Oncotarget

Vol 7, No 31

August 2, 2016

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Docking models of PIPbinding to proteins. See Ayyadevara et al.

Table of Contents

Editorial

Venous malformations: PIK3CA mutations guide new treatments

Venous malformations: PIK3CA mutations guide new treatments

https://doi.org/10.18632/oncotarget.9252

Hashem A. Dbouk
48852-48853
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CDK4/6 inhibition: the late harvest cycle begins

CDK4/6 inhibition: the late harvest cycle begins

https://doi.org/10.18632/oncotarget.9576

Shom Goel,  and Jean J. Zhao
48854-48856
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LIGHTing tumor up for checkpoint blockade

LIGHTing tumor up for checkpoint blockade

https://doi.org/10.18632/oncotarget.10531

Yong Liang,  and Hua Peng
48857-48858
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Editorial: Autophagy and Cell Death

mTOR signaling orchestrates the expression of cytoprotective factors during cellular senescence

mTOR signaling orchestrates the expression of cytoprotective factors during cellular senescence

https://doi.org/10.18632/oncotarget.10743

Reut Yosef,  and Valery Krizhanovsky
48859-48859
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Priority Research Papers

Circulating nano-particulate TLR9 agonist scouts out tumor microenvironment to release immunogenic dead tumor cells

Circulating nano-particulate TLR9 agonist scouts out tumor microenvironment to release immunogenic dead tumor cells

https://doi.org/10.18632/oncotarget.10379

Yuji Kitahata, Tomohiro Kanuma, Masayuki Hayashi, Nobuyoshi Kobayashi, Koji Ozasa, Takato Kusakabe, Burcu Temizoz, Etsushi Kuroda, Hiroki Yamaue, Cevayir Coban, Takuya Yamamoto, Kouji Kobiyama, Taiki Aoshi,  and Ken J. Ishii
48860-48869
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PIP3-binding proteins promote age-dependent protein aggregation and limit survival in C. elegans

PIP3-binding proteins promote age-dependent protein aggregation and limit survival in C. elegans

https://doi.org/10.18632/oncotarget.10549

Srinivas Ayyadevara, Meenakshisundaram Balasubramaniam, Jay Johnson, Ramani Alla, Samuel G. Mackintosh,  and Robert J. Shmookler Reis
48870-48886
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Research Papers: Gerotarget (Focus on Aging)

Amino acid-dependent signaling via S6K1 and MYC is essential for regulation of rDNA transcription

Amino acid-dependent signaling via S6K1 and MYC is essential for regulation of rDNA transcription

https://doi.org/10.18632/oncotarget.10346

Jian Kang, Eric P. Kusnadi, Allison J. Ogden, Rodney J. Hicks, Lukas Bammert, Ulrike Kutay, Sandy Hung, Elaine Sanij, Ross D. Hannan, Katherine M. Hannan,  and Richard B. Pearson
48887-48904
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Research Papers: Pathology

Early versus late distant metastasis and adjuvant chemotherapy alone versus both radiotherapy and chemotherapy in molecular apocrine breast cancer

Early versus late distant metastasis and adjuvant chemotherapy alone versus both radiotherapy and chemotherapy in molecular apocrine breast cancer

https://doi.org/10.18632/oncotarget.10211

Xiaozhen Liu, Yang Yang, Xiaolong Feng, Honghong Shen, Jian Liu, Xia Liu,  and Yun Niu
48905-48917
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Noninvasive ventilation improves cardiac function in patients with chronic heart failure

Noninvasive ventilation improves cardiac function in patients with chronic heart failure

https://doi.org/10.18632/oncotarget.10441

Jing Cheng, Yanping Liu, Guishuang Li, Zhongwen Zhang, Lianyue Ma, Xiaoyan Yang, Jianmin Yang, Kai Zhang, Jing Kong, Mei Dong, Meng Zhang, Xingli Xu, Wenhai Sui, Jiali Wang, Rui Shang, Xiaoping Ji, Yun Zhang, Cheng Zhang,  and Panpan Hao
48918-48924
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Mitochondrial transplantation attenuates hypoxic pulmonary hypertension

Mitochondrial transplantation attenuates hypoxic pulmonary hypertension

https://doi.org/10.18632/oncotarget.10596

Liping Zhu, Jiwei Zhang, Juan Zhou, Yankai Lu, Songling Huang, Rui Xiao, Xiangyuan Yu, Xianqin Zeng, Bingxun Liu, Fangbo Liu, Mengxiang Sun, Mao Dai, Qiang Hao, Jiansha Li, Tao Wang, Tongfei Li,  and Qinghua Hu
48925-48940
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Deciphering bacterial community changes in zucker diabetic fatty rats based on 16S rRNA gene sequences analysis

Deciphering bacterial community changes in zucker diabetic fatty rats based on 16S rRNA gene sequences analysis

https://doi.org/10.18632/oncotarget.10597

Chunyan Gu, Ye Yang, Hong Xiang, Shu Li, Lina Liang, Hua Sui, Libin Zhan,  and Xiaoguang Lu
48941-48952
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Abnormal organization of white matter networks in patients with subjective cognitive decline and mild cognitive impairment

Abnormal organization of white matter networks in patients with subjective cognitive decline and mild cognitive impairment

https://doi.org/10.18632/oncotarget.10601

Xiao-Ni Wang, Yang Zeng, Guan-Qun Chen, Yi-He Zhang, Xuan-Yu Li, Xu-Yang Hao, Yang Yu, Meng Zhang, Can Sheng, Yu-Xia Li, Yu Sun, Hong-Yan Li, Yang Song, Kun-Cheng Li, Tian-Yi Yan, Xiao-Ying Tang,  and Ying Han
48953-48962
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β-MSCs: successful fusion of MSCs with β-cells results in a β-cell like phenotype

β-MSCs: successful fusion of MSCs with β-cells results in a β-cell like phenotype

https://doi.org/10.18632/oncotarget.10214

Zahra Azizi, Claudia Lange, Federico Paroni, Amin Ardestani, Anke Meyer, Yonghua Wu, Axel R. Zander, Christof Westenfelder,  and Kathrin Maedler
48963-48977
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Research Papers: Immunology

MiR674 inhibits the neuraminidase-stimulated immune response on dendritic cells via down-regulated Mbnl3

MiR674 inhibits the neuraminidase-stimulated immune response on dendritic cells via down-regulated Mbnl3

https://doi.org/10.18632/oncotarget.9832

Jian Lin, Ya T. Chen, Jing Xia,  and Qian Yang
48978-48994
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Saikosaponin a inhibits LPS-induced inflammatory response by inducing liver X receptor alpha activation in primary mouse macrophages

Saikosaponin a inhibits LPS-induced inflammatory response by inducing liver X receptor alpha activation in primary mouse macrophages

https://doi.org/10.18632/oncotarget.9863

Zhengkai Wei, Jingjing Wang, Mingyu Shi, Weijian Liu, Zhengtao Yang,  and Yunhe Fu
48995-49007
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Identification of IFN-γ-producing T cells as the main mediators of the side effects associated to mouse interleukin-15 sustained exposure

Identification of IFN-γ-producing T cells as the main mediators of the side effects associated to mouse interleukin-15 sustained exposure

https://doi.org/10.18632/oncotarget.10264

Marianna Di Scala, Irene Gil-Fariña, Cristina Olagüe, Africa Vales, Luciano Sobrevals, Puri Fortes, David Corbacho,  and Gloria González-Aseguinolaza
49008-49026
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IRF3 is an important molecule in the UII/UT system and mediates immune inflammatory injury in acute liver failure

IRF3 is an important molecule in the UII/UT system and mediates immune inflammatory injury in acute liver failure

https://doi.org/10.18632/oncotarget.10717

Liang-ming Liu, Wen-juan Tu, Tong Zhu, Xiao-ting Wang, Zhi-li Tan, Huan Zhong, De-yong Gao,  and Dong-yu Liang
49027-49041
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Research Papers

Vitamin D3 suppresses morphological evolution of the cribriform cancerous phenotype

Vitamin D3 suppresses morphological evolution of the cribriform cancerous phenotype

https://doi.org/10.18632/oncotarget.8863

Ravi K. Deevi, Jane McClements, Karen D. McCloskey, Aliya Fatehullah, Dorota Tkocz, Arman Javadi, Robyn Higginson, Victoria Marsh Durban, Marnix Jansen, Alan Clarke, Maurice B. Loughrey,  and Frederick C. Campbell
49042-49064
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PCP4/PEP19 promotes migration, invasion and adhesion in human breast cancer MCF-7 and T47D cells

PCP4/PEP19 promotes migration, invasion and adhesion in human breast cancer MCF-7 and T47D cells

https://doi.org/10.18632/oncotarget.7529

Takuya Yoshimura, Taiji Hamada, Hiroshi Hijioka, Masakazu Souda, Kazuhito Hatanaka, Takako Yoshioka, Sohsuke Yamada, Masato Tsutsui, Yoshihisa Umekita, Norifumi Nakamura,  and Akihide Tanimoto
49065-49074
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Efficient therapeutic delivery by a novel cell-permeant peptide derived from KDM4A protein for antitumor and antifibrosis

Efficient therapeutic delivery by a novel cell-permeant peptide derived from KDM4A protein for antitumor and antifibrosis

https://doi.org/10.18632/oncotarget.8682

Hu Wang, Jie-Lan Ma, Ying-Gui Yang, Yang Song, Jiao Wu, Yan-Yan Qin, Xue-Li Zhao, Jun Wang, Li-Li Zou, Jiang-Feng Wu, Jun-Ming Li,  and Chang-Bai Liu
49075-49090
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Increased FGF19 copy number is frequently detected in hepatocellular carcinoma with a complete response after sorafenib treatment

Increased FGF19 copy number is frequently detected in hepatocellular carcinoma with a complete response after sorafenib treatment

https://doi.org/10.18632/oncotarget.10077

Masaki Kaibori, Kazuko Sakai, Morihiko Ishizaki, Hideyuki Matsushima, Marco A. De Velasco, Kosuke Matsui, Hiroya Iida, Hiroaki Kitade, A-Hon Kwon, Hiroaki Nagano, Hiroshi Wada, Seiji Haji, Tadashi Tsukamoto, Akishige Kanazawa, Yutaka Takeda, Shigekazu Takemura, Shoji Kubo,  and Kazuto Nishio
49091-49098
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A four gene signature of chromosome instability (CIN4) predicts for benefit from taxanes in the NCIC-CTG MA21 clinical trial

A four gene signature of chromosome instability (CIN4) predicts for benefit from taxanes in the NCIC-CTG MA21 clinical trial

https://doi.org/10.18632/oncotarget.8542

Melanie Spears, Nicola Lyttle, Alister D'Costa, Bingshu E. Chen, Cindy Q. Yao, Paul C. Boutros, Margot Burnell, Mark N. Levine, Patti O'Brien, Lois Shepherd,  and John M.S. Bartlett
49099-49106
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Functional role and tobacco smoking effects on methylation of CYP1A1 gene in prostate cancer

Functional role and tobacco smoking effects on methylation of CYP1A1 gene in prostate cancer

https://doi.org/10.18632/oncotarget.9470

Yozo Mitsui, Inik Chang, Taku Kato, Yutaka Hashimoto, Soichiro Yamamura, Shinichiro Fukuhara, Darryn K. Wong, Marisa Shiina, Mitsuho Imai-Sumida, Shahana Majid, Sharanjot Saini, Hiroaki Shiina, Koichi Nakajima, Guoren Deng, Rajvir Dahiya,  and Yuichiro Tanaka
49107-49121
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

X chromosome-wide identification of SNVs in microRNA genes and non-obstructive azoospermia risk in Han Chinese population

X chromosome-wide identification of SNVs in microRNA genes and non-obstructive azoospermia risk in Han Chinese population

https://doi.org/10.18632/oncotarget.8759

Juan Ji, Yufeng Qin, Ran Zhou, Rujin Zang, Zhenyao Huang, Yan Zhang, Minjian Chen, Wei Wu, Ling Song, Xiufeng Ling, Hongbing Shen, Zhibin Hu, Yankai Xia, Chuncheng Lu,  and Xinru Wang
49122-49129
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-224 inhibits proliferation and migration of breast cancer cells by down-regulating Frizzled 5 expression

MicroRNA-224 inhibits proliferation and migration of breast cancer cells by down-regulating Frizzled 5 expression

https://doi.org/10.18632/oncotarget.9734

Feng Liu, Yang Liu, Jingling Shen, Guoqiang Zhang,  and Jiguang Han
49130-49142
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Therapeutic strategy with artificially-designed i-lncRNA targeting multiple oncogenic microRNAs exhibits effective antitumor activity in diffuse large B-cell lymphoma

Therapeutic strategy with artificially-designed i-lncRNA targeting multiple oncogenic microRNAs exhibits effective antitumor activity in diffuse large B-cell lymphoma

https://doi.org/10.18632/oncotarget.9237

Yinghan Su, Bin Sun, Xuejing Lin, Xinying Zhao, Weidan Ji, Miaoxia He, Haihua Qian, Xianmin Song, Jianmin Yang, Jianmin Wang,  and Jie Chen
49143-49155
Abstract  |  PDF  |  HTML  |  Order a Reprint

Membranous CD24 drives the epithelial phenotype of pancreatic cancer

Membranous CD24 drives the epithelial phenotype of pancreatic cancer

https://doi.org/10.18632/oncotarget.9402

Clara Lubeseder-Martellato, Ana Hidalgo-Sastre, Carolin Hartmann, Katharina Alexandrow, Zahra Kamyabi-Moghaddam, Bence Sipos, Matthias Wirth, Florian Neff, Maximilian Reichert, Irina Heid, Günter Schneider, Rickmer Braren, Roland M. Schmid,  and Jens T. Siveke
49156-49168
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Androgen receptor activity modulates responses to cisplatin treatment in bladder cancer

Androgen receptor activity modulates responses to cisplatin treatment in bladder cancer

https://doi.org/10.18632/oncotarget.9994

Eiji Kashiwagi, Hiroki Ide, Satoshi Inoue, Takashi Kawahara, Yichun Zheng, Leonardo O. Reis, Alexander S. Baras,  and Hiroshi Miyamoto
49169-49179
Abstract  |  PDF  |  HTML  |  Order a Reprint

Inhibition of Cdc42 is essential for Mig-6 suppression of cell migration induced by EGF

Inhibition of Cdc42 is essential for Mig-6 suppression of cell migration induced by EGF

https://doi.org/10.18632/oncotarget.10205

Xinni Jiang, MengMeng Niu, Deshi Chen, Jing Chen, Yang Cao, Xiaorong Li, Haoqiang Ying, Johann Bergholz, Yujun Zhang,  and Zhi-Xiong Xiao
49180-49193
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease

Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease

https://doi.org/10.18632/oncotarget.10246

Maria M. Simile, Gavinella Latte, Maria I. Demartis, Stefania Brozzetti, Diego F. Calvisi, Alberto Porcu, Claudio F. Feo, Maria A. Seddaiu, Lucia Daino, Carmen Berasain, Maria L. Tomasi, Matias A. Avila, Francesco Feo,  and Rosa M. Pascale
49194-49216
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-223-5p works as an oncomiR in vulvar carcinoma by TP63 suppression

MiR-223-5p works as an oncomiR in vulvar carcinoma by TP63 suppression

https://doi.org/10.18632/oncotarget.10247

Beatriz de Melo Maia, Iara Santana Rodrigues, Erica Mie Akagi, Nayra Soares do Amaral, Hui Ling, Paloma Monroig, Fernando Augusto Soares, George Adrian Calin,  and Rafael Malagoli Rocha
49217-49231
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gene network analysis reveals a novel 22-gene signature of carbon metabolism in hepatocellular carcinoma

Gene network analysis reveals a novel 22-gene signature of carbon metabolism in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.10249

Jinqiang Zhang, Melody Baddoo, Chang Han, Michael J. Strong, Jennifer Cvitanovic, Krzysztof Moroz, Srikanta Dash, Erik K. Flemington,  and Tong Wu
49232-49245
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A comprehensive characterization of rare mitochondrial DNA variants in neuroblastoma

A comprehensive characterization of rare mitochondrial DNA variants in neuroblastoma

https://doi.org/10.18632/oncotarget.10271

Francesco Maria Calabrese, Rosanna Clima, Piero Pignataro, Vito Alessandro Lasorsa, Michael D. Hogarty, Aurora Castellano, Massimo Conte, Gian Paolo Tonini, Achille Iolascon, Giuseppe Gasparre,  and Mario Capasso
49246-49258
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Concerted action of IFN-α and IFN-λ induces local NK cell immunity and halts cancer growth

Concerted action of IFN-α and IFN-λ induces local NK cell immunity and halts cancer growth

https://doi.org/10.18632/oncotarget.10272

Ahmed Lasfar, Andrew de la Torre, Walid Abushahba, Karine A. Cohen-Solal, Ismael Castaneda, Yao Yuan, Kenneth Reuhl, Andrew Zloza, Elizabeth Raveche, Debra L. Laskin,  and Sergei V. Kotenko
49259-49267
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dynein axonemal heavy chain 8 promotes androgen receptor activity and associates with prostate cancer progression

Dynein axonemal heavy chain 8 promotes androgen receptor activity and associates with prostate cancer progression

https://doi.org/10.18632/oncotarget.10284

Yu Wang, Russell J. Ledet, Keren Imberg-Kazdan, Susan K. Logan,  and Michael J. Garabedian
49268-49280
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Interleukin-13 receptor α2 is associated with poor prognosis in patients with gastric cancer after gastrectomy

Interleukin-13 receptor α2 is associated with poor prognosis in patients with gastric cancer after gastrectomy

https://doi.org/10.18632/oncotarget.10297

Chao Lin, Hao Liu, Heng Zhang, Hongyong He, He Li, Zhenbin Shen, Jin Qin, Xinyu Qin, Jiejie Xu,  and Yihong Sun
49281-49288
Abstract  |  PDF  |  HTML  |  Order a Reprint

Androgen receptor as potential therapeutic target in metastatic endometrial cancer

Androgen receptor as potential therapeutic target in metastatic endometrial cancer

https://doi.org/10.18632/oncotarget.10334

Ingvild Løberg Tangen, Therese Bredholt Onyango, Reidun Kopperud, Anna Berg, Mari K. Halle, Anne M. Øyan, Henrica M.J. Werner, Jone Trovik, Karl Henning Kalland, Helga B. Salvesen,  and Camilla Krakstad
49289-49298
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The contribution of serum hepatitis B virus load in the carcinogenesis and prognosis of hepatocellular carcinoma: evidence from two meta-analyses

The contribution of serum hepatitis B virus load in the carcinogenesis and prognosis of hepatocellular carcinoma: evidence from two meta-analyses

https://doi.org/10.18632/oncotarget.10335

Xueqin Chen, Fan Wu, Yanmei Liu, Jiao Lou, Beibei Zhu, Li Zou, Wei Chen, Jing Gong, Ying Wang,  and Rong Zhong
49299-49309
Abstract  |  PDF  |  HTML  |  Order a Reprint

Desferal regulates hCtr1 and transferrin receptor expression through Sp1 and exhibits synergistic cytotoxicity with platinum drugs in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo

Desferal regulates hCtr1 and transferrin receptor expression through Sp1 and exhibits synergistic cytotoxicity with platinum drugs in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo

https://doi.org/10.18632/oncotarget.10336

Szu-Jung Chen, Ching-Chuan Kuo, Hsin-Yi Pan, Tsui-Chun Tsou, Szu-Ching Yeh,  and Jang-Yang Chang
49310-49321
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients

Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients

https://doi.org/10.18632/oncotarget.10337

A. Marcell Szász, András Lánczky, Ádám Nagy, Susann Förster, Kim Hark, Jeffrey E. Green, Alex Boussioutas, Rita Busuttil, András Szabó,  and Balázs Győrffy
49322-49333
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic significance and function of the vacuolar H+-ATPase subunit V1E1 in esophageal squamous cell carcinoma

Prognostic significance and function of the vacuolar H+-ATPase subunit V1E1 in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.10340

Sung Wook Son, Seok-Hyung Kim, Eun-Yi Moon, Dong-Hoon Kim, Suhkneung Pyo,  and Sung Hee Um
49334-49348
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeted gene silencing of CCL2 inhibits triple negative breast cancer progression by blocking cancer stem cell renewal and M2 macrophage recruitment

Targeted gene silencing of CCL2 inhibits triple negative breast cancer progression by blocking cancer stem cell renewal and M2 macrophage recruitment

https://doi.org/10.18632/oncotarget.9885

Wei Bin Fang, Min Yao, Gage Brummer, Diana Acevedo, Nabil Alhakamy, Cory Berkland,  and Nikki Cheng
49349-49367
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Lin28B promotes Müller glial cell de-differentiation and proliferation in the regenerative rat retinas

Lin28B promotes Müller glial cell de-differentiation and proliferation in the regenerative rat retinas

https://doi.org/10.18632/oncotarget.10343

Zui Tao, Chen Zhao, Qian Jian, Mark Gillies, Haiwei Xu,  and Zheng Qin Yin
49368-49383
Abstract  |  PDF  |  HTML  |  Order a Reprint

PA-MSHA in combination with EGFR tyrosine kinase inhibitor: A new strategy to overcome the drug resistance of non-small cell lung cancer cells

PA-MSHA in combination with EGFR tyrosine kinase inhibitor: A new strategy to overcome the drug resistance of non-small cell lung cancer cells

https://doi.org/10.18632/oncotarget.9891

Xin-min Zhao, Shi-yun Pan, Qi-ling Huang, You-ni Lu, Xiang-hua Wu, Jian-Hua Chang, Zhe-Bin Liu, Xu-Wei Cai, Qi Liu, Jia-lei Wang,  and Xiao-Long Fu
49384-49396
Abstract  |  PDF  |  HTML  |  Order a Reprint

Aldehyde dehydrogenase inhibition combined with phenformin treatment reversed NSCLC through ATP depletion

Aldehyde dehydrogenase inhibition combined with phenformin treatment reversed NSCLC through ATP depletion

https://doi.org/10.18632/oncotarget.10354

Joon Hee Kang, Seon-Hyeong Lee, Jae-Seon Lee, Boas Nam, Tae Wha Seong, Jaekyoung Son, Hyonchol Jang, Kyeong Man Hong, Cheolju Lee,  and Soo-Youl Kim
49397-49410
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sohlh2 suppresses epithelial to mesenchymal transition in breast cancer via downregulation of IL-8

Sohlh2 suppresses epithelial to mesenchymal transition in breast cancer via downregulation of IL-8

https://doi.org/10.18632/oncotarget.10355

Shufang Ji, Wenfang Zhang, Xiaoli Zhang, Chunyan Hao, Aijun Hao, Qing Gao, Hongying Zhang, Jinhao Sun,  and Jing Hao
49411-49424
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cancer-secreted AGR2 induces programmed cell death in normal cells

Cancer-secreted AGR2 induces programmed cell death in normal cells

https://doi.org/10.18632/oncotarget.9921

Elizabeth A. Vitello, Sue-Ing Quek, Heather Kincaid, Thomas Fuchs, Daniel J. Crichton, Pamela Troisch,  and Alvin Y. Liu
49425-49434
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

β-catenin signaling is required for RAS-driven thyroid cancer through PI3K activation

β-catenin signaling is required for RAS-driven thyroid cancer through PI3K activation

https://doi.org/10.18632/oncotarget.10356

Ana Sastre-Perona, Garcilaso Riesco-Eizaguirre, Miguel A. Zaballos,  and Pilar Santisteban
49435-49449
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Disruption of the EZH2/miRNA/β-catenin signaling suppresses aerobic glycolysis in glioma

Disruption of the EZH2/miRNA/β-catenin signaling suppresses aerobic glycolysis in glioma

https://doi.org/10.18632/oncotarget.10370

Yingyi Wang, Min Wang, Wenjin Wei, Dongfeng Han, Xincheng Chen, Qi Hu, Tianfu Yu, Ning Liu, Yongping You,  and Junxia Zhang
49450-49458
Abstract  |  PDF  |  HTML  |  Order a Reprint

CD1d expression on chronic lymphocytic leukemia B cells affects disease progression and induces T cell skewing in CD8 positive and CD4CD8 double negative T cells

CD1d expression on chronic lymphocytic leukemia B cells affects disease progression and induces T cell skewing in CD8 positive and CD4CD8 double negative T cells

https://doi.org/10.18632/oncotarget.10372

Nadja Zaborsky, Franz Josef Gassner, Daniela Asslaber, Petra Reinthaler, Ursula Denk, Sabine Flenady, Josefina Piñón Hofbauer, Barbara Danner, Stefan Rebhandl, Andrea Harrer, Roland Geisberger, Richard Greil,  and Alexander Egle
49459-49469
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Decreased expression of microRNA-320a promotes proliferation and invasion of non-small cell lung cancer cells by increasing VDAC1 expression

Decreased expression of microRNA-320a promotes proliferation and invasion of non-small cell lung cancer cells by increasing VDAC1 expression

https://doi.org/10.18632/oncotarget.9943

Guanxin Zhang, Gengxi Jiang, Chong Wang, Keng Zhong, Jiajun Zhang, Qing Xue, Xin Li, Hai Jin,  and Bailing Li
49470-49480
Abstract  |  PDF  |  HTML  |  Order a Reprint

Accumulation of cytoplasmic Cdk1 is associated with cancer growth and survival rate in epithelial ovarian cancer

Accumulation of cytoplasmic Cdk1 is associated with cancer growth and survival rate in epithelial ovarian cancer

https://doi.org/10.18632/oncotarget.10373

Wookyeom Yang, Hanbyoul Cho, Ha-Yeon Shin, Joon-Yong Chung, Eun Suk Kang, Eun-ju Lee,  and Jae-Hoon Kim
49481-49497
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FNDC3B promotes cell migration and tumor metastasis in hepatocellular carcinoma

FNDC3B promotes cell migration and tumor metastasis in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.10374

Chin-Hui Lin, Yao-Wen Lin, Ying-Chun Chen, Chen-Chung Liao, Yuh-Shan Jou, Ming-Ta Hsu,  and Chian-Feng Chen
49498-49508
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SEP enhanced the antitumor activity of 5-fluorouracil by up-regulating NKG2D/MICA and reversed immune suppression via inhibiting ROS and caspase-3 in mice

SEP enhanced the antitumor activity of 5-fluorouracil by up-regulating NKG2D/MICA and reversed immune suppression via inhibiting ROS and caspase-3 in mice

https://doi.org/10.18632/oncotarget.10375

Mengyun Ke, Hui Wang, Yiran Zhou, Jingwen Li, Yang Liu, Min Zhang, Jie Dou, Tao Xi, Baiyong Shen,  and Changlin Zhou
49509-49526
Abstract  |  PDF  |  HTML  |  Order a Reprint

The anti-cancer activity of the mTORC1/2 dual inhibitor XL388 in preclinical osteosarcoma models

The anti-cancer activity of the mTORC1/2 dual inhibitor XL388 in preclinical osteosarcoma models

https://doi.org/10.18632/oncotarget.10389

Yun-Rong Zhu, Xiao-zhong Zhou, Lun-qing Zhu, Chen Yao, Jian-Feng Fang, Feng Zhou, Xiong-Wei Deng,  and Yun-Qing Zhang
49527-49538
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Smac mimetic induces cell death in a large proportion of primary acute myeloid leukemia samples, which correlates with defined molecular markers

Smac mimetic induces cell death in a large proportion of primary acute myeloid leukemia samples, which correlates with defined molecular markers

https://doi.org/10.18632/oncotarget.10390

Sonja C. Lueck, Annika C. Russ, Ursula Botzenhardt, Richard F. Schlenk, Kerry Zobel, Kurt Deshayes, Domagoj Vucic, Hartmut Döhner, Konstanze Döhner, Simone Fulda,  and Lars Bullinger
49539-49551
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Autocrine glutamatergic transmission for the regulation of embryonal carcinoma stem cells

Autocrine glutamatergic transmission for the regulation of embryonal carcinoma stem cells

https://doi.org/10.18632/oncotarget.9973

Lin Teng, Hui-Min Lei, Fan Sun, Shi-Min An, Ya-Bin Tang, Shuang Meng, Cong-Hui Wang, Ying Shen, Hong-Zhuan Chen,  and Liang Zhu
49552-49564
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical significance and diagnostic value of serum CEA, CA19-9 and CA72-4 in patients with gastric cancer

Clinical significance and diagnostic value of serum CEA, CA19-9 and CA72-4 in patients with gastric cancer

https://doi.org/10.18632/oncotarget.10391

Yao Liang, Wei Wang, Cheng Fang, Seeruttun Sharvesh Raj, Wan-Ming Hu, Qi-Wen Li,  and Zhi-Wei Zhou
49565-49573
Abstract  |  PDF  |  HTML  |  Order a Reprint

Low level phosphorylation of histone H2AX on serine 139 (γH2AX) is not associated with DNA double-strand breaks

Low level phosphorylation of histone H2AX on serine 139 (γH2AX) is not associated with DNA double-strand breaks

https://doi.org/10.18632/oncotarget.10411

Paulina Rybak, Agnieszka Hoang, Lukasz Bujnowicz, Tytus Bernas, Krzysztof Berniak, Mirosław Zarębski, Zbigniew Darzynkiewicz,  and Jerzy Dobrucki
49574-49587
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Triptolide inhibits cell growth and GRP78 protein expression but induces cell apoptosis in original and radioresistant NPC cells

Triptolide inhibits cell growth and GRP78 protein expression but induces cell apoptosis in original and radioresistant NPC cells

https://doi.org/10.18632/oncotarget.10412

Chengmin Li, Bin Zhang, Wuwu Lv, Chen Lai, Zhikang Chen, Ran Wang, Xueying Long,  and Xueping Feng
49588-49596
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922

Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922

https://doi.org/10.18632/oncotarget.10414

Chun Yan Wang, Su Tang Guo, Jia Yu Wang, Xu Guang Yan, Margaret Farrelly, Yuan Yuan Zhang, Fen Liu, Hamed Yari, Ting La, Fu Xi Lei, Lei Jin, Xu Dong Zhang,  and Chen Chen Jiang
49597-49610
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Transcriptome-wide characterization of the endogenous miR-34A-p53 tumor suppressor network

Transcriptome-wide characterization of the endogenous miR-34A-p53 tumor suppressor network

https://doi.org/10.18632/oncotarget.10417

Nardin Samuel, Gavin Wilson, Badr Id Said, Anna Pan, Genevieve Deblois, Nicholas W. Fischer, Roumiana Alexandrova, Guillermo Casallo, Tara Paton, Mathieu Lupien, Jean Gariepy, Daniele Merico, Thomas J. Hudson,  and David Malkin
49611-49622
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

In-depth proteomic profiling of the uveal melanoma secretome

In-depth proteomic profiling of the uveal melanoma secretome

https://doi.org/10.18632/oncotarget.10418

Martina Angi, Helen Kalirai, Samuel Prendergast, Deborah Simpson, Dean E. Hammond, Michele C. Madigan, Robert J. Beynon,  and Sarah E. Coupland
49623-49635
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metformin as a new anti-cancer drug in adrenocortical carcinoma

Metformin as a new anti-cancer drug in adrenocortical carcinoma

https://doi.org/10.18632/oncotarget.10421

Giada Poli, Giulia Cantini, Roberta Armignacco, Rossella Fucci, Raffaella Santi, Letizia Canu, Gabriella Nesi, Massimo Mannelli,  and Michaela Luconi
49636-49648
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeting of RET oncogene by naphthalene diimide-mediated gene promoter G-quadruplex stabilization exerts anti-tumor activity in oncogene-addicted human medullary thyroid cancer

Targeting of RET oncogene by naphthalene diimide-mediated gene promoter G-quadruplex stabilization exerts anti-tumor activity in oncogene-addicted human medullary thyroid cancer

https://doi.org/10.18632/oncotarget.10105

Alessia Lopergolo, Rosalba Perrone, Monica Tortoreto, Filippo Doria, Giovanni L. Beretta, Valentina Zuco, Mauro Freccero, Maria Grazia Borrello, Cinzia Lanzi, Sara N. Richter, Nadia Zaffaroni,  and Marco Folini
49649-49663
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

P2X7 targeting inhibits growth of human mesothelioma

P2X7 targeting inhibits growth of human mesothelioma

https://doi.org/10.18632/oncotarget.10430

Francesca Amoroso, Erica Salaro, Simonetta Falzoni, Paola Chiozzi, Anna Lisa Giuliani, Giorgio Cavallesco, Pio Maniscalco, Andrea Puozzo, Ilaria Bononi, Fernanda Martini, Mauro Tognon,  and Francesco Di Virgilio
49664-49676
Abstract  |  PDF  |  HTML  |  Order a Reprint

The “melanoma-enriched” microRNA miR-4731-5p acts as a tumour suppressor

The “melanoma-enriched” microRNA miR-4731-5p acts as a tumour suppressor

https://doi.org/10.18632/oncotarget.10109

Mitchell S. Stark, Lisa N. Tom, Glen M. Boyle, Vanessa F. Bonazzi, Peter H. Soyer, Adrian C. Herington, Pamela M. Pollock,  and Nicholas K. Hayward
49677-49687
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long non-coding RNA-MIAT promotes neurovascular remodeling in the eye and brain

Long non-coding RNA-MIAT promotes neurovascular remodeling in the eye and brain

https://doi.org/10.18632/oncotarget.10434

Qin Jiang, Kun Shan, Xiao Qun-Wang, Rong-Mei Zhou, Hong Yang, Chang Liu, Yu-Jie Li, Jin Yao, Xiu-Miao Li, Yi Shen, Hong Cheng, Jun Yuan, Yang-Yang Zhang,  and Biao Yan
49688-49698
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dasatinib-loaded albumin nanoparticles possess diminished endothelial cell barrier disruption and retain potent anti-leukemia cell activity

Dasatinib-loaded albumin nanoparticles possess diminished endothelial cell barrier disruption and retain potent anti-leukemia cell activity

https://doi.org/10.18632/oncotarget.10435

Chunling Dong, Bo Li, Zhenyu Li, Sreerama Shetty,  and Jian Fu
49699-49709
Abstract  |  PDF  |  HTML  |  Order a Reprint

Increasing sensitivity to DNA damage is a potential driver for human ovarian cancer

Increasing sensitivity to DNA damage is a potential driver for human ovarian cancer

https://doi.org/10.18632/oncotarget.10436

Yimei Jin, Xin Xu, Xuemeng Wang, Henry Kuang, Michael Osterman, Shi Feng, Deqiang Han, Yu Wu, Mo Li,  and Hongyan Guo
49710-49721
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High CRLF2 expression associates with IKZF1 dysfunction in adult acute lymphoblastic leukemia without CRLF2 rearrangement

High CRLF2 expression associates with IKZF1 dysfunction in adult acute lymphoblastic leukemia without CRLF2 rearrangement

https://doi.org/10.18632/oncotarget.10437

Zheng Ge, Yan Gu, Gang Zhao, Jianyong Li, Baoan Chen, Qi Han, Xing Guo, Juan Liu, Hui Li, Michael D. Yu, Justin Olson, Sadie Steffens, Kimberly J. Payne, Chunhua Song,  and Sinisa Dovat
49722-49732
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting FGFR1 to suppress leukemogenesis in syndromic and de novo AML in murine models

Targeting FGFR1 to suppress leukemogenesis in syndromic and de novo AML in murine models

https://doi.org/10.18632/oncotarget.10438

Qing Wu, Aaron Bhole, Haiyan Qin, Judith Karp, Sami Malek, John K Cowell,  and Mingqiang Ren
49733-49742
Abstract  |  PDF  |  HTML  |  Order a Reprint

Elevated expression of the IGF2 mRNA binding protein 2 (IGF2BP2/IMP2) is linked to short survival and metastasis in esophageal adenocarcinoma

Elevated expression of the IGF2 mRNA binding protein 2 (IGF2BP2/IMP2) is linked to short survival and metastasis in esophageal adenocarcinoma

https://doi.org/10.18632/oncotarget.10439

Ahmad Barghash, Nicole Golob-Schwarzl, Volkhard Helms, Johannes Haybaeck,  and Sonja M. Kessler
49743-49750
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Novel ERα positive breast cancer model with estrogen independent growth in the bone microenvironment

Novel ERα positive breast cancer model with estrogen independent growth in the bone microenvironment

https://doi.org/10.18632/oncotarget.10443

Aude-Hélène Capietto, Szeman Ruby Chan, Biancamaria Ricci, Julie A. Allen, Xinming Su, Deborah V Novack, Robert D. Schreiber,  and Roberta Faccio
49751-49764
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prediction of early hepatocellular carcinoma recurrence using germinal center kinase-like kinase

Prediction of early hepatocellular carcinoma recurrence using germinal center kinase-like kinase

https://doi.org/10.18632/oncotarget.10176

Cheng-Hsun Ho, Huai-Chia Chuang, I-Chin Wu, Hung-Wen Tsai, Yih-Jyh Lin, Hung-Yu Sun, Kung-Chia Young, Yen-Cheng Chiu, Pin-Nan Cheng, Wen-Chun Liu, Tse-Hua Tan,  and Ting-Tsung Chang
49765-49776
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel isoflavone, ME-344, targets the cytoskeleton in acute myeloid leukemia

A novel isoflavone, ME-344, targets the cytoskeleton in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.10446

Danny V. Jeyaraju, Rose Hurren, Xiaoming Wang, Neil MacLean, Marcela Gronda, Aisha Shamas-Din, Mark D. Minden, Guri Giaever,  and Aaron D. Schimmer
49777-49785
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FLT3 is implicated in cytarabine transport by human equilibrative nucleoside transporter 1 in pediatric acute leukemia

FLT3 is implicated in cytarabine transport by human equilibrative nucleoside transporter 1 in pediatric acute leukemia

https://doi.org/10.18632/oncotarget.10448

Albert Català, Marçal Pastor-Anglada, Liska Caviedes-Cárdenas, Roberta Malatesta, Susana Rives, Nerea Vega-García, Mireia Camós,  and Paula Fernández-Calotti
49786-49799
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling

Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling

https://doi.org/10.18632/oncotarget.10452

Jaclyn Quin, Keefe T. Chan, Jennifer R. Devlin, Donald P. Cameron, Jeannine Diesch, Carleen Cullinane, Jessica Ahern, Amit Khot, Nadine Hein, Amee J. George, Katherine M Hannan, Gretchen Poortinga, Karen E. Sheppard, Kum Kum Khanna, Ricky W. Johnstone, Denis Drygin, Grant A. McArthur, Richard B. Pearson, Elaine Sanij,  and Ross D. Hannan
49800-49818
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Connexin43 recruits PTEN and Csk to inhibit c-Src activity in glioma cells and astrocytes

Connexin43 recruits PTEN and Csk to inhibit c-Src activity in glioma cells and astrocytes

https://doi.org/10.18632/oncotarget.10454

Ana González-Sánchez, Myriam Jaraíz-Rodríguez, Marta Domínguez-Prieto, Sandra Herrero-González, José M. Medina,  and Arantxa Tabernero
49819-49833
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High expression of WISP1 in colon cancer is associated with apoptosis, invasion and poor prognosis

High expression of WISP1 in colon cancer is associated with apoptosis, invasion and poor prognosis

https://doi.org/10.18632/oncotarget.10486

Jianghong Wu, Ziwen Long, Hong Cai, Chunyan Du, Xiaowen Liu, Shengjia Yu,  and Yanong Wang
49834-49847
Abstract  |  PDF  |  HTML  |  Order a Reprint

Histone deacetylase inhibitors regulate P-gp expression in colorectal cancer via transcriptional activation and mRNA stabilization

Histone deacetylase inhibitors regulate P-gp expression in colorectal cancer via transcriptional activation and mRNA stabilization

https://doi.org/10.18632/oncotarget.10488

Hao Wang, Cheng Huang, Liang Zhao, Huan Zhang, Jing Mo Yang, Peng Luo, Bing-Xiang Zhan, Qing Pan, Jun Li,  and Bao-Long Wang
49848-49858
Abstract  |  PDF  |  HTML  |  Order a Reprint

The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer

The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer

https://doi.org/10.18632/oncotarget.10489

Umar Raza, Özge Saatci, Stefan Uhlmann, Suhail A Ansari, Erol Eyüpoğlu, Emre Yurdusev, Merve Mutlu, Pelin Gülizar Ersan, Mustafa Kadri Altundağ, Jitao David Zhang, Hayriye Tatlı Doğan, Gülnur Güler,  and Özgür Şahin
49859-49877
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinicopathological and prognostic significance of platelet to lymphocyte ratio in patients with gastric cancer

Clinicopathological and prognostic significance of platelet to lymphocyte ratio in patients with gastric cancer

https://doi.org/10.18632/oncotarget.10490

Xiaobin Gu, Xian-Shu Gao, Ming Cui, Mu Xie, Chuan Peng, Yun Bai, Wei Guo, Linjun Han, Xiaodong Gu,  and Wei Xiong
49878-49887
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting the WEE1 kinase as a molecular targeted therapy for gastric cancer

Targeting the WEE1 kinase as a molecular targeted therapy for gastric cancer

https://doi.org/10.18632/oncotarget.10231

Hye-Young Kim, Yunhee Cho, HyeokGu Kang, Ye-Seal Yim, Seok-Jun Kim, Jaewhan Song,  and Kyung-Hee Chun
49902-49916
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comprehensive analysis of lncRNAs microarray profile and mRNA–lncRNA co-expression in oncogenic HPV-positive cervical cancer cell lines

Comprehensive analysis of lncRNAs microarray profile and mRNA–lncRNA co-expression in oncogenic HPV-positive cervical cancer cell lines

https://doi.org/10.18632/oncotarget.10232

LingYun Yang, Ke Yi, HongJing Wang, YiQi Zhao,  and MingRong Xi
49917-49929
Abstract  |  PDF  |  HTML  |  Order a Reprint

Thyroid functional parameters and correlative autoantibodies as prognostic factors for differentiated thyroid cancers

Thyroid functional parameters and correlative autoantibodies as prognostic factors for differentiated thyroid cancers

https://doi.org/10.18632/oncotarget.10236

Chao Li, Wenbin Yu, Jinchuan Fan, Guojun Li, Xiaofeng Tao, Yun Feng,  and Ronghao Sun
49930-49938
Abstract  |  PDF  |  HTML  |  Order a Reprint

What might explain deprivation-specific differences in the excess hazard of breast cancer death amongst screen-detected women? Analysis of patients diagnosed in the West Midlands region of England from 1989 to 2011

What might explain deprivation-specific differences in the excess hazard of breast cancer death amongst screen-detected women? Analysis of patients diagnosed in the West Midlands region of England from 1989 to 2011

https://doi.org/10.18632/oncotarget.10255

Melanie Morris, Laura M. Woods,  and Bernard Rachet
49939-49947
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long non-coding RNA BC087858 induces non-T790M mutation acquired resistance to EGFR-TKIs by activating PI3K/AKT and MEK/ERK pathways and EMT in non-small-cell lung cancer

Long non-coding RNA BC087858 induces non-T790M mutation acquired resistance to EGFR-TKIs by activating PI3K/AKT and MEK/ERK pathways and EMT in non-small-cell lung cancer

https://doi.org/10.18632/oncotarget.10521

Hui Pan, Tao Jiang, Ningning Cheng, Qi Wang, Shengxiang Ren, Xuefei Li, Chao Zhao, Limin Zhang, Weijing Cai,  and Caicun Zhou
49948-49960
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Docosahexaenoic acid suppresses breast cancer cell metastasis by targeting matrix-metalloproteinases

Docosahexaenoic acid suppresses breast cancer cell metastasis by targeting matrix-metalloproteinases

https://doi.org/10.18632/oncotarget.10266

Eun-Jin Yun, Kyung-Sub Song, Soyeon Shin, Soyeon Kim, Jun-Young Heo, Gi-Ryang Kweon, Tong Wu, Jong-Il Park,  and Kyu Lim
49961-49971
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Antibody neutralization of cell-surface gC1qR/HABP1/SF2-p32 prevents lamellipodia formation and tumorigenesis

Antibody neutralization of cell-surface gC1qR/HABP1/SF2-p32 prevents lamellipodia formation and tumorigenesis

https://doi.org/10.18632/oncotarget.10267

Beom-Chan Kim, Hyun-Jung Hwang, Hyoung-Tae An, Hyun Lee, Jun-Sub Park, Jin Hong, Jesang Ko, Chungho Kim, Jae-Seon Lee,  and Young-Gyu Ko
49972-49985
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Transcriptomic reappraisal identifies MGLL overexpression as an unfavorable prognosticator in primary gastrointestinal stromal tumors

Transcriptomic reappraisal identifies MGLL overexpression as an unfavorable prognosticator in primary gastrointestinal stromal tumors

https://doi.org/10.18632/oncotarget.10304

Chien-Feng Li, I-Chieh Chuang, Ting-Ting Liu, Ko-Chin Chen, Yen-Yang Chen, Fu-Min Fang, Shau-Hsuan Li, Tzu-Ju Chen, Shih-Chen Yu, Jui Lan,  and Hsuan-Ying Huang
49986-49997
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

AHNAK enables mammary carcinoma cells to produce extracellular vesicles that increase neighboring fibroblast cell motility

AHNAK enables mammary carcinoma cells to produce extracellular vesicles that increase neighboring fibroblast cell motility

https://doi.org/10.18632/oncotarget.10307

Thaiomara A. Silva, Basílio Smuczek, Iuri C. Valadão, Luciana M. Dzik, Rebeca P. Iglesia, Mário C. Cruz, André Zelanis, Adriane S. de Siqueira, Solange M.T. Serrano, Gary S. Goldberg, Ruy G. Jaeger,  and Vanessa M. Freitas
49998-50016
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Increased expression of MUC3A is associated with poor prognosis in localized clear-cell renal cell carcinoma

Increased expression of MUC3A is associated with poor prognosis in localized clear-cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.10312

Tian Niu, Yidong Liu, Yuan Zhang, Qiang Fu, Zheng Liu, Zewei Wang, Hangcheng Fu, Jiejie Xu,  and Kun Liu
50017-50026
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting synthetic lethality between the SRC kinase and the EPHB6 receptor may benefit cancer treatment

Targeting synthetic lethality between the SRC kinase and the EPHB6 receptor may benefit cancer treatment

https://doi.org/10.18632/oncotarget.10569

James M. Paul, Behzad Toosi, Frederick S. Vizeacoumar, Kalpana Kalyanasundaram Bhanumathy, Yue Li, Courtney Gerger, Amr El Zawily, Tanya Freywald, Deborah H. Anderson, Darrell Mousseau, Rani Kanthan, Zhaolei Zhang, Franco J. Vizeacoumar,  and Andrew Freywald
50027-50042
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress

Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress

https://doi.org/10.18632/oncotarget.10571

Hiroshi Saijo, Yoshihiko Hirohashi, Toshihiko Torigoe, Ryota Horibe, Akari Takaya, Aiko Murai, Terufumi Kubo, Toshimitsu Kajiwara, Tsutomu Tanaka, Yosuke Shionoya, Eri Yamamoto, Reo Maruyama, Munehide Nakatsugawa, Takayuki Kanaseki, Tomohide Tsukahara, Yasuaki Tamura, Yasushi Sasaki, Takashi Tokino, Hiromu Suzuki, Toru Kondo, Hiroki Takahashi,  and Noriyuki Sato
50043-50056
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling

Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling

https://doi.org/10.18632/oncotarget.10315

Bin Xiao, Daxiang Chen, Shuhong Luo, Wenbo Hao, Fangyan Jing, Tiancai Liu, Suihai Wang, Yan Geng, Linhai Li, Weiwen Xu, Yajie Zhang, Xiaoqing Liao, Daming Zuo, Yingsong Wu, Ming Li,  and Qiang Ma
50057-50073
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ASC contributes to metastasis of oral cavity squamous cell carcinoma

ASC contributes to metastasis of oral cavity squamous cell carcinoma

https://doi.org/10.18632/oncotarget.10317

Chi-Sheng Wu, Kai-Ping Chang, Chun-Nan OuYang, Huang-Kai Kao, Chuen Hsueh, Lih-Chyang Chen, Hsiao-Yun Cheng, Ying Liang, Willisa Liou, Chih-lung Liang,  and Yu-Sun Chang
50074-50085
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Exosomes from human colorectal cancer induce a tumor-like behavior in colonic mesenchymal stromal cells

Exosomes from human colorectal cancer induce a tumor-like behavior in colonic mesenchymal stromal cells

https://doi.org/10.18632/oncotarget.10574

Luana Lugini, Mauro Valtieri, Cristina Federici, Serena Cecchetti, Stefania Meschini, Maria Condello, Michele Signore,  and Stefano Fais
50086-50098
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Class A1 scavenger receptor modulates glioma progression by regulating M2-like tumor-associated macrophage polarization

Class A1 scavenger receptor modulates glioma progression by regulating M2-like tumor-associated macrophage polarization

https://doi.org/10.18632/oncotarget.10318

Hanwen Zhang, Wenbin Zhang, Xuan Sun, Ruoyu Dang, Rongmei Zhou, Hui Bai, Jingjing Ben, Xudong Zhu, Yan Zhang, Qing Yang, Yong Xu,  and Qi Chen
50099-50116
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sirtuin 3 enhanced drug sensitivity of human hepatoma cells through glutathione S-transferase pi 1/JNK signaling pathway

Sirtuin 3 enhanced drug sensitivity of human hepatoma cells through glutathione S-transferase pi 1/JNK signaling pathway

https://doi.org/10.18632/oncotarget.10319

Na-Na Tao, Hong-Zhong Zhou, Hua Tang, Xue-Fei Cai, Wen-Lu Zhang, Ji-Hua Ren, Li Zhou, Xiang Chen, Ke Chen, Wan-Yu Li, Bo Liu, Qiu-Xia Yang, Sheng-Tao Cheng, Li-Xia Huang, Ai-Long Huang,  and Juan Chen
50117-50130
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inflammatory related gene IKKα, IKKβ, IKKγ cooperates to determine liver cancer stem cells progression by altering telomere via heterochromatin protein 1-HOTAIR axis

Inflammatory related gene IKKα, IKKβ, IKKγ cooperates to determine liver cancer stem cells progression by altering telomere via heterochromatin protein 1-HOTAIR axis

https://doi.org/10.18632/oncotarget.10321

Jiahui An, Mengying Wu, Xiaoru Xin, Zhuojia Lin, Xiaonan Li, Qidi Zheng, Xin Gui, Tianming Li, Hu Pu, Haiyan Li,  and Dongdong Lu
50131-50149
Abstract  |  PDF  |  HTML  |  Order a Reprint

Evaluation of the risk of lymphomagenesis in xenografts by the PCR-based detection of EBV BamHI W region in patient cancer specimens

Evaluation of the risk of lymphomagenesis in xenografts by the PCR-based detection of EBV BamHI W region in patient cancer specimens

https://doi.org/10.18632/oncotarget.10322

Junko Mukohyama, Dai Iwakiri, Yoh Zen, Toru Mukohara, Hironobu Minami, Yoshihiro Kakeji,  and Yohei Shimono
50150-50160
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Acquired nintedanib resistance in FGFR1-driven small cell lung cancer: role of endothelin-A receptor-activated ABCB1 expression

Acquired nintedanib resistance in FGFR1-driven small cell lung cancer: role of endothelin-A receptor-activated ABCB1 expression

https://doi.org/10.18632/oncotarget.10324

Bernhard Englinger, Daniela Lötsch, Christine Pirker, Thomas Mohr, Sushilla van Schoonhoven, Bernd Boidol, Charles-Hugues Lardeau, Melanie Spitzwieser, Pál Szabó, Petra Heffeter, Irene Lang, Margit Cichna-Markl, Bettina Grasl-Kraupp, Brigitte Marian, Michael Grusch, Stefan Kubicek, Gergely Szakács,  and Walter Berger
50161-50179
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Capsaicin triggers autophagic cell survival which drives epithelial mesenchymal transition and chemoresistance in bladder cancer cells in an Hedgehog-dependent manner

Capsaicin triggers autophagic cell survival which drives epithelial mesenchymal transition and chemoresistance in bladder cancer cells in an Hedgehog-dependent manner

https://doi.org/10.18632/oncotarget.10326

Consuelo Amantini, Maria Beatrice Morelli, Massimo Nabissi, Claudio Cardinali, Matteo Santoni, Angela Gismondi,  and Giorgio Santoni
50180-50194
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SIRT1 and LSD1 competitively regulate KU70 functions in DNA repair and mutation acquisition in cancer cells

SIRT1 and LSD1 competitively regulate KU70 functions in DNA repair and mutation acquisition in cancer cells

https://doi.org/10.18632/oncotarget.10328

Mendel Roth, Zhiqiang Wang,  and Wen Yong Chen
50195-50214
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mitotic p21Cip1/CDKN1A is regulated by cyclin-dependent kinase 1 phosphorylation

Mitotic p21Cip1/CDKN1A is regulated by cyclin-dependent kinase 1 phosphorylation

https://doi.org/10.18632/oncotarget.10330

Nina-Naomi Kreis, Alexandra Friemel, Brigitte Zimmer, Susanne Roth, Michael A. Rieger, Udo Rolle, Frank Louwen,  and Juping Yuan
50215-50228
Abstract  |  PDF  |  HTML  |  Order a Reprint

miR-29c contribute to glioma cells temozolomide sensitivity by targeting O6-methylguanine-DNA methyltransferases indirectly

miR-29c contribute to glioma cells temozolomide sensitivity by targeting O6-methylguanine-DNA methyltransferases indirectly

https://doi.org/10.18632/oncotarget.10357

Songhua Xiao, Zhen Yang, Xingsheng Qiu, Ruiyan Lv, Jun Liu, Ming Wu, Yiwei Liao,  and Qing Liu
50229-50238
Abstract  |  PDF  |  HTML  |  Order a Reprint

High expression of MnSOD promotes survival of circulating breast cancer cells and increases their resistance to doxorubicin

High expression of MnSOD promotes survival of circulating breast cancer cells and increases their resistance to doxorubicin

https://doi.org/10.18632/oncotarget.10360

Afu Fu, Shijun Ma, Na Wei, Blanche Xiao Xuan Tan, Ern Yu Tan,  and Kathy Qian Luo
50239-50257
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Compounds from the marine sponge Cribrochalina vasculum offer a way to target IGF-1R mediated signaling in tumor cells

Compounds from the marine sponge Cribrochalina vasculum offer a way to target IGF-1R mediated signaling in tumor cells

https://doi.org/10.18632/oncotarget.10361

Ana Zovko, Metka Novak, Petra Hååg, Dimitry Kovalerchick, Teresa Holmlund, Katarina Färnegårdh, Micha Ilan, Shmuel Carmeli, Rolf Lewensohn,  and Kristina Viktorsson
50258-50276
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sunitinib enhances the antitumor responses of agonistic CD40-antibody by reducing MDSCs and synergistically improving endothelial activation and T-cell recruitment

Sunitinib enhances the antitumor responses of agonistic CD40-antibody by reducing MDSCs and synergistically improving endothelial activation and T-cell recruitment

https://doi.org/10.18632/oncotarget.10364

Luuk van Hooren, Maria Georganaki, Hua Huang, Sara M. Mangsbo,  and Anna Dimberg
50277-50289
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Antitumor activity of the aurora a selective kinase inhibitor, alisertib, against preclinical models of colorectal cancer

Antitumor activity of the aurora a selective kinase inhibitor, alisertib, against preclinical models of colorectal cancer

https://doi.org/10.18632/oncotarget.10366

Todd M. Pitts, Erica L. Bradshaw-Pierce, Stacey M. Bagby, Stephanie L. Hyatt, Heather M. Selby, Anna Spreafico, John J. Tentler, Kelly McPhillips, Peter J. Klauck, Anna Capasso, Jennifer R. Diamond, Lindsey S. Davis, Aik Choon Tan, John J. Arcaroli, Alicia Purkey, Wells A. Messersmith, Jeffery A. Ecsedy,  and Gail S. Eckhardt
50290-50301
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Halofuginone and artemisinin synergistically arrest cancer cells at the G1/G0 phase by upregulating p21Cip1 and p27Kip1

Halofuginone and artemisinin synergistically arrest cancer cells at the G1/G0 phase by upregulating p21Cip1 and p27Kip1

https://doi.org/10.18632/oncotarget.10367

Guoqing Chen, Ruihong Gong, Xianli Shi, Dajian Yang, Ge Zhang, Aiping Lu, Jianbo Yue,  and Zhaoxiang Bian
50302-50314
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TMPRSS4 induces invasion and proliferation of prostate cancer cells through induction of Slug and cyclin D1

TMPRSS4 induces invasion and proliferation of prostate cancer cells through induction of Slug and cyclin D1

https://doi.org/10.18632/oncotarget.10382

Yunhee Lee, Dongjoon Ko, Hye-Jin Min, Sol Bi Kim, Hye-Mi Ahn, Younghoon Lee,  and Semi Kim
50315-50332
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

5-FU targets rpL3 to induce mitochondrial apoptosis via cystathionine-β-synthase in colon cancer cells lacking p53

5-FU targets rpL3 to induce mitochondrial apoptosis via cystathionine-β-synthase in colon cancer cells lacking p53

https://doi.org/10.18632/oncotarget.10385

Valentina Pagliara, Assunta Saide, Emma Mitidieri, Roberta d’Emmanuele di Villa Bianca, Raffaella Sorrentino, Giulia Russo,  and Annapina Russo
50333-50348
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TrkB-containing exosomes promote the transfer of glioblastoma aggressiveness to YKL-40-inactivated glioblastoma cells

TrkB-containing exosomes promote the transfer of glioblastoma aggressiveness to YKL-40-inactivated glioblastoma cells

https://doi.org/10.18632/oncotarget.10387

Sandra Pinet, Barbara Bessette, Nicolas Vedrenne, Aurélie Lacroix, Laurence Richard, Marie-Odile Jauberteau, Serge Battu,  and Fabrice Lalloué
50349-50364
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Microvesicle removal of anticancer drugs contributes to drug resistance in human pancreatic cancer cells

Microvesicle removal of anticancer drugs contributes to drug resistance in human pancreatic cancer cells

https://doi.org/10.18632/oncotarget.10395

Vandhana Muralidharan-Chari, Hamed Gilzad Kohan, Alexandros G. Asimakopoulos, Thangirala Sudha, Stewart Sell, Kurunthachalam Kannan, Mehdi Boroujerdi, Paul J. Davis,  and Shaker A. Mousa
50365-50379
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Optogenetic regulation of site-specific subtelomeric DNA methylation

Optogenetic regulation of site-specific subtelomeric DNA methylation

https://doi.org/10.18632/oncotarget.10394

Samrat Roy Choudhury, Yi Cui, Anoop Narayanan, David P. Gilley, Nazmul Huda, Chiao-Ling Lo, Feng C. Zhou, Dinesh Yernool,  and Joseph Irudayaraj
50380-50391
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel pathogenic large germline deletion in adenomatous polyposis coli gene in a Chinese family with familial adenomatous polyposis

A novel pathogenic large germline deletion in adenomatous polyposis coli gene in a Chinese family with familial adenomatous polyposis

https://doi.org/10.18632/oncotarget.10408

Zhao Zhang, Shengran Liang, Hui Huang, Dan Wang, Xipeng Zhang, Jing Wu, Huishuang Chen, Yanyan Wang, Tingting Rong, Yulin Zhou,  and Santasree Banerjee
50392-50400
Abstract  |  PDF  |  HTML  |  Order a Reprint

Inhibition of canonical WNT/β-catenin signaling is involved in leflunomide (LEF)-mediated cytotoxic effects on renal carcinoma cells

Inhibition of canonical WNT/β-catenin signaling is involved in leflunomide (LEF)-mediated cytotoxic effects on renal carcinoma cells

https://doi.org/10.18632/oncotarget.10409

Yicheng Chen, Qiaoli Huang, Hua Zhou, Yueping Wang, Xian Hu,  and Tao Li
50401-50416
Abstract  |  PDF  |  HTML  |  Order a Reprint

HMGB1 overexpression as a prognostic factor for survival in cancer: a meta-analysis and systematic review

HMGB1 overexpression as a prognostic factor for survival in cancer: a meta-analysis and systematic review

https://doi.org/10.18632/oncotarget.10413

Tengyun Wu, Wei Zhang, Geliang Yang, Huijun Li, Qi Chen, Ruixiang Song,  and Lin Zhao
50417-50427
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long non-coding RNAs: novel prognostic biomarkers for liver metastases in patients with early stage colorectal cancer

Long non-coding RNAs: novel prognostic biomarkers for liver metastases in patients with early stage colorectal cancer

https://doi.org/10.18632/oncotarget.10416

Hui Kong, Ying Wu, Mengou Zhu, Changwen Zhai, Jing Qian, Xue Gao, Shuyang Wang, Yingyong Hou, Shaohua Lu,  and Hongguang Zhu
50428-50436
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Notch pathway activation is essential for maintenance of stem-like cells in early tongue cancer

Notch pathway activation is essential for maintenance of stem-like cells in early tongue cancer

https://doi.org/10.18632/oncotarget.10419

Pawan Upadhyay, Sudhir Nair, Ekjot Kaur, Jyotirmoi Aich, Prachi Dani, Vidyalakshmi Sethunath, Nilesh Gardi, Pratik Chandrani, Mukul Godbole, Kavita Sonawane, Ratnam Prasad, Sadhana Kannan, Beamon Agarwal, Shubhada Kane, Sudeep Gupta, Shilpee Dutt,  and Amit Dutt
50437-50449
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High intensity focused ultrasound inhibits melanoma cell migration and metastasis through attenuating microRNA-21-mediated PTEN suppression

High intensity focused ultrasound inhibits melanoma cell migration and metastasis through attenuating microRNA-21-mediated PTEN suppression

https://doi.org/10.18632/oncotarget.10433

Huan Li, Shi-mei Yuan, Min Yang, He Zha, Xue-ru Li, Hui Sun, Liang Duan, Yue Gu, Ai-fang Li, Ya-guang Weng, Jin-yong Luo, Tong-chuan He, Yan Wang, Chong-yan Li, Fa-qi Li, Zhi-biao Wang,  and Lan Zhou
50450-50460
Abstract  |  PDF  |  HTML  |  Order a Reprint

Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases

Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases

https://doi.org/10.18632/oncotarget.10459

Ann-Katrin Sommer, Adam Hermawan, Frauke Martina Mickler, Bojan Ljepoja, Pjotr Knyazev, Christoph Bräuchle, Axel Ullrich, Ernst Wagner,  and Andreas Roidl
50461-50476
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comprehensive profiling and quantitation of oncogenic mutations in non small-cell lung carcinoma using single molecule amplification and re-sequencing technology

Comprehensive profiling and quantitation of oncogenic mutations in non small-cell lung carcinoma using single molecule amplification and re-sequencing technology

https://doi.org/10.18632/oncotarget.10464

Shirong Zhang, Bing Xia, Hong Jiang, Limin Wang, Rujun Xu, Yanbin Shi, Jianguang Zhang, Mengnan Xu, David S. Cram,  and Shenglin Ma
50477-50489
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Myotubularin-related protein 7 inhibits insulin signaling in colorectal cancer

Myotubularin-related protein 7 inhibits insulin signaling in colorectal cancer

https://doi.org/10.18632/oncotarget.10466

Philip Weidner, Michaela Söhn, Tobias Gutting, Teresa Friedrich, Timo Gaiser, Julia Magdeburg, Peter Kienle, Hermelindis Ruh, Carsten Hopf, Hans-Michael Behrens, Christoph Röcken, Tamar Hanoch, Rony Seger, Matthias P.A. Ebert,  and Elke Burgermeister
50490-50506
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Snail promotes resistance to enzalutamide through regulation of androgen receptor activity in prostate cancer

Snail promotes resistance to enzalutamide through regulation of androgen receptor activity in prostate cancer

https://doi.org/10.18632/oncotarget.10476

Kathryn E. Ware, Jason A. Somarelli, Daneen Schaeffer, Jing Li, Tian Zhang, Sally Park, Steven R. Patierno, Jennifer Freedman, Wen-Chi Foo, Mariano A. Garcia-Blanco,  and Andrew J. Armstrong
50507-50521
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SUMOylation of PES1 upregulates its stability and function via inhibiting its ubiquitination

SUMOylation of PES1 upregulates its stability and function via inhibiting its ubiquitination

https://doi.org/10.18632/oncotarget.10494

Shujing Li, Miao Wang, Xinjian Qu, Zhaowei Xu, Yangyang Yang, Qiming Su,  and Huijian Wu
50522-50534
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Branched multipeptide immunotherapy for glioblastoma using human leukocyte antigen-A*0201-restricted cytotoxic T-lymphocyte epitopes from ERBB2, BIRC5 and CD99

Branched multipeptide immunotherapy for glioblastoma using human leukocyte antigen-A*0201-restricted cytotoxic T-lymphocyte epitopes from ERBB2, BIRC5 and CD99

https://doi.org/10.18632/oncotarget.10495

Young-Hee Kim, Thi-Anh-Thuy Tran, Hyun-Ju Lee, Sook-In Jung, Je-Jung Lee, Wool-Youl Jang, Kyung-Sub Moon, In-Young Kim, Shin Jung,  and Tae- Young Jung
50535-50547
Abstract  |  PDF  |  HTML  |  Order a Reprint

Stress-induced phosphoprotein-1 maintains the stability of JAK2 in cancer cells

Stress-induced phosphoprotein-1 maintains the stability of JAK2 in cancer cells

https://doi.org/10.18632/oncotarget.10500

Chia-Lung Tsai, Angel Chao, Shih-Ming Jung, Chi-Neu Tsai, Chiao-Yun Lin, Shun-Hua Chen, Shih-Che Sue, Tzu-Hao Wang, Hsin-Shih Wang,  and Chyong- Huey Lai
50548-50563
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TREM-1 expression in craniopharyngioma and Rathke’s cleft cyst: its possible implication for controversial pathology

TREM-1 expression in craniopharyngioma and Rathke’s cleft cyst: its possible implication for controversial pathology

https://doi.org/10.18632/oncotarget.10501

Yi Liu, Chao-hu Wang, Dan-ling Li, Shi-chao Zhang, Yu-ping Peng, Jun-xiang Peng, Ye Song, Song-tao Qi,  and Jun Pan
50564-50574
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cetuximab response in CRC patient-derived xenografts seems predicted by an expression based RAS pathway signature

Cetuximab response in CRC patient-derived xenografts seems predicted by an expression based RAS pathway signature

https://doi.org/10.18632/oncotarget.10499

Sheng Guo, Dawei Chen, Xuesong Huang, Jie Cai, Jean-Pierre Wery,  and Qi-Xiang Li
50575-50581
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Panels of tumor-derived RNA markers in peripheral blood of patients with non-small cell lung cancer: their dependence on age, gender and clinical stages

Panels of tumor-derived RNA markers in peripheral blood of patients with non-small cell lung cancer: their dependence on age, gender and clinical stages

https://doi.org/10.18632/oncotarget.10558

Chih-Feng Chian, Yi-Ting Hwang, Harn-Jing Terng, Shih-Chun Lee, Tsui-Yi Chao, Hung Chang, Ching-Liang Ho, Yi-Ying Wu,  and Wann-Cherng Perng
50582-50595
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cambogin exerts anti-proliferative and pro-apoptotic effects on breast adenocarcinoma through the induction of NADPH oxidase 1 and the alteration of mitochondrial morphology and dynamics

Cambogin exerts anti-proliferative and pro-apoptotic effects on breast adenocarcinoma through the induction of NADPH oxidase 1 and the alteration of mitochondrial morphology and dynamics

https://doi.org/10.18632/oncotarget.10585

Kaikai Shen, Fangfang Lu, Jianling Xie, Minfeng Wu, Bo Cai, Yurong Liu, Hong Zhang, Hongsheng Tan, Yingyi Pan,  and Hongxi Xu
50596-50611
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Significant change of cytochrome P450s activities in patients with hepatocellular carcinoma

Significant change of cytochrome P450s activities in patients with hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9437

Jun Zhou, Qiang Wen, Sai-Fei Li, Yun-Fei Zhang, Na Gao, Xin Tian, Yan Fang, Jie Gao, Ming-Zhu Cui, Xiao-Pei He, Lin-Jing Jia, Han Jin,  and Hai-Ling Qiao
50612-50623
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Phase II study of neoadjuvant therapy with nab-paclitaxel and cisplatin followed by surgery in patients with locally advanced esophageal squamous cell carcinoma

Phase II study of neoadjuvant therapy with nab-paclitaxel and cisplatin followed by surgery in patients with locally advanced esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.9562

Yun Fan, Youhua Jiang, Xinming Zhou, Qixun Chen, Zhiyu Huang, Yanjun Xu, Lei Gong, Haifeng Yu, Haiyan Yang, Jinshi Liu, Tao Lei, Qiang Zhao,  and Weimin Mao
50624-50634
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical factors that influence the outcome of selective devascularization in the treatment of portal hypertension

Clinical factors that influence the outcome of selective devascularization in the treatment of portal hypertension

https://doi.org/10.18632/oncotarget.9641

Cheng-Lin Lu, Ya-Juan Cao, Hao Cheng, Yi-Ming Pan, Shan-Hua Bao,  and Min Xie
50635-50642
Abstract  |  PDF  |  HTML  |  Order a Reprint

Outcomes of re-treatment with first-line trastuzumab plus a taxane in HER2 positive metastatic breast cancer patients after (neo)adjuvant trastuzumab: A prospective multicenter study

Outcomes of re-treatment with first-line trastuzumab plus a taxane in HER2 positive metastatic breast cancer patients after (neo)adjuvant trastuzumab: A prospective multicenter study

https://doi.org/10.18632/oncotarget.9331

Binghe Xu, Xichun Hu, Hong Zheng, Xiaojia Wang, Qingyuan Zhang, Shude Cui, Donggeng Liu, Ning Liao, Rongcheng Luo, Qiang Sun,  and Shiying Yu
50643-50655
Abstract  |  PDF  |  HTML  |  Order a Reprint

Efficacy of trastuzumab beyond progression in HER2 positive advanced gastric cancer: a multicenter prospective observational cohort study

Efficacy of trastuzumab beyond progression in HER2 positive advanced gastric cancer: a multicenter prospective observational cohort study

https://doi.org/10.18632/oncotarget.10456

Qian Li, Huiqin Jiang, Hong Li, Ruihua Xu, Lin Shen, Yiyi Yu, Yan Wang, Yuehong Cui, Wei Li, Shan Yu,  and Tianshu Liu
50656-50665
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

Long non-coding RNAs in normal and malignant hematopoiesis

Long non-coding RNAs in normal and malignant hematopoiesis

https://doi.org/10.18632/oncotarget.9308

Lucia Nobili, Marta Lionetti,  and Antonino Neri
50666-50681
Abstract  |  PDF  |  HTML  |  Order a Reprint

The signaling involved in autophagy machinery in keratinocytes and therapeutic approaches for skin diseases

The signaling involved in autophagy machinery in keratinocytes and therapeutic approaches for skin diseases

https://doi.org/10.18632/oncotarget.9330

Li Li, Xu Chen,  and Heng Gu
50682-50697
Abstract  |  PDF  |  HTML  |  Order a Reprint

The emerging roles of exosomes in leukemogeneis

The emerging roles of exosomes in leukemogeneis

https://doi.org/10.18632/oncotarget.9333

Jianbiao Zhou, Sam Wang, Kangyun Sun,  and Wee-Joo Chng
50698-50707
Abstract  |  PDF  |  HTML  |  Order a Reprint

Molecular factors in migraine

Molecular factors in migraine

https://doi.org/10.18632/oncotarget.9367

Marta Kowalska, Michał Prendecki, Wojciech Kozubski, Margarita Lianeri,  and Jolanta Dorszewska
50708-50718
Abstract  |  PDF  |  HTML  |  Order a Reprint

SETD2: an epigenetic modifier with tumor suppressor functionality

SETD2: an epigenetic modifier with tumor suppressor functionality

https://doi.org/10.18632/oncotarget.9368

Jun Li, Gerben Duns, Helga Westers, Rolf Sijmons, Anke van den Berg,  and Klaas Kok
50719-50734
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeting tumor-associated macrophages to combat pancreatic cancer

Targeting tumor-associated macrophages to combat pancreatic cancer

https://doi.org/10.18632/oncotarget.9383

Ran Cui, Wen Yue, Edmund C. Lattime, Mark N. Stein, Qing Xu,  and Xiang-Lin Tan
50735-50754
Abstract  |  PDF  |  HTML  |  Order a Reprint

The retinal determination gene network: from developmental regulator to cancer therapeutic target

The retinal determination gene network: from developmental regulator to cancer therapeutic target

https://doi.org/10.18632/oncotarget.9394

Deguang Kong, Yu Liu, Qian Liu, Na Han, Cuntai Zhang, Richard G. Pestell, Kongming Wu,  and Gaosong Wu
50755-50765
Abstract  |  PDF  |  HTML  |  Order a Reprint

The inflammasome: an emerging therapeutic oncotarget for cancer prevention

The inflammasome: an emerging therapeutic oncotarget for cancer prevention

https://doi.org/10.18632/oncotarget.9391

Wang Zhiyu, Neng Wang, Qi Wang, Cheng Peng, Jin Zhang, Pengxi Liu, Aihua Ou, Shaowen Zhong, Mario D. Cordero,  and Yi Lin
50766-50780
Abstract  |  PDF  |  HTML  |  Order a Reprint

Current relevance of hypoxia in head and neck cancer

Current relevance of hypoxia in head and neck cancer

https://doi.org/10.18632/oncotarget.9549

Marius G. Bredell, Jutta Ernst, Ilhem El-Kochairi, Yuliya Dahlem, Kristian Ikenberg,  and Desiree M. Schumann
50781-50804
Abstract  |  PDF  |  HTML  |  Order a Reprint

mTOR: An attractive therapeutic target for osteosarcoma?

mTOR: An attractive therapeutic target for osteosarcoma?

https://doi.org/10.18632/oncotarget.9305

Liu Ding, Liu Congwei, Qing Bei, Yang Tao, Wang Ruiguo, Yu Heze, Dou Bo,  and Li Zhihong
50805-50813
Abstract  |  PDF  |  HTML  |  Order a Reprint


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