Oncotarget

Vol 7, No 32

August 9, 2016

View Archive »

Order a Reprint

About The Cover

Copy number and heterozygosity of SOX9 mutants. See Javier et al.

Table of Contents

Editorial

NADPH: new oxygen for the ROS theory of aging

NADPH: new oxygen for the ROS theory of aging

https://doi.org/10.18632/oncotarget.10744

Pablo J. Fernandez-Marcos,  and Sandrina Nóbrega-Pereira
50814-50815
PDF  |  Order a Reprint

Targeting LIM kinases in taxane resistant tumors

Targeting LIM kinases in taxane resistant tumors

https://doi.org/10.18632/oncotarget.10816

Chloé Prunier, Reuben Kapur,  and Laurence Lafanechère
50816-50817
PDF  |  Order a Reprint

Editorial: Autophagy and Cell Death

Autophagy complexes cell death by necroptosis

Autophagy complexes cell death by necroptosis

https://doi.org/10.18632/oncotarget.10640

Megan L. Goodall, Scott D. Cramer,  and Andrew Thorburn
50818-50819
PDF  |  Order a Reprint

Novel functions of Fanconi anemia proteins in selective autophagy and inflammation

Novel functions of Fanconi anemia proteins in selective autophagy and inflammation

https://doi.org/10.18632/oncotarget.10970

Rhea Sumpter,  and Beth Levine
50820-50821
PDF  |  Order a Reprint

Research Perspectives

PGRMC1 regulation by phosphorylation: potential new insights in controlling biological activity

PGRMC1 regulation by phosphorylation: potential new insights in controlling biological activity

https://doi.org/10.18632/oncotarget.10691

Michael A. Cahill, Jalal A. Jazayeri, Zaklina Kovacevic,  and Des R. Richardson
50822-50827
Abstract  |  PDF  |  HTML  |  Order a Reprint

Research Papers: Gerotarget (Focus on Aging)

Virtual screening, optimization, and identification of a novel specific PTP-MEG2 Inhibitor with potential therapy for T2DM

Virtual screening, optimization, and identification of a novel specific PTP-MEG2 Inhibitor with potential therapy for T2DM

https://doi.org/10.18632/oncotarget.10341

Meiyan Wang, Xiaobo Li, Lei Dong, Xiubo Chen, Weiren Xu,  and Runling Wang
50828-50834
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Leukocyte telomere length and mortality risk in patients with type 2 diabetes

Leukocyte telomere length and mortality risk in patients with type 2 diabetes

https://doi.org/10.18632/oncotarget.10615

Anna Rita Bonfigli, Liana Spazzafumo, Francesco Prattichizzo, Massimiliano Bonafè, Emanuela Mensà, Luigina Micolucci, Angelica Giuliani, Paolo Fabbietti, Roberto Testa, Massimo Boemi, Fabrizia Lattanzio,  and Fabiola Olivieri
50835-50844
Abstract  |  PDF  |  HTML  |  Order a Reprint

Six plant extracts delay yeast chronological aging through different signaling pathways

Six plant extracts delay yeast chronological aging through different signaling pathways

https://doi.org/10.18632/oncotarget.10689

Vicky Lutchman, Pamela Dakik, Mélissa McAuley, Berly Cortes, George Ferraye, Leonid Gontmacher, David Graziano, Fatima-Zohra Moukhariq, Éric Simard,  and Vladimir I. Titorenko
50845-50863
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activation of proinflammatory signaling by 4-hydroxynonenal-Src adducts in aged kidneys

Activation of proinflammatory signaling by 4-hydroxynonenal-Src adducts in aged kidneys

https://doi.org/10.18632/oncotarget.10854

Eun Ji Jang, Dae Hyun Kim, Bonggi Lee, Eun Kyeong Lee, Ki Wung Chung, Kyoung Mi Moon, Min Jo Kim, Hye Jin An, Ji Won Jeong, Ye Ra Kim, Byung Pal Yu,  and Hae Young Chung
50864-50874
Abstract  |  PDF  |  HTML  |  Order a Reprint

Research Papers: Pathology

Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma

Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma

https://doi.org/10.18632/oncotarget.9682

Breanna M. Javier, Rona Yaeger, Lu Wang, Francisco Sanchez-Vega, Ahmet Zehir, Sumit Middha, Justyna Sadowska, Efsevia Vakiani, Jinru Shia, David Klimstra, Marc Ladanyi, Christine A. Iacobuzio-Donahue,  and Jaclyn F. Hechtman
50875-50882
Abstract  |  PDF  |  HTML  |  Interview with Dr. Jaclyn Hechtman  |  Order a Reprint

Phosphorylation of kinase insert domain receptor by cyclin-dependent kinase 5 at serine 229 is associated with invasive behavior and poor prognosis in prolactin pituitary adenomas

Phosphorylation of kinase insert domain receptor by cyclin-dependent kinase 5 at serine 229 is associated with invasive behavior and poor prognosis in prolactin pituitary adenomas

https://doi.org/10.18632/oncotarget.10550

Weiyan Xie, Chunhui Liu, Dan Wu, Zhenye Li, Chuzhong Li,  and Yazhuo Zhang
50883-50894
Abstract  |  PDF  |  HTML  |  Order a Reprint

Viscoelasticity as a measurement of clot structure in poorly controlled type 2 diabetes patients: towards a precision and personalized medicine approach

Viscoelasticity as a measurement of clot structure in poorly controlled type 2 diabetes patients: towards a precision and personalized medicine approach

https://doi.org/10.18632/oncotarget.10618

Etheresia Pretorius,  and Janette Bester
50895-50907
Abstract  |  PDF  |  HTML  |  Order a Reprint

ABO blood type is associated with ovarian reserve in Chinese women with subfertility

ABO blood type is associated with ovarian reserve in Chinese women with subfertility

https://doi.org/10.18632/oncotarget.10766

Liangshan Mu, Wumin Jin, Haiyan Yang, Xia Chen, Jiexue Pan, Jia Lin, Peiyu Wang,  and Xuefeng Huang
50908-50913
Abstract  |  PDF  |  HTML  |  Order a Reprint

Partial loss of interleukin 2 receptor gamma function in pigs provides mechanistic insights for the study of human immunodeficiency syndrome

Partial loss of interleukin 2 receptor gamma function in pigs provides mechanistic insights for the study of human immunodeficiency syndrome

https://doi.org/10.18632/oncotarget.10812

Yun-Jung Choi, Kiho Lee, Woo-Jin Park, Deug-Nam Kwon, Chankyu Park, Jeong Tae Do, Hyuk Song, Seong-Keun Cho, Kwang-Wook Park, Alana N. Brown, Melissa S. Samuel, Clifton N. Murphy, Randall S. Prather,  and Jin-Hoi Kim
50914-50926
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epsin2 promotes polarity establishment and meiotic division through activating Cdc42 in mouse oocyte

Epsin2 promotes polarity establishment and meiotic division through activating Cdc42 in mouse oocyte

https://doi.org/10.18632/oncotarget.10815

Ling Li, Longsen Han, Jiaqi Zhang, Xiaohui Liu, Rujun Ma, Xiaojing Hou, Juan Ge,  and Qiang Wang
50927-50936
Abstract  |  PDF  |  HTML  |  Order a Reprint

TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells

TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells

https://doi.org/10.18632/oncotarget.10853

Yuan Wang, Yan Wang,  and Gui-Rong Li
50937-50951
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers: Immunology

Activation of intrahepatic CD4+CXCR5+ T and CD19+ B cells is associated with viral clearance in a mouse model of acute hepatitis B virus infection

Activation of intrahepatic CD4+CXCR5+ T and CD19+ B cells is associated with viral clearance in a mouse model of acute hepatitis B virus infection

https://doi.org/10.18632/oncotarget.10688

Xiao-Fei Song, Ting-Ting Hu, Yu Lei, Hu Li, Li Zhang, Miao Zhang, Bin Liu, Min Chen, Huai-Dong Hu, Hong Ren,  and Peng Hu
50952-50962
Abstract  |  PDF  |  HTML  |  Order a Reprint

Research Papers

Elevated neutrophil-to-lymphocyte ratio is an independent poor prognostic factor in patients with intrahepatic cholangiocarcinoma

Elevated neutrophil-to-lymphocyte ratio is an independent poor prognostic factor in patients with intrahepatic cholangiocarcinoma

https://doi.org/10.18632/oncotarget.7680

Guohe Lin, Yongcheng Liu, Shuhong Li, Yize Mao, Jun Wang, Zeyu Shuang, Jianlin Chen,  and Shengping Li
50963-50971
Abstract  |  PDF  |  HTML  |  Order a Reprint

Interaction between the human papillomavirus 16 E7 oncoprotein and gelsolin ignites cancer cell motility and invasiveness

Interaction between the human papillomavirus 16 E7 oncoprotein and gelsolin ignites cancer cell motility and invasiveness

https://doi.org/10.18632/oncotarget.8646

Paola Matarrese, Claudia Abbruzzese, Anna Maria Mileo, Rosa Vona, Barbara Ascione, Paolo Visca, Francesca Rollo, Maria Benevolo, Walter Malorni,  and Marco G. Paggi
50972-50985
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A pilot study using dynamic contrast enhanced-MRI as a response biomarker of the radioprotective effect of memantine in patients receiving whole brain radiotherapy

A pilot study using dynamic contrast enhanced-MRI as a response biomarker of the radioprotective effect of memantine in patients receiving whole brain radiotherapy

https://doi.org/10.18632/oncotarget.9653

Philip Wong, Ilana R. Leppert, David Roberge, Karim Boudam, Paul D. Brown, Thierry Muanza, G. Bruce Pike, Jeffrey Chankowsky,  and Catalin Mihalcioiu
50986-50996
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SSX2 regulates focal adhesion but does not drive the epithelial to mesenchymal transition in prostate cancer

SSX2 regulates focal adhesion but does not drive the epithelial to mesenchymal transition in prostate cancer

https://doi.org/10.18632/oncotarget.9802

Jordan E. Bloom,  and Douglas G. McNeel
50997-51011
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HER2-HER3 dimer quantification by FLIM-FRET predicts breast cancer metastatic relapse independently of HER2 IHC status

HER2-HER3 dimer quantification by FLIM-FRET predicts breast cancer metastatic relapse independently of HER2 IHC status

https://doi.org/10.18632/oncotarget.9963

Gregory Weitsman, Paul R. Barber, Lan K. Nguyen, Katherine Lawler, Gargi Patel, Natalie Woodman, Muireann T. Kelleher, Sarah E. Pinder, Mark Rowley, Paul A. Ellis, Anand D. Purushotham, Anthonius C. Coolen, Boris N. Kholodenko, Borivoj Vojnovic, Cheryl Gillett,  and Tony Ng
51012-51026
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impact of the SCF signaling pathway on leukemia stem cell-mediated ATL initiation and progression in an HBZ transgenic mouse model

Impact of the SCF signaling pathway on leukemia stem cell-mediated ATL initiation and progression in an HBZ transgenic mouse model

https://doi.org/10.18632/oncotarget.10210

Wakako Kuribayashi, Kazuya Takizawa, Kenji Sugata, Madoka Kuramitsu, Haruka Momose, Eita Sasaki, Yuki Hiradate, Keiko Furuhata, Yoshihisa Asada, Atsushi Iwama, Masao Matsuoka, Takuo Mizukami,  and Isao Hamaguchi
51027-51043
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The eIF2α serine 51 phosphorylation-ATF4 arm promotes HIPPO signaling and cell death under oxidative stress

The eIF2α serine 51 phosphorylation-ATF4 arm promotes HIPPO signaling and cell death under oxidative stress

https://doi.org/10.18632/oncotarget.10480

Kamindla Rajesh, Jothilatha Krishnamoorthy, Jyotsana Gupta, Urszula Kazimierczak, Andreas I. Papadakis, Zhilin Deng, Shuo Wang, Shinji Kuninaka,  and Antonis E. Koromilas
51044-51058
Abstract  |  PDF  |  HTML  |  Order a Reprint

Nomograms predicting long-term overall survival and cancer-specific survival in head and neck squamous cell carcinoma patients

Nomograms predicting long-term overall survival and cancer-specific survival in head and neck squamous cell carcinoma patients

https://doi.org/10.18632/oncotarget.10595

Jun Ju, Jia Wang, Chao Ma, Yun Li, Zhenyan Zhao, Tao Gao, Qianwei Ni,  and Moyi Sun
51059-51068
Abstract  |  PDF  |  HTML  |  Order a Reprint

Superiority of lymph node ratio-based staging system for prognostic prediction in 2575 patients with gastric cancer: validation analysis in a large single center

Superiority of lymph node ratio-based staging system for prognostic prediction in 2575 patients with gastric cancer: validation analysis in a large single center

https://doi.org/10.18632/oncotarget.9714

Lin-Yong Zhao, Chang-Chun Li, Lu-Yu Jia, Xiao-Long Chen, Wei-Han Zhang, Xin-Zu Chen, Kun Yang, Kai Liu, Yi-Gao Wang, Lian Xue, Bo Zhang, Zhi-Xin Chen, Jia-Ping Chen, Zong-Guang Zhou,  and Jian-Kun Hu
51069-51081
Abstract  |  PDF  |  HTML  |  Order a Reprint

The anti-apoptotic PON2 protein is Wnt/β-catenin-regulated and correlates with radiotherapy resistance in OSCC patients

The anti-apoptotic PON2 protein is Wnt/β-catenin-regulated and correlates with radiotherapy resistance in OSCC patients

https://doi.org/10.18632/oncotarget.9013

Maximilian Krüger, Julianna Amort, Petra Wilgenbus, Johanna P. Helmstädter, Irina Grechowa, Julia Ebert, Stefan Tenzer, Maximilian Moergel, Ines Witte,  and Sven Horke
51082-51095
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth

The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth

https://doi.org/10.18632/oncotarget.9315

Harini Nivarthi, Claire Gordziel, Madeleine Themanns, Nina Kramer, Markus Eberl, Björn Rabe, Michaela Schlederer, Stefan Rose-John, Thomas Knösel, Lukas Kenner, Patricia Freund, Fritz Aberger, Xiaonan Han, Robert Kralovics, Helmut Dolznig, Susanne Jennek, Karlheinz Friedrich,  and Richard Moriggl
51096-51106
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel CBL-Bflox/flox mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells

A novel CBL-Bflox/flox mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells

https://doi.org/10.18632/oncotarget.9812

Benjamin Goetz, Wei An, Bhopal Mohapatra, Neha Zutshi, Fany Iseka, Matthew D. Storck, Jane Meza, Yuri Sheinin, Vimla Band,  and Hamid Band
51107-51123
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dynamic fluorescent imaging with the activatable probe, γ-glutamyl hydroxymethyl rhodamine green in the detection of peritoneal cancer metastases: Overcoming the problem of dilution when using a sprayable optical probe

Dynamic fluorescent imaging with the activatable probe, γ-glutamyl hydroxymethyl rhodamine green in the detection of peritoneal cancer metastases: Overcoming the problem of dilution when using a sprayable optical probe

https://doi.org/10.18632/oncotarget.9898

Yuko Nakamura, Toshiko Harada, Tadanobu Nagaya, Kazuhide Sato, Shuhei Okuyama, Peter L. Choyke,  and Hisataka Kobayashi
51124-51137
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Etoposide-Bevacizumab a new strategy against human melanoma cells expressing stem-like traits

Etoposide-Bevacizumab a new strategy against human melanoma cells expressing stem-like traits

https://doi.org/10.18632/oncotarget.9939

Maura Calvani, Francesca Bianchini, Maria Letizia Taddei, Matteo Becatti, Elisa Giannoni, Paola Chiarugi,  and Lido Calorini
51138-51149
Abstract  |  PDF  |  HTML  |  Order a Reprint

Oncogene FOXK1 enhances invasion of colorectal carcinoma by inducing epithelial-mesenchymal transition

Oncogene FOXK1 enhances invasion of colorectal carcinoma by inducing epithelial-mesenchymal transition

https://doi.org/10.18632/oncotarget.9457

Yao Wu, Ying Peng, Meiyan Wu, Wenjing Zhang, Mengnan Zhang, Ruyi Xie, Pei Zhang, Yang Bai, Jinjun Zhao, Aimin Li, Qingzhen Nan, Ye Chen, Yuexin Ren, Side Liu,  and Jide Wang
51150-51162
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

An essential pathway links FLT3-ITD, HCK and CDK6 in acute myeloid leukemia

An essential pathway links FLT3-ITD, HCK and CDK6 in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.9965

Sophie Lopez, Edwige Voisset, Julie C. Tisserand, Cyndie Mosca, Thomas Prebet, David Santamaria, Patrice Dubreuil,  and Paulo De Sepulveda
51163-51173
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RNF216 contributes to proliferation and migration of colorectal cancer via suppressing BECN1-dependent autophagy

RNF216 contributes to proliferation and migration of colorectal cancer via suppressing BECN1-dependent autophagy

https://doi.org/10.18632/oncotarget.9433

Hui Wang, Yanan Wang, Liu Qian, Xue Wang, Hailiang Gu, Xiaoqiang Dong, Shiqian Huang, Min Jin, Hailiang Ge, Congfeng Xu,  and Yanyun Zhang
51174-51183
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impact of autoimmune diseases on outcome of patients with early breast cancer

Impact of autoimmune diseases on outcome of patients with early breast cancer

https://doi.org/10.18632/oncotarget.9966

Carmen Criscitiello, Vincenzo Bagnardi, Angela Esposito, Lucia Gelao, Barbara Santillo, Giulia Viale, Nicole Rotmensz, Aron Goldhirsch,  and Giuseppe Curigliano
51184-51192
Abstract  |  PDF  |  HTML  |  Order a Reprint

Hexavalent chromium induces malignant transformation of human lung bronchial epithelial cells via ROS-dependent activation of miR-21-PDCD4 signaling

Hexavalent chromium induces malignant transformation of human lung bronchial epithelial cells via ROS-dependent activation of miR-21-PDCD4 signaling

https://doi.org/10.18632/oncotarget.9967

Poyil Pratheeshkumar, Young-Ok Son, Sasidharan Padmaja Divya, Lilia Turcios, Ram Vinod Roy, John Andrew Hitron, Lei Wang, Donghern Kim, Jin Dai, Padmaja Asha, Zhuo Zhang,  and Xianglin Shi
51193-51210
Abstract  |  PDF  |  HTML  |  Order a Reprint

The non-coding landscape of head and neck squamous cell carcinoma

The non-coding landscape of head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.9979

Angela E. Zou, Hao Zheng, Maarouf A. Saad, Mehran Rahimy, Jonjei Ku, Selena Z. Kuo, Thomas K. Honda, Jessica Wang-Rodriguez, Yinan Xuan, Avinaash Korrapati, Vicky Yu, Pranav Singh, Jennifer R. Grandis, Charles C. King, Scott M. Lippman, Xiao Qi Wang, Andrew Hinton,  and Weg M. Ongkeko
51211-51222
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-495 inhibits esophageal squamous cell carcinoma progression by targeting Akt1

MiR-495 inhibits esophageal squamous cell carcinoma progression by targeting Akt1

https://doi.org/10.18632/oncotarget.9981

Yu Mao, Liang Li, Jia Liu, Le Wang,  and Yan Zhou
51223-51236
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value and their clinical implication of 89-gene signature in glioma

Prognostic value and their clinical implication of 89-gene signature in glioma

https://doi.org/10.18632/oncotarget.9983

Muhammad Shahid, Kyoung Min Cho, Minh Nam Nguyen, Tae Gyu Choi, Yong Hwa Jo, Saurav Nath Aryal, Ji Youn Yoo, Hyeong Rok Yun, Jae Woong Lee, Young Gyu Eun, Ju-Seog Lee, Insug Kang, Joohun Ha, Hwi-Joong Yoon, Si-Young Kim,  and Sung Soo Kim
51237-51250
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Icaritin, a novel FASN inhibitor, exerts anti-melanoma activities through IGF-1R/STAT3 signaling

Icaritin, a novel FASN inhibitor, exerts anti-melanoma activities through IGF-1R/STAT3 signaling

https://doi.org/10.18632/oncotarget.9984

Jinfeng Wu, Juan Du, Xiuqiong Fu, Bin Liu, Huihui Cao, Ting Li, Tao Su, Jinhua Xu, Anfernee Kai-Wing Tse,  and Zhi-Ling Yu
51251-51269
Abstract  |  PDF  |  HTML  |  Order a Reprint

iPhos-PseEn: Identifying phosphorylation sites in proteins by fusing different pseudo components into an ensemble classifier

iPhos-PseEn: Identifying phosphorylation sites in proteins by fusing different pseudo components into an ensemble classifier

https://doi.org/10.18632/oncotarget.9987

Wang-Ren Qiu, Xuan Xiao, Zhao-Chun Xu,  and Kuo-Chen Chou
51270-51283
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Androgen-induced miR-135a acts as a tumor suppressor through downregulating RBAK and MMP11, and mediates resistance to androgen deprivation therapy

Androgen-induced miR-135a acts as a tumor suppressor through downregulating RBAK and MMP11, and mediates resistance to androgen deprivation therapy

https://doi.org/10.18632/oncotarget.9992

Xuechao Wan, Honglei Pu, Wenhua Huang, Shu Yang, Yalong Zhang, Zhe Kong, Zhuoran Yang, Peiqing Zhao, Ao Li, Tao Li,  and Yao Li
51284-51300
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

P300 inhibition enhances gemcitabine-induced apoptosis of pancreatic cancer

P300 inhibition enhances gemcitabine-induced apoptosis of pancreatic cancer

https://doi.org/10.18632/oncotarget.10117

Hiroaki Ono, Marc D. Basson,  and Hiromichi Ito
51301-51310
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The coexistence of MET over-expression and an EGFR T790M mutation is related to acquired resistance to EGFR tyrosine kinase inhibitors in advanced non-small cell lung cancer

The coexistence of MET over-expression and an EGFR T790M mutation is related to acquired resistance to EGFR tyrosine kinase inhibitors in advanced non-small cell lung cancer

https://doi.org/10.18632/oncotarget.9697

Lan-Ying Gou, An-Na Li, Jin-Ji Yang, Xu-Chao Zhang, Jian Su, Hong-Hong Yan, Zhi Xie, Na-Na Lou, Si-Yang Liu, Zhong-Yi Dong, Hong-Fei Gao, Qing Zhou, Wen-Zhao Zhong, Chong-Rui Xu,  and Yi-Long Wu
51311-51319
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

16S rRNA amplicon sequencing identifies microbiota associated with oral cancer, human papilloma virus infection and surgical treatment

16S rRNA amplicon sequencing identifies microbiota associated with oral cancer, human papilloma virus infection and surgical treatment

https://doi.org/10.18632/oncotarget.9710

Rafael Guerrero-Preston, Filipa Godoy-Vitorino, Anne Jedlicka, Arnold Rodríguez-Hilario, Herminio González, Jessica Bondy, Fahcina Lawson, Oluwasina Folawiyo, Christina Michailidi, Amanda Dziedzic, Rajagowthamee Thangavel, Tal Hadar, Maartje G. Noordhuis, William Westra, Wayne Koch,  and David Sidransky
51320-51334
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Characterization of a P-Rex1 gene signature in breast cancer cells

Characterization of a P-Rex1 gene signature in breast cancer cells

https://doi.org/10.18632/oncotarget.10285

Laura Barrio-Real, Eva Wertheimer, Rachana Garg, Martin C. Abba,  and Marcelo G. Kazanietz
51335-51348
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Loss of insulin-like growth factor II imprinting is a hallmark associated with enhanced chemo/radiotherapy resistance in cancer stem cells

Loss of insulin-like growth factor II imprinting is a hallmark associated with enhanced chemo/radiotherapy resistance in cancer stem cells

https://doi.org/10.18632/oncotarget.9784

Xin Zhao, Xiaoliang Liu, Guanjun Wang, Xue Wen, Xiaoying Zhang, Andrew R. Hoffman, Wei Li, Ji-Fan Hu,  and Jiuwei Cui
51349-51364
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Associations between CYP1A1 rs1048943 A > G and rs4646903 T > C genetic variations and colorectal cancer risk: Proof from 26 case-control studies

Associations between CYP1A1 rs1048943 A > G and rs4646903 T > C genetic variations and colorectal cancer risk: Proof from 26 case-control studies

https://doi.org/10.18632/oncotarget.10331

Xueru Zhu, Zhao Wang, Jing He, Weiye Wang, Wenji Xue, Yiwei Wang, Leizhen Zheng,  and Mei-Ling Zhu
51365-51374
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TMPRSS2-ERG fusion protein regulates insulin-like growth factor-1 receptor (IGF1R) gene expression in prostate cancer: involvement of transcription factor Sp1

TMPRSS2-ERG fusion protein regulates insulin-like growth factor-1 receptor (IGF1R) gene expression in prostate cancer: involvement of transcription factor Sp1

https://doi.org/10.18632/oncotarget.9837

Shilhav Meisel Sharon, Yair Pozniak, Tamar Geiger,  and Haim Werner
51375-51392
Abstract  |  PDF  |  HTML  |  Order a Reprint

MiR-7a is an important mediator in Fas-associated protein with death domain (FADD)-regulated expression of focal adhesion kinase (FAK)

MiR-7a is an important mediator in Fas-associated protein with death domain (FADD)-regulated expression of focal adhesion kinase (FAK)

https://doi.org/10.18632/oncotarget.9838

Yingting Liu, Hongen Cui, Xianjie Huang, Bo Zhu, Shengwen Guan, Wei Cheng, Yueyang Lai, Xiaoxin Zhang,  and Zi-Chun Hua
51393-51407
Abstract  |  PDF  |  HTML  |  Order a Reprint

Novel cancer stem cell targets during epithelial to mesenchymal transition in PTEN-deficient trastuzumab-resistant breast cancer

Novel cancer stem cell targets during epithelial to mesenchymal transition in PTEN-deficient trastuzumab-resistant breast cancer

https://doi.org/10.18632/oncotarget.9839

Lichao Sun, Joseph Burnett, Mari Gasparyan, Fangying Xu, Hui Jiang, Chang-Ching Lin, Ila Myers, Hasan Korkaya, Yajing Liu, Jamie Connarn, Huining He, Ning Zhang, Max S. Wicha,  and Duxin Sun
51408-51422
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FOXC2 and CLIP4 : a potential biomarker for synchronous metastasis of ≤7-cm clear cell renal cell carcinomas

FOXC2 and CLIP4 : a potential biomarker for synchronous metastasis of ≤7-cm clear cell renal cell carcinomas

https://doi.org/10.18632/oncotarget.9842

Jinwoo Ahn, Kyung Seok Han, Jun Hyeok Heo, Duhee Bang, You Hyun Kang, Hyun A. Jin, Sung Joon Hong, Ji Hyun Lee,  and Won Sik Ham
51423-51434
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Biguanides sensitize leukemia cells to ABT-737-induced apoptosis by inhibiting mitochondrial electron transport

Biguanides sensitize leukemia cells to ABT-737-induced apoptosis by inhibiting mitochondrial electron transport

https://doi.org/10.18632/oncotarget.9843

Juliana Velez, Rongqing Pan, Jason T.C. Lee, Leonardo Enciso, Marta Suarez, Jorge Eduardo Duque, Daniel Jaramillo, Catalina Lopez, Ludis Morales, William Bornmann, Marina Konopleva, Gerald Krystal, Michael Andreeff,  and Ismael Samudio
51435-51449
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Improved therapeutic outcomes of thermal ablation on rat orthotopic liver allograft sarcoma models by radioiodinated hypericin induced necrosis targeted radiotherapy

Improved therapeutic outcomes of thermal ablation on rat orthotopic liver allograft sarcoma models by radioiodinated hypericin induced necrosis targeted radiotherapy

https://doi.org/10.18632/oncotarget.9848

Long Gao, Jian Zhang, Tengchuang Ma, Nan Yao, Meng Gao, Xin Shan, Yicheng Ni, Haibo Shao,  and Ke Xu
51450-51461
Abstract  |  PDF  |  HTML  |  Order a Reprint

Different metabolic responses to PI3K inhibition in NSCLC cells harboring wild-type and G12C mutant KRAS

Different metabolic responses to PI3K inhibition in NSCLC cells harboring wild-type and G12C mutant KRAS

https://doi.org/10.18632/oncotarget.9849

Elisa Caiola, Laura Brunelli, Mirko Marabese, Massimo Broggini, Monica Lupi,  and Roberta Pastorelli
51462-51472
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long non-coding RNA-H19 antagonism protects against renal fibrosis

Long non-coding RNA-H19 antagonism protects against renal fibrosis

https://doi.org/10.18632/oncotarget.10444

Hong Xie, Jing-Dong Xue, Feng Chao, Yan-Feng Jin,  and Qiang Fu
51473-51481
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-17-5p regulated apoptosis-related protein expression and radiosensitivity in oral squamous cell carcinoma caused by betel nut chewing

MicroRNA-17-5p regulated apoptosis-related protein expression and radiosensitivity in oral squamous cell carcinoma caused by betel nut chewing

https://doi.org/10.18632/oncotarget.9856

Szu-Yuan Wu, Alexander T.H. Wu,  and Shing-Hwa Liu
51482-51493
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clonal evolution in relapsed and refractory diffuse large B-cell lymphoma is characterized by high dynamics of subclones

Clonal evolution in relapsed and refractory diffuse large B-cell lymphoma is characterized by high dynamics of subclones

https://doi.org/10.18632/oncotarget.9860

Thomas Melchardt, Clemens Hufnagl, David M. Weinstock, Nadja Kopp, Daniel Neureiter, Wolfgang Tränkenschuh, Hubert Hackl, Lukas Weiss, Gabriel Rinnerthaler, Tanja N. Hartmann, Richard Greil, Oliver Weigert,  and Alexander Egle
51494-51502
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Induction of HOXA9 expression in three-dimensional organotypic culture of the Claudin-low breast cancer cells

Induction of HOXA9 expression in three-dimensional organotypic culture of the Claudin-low breast cancer cells

https://doi.org/10.18632/oncotarget.10491

Miao Li, Xi Li, Yan Zhuang, Yan Wang, Matthew E. Burow, Bridgette Collins-Burow, Min Xue, Chengjie Song,  and Bin Shan
51503-51514
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

YKT6 expression, exosome release, and survival in non-small cell lung cancer

YKT6 expression, exosome release, and survival in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.9862

Marc Ruiz-Martinez, Alfons Navarro, Ramón M. Marrades, Nuria Viñolas, Sandra Santasusagna, Carmen Muñoz, Josep Ramírez, Laureano Molins,  and Mariano Monzo
51515-51524
Abstract  |  PDF  |  HTML  |  Order a Reprint

CCL2/CCR2 axis is associated with postoperative survival and recurrence of patients with non-metastatic clear-cell renal cell carcinoma

CCL2/CCR2 axis is associated with postoperative survival and recurrence of patients with non-metastatic clear-cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.10492

Zewei Wang, Huyang Xie, Lin Zhou, Zheng Liu, Hangcheng Fu, Yu Zhu, Le Xu,  and Jiejie Xu
51525-51534
Abstract  |  PDF  |  HTML  |  Order a Reprint

Synthetic low-density lipoprotein (sLDL) selectively delivers paclitaxel to tumor with low systemic toxicity

Synthetic low-density lipoprotein (sLDL) selectively delivers paclitaxel to tumor with low systemic toxicity

https://doi.org/10.18632/oncotarget.10493

Hai-Tao Su, Xin Li, De-Sheng Liang,  and Xian-Rong Qi
51535-51552
Abstract  |  PDF  |  HTML  |  Order a Reprint

Motility and stem cell properties induced by the epithelial-mesenchymal transition require destabilization of lipid rafts

Motility and stem cell properties induced by the epithelial-mesenchymal transition require destabilization of lipid rafts

https://doi.org/10.18632/oncotarget.9928

Michael J. Tisza, Weina Zhao, Jessie S.R. Fuentes, Sara Prijic, Xiaoling Chen, Ilya Levental,  and Jeffrey T. Chang
51553-51568
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tris DBA palladium is highly effective against growth and metastasis of pancreatic cancer in an orthotopic model

Tris DBA palladium is highly effective against growth and metastasis of pancreatic cancer in an orthotopic model

https://doi.org/10.18632/oncotarget.10514

Begoña Díaz, Katherine T. Ostapoff, Jason E. Toombs, Jason Lo, Michael Y. Bonner, Adam Curatolo, Volkan Adsay, Rolf A. Brekken,  and Jack L. Arbiser
51569-51580
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Immunotherapy of acute leukemia by chimeric antigen receptor-modified lymphocytes using an improved Sleeping Beauty transposon platform

Immunotherapy of acute leukemia by chimeric antigen receptor-modified lymphocytes using an improved Sleeping Beauty transposon platform

https://doi.org/10.18632/oncotarget.9955

Chiara F. Magnani, Nice Turazzi, Fabrizio Benedicenti, Andrea Calabria, Erika Tenderini, Sarah Tettamanti, Greta M.P. Giordano Attianese, Laurence J.N. Cooper, Alessandro Aiuti, Eugenio Montini, Andrea Biondi,  and Ettore Biagi
51581-51597
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Is the Hong Kong Liver Cancer staging system the best guide for hepatitis B virus-related hepatocellular carcinoma patients with multiple tumors?

Is the Hong Kong Liver Cancer staging system the best guide for hepatitis B virus-related hepatocellular carcinoma patients with multiple tumors?

https://doi.org/10.18632/oncotarget.9956

Shuang Liu, Xiaoqiang Li, Hui Li, Lei Guo, Bo Zhang, Jubo Zhang,  and Qinghai Ye
51598-51607
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combined administration of fucoidan ameliorates tumor and chemotherapy-induced skeletal muscle atrophy in bladder cancer-bearing mice

Combined administration of fucoidan ameliorates tumor and chemotherapy-induced skeletal muscle atrophy in bladder cancer-bearing mice

https://doi.org/10.18632/oncotarget.9958

Meng-Chuan Chen, Wen-Lin Hsu, Pa-An Hwang, Yen-Lin Chen,  and Tz-Chong Chou
51608-51618
Abstract  |  PDF  |  HTML  |  Order a Reprint

Integrating heterogeneous drug sensitivity data from cancer pharmacogenomic studies

Integrating heterogeneous drug sensitivity data from cancer pharmacogenomic studies

https://doi.org/10.18632/oncotarget.10010

Nikita Pozdeyev, Minjae Yoo, Ryan Mackie, Rebecca E. Schweppe, Aik Choon Tan,  and Bryan R. Haugen
51619-51625
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Establishment and antitumor effects of dasatinib and PKI-587 in BD-138T, a patient-derived muscle invasive bladder cancer preclinical platform with concomitant EGFR amplification and PTEN deletion

Establishment and antitumor effects of dasatinib and PKI-587 in BD-138T, a patient-derived muscle invasive bladder cancer preclinical platform with concomitant EGFR amplification and PTEN deletion

https://doi.org/10.18632/oncotarget.10539

Nakho Chang, Hye Won Lee, Joung Eun Lim, Da Eun Jeong, Hye Jin Song, Sudong Kim, Do-Hyun Nam, Hyun Hwan Sung, Byong Chang Jeong, Seong Il Seo, Seong Soo Jeon, Hyun Moo Lee, Han-Yong Choi,  and Hwang Gyun Jeon
51626-51639
Abstract  |  PDF  |  HTML  |  Order a Reprint

Effect of JNK inhibitor SP600125 on hair cell regeneration in zebrafish (Danio rerio) larvae

Effect of JNK inhibitor SP600125 on hair cell regeneration in zebrafish (Danio rerio) larvae

https://doi.org/10.18632/oncotarget.10540

Yingzi He, Chengfu Cai, Shaoyang Sun, Xu Wang, Wenyan Li,  and Huawei Li
51640-51650
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cooperation of imipramine blue and tyrosine kinase blockade demonstrates activity against chronic myeloid leukemia

Cooperation of imipramine blue and tyrosine kinase blockade demonstrates activity against chronic myeloid leukemia

https://doi.org/10.18632/oncotarget.10541

Kamilla M.E. Laidlaw, Samuel Berhan, Suhu Liu, Giovannino Silvestri, Tessa L. Holyoake, David A. Frank, Bharat Aggarwal, Michael Y. Bonner, Danilo Perrotti, Heather G. Jørgensen,  and Jack L. Arbiser
51651-51664
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Secreted HMGB1 from Wnt activated intestinal cells is required to maintain a crypt progenitor phenotype

Secreted HMGB1 from Wnt activated intestinal cells is required to maintain a crypt progenitor phenotype

https://doi.org/10.18632/oncotarget.10076

Karen R. Reed, Fei Song, Maddy A. Young, Nurudeen Hassan, Daniel J. Antoine, Nesibe-Princess B. Gemici, Alan R. Clarke,  and John R. Jenkins
51665-51673
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epigenetic activation of MGAT3 and corresponding bisecting GlcNAc shortens the survival of cancer patients

Epigenetic activation of MGAT3 and corresponding bisecting GlcNAc shortens the survival of cancer patients

https://doi.org/10.18632/oncotarget.10543

Reto S. Kohler, Merrina Anugraham, Mónica Núñez López, Christina Xiao, Andreas Schoetzau, Timm Hettich, Goetz Schlotterbeck, André Fedier, Francis Jacob,  and Viola Heinzelmann-Schwarz
51674-51686
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Establishment and characterization of a penile cancer cell line, penl1, with a deleterious TP53 mutation as a paradigm of HPV-negative penile carcinogenesis

Establishment and characterization of a penile cancer cell line, penl1, with a deleterious TP53 mutation as a paradigm of HPV-negative penile carcinogenesis

https://doi.org/10.18632/oncotarget.10098

Jieping Chen, Kai Yao, Zaishang Li, Chuangzhong Deng, Liangjiao Wang, Xingsu Yu, Peili Liang, Qiankun Xie, Peng Chen, Zike Qin, Yunlin Ye, Zhuowei Liu, Fangjian Zhou, Zhenfeng Zhang,  and Hui Han
51687-51698
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Thyroid hormone synthesis: a potential target of a Chinese herbal formula Haizao Yuhu Decoction acting on iodine-deficient goiter

Thyroid hormone synthesis: a potential target of a Chinese herbal formula Haizao Yuhu Decoction acting on iodine-deficient goiter

https://doi.org/10.18632/oncotarget.10329

Yanqiong Zhang, Yuting Li, Xia Mao, Chen Yan, Xiaodong Guo, Qiuyan Guo, Zhenli Liu, Zhiqian Song,  and Na Lin
51699-51712
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long non-coding RNA TUG1 promotes colorectal cancer metastasis via EMT pathway

Long non-coding RNA TUG1 promotes colorectal cancer metastasis via EMT pathway

https://doi.org/10.18632/oncotarget.10563

Liang Wang, Zhenxian Zhao, Weidong Feng, Zhijun Ye, Weigang Dai, Changhua Zhang, Jianjun Peng,  and Kaiming Wu
51713-51719
Abstract  |  PDF  |  HTML  |  Order a Reprint

Protocadherin 17 functions as a tumor suppressor suppressing Wnt/β-catenin signaling and cell metastasis and is frequently methylated in breast cancer

Protocadherin 17 functions as a tumor suppressor suppressing Wnt/β-catenin signaling and cell metastasis and is frequently methylated in breast cancer

https://doi.org/10.18632/oncotarget.10102

Xuedong Yin, Tingxiu Xiang, Junhao Mu, Haitao Mao, Lili Li, Xin Huang, Chunhong Li, Yixiao Feng, Xinrong Luo, Yuxian Wei, Weiyan Peng, Guosheng Ren,  and Qian Tao
51720-51732
Abstract  |  PDF  |  HTML  |  Order a Reprint

Overexpression of semaphorin 3A promotes tumor progression and predicts poor prognosis in hepatocellular carcinoma after curative resection

Overexpression of semaphorin 3A promotes tumor progression and predicts poor prognosis in hepatocellular carcinoma after curative resection

https://doi.org/10.18632/oncotarget.10104

Zhi-Qiang Hu, Shao-Lai Zhou, Zheng-Jun Zhou, Chu-Bin Luo, Er-Bao Chen, Hao Zhan, Peng-Cheng Wang, Zhi Dai, Jian Zhou, Jia Fan,  and Xiao-Wu Huang
51733-51746
Abstract  |  PDF  |  HTML  |  Order a Reprint

Tamoxifen synergizes with 4-(E)-{(4-hydroxyphenylimino)-methylbenzene, 1,2-diol} and 4-(E)-{(p-tolylimino)-methylbenzene-1,2-diol}, novel azaresveratrol analogs, in inhibiting the proliferation of breast cancer cells

Tamoxifen synergizes with 4-(E)-{(4-hydroxyphenylimino)-methylbenzene, 1,2-diol} and 4-(E)-{(p-tolylimino)-methylbenzene-1,2-diol}, novel azaresveratrol analogs, in inhibiting the proliferation of breast cancer cells

https://doi.org/10.18632/oncotarget.10106

Amruta Ronghe, Anwesha Chatterjee, Nimee K. Bhat, Subhash Padhye,  and Hari K. Bhat
51747-51762
Abstract  |  PDF  |  HTML  |  Order a Reprint

Long non-coding RNA HULC as a novel serum biomarker for diagnosis and prognosis prediction of gastric cancer

Long non-coding RNA HULC as a novel serum biomarker for diagnosis and prognosis prediction of gastric cancer

https://doi.org/10.18632/oncotarget.10107

Chunjing Jin, Wei Shi, Feng Wang, Xianjuan Shen, Jing Qi, Hui Cong, Jie Yuan, Linying Shi, Bingying Zhu, Xi Luo, Yan Zhang,  and Shaoqing Ju
51763-51772
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Up-regulation of p16 by miR-877-3p inhibits proliferation of bladder cancer

Up-regulation of p16 by miR-877-3p inhibits proliferation of bladder cancer

https://doi.org/10.18632/oncotarget.10575

Shiqi Li, Yi Zhu, Zhen Liang, Xiao Wang, Shuai Meng, Xin Xu, Xianglai Xu, Jian Wu, Alin Ji, Zhenghui Hu, Yiwei Lin, Hong Chen, Yeqing Mao, Wei Wang, Xiangyi Zheng, Ben Liu,  and Liping Xie
51773-51783
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long non-coding RNA NEAT1 promotes non-small cell lung cancer progression through regulation of miR-377-3p-E2F3 pathway

Long non-coding RNA NEAT1 promotes non-small cell lung cancer progression through regulation of miR-377-3p-E2F3 pathway

https://doi.org/10.18632/oncotarget.10108

Chengcao Sun, Shujun Li, Feng Zhang, Yongyong Xi, Liang Wang, Yongyi Bi,  and Dejia Li
51784-51814
Abstract  |  PDF  |  HTML  |  Order a Reprint

E1A-engineered human umbilical cord mesenchymal stem cells as carriers and amplifiers for adenovirus suppress hepatocarcinoma in mice

E1A-engineered human umbilical cord mesenchymal stem cells as carriers and amplifiers for adenovirus suppress hepatocarcinoma in mice

https://doi.org/10.18632/oncotarget.10122

Zhenzhen Li, Zhou Ye, Xiaolong Zhang, Qing Zhang, Dongmei Fan, Yanjun Zhang, Hongbo R. Luo, Xiangfei Yuan, Zongfang Li,  and Dongsheng Xiong
51815-51828
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ARHGAP24 inhibits cell cycle progression, induces apoptosis and suppresses invasion in renal cell carcinoma

ARHGAP24 inhibits cell cycle progression, induces apoptosis and suppresses invasion in renal cell carcinoma

https://doi.org/10.18632/oncotarget.10386

Gaosi Xu, Xiongbing Lu, Tianlun Huang,  and Jie Fan
51829-51839
Abstract  |  PDF  |  HTML  |  Order a Reprint

Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the accumulation and functional activity of myeloid-derived suppressor cells (MDSCs) in pancreatic cancer

Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the accumulation and functional activity of myeloid-derived suppressor cells (MDSCs) in pancreatic cancer

https://doi.org/10.18632/oncotarget.10123

Jinhoi Song, Jaemin Lee, Jinsil Kim, Seongyea Jo, Yeon Jeong Kim, Ji Eun Baek, Eun-Soo Kwon, Kwang-Pyo Lee, Siyoung Yang, Ki-Sun Kwon, Dong-Uk Kim, Tae Heung Kang, Yun-Yong Park, Suhwan Chang, Hee Jun Cho, Song Cheol Kim, Sang Seok Koh,  and Seokho Kim
51840-51853
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of endoplasmic reticulum (ER) stress sensors sensitizes cancer stem-like cells to ER stress-mediated apoptosis

Inhibition of endoplasmic reticulum (ER) stress sensors sensitizes cancer stem-like cells to ER stress-mediated apoptosis

https://doi.org/10.18632/oncotarget.10126

Asaha Fujimoto, Kei Kawana, Ayumi Taguchi, Katsuyuki Adachi, Masakazu Sato, Hiroe Nakamura, Juri Ogishima, Mitsuyo Yoshida, Tomoko Inoue, Haruka Nishida, Kensuke Tomio, Aki Yamashita, Yoko Matsumoto, Takahide Arimoto, Osamu Wada-Hiraike, Katsutoshi Oda, Takeshi Nagamatsu, Yutaka Osuga,  and Tomoyuki Fujii
51854-51864
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MMP16 is a marker of poor prognosis in gastric cancer promoting proliferation and invasion

MMP16 is a marker of poor prognosis in gastric cancer promoting proliferation and invasion

https://doi.org/10.18632/oncotarget.10177

Li Cao, Chaowu Chen, Haihang Zhu, Xuewen Gu, Denghao Deng, Xiuchun Tian, Jun Liu,  and Qin Xiao
51865-51874
Abstract  |  PDF  |  HTML  |  Order a Reprint

A key role for transketolase-like 1 in tumor metabolic reprogramming

A key role for transketolase-like 1 in tumor metabolic reprogramming

https://doi.org/10.18632/oncotarget.10429

Santiago Diaz-Moralli, Esther Aguilar, Silvia Marin, Johannes F. Coy, Mieke Dewerchin, Maciek R. Antoniewicz, Oscar Meca-Cortés, Leen Notebaert, Bart Ghesquière, Guy Eelen, Timothy M. Thomson, Peter Carmeliet,  and Marta Cascante
51875-51897
Abstract  |  PDF  |  HTML  |  Order a Reprint

Molecular gene signature and prognosis of non-small cell lung cancer

Molecular gene signature and prognosis of non-small cell lung cancer

https://doi.org/10.18632/oncotarget.10622

Poyin Huang, Chiou-Ling Cheng, Ya-Hsuan Chang, Chia-Hsin Liu, Yi-Chiung Hsu, Jin-Shing Chen, Gee-Chen Chang, Bing-Ching Ho, Kang-Yi Su, Hsuan-Yu Chen,  and Sung-Liang Yu
51898-51907
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The anticancer phytochemical rocaglamide inhibits Rho GTPase activity and cancer cell migration

The anticancer phytochemical rocaglamide inhibits Rho GTPase activity and cancer cell migration

https://doi.org/10.18632/oncotarget.10188

Michael S. Becker, Paul M. Müller, Jörg Bajorat, Anne Schroeder, Marco Giaisi, Ehsan Amin, Mohammad R. Ahmadian, Oliver Rocks, Rebecca Köhler, Peter H. Krammer,  and Min Li-Weber
51908-51921
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

YAP promotes erlotinib resistance in human non-small cell lung cancer cells

YAP promotes erlotinib resistance in human non-small cell lung cancer cells

https://doi.org/10.18632/oncotarget.10458

Ping-Chih Hsu, Bin You, Yi-Lin Yang, Wen-Qian Zhang, Yu-Cheng Wang, Zhidong Xu, Yuyuan Dai, Shu Liu, Cheng-Ta Yang, Hui Li, Bin Hu, David M. Jablons,  and Liang You
51922-51933
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The antibiotic chloramphenicol may be an effective new agent for inhibiting the growth of multiple myeloma

The antibiotic chloramphenicol may be an effective new agent for inhibiting the growth of multiple myeloma

https://doi.org/10.18632/oncotarget.10623

Faqing Tian, Chunyan Wang, Meiqin Tang, Juheng Li, Xiaohui Cheng, Sihan Zhang, Delan Ji, Yingcai Huang,  and Huiqing Li
51934-51942
Abstract  |  PDF  |  HTML  |  Order a Reprint

MiR-27a-3p functions as an oncogene in gastric cancer by targeting BTG2

MiR-27a-3p functions as an oncogene in gastric cancer by targeting BTG2

https://doi.org/10.18632/oncotarget.10460

Lin Zhou, Xin Liang, Lingling Zhang, Liyan Yang, Norio Nagao, Hongkun Wu, Chang Liu, Shengchao Lin, Guoxiang Cai,  and Jianwen Liu
51943-51954
Abstract  |  PDF  |  HTML  |  Order a Reprint

ST6Gal-I modulates docetaxel sensitivity in human hepatocarcinoma cells via the p38 MAPK/caspase pathway

ST6Gal-I modulates docetaxel sensitivity in human hepatocarcinoma cells via the p38 MAPK/caspase pathway

https://doi.org/10.18632/oncotarget.10192

Xixi Chen, Liping Wang, Yujie Zhao, Shiqi Yuan, Qiang Wu, Xiaoling Zhu, Bachir Niang, Shujing Wang,  and Jianing Zhang
51955-51964
Abstract  |  PDF  |  HTML  |  Order a Reprint

Inhibition of the glucocorticoid receptor results in an enhanced miR-99a/100-mediated radiation response in stem-like cells from human prostate cancers

Inhibition of the glucocorticoid receptor results in an enhanced miR-99a/100-mediated radiation response in stem-like cells from human prostate cancers

https://doi.org/10.18632/oncotarget.10207

Jayant K. Rane, Holger H.H. Erb, Giovanna Nappo, Vincent M. Mann, Matthew S. Simms, Anne T. Collins, Tapio Visakorpi,  and Norman J. Maitland
51965-51980
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Adult T-cell leukemia/lymphoma in the Caribbean cohort is a distinct clinical entity with dismal response to conventional chemotherapy

Adult T-cell leukemia/lymphoma in the Caribbean cohort is a distinct clinical entity with dismal response to conventional chemotherapy

https://doi.org/10.18632/oncotarget.10223

Monica Zell, Amer Assal, Olga Derman, Noah Kornblum, Ramakrishna Battini, Yanhua Wang, Deepa M. Narasimhulu, Ioannis Mantzaris, Aditi Shastri, Amit Verma, Hilda Ye, Ira Braunschweig,  and Murali Janakiram
51981-51990
Abstract  |  PDF  |  HTML  |  Order a Reprint

Barriers to horizontal cell transformation by extracellular vesicles containing oncogenic H-ras

Barriers to horizontal cell transformation by extracellular vesicles containing oncogenic H-ras

https://doi.org/10.18632/oncotarget.10627

Tae Hoon Lee, Shilpa Chennakrishnaiah, Brian Meehan, Laura Montermini, Delphine Garnier, Esterina D'Asti, Wenyang Hou, Nathalie Magnus, Tenzin Gayden, Nada Jabado, Kolja Eppert, Loydie Majewska,  and Janusz Rak
51991-52002
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Osteopontin-a splice variant is overexpressed in papillary thyroid carcinoma and modulates invasive behavior

Osteopontin-a splice variant is overexpressed in papillary thyroid carcinoma and modulates invasive behavior

https://doi.org/10.18632/oncotarget.10468

Luciana Bueno Ferreira, Catarina Tavares, Ana Pestana, Catarina Leite Pereira, Catarina Eloy, Marta Teixeira Pinto, Patricia Castro, Rui Batista, Elisabete Rios, Manuel Sobrinho-Simões, Etel Rodrigues Pereira Gimba,  and Paula Soares
52003-52016
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Divergent in vitro/in vivo responses to drug treatments of highly aggressive NIH-Ras cancer cells: a PET imaging and metabolomics-mass-spectrometry study

Divergent in vitro/in vivo responses to drug treatments of highly aggressive NIH-Ras cancer cells: a PET imaging and metabolomics-mass-spectrometry study

https://doi.org/10.18632/oncotarget.10470

Daniela Gaglio, Silvia Valtorta, Marilena Ripamonti, Marcella Bonanomi, Chiara Damiani, Sergio Todde, Alfredo Simone Negri, Francesca Sanvito, Fabrizia Mastroianni, Antonella Di Campli, Gabriele Turacchio, Giuseppe Di Grigoli, Sara Belloli, Alberto Luini, Maria Carla Gilardi, Anna Maria Colangelo, Lilia Alberghina,  and Rosa Maria Moresco
52017-52031
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

sTLR4/MD-2 complex inhibits colorectal cancer in vitro and in vivo by targeting LPS

sTLR4/MD-2 complex inhibits colorectal cancer in vitro and in vivo by targeting LPS

https://doi.org/10.18632/oncotarget.10496

Yan Zou, Fengxian Qin, Jifei Chen, Jie Meng, Liuhua Wei, Chunlin Wu, Qiaoyun Zhang, Dong Wei, Xiang Chen, Hao Wu, Xiaoli Chen,  and Shengming Dai
52032-52044
Abstract  |  PDF  |  HTML  |  Order a Reprint

The dual role of asporin in breast cancer progression

The dual role of asporin in breast cancer progression

https://doi.org/10.18632/oncotarget.10471

Dana Simkova, Gvantsa Kharaishvili, Gabriela Korinkova, Tomas Ozdian, Tereza Suchánková-Kleplová, Tomas Soukup, Michal Krupka, Adela Galandakova, Petr Dzubak, Maria Janikova, Jiri Navratil, Zuzana Kahounova, Karel Soucek,  and Jan Bouchal
52045-52060
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hypoxia-mediated alterations and their role in the HER-2/neuregulated CREB status and localization

Hypoxia-mediated alterations and their role in the HER-2/neuregulated CREB status and localization

https://doi.org/10.18632/oncotarget.10474

André Steven, Sandra Leisz, Katharina Sychra, Bernhard Hiebl, Claudia Wickenhauser, Dimitrios Mougiakakos, Rolf Kiessling, Carsten Denkert,  and Barbara Seliger
52061-52084
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Lgr5+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors

Lgr5+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors

https://doi.org/10.18632/oncotarget.10475

Gerline C. van de Glind, Jacoba J. Out-Luiting, Heggert G. Rebel, Cornelis P. Tensen,  and Frank R. de Gruijl
52085-52094
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pre- and post-diagnosis physical activity is associated with survival benefits of colorectal cancer patients: a systematic review and meta-analysis

Pre- and post-diagnosis physical activity is associated with survival benefits of colorectal cancer patients: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.10603

Wenrui Wu, Feifei Guo, Jianzhong Ye, Yating Li, Ding Shi, Daiqiong Fang, Jing Guo,  and Lanjuan Li
52095-52103
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-93-5p may participate in the formation of morphine tolerance in bone cancer pain mouse model by targeting Smad5

MicroRNA-93-5p may participate in the formation of morphine tolerance in bone cancer pain mouse model by targeting Smad5

https://doi.org/10.18632/oncotarget.10524

Wen-Feng Xiao, Yu-Sheng Li, Wei Lou, Ting Cai, Shun Zhang, Xiao-Ying Hu, Xing-Wang Zhang,  and Wei Luo
52104-52114
Abstract  |  PDF  |  HTML  |  Order a Reprint

Combined genetic and epigenetic interferences with interferon signaling expose prostate cancer cells to viral infection

Combined genetic and epigenetic interferences with interferon signaling expose prostate cancer cells to viral infection

https://doi.org/10.18632/oncotarget.10313

Oded Danziger, Ben Shai, Yosef Sabo, Eran Bacharach,  and Marcelo Ehrlich
52115-52134
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The natural dietary genistein boosts bacteriophage-mediated cancer cell killing by improving phage-targeted tumor cell transduction

The natural dietary genistein boosts bacteriophage-mediated cancer cell killing by improving phage-targeted tumor cell transduction

https://doi.org/10.18632/oncotarget.10662

Effrosyni Tsafa, Mariam Al-Bahrani, Kaoutar Bentayebi, Justyna Przystal, Keittisak Suwan,  and Amin Hajitou
52135-52149
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

YAP and 14-3-3γ are involved in HS-OA-induced growth inhibition of hepatocellular carcinoma cells: A novel mechanism for hydrogen sulfide releasing oleanolic acid

YAP and 14-3-3γ are involved in HS-OA-induced growth inhibition of hepatocellular carcinoma cells: A novel mechanism for hydrogen sulfide releasing oleanolic acid

https://doi.org/10.18632/oncotarget.10663

Guanglin Xu, Jing Wang, Fangfang Wu, Na Wang, Wenli Zhou, Qian Wang, Wang Pan, Guizhen Ao,  and Jiquan Yang
52150-52165
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner

A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner

https://doi.org/10.18632/oncotarget.10700

Selina K. Sutton, Daniel R. Carter, Patrick Kim, Owen Tan, Greg M. Arndt, Xu Dong Zhang, Jonathan Baell, Benjamin D. Noll, Shudong Wang, Naresh Kumar, Grant A. McArthur, Belamy B. Cheung,  and Glenn M. Marshall
52166-52178
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Melatonin suppresses autophagy in type 2 diabetic osteoporosis

Melatonin suppresses autophagy in type 2 diabetic osteoporosis

https://doi.org/10.18632/oncotarget.10538

Wei-Lin Zhang, Hong-Zheng Meng, Rui-Fei Yang, Mao-Wei Yang, Guang-Hong Sun, Jun-Hua Liu, Peng-Xu Shi, Fei Liu,  and Bo Yang
52179-52194
Abstract  |  PDF  |  HTML  |  Order a Reprint

Anti-proliferative and pro-apoptotic effects of GHRH antagonists in prostate cancer

Anti-proliferative and pro-apoptotic effects of GHRH antagonists in prostate cancer

https://doi.org/10.18632/oncotarget.10710

Laura Muñoz-Moreno, M. Isabel Arenas, María J. Carmena, Andrew V. Schally, Manuel Sánchez-Chapado, Juan C. Prieto,  and Ana M. Bajo
52195-52206
Abstract  |  PDF  |  HTML  |  Order a Reprint

A folate receptor-targeted lipoplex delivering interleukin-15 gene for colon cancer immunotherapy

A folate receptor-targeted lipoplex delivering interleukin-15 gene for colon cancer immunotherapy

https://doi.org/10.18632/oncotarget.10537

Xiao Liang, Min Luo, Xia-Wei Wei, Cui-Cui Ma, Yu-Han Yang, Bin Shao, Yan-Tong Liu, Ting Liu, Jun Ren, Li Liu, Zhi-Yao He,  and Yu-Quan Wei
52207-52217
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Icariside II overcomes TRAIL resistance of melanoma cells through ROS-mediated downregulation of STAT3/cFLIP signaling

Icariside II overcomes TRAIL resistance of melanoma cells through ROS-mediated downregulation of STAT3/cFLIP signaling

https://doi.org/10.18632/oncotarget.10582

Juan Du, Jinfeng Wu, Xiuqiong Fu, Anfernee Kai-Wing Tse, Ting Li, Tao Su,  and Zhi-ling Yu
52218-52229
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Controlled release strategy of paclitaxel by conjugating to matrix metalloproteinases-2 sensitive peptide

Controlled release strategy of paclitaxel by conjugating to matrix metalloproteinases-2 sensitive peptide

https://doi.org/10.18632/oncotarget.10735

Changjiang Huang, Xiulin Yi, Dexin Kong, Ligong Chen,  and Gong Min
52230-52238
Abstract  |  PDF  |  HTML  |  Order a Reprint

VPS34 regulates TSC1/TSC2 heterodimer to mediate RheB and mTORC1/S6K1 activation and cellular transformation

VPS34 regulates TSC1/TSC2 heterodimer to mediate RheB and mTORC1/S6K1 activation and cellular transformation

https://doi.org/10.18632/oncotarget.10469

Nishant Mohan, Yi Shen, Milos Dokmanovic, Yukinori Endo, Dianne S. Hirsch,  and Wen Jin Wu
52239-52254
Abstract  |  PDF  |  HTML  |  Order a Reprint

PATZ1 induces PP4R2 to form a negative feedback loop on IKK/NF-κB signaling in lung cancer

PATZ1 induces PP4R2 to form a negative feedback loop on IKK/NF-κB signaling in lung cancer

https://doi.org/10.18632/oncotarget.10427

Ming-Yi Ho, Chi-Ming Liang,  and Shu-Mei Liang
52255-52269
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Bioinformatics facilitating the use of microarrays to delineate potential miRNA biomarkers in aristolochic acid nephropathy

Bioinformatics facilitating the use of microarrays to delineate potential miRNA biomarkers in aristolochic acid nephropathy

https://doi.org/10.18632/oncotarget.10586

Yana Lv, Yumei Que, Qiao Su, Qiang Li, Xi Chen,  and Haitao Lu
52270-52280
Abstract  |  PDF  |  HTML  |  Order a Reprint

Millepachine, a potential topoisomerase II inhibitor induces apoptosis via activation of NF-κB pathway in ovarian cancer

Millepachine, a potential topoisomerase II inhibitor induces apoptosis via activation of NF-κB pathway in ovarian cancer

https://doi.org/10.18632/oncotarget.10739

Wenshuang Wu, Buyun Ma, Haoyu Ye, Taijin Wang, Xiaoyan Wang, Jianhong Yang, Yuquan Wei, Jingqiang Zhu,  and Lijuan Chen
52281-52293
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype

TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype

https://doi.org/10.18632/oncotarget.10561

Fan Zhang, Hongsheng Wang, Xianfeng Wang, Guanmin Jiang, Hao Liu, Ge Zhang, Hao Wang, Rui Fang, Xianzhang Bu, Shaohui Cai,  and Jun Du
52294-52306
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metastatic spread in patients with gastric cancer

Metastatic spread in patients with gastric cancer

https://doi.org/10.18632/oncotarget.10740

Matias Riihimäki, Akseli Hemminki, Kristina Sundquist, Jan Sundquist,  and Kari Hemminki
52307-52316
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Proteomics-based identification of VDAC1 as a tumor promoter in cervical carcinoma

Proteomics-based identification of VDAC1 as a tumor promoter in cervical carcinoma

https://doi.org/10.18632/oncotarget.10562

Changlin Zhang, Wencheng Ding, Yuan Liu, Zheng Hu, Da Zhu, Xiaoli Wang, Lan Yu, Liming Wang, Hui Shen, Weican Zhang, Ci Ren, Kezhen Li, Danhui Weng, Wuguo Deng, Ding Ma,  and Hui Wang
52317-52328
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Up-regulation of fibroblast growth factor 19 and its receptor associates with progression from fatty liver to hepatocellular carcinoma

Up-regulation of fibroblast growth factor 19 and its receptor associates with progression from fatty liver to hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.10750

Yan Li, Weizhong Zhang, Anne Doughtie, Guozhen Cui, Xuanyi Li, Harshul Pandit, Yingbin Yang, Suping Li,  and Robert Martin
52329-52339
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-184 promotes differentiation of the retinal pigment epithelium by targeting the AKT2/mTOR signaling pathway

MicroRNA-184 promotes differentiation of the retinal pigment epithelium by targeting the AKT2/mTOR signaling pathway

https://doi.org/10.18632/oncotarget.10566

Chao Jiang, Bing Qin, Guohua Liu, Xiantao Sun, Houxia Shi, Sijia Ding, Yuan Liu, Meidong Zhu, Xue Chen,  and Chen Zhao
52340-52353
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preclinical activity of EGFR and MEK1/2 inhibitors in the treatment of biliary tract carcinoma

Preclinical activity of EGFR and MEK1/2 inhibitors in the treatment of biliary tract carcinoma

https://doi.org/10.18632/oncotarget.10587

Giuliana Cavalloni, Caterina Peraldo-Neia, Chiara Varamo, Giovanna Chiorino, Francesco Sassi, Massimo Aglietta,  and Francesco Leone
52354-52363
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metabotyping human endometrioid endometrial adenocarcinoma reveals an implication of endocannabinoid metabolism

Metabotyping human endometrioid endometrial adenocarcinoma reveals an implication of endocannabinoid metabolism

https://doi.org/10.18632/oncotarget.10564

Mariona Jové, Sònia Gatius, Andree Yeramian, Manuel Portero-Otin, Núria Eritja, Maria Santacana, Eva Colas, Maria Ruiz, Reinald Pamplona,  and Xavier Matias-Guiu
52364-52374
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Disruption of tumour-host communication by downregulation of LFA-1 reduces COX-2 and e-NOS expression and inhibits brain metastasis growth

Disruption of tumour-host communication by downregulation of LFA-1 reduces COX-2 and e-NOS expression and inhibits brain metastasis growth

https://doi.org/10.18632/oncotarget.10737

Manuel Sarmiento Soto, Emma R. O’Brien, Kleopatra Andreou, Simon F. Scrace, Rasheed Zakaria, Michael D. Jenkinson, Eric O’Neill,  and Nicola R. Sibson
52375-52391
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of SREBP increases gefitinib sensitivity in non-small cell lung cancer cells

Inhibition of SREBP increases gefitinib sensitivity in non-small cell lung cancer cells

https://doi.org/10.18632/oncotarget.10721

Jiajin Li, Hui Yan, Li Zhao, Wenzhi Jia, Hao Yang, Liu Liu, Xiang Zhou, Ping Miao, Xiaoguang Sun, Shaoli Song, Xiaoping Zhao, Jianjun Liu,  and Gang Huang
52392-52403
Abstract  |  PDF  |  HTML  |  Order a Reprint

Potential specific immunological indicators for stroke associated infection are partly modulated by sympathetic pathway activation

Potential specific immunological indicators for stroke associated infection are partly modulated by sympathetic pathway activation

https://doi.org/10.18632/oncotarget.10497

Huan Wang, Fu-Ling Yan, Michael Cunningham, Qi-Wen Deng, Lei Zuo, Fang-Lan Xing, Lu-Hang Shi, Shan-Shan Hu,  and Ya Huang
52404-52415
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

The role of CEUS in characterization of superficial lymph nodes: a single center prospective study

The role of CEUS in characterization of superficial lymph nodes: a single center prospective study

https://doi.org/10.18632/oncotarget.9385

Giorgio de Stefano, Umberto Scognamiglio, Filomena Di Martino, Roberto Parrella, Francesco Scarano, Giuseppe Signoriello,  and Nunzia Farella
52416-52422
Abstract  |  PDF  |  HTML  |  Order a Reprint

Histopathological investigation of glioblastomas resected under bevacizumab treatment

Histopathological investigation of glioblastomas resected under bevacizumab treatment

https://doi.org/10.18632/oncotarget.9387

Ryota Tamura, Toshihide Tanaka, Keisuke Miyake, Yusuke Tabei, Kentaro Ohara, Oltea Sampetrean, Maya Kono, Katsuhiro Mizutani, Yohei Yamamoto, Yuichi Murayama, Takashi Tamiya, Kazunari Yoshida,  and Hikaru Sasaki
52423-52435
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Intrapericardial bevacizumab safely and effectively treats malignant pericardial effusion in advanced cancer patients

Intrapericardial bevacizumab safely and effectively treats malignant pericardial effusion in advanced cancer patients

https://doi.org/10.18632/oncotarget.9420

Dawei Chen, Yan Zhang, Fang Shi, Hui Zhu, Minghuan Li, Kaijun Chen, Li Kong,  and Jinming Yu
52436-52441
Abstract  |  PDF  |  HTML  |  Order a Reprint

Relationship of smoking status to genomic profile, chemotherapy response and clinical outcome in patients with advanced urothelial carcinoma

Relationship of smoking status to genomic profile, chemotherapy response and clinical outcome in patients with advanced urothelial carcinoma

https://doi.org/10.18632/oncotarget.9449

Monika Joshi, Monali Vasekar, Petros Grivas, Hamid Emamekhoo, JoAnn Hsu, Vincent A. Miller, Philip J. Stephens, Siraj M. Ali, Jeffrey S. Ross, Junjia Zhu, Joshua Warrick, Joseph J. Drabick, Sheldon L. Holder, Matthew Kaag, Min Li,  and Sumanta Kumar Pal
52442-52449
Abstract  |  PDF  |  HTML  |  Order a Reprint

Characteristics and survival of patients with metachronous or synchronous double primary malignancies: breast and thyroid cancer

Characteristics and survival of patients with metachronous or synchronous double primary malignancies: breast and thyroid cancer

https://doi.org/10.18632/oncotarget.9547

Li Zhang, Yansheng Wu, Fangfang Liu, Li Fu,  and Zhongsheng Tong
52450-52459
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

Proteomics and peptidomics: moving toward precision medicine in urological malignancies

Proteomics and peptidomics: moving toward precision medicine in urological malignancies

https://doi.org/10.18632/oncotarget.8931

Ashley Di Meo, Maria D. Pasic,  and George M. Yousef
52460-52474
Abstract  |  PDF  |  HTML  |  Order a Reprint

miRNA expression and function in thyroid carcinomas: a comparative and critical analysis and a model for other cancers

miRNA expression and function in thyroid carcinomas: a comparative and critical analysis and a model for other cancers

https://doi.org/10.18632/oncotarget.9655

Manuel Saiselet, Jaime M. Pita, Alice Augenlicht, Geneviève Dom, Maxime Tarabichi, Danai Fimereli, Jacques E. Dumont, Vincent Detours,  and Carine Maenhaut
52475-52492
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Practical aspects of NGS-based pathways analysis for personalized cancer science and medicine

Practical aspects of NGS-based pathways analysis for personalized cancer science and medicine

https://doi.org/10.18632/oncotarget.9370

Ekaterina A. Kotelnikova, Mikhail Pyatnitskiy, Anna Paleeva, Olga Kremenetskaya,  and Dmitriy Vinogradov
52493-52516
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dietary phytochemicals and cancer chemoprevention: a review of the clinical evidence

Dietary phytochemicals and cancer chemoprevention: a review of the clinical evidence

https://doi.org/10.18632/oncotarget.9593

Ritesh Kotecha, Akiyoshi Takami,  and J. Luis Espinoza
52517-52529
Abstract  |  PDF  |  HTML  |  Order a Reprint

Association between the APEX1 Asp148Glu polymorphism and prostate cancer, especially among Asians: a new evidence-based analysis

Association between the APEX1 Asp148Glu polymorphism and prostate cancer, especially among Asians: a new evidence-based analysis

https://doi.org/10.18632/oncotarget.9693

Yang Chen, Jie Li,  and Zengnan Mo
52530-52540
Abstract  |  PDF  |  HTML  |  Order a Reprint

CRISPR/Cas9 therapeutics: a cure for cancer and other genetic diseases

CRISPR/Cas9 therapeutics: a cure for cancer and other genetic diseases

https://doi.org/10.18632/oncotarget.9646

Faheem Ahmed Khan, Nuruliarizki Shinta Pandupuspitasari, Huang Chun-Jie, Zhou Ao, Muhammad Jamal, Ali Zohaib, Farhan Ahmed Khan, Muthia Raihana Hakim,  and Zhang ShuJun
52541-52552
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeting folate receptor alpha for cancer treatment

Targeting folate receptor alpha for cancer treatment

https://doi.org/10.18632/oncotarget.9651

Anthony Cheung, Heather J. Bax, Debra H. Josephs, Kristina M. Ilieva, Giulia Pellizzari, James Opzoomer, Jacinta Bloomfield, Matthew Fittall, Anita Grigoriadis, Mariangela Figini, Silvana Canevari, James F. Spicer, Andrew N. Tutt,  and Sophia N. Karagiannis
52553-52574
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeting microenvironment in cancer therapeutics

Targeting microenvironment in cancer therapeutics

https://doi.org/10.18632/oncotarget.9824

Matthew Martin, Han Wei,  and Tao Lu
52575-52583
Abstract  |  PDF  |  HTML  |  Order a Reprint

Genetic and molecular alterations in olfactory neuroblastoma: implications for pathogenesis, prognosis and treatment

Genetic and molecular alterations in olfactory neuroblastoma: implications for pathogenesis, prognosis and treatment

https://doi.org/10.18632/oncotarget.9683

Piotr Czapiewski, Michał Kunc,  and Johannes Haybaeck
52584-52596
Abstract  |  PDF  |  HTML  |  Order a Reprint

FAM83 proteins: Fostering new interactions to drive oncogenic signaling and therapeutic resistance

FAM83 proteins: Fostering new interactions to drive oncogenic signaling and therapeutic resistance

https://doi.org/10.18632/oncotarget.9544

Courtney A. Bartel, Neetha Parameswaran, Rocky Cipriano,  and Mark W. Jackson
52597-52612
Abstract  |  PDF  |  HTML  |  Order a Reprint

Corrections

Correction: Polarized cell migration induces cancer type-specific CD133/integrin/Src/Akt/GSK3β/β-catenin signaling required for maintenance of cancer stem cell properties

Correction: Polarized cell migration induces cancer type-specific CD133/integrin/Src/Akt/GSK3β/β-catenin signaling required for maintenance of cancer stem cell properties

https://doi.org/10.18632/oncotarget.11119

Ying-Jhen Su, Wei-Hsin Lin, Yi-Wen Chang, Kuo-Chen Wei, Chi-Jung Liang, Shin-Cheh Chen,  and Jia-Lin Lee
52613
Correction  |  PDF


Copyright © 2017 Impact Journals
Impact Journals is a registered trademark of Impact Journals, LLC