cross-talk with GPER and DDR1 in mesothelioma and lung cancer cells

Stimulatory actions of IGF-I are mediated by IGF-IR cross-talk with GPER and DDR1 in mesothelioma and lung cancer cells

https://doi.org/10.18632/oncotarget.10348

Silvia Avino, Paola De Marco, Francesca Cirillo, Maria Francesca Santolla, Ernestina Marianna De Francesco, Maria Grazia Perri, Damiano Rigiracciolo, Vincenza Dolce, Antonino Belfiore, Marcello Maggiolini, Rosamaria Lappano,  and Adele Vivacqua
52710-52728
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activation of activator protein 2 alpha by aspirin alleviates atherosclerotic plaque growth and instability in vivo

Activation of activator protein 2 alpha by aspirin alleviates atherosclerotic plaque growth and instability in vivo

https://doi.org/10.18632/oncotarget.10400

Jing-Jing Yang, Peng Li, Fu Wang, Wen-Jing Liang, Hui Ma, Yuan Chen, Zhi-Min Ma, Quan-Zhong Li, Qi-Sheng Peng, Yun Zhang,  and Shuang-Xi Wang
52729-52739
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association of genetic variations in the Wnt signaling pathway genes with myocardial infarction susceptibility in Chinese Han population

Association of genetic variations in the Wnt signaling pathway genes with myocardial infarction susceptibility in Chinese Han population

https://doi.org/10.18632/oncotarget.10401

Jing Tao, Yong-tao Wang, Mayila Abudoukelimu, Yi-ning Yang, Xiao-mei Li, Xiang Xie, Bang-dang Chen, Fen Liu, Chun-hui He, Hua-yin Li,  and Yi-tong Ma
52740-52750
Abstract  |  PDF  |  HTML  |  Order a Reprint

Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer

Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer

https://doi.org/10.18632/oncotarget.10481

Jessica Gasca, Maria Luz Flores, Servando Giráldez, Manuel Ruiz-Borrego, María Tortolero, Francisco Romero, Miguel A. Japón,  and Carmen Sáez
52751-52765
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

In silico predicted structural and functional insights of all missense mutations on 2B domain of K1/K10 causing genodermatoses

In silico predicted structural and functional insights of all missense mutations on 2B domain of K1/K10 causing genodermatoses

https://doi.org/10.18632/oncotarget.10599

Santasree Banerjee, Qian Wu, Yuyi Ying, Yanni Li, Matsuyuki Shirota, Dante Neculai,  and Chen Li
52766-52780
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Integrated analysis miRNA and mRNA profiling in patients with severe oligozoospermia reveals miR-34c-3p downregulates PLCXD3 expression

Integrated analysis miRNA and mRNA profiling in patients with severe oligozoospermia reveals miR-34c-3p downregulates PLCXD3 expression

https://doi.org/10.18632/oncotarget.10947

Zhiming Li, Zaozao Zheng, Jun Ruan, Zhi Li, Xuan Zhuang,  and Chi-Meng Tzeng
52781-52796
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers: Immunology

Coumestrol inhibits autoantibody production through modulating Th1 response in experimental autoimmune thyroiditis

Coumestrol inhibits autoantibody production through modulating Th1 response in experimental autoimmune thyroiditis

https://doi.org/10.18632/oncotarget.10353

Xiaojing Jin, Shujun Wang, Xuemin Zhao, Qian Jin, Chenling Fan, Jing Li, Zhongyan Shan,  and Weiping Teng
52797-52809
Abstract  |  PDF  |  HTML  |  Order a Reprint

Early evidence of anti-PD-1 activity in enzalutamide-resistant prostate cancer

Early evidence of anti-PD-1 activity in enzalutamide-resistant prostate cancer

https://doi.org/10.18632/oncotarget.10547

Julie N. Graff, Joshi J. Alumkal, Charles G. Drake, George V. Thomas, William L. Redmond, Mohammad Farhad, Jeremy P. Cetnar, Frederick S. Ey, Raymond C. Bergan, Rachel Slottke,  and Tomasz M. Beer
52810-52817
Abstract  |  PDF  |  HTML  |  Order a Reprint

Minocycline promotes the generation of dendritic cells with regulatory properties

Minocycline promotes the generation of dendritic cells with regulatory properties

https://doi.org/10.18632/oncotarget.10810

Narae Kim, Chan-Su Park, Sun-A Im, Ji-Wan Kim, Jae-Hee Lee, Young-Jun Park, Sukgil Song,  and Chong-Kil Lee
52818-52831
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers: Autophagy and Cell Death

Gelsolin-Cu/ZnSOD interaction alters intracellular reactive oxygen species levels to promote cancer cell invasion

Gelsolin-Cu/ZnSOD interaction alters intracellular reactive oxygen species levels to promote cancer cell invasion

https://doi.org/10.18632/oncotarget.10451

Lalchhandami Tochhawng, Shuo Deng, Ganesan Pugalenthi, Alan Prem Kumar, Kiat Hon Lim, Tuan Zea Tan, Henry Yang, Shing Chuan Hooi, Yaw Chong Goh, Sutherland K. Maciver, Shazib Pervaiz,  and Celestial T. Yap
52832-52848
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Analysis of the immune microenvironment in resected non-small cell lung cancer: the prognostic value of different T lymphocyte markers

Analysis of the immune microenvironment in resected non-small cell lung cancer: the prognostic value of different T lymphocyte markers

https://doi.org/10.18632/oncotarget.10811

Marta Usó, Eloisa Jantus-Lewintre, Roy M. Bremnes, Silvia Calabuig, Ana Blasco, Enrique Pastor, Irene Borreda, Sonia Molina-Pinelo, Luis Paz-Ares, Ricardo Guijarro, Miguel Martorell, Jerónimo Forteza, Carlos Camps,  and Rafael Sirera
52849-52861
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers

Overexpression of mutant EGFR protein indicates a better survival benefit from EGFR-TKI therapy in non-small cell lung cancer

Overexpression of mutant EGFR protein indicates a better survival benefit from EGFR-TKI therapy in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.10594

Yun Ling, Xin Yang, Wenbin Li, Zhuo Li, Lin Yang, Tian Qiu, Lei Guo, Lin Dong, Lin Li, Jianming Ying,  and Dongmei Lin
52862-52869
Abstract  |  PDF  |  HTML  |  Order a Reprint

KLF4 downregulates hTERT expression and telomerase activity to inhibit lung carcinoma growth

KLF4 downregulates hTERT expression and telomerase activity to inhibit lung carcinoma growth

https://doi.org/10.18632/oncotarget.9141

Wenxian Hu, Yunlu Jia, Xiangsheng Xiao, Kezhen Lv, Yongxia Chen, Linbo Wang, Xiao Luo, Tianze Liu, Wenbin Li, Yixin Li, Changlin Zhang, Zhenglong Yu, Wenlin Huang, Bing Sun,  and Wu-guo Deng
52870-52887
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A comparative assessment of clinical whole exome and transcriptome profiling across sequencing centers: implications for precision cancer medicine

A comparative assessment of clinical whole exome and transcriptome profiling across sequencing centers: implications for precision cancer medicine

https://doi.org/10.18632/oncotarget.9184

Eliezer M. Van Allen, Dan Robinson, Colm Morrissey, Colin Pritchard, Alma Imamovic, Scott Carter, Mara Rosenberg, Aaron McKenna, Yi-Mi Wu, Xuhong Cao, Arul Chinnaiyan, Levi Garraway,  and Peter S. Nelson
52888-52899
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IDO1 involvement in mTOR pathway: a molecular mechanism of resistance to mTOR targeting in medulloblastoma

IDO1 involvement in mTOR pathway: a molecular mechanism of resistance to mTOR targeting in medulloblastoma

https://doi.org/10.18632/oncotarget.9284

Valentina Folgiero, Evelina Miele, Andrea Carai, Elisabetta Ferretti, Vincenzo Alfano, Agnese Po, Valentina Bertaina, Bianca Maria Goffredo, Maria Chiara Benedetti, Francesca Diomedi Camassei, Antonella Cacchione, Franco Locatelli,  and Angela Mastronuzzi
52900-52911
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Modulation of miR-21 signaling by MPS1 in human glioblastoma

Modulation of miR-21 signaling by MPS1 in human glioblastoma

https://doi.org/10.18632/oncotarget.4143

Uday B. Maachani, Anita Tandle, Uma Shankavaram, Tamalee Kramp,  and Kevin A. Camphausen
52912-52927
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Repurposing the anti-malarial drug, quinacrine: new anti-colitis properties

Repurposing the anti-malarial drug, quinacrine: new anti-colitis properties

https://doi.org/10.18632/oncotarget.10608

Alexander A. Chumanevich, Erin E. Witalison, Anusha Chaparala, Anastasiya Chumanevich, Prakash Nagarkatti, Mitzi Nagarkatti,  and Lorne J. Hofseth
52928-52939
Abstract  |  PDF  |  HTML  |  Order a Reprint

FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures

FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures

https://doi.org/10.18632/oncotarget.9507

Kah Keng Wong, Duncan M. Gascoyne, Elizabeth J. Soilleux, Linden Lyne, Hayley Spearman, Giovanna Roncador, Lars M. Pedersen, Michael B. Møller, Tina M. Green,  and Alison H. Banham
52940-52956
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Consensus of gene expression phenotypes and prognostic risk predictors in primary lung adenocarcinoma

Consensus of gene expression phenotypes and prognostic risk predictors in primary lung adenocarcinoma

https://doi.org/10.18632/oncotarget.10641

Markus Ringnér,  and Johan Staaf
52957-52973
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Germline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based “starvation” strategies in BRCA1 carriers

Germline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based “starvation” strategies in BRCA1 carriers

https://doi.org/10.18632/oncotarget.9732

Elisabet Cuyàs, Salvador Fernández-Arroyo, Tomás Alarcón, Ruth Lupu, Jorge Joven,  and Javier A. Menendez
52974-52992
Abstract  |  PDF  |  HTML  |  Order a Reprint

Inducible nitric oxide synthase enhances disease aggressiveness in pancreatic cancer

Inducible nitric oxide synthase enhances disease aggressiveness in pancreatic cancer

https://doi.org/10.18632/oncotarget.10323

Jian Wang, Peijun He, Matthias Gaida, Shouhui Yang, Aaron J. Schetter, Jochen Gaedcke, B. Michael Ghadimi, Thomas Ried, Harris Yfantis, Dong Lee, Jonathan M. Weiss, Jimmy Stauffer, Nader Hanna, H. Richard Alexander,  and S. Perwez Hussain
52993-53004
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Downregulating serine hydroxymethyltransferase 2 (SHMT2) suppresses tumorigenesis in human hepatocellular carcinoma

Downregulating serine hydroxymethyltransferase 2 (SHMT2) suppresses tumorigenesis in human hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.10415

Chern Chiuh Woo, Way Cherng Chen, Xing Qi Teo, George K. Radda,  and Philip Teck Hock Lee
53005-53017
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Histone methyltransferase PRMT6 plays an oncogenic role of in prostate cancer

Histone methyltransferase PRMT6 plays an oncogenic role of in prostate cancer

https://doi.org/10.18632/oncotarget.10061

Diogo Almeida-Rios, Inês Graça, Filipa Quintela Vieira, João Ramalho-Carvalho, Eva Pereira-Silva, Ana Teresa Martins, Jorge Oliveira, Céline S. Gonçalves, Bruno M. Costa, Rui Henrique,  and Carmen Jerónimo
53018-53028
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Decreased radiation doses to tongue with “stick-out” tongue position over neutral tongue position in head and neck cancer patients who refused or could not tolerate an intraoral device (bite-block, tongue blade, or mouthpiece) due to trismus, gag reflex, or discomfort during intensity-modulated radiation therapy

Decreased radiation doses to tongue with “stick-out” tongue position over neutral tongue position in head and neck cancer patients who refused or could not tolerate an intraoral device (bite-block, tongue blade, or mouthpiece) due to trismus, gag reflex, or discomfort during intensity-modulated radiation therapy

https://doi.org/10.18632/oncotarget.10621

Whoon Jong Kil, Christina Kulasekere, Ronald Derrwaldt, Jacob Bugno,  and Craig Hatch
53029-53036
Abstract  |  PDF  |  HTML  |  Order a Reprint

An appraisal of drug development timelines in the Era of precision oncology

An appraisal of drug development timelines in the Era of precision oncology

https://doi.org/10.18632/oncotarget.10588

Denis Leonardo Jardim, Maria Schwaederle, David S. Hong,  and Razelle Kurzrock
53037-53046
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PDGFRα depletion attenuates glioblastoma stem cells features by modulation of STAT3, RB1 and multiple oncogenic signals

PDGFRα depletion attenuates glioblastoma stem cells features by modulation of STAT3, RB1 and multiple oncogenic signals

https://doi.org/10.18632/oncotarget.10132

Carlo Cenciarelli, Hany E. Marei, Armando Felsani, Patrizia Casalbore, Gigliola Sica, Maria Ausiliatrice Puglisi, Angus JM Cameron, Alessandro Olivi,  and Annunziato Mangiola
53047-53063
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia

COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.10590

Bruno Almeida Lopes, Claus Meyer, Thayana Conceição Barbosa, Udo zur Stadt, Martin Horstmann, Nicola C. Venn, Susan Heatley, Deborah L. White, Rosemary Sutton, Maria S. Pombo-de-Oliveira, Rolf Marschalek,  and Mariana Emerenciano
53064-53073
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Molecular mechanisms of OLIG2 transcription factor in brain cancer

Molecular mechanisms of OLIG2 transcription factor in brain cancer

https://doi.org/10.18632/oncotarget.10628

Igor F. Tsigelny, Valentina L. Kouznetsova, Nathan Lian,  and Santosh Kesari
53074-53101
Abstract  |  PDF  |  HTML  |  Order a Reprint

Development of a sequential workflow based on LC-PRM for the verification of endometrial cancer protein biomarkers in uterine aspirate samples

Development of a sequential workflow based on LC-PRM for the verification of endometrial cancer protein biomarkers in uterine aspirate samples

https://doi.org/10.18632/oncotarget.10632

Elena Martinez-Garcia, Antoine Lesur, Laura Devis, Alexandre Campos, Silvia Cabrera, Jan van Oostrum, Xavier Matias-Guiu, Antonio Gil-Moreno, Jaume Reventos, Eva Colas,  and Bruno Domon
53102-53115
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combination therapy with copanlisib and ABL tyrosine kinase inhibitors against Philadelphia chromosome-positive resistant cells

Combination therapy with copanlisib and ABL tyrosine kinase inhibitors against Philadelphia chromosome-positive resistant cells

https://doi.org/10.18632/oncotarget.10605

Seiichi Okabe, Tetsuzo Tauchi, Yuko Tanaka, Juri Sakuta,  and Kazuma Ohyashiki
53116-53126
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TERT promoter mutations in melanoma render TERT expression dependent on MAPK pathway activation

TERT promoter mutations in melanoma render TERT expression dependent on MAPK pathway activation

https://doi.org/10.18632/oncotarget.10634

Andrelou F. Vallarelli, P. Sivaramakrishna Rachakonda, Jocelyne André, Barbara Heidenreich, Laurence Riffaud, Armand Bensussan, Rajiv Kumar,  and Nicolas Dumaz
53127-53136
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Serotonin transporter antagonists target tumor-initiating cells in a transgenic mouse model of breast cancer

Serotonin transporter antagonists target tumor-initiating cells in a transgenic mouse model of breast cancer

https://doi.org/10.18632/oncotarget.10614

Robin M. Hallett, Adele Girgis-Gabardo, William D. Gwynne, Andrew O. Giacomelli, Jennifer N.P. Bisson, Jeremy E. Jensen, Anna Dvorkin-Gheva,  and John A. Hassell
53137-53152
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

KRASG12 mutant induces the release of the WSTF/NRG3 complex, and contributes to an oncogenic paracrine signaling pathway

KRASG12 mutant induces the release of the WSTF/NRG3 complex, and contributes to an oncogenic paracrine signaling pathway

https://doi.org/10.18632/oncotarget.10625

Yan Liu, Shu-Qing Wang, Yue-Hong Long, Su Chen, Yu-Feng Li,  and Jing-Hua Zhang
53153-53164
Abstract  |  PDF  |  HTML  |  Order a Reprint

Globally increased ultraconserved noncoding RNA expression in pancreatic adenocarcinoma

Globally increased ultraconserved noncoding RNA expression in pancreatic adenocarcinoma

https://doi.org/10.18632/oncotarget.10242

Jinmai Jiang, Ana Clara P. Azevedo-Pouly, Roxana S. Redis, Eun Joo Lee, Yuriy Gusev, David Allard, Dhruvitkumar S. Sutaria, Mohamed Badawi, Ola A. Elgamal, Megan R. Lerner, Daniel J. Brackett, George A. Calin,  and Thomas D. Schmittgen
53165-53177
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules

Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules

https://doi.org/10.18632/oncotarget.10629

Jee Hye Kim, Ye Jin Jung, Byeol Choi, Na Lim Lee, Hae Jun Lee, Soo Yeon Kwak, Youngjoo Kwon, Younghwa Na,  and Yun-Sil Lee
53178-53190
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CK2 blockade causes MPNST cell apoptosis and promotes degradation of β-catenin

CK2 blockade causes MPNST cell apoptosis and promotes degradation of β-catenin

https://doi.org/10.18632/oncotarget.10668

Jed J. Kendall, Katherine E. Chaney, Ami V. Patel, Tilat A. Rizvi, David A. Largaespada,  and Nancy Ratner
53191-53203
Abstract  |  PDF  |  HTML  |  Order a Reprint

Beta protein 1 homeoprotein induces cell growth and estrogen-independent tumorigenesis by binding to the estrogen receptor in breast cancer

Beta protein 1 homeoprotein induces cell growth and estrogen-independent tumorigenesis by binding to the estrogen receptor in breast cancer

https://doi.org/10.18632/oncotarget.10633

Sidney W. Fu, Saurabh P. Kirolikar, Erika Ginsburg, Xiaohui Tan, Arnold Schwartz, Samuel J. Simmens, Yan-Gao Man, Joseph J. Pinzone, Christine Teal, Sanket Awate, Barbara K. Vonderhaar,  and Patricia E. Berg
53204-53216
Abstract  |  PDF  |  HTML  |  Order a Reprint

Correlation between overall survival and differential plasma and tissue tumor marker expression in nasopharyngeal carcinoma patients with different sites of organ metastasis

Correlation between overall survival and differential plasma and tissue tumor marker expression in nasopharyngeal carcinoma patients with different sites of organ metastasis

https://doi.org/10.18632/oncotarget.10676

Hung-Ming Wang, Tung-Liang Lin, Yung-Chia Kuo, Hsin-Pai Li, Kai-Ping Chang, Chien-Yu Lin, Hsien-Chi Fan, An-Chi Lin, Chia-Hsun Hsieh, Ngan-Ming Tsang, Li-Yu Lee, Sheng-Chieh Chan, Kar-Wai Lui, Yu-Sun Chang,  and Cheng-Lung Hsu
53217-53229
Abstract  |  PDF  |  HTML  |  Order a Reprint

Transcriptome-wide identification of mRNAs and lincRNAs associated with trastuzumab-resistance in HER2-positive breast cancer

Transcriptome-wide identification of mRNAs and lincRNAs associated with trastuzumab-resistance in HER2-positive breast cancer

https://doi.org/10.18632/oncotarget.10637

Callie R. Merry, Sarah McMahon, Megan E. Forrest, Cynthia F. Bartels, Alina Saiakhova, Courtney A. Bartel, Peter C. Scacheri, Cheryl L. Thompson, Mark W. Jackson, Lyndsay N. Harris,  and Ahmad M. Khalil
53230-53244
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic effect of liver metastasis in lung cancer patients with distant metastasis

Prognostic effect of liver metastasis in lung cancer patients with distant metastasis

https://doi.org/10.18632/oncotarget.10644

Yijiu Ren, Chenyang Dai, Hui Zheng, Fangyu Zhou, Yunlang She, Gening Jiang, Ke Fei, Ping Yang, Dong Xie,  and Chang Chen
53245-53253
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-770-5p inhibits cisplatin chemoresistance in human ovarian cancer by targeting ERCC2

MiR-770-5p inhibits cisplatin chemoresistance in human ovarian cancer by targeting ERCC2

https://doi.org/10.18632/oncotarget.10736

Henan Zhao, Xiaotang Yu, Yanfang Ding, Jinyao Zhao, Guang Wang, Xian Wu, Jiyong Jiang, Chun Peng, Gordon Zhuo Guo,  and Shiying Cui
53254-53268
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The mTOR/AP-1/VEGF signaling pathway regulates vascular endothelial cell growth

The mTOR/AP-1/VEGF signaling pathway regulates vascular endothelial cell growth

https://doi.org/10.18632/oncotarget.10756

Shuo Wang, Jiawei Lu, Qingsheng You, Hua Huang, Yingying Chen,  and Kun Liu
53269-53276
Abstract  |  PDF  |  HTML  |  Order a Reprint

Effect of perineoplasm perinephric adipose tissues on migration of clear cell renal cell carcinoma cells: a potential role of WNT signaling

Effect of perineoplasm perinephric adipose tissues on migration of clear cell renal cell carcinoma cells: a potential role of WNT signaling

https://doi.org/10.18632/oncotarget.10467

Xiaolin Zi, Achim Lusch, Christopher A. Blair, Zhamshid Okhunov, Noriko N. Yokoyama, Shuman Liu, Molly Baker, Victor Huynh,  and Jaime Landman
53277-53288
Abstract  |  PDF  |  HTML  |  Order a Reprint

PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway

PDIA6 promotes the proliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway

https://doi.org/10.18632/oncotarget.10795

Huijun Gao, Bing Sun, Hailu Fu, Xinming Chi, Faming Wang, Xiaoyu Qi, Jun Hu,  and Shujuan Shao
53289-53298
Abstract  |  PDF  |  HTML  |  Order a Reprint

Higher frequency but random distribution of EGFR mutation subtypes in familial lung cancer patients

Higher frequency but random distribution of EGFR mutation subtypes in familial lung cancer patients

https://doi.org/10.18632/oncotarget.10715

Kuo-Hsuan Hsu, Jeng-Sen Tseng, Chih-Liang Wang, Tsung-Ying Yang, Chien-Hua Tseng, Hsuan-Yu Chen, Kun-Chieh Chen, Chi-Ren Tsai, Cheng-Ta Yang, Sung-Liang Yu, Kang-Yi Su, Chong-Jen Yu, Chao-Chi Ho, Te-Chun Hsia, Ming-Fang Wu, Kuo-Liang Chiu, Chien-Ming Liu, Pan-Chyr Yang, Jeremy J.W. Chen,  and Gee-Chen Chang
53299-53308
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CXCL12 promoter methylation and PD-L1 expression as prognostic biomarkers in prostate cancer patients

CXCL12 promoter methylation and PD-L1 expression as prognostic biomarkers in prostate cancer patients

https://doi.org/10.18632/oncotarget.10786

Diane Goltz, Emily Eva Holmes, Heidrun Gevensleben, Verena Sailer, Jörn Dietrich, Maria Jung, Magda Röhler, Sebastian Meller, Jörg Ellinger, Glen Kristiansen,  and Dimo Dietrich
53309-53320
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Volumetric modulated arc therapy for thoracic node metastases: a safe and effective treatment for a neglected disease

Volumetric modulated arc therapy for thoracic node metastases: a safe and effective treatment for a neglected disease

https://doi.org/10.18632/oncotarget.10826

Davide Franceschini, Fiorenza De Rose, Antonella Fogliata, Piera Navarria, Anna Maria Ascolese, Ciro Franzese, Tiziana Comito, Angelo Tozzi, Cristina Iftode, Lucia Di Brina, Giuseppe D'Agostino, Elena Clerici, Luca Cozzi,  and Marta Scorsetti
53321-53329
Abstract  |  PDF  |  HTML  |  Order a Reprint

Tristetraprolin functions in cytoskeletal organization during mouse oocyte maturation

Tristetraprolin functions in cytoskeletal organization during mouse oocyte maturation

https://doi.org/10.18632/oncotarget.10755

Xiaohui Liu, Xiaoyan Li, Rujun Ma, Bo Xiong, Shao-Chen Sun, Honglin Liu,  and Ling Gu
53330-53338
Abstract  |  PDF  |  HTML  |  Order a Reprint

Polo-like kinase 3 and phosphoT273 caspase-8 are associated with improved local tumor control and survival in patients with anal carcinoma treated with concomitant chemoradiotherapy

Polo-like kinase 3 and phosphoT273 caspase-8 are associated with improved local tumor control and survival in patients with anal carcinoma treated with concomitant chemoradiotherapy

https://doi.org/10.18632/oncotarget.10801

Franz Rödel, Daniel Martin, Christina Helmke, Panagiotis Balermpas, Emmanouil Fokas, Ulrike Wieland, Margret Rave-Fränk, Julia Kitz, Yves Matthess, Monika Raab, Klaus Strebhardt,  and Claus Rödel
53339-53349
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IL-17E synergizes with EGF and confers in vitro resistance to EGFR-targeted therapies in TNBC cells

IL-17E synergizes with EGF and confers in vitro resistance to EGFR-targeted therapies in TNBC cells

https://doi.org/10.18632/oncotarget.10804

Yacine Merrouche, Joseph Fabre, Herve Cure, Christian Garbar, Camille Fuselier, Jeremy Bastid, Frank Antonicelli, Reem Al-Daccak, Armand Bensussan,  and Jerome Giustiniani
53350-53361
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association of multiparametric MRI quantitative imaging features with prostate cancer gene expression in MRI-targeted prostate biopsies

Association of multiparametric MRI quantitative imaging features with prostate cancer gene expression in MRI-targeted prostate biopsies

https://doi.org/10.18632/oncotarget.10523

Radka Stoyanova, Alan Pollack, Mandeep Takhar, Charles Lynne, Nestor Parra, Lucia L.C. Lam, Mohammed Alshalalfa, Christine Buerki, Rosa Castillo, Merce Jorda, Hussam Al-deen Ashab, Oleksandr N. Kryvenko, Sanoj Punnen, Dipen J. Parekh, Matthew C. Abramowitz, Robert J. Gillies, Elai Davicioni, Nicholas Erho,  and Adrian Ishkanian
53362-53376
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prexasertib, a Chk1/Chk2 inhibitor, increases the effectiveness of conventional therapy in B-/T- cell progenitor acute lymphoblastic leukemia

Prexasertib, a Chk1/Chk2 inhibitor, increases the effectiveness of conventional therapy in B-/T- cell progenitor acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.10535

Andrea Ghelli Luserna Di Rorà, Ilaria Iacobucci, Enrica Imbrogno, Cristina Papayannidis, Enrico Derenzini, Anna Ferrari, Viviana Guadagnuolo, Valentina Robustelli, Sarah Parisi, Chiara Sartor, Maria Chiara Abbenante, Stefania Paolini,  and Giovanni Martinelli
53377-53391
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The prognostic value of a seven-microRNA classifier as a novel biomarker for the prediction and detection of recurrence in glioma patients

The prognostic value of a seven-microRNA classifier as a novel biomarker for the prediction and detection of recurrence in glioma patients

https://doi.org/10.18632/oncotarget.10534

Wanghao Chen, Qiang Yu, Bo Chen, Xingyu Lu,  and Qiaoyu Li
53392-53413
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Native and engineered tropism of vectors derived from a rare species D adenovirus serotype 43

Native and engineered tropism of vectors derived from a rare species D adenovirus serotype 43

https://doi.org/10.18632/oncotarget.10800

Natalya Belousova, Galina Mikheeva, Chiyi Xiong, Loren J. Stagg, Mihai Gagea, Patricia S. Fox, Roland L. Bassett, John E. Ladbury, Michael B. Braun, Thilo Stehle, Chun Li,  and Victor Krasnykh
53414-53429
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Radiation driven epithelial-mesenchymal transition is mediated by Notch signaling in breast cancer

Radiation driven epithelial-mesenchymal transition is mediated by Notch signaling in breast cancer

https://doi.org/10.18632/oncotarget.10802

Rae-Kwon Kim, Neha Kaushik, Yongjoon Suh, Ki-Chun Yoo, Yan-Hong Cui, Min-Jung Kim, Hae-June Lee, In-Gyu Kim,  and Su-Jae Lee
53430-53442
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MACC1 is post-transcriptionally regulated by miR-218 in colorectal cancer

MACC1 is post-transcriptionally regulated by miR-218 in colorectal cancer

https://doi.org/10.18632/oncotarget.10803

Katharina Ilm, Steffen Fuchs, Giridhar Mudduluru,  and Ulrike Stein
53443-53458
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gelsolin suppresses gastric cancer metastasis through inhibition of PKR-p38 signaling

Gelsolin suppresses gastric cancer metastasis through inhibition of PKR-p38 signaling

https://doi.org/10.18632/oncotarget.10557

Xiangliang Yuan, Weiwei Wang, Junhua Li, Peiming Zheng, Ping Dong, Lei Chen, Yunlan Zhou, Guohua Xie, Dakang Xu, Yingbin Liu,  and Lisong Shen
53459-53470
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Crosstalk among the proteome, lysine phosphorylation, and acetylation in romidepsin-treated colon cancer cells

Crosstalk among the proteome, lysine phosphorylation, and acetylation in romidepsin-treated colon cancer cells

https://doi.org/10.18632/oncotarget.10840

Tian-Yun Wang, Yu-Rong Chai, Yan-Long Jia, Jian-Hui Gao, Xiao-Jun Peng,  and Hua-Feng Han
53471-53501
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety

Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety

https://doi.org/10.18632/oncotarget.10609

Aixian Lan, Wenjun Li, Yao Liu, Zhaohui Xiong, Xinyan Zhang, Shanshan Zhou, Olesya Palko, Hao Chen, Mayanga Kapita, Justin R. Prigge, Edward E. Schmidt, Xin Chen, Zheng Sun,  and Xiaoxin Luke Chen
53502-53514
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Simultaneous inhibition of Vps34 kinase would enhance PI3Kδ inhibitor cytotoxicity in the B-cell malignancies

Simultaneous inhibition of Vps34 kinase would enhance PI3Kδ inhibitor cytotoxicity in the B-cell malignancies

https://doi.org/10.18632/oncotarget.10650

Xiaochuan Liu, Aoli Wang, Xiaofei Liang, Juanjuan Liu, Fengming Zou, Cheng Chen, Zheng Zhao, Yuanxin Deng, Hong Wu, Ziping Qi, Beilei Wang, Li Wang, Feiyang Liu, Yunhe Xu, Wenchao Wang, Stacey M. Fernandes, Richard M. Stone, Ilene A. Galinsky, Jennifer R. Brown, Teckpeng Loh, James D. Griffin, Shanchun Zhang, Ellen L. Weisberg, Xin Zhang, Jing Liu,  and Qingsong Liu
53515-53525
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oncogenic Ras triggers hyperproliferation and impairs polarized colonic morphogenesis by autocrine ErbB3 signaling

Oncogenic Ras triggers hyperproliferation and impairs polarized colonic morphogenesis by autocrine ErbB3 signaling

https://doi.org/10.18632/oncotarget.10658

Yvonne Möller, Markus Morkel, Jens Schmid, Sven Beyes, Janina Hendrick, Michaela Strotbek, Pamela Riemer, Simone Schmid, Lisa C. Schmitt, Roland Kontermann, Thomas Mürdter, Matthias Schwab, Christine Sers,  and Monilola A. Olayioye
53526-53539
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hypoxia inducible factor-1α regulates a pro-invasive phenotype in acute monocytic leukemia

Hypoxia inducible factor-1α regulates a pro-invasive phenotype in acute monocytic leukemia

https://doi.org/10.18632/oncotarget.10660

Jessica Migliavacca, Stefano Percio, Roberta Valsecchi, Elisabetta Ferrero, Antonello Spinelli, Maurilio Ponzoni, Cristina Tresoldi, Linda Pattini, Rosa Bernardi,  and Nadia Coltella
53540-53557
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-7 reverses the resistance to BRAFi in melanoma by targeting EGFR/IGF-1R/CRAF and inhibiting the MAPK and PI3K/AKT signaling pathways

miR-7 reverses the resistance to BRAFi in melanoma by targeting EGFR/IGF-1R/CRAF and inhibiting the MAPK and PI3K/AKT signaling pathways

https://doi.org/10.18632/oncotarget.10669

Xiaoyan Sun, Jun Li, Yanhong Sun, Yi Zhang, Liyun Dong, Chen Shen, Liu Yang, Ming Yang, Yan Li, Guanxin Shen, Yating Tu,  and Juan Tao
53558-53570
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Treatment with an SLC12A1 antagonist inhibits tumorigenesis in a subset of hepatocellular carcinomas

Treatment with an SLC12A1 antagonist inhibits tumorigenesis in a subset of hepatocellular carcinomas

https://doi.org/10.18632/oncotarget.10670

Fei Teng, Meng Guo, Fang Liu, Ce Wang, Jiayong Dong, Lei Zhang, You Zou, Rui Chen, Keyan Sun, Hong Fu, Zhiren Fu, Wenyuan Guo,  and Guoshan Ding
53571-53582
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The mutational profile and infiltration pattern of murine MLH1-/- tumors: concurrences, disparities and cell line establishment for functional analysis

The mutational profile and infiltration pattern of murine MLH1-/- tumors: concurrences, disparities and cell line establishment for functional analysis

https://doi.org/10.18632/oncotarget.10677

Claudia Maletzki, Franziska Beyrich, Maja Hühns, Ernst Klar,  and Michael Linnebacher
53583-53598
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ZKSCAN3 promotes bladder cancer cell proliferation, migration, and invasion

ZKSCAN3 promotes bladder cancer cell proliferation, migration, and invasion

https://doi.org/10.18632/oncotarget.10679

Takashi Kawahara, Satoshi Inoue, Hiroki Ide, Eiji Kashiwagi, Shinji Ohtake, Taichi Mizushima, Peng Li, Yi Li, Yichun Zheng, Hiroji Uemura, George J. Netto, Hitoshi Ishiguro,  and Hiroshi Miyamoto
53599-53610
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Aberrant transcriptional networks in step-wise neurogenesis of paroxysmal kinesigenic dyskinesia-induced pluripotent stem cells

Aberrant transcriptional networks in step-wise neurogenesis of paroxysmal kinesigenic dyskinesia-induced pluripotent stem cells

https://doi.org/10.18632/oncotarget.10680

Chun Li, Yu Ma, Kunshan Zhang, Junjie Gu, Fan Tang, Shengdi Chen, Li Cao, Siguang Li,  and Ying Jin
53611-53627
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression of glutamine metabolism-related proteins in thyroid cancer

Expression of glutamine metabolism-related proteins in thyroid cancer

https://doi.org/10.18632/oncotarget.10682

Hye Min Kim, Yu Kyung Lee,  and Ja Seung Koo
53628-53641
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

AMP-activated protein kinase is involved in the activation of the Fanconi anemia/BRCA pathway in response to DNA interstrand crosslinks

AMP-activated protein kinase is involved in the activation of the Fanconi anemia/BRCA pathway in response to DNA interstrand crosslinks

https://doi.org/10.18632/oncotarget.10686

Min Jeong Chun, Sunshin Kim, Soo Kyung Hwang, Bong Sub Kim, Hyoun Geun Kim, Hae In Choi, Jong Heon Kim, Sung Ho Goh,  and Chang-Hun Lee
53642-53653
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

AMPKα1 deletion in fibroblasts promotes tumorigenesis in athymic nude mice by p52-mediated elevation of erythropoietin and CDK2

AMPKα1 deletion in fibroblasts promotes tumorigenesis in athymic nude mice by p52-mediated elevation of erythropoietin and CDK2

https://doi.org/10.18632/oncotarget.10687

Yanhong Zhou, Hairong Xu, Ye Ding, Qiulun Lu, Ming-Hui Zou,  and Ping Song
53654-53667
Abstract  |  PDF  |  HTML  |  Order a Reprint

Impact of sex, age, and ethnicity/race on the survival of patients with rectal cancer in the United States from 1988 to 2012

Impact of sex, age, and ethnicity/race on the survival of patients with rectal cancer in the United States from 1988 to 2012

https://doi.org/10.18632/oncotarget.10696

Martin D. Berger, Dongyun Yang, Yu Sunakawa, Wu Zhang, Yan Ning, Satoshi Matsusaka, Satoshi Okazaki, Yuji Miyamoto, Mitsukuni Suenaga, Marta Schirripa, Annika Medea Lenz, Pierre Bohanes, Afsaneh Barzi, Jane C. Figueiredo, Diana L. Hanna,  and Heinz-Josef Lenz
53668-53678
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting of heme oxygenase-1 attenuates the negative impact of Ikaros isoform 6 in adult BCR-ABL1-positive B-ALL

Targeting of heme oxygenase-1 attenuates the negative impact of Ikaros isoform 6 in adult BCR-ABL1-positive B-ALL

https://doi.org/10.18632/oncotarget.10725

Xiaojing Lin, Xingli Zou, Ziming Wang, Qin Fang, Shuya Chen, Jun Huang, Nana Zhe, Meisheng Yu, Yaming Zhang,  and Jishi Wang
53679-53701
Abstract  |  PDF  |  HTML  |  Order a Reprint

Decreased Dp71 expression is associated with gastric adenocarcinoma prognosis

Decreased Dp71 expression is associated with gastric adenocarcinoma prognosis

https://doi.org/10.18632/oncotarget.10724

Sipin Tan, Jin Tan, Sichuang Tan, Shuai Zhao, Xiaoxia Cao, Zhikang Chen, Qiaocheng Weng, Huali Zhang, Kangkai Wang, Jiang Zhou,  and Xianzhong Xiao
53702-53711
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The mitotic tensegrity guardian tau protects mammary epithelia from katanin-like1-induced aneuploidy

The mitotic tensegrity guardian tau protects mammary epithelia from katanin-like1-induced aneuploidy

https://doi.org/10.18632/oncotarget.10728

Haruka Sudo,  and Kazunori Nakajima
53712-53734
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-28 modulates exhaustive differentiation of T cells through silencing programmed cell death-1 and regulating cytokine secretion

miR-28 modulates exhaustive differentiation of T cells through silencing programmed cell death-1 and regulating cytokine secretion

https://doi.org/10.18632/oncotarget.10731

Qing Li, Nathan Johnston, Xiufen Zheng, Hongmei Wang, Xusheng Zhang, Dian Gao,  and Weiping Min
53735-53750
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oral administration of withaferin A inhibits carcinogenesis of prostate in TRAMP model

Oral administration of withaferin A inhibits carcinogenesis of prostate in TRAMP model

https://doi.org/10.18632/oncotarget.10733

Suman Suman, Trinath P. Das, Jim Moselhy, Deeksha Pal, Venkatesh Kolluru, Houda Alatassi, Murali K. Ankem,  and Chendil Damodaran
53751-53761
Abstract  |  PDF  |  HTML  |  Order a Reprint

An assessment of factors associated with quality of randomized controlled trials for smoking cessation

An assessment of factors associated with quality of randomized controlled trials for smoking cessation

https://doi.org/10.18632/oncotarget.10742

Hong Fan, Fujian Song, Hai Gu, Jianming Wang, Guizhen Jia, Moyuan Lu, Jiao Qian, Lei Wang, Jiemiao Shen,  and Zhewen Ren
53762-53771
Abstract  |  PDF  |  HTML  |  Order a Reprint

Comparative transcriptome analysis reveals a regulatory network of microRNA-29b during mouse early embryonic development

Comparative transcriptome analysis reveals a regulatory network of microRNA-29b during mouse early embryonic development

https://doi.org/10.18632/oncotarget.10741

Ying Wang, Tao Zhou, Jinyuan Wan, Ye Yang, Xiaojiao Chen, Jiayi Wang, Cheng Zhou, Mingxi Liu, Xiufeng Ling,  and Junqiang Zhang
53772-53782
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A pancreatic ductal adenocarcinoma subpopulation is sensitive to FK866, an inhibitor of NAMPT

A pancreatic ductal adenocarcinoma subpopulation is sensitive to FK866, an inhibitor of NAMPT

https://doi.org/10.18632/oncotarget.10776

Marine Barraud, Jonathan Garnier, Celine Loncle, Odile Gayet, Charlotte Lequeue, Sophie Vasseur, Benjamin Bian, Pauline Duconseil, Marine Gilabert, Martin Bigonnet, Aurélie Maignan, Vincent Moutardier, Stephane Garcia, Olivier Turrini, Jean-Robert Delpero, Marc Giovannini, Philippe Grandval, Mohamed Gasmi, Mehdi Ouaissi, Veronique Secq, Flora Poizat, Nicolas Guibert, Juan Iovanna,  and Nelson Dusetti
53783-53796
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Immunomodulation by memantine in therapy of Alzheimer's disease is mediated through inhibition of Kv1.3 channels and T cell responsiveness

Immunomodulation by memantine in therapy of Alzheimer's disease is mediated through inhibition of Kv1.3 channels and T cell responsiveness

https://doi.org/10.18632/oncotarget.10777

Theresa Lowinus, Tanima Bose, Stefan Busse, Mandy Busse, Dirk Reinhold, Burkhart Schraven,  and Ursula H.H. Bommhardt
53797-53807
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-155 is a potential molecular marker of natural killer/T-cell lymphoma

MicroRNA-155 is a potential molecular marker of natural killer/T-cell lymphoma

https://doi.org/10.18632/oncotarget.10780

Xudong Zhang, Weiguo Ji, Ruixia Huang, Lifeng Li, Xinhua Wang, Ling Li, Xiaorui Fu, Zhenchang Sun, Zhaoming Li, Qingjiang Chen,  and Mingzhi Zhang
53808-53819
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circulating microRNA profiles in plasma: identification of miR-224 as a novel diagnostic biomarker in hepatocellular carcinoma independent of hepatic function

Circulating microRNA profiles in plasma: identification of miR-224 as a novel diagnostic biomarker in hepatocellular carcinoma independent of hepatic function

https://doi.org/10.18632/oncotarget.10781

Wataru Okajima, Shuhei Komatsu, Daisuke Ichikawa, Mahito Miyamae, Tsutomu Kawaguchi, Shoji Hirajima, Takuma Ohashi, Taisuke Imamura, Jun Kiuchi, Tomohiro Arita, Hirotaka Konishi, Atsushi Shiozaki, Ryo Moriumura, Hisashi Ikoma, Kazuma Okamoto, Hiroki Taniguchi, Yoshito Itoh,  and Eigo Otsuji
53820-53836
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PDHA1 gene knockout in prostate cancer cells results in metabolic reprogramming towards greater glutamine dependence

PDHA1 gene knockout in prostate cancer cells results in metabolic reprogramming towards greater glutamine dependence

https://doi.org/10.18632/oncotarget.10782

Yaqing Li, Xiaoran Li, Xiaoli Li, Yali Zhong, Yasai Ji, Dandan Yu, Mingzhi Zhang, Jian-Guo Wen, Hongquan Zhang, Mariusz Adam Goscinski, Jahn M. Nesland,  and Zhenhe Suo
53837-53852
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reduced miR-550a-3p leads to breast cancer initiation, growth, and metastasis by increasing levels of ERK1 and 2

Reduced miR-550a-3p leads to breast cancer initiation, growth, and metastasis by increasing levels of ERK1 and 2

https://doi.org/10.18632/oncotarget.10793

Jar-Yi Ho, Ren-Jun Hsu, Chih-Hsi Wu, Guo-Shiou Liao, Hong-Wei Gao, Tong-Hong Wang,  and Cheng-Ping Yu
53853-53868
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

c-CBL regulates melanoma proliferation, migration, invasion and the FAK-SRC-GRB2 nexus

c-CBL regulates melanoma proliferation, migration, invasion and the FAK-SRC-GRB2 nexus

https://doi.org/10.18632/oncotarget.10861

Minakshi Nihal,  and Gary S. Wood
53869-53880
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma

Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma

https://doi.org/10.18632/oncotarget.10692

Eric W. Prince, Ilango Balakrishnan, Monil Shah, Jean M. Mulcahy Levy, Andrea M. Griesinger, Irina Alimova, Peter S. Harris, Diane K. Birks, Andrew M. Donson, Nathan Davidson, Marc Remke, Michael D. Taylor, Michael H. Handler, Nicholas K. Foreman, Sujatha Venkataraman,  and Rajeev Vibhakar
53881-53894
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Elevated expression of RNA methyltransferase BCDIN3D predicts poor prognosis in breast cancer

Elevated expression of RNA methyltransferase BCDIN3D predicts poor prognosis in breast cancer

https://doi.org/10.18632/oncotarget.9656

Ling Yao, Yayun Chi, Xin Hu, Shan Li, Feng Qiao, Jong Wu,  and Zhi-Ming Shao
53895-53902
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Characteristics of human papillomaviruses infection in men with genital warts in Shanghai

Characteristics of human papillomaviruses infection in men with genital warts in Shanghai

https://doi.org/10.18632/oncotarget.9708

Xiaogang Chen, Liang Li, Yongxian Lai, Qinxiu Liu, Jianna Yan,  and Yichen Tang
53903-53910
Abstract  |  PDF  |  HTML  |  Order a Reprint

Percutaneous intraductal radiofrequency ablation in the management of unresectable Bismuth types III and IV hilar cholangiocarcinoma

Percutaneous intraductal radiofrequency ablation in the management of unresectable Bismuth types III and IV hilar cholangiocarcinoma

https://doi.org/10.18632/oncotarget.10116

Yu Wang, Wei Cui, Wenzhe Fan, Yingqiang Zhang, Wang Yao, Kunbo Huang,  and Jiaping Li
53911-53920
Abstract  |  PDF  |  HTML  |  Order a Reprint

High dose and compartmental target volume may improve patient outcome after radiotherapy for pelvic bone metastases from hepatocellular carcinoma

High dose and compartmental target volume may improve patient outcome after radiotherapy for pelvic bone metastases from hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9767

Taehyung Kim, Hye Jung Cha, Jun Won Kim, Jinsil Seong,  and Ik Jae Lee
53921-53929
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Virus infection facilitates the development of severe pneumonia in transplant patients with hematologic malignancies

Virus infection facilitates the development of severe pneumonia in transplant patients with hematologic malignancies

https://doi.org/10.18632/oncotarget.10182

Caifeng Yue, ZhiJie Kang, Kexin Ai, Duorong Xu, Jim Wu, Yujia Pan, JinSong Yan, Min Liu,  and Quentin Liu
53930-53940
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

The protective effect of longer duration of breastfeeding against pregnancy-associated triple negative breast cancer

The protective effect of longer duration of breastfeeding against pregnancy-associated triple negative breast cancer

https://doi.org/10.18632/oncotarget.9690

Wael M. ElShamy
53941-53950
Abstract  |  PDF  |  HTML  |  Order a Reprint

Interplay between chronic kidney disease (CKD) and upper tract urothelial carcinomas (UUC): foe or friend?

Interplay between chronic kidney disease (CKD) and upper tract urothelial carcinomas (UUC): foe or friend?

https://doi.org/10.18632/oncotarget.9753

Yehong Han, Dawei Shou, Liang Wen, Jianguang Shi, Jian Ding, Ping Gong,  and Weihua Gong
53951-53958
Abstract  |  PDF  |  HTML  |  Order a Reprint

Important molecular genetic markers of colorectal cancer

Important molecular genetic markers of colorectal cancer

https://doi.org/10.18632/oncotarget.9796

Anna V. Kudryavtseva, Anastasia V. Lipatova, Andrew R. Zaretsky, Alexey A. Moskalev, Maria S. Fedorova, Anastasiya S. Rasskazova, Galina A. Shibukhova, Anastasiya V. Snezhkina, Andrey D. Kaprin, Boris Y. Alekseev, Alexey A. Dmitriev,  and George S. Krasnov
53959-53983
Abstract  |  PDF  |  HTML  |  Order a Reprint

Emerging roles and underlying molecular mechanisms of DNAJB6 in cancer

Emerging roles and underlying molecular mechanisms of DNAJB6 in cancer

https://doi.org/10.18632/oncotarget.9803

Erhong Meng, Lalita A. Shevde,  and Rajeev S. Samant
53984-53996
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeting BET bromodomain proteins in solid tumors

Targeting BET bromodomain proteins in solid tumors

https://doi.org/10.18632/oncotarget.9804

Vaibhav Sahai, Amanda J. Redig, Katharine A. Collier, Frank D. Eckerdt,  and Hidayatullah G. Munshi
53997-54009
Abstract  |  PDF  |  HTML  |  Order a Reprint

New insights into the unfolded protein response in stem cells

New insights into the unfolded protein response in stem cells

https://doi.org/10.18632/oncotarget.9833

Yanzhou Yang, Hoi Hung Cheung, JiaJie Tu, Kai Kei Miu,  and Wai Yee Chan
54010-54027
Abstract  |  PDF  |  HTML  |  Order a Reprint

DMETTM (Drug Metabolism Enzymes and Transporters): a pharmacogenomic platform for precision medicine

DMETTM (Drug Metabolism Enzymes and Transporters): a pharmacogenomic platform for precision medicine

https://doi.org/10.18632/oncotarget.9927

Mariamena Arbitrio, Maria Teresa Di Martino, Francesca Scionti, Giuseppe Agapito, Pietro Hiram Guzzi, Mario Cannataro, Pierfrancesco Tassone,  and Pierosandro Tagliaferri
54028-54050
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prostate cancer and the unfolded protein response

Prostate cancer and the unfolded protein response

https://doi.org/10.18632/oncotarget.9912

Margrethe Storm, Xia Sheng, Yke Jildouw Arnoldussen,  and Fahri Saatcioglu
54051-54066
Abstract  |  PDF  |  HTML  |  Order a Reprint

N-acetylgalactosaminyltransferases in cancer

N-acetylgalactosaminyltransferases in cancer

https://doi.org/10.18632/oncotarget.10042

Muhammad Ramzan Manwar Hussain, Daniel C. Hoessli,  and Min Fang
54067-54081
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cancer subtypes classification using long non-coding RNA

Cancer subtypes classification using long non-coding RNA

https://doi.org/10.18632/oncotarget.10213

Ronan Flippot, Gabriel G. Malouf, Xiaoping Su, Roger Mouawad, Jean-Philippe Spano,  and David Khayat
54082-54093
Abstract  |  PDF  |  HTML  |  Order a Reprint


Copyright © 2017 Impact Journals
Impact Journals is a registered trademark of Impact Journals, LLC