Oncotarget

Vol 7, No 30

July 26, 2016

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Morphology of DMBA/TPA-induced epidermal tumors in mice with varying 14-3-3σ genotype. See Winter et al.

Table of Contents

Editorial: Autophagy and Cell Death

Stressed telomeres without POT1 enhance tumorigenesis

Stressed telomeres without POT1 enhance tumorigenesis

https://doi.org/10.18632/oncotarget.10600

Agnel Sfeir,  and Eros Lazzerini Denchi
46833-46834
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Priority Research Papers

Loss of T-cell quiescence by targeting Slfn2 prevents the development and progression of T-ALL

Loss of T-cell quiescence by targeting Slfn2 prevents the development and progression of T-ALL

https://doi.org/10.18632/oncotarget.9390

Aviya Goldshtein, Shani Mistriel Zerbib, Ibrahim Omar, Leonor Cohen-Daniel, Daniel Popkin,  and Michael Berger
46835-46847
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Knockout of MDA-9/Syntenin (SDCBP) expression in the microenvironment dampens tumor-supporting inflammation and inhibits melanoma metastasis

Knockout of MDA-9/Syntenin (SDCBP) expression in the microenvironment dampens tumor-supporting inflammation and inhibits melanoma metastasis

https://doi.org/10.18632/oncotarget.10040

Swadesh K. Das, Chunqing Guo, Anjan K. Pradhan, Praveen Bhoopathi, Sarmistha Talukdar, Xue-Ning Shen, Luni Emdad, Mark A. Subler, Jolene J. Windle, Devanand Sarkar, Xiang-Yang Wang,  and Paul B. Fisher
46848-46861
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Deletion of 14-3-3σ sensitizes mice to DMBA/TPA-induced papillomatosis

Deletion of 14-3-3σ sensitizes mice to DMBA/TPA-induced papillomatosis

https://doi.org/10.18632/oncotarget.10478

Markus Winter, Dmitri Lodygin, Berlinda Verdoodt,  and Heiko Hermeking
46862-46870
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Research Papers: Gerotarget (Focus on Aging)

Are TKIs favourable for the elderly with non-small-cell lung cancer?

Are TKIs favourable for the elderly with non-small-cell lung cancer?

https://doi.org/10.18632/oncotarget.9389

Sabrina Rossi, Ettore D’Argento, Giovanni Schinzari, Vincenzo Dadduzio, Vincenzo Di Noia, Alessandra Cassano,  and Carlo Barone
46871-46877
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Relationship of tobacco smoking and smoking-related DNA methylation with epigenetic age acceleration

Relationship of tobacco smoking and smoking-related DNA methylation with epigenetic age acceleration

https://doi.org/10.18632/oncotarget.9795

Xu Gao, Yan Zhang, Lutz Philipp Breitling,  and Hermann Brenner
46878-46889
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Relationship between LRRK2 R1628P polymorphism and Parkinson’s disease in Asian populations

Relationship between LRRK2 R1628P polymorphism and Parkinson’s disease in Asian populations

https://doi.org/10.18632/oncotarget.10378

Hui Zhao,  and Zhijun Kong
46890-46898
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The mitochondrial-derived peptide humanin activates the ERK1/2, AKT, and STAT3 signaling pathways and has age-dependent signaling differences in the hippocampus

The mitochondrial-derived peptide humanin activates the ERK1/2, AKT, and STAT3 signaling pathways and has age-dependent signaling differences in the hippocampus

https://doi.org/10.18632/oncotarget.10380

Su-Jeong Kim, Noel Guerrero, Gabriella Wassef, Jialin Xiao, Hemal H. Mehta, Pinchas Cohen,  and Kelvin Yen
46899-46912
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Cell surgery and growth factors in dry age-related macular degeneration: visual prognosis and morphological study

Cell surgery and growth factors in dry age-related macular degeneration: visual prognosis and morphological study

https://doi.org/10.18632/oncotarget.10442

Paolo Giuseppe Limoli, Celeste Limoli, Enzo Maria Vingolo, Sergio Zaccaria Scalinci,  and Marcella Nebbioso
46913-46923
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Activation of oncogenic tyrosine kinase signaling promotes insulin receptor-mediated cone photoreceptor survival

Activation of oncogenic tyrosine kinase signaling promotes insulin receptor-mediated cone photoreceptor survival

https://doi.org/10.18632/oncotarget.10447

Ammaji Rajala, Yuhong Wang,  and Raju V.S. Rajala
46924-46942
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Research Papers: Pathology

Inhibitory effect of thiacremonone on MPTP-induced dopaminergic neurodegeneration through inhibition of p38 activation

Inhibitory effect of thiacremonone on MPTP-induced dopaminergic neurodegeneration through inhibition of p38 activation

https://doi.org/10.18632/oncotarget.10504

Chul Ju Hwang, Hee Pom Lee, Dong-Young Choi, Heon Sang Jeong, Tae Hoon Kim, Tae Hyung Lee, Young Min Kim, Dae Bong Moon, Sung Sik Park, Sun Young Kim, Ki-Wan Oh, Dae Yeon Hwang, Sang-Bae Han, Hwa-Jeong Lee,  and Jin Tae Hong
46943-46958
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Sex-specific metabolic interactions between liver and adipose tissue in MCD diet-induced non-alcoholic fatty liver disease

Sex-specific metabolic interactions between liver and adipose tissue in MCD diet-induced non-alcoholic fatty liver disease

https://doi.org/10.18632/oncotarget.10506

Yun-Hee Lee, Sou Hyun Kim, Sang-Nam Kim, Hyun-Jung Kwon, Jeong-Dong Kim, Ji Youn Oh,  and Young-Suk Jung
46959-46971
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Research Papers: Immunology

AIM2 inhibits autophagy and IFN-β production during M. bovis infection

AIM2 inhibits autophagy and IFN-β production during M. bovis infection

https://doi.org/10.18632/oncotarget.10503

Chunfa Liu, Ruichao Yue, Yang Yang, Yongyong Cui, Lifeng Yang, Deming Zhao,  and Xiangmei Zhou
46972-46987
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Research Papers

Augmentation of response to nab-paclitaxel by inhibition of insulin-like growth factor (IGF) signaling in preclinical pancreatic cancer models

Augmentation of response to nab-paclitaxel by inhibition of insulin-like growth factor (IGF) signaling in preclinical pancreatic cancer models

https://doi.org/10.18632/oncotarget.9029

Niranjan Awasthi, Emily Scire, Sheena Monahan, Meghan Grojean, Eric Zhang, Margaret A. Schwarz,  and Roderich E. Schwarz
46988-47001
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A Phosphatidic Acid (PA) conveyor system of continuous intracellular transport from cell membrane to nucleus maintains EGF receptor homeostasis

A Phosphatidic Acid (PA) conveyor system of continuous intracellular transport from cell membrane to nucleus maintains EGF receptor homeostasis

https://doi.org/10.18632/oncotarget.9685

Karen M. Henkels, Taylor E. Miller, Ramya Ganesan, Brandon A. Wilkins, Kristen Fite,  and Julian Gomez-Cambronero
47002-47017
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Co-expression of wild-type FLT3 attenuates the inhibitory effect of FLT3 inhibitor on FLT3 mutated leukemia cells

Co-expression of wild-type FLT3 attenuates the inhibitory effect of FLT3 inhibitor on FLT3 mutated leukemia cells

https://doi.org/10.18632/oncotarget.10147

Fangli Chen, Yuichi Ishikawa, Akimi Akashi, Tomoki Naoe,  and Hitoshi Kiyoi
47018-47032
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A pan-cancer analysis of MYC-PVT1 reveals CNV-unmediated deregulation and poor prognosis in renal carcinoma

A pan-cancer analysis of MYC-PVT1 reveals CNV-unmediated deregulation and poor prognosis in renal carcinoma

https://doi.org/10.18632/oncotarget.9487

Ioana Posa, Silvia Carvalho, Joana Tavares,  and Ana Rita Grosso
47033-47041
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Peroxiredoxin 1 promotes invasion and migration by regulating epithelial-to-mesenchymal transition during oral carcinogenesis

Peroxiredoxin 1 promotes invasion and migration by regulating epithelial-to-mesenchymal transition during oral carcinogenesis

https://doi.org/10.18632/oncotarget.9705

Wenwen Niu, Min Zhang, Hui Chen, Chunxiao Wang, Ni Shi, Xinying Jing, Lihua Ge, Tong Chen,  and Xiaofei Tang
47042-47051
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Transcriptomic analysis of KSHV-infected primary oral fibroblasts: The role of interferon-induced genes in the latency of oncogenic virus

Transcriptomic analysis of KSHV-infected primary oral fibroblasts: The role of interferon-induced genes in the latency of oncogenic virus

https://doi.org/10.18632/oncotarget.9720

Lu Dai, Lihua Bai, Zhen Lin, Jing Qiao, Liang Yang, Erik K. Flemington, Jovanny Zabaleta,  and Zhiqiang Qin
47052-47060
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Identification of a new gene regulatory circuit involving B cell receptor activated signaling using a combined analysis of experimental, clinical and global gene expression data

Identification of a new gene regulatory circuit involving B cell receptor activated signaling using a combined analysis of experimental, clinical and global gene expression data

https://doi.org/10.18632/oncotarget.9219

Alexandra Schrader, Katharina Meyer, Neele Walther, Ailine Stolz, Maren Feist, Elisabeth Hand, Frederike von Bonin, Maurits Evers, Christian Kohler, Katayoon Shirneshan, Martina Vockerodt, Wolfram Klapper, Monika Szczepanowski, Paul G. Murray, Holger Bastians, Lorenz Trümper, Rainer Spang,  and Dieter Kube
47061-47081
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Mesenchymal stem cells in combination with erythropoietin repair hyperoxia-induced alveoli dysplasia injury in neonatal mice via inhibition of TGF-β1 signaling

Mesenchymal stem cells in combination with erythropoietin repair hyperoxia-induced alveoli dysplasia injury in neonatal mice via inhibition of TGF-β1 signaling

https://doi.org/10.18632/oncotarget.9314

Yun Luan, Luan Zhang, Sun Chao, Xiaoli Liu, Kaili Li, Yibiao Wang,  and Zhaohua Zhang
47082-47094
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SOX2 is essential for in vivo reprogramming of seminoma-like TCam-2 cells to an embryonal carcinoma-like fate

SOX2 is essential for in vivo reprogramming of seminoma-like TCam-2 cells to an embryonal carcinoma-like fate

https://doi.org/10.18632/oncotarget.9903

Daniel Nettersheim, Alena Heimsoeth, Sina Jostes, Simon Schneider, Martin Fellermeyer, Andrea Hofmann,  and Hubert Schorle
47095-47110
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Circulating tumour cells in regionally metastatic cutaneous squamous cell carcinoma: A pilot study

Circulating tumour cells in regionally metastatic cutaneous squamous cell carcinoma: A pilot study

https://doi.org/10.18632/oncotarget.9946

Tia Morosin, Bruce Ashford, Marie Ranson, Ruta Gupta, Jonathan Clark, N. Gopalakrishna Iyer,  and Kevin Spring
47111-47115
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Reduction of estradiol in human malignant pleural mesothelioma tissues may prevent tumour growth, as implied by in in-vivo and in-vitro models

Reduction of estradiol in human malignant pleural mesothelioma tissues may prevent tumour growth, as implied by in in-vivo and in-vitro models

https://doi.org/10.18632/oncotarget.9964

Barbara Nuvoli, Andrea Sacconi, Giancarlo Cortese, Sabrina Germoni, Bruno Murer,  and Rossella Galati
47116-47126
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Comprehensive genomic profiling of IgM multiple myeloma identifies IRF4 as a prognostic marker

Comprehensive genomic profiling of IgM multiple myeloma identifies IRF4 as a prognostic marker

https://doi.org/10.18632/oncotarget.9478

Daeun Ryu, Hee Jin Kim, Je-Gun Joung, Hae-Ock Lee, Joon Seol Bae, Seok Jin Kim, Haesu Kim, Woong-Yang Park,  and Kihyun Kim
47127-47133
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Albuminuria enhances NHE3 and NCC via stimulation of mitochondrial oxidative stress/angiotensin II axis

Albuminuria enhances NHE3 and NCC via stimulation of mitochondrial oxidative stress/angiotensin II axis

https://doi.org/10.18632/oncotarget.9972

Zhanjun Jia, Yibo Zhuang, Caiyu Hu, Xintong Zhang, Guixia Ding, Yue Zhang, Rajeev Rohatgi, Hu Hua, Songming Huang, John Ci-jiang He,  and Aihua Zhang
47134-47144
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FH535, a β-catenin pathway inhibitor, represses pancreatic cancer xenograft growth and angiogenesis

FH535, a β-catenin pathway inhibitor, represses pancreatic cancer xenograft growth and angiogenesis

https://doi.org/10.18632/oncotarget.9975

Lu Liu, Qiaoming Zhi, Meng Shen, Fei-Ran Gong, Binhua P. Zhou, Lian Lian, Bairong Shen, Kai Chen, Weiming Duan, Meng-Yao Wu, Min Tao,  and Wei Li
47145-47162
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Fas ligand and lytic granule differentially control cytotoxic dynamics of natural killer cell against cancer target

Fas ligand and lytic granule differentially control cytotoxic dynamics of natural killer cell against cancer target

https://doi.org/10.18632/oncotarget.9980

Yanting Zhu, Bo Huang,  and Jue Shi
47163-47172
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Characterization of metastatic tumor antigen 1 and its interaction with hepatitis B virus X protein in NF-κB signaling and tumor progression in a woodchuck hepatocellular carcinoma model

Characterization of metastatic tumor antigen 1 and its interaction with hepatitis B virus X protein in NF-κB signaling and tumor progression in a woodchuck hepatocellular carcinoma model

https://doi.org/10.18632/oncotarget.9986

Yung-Tsung Li, Chun-Jen Liu, Tung-Hung Su, Huei-Ru Cheng, Yung-Ming Jeng, Hsiu-Lin Lin, Chih-Chiang Wang, Jia-Horng Kao, Pei-Jer Chen, Ding-Shinn Chen,  and Hui-Lin Wu
47173-47185
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comprehensive analysis of differentially expressed profiles of lncRNAs and circRNAs with associated co-expression and ceRNA networks in bladder carcinoma

Comprehensive analysis of differentially expressed profiles of lncRNAs and circRNAs with associated co-expression and ceRNA networks in bladder carcinoma

https://doi.org/10.18632/oncotarget.9706

Mengge Huang, Zhenyu Zhong, Mengxin Lv, Jing Shu, Qiang Tian,  and Junxia Chen
47186-47200
Abstract  |  PDF  |  HTML  |  Order a Reprint

Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRβ2) splice variant in breast cancer

Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRβ2) splice variant in breast cancer

https://doi.org/10.18632/oncotarget.9719

Mary M. Heckler, Tizita Zewde Zeleke, Shailaja D. Divekar, Aileen I. Fernandez, Deanna M. Tiek, Jordan Woodrick, Alexander Farzanegan, Rabindra Roy, Aykut Üren, Susette C. Mueller,  and Rebecca B. Riggins
47201-47220
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Human cytomegalovirus may promote tumour progression by upregulating arginase-2

Human cytomegalovirus may promote tumour progression by upregulating arginase-2

https://doi.org/10.18632/oncotarget.9722

Helena Costa, Xinling Xu, Gitta Overbeek, Suhas Vasaikar, C. Pawan K. Patro, Ourania N. Kostopoulou, Masany Jung, Gowhar Shafi, Sharan Ananthaseshan, Giorgos Tsipras, Belghis Davoudi, Abdul-Aleem Mohammad, Hoyin Lam, Klas Strååt, Vanessa Wilhelmi, Mingmei Shang, Jesper Tegner, Joo Chuan Tong, Kum Thong Wong, Cecilia Söderberg-Naucler,  and Koon-Chu Yaiw
47221-47231
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Zingerone suppresses angiogenesis via inhibition of matrix metalloproteinases during tumor development

Zingerone suppresses angiogenesis via inhibition of matrix metalloproteinases during tumor development

https://doi.org/10.18632/oncotarget.10030

Woom-Yee Bae, Jae-Sun Choi, Ja-Eun Kim, Chan Park,  and Joo-Won Jeong
47232-47241
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Immunogenic cell death due to a new photodynamic therapy (PDT) with glycoconjugated chlorin (G-chlorin)

Immunogenic cell death due to a new photodynamic therapy (PDT) with glycoconjugated chlorin (G-chlorin)

https://doi.org/10.18632/oncotarget.9725

Mamoru Tanaka, Hiromi Kataoka, Shigenobu Yano, Takuya Sawada, Haruo Akashi, Masahiro Inoue, Shugo Suzuki, Yusuke Inagaki, Noriyuki Hayashi, Hirotada Nishie, Takaya Shimura, Tsutomu Mizoshita, Yoshinori Mori, Eiji Kubota, Satoshi Tanida, Satoru Takahashi,  and Takashi Joh
47242-47251
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comprehensive immunohistochemical analysis of tumor microenvironment immune status in esophageal squamous cell carcinoma

Comprehensive immunohistochemical analysis of tumor microenvironment immune status in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.10055

Ken Hatogai, Shigehisa Kitano, Satoshi Fujii, Takashi Kojima, Hiroyuki Daiko, Shogo Nomura, Takayuki Yoshino, Atsushi Ohtsu, Yuichi Takiguchi, Toshihiko Doi,  and Atsushi Ochiai
47252-47264
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinicopathological and prognostic significance of cyclooxygenase-2 expression in head and neck cancer: A meta-analysis

Clinicopathological and prognostic significance of cyclooxygenase-2 expression in head and neck cancer: A meta-analysis

https://doi.org/10.18632/oncotarget.10059

Bin Yang, Lin Jia, Qiaojuan Guo, Hui Ren, Yanping Hu,  and Tao Xie
47265-47277
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CDH1 rs9929218 variant at 16q22.1 contributes to colorectal cancer susceptibility

CDH1 rs9929218 variant at 16q22.1 contributes to colorectal cancer susceptibility

https://doi.org/10.18632/oncotarget.9758

Peng Han, Guiyou Liu, Xin Lu, Minmin Cao, Youling Yan, Jing Zou, Xiaobo Li,  and Guangyu Wang
47278-47286
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A novel capsid-modified oncolytic recombinant adenovirus type 5 for tumor-targeting gene therapy by intravenous route

A novel capsid-modified oncolytic recombinant adenovirus type 5 for tumor-targeting gene therapy by intravenous route

https://doi.org/10.18632/oncotarget.10075

Zhen Wang, Bin Yu, Baoming Wang, Jingyi Yan, Xiao Feng, Zixuan Wang, Lizheng Wang, Haihong Zhang, Hui Wu, Jiaxin Wu, Wei Kong,  and Xianghui Yu
47287-47301
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cidofovir is active against human papillomavirus positive and negative head and neck and cervical tumor cells by causing DNA damage as one of its working mechanisms

Cidofovir is active against human papillomavirus positive and negative head and neck and cervical tumor cells by causing DNA damage as one of its working mechanisms

https://doi.org/10.18632/oncotarget.10100

Barbara Mertens, Tatiane Nogueira, Ruzena Stranska, Lieve Naesens, Graciela Andrei,  and Robert Snoeck
47302-47318
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Bayesian network meta-analysis comparing five contemporary treatment strategies for newly diagnosed acute promyelocytic leukaemia

Bayesian network meta-analysis comparing five contemporary treatment strategies for newly diagnosed acute promyelocytic leukaemia

https://doi.org/10.18632/oncotarget.10118

Fenfang Wu, Di Wu, Yong Ren, Chongyang Duan, Shangwu Chen,  and Anlong Xu
47319-47331
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Plasma metabolomic analysis of human hepatocellular carcinoma: Diagnostic and therapeutic study

Plasma metabolomic analysis of human hepatocellular carcinoma: Diagnostic and therapeutic study

https://doi.org/10.18632/oncotarget.10119

Yang Chen, Jianyin Zhou, Jinquan Li, Jianghua Feng, Zhong Chen,  and Xiaomin Wang
47332-47342
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer

Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer

https://doi.org/10.18632/oncotarget.10121

James B. Greenaway, Carl Virtanen, Kata Osz, Tamas Revay, Daniel Hardy, Trevor Shepherd, Gabriel DiMattia,  and Jim Petrik
47343-47365
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Associations between smoking behavior-related alleles and the risk of melanoma

Associations between smoking behavior-related alleles and the risk of melanoma

https://doi.org/10.18632/oncotarget.10144

Wenting Wu, Hongliang Liu, Fengju Song, Li-Shiun Chen, Peter Kraft, Qingyi Wei,  and Jiali Han
47366-47375
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pseudogene BMI1P1 expression as a novel predictor for acute myeloid leukemia development and prognosis

Pseudogene BMI1P1 expression as a novel predictor for acute myeloid leukemia development and prognosis

https://doi.org/10.18632/oncotarget.10156

Ling-Yu Zhou, Ling-Ling Zhai, Jia-Yu Yin, Minse Evola-Deniz Vanessa, Jiao Zhou, Jing Zhang, Xi Tang, Jiang Lin, Jun Qian,  and Zhao-Qun Deng
47376-47386
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Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release

Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release

https://doi.org/10.18632/oncotarget.10159

Chenghui Liao, Kai Zheng, Yan Li, Hong Xu, Qiangrong Kang, Long Fan, Xiaopeng Hu, Zhe Jin, Yong Zeng, Xiaoli Kong, Jian Zhang, Xuli Wu, Haiqiang Wu, Lizhong Liu, Xiaohua Xiao, Yifei Wang,  and Zhendan He
47387-47402
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Phosphorylation of mTOR Ser2481 is a key target limiting the efficacy of rapalogs for treating hepatocellular carcinoma

Phosphorylation of mTOR Ser2481 is a key target limiting the efficacy of rapalogs for treating hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.10161

Kosuke Watari, Ayumi Nishitani, Tomohiro Shibata, Masaki Noda, Akihiko Kawahara, Jun Akiba, Yuichi Murakami, Hirohisa Yano, Michihiko Kuwano,  and Mayumi Ono
47403-47417
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of new candidate therapeutic target genes in head and neck squamous cell carcinomas

Identification of new candidate therapeutic target genes in head and neck squamous cell carcinomas

https://doi.org/10.18632/oncotarget.10163

Marie-Paule Sablin, Coraline Dubot, Jerzy Klijanienko, Sophie Vacher, Lamia Ouafi, Walid Chemlali, Martial Caly, Xavier Sastre-Garau, Emmanuelle Lappartient, Odette Mariani, José Rodriguez, Thomas Jouffroy, Angélique Girod, Valentin Calugaru, Caroline Hoffmann, Rosette Lidereau, Frédérique Berger, Maud Kamal, Ivan Bieche,  and Christophe Le Tourneau
47418-47430
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value of the expression of cancer stem cell-related markers CD133 and CD44 in hepatocellular carcinoma: From patients to patient-derived tumor xenograft models

Prognostic value of the expression of cancer stem cell-related markers CD133 and CD44 in hepatocellular carcinoma: From patients to patient-derived tumor xenograft models

https://doi.org/10.18632/oncotarget.10164

Qihong Zhao, Heng Zhou, Qifei Liu, Ye Cao, Gang Wang, Anla Hu, Liang Ruan, Sufang Wang, Qingli Bo, Wenjun Chen, Chuanlai Hu, Dexiang Xu, Fangbiao Tao, Jiyu Cao, Yongsheng Ge, Zongfan Yu, Li Li,  and Hua Wang
47431-47443
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-4638-5p inhibits castration resistance of prostate cancer through repressing Kidins220 expression and PI3K/AKT pathway activity

MiR-4638-5p inhibits castration resistance of prostate cancer through repressing Kidins220 expression and PI3K/AKT pathway activity

https://doi.org/10.18632/oncotarget.10165

Yang Wang, Ning Shao, Xueying Mao, Minmin Zhu, Weifei Fan, Zhixiang Shen, Rong Xiao, Chuncai Wang, Wenping Bao, Xinyu Xu, Chun Yang, Jian Dong, Deshui Yu, Yan Wu, Caixia Zhu, Liting Wen, Xiaojie Lu, Yong-Jie Lu,  and Ninghan Feng
47444-47464
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors

https://doi.org/10.18632/oncotarget.10167

Amanda M. Smith, Matthew D. Dun, Erwin M. Lee, Celeste Harrison, Richard Kahl, Hayley Flanagan, Nikita Panicker, Baratali Mashkani, Anthony S. Don, Jonathan Morris, Hamish Toop, Richard B. Lock, Jason A. Powell, Daniel Thomas, Mark A. Guthridge, Andrew Moore, Leonie K. Ashman, Kathryn A. Skelding, Anoop Enjeti,  and Nicole M. Verrills
47465-47478
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dextran-Catechin: An anticancer chemically-modified natural compound targeting copper that attenuates neuroblastoma growth

Dextran-Catechin: An anticancer chemically-modified natural compound targeting copper that attenuates neuroblastoma growth

https://doi.org/10.18632/oncotarget.10201

Orazio Vittorio, Miriam Brandl, Giuseppe Cirillo, Kathleen Kimpton, Elizabeth Hinde, Katharina Gaus, Eugene Yee, Naresh Kumar, Hien Duong, Claudia Fleming, Michelle Haber, Murray Norris, Cyrille Boyer,  and Maria Kavallaris
47479-47493
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Exogenous pyruvate facilitates cancer cell adaptation to hypoxia by serving as an oxygen surrogate

Exogenous pyruvate facilitates cancer cell adaptation to hypoxia by serving as an oxygen surrogate

https://doi.org/10.18632/oncotarget.10202

Chengqian Yin, Dan He, Shuyang Chen, Xiaoling Tan,  and Nianli Sang
47494-47510
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Characterization of the CD49f+/CD44+/CD24 single-cell derived stem cell population in basal-like DCIS cells

Characterization of the CD49f+/CD44+/CD24 single-cell derived stem cell population in basal-like DCIS cells

https://doi.org/10.18632/oncotarget.10203

Nadire Duru, Ramkishore Gernapudi, Pang-Kuo Lo, Yuan Yao, Benjamin Wolfson, Yongshu Zhang,  and Qun Zhou
47511-47525
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Preparation study of indocyanine green-rituximab: A new receptor-targeted tracer for sentinel lymph node in breast cancer

Preparation study of indocyanine green-rituximab: A new receptor-targeted tracer for sentinel lymph node in breast cancer

https://doi.org/10.18632/oncotarget.10204

Bin-Bin Cong, Xiao Sun, Xian-Rang Song, Yan-Bing Liu, Tong Zhao, Xiao-Shan Cao, Peng-Fei Qiu, Chong-Lin Tian, Jin-Ming Yu,  and Yong-Sheng Wang
47526-47535
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Downregulation of long non-coding RNA ANRIL suppresses lymphangiogenesis and lymphatic metastasis in colorectal cancer

Downregulation of long non-coding RNA ANRIL suppresses lymphangiogenesis and lymphatic metastasis in colorectal cancer

https://doi.org/10.18632/oncotarget.9868

Zhenqiang Sun, Chunlin Ou, Weiguo Ren, Xiang Xie, Xiayu Li,  and Guiyuan Li
47536-47555
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Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model

Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model

https://doi.org/10.18632/oncotarget.9879

Takashi Murakami, Arun S. Singh, Tasuku Kiyuna, Sarah M. Dry, Yunfeng Li, Aaron W. James, Kentaro Igarashi, Kei Kawaguchi, Jonathan C. DeLong, Yong Zhang, Yukihiko Hiroshima, Tara Russell, Mark A. Eckardt, Jane Yanagawa, Noah Federman, Ryusei Matsuyama, Takashi Chishima, Kuniya Tanaka, Michael Bouvet, Itaru Endo, Fritz C. Eilber,  and Robert M. Hoffman
47556-47564
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Activation of the orphan receptor GPR55 by lysophosphatidylinositol promotes metastasis in triple-negative breast cancer

Activation of the orphan receptor GPR55 by lysophosphatidylinositol promotes metastasis in triple-negative breast cancer

https://doi.org/10.18632/oncotarget.10206

Clara Andradas, Sandra Blasco-Benito, Sonia Castillo-Lluva, Patricia Dillenburg-Pilla, Rebeca Diez-Alarcia, Alba Juanes-García, Elena García-Taboada, Rodrigo Hernando-Llorente, Joaquim Soriano, Sigrid Hamann, Antonia Wenners, Ibrahim Alkatout, Wolfram Klapper, Christoph Rocken, Maret Bauer, Norbert Arnold, Miguel Quintanilla, Diego Megías, Miguel Vicente-Manzanares, Leyre Urigüen, J. Silvio Gutkind, Manuel Guzmán, Eduardo Pérez-Gómez,  and Cristina Sánchez
47565-47575
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

NO-dependent attenuation of TPA-induced immunoinflammatory skin changes in Balb/c mice by pindolol, heptaminol or ATRA, but not by verapamil

NO-dependent attenuation of TPA-induced immunoinflammatory skin changes in Balb/c mice by pindolol, heptaminol or ATRA, but not by verapamil

https://doi.org/10.18632/oncotarget.10217

Jinhyuk F. Chung, Calvin J. Yoon, Seon Ah Cheon, Eun Seok Seo, Sung Ho Park, Jae Seung Yang, Bumju Kim, Min Young Joo, Tae Jung Park, Ki Hean Kim, Anil K. Sood,  and Sang Joon Lee
47576-47585
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Increased cancer stem cell invasion is mediated by myosin IIB and nuclear translocation

Increased cancer stem cell invasion is mediated by myosin IIB and nuclear translocation

https://doi.org/10.18632/oncotarget.9896

Dustin Thomas, Praveena S. Thiagarajan, Vandana Rai, Ofer Reizes, Justin Lathia,  and Thomas Egelhoff
47586-47592
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LINC00052 regulates the expression of NTRK3 by miR-128 and miR-485-3p to strengthen HCC cells invasion and migration

LINC00052 regulates the expression of NTRK3 by miR-128 and miR-485-3p to strengthen HCC cells invasion and migration

https://doi.org/10.18632/oncotarget.10250

Dongmei Xiong, Yanrui Sheng, Shijia Ding, Juan Chen, Xixi Tan, Tao Zeng, Dongdong Qin, Liying Zhu, Ailong Huang,  and Hua Tang
47593-47608
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MMP7 interacts with ARF in nucleus to potentiate tumor microenvironments for prostate cancer progression in vivo

MMP7 interacts with ARF in nucleus to potentiate tumor microenvironments for prostate cancer progression in vivo

https://doi.org/10.18632/oncotarget.10251

Yingqiu Xie, Wenfu Lu, Shenji Liu, Qing Yang, J. Shawn Goodwin, Sandeep Anantha Sathyanarayana, Siddharth Pratap,  and Zhenbang Chen
47609-47619
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Suppression of ABHD2, identified through a functional genomics screen, causes anoikis resistance, chemoresistance and poor prognosis in ovarian cancer

Suppression of ABHD2, identified through a functional genomics screen, causes anoikis resistance, chemoresistance and poor prognosis in ovarian cancer

https://doi.org/10.18632/oncotarget.9951

Koji Yamanoi, Noriomi Matsumura, Susan K. Murphy, Tsukasa Baba, Kaoru Abiko, Junzo Hamanishi, Ken Yamaguchi, Masafumi Koshiyama, Ikuo Konishi,  and Masaki Mandai
47620-47636
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CCR4 promotes metastasis via ERK/NF-κB/MMP13 pathway and acts downstream of TNF-α in colorectal cancer

CCR4 promotes metastasis via ERK/NF-κB/MMP13 pathway and acts downstream of TNF-α in colorectal cancer

https://doi.org/10.18632/oncotarget.10256

Baochi Ou, Jingkun Zhao, Shaopei Guan, Hao Feng, Xiongzhi Wangpu, Congcong Zhu, Yaping Zong, Junjun Ma, Jing Sun, Xiaohui Shen, Minhua Zheng,  and Aiguo Lu
47637-47649
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Obesity does not promote tumorigenesis of localized patient-derived prostate cancer xenografts

Obesity does not promote tumorigenesis of localized patient-derived prostate cancer xenografts

https://doi.org/10.18632/oncotarget.10258

Jennifer C.Y. Lo, Ashlee K. Clark, Natasha Ascui, Mark Frydenberg, Gail P. Risbridger, Renea A. Taylor,  and Matthew J. Watt
47650-47662
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The modulation of Dicer regulates tumor immunogenicity in melanoma

The modulation of Dicer regulates tumor immunogenicity in melanoma

https://doi.org/10.18632/oncotarget.10273

Nicholas C. Hoffend, William J. Magner,  and Thomas B. Tomasi
47663-47673
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Cyclin D1 represses peroxisome proliferator-activated receptor alpha and inhibits fatty acid oxidation

Cyclin D1 represses peroxisome proliferator-activated receptor alpha and inhibits fatty acid oxidation

https://doi.org/10.18632/oncotarget.10274

Sushama Kamarajugadda, Jennifer R. Becker, Eric A. Hanse, Douglas G. Mashek, Mara T. Mashek, Anna M. Hendrickson, Lisa K. Mullany,  and Jeffrey H. Albrecht
47674-47686
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LACE1 interacts with p53 and mediates its mitochondrial translocation and apoptosis

LACE1 interacts with p53 and mediates its mitochondrial translocation and apoptosis

https://doi.org/10.18632/oncotarget.9959

Jana Cesnekova, Jana Spacilova, Hana Hansikova, Josef Houstek, Jiri Zeman,  and Lukas Stiburek
47687-47698
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BRAFV600E-dependent Mcl-1 stabilization leads to everolimus resistance in colon cancer cells

BRAFV600E-dependent Mcl-1 stabilization leads to everolimus resistance in colon cancer cells

https://doi.org/10.18632/oncotarget.10277

Kan He, Dongshi Chen, Hang Ruan, Xiangyun Li, Jingshan Tong, Xiang Xu, Lin Zhang,  and Jian Yu
47699-47710
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Vascular endothelial growth factor polymorphisms are associated with osteosarcoma susceptibility

Vascular endothelial growth factor polymorphisms are associated with osteosarcoma susceptibility

https://doi.org/10.18632/oncotarget.10278

Yuan-Yuan Hu, Xin-Ya Du, Ai-Ling Zhan, Lan Zhou, Qian Jiang, Yu-Ming Niu,  and Ming Shen
47711-47719
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Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10

Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10

https://doi.org/10.18632/oncotarget.10279

Patricia A. Madureira, Alamelu G. Bharadwaj, Moamen Bydoun, Katy Garant, Paul O'Connell, Patrick Lee,  and David M. Waisman
47720-47737
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Carbon ion irradiation withstands cancer stem cells’ migration/invasion process in Head and Neck Squamous Cell Carcinoma (HNSCC)

Carbon ion irradiation withstands cancer stem cells’ migration/invasion process in Head and Neck Squamous Cell Carcinoma (HNSCC)

https://doi.org/10.18632/oncotarget.10281

Coralie Moncharmont, Jean-Baptiste Guy, Anne-Sophie Wozny, Marion Gilormini, Priscilla Battiston-Montagne, Dominique Ardail, Michael Beuve, Gersende Alphonse, Xavier Simoëns, Chloé Rancoule, Claire Rodriguez-Lafrasse,  and Nicolas Magné
47738-47749
Abstract  |  PDF  |  HTML  |  Order a Reprint

An overall and dose-response meta-analysis for thyrotropin and thyroid cancer risk by histological type

An overall and dose-response meta-analysis for thyrotropin and thyroid cancer risk by histological type

https://doi.org/10.18632/oncotarget.10282

Na Hu, Zhan-Ming Li, Jin-Feng Liu, Zhen-Zhen Zhang,  and Li-Shun Wang
47750-47759
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MicroRNA-27a promotes renal tubulointerstitial fibrosis via suppressing PPARγ pathway in diabetic nephropathy

MicroRNA-27a promotes renal tubulointerstitial fibrosis via suppressing PPARγ pathway in diabetic nephropathy

https://doi.org/10.18632/oncotarget.10283

Xiaoyan Hou, Jianwei Tian, Jian Geng, Xiao Li, Xun Tang, Jun Zhang,  and Xiaoyan Bai
47760-47776
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Epidermal growth factor receptor inhibitors trigger a type I interferon response in human skin

Epidermal growth factor receptor inhibitors trigger a type I interferon response in human skin

https://doi.org/10.18632/oncotarget.10013

Daniela Lulli, Maria Luigia Carbone,  and Saveria Pastore
47777-47793
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Effect of oral antiviral treatment on long-term outcomes of radiofrequency ablation therapy for hepatitis B virus-related hepatocellular carcinoma

Effect of oral antiviral treatment on long-term outcomes of radiofrequency ablation therapy for hepatitis B virus-related hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.10026

Won Sohn, Tae Wook Kang, Sun-Kyu Choi, Sin-Ho Jung, Min Woo Lee, Hyo Keun Lim, Ju-Yeon Cho, Sang Goon Shim, Dong Hyun Sinn, Geum-Youn Gwak, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik, Hyunchul Rhim,  and Yong-Han Paik
47794-47807
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hypoxia upregulates HIG2 expression and contributes to bevacizumab resistance in glioblastoma

Hypoxia upregulates HIG2 expression and contributes to bevacizumab resistance in glioblastoma

https://doi.org/10.18632/oncotarget.10029

Xing-gang Mao, Chao Wang, Dong-ye Liu, Xiang Zhang, Liang Wang, Ming Yan, Wei Zhang, Jun Zhu, Zi-chao Li, Chen Mi, Jing-yang Tian, Guang-dong Hou, Si-yu Miao, Zi-xuan Song, Jin-cheng Li,  and Xiao-yan Xue
47808-47820
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Analysis of tissue and circulating microRNA expression during metaplastic transformation of the esophagus

Analysis of tissue and circulating microRNA expression during metaplastic transformation of the esophagus

https://doi.org/10.18632/oncotarget.10291

Daniela Cabibi, Stefano Caruso, Viviana Bazan, Marta Castiglia, Giuseppe Bronte, Sabrina Ingrao, Daniele Fanale, Antonina Cangemi, Valentina Calò, Angela Listì, Lorena Incorvaia, Antonio Galvano, Gianni Pantuso, Eugenio Fiorentino, Sergio Castorina,  and Antonio Russo
47821-47830
Abstract  |  PDF  |  HTML  |  Order a Reprint

Proteomic analyses of brain tumor cell lines amidst the unfolded protein response

Proteomic analyses of brain tumor cell lines amidst the unfolded protein response

https://doi.org/10.18632/oncotarget.10032

Jasmina S. Redzic, Joe D. Gomez, Justin E. Hellwinkel, Thomas J. Anchordoquy,  and Michael W. Graner
47831-47847
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Antitumor efficacy of the heparan sulfate mimic roneparstat (SST0001) against sarcoma models involves multi-target inhibition of receptor tyrosine kinases

Antitumor efficacy of the heparan sulfate mimic roneparstat (SST0001) against sarcoma models involves multi-target inhibition of receptor tyrosine kinases

https://doi.org/10.18632/oncotarget.10292

Giuliana Cassinelli, Enrica Favini, Laura Dal Bo, Monica Tortoreto, Marcella De Maglie, Gianpaolo Dagrada, Silvana Pilotti, Franco Zunino, Nadia Zaffaroni,  and Cinzia Lanzi
47848-47863
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IntNetLncSim: an integrative network analysis method to infer human lncRNA functional similarity

IntNetLncSim: an integrative network analysis method to infer human lncRNA functional similarity

https://doi.org/10.18632/oncotarget.10012

Liang Cheng, Hongbo Shi, Zhenzhen Wang, Yang Hu, Haixiu Yang, Chen Zhou, Jie Sun,  and Meng Zhou
47864-47874
Abstract  |  PDF  |  HTML  |  Order a Reprint

RPL27A is a target of miR-595 and may contribute to the myelodysplastic phenotype through ribosomal dysgenesis

RPL27A is a target of miR-595 and may contribute to the myelodysplastic phenotype through ribosomal dysgenesis

https://doi.org/10.18632/oncotarget.10293

Heba A. Alkhatabi, Donal P. McLornan, Austin G. Kulasekararaj, Farooq Malik, Thomas Seidl, David Darling, Joop Gaken,  and Ghulam J. Mufti
47875-47890
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The essential role of GATA transcription factors in adult murine prostate

The essential role of GATA transcription factors in adult murine prostate

https://doi.org/10.18632/oncotarget.10294

Lijuan Xiao, Qin Feng, Zheng Zhang, Fen Wang, John P. Lydon, Michael M. Ittmann, Li Xin, Nicholas Mitsiades,  and Bin He
47891-47903
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Laminin-111 peptide C16 regulates invadopodia activity of malignant cells through β1 integrin, Src and ERK 1/2

Laminin-111 peptide C16 regulates invadopodia activity of malignant cells through β1 integrin, Src and ERK 1/2

https://doi.org/10.18632/oncotarget.10062

Adriane S. Siqueira, Monique P. Pinto, Mário C. Cruz, Basilio Smuczek, Karen S.P. Cruz, José Alexandre M. Barbuto, Daisuke Hoshino, Alissa M. Weaver, Vanessa M. Freitas,  and Ruy G. Jaeger
47904-47917
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TP53 codon 72 polymorphism may predict early tumour progression in paediatric pilocytic astrocytoma

TP53 codon 72 polymorphism may predict early tumour progression in paediatric pilocytic astrocytoma

https://doi.org/10.18632/oncotarget.10295

Samantha Mascelli, Paolo Nozza, David T.W. Jones, Carole Colin, Angela Pistorio, Claudia Milanaccio, Marcello Ravegnani, Alessandro Consales, Olaf Witt, Giovanni Morana, Armando Cama, Valeria Capra, Roberto Biassoni, Stefan M. Pfister, Dominique Figarella-Branger, Maria Luisa Garrè,  and Alessandro Raso
47918-47926
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The calpain system is associated with survival of breast cancer patients with large but operable inflammatory and non-inflammatory tumours treated with neoadjuvant chemotherapy

The calpain system is associated with survival of breast cancer patients with large but operable inflammatory and non-inflammatory tumours treated with neoadjuvant chemotherapy

https://doi.org/10.18632/oncotarget.10066

Sarah J. Storr, Siwei Zhang, Tim Perren, Mark Lansdown, Hiba Fatayer, Nisha Sharma, Renu Gahlaut, Abeer Shaaban,  and Stewart G. Martin
47927-47937
Abstract  |  PDF  |  HTML  |  Order a Reprint

EFEMP1 promotes ovarian cancer cell growth, invasion and metastasis via activated the AKT pathway

EFEMP1 promotes ovarian cancer cell growth, invasion and metastasis via activated the AKT pathway

https://doi.org/10.18632/oncotarget.10296

Xiuxiu Yin, Shuang Fang, Mei Wang, Qiang Wang, Rui Fang,  and Jie Chen
47938-47953
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Vitamin C uncouples the Warburg metabolic switch in KRAS mutant colon cancer

Vitamin C uncouples the Warburg metabolic switch in KRAS mutant colon cancer

https://doi.org/10.18632/oncotarget.10087

Oscar Aguilera, María Muñoz-Sagastibelza, Blanca Torrejón, Aurea Borrero-Palacios, Laura del Puerto-Nevado, Javier Martínez-Useros, María Rodriguez-Remirez, Sandra Zazo, Estela García, Mario Fraga, Federico Rojo,  and Jesús García-Foncillas
47954-47965
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic variants in regulatory regions of microRNAs are associated with lung cancer risk

Genetic variants in regulatory regions of microRNAs are associated with lung cancer risk

https://doi.org/10.18632/oncotarget.10299

Kaipeng Xie, Cheng Wang, Na Qin, Jianshui Yang, Meng Zhu, Juncheng Dai, Guangfu Jin, Hongbing Shen, Hongxia Ma,  and Zhibin Hu
47966-47974
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Patterns of distant metastasis in Chinese women according to breast cancer subtypes

Patterns of distant metastasis in Chinese women according to breast cancer subtypes

https://doi.org/10.18632/oncotarget.10099

San-Gang Wu, Jia-Yuan Sun, Li-Chao Yang, Li-Ying Tang, Xue Wang, Xue-Ting Chen, Gui-Hua Liu, Huan-Xin Lin, Qin Lin,  and Zhen-Yu He
47975-47984
Abstract  |  PDF  |  HTML  |  Order a Reprint

FOXM1 promotes reprogramming of glucose metabolism in epithelial ovarian cancer cells via activation of GLUT1 and HK2 transcription

FOXM1 promotes reprogramming of glucose metabolism in epithelial ovarian cancer cells via activation of GLUT1 and HK2 transcription

https://doi.org/10.18632/oncotarget.10103

Yu Wang, Yuyu Yun, Bo Wu, Li Wen, Mingling Wen, Huiling Yang, Lisheng Zhao, Wenchao Liu, Suyun Huang, Ning Wen,  and Yu Li
47985-47997
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Polo-like kinase 1 inhibition diminishes acquired resistance to epidermal growth factor receptor inhibition in non-small cell lung cancer with T790M mutations

Polo-like kinase 1 inhibition diminishes acquired resistance to epidermal growth factor receptor inhibition in non-small cell lung cancer with T790M mutations

https://doi.org/10.18632/oncotarget.10332

Yuehong Wang, Ratnakar Singh, Liguang Wang, Monique Nilsson, Ruchitha Goonatilake, Pan Tong, Lerong Li, Uma Giri, Pamela Villalobos, Barbara Mino, Jaime Rodriguez-Canales, Ignacio Wistuba, Jing Wang, John V. Heymach,  and Faye M. Johnson
47998-48010
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dual tumor suppressing and promoting function of Notch1 signaling in human prostate cancer

Dual tumor suppressing and promoting function of Notch1 signaling in human prostate cancer

https://doi.org/10.18632/oncotarget.10333

Karine Lefort, Paola Ostano, Maurizia Mello-Grand, Valérie Calpini, Maria Scatolini, Antonella Farsetti, Gian Paolo Dotto,  and Giovanna Chiorino
48011-48026
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dragon (RGMb) induces oxaliplatin resistance in colon cancer cells

Dragon (RGMb) induces oxaliplatin resistance in colon cancer cells

https://doi.org/10.18632/oncotarget.10338

Ying Shi, Xiao-Xiao Huang, Guo-Bin Chen, Ying Wang, Qiang Zhi, Yuan-Sheng Liu, Xiao-Ling Wu, Li-Fen Wang, Bing Yang, Chuan-Xing Xiao, Hui-Qin Xing, Jian-Lin Ren, Yin Xia,  and Bayasi Guleng
48027-48037
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression of the SIBLINGs and their MMP partners in human benign and malignant prostate neoplasms

Expression of the SIBLINGs and their MMP partners in human benign and malignant prostate neoplasms

https://doi.org/10.18632/oncotarget.10110

Charles C. Anunobi, Komal Koli, Geetu Saxena, Adekunbiola A. Banjo,  and Kalu U.E. Ogbureke
48038-48049
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression of AKR1C3 significantly enhances human prostate cancer cells resistance to radiation

Overexpression of AKR1C3 significantly enhances human prostate cancer cells resistance to radiation

https://doi.org/10.18632/oncotarget.10347

Shao-Qian Sun, Xiaobin Gu, Xian-Shu Gao, Yi Li, Hongliang Yu, Wei Xiong, Hao Yu, Wen Wang, Yingbo Li, Yingqi Teng,  and Demin Zhou
48050-48058
Abstract  |  PDF  |  HTML  |  Order a Reprint

The emergence of T790M mutation in EGFR-mutant lung adenocarcinoma patients having a history of acquired resistance to EGFR-TKI: focus on rebiopsy timing and long-term existence of T790M

The emergence of T790M mutation in EGFR-mutant lung adenocarcinoma patients having a history of acquired resistance to EGFR-TKI: focus on rebiopsy timing and long-term existence of T790M

https://doi.org/10.18632/oncotarget.10351

Jeng-Sen Tseng, Kang-Yi Su, Tsung-Ying Yang, Kun-Chieh Chen, Kuo-Hsuan Hsu, Hsuan-Yu Chen, Chi-Ren Tsai, Sung-Liang Yu,  and Gee-Chen Chang
48059-48069
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Transcriptome sequencing of neurologic diseases associated genes in HHV-6A infected human astrocyte

Transcriptome sequencing of neurologic diseases associated genes in HHV-6A infected human astrocyte

https://doi.org/10.18632/oncotarget.10127

Qing Shao, Zhe Lin, Xiaohui Wu, Junwei Tang, Shuai Lu, Dongju Feng, Ci Cheng, Lanqun Qing, Kun Yao,  and Yun Chen
48070-48080
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells

NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells

https://doi.org/10.18632/oncotarget.10129

Clarissa Ribeiro Reily Rocha, Gustavo Satoru Kajitani, Annabel Quinet, Rodrigo Soares Fortunato,  and Carlos Frederico Martins Menck
48081-48092
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prolactin signaling through focal adhesion complexes is amplified by stiff extracellular matrices in breast cancer cells

Prolactin signaling through focal adhesion complexes is amplified by stiff extracellular matrices in breast cancer cells

https://doi.org/10.18632/oncotarget.10137

Craig E. Barcus, Patricia J. Keely, Kevin W. Eliceiri,  and Linda A. Schuler
48093-48106
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Downregulation of HP1α suppresses proliferation of cholangiocarcinoma by restoring SFRP1 expression

Downregulation of HP1α suppresses proliferation of cholangiocarcinoma by restoring SFRP1 expression

https://doi.org/10.18632/oncotarget.10371

Wenlong Cheng, Li Tian, Bing Wang, Yongqiang Qi, Wenhua Huang, Hongbo Li,  and Yong-Jun Chen
48107-48119
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High-grade squamous intraepithelial lesion arising adjacent to vulvar lymphangioma circumscriptum: a tertiary institutional experience

High-grade squamous intraepithelial lesion arising adjacent to vulvar lymphangioma circumscriptum: a tertiary institutional experience

https://doi.org/10.18632/oncotarget.10158

Go Eun Bae, Gun Yoon, Yong Jung Song,  and Hyun-Soo Kim
48120-48129
Abstract  |  PDF  |  HTML  |  Order a Reprint

Polymorphisms of multiple genes involved in NER pathway predict prognosis of gastric cancer

Polymorphisms of multiple genes involved in NER pathway predict prognosis of gastric cancer

https://doi.org/10.18632/oncotarget.10173

Jingwei Liu, Na Deng, Qian Xu, Liping Sun, Huakang Tu, Zhenning Wang, Chengzhong Xing,  and Yuan Yuan
48130-48142
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The number of tumorspheres cultured from peripheral blood is a predictor for presence of metastasis in patients with breast cancer

The number of tumorspheres cultured from peripheral blood is a predictor for presence of metastasis in patients with breast cancer

https://doi.org/10.18632/oncotarget.10174

Monika Pizon, Dorothea Schott, Ulrich Pachmann,  and Katharina Pachmann
48143-48154
Abstract  |  PDF  |  HTML  |  Order a Reprint

AKT-induced PKM2 phosphorylation signals for IGF-1-stimulated cancer cell growth

AKT-induced PKM2 phosphorylation signals for IGF-1-stimulated cancer cell growth

https://doi.org/10.18632/oncotarget.10179

Young Soo Park, Dong Joon Kim, Han Koo, Se Hwan Jang, Yeon-Mi You, Jung Hee Cho, Suk-Jin Yang, Eun Sil Yu, Yuri Jung, Dong Chul Lee, Jung-Ae Kim, Zee-Yong Park, Kyung Chan Park,  and Young Il Yeom
48155-48167
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expected long-term impact of screening endoscopy on colorectal cancer incidence: a modelling study

Expected long-term impact of screening endoscopy on colorectal cancer incidence: a modelling study

https://doi.org/10.18632/oncotarget.10178

Hermann Brenner, Jens Kretschmann, Christian Stock,  and Michael Hoffmeister
48168-48179
Abstract  |  PDF  |  HTML  |  Order a Reprint

Chamaejasmenin B, a novel candidate, inhibits breast tumor metastasis by rebalancing TGF-beta paradox

Chamaejasmenin B, a novel candidate, inhibits breast tumor metastasis by rebalancing TGF-beta paradox

https://doi.org/10.18632/oncotarget.10193

Qi Li, Yajie Wang, Hongbin Xiao, Yujie Li, Xiaoxi Kan, Xiaomin Wang, Ganlin Zhang, Zhixin Wang, Qing Yang, Xi Chen, Xiaogang Weng, Ying Chen, Bingbing Zhou, Yan Guo, Xucen Liu,  and Xiaoxin Zhu
48180-48192
Abstract  |  PDF  |  HTML  |  Order a Reprint

MT2-MMP induces proteolysis and leads to EMT in carcinomas

MT2-MMP induces proteolysis and leads to EMT in carcinomas

https://doi.org/10.18632/oncotarget.10194

Yusi Liu, Xiaojiao Sun, Jinfa Feng, Li-Li Deng, Yihao Liu, Bokang Li, Mingyue Zhu, Changlian Lu,  and Lingyun Zhou
48193-48205
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting mTOR pathway inhibits tumor growth in different molecular subtypes of triple-negative breast cancers

Targeting mTOR pathway inhibits tumor growth in different molecular subtypes of triple-negative breast cancers

https://doi.org/10.18632/oncotarget.10195

Rana Hatem, Rania El Botty, Sophie Chateau-Joubert, Jean-Luc Servely, Dalila Labiod, Ludmilla de Plater, Franck Assayag, Florence Coussy, Céline Callens, Sophie Vacher, Fabien Reyal, Sabina Cosulich, Véronique Diéras, Ivan Bièche,  and Elisabetta Marangoni
48206-48219
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Suppression of APC/CCdh1 has subtype specific biological effects in acute myeloid leukemia

Suppression of APC/CCdh1 has subtype specific biological effects in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.10196

Daniel Ewerth, Andrea Schmidts, Manuel Hein, Dominik Schnerch, Arunas Kvainickas, Christine Greil, Justus Duyster, Monika Engelhardt,  and Ralph Wäsch
48220-48230
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The activation of OR51E1 causes growth suppression of human prostate cancer cells

The activation of OR51E1 causes growth suppression of human prostate cancer cells

https://doi.org/10.18632/oncotarget.10197

Désirée Maßberg, Nikolina Jovancevic, Anne Offermann, Annika Simon, Aria Baniahmad, Sven Perner, Thanakorn Pungsrinont, Katarina Luko, Stathis Philippou, Burkhard Ubrig, Markus Heiland, Lea Weber, Janine Altmüller, Christian Becker, Günter Gisselmann, Lian Gelis,  and Hanns Hatt
48231-48249
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SFMBT2 (Scm-like with four mbt domains 2) negatively regulates cell migration and invasion in prostate cancer cells

SFMBT2 (Scm-like with four mbt domains 2) negatively regulates cell migration and invasion in prostate cancer cells

https://doi.org/10.18632/oncotarget.10198

Jungsug Gwak, Jee Yoon Shin, Kwanghyun Lee, Soon Ki Hong, Sangtaek Oh, Sung-Ho Goh, Won Sun Kim,  and Bong Gun Ju
48250-48264
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The pancreatic niche inhibits the effectiveness of sunitinib treatment of pancreatic cancer

The pancreatic niche inhibits the effectiveness of sunitinib treatment of pancreatic cancer

https://doi.org/10.18632/oncotarget.10199

Neus Martínez-Bosch, Pedro Enrique Guerrero, Mireia Moreno, Anabel José, Mar Iglesias, Jessica Munné-Collado, Héctor Anta, Joan Gibert, Carlos Alberto Orozco, Judith Vinaixa, Cristina Fillat, Francesc Viñals,  and Pilar Navarro
48265-48279
Abstract  |  PDF  |  HTML  |  Order a Reprint

Pim kinase inhibition sensitizes FLT3-ITD acute myeloid leukemia cells to topoisomerase 2 inhibitors through increased DNA damage and oxidative stress

Pim kinase inhibition sensitizes FLT3-ITD acute myeloid leukemia cells to topoisomerase 2 inhibitors through increased DNA damage and oxidative stress

https://doi.org/10.18632/oncotarget.10209

Kshama A. Doshi, Rossana Trotta, Karthika Natarajan, Feyruz V. Rassool, Adriana E. Tron, Dennis Huszar, Danilo Perrotti,  and Maria R. Baer
48280-48295
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mesenchymal stem cells promote osteosarcoma cell survival and drug resistance through activation of STAT3

Mesenchymal stem cells promote osteosarcoma cell survival and drug resistance through activation of STAT3

https://doi.org/10.18632/oncotarget.10219

Bing Tu, Jing Zhu, Shen Liu, Lei Wang, Qiming Fan, Yongqiang Hao, Cunyi Fan,  and Ting-Ting Tang
48296-48308
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A p53-independent apoptotic mechanism of adenoviral mutant E1A was involved in its selective antitumor activity for human cancer

A p53-independent apoptotic mechanism of adenoviral mutant E1A was involved in its selective antitumor activity for human cancer

https://doi.org/10.18632/oncotarget.10221

Lin Fang, Qian Cheng, Jingjing Zhao, Yan Ge, Qi Zhu, Min Zhao, Jie Zhang, Qi Zhang, Liantao Li, Junjie Liu,  and Junnian Zheng
48309-48320
Abstract  |  PDF  |  HTML  |  Order a Reprint

miR-153-3p, a new bio-target, is involved in the pathogenesis of acute graft-versus-host disease via inhibition of indoleamine- 2,3-dioxygenase

miR-153-3p, a new bio-target, is involved in the pathogenesis of acute graft-versus-host disease via inhibition of indoleamine- 2,3-dioxygenase

https://doi.org/10.18632/oncotarget.10220

Xiao-su Zhao, Yi-nuo Wang, Meng Lv, Yuan Kong, Hong-xue Luo, Xiao-yang Ye, Qi Wu, Tong-feng Zhao, Yue-huan Hu, Hong-yu Zhang, Ming-rui Huo, Jun Wan,  and Xiao-jun Huang
48321-48334
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Blockade of the chemokine receptor, CCR5, reduces the growth of orthotopically injected colon cancer cells via limiting cancer-associated fibroblast accumulation

Blockade of the chemokine receptor, CCR5, reduces the growth of orthotopically injected colon cancer cells via limiting cancer-associated fibroblast accumulation

https://doi.org/10.18632/oncotarget.10227

Yamato Tanabe, Soichiro Sasaki, Naofumi Mukaida,  and Tomohisa Baba
48335-48345
Abstract  |  PDF  |  HTML  |  Order a Reprint

Aurora kinase A revives dormant laryngeal squamous cell carcinoma cells via FAK/PI3K/Akt pathway activation

Aurora kinase A revives dormant laryngeal squamous cell carcinoma cells via FAK/PI3K/Akt pathway activation

https://doi.org/10.18632/oncotarget.10233

Li-yun Yang, Chang-yu He, Xue-hua Chen, Li-ping Su, Bing-ya Liu,  and Hao Zhang
48346-48359
Abstract  |  PDF  |  HTML  |  Order a Reprint

PD1 blockade enhances cytotoxicity of in vitro expanded natural killer cells towards myeloma cells

PD1 blockade enhances cytotoxicity of in vitro expanded natural killer cells towards myeloma cells

https://doi.org/10.18632/oncotarget.10235

Yanan Guo, Xiaoli Feng, Yang Jiang, Xiaoyun Shi, Xiangling Xing, Xiaoli Liu, Nailin Li, Bengt Fadeel,  and Chengyun Zheng
48360-48374
Abstract  |  PDF  |  HTML  |  Order a Reprint

Significant benefits of adding neoadjuvant chemotherapy before concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma: a meta-analysis of randomized controlled trials

Significant benefits of adding neoadjuvant chemotherapy before concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma: a meta-analysis of randomized controlled trials

https://doi.org/10.18632/oncotarget.10237

Mengmeng Wang, Huimin Tian, Gang Li, Tingwen Ge, Yudi Liu, Jiuwei Cui,  and Fujun Han
48375-48390
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ubiquitin-specific protease 2 decreases p53-dependent apoptosis in cutaneous T-cell lymphoma

Ubiquitin-specific protease 2 decreases p53-dependent apoptosis in cutaneous T-cell lymphoma

https://doi.org/10.18632/oncotarget.10268

Tianling Wei, Edyta Biskup, Lise Mette Rahbek Gjerdrum, Omid Niazi, Niels Ødum,  and Robert Gniadecki
48391-48400
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Immunotherapy based on dendritic cells pulsed with CTPFoxM1 fusion protein protects against the development of hepatocellular carcinoma

Immunotherapy based on dendritic cells pulsed with CTPFoxM1 fusion protein protects against the development of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.10269

Huiting Su, Bing Li, Lan Zheng, Haixia Wang,  and Liping Zhang
48401-48411
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-106b~25 cluster is upregulated in relapsed MLL-rearranged pediatric acute myeloid leukemia

MicroRNA-106b~25 cluster is upregulated in relapsed MLL-rearranged pediatric acute myeloid leukemia

https://doi.org/10.18632/oncotarget.10270

Lonneke J. Verboon, Askar Obulkasim, Jasmijn D.E. de Rooij, Jenny E. Katsman-Kuipers, Edwin Sonneveld, André Baruchel, Jan Trka, Dirk Reinhardt, Rob Pieters, Jacqueline Cloos, Gertjan J.L. Kaspers, Jan-Henning Klusmann, Christian Michel Zwaan, Maarten Fornerod,  and Marry M. van den Heuvel-Eibrink
48412-48422
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-200b is a key regulator of tumor progression and metabolism targeting lactate dehydrogenase A in human malignant glioma

miR-200b is a key regulator of tumor progression and metabolism targeting lactate dehydrogenase A in human malignant glioma

https://doi.org/10.18632/oncotarget.10301

Su Hu, Qian Jiang, Dongdong Luo, Lei Zhao, Xin Fu, Yuqin Chen, Xue Song, Lihua Li, Hailin Zhao, Yingfang He,  and Biao Peng
48423-48431
Abstract  |  PDF  |  HTML  |  Order a Reprint

MiRNA-200a expression is inverse correlation with hepatocyte growth factor expression in stromal fibroblasts and its high expression predicts a good prognosis in patients with non-small cell lung cancer

MiRNA-200a expression is inverse correlation with hepatocyte growth factor expression in stromal fibroblasts and its high expression predicts a good prognosis in patients with non-small cell lung cancer

https://doi.org/10.18632/oncotarget.10302

Yongbing Chen, Menghua Du, Jin Wang, Pengfei Xing, Yongsheng Zhang, Feng Li,  and Xueguan Lu
48432-48442
Abstract  |  PDF  |  HTML  |  Order a Reprint

A classical PKA inhibitor increases the oncolytic effect of M1 virus via activation of exchange protein directly activated by cAMP 1

A classical PKA inhibitor increases the oncolytic effect of M1 virus via activation of exchange protein directly activated by cAMP 1

https://doi.org/10.18632/oncotarget.10305

Kai Li, Jiankai Liang, Yuan Lin, Haipeng Zhang, Xiao Xiao, Yaqian Tan, Jing Cai, Wenbo Zhu, Fan Xing, Jun Hu,  and Guangmei Yan
48443-48455
Abstract  |  PDF  |  HTML  |  Order a Reprint

IGF2-derived miR-483 mediated oncofunction by suppressing DLC-1 and associated with colorectal cancer

IGF2-derived miR-483 mediated oncofunction by suppressing DLC-1 and associated with colorectal cancer

https://doi.org/10.18632/oncotarget.10309

Hengmi Cui, Yuan Liu, Jingrui Jiang, Yangyang Liu, Zhe Yang, Shaogen Wu, Wangsen Cao, Isabelle H. Cui,  and Chenggong Yu
48456-48466
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The anti-tumor efficacy of 3-(2-Nitrophenyl) propionic acid-paclitaxel (NPPA-PTX): a novel paclitaxel bioreductive prodrug

The anti-tumor efficacy of 3-(2-Nitrophenyl) propionic acid-paclitaxel (NPPA-PTX): a novel paclitaxel bioreductive prodrug

https://doi.org/10.18632/oncotarget.10310

Ping Song, Xin Yao, Ting Zhong, Shuang Zhang, Yang Guo, Wei Ren, Dan Huang, Xiao-Chuan Duan, Yi-Fan Yin, Shu-Shi Zhang,  and Xuan Zhang
48467-48480
Abstract  |  PDF  |  HTML  |  Order a Reprint

EphrinA4 plays a critical role in α4 and αL mediated survival of human CLL cells during extravasation

EphrinA4 plays a critical role in α4 and αL mediated survival of human CLL cells during extravasation

https://doi.org/10.18632/oncotarget.10311

Miguel A. Flores, Paula Fortea, Eva M. Trinidad, Dolores García, Gloria Soler, Francisco J. Ortuño, Agustín G. Zapata,  and Luis M. Alonso-Colmenar
48481-48500
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of ERα/ERK/P62 cascades induces “autophagic switch” in the estrogen receptor-positive breast cancer cells exposed to gemcitabine

Inhibition of ERα/ERK/P62 cascades induces “autophagic switch” in the estrogen receptor-positive breast cancer cells exposed to gemcitabine

https://doi.org/10.18632/oncotarget.10363

Peng Shen, Ming Chen, Mengye He, Luoquan Chen, Yinjing Song, Peng Xiao, Xiaopeng Wan, Feng Dai, Ting Pan,  and Qingqing Wang
48501-48516
Abstract  |  PDF  |  HTML  |  Order a Reprint

Enhanced cytotoxicity of reovirus and radiotherapy in melanoma cells is mediated through increased viral replication and mitochondrial apoptotic signalling

Enhanced cytotoxicity of reovirus and radiotherapy in melanoma cells is mediated through increased viral replication and mitochondrial apoptotic signalling

https://doi.org/10.18632/oncotarget.10365

Gráinne McEntee, Joan N. Kyula, David Mansfield, Henry Smith, Michelle Wilkinson, Claire Gregory, Victoria Roulstone, Matt Coffey,  and Kevin J. Harrington
48517-48532
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ΔNp63 mediates cellular survival and metastasis in canine osteosarcoma

ΔNp63 mediates cellular survival and metastasis in canine osteosarcoma

https://doi.org/10.18632/oncotarget.10406

Maren Cam, Heather L. Gardner, Ryan D. Roberts, Joelle M. Fenger, Denis C. Guttridge, Cheryl A. London,  and Hakan Cam
48533-48546
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-130b, an onco-miRNA in bladder cancer, is directly regulated by NF-κB and sustains NF-κB activation by decreasing Cylindromatosis expression

miR-130b, an onco-miRNA in bladder cancer, is directly regulated by NF-κB and sustains NF-κB activation by decreasing Cylindromatosis expression

https://doi.org/10.18632/oncotarget.10423

Xiaolu Cui, Chuize Kong, Yuyan Zhu, Yu Zeng, Zhe Zhang, Xiankui Liu, Bo Zhan, Chiyuan Piao,  and Zhenming Jiang
48547-48561
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Integrated omics-analysis reveals Wnt-mediated NAD+ metabolic reprogramming in cancer stem-like cells

Integrated omics-analysis reveals Wnt-mediated NAD+ metabolic reprogramming in cancer stem-like cells

https://doi.org/10.18632/oncotarget.10432

Jueun Lee, Hyun Jung Kee, Soonki Min, Ki Cheong Park, Sunho Park, Tae Hyun Hwang, Do Hyun Ryu, Geum-Sook Hwang,  and Jae-Ho Cheong
48562-48576
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Paclitaxel is necessary for improved survival in epithelial ovarian cancers with homologous recombination gene mutations

Paclitaxel is necessary for improved survival in epithelial ovarian cancers with homologous recombination gene mutations

https://doi.org/10.18632/oncotarget.9373

Stephanie Jean, Jiaqi Li, Dionyssios Katsaros, Bradley Wubbenhorst, Kara N. Maxwell, Lauren Fishbein, Michael W. McLane, Chiara Benedetto, Emilie Marion Canuto, Nandita Mitra, Lin Zhang, Katherine L. Nathanson,  and Janos L. Tanyi
48577-48585
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Simultaneous multitarget radiotherapy using helical tomotherapy and its combination with sorafenib for pulmonary metastases from hepatocellular carcinoma

Simultaneous multitarget radiotherapy using helical tomotherapy and its combination with sorafenib for pulmonary metastases from hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9374

Taiwei Sun, Jian He, Shumin Zhang, Jing Sun, Mengsu Zeng,  and Zhaochong Zeng
48586-48599
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical value of fluorine-18 2-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography in penile cancer

Clinical value of fluorine-18 2-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography in penile cancer

https://doi.org/10.18632/oncotarget.9375

Sheng Zhang, Wenfeng Li,  and Fei Liang
48600-48606
Abstract  |  PDF  |  HTML  |  Order a Reprint

Epigallocatechin-3-gallate ameliorates radiation-induced acute skin damage in breast cancer patients undergoing adjuvant radiotherapy

Epigallocatechin-3-gallate ameliorates radiation-induced acute skin damage in breast cancer patients undergoing adjuvant radiotherapy

https://doi.org/10.18632/oncotarget.9495

Wanqi Zhu, Li Jia, Guanxuan Chen, Hanxi Zhao, Xiaorong Sun, Xiangjiao Meng, Xianguang Zhao, Ligang Xing, Jinming Yu,  and Meizhu Zheng
48607-48613
Abstract  |  PDF  |  HTML  |  Order a Reprint

Age-specific effects on the prognosis after surgery for gastric cancer: A SEER population-based analysis

Age-specific effects on the prognosis after surgery for gastric cancer: A SEER population-based analysis

https://doi.org/10.18632/oncotarget.9548

Peng Song, Lei Wu, Bo Jiang, Zhijian Liu, Ke Cao,  and Wenxian Guan
48614-48624
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reviews

Evaluation and consequences of heterogeneity in the circulating tumor cell compartment

Evaluation and consequences of heterogeneity in the circulating tumor cell compartment

https://doi.org/10.18632/oncotarget.8015

Anja Brouwer, Bram De Laere, Dieter Peeters, Marc Peeters, Roberto Salgado, Luc Dirix,  and Steven Van Laere
48625-48643
Abstract  |  PDF  |  HTML  |  Order a Reprint

Emerging therapeutic targets in esophageal adenocarcinoma

Emerging therapeutic targets in esophageal adenocarcinoma

https://doi.org/10.18632/oncotarget.8777

Puja Gaur, Clayton R. Hunt,  and Tej K. Pandita
48644-48655
Abstract  |  PDF  |  HTML  |  Order a Reprint

KIFC1: a promising chemotherapy target for cancer treatment?

KIFC1: a promising chemotherapy target for cancer treatment?

https://doi.org/10.18632/oncotarget.8799

Yu-Xi Xiao,  and Wan-Xi Yang
48656-48670
Abstract  |  PDF  |  HTML  |  Order a Reprint

Circulating adiponectin levels in various malignancies: an updated meta-analysis of 107 studies

Circulating adiponectin levels in various malignancies: an updated meta-analysis of 107 studies

https://doi.org/10.18632/oncotarget.8932

Tai Wei, Peng Ye, Xin Peng, Li-Ling Wu,  and Guang-Yan Yu
48671-48691
Abstract  |  PDF  |  HTML  |  Order a Reprint

Mantle cell lymphoma in the era of precision medicine-diagnosis, biomarkers and therapeutic agents

Mantle cell lymphoma in the era of precision medicine-diagnosis, biomarkers and therapeutic agents

https://doi.org/10.18632/oncotarget.8961

Arati A. Inamdar, Andre Goy, Nehad M. Ayoub, Christen Attia, Lucia Oton, Varun Taruvai, Mark Costales, Yu-Ting Lin, Andrew Pecora,  and K. Stephen Suh
48692-48731
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The insulin-like growth factor system in multiple myeloma: diagnostic and therapeutic potential

The insulin-like growth factor system in multiple myeloma: diagnostic and therapeutic potential

https://doi.org/10.18632/oncotarget.8982

Liesbeth Bieghs, Hans E. Johnsen, Ken Maes, Eline Menu, Els Van Valckenborgh, Michael T. Overgaard, Mette Nyegaard, Cheryl A. Conover, Karin Vanderkerken,  and Elke De Bruyne
48732-48752
Abstract  |  PDF  |  HTML  |  Order a Reprint

Optical imaging probes in oncology

Optical imaging probes in oncology

https://doi.org/10.18632/oncotarget.9066

Cristina Martelli, Alessia Lo Dico, Cecilia Diceglie, Giovanni Lucignani,  and Luisa Ottobrini
48753-48787
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeted inhibition of STATs and IRFs as a potential treatment strategy in cardiovascular disease

Targeted inhibition of STATs and IRFs as a potential treatment strategy in cardiovascular disease

https://doi.org/10.18632/oncotarget.9195

Malgorzata Szelag, Anna Piaszyk-Borychowska, Martyna Plens-Galaska, Joanna Wesoly,  and Hans A.R. Bluyssen
48788-48812
Abstract  |  PDF  |  HTML  |  Order a Reprint

Physiological and pathological implications of 5-hydroxymethylcytosine in diseases

Physiological and pathological implications of 5-hydroxymethylcytosine in diseases

https://doi.org/10.18632/oncotarget.9281

Jing Liang, Fan Yang, Liang Zhao, Chongwei Bi,  and Benzhi Cai
48813-48831
Abstract  |  PDF  |  HTML  |  Order a Reprint

Circulating tumor DNA: a promising biomarker in the liquid biopsy of cancer

Circulating tumor DNA: a promising biomarker in the liquid biopsy of cancer

https://doi.org/10.18632/oncotarget.9453

Feifei Cheng, Li Su,  and Cheng Qian
48832-48841
Abstract  |  PDF  |  HTML  |  Order a Reprint

Case Reports

Exploration of the recurrence in radiation brain necrosis after bevacizumab discontinuation

Exploration of the recurrence in radiation brain necrosis after bevacizumab discontinuation

https://doi.org/10.18632/oncotarget.7768

Hongqing Zhuang, Xiangkun Yuan, Joe Y. Chang, Yongchun Song, Junjie Wang, Zhiyong Yuan, Xiaoguang Wang,  and Ping Wang
48842-48849
Abstract  |  PDF  |  HTML  |  Order a Reprint

Corrections

Correction: Validation of a preclinical model for assessment of drug efficacy in melanoma

Correction: Validation of a preclinical model for assessment of drug efficacy in melanoma

https://doi.org/10.18632/oncotarget.10822

Julie Delyon, Mariana Varna, Jean-Paul Feugeas, Aurélie Sadoux, Saliha Yahiaoui, Marie-Pierre Podgorniak, Geoffroy Leclert, Sarra Mazouz Dorval, Nicolas Dumaz, Anne Janin, Samia Mourah,  and Céleste Lebbé
48850
Correction  |  PDF

Retraction

Retraction: MMP-13 is involved in oral cancer cell metastasis

Retraction: MMP-13 is involved in oral cancer cell metastasis

https://doi.org/10.18632/oncotarget.10823

Shun-Hong Huang, Ching-Hsuan Law, Ping-Hsueh Kuo, Ren-Yu Hu, Ching-Chieh Yang, Ting-Wen Chung, Ji-Min Li, Li-Hsun Lin, Yi-Chung Liu, En-Chi Liao, Yi-Ting Tsai, Yu-Shan Wei, Chi-Chen Lin, Chien-Wen Chang, Hsiu-Chuan Chou, Wen-Ching Wang, Margaret Dah-Tsyr Chang, Lu-Hai Wang, Hsing-Jien Kung, Hong-Lin Chan,  and Ping-Chiang Lyu
48851
Retraction  |  PDF


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