Oncotarget

Vol 7, No 29

July 19, 2016

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Female AagTg/Parp1-/- mice are protected from MMS-mediated kidney damage. See Calvo et al.

Table of Contents

Editorial

TNF-driven cell fate: till HACE do us part

TNF-driven cell fate: till HACE do us part

https://doi.org/10.18632/oncotarget.10168

Luigi Tortola, Roberto Nitsch,  and Josef M. Penninger
44871-44872
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mTOR: Alzheimer’s disease prevention for APOE4 carriers

mTOR: Alzheimer’s disease prevention for APOE4 carriers

https://doi.org/10.18632/oncotarget.10349

Ai-Ling Lin, David Allan Butterfield,  and Arlan Richardson
44873-44874
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Arenaviral vaccine vectors to combat infectious diseases

Arenaviral vaccine vectors to combat infectious diseases

https://doi.org/10.18632/oncotarget.10405

Rekha Dhanwani,  and Hinh Ly
44875-44875
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Research Perspectives

Rapamycin in aging and disease: maximizing efficacy while minimizing side effects

Rapamycin in aging and disease: maximizing efficacy while minimizing side effects

https://doi.org/10.18632/oncotarget.10381

Simon C. Johnson,  and Matt Kaeberlein
44876-44878
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Research Papers: Gerotarget (Focus on Aging)

Mitochondrial dysfunction and oxidative stress in aging and cancer

Mitochondrial dysfunction and oxidative stress in aging and cancer

https://doi.org/10.18632/oncotarget.9821

Anna V. Kudryavtseva, George S. Krasnov, Alexey A. Dmitriev, Boris Y. Alekseev, Olga L. Kardymon, Asiya F. Sadritdinova, Maria S. Fedorova, Anatoly V. Pokrovsky, Nataliya V. Melnikova, Andrey D. Kaprin, Alexey A. Moskalev,  and Anastasiya V. Snezhkina
44879-44905
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Vδ2+ and α/ß T cells show divergent trajectories during human aging

Vδ2+ and α/ß T cells show divergent trajectories during human aging

https://doi.org/10.18632/oncotarget.10096

Crystal Tze Ying Tan, Kilian Wistuba-Hamprecht, Weili Xu, Ma Schwe Zin Nyunt, Anusha Vasudev, Bernett Teck Kwong Lee, Graham Pawelec, Kia Joo Puan, Olaf Rotzschke, Tze Pin Ng,  and Anis Larbi
44906-44918
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Platelets as an indicator of vascular repair in elderly Japanese men

Platelets as an indicator of vascular repair in elderly Japanese men

https://doi.org/10.18632/oncotarget.10229

Yuji Shimizu, Shimpei Sato, Jun Koyamatsu, Hirotomo Yamanashi, Mako Nagayoshi, Koichiro Kadota,  and Takahiro Maeda
44919-44926
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Research Papers: Pathology

β-cell insulin receptor deficiency during in utero development induces an islet compensatory overgrowth response

β-cell insulin receptor deficiency during in utero development induces an islet compensatory overgrowth response

https://doi.org/10.18632/oncotarget.10342

Mark Trinder, Liangyi Zhou, Amanda Oakie, Matthew Riopel,  and Rennian Wang
44927-44940
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EPCs enhance angiogenesis in renal regeneration

EPCs enhance angiogenesis in renal regeneration

https://doi.org/10.18632/oncotarget.10377

Xin Wang, Yaling Yu, Miaozhong Li, Ali Alkhawaji, Chuan Chen, Xiaolin Liu, Junqun Jiang, Jianse Zhang, Zhibin Wang, Ting Li, Weiwen Zhang,  and Jin Mei
44941-44949
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Parp1 protects against Aag-dependent alkylation-induced nephrotoxicity in a sex-dependent manner

Parp1 protects against Aag-dependent alkylation-induced nephrotoxicity in a sex-dependent manner

https://doi.org/10.18632/oncotarget.10440

Jennifer A. Calvo, Mariacarmela Allocca, Kimberly R. Fake, Sureshkumar Muthupalani, Joshua J. Corrigan, Roderick T. Bronson,  and Leona D. Samson
44950-44965
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Research Papers: Immunology

Altered calcium influx of peripheral Th2 cells in pediatric Crohn’s disease: infliximab may normalize activation patterns

Altered calcium influx of peripheral Th2 cells in pediatric Crohn’s disease: infliximab may normalize activation patterns

https://doi.org/10.18632/oncotarget.10036

Csaba Orbán, Dolóresz Szabó, Anna Bajnok, Barna Vásárhelyi, Tivadar Tulassay, András Arató, Gábor Veres,  and Gergely Toldi
44966-44974
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Discoidin domain receptor 1 promotes Th17 cell migration by activating the RhoA/ROCK/MAPK/ERK signaling pathway

Discoidin domain receptor 1 promotes Th17 cell migration by activating the RhoA/ROCK/MAPK/ERK signaling pathway

https://doi.org/10.18632/oncotarget.10455

Mohammed-Amine El Azreq, Maleck Kadiri, Marc Boisvert, Nathalie Pagé, Philippe A. Tessier,  and Fawzi Aoudjit
44975-44990
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Research Papers: Neuroscience

Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy

Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy

https://doi.org/10.18632/oncotarget.10449

Reinier Oropesa-Nuñez, Silvia Seghezza, Silvia Dante, Alberto Diaspro, Roberta Cascella, Cristina Cecchi, Massimo Stefani, Fabrizio Chiti,  and Claudio Canale
44991-45004
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Research Papers

Phosphohistone H3 (pHH3) is a prognostic and epithelial to mesenchymal transition marker in diffuse gliomas

Phosphohistone H3 (pHH3) is a prognostic and epithelial to mesenchymal transition marker in diffuse gliomas

https://doi.org/10.18632/oncotarget.7154

Ping Zhu, Chuan-Bao Zhang, Pei Yang, Jing Chen, Yu-Qing Liu, Hui-Min Hu, Hua Huang, Zhao-Shi Bao, Wei Zhang, Wei-Jia Kong,  and Tao Jiang
45005-45014
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Sunitinib-induced morpho-functional changes and drug effectiveness in malignant solitary fibrous tumours

Sunitinib-induced morpho-functional changes and drug effectiveness in malignant solitary fibrous tumours

https://doi.org/10.18632/oncotarget.7523

Rosalin D. Spagnuolo, Silvia Brich, Fabio Bozzi, Elena Conca, Chiara Castelli, Marcella Tazzari, Roberta Maestro, Monica Brenca, Ambra V. Gualeni, Annunziata Gloghini, Silvia Stacchiotti, Marco A. Pierotti, Silvana Pilotti,  and Tiziana Negri
45015-45026
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Identification and characterization of lncRNA mediated transcriptional dysregulation dictates lncRNA roles in glioblastoma

Identification and characterization of lncRNA mediated transcriptional dysregulation dictates lncRNA roles in glioblastoma

https://doi.org/10.18632/oncotarget.7801

Yongsheng Li, Zishan Wang, Yuan Wang, Zheng Zhao, Jinwen Zhang, Jianping Lu, Juan Xu,  and Xia Li
45027-45041
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Neuregulin expression in solid tumors: Prognostic value and predictive role to anti-HER3 therapies

Neuregulin expression in solid tumors: Prognostic value and predictive role to anti-HER3 therapies

https://doi.org/10.18632/oncotarget.8648

Alberto Ocaña, Laura Díez-González, Azucena Esparís-Ogando, Juan Carlos Montero, Eitan Amir,  and Atanasio Pandiella
45042-45051
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LTBP2 is a prognostic marker in head and neck squamous cell carcinoma

LTBP2 is a prognostic marker in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.8855

Liang Han, Ming ming Tang, Xinjiang Xu, Bin Jiang, Jianfei Huang, Xingmei Feng,  and Jianfeng Qiang
45052-45059
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C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mechanisms

C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mechanisms

https://doi.org/10.18632/oncotarget.9911

Neibla Priego, María Arechederra, Celia Sequera, Paloma Bragado, Ana Vázquez-Carballo, Álvaro Gutiérrez-Uzquiza, Víctor Martín-Granado, Juan José Ventura, Marcelo G. Kazanietz, Carmen Guerrero,  and Almudena Porras
45060-45078
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting cancer stem cells with p53 modulators

Targeting cancer stem cells with p53 modulators

https://doi.org/10.18632/oncotarget.8650

Zhan Zhang, Ling Liu, Roberto Gomez-Casal, Xinhui Wang, Ryo Hayashi, Ettore Appella, Levy Kopelovich,  and Albert B. DeLeo
45079-45093
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Quantitative ultrasound assessment of breast tumor response to chemotherapy using a multi-parameter approach

Quantitative ultrasound assessment of breast tumor response to chemotherapy using a multi-parameter approach

https://doi.org/10.18632/oncotarget.8862

Hadi Tadayyon, Lakshmanan Sannachi, Mehrdad Gangeh, Ali Sadeghi-Naini, William Tran, Maureen E. Trudeau, Kathleen Pritchard, Sonal Ghandi, Sunil Verma,  and Gregory J. Czarnota
45094-45111
Abstract  |  PDF  |  HTML  |  Order a Reprint

Enhanced autophagy in colorectal cancer stem cells does not contribute to radio-resistance

Enhanced autophagy in colorectal cancer stem cells does not contribute to radio-resistance

https://doi.org/10.18632/oncotarget.8972

Chen Yan, Lan Luo, Shinji Goto, Yoshishige Urata, Chang-Ying Guo, Hanako Doi, Kaio Kitazato,  and Tao-Sheng Li
45112-45121
Abstract  |  PDF  |  HTML  |  Order a Reprint

Radiosensitization of HNSCC cells by EGFR inhibition depends on the induction of cell cycle arrests

Radiosensitization of HNSCC cells by EGFR inhibition depends on the induction of cell cycle arrests

https://doi.org/10.18632/oncotarget.9161

Malte Kriegs, Ulla Kasten-Pisula, Britta Riepen, Konstantin Hoffer, Nina Struve, Laura Myllynen, Friederike Braig, Mascha Binder, Thorsten Rieckmann, Reidar Grénman, Cordula Petersen, Ekkehard Dikomey,  and Kai Rothkamm
45122-45133
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

EZH2 promotes metabolic reprogramming in glioblastomas through epigenetic repression of EAF2-HIF1α signaling

EZH2 promotes metabolic reprogramming in glioblastomas through epigenetic repression of EAF2-HIF1α signaling

https://doi.org/10.18632/oncotarget.9761

Bo Pang, Xiang-Rong Zheng, Jing-xia Tian, Tai-hong Gao, Guang-yan Gu, Rui Zhang, Yi-Bing Fu, Qi Pang, Xin-Gang Li,  and Qian Liu
45134-45143
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

DLC1 is the principal biologically-relevant down-regulated DLC family member in several cancers

DLC1 is the principal biologically-relevant down-regulated DLC family member in several cancers

https://doi.org/10.18632/oncotarget.9266

Dunrui Wang, Xiaolan Qian, Megha Rajaram, Marian E. Durkin,  and Douglas R. Lowy
45144-45157
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel anticancer agent SNG1153 inhibits growth of lung cancer stem/progenitor cells

A novel anticancer agent SNG1153 inhibits growth of lung cancer stem/progenitor cells

https://doi.org/10.18632/oncotarget.9783

Shiyang Liu, Yuming Guo, Jing Wang, Hai Zhu, Yuqing Han, Mingji Jin, Jun Wang, Congya Zhou, Junfeng Ma, Qingcong Lin, Zhaoyi Wang, Kun Meng,  and Xueqi Fu
45158-45170
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GRK3 is a direct target of CREB activation and regulates neuroendocrine differentiation of prostate cancer cells

GRK3 is a direct target of CREB activation and regulates neuroendocrine differentiation of prostate cancer cells

https://doi.org/10.18632/oncotarget.9359

Meixiang Sang, Mohit Hulsurkar, Xiaochong Zhang, Haiping Song, Dayong Zheng, Yan Zhang, Min Li, Jianming Xu, Songlin Zhang, Michael Ittmann,  and Wenliang Li
45171-45185
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HER2 reduces breast cancer radiosensitivity by activating focal adhesion kinase in vitro and in vivo

HER2 reduces breast cancer radiosensitivity by activating focal adhesion kinase in vitro and in vivo

https://doi.org/10.18632/oncotarget.9870

Jing Hou, Zhirui Zhou, Xingxing Chen, Ruping Zhao, Zhaozhi Yang, Na Wei, Qing Ni, Yan Feng, Xiaoli Yu, Jinli Ma,  and Xiaomao Guo
45186-45198
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-20a-5p promotes colorectal cancer invasion and metastasis by downregulating Smad4

MicroRNA-20a-5p promotes colorectal cancer invasion and metastasis by downregulating Smad4

https://doi.org/10.18632/oncotarget.9900

Dantong Cheng, Senlin Zhao, Huamei Tang, Dongyuan Zhang, Hongcheng Sun, Fudong Yu, Weiliang Jiang, Ben Yue, Jingtao Wang, Meng Zhang, Yang Yu, Xisheng Liu, Xiaofeng Sun, Zongguang Zhou, Xuebin Qin, Xin Zhang, Dongwang Yan, Yugang Wen,  and Zhihai Peng
45199-45213
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cyclin D1 unbalances the redox status controlling cell adhesion, migration, and drug resistance in myeloma cells

Cyclin D1 unbalances the redox status controlling cell adhesion, migration, and drug resistance in myeloma cells

https://doi.org/10.18632/oncotarget.9901

Sophie Bustany, Jérôme Bourgeais, Guergana Tchakarska, Simon Body, Olivier Hérault, Fabrice Gouilleux,  and Brigitte Sola
45214-45224
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Recurrence pattern and TP53 mutation in upper urinary tract urothelial carcinoma

Recurrence pattern and TP53 mutation in upper urinary tract urothelial carcinoma

https://doi.org/10.18632/oncotarget.9904

Chung-Hsin Chen, Kathleen G. Dickman, Chao-Yuan Huang, Chia-Tung Shun, Huai-Ching Tai, Kuo-How Huang, Shuo-Meng Wang, Yuan-Ju Lee, Arthur P. Grollman,  and Yeong-Shiau Pu
45225-45236
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Heterogeneity of resistance mutations detectable by next-generation sequencing in TKI-treated lung adenocarcinoma

Heterogeneity of resistance mutations detectable by next-generation sequencing in TKI-treated lung adenocarcinoma

https://doi.org/10.18632/oncotarget.9931

Deborah A. Belchis, Li-Hui Tseng, Thomas Gniadek, Lisa Haley, Parvez Lokhandwala, Peter Illei, Christopher D. Gocke, Patrick Forde, Julie Brahmer, Frederic B. Askin, James R. Eshleman,  and Ming-Tseh Lin
45237-45248
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibiting cytoplasmic accumulation of HuR synergizes genotoxic agents in urothelial carcinoma of the bladder

Inhibiting cytoplasmic accumulation of HuR synergizes genotoxic agents in urothelial carcinoma of the bladder

https://doi.org/10.18632/oncotarget.9932

Jiawei Guo, Jing Lv, Siyu Chang, Zhi Chen, Weiqiang Lu, Chuanliang Xu, Mingyao Liu,  and Xiufeng Pang
45249-45262
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MLN4924 suppresses neddylation and induces cell cycle arrest, senescence, and apoptosis in human osteosarcoma

MLN4924 suppresses neddylation and induces cell cycle arrest, senescence, and apoptosis in human osteosarcoma

https://doi.org/10.18632/oncotarget.9481

Yi Zhang, Cheng-Cheng Shi, Hua-Peng Zhang, Gong-Quan Li,  and Shan-Shan Li
45263-45274
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel approach to inoperable or recurrent rectal cancer by chemoembolization. A new arrow in our quiver?

A novel approach to inoperable or recurrent rectal cancer by chemoembolization. A new arrow in our quiver?

https://doi.org/10.18632/oncotarget.9940

Roberto Bini, Simone Comelli, Renzo Leli, Giacomo Paolo Vaudano, Daniele Savio, Tiziana Viora,  and Alfredo Addeo
45275-45282
Abstract  |  PDF  |  HTML  |  Order a Reprint

Neutrophil-to-lymphocyte ratio for the prognostic assessment of hepatocellular carcinoma: A systematic review and meta-analysis of observational studies

Neutrophil-to-lymphocyte ratio for the prognostic assessment of hepatocellular carcinoma: A systematic review and meta-analysis of observational studies

https://doi.org/10.18632/oncotarget.9942

Xingshun Qi, Jianjun Li, Han Deng, Hongyu Li, Chunping Su,  and Xiaozhong Guo
45283-45301
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

EGR1 mediates miR-203a suppress the hepatocellular carcinoma cells progression by targeting HOXD3 through EGFR signaling pathway

EGR1 mediates miR-203a suppress the hepatocellular carcinoma cells progression by targeting HOXD3 through EGFR signaling pathway

https://doi.org/10.18632/oncotarget.9605

Lumin Wang, Hongfei Sun, Xiaofei Wang, Ni Hou, Lingyu Zhao, Dongdong Tong, Kang He, Yang Yang, Tusheng Song, Jun Yang,  and Chen Huang
45302-45316
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Proliferation and ovarian hormone signaling are impaired in normal breast tissues from women with BRCA1 mutations: benefit of a progesterone receptor modulator treatment as a breast cancer preventive strategy in women with inherited BRCA1 mutations

Proliferation and ovarian hormone signaling are impaired in normal breast tissues from women with BRCA1 mutations: benefit of a progesterone receptor modulator treatment as a breast cancer preventive strategy in women with inherited BRCA1 mutations

https://doi.org/10.18632/oncotarget.9638

Laudine Communal, Myriam Vilasco, Justine Hugon-Rodin, Aurélie Courtin, Najat Mourra, Najiba Lahlou, Morwenna Le Guillou, Muriel Perrault de Jotemps, Marie-Pierre Chauvet, Marc Chaouat, Pascal Pujol, Jean Feunteun, Suzette Delaloge, Patricia Forgez,  and Anne Gompel
45317-45330
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Role of FOXO1 in aldosterone-induced autophagy: A compensatory protective mechanism related to podocyte injury

Role of FOXO1 in aldosterone-induced autophagy: A compensatory protective mechanism related to podocyte injury

https://doi.org/10.18632/oncotarget.9644

Bin Wang, Wei Ding, Minmin Zhang, Hongmei Li, Honglei Guo, Lilu Lin, Jing Chen,  and Yong Gu
45331-45351
Abstract  |  PDF  |  HTML  |  Order a Reprint

PRAME expression and promoter hypomethylation in epithelial ovarian cancer

PRAME expression and promoter hypomethylation in epithelial ovarian cancer

https://doi.org/10.18632/oncotarget.9977

Wa Zhang, Carter J. Barger, Kevin H. Eng, David Klinkebiel, Petra A. Link, Angela Omilian, Wiam Bshara, Kunle Odunsi,  and Adam R. Karpf
45352-45369
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The tumor suppressor miR-138-5p targets PD-L1 in colorectal cancer

The tumor suppressor miR-138-5p targets PD-L1 in colorectal cancer

https://doi.org/10.18632/oncotarget.9659

Lian Zhao, Haibo Yu, Shuijing Yi, Xiaowei Peng, Peng Su, Zhiming Xiao, Rui Liu, Anliu Tang, Xiayu Li, Fen Liu,  and Shourong Shen
45370-45384
Abstract  |  PDF  |  HTML  |  Order a Reprint

Role of microRNA-4516 involved autophagy associated with exposure to fine particulate matter

Role of microRNA-4516 involved autophagy associated with exposure to fine particulate matter

https://doi.org/10.18632/oncotarget.9978

Xiaobo Li, Yang Lv, Jihong Hao, Hao Sun, Na Gao, Chengcheng Zhang, Runze Lu, Shizhi Wang, Lihong Yin, Yuepu Pu,  and Rui Chen
45385-45397
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Deregulation of polycomb repressor complex 1 modifier AUTS2 in T-cell leukemia

Deregulation of polycomb repressor complex 1 modifier AUTS2 in T-cell leukemia

https://doi.org/10.18632/oncotarget.9982

Stefan Nagel, Claudia Pommerenke, Corinna Meyer, Maren Kaufmann, Hans G. Drexler,  and Roderick A.F. MacLeod
45398-45413
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Giant obscurins regulate the PI3K cascade in breast epithelial cells via direct binding to the PI3K/p85 regulatory subunit

Giant obscurins regulate the PI3K cascade in breast epithelial cells via direct binding to the PI3K/p85 regulatory subunit

https://doi.org/10.18632/oncotarget.9985

Marey Shriver, Saravanakumar Marimuthu, Colin Paul, Janelle Geist, Tessa Seale, Konstantinos Konstantopoulos,  and Aikaterini Kontrogianni- Konstantopoulos
45414-45428
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The isopeptidase inhibitor 2cPE triggers proteotoxic stress and ATM activation in chronic lymphocytic leukemia cells

The isopeptidase inhibitor 2cPE triggers proteotoxic stress and ATM activation in chronic lymphocytic leukemia cells

https://doi.org/10.18632/oncotarget.9742

Andrea Tomasella, Raffaella Picco, Sonia Ciotti, Andrea Sgorbissa, Elisa Bianchi, Rossella Manfredini, Fabio Benedetti, Valentina Trimarco, Federica Frezzato, Livio Trentin, Gianpietro Semenzato, Domenico Delia,  and Claudio Brancolini
45429-45443
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Analysis of clock gene-miRNA correlation networks reveals candidate drivers in colorectal cancer

Analysis of clock gene-miRNA correlation networks reveals candidate drivers in colorectal cancer

https://doi.org/10.18632/oncotarget.9989

Gianluigi Mazzoccoli, Tommaso Colangelo, Anna Panza, Rosa Rubino, Cristiana Tiberio, Orazio Palumbo, Massimo Carella, Domenico Trombetta, Annamaria Gentile, Francesca Tavano, Maria Rosa Valvano, Clelia Tiziana Storlazzi, Gemma Macchia, Angelo De Cata, Giovanni Bisceglia, Daniele Capocefalo, Vittorio Colantuoni, Lina Sabatino, Ada Piepoli,  and Tommaso Mazza
45444-45461
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gastrin-induced miR-222 promotes gastric tumor development by suppressing p27kip1

Gastrin-induced miR-222 promotes gastric tumor development by suppressing p27kip1

https://doi.org/10.18632/oncotarget.9990

Katie A. Lloyd, Andrew R. Moore, Bryony N. Parsons, Adrian O’Hara, Malcolm Boyce, Graham J. Dockray, Andrea Varro,  and D. Mark Pritchard
45462-45478
Abstract  |  PDF  |  HTML  |  Order a Reprint

Single, immediate postoperative instillation of chemotherapy in non-muscle invasive bladder cancer: a systematic review and network meta-analysis of randomized clinical trials using different drugs

Single, immediate postoperative instillation of chemotherapy in non-muscle invasive bladder cancer: a systematic review and network meta-analysis of randomized clinical trials using different drugs

https://doi.org/10.18632/oncotarget.9991

Minyong Kang, Chang Wook Jeong, Cheol Kwak, Hyeon Hoe Kim,  and Ja Hyeon Ku
45479-45488
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Quercetin induces cell apoptosis of myeloma and displays a synergistic effect with dexamethasone in vitro and in vivo xenograft models

Quercetin induces cell apoptosis of myeloma and displays a synergistic effect with dexamethasone in vitro and in vivo xenograft models

https://doi.org/10.18632/oncotarget.9993

Donghua He, Xing Guo, Enfan Zhang, Fuming Zi, Jing Chen, Qingxiao Chen, Xuanru Lin, Li Yang, Yi Li, Wenjun Wu, Yang Yang, Jingsong He,  and Zhen Cai
45489-45499
Abstract  |  PDF  |  HTML  |  Order a Reprint

The HIV-derived protein Vpr52-96 has anti-glioma activity in vitro and in vivo

The HIV-derived protein Vpr52-96 has anti-glioma activity in vitro and in vivo

https://doi.org/10.18632/oncotarget.9787

Jens Kübler, Stefanie Kirschner, Linda Hartmann, Grit Welzel, Maren Engelhardt, Carsten Herskind, Marlon R. Veldwijk, Christian Schultz, Manuela Felix, Gerhard Glatting, Patrick Maier, Frederik Wenz, Marc A. Brockmann,  and Frank A. Giordano
45500-45512
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Fluorouracil-based neoadjuvant chemoradiotherapy with or without oxaliplatin for treatment of locally advanced rectal cancer: An updated systematic review and meta-analysis

Fluorouracil-based neoadjuvant chemoradiotherapy with or without oxaliplatin for treatment of locally advanced rectal cancer: An updated systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.9995

Yong-Jing Yang, Ling Cao, Zhi-Wen Li, Ling Zhao, Hong-Fen Wu, Dan Yue, Jin-Lei Yang, Zhi-Rui Zhou,  and Shi-Xin Liu
45513-45524
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

C-met inhibition blocks bone metastasis development induced by renal cancer stem cells

C-met inhibition blocks bone metastasis development induced by renal cancer stem cells

https://doi.org/10.18632/oncotarget.9997

Lucia D'Amico, Dimas Belisario, Giorgia Migliardi, Cristina Grange, Benedetta Bussolati, Patrizia D'Amelio, Timothy Perera, Ettore Dalmasso, Luca Dalle Carbonare, Laura Godio, Paolo Comoglio, Livio Trusolino, Riccardo Ferracini,  and Ilaria Roato
45525-45537
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic significance of CD44 in human colon cancer and gastric cancer: Evidence from bioinformatic analyses

Prognostic significance of CD44 in human colon cancer and gastric cancer: Evidence from bioinformatic analyses

https://doi.org/10.18632/oncotarget.9998

Pu Xia,  and Xiao-Yan Xu
45538-45546
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-1291 targets the FOXA2-AGR2 pathway to suppress pancreatic cancer cell proliferation and tumorigenesis

MicroRNA-1291 targets the FOXA2-AGR2 pathway to suppress pancreatic cancer cell proliferation and tumorigenesis

https://doi.org/10.18632/oncotarget.9999

Mei-Juan Tu, Yu-Zhuo Pan, Jing-Xin Qiu, Edward J. Kim,  and Ai-Ming Yu
45547-45561
Abstract  |  PDF  |  HTML  |  Order a Reprint

Discovery and characterization of a novel potent type II native and mutant BCR-ABL inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML)

Discovery and characterization of a novel potent type II native and mutant BCR-ABL inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML)

https://doi.org/10.18632/oncotarget.10037

Feiyang Liu, Beilei Wang, Qiang Wang, Ziping Qi, Cheng Chen, Lu-Lu Kong, Ji-Yun Chen, Xiaochuan Liu, Aoli Wang, Chen Hu, Wenchao Wang, Huiping Wang, Fan Wu, Yanjie Ruan, Shuang Qi, Juan Liu, Fengming Zou, Zhenquan Hu, Wei Wang, Li Wang, Shanchun Zhang, Cai-Hong Yun, Zhimin Zhai, Jing Liu,  and Qingsong Liu
45562-45574
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression of functional neuronal receptor latrophilin 1 in human acute myeloid leukaemia cells

Expression of functional neuronal receptor latrophilin 1 in human acute myeloid leukaemia cells

https://doi.org/10.18632/oncotarget.10039

Vadim V. Sumbayev, Isabel Gonçalves Silva, Jennifer Blackburn, Bernhard F. Gibbs, Inna M. Yasinska, Michelle D. Garrett, Alexander G. Tonevitsky,  and Yuri A. Ushkaryov
45575-45583
Abstract  |  PDF  |  HTML  |  Order a Reprint

Network-based identification of microRNAs as potential pharmacogenomic biomarkers for anticancer drugs

Network-based identification of microRNAs as potential pharmacogenomic biomarkers for anticancer drugs

https://doi.org/10.18632/oncotarget.10052

Jie Li, Kecheng Lei, Zengrui Wu, Weihua Li, Guixia Liu, Jianwen Liu, Feixiong Cheng,  and Yun Tang
45584-45596
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein

The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein

https://doi.org/10.18632/oncotarget.10056

Lavoisier Ramos-Espiritu, Ana Diaz, Charlee Nardin, Anthony J. Saviola, Fiona Shaw, Tamar Plitt, Xia Yang, Jedd Wolchok, Edyta C. Pirog, Garrett Desman, Andrea Sboner, Tuo Zhang, Jenny Xiang, Taha Merghoub, Lonny R. Levin, Jochen Buck,  and Jonathan H. Zippin
45597-45607
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

KLF4α stimulates breast cancer cell proliferation by acting as a KLF4 antagonist

KLF4α stimulates breast cancer cell proliferation by acting as a KLF4 antagonist

https://doi.org/10.18632/oncotarget.10058

Jacqueline Ferralli, Ruth Chiquet-Ehrismann,  and Martin Degen
45608-45621
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-218 inhibits EMT, migration and invasion by targeting SFMBT1 and DCUN1D1 in cervical cancer

MicroRNA-218 inhibits EMT, migration and invasion by targeting SFMBT1 and DCUN1D1 in cervical cancer

https://doi.org/10.18632/oncotarget.9850

Zhaojing Jiang, Qiancheng Song, Rong Zeng, Jing Li, Jingyu Li, Xiaochun Lin, Xing Chen, Jiren Zhang,  and Yanfang Zheng
45622-45636
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Serum microRNA profiles as prognostic biomarkers for HBV-positive hepatocellular carcinoma

Serum microRNA profiles as prognostic biomarkers for HBV-positive hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.10082

Hao-Tu Zhu, Abdulbaqi M. E. Hasan, Rong-Bin Liu, Zi-Chen Zhang, Xiao Zhang, Jing Wang, Hai-Yun Wang, Fang Wang,  and Jian-Yong Shao
45637-45648
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Heterogeneity of metastatic pancreatic adenocarcinoma: Lung metastasis show better prognosis than liver metastasis—a case control study

Heterogeneity of metastatic pancreatic adenocarcinoma: Lung metastasis show better prognosis than liver metastasis—a case control study

https://doi.org/10.18632/oncotarget.9861

Claire Decoster, Marine Gilabert, Aurélie Autret, Olivier Turrini, Sandrine Oziel-Taieb, Flora Poizat, Marc Giovannini, Patrice Viens, Juan Iovanna,  and Jean-Luc Raoul
45649-45655
Abstract  |  PDF  |  HTML  |  Order a Reprint

Extremely stringent activation of p16INK4a prevents immortalization of uterine cervical epithelial cells without human papillomavirus oncogene expression

Extremely stringent activation of p16INK4a prevents immortalization of uterine cervical epithelial cells without human papillomavirus oncogene expression

https://doi.org/10.18632/oncotarget.10120

Su Hang, Agnes F.Y. Tiwari, Hextan Y.S. Ngan, Yim-Ling Yip, Annie L.M. Cheung, Sai Wah Tsao,  and Wen Deng
45656-45670
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic role of sentinel lymph node biopsy for patients with cutaneous melanoma: A retrospective study of surveillance, epidemiology, and end-result population-based data

Prognostic role of sentinel lymph node biopsy for patients with cutaneous melanoma: A retrospective study of surveillance, epidemiology, and end-result population-based data

https://doi.org/10.18632/oncotarget.10140

Jie Chen, Yu Xu, Ye Zhou, Yanong Wang, Huiyan Zhu,  and Yingqiang Shi
45671-45677
Abstract  |  PDF  |  HTML  |  Order a Reprint

IL-35 expression in hepatocellular carcinoma cells is associated with tumor progression

IL-35 expression in hepatocellular carcinoma cells is associated with tumor progression

https://doi.org/10.18632/oncotarget.10141

Jun Long, Hongyan Guo, Shichang Cui, Haiyan Zhang, Xinmin Liu, Danning Li, Zimeng Han, Linfeng Xi, Wenyi Kou, Jiangnan Xu, Tao-Sheng Li,  and Yaozhong Ding
45678-45686
Abstract  |  PDF  |  HTML  |  Order a Reprint

miR-26a desensitizes non-small cell lung cancer cells to tyrosine kinase inhibitors by targeting PTPN13

miR-26a desensitizes non-small cell lung cancer cells to tyrosine kinase inhibitors by targeting PTPN13

https://doi.org/10.18632/oncotarget.9920

Shudi Xu, Tao Wang, Zhiwei Yang, Ying Li, Weijie Li, Ting Wang, Shan Wang, Lintao Jia, Shengli Zhang,  and Shengqing Li
45687-45701
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Fibrotic microenvironment promotes the metastatic seeding of tumor cells via activating the fibronectin 1/secreted phosphoprotein 1-integrin signaling

Fibrotic microenvironment promotes the metastatic seeding of tumor cells via activating the fibronectin 1/secreted phosphoprotein 1-integrin signaling

https://doi.org/10.18632/oncotarget.10157

Chong Zhang, Mengzhi Wu, Lizhen Zhang, Li-Ru Shang, Jian-Hong Fang,  and Shi-Mei Zhuang
45702-45714
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Calcineurin complex isolated from T-cell acute lymphoblastic leukemia (T-ALL) cells identifies new signaling pathways including mTOR/AKT/S6K whose inhibition synergize with calcineurin inhibition to promote T-ALL cell death

Calcineurin complex isolated from T-cell acute lymphoblastic leukemia (T-ALL) cells identifies new signaling pathways including mTOR/AKT/S6K whose inhibition synergize with calcineurin inhibition to promote T-ALL cell death

https://doi.org/10.18632/oncotarget.9933

Valeria Tosello, Valentina Saccomani, Jiyang Yu, Fulvio Bordin, Alberto Amadori,  and Erich Piovan
45715-45729
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

STAT5 induces miR-21 expression in cutaneous T cell lymphoma

STAT5 induces miR-21 expression in cutaneous T cell lymphoma

https://doi.org/10.18632/oncotarget.10160

Lise M. Lindahl, Simon Fredholm, Claudine Joseph, Boye Schnack Nielsen, Lars Jønson, Andreas Willerslev-Olsen, Maria Gluud, Edda Blümel, David L. Petersen, Nina Sibbesen, Tengpeng Hu, Claudia Nastasi, Thorbjørn Krejsgaard, Ditte Jæhger, Jenny L. Persson, Nigel Mongan, Mariusz A. Wasik, Ivan V. Litvinov, Denis Sasseville, Sergei B. Koralov, Charlotte M. Bonefeld, Carsten Geisler, Anders Woetmann, Elisabeth Ralfkiaer, Lars Iversen,  and Niels Odum
45730-45744
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The relevance of using 3D cell cultures, in addition to 2D monolayer cultures, when evaluating breast cancer drug sensitivity and resistance

The relevance of using 3D cell cultures, in addition to 2D monolayer cultures, when evaluating breast cancer drug sensitivity and resistance

https://doi.org/10.18632/oncotarget.9935

Susan Breslin,  and Lorraine O'Driscoll
45745-45756
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Systematic analyses and comprehensive field synopsis of genetic association studies in hepatocellular carcinoma

Systematic analyses and comprehensive field synopsis of genetic association studies in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9937

Dong Dong, Yang Zou, Pan Zhang,  and Zhihong Wu
45757-45763
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A 4-miRNA signature predicts the therapeutic outcome of glioblastoma

A 4-miRNA signature predicts the therapeutic outcome of glioblastoma

https://doi.org/10.18632/oncotarget.9945

Michel Mittelbronn, Joachim Steinbach, Carsten Sticht, Franz Zehentmayr, Daniel Piehlmaier, Horst Zitzelsberger, Ute Ganswindt, Claus Rödel, Kirsten Lauber, Claus Belka,  and Kristian Unger
45764-45775
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of CHEK1, SLC26A4, c-KIT, TPO and TG as new biomarkers for human follicular thyroid carcinoma

Identification of CHEK1, SLC26A4, c-KIT, TPO and TG as new biomarkers for human follicular thyroid carcinoma

https://doi.org/10.18632/oncotarget.10166

Anne-Marie Makhlouf, Zhanna Chitikova, Marc Pusztaszeri, Margaret Berczy, Celine Delucinge-Vivier, Frederic Triponez, Patrick Meyer, Jacques Philippe,  and Charna Dibner
45776-45788
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impaired lymphatic function accelerates cancer growth

Impaired lymphatic function accelerates cancer growth

https://doi.org/10.18632/oncotarget.9953

Eli Sihn Samdal Steinskog, Solfrid Johanne Sagstad, Marek Wagner, Tine Veronica Karlsen, Ning Yang, Carl Erik Markhus, Synnøve Yndestad, Helge Wiig,  and Hans Petter Eikesdal
45789-45802
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Over-expression of AURKA, SKA3 and DSN1 contributes to colorectal adenoma to carcinoma progression

Over-expression of AURKA, SKA3 and DSN1 contributes to colorectal adenoma to carcinoma progression

https://doi.org/10.18632/oncotarget.9960

Tzu-Po Chuang, Jaw-Yuan Wang, Shu-Wen Jao, Chang-Chieh Wu, Jiann-Hwa Chen, Koung-Hung Hsiao, Chung-Yen Lin, Shu-Hwa Chen, Sheng-Yao Su, Ying-Ju Chen, Yuan-Tsong Chen, Deng-Chyang Wu,  and Ling-Hui Li
45803-45818
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TES inhibits colorectal cancer progression through activation of p38

TES inhibits colorectal cancer progression through activation of p38

https://doi.org/10.18632/oncotarget.9961

Huili Li, Kun Huang, Lu Gao, Lixia Wang, Yanfeng Niu, Hongli Liu, Zheng Wang, Lin Wang, Guobin Wang,  and Jiliang Wang
45819-45836
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nicotinamide N-methyltransferase enhances resistance to 5-fluorouracil in colorectal cancer cells through inhibition of the ASK1-p38 MAPK pathway

Nicotinamide N-methyltransferase enhances resistance to 5-fluorouracil in colorectal cancer cells through inhibition of the ASK1-p38 MAPK pathway

https://doi.org/10.18632/oncotarget.9962

Xinyou Xie, Huixing Liu, Yanzhong Wang, Yanwen Zhou, Haitao Yu, Guiling Li, Zhi Ruan, Fengying Li, Xiuhong Wang,  and Jun Zhang
45837-45848
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumor suppressor berberine binds VASP to inhibit cell migration in basal-like breast cancer

Tumor suppressor berberine binds VASP to inhibit cell migration in basal-like breast cancer

https://doi.org/10.18632/oncotarget.9968

Ke Su, Pengchao Hu, Xiaolan Wang, Changchun Kuang, Qingmin Xiang, Fang Yang, Jin Xiang, Shan Zhu, Lei Wei,  and Jingwei Zhang
45849-45862
Abstract  |  PDF  |  HTML  |  Order a Reprint

Chromatin remodeling gene ARID2 targets cyclin D1 and cyclin E1 to suppress hepatoma cell progression

Chromatin remodeling gene ARID2 targets cyclin D1 and cyclin E1 to suppress hepatoma cell progression

https://doi.org/10.18632/oncotarget.10244

Yujie Duan, Ling Tian, Qingzhu Gao, Li Liang, Wenlu Zhang, Yi Yang, Yaqiu Zheng, E Pan, Shengwei Li,  and Ni Tang
45863-45875
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Downregulation of vimentin expression increased drug resistance in ovarian cancer cells

Downregulation of vimentin expression increased drug resistance in ovarian cancer cells

https://doi.org/10.18632/oncotarget.9970

Yi Huo, Zhiguo Zheng, Yuling Chen, Qingtao Wang, Zhenyu Zhang,  and Haiteng Deng
45876-45888
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Aqueous Oldenlandia diffusa extracts inhibits colorectal cancer cells via activating AMP-activated protein kinase signalings

Aqueous Oldenlandia diffusa extracts inhibits colorectal cancer cells via activating AMP-activated protein kinase signalings

https://doi.org/10.18632/oncotarget.9969

Pei-Hua Lu, Min-Bin Chen, Chao Ji, Wen-Ting Li, Mu-Xin Wei,  and Mian-Hua Wu
45889-45900
Abstract  |  PDF  |  HTML  |  Order a Reprint

NF-Y loss triggers p53 stabilization and apoptosis in HPV18-positive cells by affecting E6 transcription

NF-Y loss triggers p53 stabilization and apoptosis in HPV18-positive cells by affecting E6 transcription

https://doi.org/10.18632/oncotarget.9974

Paolo Benatti, Valentina Basile, Diletta Dolfini, Silvia Belluti, Margherita Tomei,  and Carol Imbriano
45901-45915
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pharmacological inhibitors of c-KIT block mutant c-KIT mediated migration of melanocytes and melanoma cells in vitro and in vivo

Pharmacological inhibitors of c-KIT block mutant c-KIT mediated migration of melanocytes and melanoma cells in vitro and in vivo

https://doi.org/10.18632/oncotarget.10001

Christian Posch, Homayoun Moslehi, Martina Sanlorenzo, Gary Green, Igor Vujic, Renate Panzer-Grümayer, Klemens Rappersberger,  and Susana Ortiz-Urda
45916-45925
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Assessing the clinical utility of genomic expression data across human cancers

Assessing the clinical utility of genomic expression data across human cancers

https://doi.org/10.18632/oncotarget.10002

Xinsen Xu, Lei Huang, Chun Hei Chan, Tao Yu, Runchen Miao,  and Chang Liu
45926-45936
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Construction of a lncRNA-mediated feed-forward loop network reveals global topological features and prognostic motifs in human cancers

Construction of a lncRNA-mediated feed-forward loop network reveals global topological features and prognostic motifs in human cancers

https://doi.org/10.18632/oncotarget.10004

Shangwei Ning, Yue Gao, Peng Wang, Xiang Li, Hui Zhi, Yan Zhang, Yue Liu, Jizhou Zhang, Maoni Guo, Dong Han,  and Xia Li
45937-45947
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FMLNCSIM: fuzzy measure-based lncRNA functional similarity calculation model

FMLNCSIM: fuzzy measure-based lncRNA functional similarity calculation model

https://doi.org/10.18632/oncotarget.10008

Xing Chen, Yu-An Huang, Xue-Song Wang, Zhu-Hong You,  and Keith C.C. Chan
45948-45958
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Characterization of RON protein isoforms in pancreatic cancer: implications for biology and therapeutics

Characterization of RON protein isoforms in pancreatic cancer: implications for biology and therapeutics

https://doi.org/10.18632/oncotarget.10009

Jeffery Chakedis, Randall French, Michele Babicky, Dawn Jaquish, Evangeline Mose, Peter Cheng, Patrick Holman, Haleigh Howard, Jaclyn Miyamoto, Paula Porras, Zakk Walterscheid, Carsten Schultz-Fademrecht, Christina Esdar, Oliver Schadt, Jan Eickhoff,  and Andrew M. Lowy
45959-45975
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR146a-mediated targeting of FANCM during inflammation compromises genome integrity

miR146a-mediated targeting of FANCM during inflammation compromises genome integrity

https://doi.org/10.18632/oncotarget.10275

Devakumar Sundaravinayagam, Hye Rim Kim, TingTing Wu, Hyun Hee Kim, Hyun-Seo Lee, Semo Jun, Jeong-Heon Cha, Younghoon Kee, Ho Jin You,  and Jung-Hee Lee
45976-45994
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression of Cathepsin L is associated with chemoresistance and invasion of epithelial ovarian cancer

Overexpression of Cathepsin L is associated with chemoresistance and invasion of epithelial ovarian cancer

https://doi.org/10.18632/oncotarget.10276

Hongying Sui, Caixia Shi, Zhipeng Yan,  and Mei Wu
45995-46001
Abstract  |  PDF  |  HTML  |  Order a Reprint

PiwiRNA-651 as marker of treatment response and survival in classical Hodgkin lymphoma

PiwiRNA-651 as marker of treatment response and survival in classical Hodgkin lymphoma

https://doi.org/10.18632/oncotarget.10015

Anna Cordeiro, Alfons Navarro, Anna Gaya, Marina Díaz-Beyá, Blanca Gonzalez- Farré, Joan Josep Castellano, Dolors Fuster, Carmen Martínez, Antonio Martínez,  and Mariano Monzó
46002-46013
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Co-existence of IL7R high and SH2B3 low expression distinguishes a novel high-risk acute lymphoblastic leukemia with Ikaros dysfunction

Co-existence of IL7R high and SH2B3 low expression distinguishes a novel high-risk acute lymphoblastic leukemia with Ikaros dysfunction

https://doi.org/10.18632/oncotarget.10014

Zheng Ge, Yan Gu, Lichan Xiao, Qi Han, Jianyong Li, Baoan Chen, James Yu, Yuka Imamura Kawasawa, Kimberly J. Payne, Sinisa Dovat,  and Chunhua Song
46014-46027
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Fucoidan enhances the therapeutic potential of arsenic trioxide and all-trans retinoic acid in acute promyelocytic leukemia, in vitro and in vivo

Fucoidan enhances the therapeutic potential of arsenic trioxide and all-trans retinoic acid in acute promyelocytic leukemia, in vitro and in vivo

https://doi.org/10.18632/oncotarget.10016

Farzaneh Atashrazm, Ray M. Lowenthal, Joanne L. Dickinson, Adele F. Holloway,  and Gregory M. Woods
46028-46041
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High-level expression of P21-Cdc/Rac-activated kinase 7 is closely related to metastatic potential and poor prognosis of colon carcinoma

High-level expression of P21-Cdc/Rac-activated kinase 7 is closely related to metastatic potential and poor prognosis of colon carcinoma

https://doi.org/10.18632/oncotarget.10017

Chao Li, Jian Chen, Yupeng Wang, Guohe Song, Chao Xiao, Dongwang Yan, Lin Zhong, Xing Sun, Xiaoliang Wang, Fudong Yu, Yang Yu, Huamei Tang,  and Zhihai Peng
46042-46055
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression of TELO2 decreases survival in human high-grade gliomas

Overexpression of TELO2 decreases survival in human high-grade gliomas

https://doi.org/10.18632/oncotarget.10021

Shao-Wei Feng, Ying Chen, Wen-Chiuan Tsai, Hsin-Ying Clair Chiou, Sheng-Tang Wu, Li-Chun Huang, Chin Lin, Chih-Chuan Hsieh, Yun-Ju Yang,  and Dueng-Yuan Hueng
46056-46066
Abstract  |  PDF  |  HTML  |  Order a Reprint

CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements

CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements

https://doi.org/10.18632/oncotarget.10022

Klaartje Somers, Daria A. Chudakova, Shiloh M.C. Middlemiss, Victoria W. Wen, Molly Clifton, Alan Kwek, Bing Liu, Chelsea Mayoh, Angelika Bongers, Mawar Karsa, Sukey Pan, Sarah Cruikshank, Marissa Scandlyn, Wendi Hoang, Toshihiko Imamura, Ursula R. Kees, Andrei V. Gudkov, Olga B. Chernova, Michelle Haber, Murray D. Norris,  and Michelle J. Henderson
46067-46087
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SRF promotes gastric cancer metastasis through stromal fibroblasts in an SDF1-CXCR4-dependent manner

SRF promotes gastric cancer metastasis through stromal fibroblasts in an SDF1-CXCR4-dependent manner

https://doi.org/10.18632/oncotarget.10024

Juanli Qiao, Zhaojun Liu, Chen Yang, Liankun Gu,  and Dajun Deng
46088-46099
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Methamphetamine-mediated endoplasmic reticulum (ER) stress induces type-1 programmed cell death in astrocytes via ATF6, IRE1α and PERK pathways

Methamphetamine-mediated endoplasmic reticulum (ER) stress induces type-1 programmed cell death in astrocytes via ATF6, IRE1α and PERK pathways

https://doi.org/10.18632/oncotarget.10025

Ankit Shah,  and Anil Kumar
46100-46119
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression of tumor antigens on primary ovarian cancer cells compared to established ovarian cancer cell lines

Expression of tumor antigens on primary ovarian cancer cells compared to established ovarian cancer cell lines

https://doi.org/10.18632/oncotarget.10028

Kamila Kloudová, Hana Hromádková, Simona Partlová, Tomáš Brtnický, Lukáš Rob, Jiřina Bartůňková, Michal Hensler, Michael J. Halaška, Radek Špíšek,  and Anna Fialová
46120-46126
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Chromatin remodeling gene AT-rich interactive domain-containing protein 1A suppresses gastric cancer cell proliferation by targeting PIK3CA and PDK1

Chromatin remodeling gene AT-rich interactive domain-containing protein 1A suppresses gastric cancer cell proliferation by targeting PIK3CA and PDK1

https://doi.org/10.18632/oncotarget.10060

Qian Zhang, Hai-Bo Yan, Jie Wang, Shu-Jian Cui, Xiao-Qing Wang, Ying-Hua Jiang, Li Feng, Peng-Yuan Yang,  and Feng Liu
46127-46141
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The a3 isoform of subunit a of the vacuolar ATPase localizes to the plasma membrane of invasive breast tumor cells and is overexpressed in human breast cancer

The a3 isoform of subunit a of the vacuolar ATPase localizes to the plasma membrane of invasive breast tumor cells and is overexpressed in human breast cancer

https://doi.org/10.18632/oncotarget.10063

Kristina Cotter, Rachel Liberman, GeHong Sun-Wada, Yoh Wada, Dennis Sgroi, Stephen Naber, Dennis Brown, Sylvie Breton,  and Michael Forgac
46142-46157
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Could gut microbiota serve as prognostic biomarker associated with colorectal cancer patients' survival? A pilot study on relevant mechanism

Could gut microbiota serve as prognostic biomarker associated with colorectal cancer patients' survival? A pilot study on relevant mechanism

https://doi.org/10.18632/oncotarget.10064

Zhiliang Wei, Shougen Cao, Shanglong Liu, Zengwu Yao, Teng Sun, Yi Li, Jiante Li, Dongfeng Zhang,  and Yanbing Zhou
46158-46172
Abstract  |  PDF  |  HTML  |  Order a Reprint

Co-expression of CD40L with CD70 or OX40L increases B-cell viability and antitumor efficacy

Co-expression of CD40L with CD70 or OX40L increases B-cell viability and antitumor efficacy

https://doi.org/10.18632/oncotarget.10068

Chang-Ae Shin, Hyun-Woo Cho, A-Ri Shin, Hyun-Jung Sohn, Hyun-Il Cho,  and Tai-Gyu Kim
46173-46186
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Frizzled2 signaling regulates growth of high-risk neuroblastomas by interfering with β-catenin-dependent and β-catenin-independent signaling pathways

Frizzled2 signaling regulates growth of high-risk neuroblastomas by interfering with β-catenin-dependent and β-catenin-independent signaling pathways

https://doi.org/10.18632/oncotarget.10070

Karin Zins, Romana Schäfer, Patrick Paulus, Silvia Dobler, Nazak Fakhari, Mouldy Sioud, Seyedhossein Aharinejad,  and Dietmar Abraham
46187-46202
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TP53 mutant MDM2-amplified cell lines selected for resistance to MDM2-p53 binding antagonists retain sensitivity to ionizing radiation

TP53 mutant MDM2-amplified cell lines selected for resistance to MDM2-p53 binding antagonists retain sensitivity to ionizing radiation

https://doi.org/10.18632/oncotarget.10073

Catherine J. Drummond, Arman Esfandiari, Junfeng Liu, Xiaohong Lu, Claire Hutton, Jennifer Jackson, Karim Bennaceur, Qing Xu, Aditya Rao Makimanejavali, Fabio Del Bello, Alessandro Piergentili, David R. Newell, Ian R. Hardcastle, Roger J. Griffin,  and John Lunec
46203-46218
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Simvastatin induces heme oxygenase-1 via NF-E2-related factor 2 (Nrf2) activation through ERK and PI3K/Akt pathway in colon cancer

Simvastatin induces heme oxygenase-1 via NF-E2-related factor 2 (Nrf2) activation through ERK and PI3K/Akt pathway in colon cancer

https://doi.org/10.18632/oncotarget.10078

Hyun Joo Jang, Eun Mi Hong, Mikang Kim, Jae Hyun Kim, Juah Jang, Se Woo Park, Hyun Wu Byun, Dong Hee Koh, Min Ho Choi, Sea Hyub Kae,  and Jin Lee
46219-46229
Abstract  |  PDF  |  HTML  |  Order a Reprint

Metformin mediates resensitivity to 5-fluorouracil in hepatocellular carcinoma via the suppression of YAP

Metformin mediates resensitivity to 5-fluorouracil in hepatocellular carcinoma via the suppression of YAP

https://doi.org/10.18632/oncotarget.10079

Yu Tian, Bo Tang, Chengye Wang, Deguang Sun, Rixin Zhang, Nan Luo, Zhao Han, Rui Liang, Zhenming Gao,  and Liming Wang
46230-46241
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevated plasma fibrinogen level shows superior prognostic value than Epstein–Barr virus DNA load for stage IVA/B nasopharyngeal carcinoma patients in the intensity-modulated radiotherapy era

Elevated plasma fibrinogen level shows superior prognostic value than Epstein–Barr virus DNA load for stage IVA/B nasopharyngeal carcinoma patients in the intensity-modulated radiotherapy era

https://doi.org/10.18632/oncotarget.10083

Mei Lan, Chunyan Chen, Ying Huang, Minjie Mao, Fei Han, Junfang Liao, Meiling Deng, Zhijun Duan, Lie Zheng, Shaoxiong Wu, Taixiang Lu,  and Yutao Jian
46242-46252
Abstract  |  PDF  |  HTML  |  Order a Reprint

Elevated expression of FABP3 and FABP4 cooperatively correlates with poor prognosis in non-small cell lung cancer (NSCLC)

Elevated expression of FABP3 and FABP4 cooperatively correlates with poor prognosis in non-small cell lung cancer (NSCLC)

https://doi.org/10.18632/oncotarget.10086

Zhiyuan Tang, Qin Shen, Hao Xie, Xiaoyu Zhou, Jun Li, Jian Feng, Hua Liu, Wei Wang, Shu Zhang,  and Songshi Ni
46253-46262
Abstract  |  PDF  |  HTML  |  Order a Reprint

Alveolar rhabdomyosarcoma: morphoproteomics and personalized tumor graft testing further define the biology of PAX3-FKHR(FOXO1) subtype and provide targeted therapeutic options

Alveolar rhabdomyosarcoma: morphoproteomics and personalized tumor graft testing further define the biology of PAX3-FKHR(FOXO1) subtype and provide targeted therapeutic options

https://doi.org/10.18632/oncotarget.10089

Robert E. Brown, Jamie Buryanek, Amanda M. Katz, Keren Paz,  and Johannes E. Wolff
46263-46272
Abstract  |  PDF  |  HTML  |  Order a Reprint

National incidence of autoimmune liver diseases and its relationship with the human development index

National incidence of autoimmune liver diseases and its relationship with the human development index

https://doi.org/10.18632/oncotarget.10090

Hong-Ying Pan, Yi-Ning Dai, Ji-Na Zheng, Ke-Qing Shi, Sven Van Poucke, Hai Zou,  and Ming-Hua Zheng
46273-46282
Abstract  |  PDF  |  HTML  |  Order a Reprint

RING1B contributes to Ewing sarcoma development by repressing the NaV1.6 sodium channel and the NF-κB pathway, independently of the fusion oncoprotein

RING1B contributes to Ewing sarcoma development by repressing the NaV1.6 sodium channel and the NF-κB pathway, independently of the fusion oncoprotein

https://doi.org/10.18632/oncotarget.10092

Inmaculada Hernandez-Muñoz, Elisabeth Figuerola, Sara Sanchez-Molina, Eva Rodriguez, Ana Isabel Fernández-Mariño, Carlos Pardo-Pastor, María Isabel Bahamonde, José M. Fernández-Fernández, Daniel J. García-Domínguez, Lourdes Hontecillas-Prieto, Cinzia Lavarino, Angel M. Carcaboso, Carmen de Torres, Oscar M. Tirado, Enrique de Alava,  and Jaume Mora
46283-46300
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Deregulation of SOCS5 suppresses dendritic cell function in chronic lymphocytic leukemia

Deregulation of SOCS5 suppresses dendritic cell function in chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.10093

Patricia A. Toniolo, Suhu Liu, Jennifer E. Yeh, Darwin Q. Ye, José Alexandre M. Barbuto,  and David A. Frank
46301-46314
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Disintegrin targeting of an αvβ3 integrin-over-expressing high-metastatic human osteosarcoma with echistatin inhibits cell proliferation, migration, invasion and adhesion in vitro

Disintegrin targeting of an αvβ3 integrin-over-expressing high-metastatic human osteosarcoma with echistatin inhibits cell proliferation, migration, invasion and adhesion in vitro

https://doi.org/10.18632/oncotarget.10111

Yasunori Tome, Hiroaki Kimura, Tasuku Kiyuna, Naotoshi Sugimoto, Hiroyuki Tsuchiya, Fuminori Kanaya, Michael Bouvet,  and Robert M. Hoffman
46315-46320
Abstract  |  PDF  |  HTML  |  Order a Reprint

Caveolin-1 regulates hormone resistance through lipid synthesis, creating novel therapeutic opportunities for castration-resistant prostate cancer

Caveolin-1 regulates hormone resistance through lipid synthesis, creating novel therapeutic opportunities for castration-resistant prostate cancer

https://doi.org/10.18632/oncotarget.10113

Theodoros Karantanos, Styliani Karanika, Jianxiang Wang, Guang Yang, Masato Dobashi, Sanghee Park, Chengzhen Ren, Likun Li, Spyridon P. Basourakos, Anh Hoang, Eleni Efstathiou, Xuemei Wang, Patricia Troncoso, Mark Titus, Bradley Broom, Jeri Kim, Paul G. Corn, Christopher J. Logothetis,  and Timothy C. Thompson
46321-46334
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hypoxia-mediated upregulation of MCT1 expression supports the glycolytic phenotype of glioblastomas

Hypoxia-mediated upregulation of MCT1 expression supports the glycolytic phenotype of glioblastomas

https://doi.org/10.18632/oncotarget.10114

Vera Miranda-Gonçalves, Sara Granja, Olga Martinho, Mrinalini Honavar, Marta Pojo, Bruno M. Costa, Manuel M. Pires, Célia Pinheiro, Michelle Cordeiro, Gil Bebiano, Paulo Costa, Rui M. Reis,  and Fátima Baltazar
46335-46353
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epac1 links prostaglandin E2 to β-catenin-dependent transcription during epithelial-to-mesenchymal transition

Epac1 links prostaglandin E2 to β-catenin-dependent transcription during epithelial-to-mesenchymal transition

https://doi.org/10.18632/oncotarget.10128

Sepp R. Jansen, Wilfred J. Poppinga, Wim de Jager, Frank Lezoualc'h, Xiaodong Cheng, Thomas Wieland, Stephen J. Yarwood, Reinoud Gosens,  and Martina Schmidt
46354-46370
Abstract  |  PDF  |  HTML  |  Order a Reprint

Inhibition of glucose metabolism prevents glycosylation of the glutamine transporter ASCT2 and promotes compensatory LAT1 upregulation in leukemia cells

Inhibition of glucose metabolism prevents glycosylation of the glutamine transporter ASCT2 and promotes compensatory LAT1 upregulation in leukemia cells

https://doi.org/10.18632/oncotarget.10131

Florence Polet, Ruben Martherus, Cyril Corbet, Adan Pinto,  and Olivier Feron
46371-46383
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Critical function of the necroptosis adaptor RIPK3 in protecting from intestinal tumorigenesis

Critical function of the necroptosis adaptor RIPK3 in protecting from intestinal tumorigenesis

https://doi.org/10.18632/oncotarget.10135

Dominique Bozec, Alina C. Iuga, Giulia Roda, Stephanie Dahan,  and Garabet Yeretssian
46384-46400
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RRD-251 enhances all-trans retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells

RRD-251 enhances all-trans retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells

https://doi.org/10.18632/oncotarget.10136

Aaron S. Wallace, Harrison T. Supnick, Rodica P. Bunaciu,  and Andrew Yen
46401-46418
Abstract  |  PDF  |  HTML  |  Order a Reprint

Myosin 1e promotes breast cancer malignancy by enhancing tumor cell proliferation and stimulating tumor cell de-differentiation

Myosin 1e promotes breast cancer malignancy by enhancing tumor cell proliferation and stimulating tumor cell de-differentiation

https://doi.org/10.18632/oncotarget.10139

Jessica L. Ouderkirk-Pecone, Gregory J. Goreczny, Sharon E. Chase, Arthur H. Tatum, Christopher E. Turner,  and Mira Krendel
46419-46432
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A mechanism for 1,4-Benzoquinone-induced genotoxicity

A mechanism for 1,4-Benzoquinone-induced genotoxicity

https://doi.org/10.18632/oncotarget.10184

Mi Young Son, Chu-Xia Deng, Jan H. Hoeijmarkers, Vivienne I. Rebel,  and Paul Hasty
46433-46447
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Androgen receptor mitigates postoperative disease progression of hepatocellular carcinoma by suppressing CD90+ populations and cell migration and by promoting anoikis in circulating tumor cells

Androgen receptor mitigates postoperative disease progression of hepatocellular carcinoma by suppressing CD90+ populations and cell migration and by promoting anoikis in circulating tumor cells

https://doi.org/10.18632/oncotarget.10186

Hsueh-Chou Lai, Chun-Chieh Yeh, Long-Bin Jeng, Shang-Fen Huang, Pei-Ying Liao, Fu-Ju Lei, Wei-Chun Cheng, Cheng-Lung Hsu, Xiujun Cai, Chawnshang Chang,  and Wen-Lung Ma
46448-46465
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Maintenance therapy with histamine plus IL-2 induces a striking expansion of two CD56bright NK cell subpopulations in patients with acute myeloid leukemia and supports their activation

Maintenance therapy with histamine plus IL-2 induces a striking expansion of two CD56bright NK cell subpopulations in patients with acute myeloid leukemia and supports their activation

https://doi.org/10.18632/oncotarget.10191

Angélica Cuapio, Mirte Post, Sabine Cerny-Reiterer, Karoline V. Gleixner, Gabriele Stefanzl, Jose Basilio, Susanne Herndlhofer, Wolfgang R. Sperr, Nicolaas H.C. Brons, Emilio Casanova, Jacques Zimmer, Peter Valent,  and Erhard Hofer
46466-46481
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value of androgen receptor in triple negative breast cancer: A meta-analysis

Prognostic value of androgen receptor in triple negative breast cancer: A meta-analysis

https://doi.org/10.18632/oncotarget.10208

Changjun Wang, Bo Pan, Hanjiang Zhu, Yidong Zhou, Feng Mao, Yan Lin, Qianqian Xu,  and Qiang Sun
46482-46491
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Desmoglein 2 promotes vasculogenic mimicry in melanoma and is associated with poor clinical outcome

Desmoglein 2 promotes vasculogenic mimicry in melanoma and is associated with poor clinical outcome

https://doi.org/10.18632/oncotarget.10216

Lih Yin Tan, Chris Mintoff, Zahied M. Johan, Brenton W. Ebert, Clare Fedele, You Fang Zhang, Pacman Szeto, Karen E. Sheppard, Grant A. McArthur, Erwin Foster-Smith, Andrew Ruszkiewicz, Michael P. Brown, Claudine S. Bonder, Mark Shackleton,  and Lisa M. Ebert
46492-46508
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer

Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer

https://doi.org/10.18632/oncotarget.10224

Rebecca Swan, Abdo Alnabulsi, Beatriz Cash, Ayham Alnabulsi,  and Graeme I. Murray
46509-46527
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Evaluating prognosis by CK7 differentiating renal cell carcinomas from oncocytomas can be used as a promising tool for optimizing diagnosis strategies

Evaluating prognosis by CK7 differentiating renal cell carcinomas from oncocytomas can be used as a promising tool for optimizing diagnosis strategies

https://doi.org/10.18632/oncotarget.10225

Fuling Ma, Liang Dai, Zhun Wang, Liqun Zhou, Yuanjie Niu,  and Ning Jiang
46528-46535
Abstract  |  PDF  |  HTML  |  Order a Reprint

Possible contribution of IMRT in postoperative radiochemotherapy for rectal cancer: analysis on 1798 patients by prediction model

Possible contribution of IMRT in postoperative radiochemotherapy for rectal cancer: analysis on 1798 patients by prediction model

https://doi.org/10.18632/oncotarget.10228

Wen-Yang Liu, Nicola Dinapoli, Xin Wang, Elisa Meldolesi, Maria Antonietta Gambacorta, Giuditta Chiloiro, Hua Ren, Hui Fang, Ning-Ning Lu, Yu Tang, Lei Deng, Jian-Yang Wang, Hao Jing, Qin Xiao, Yan-Ru Feng, Ye-Xiong Li, Shu-Lian Wang, Yong-Wen Song, Yue-Ping Liu, Wei-Hu Wang, Vincenzo Valentini,  and Jing Jin
46536-46544
Abstract  |  PDF  |  HTML  |  Order a Reprint

CRISPR-dCas9 mediated TET1 targeting for selective DNA demethylation at BRCA1 promoter

CRISPR-dCas9 mediated TET1 targeting for selective DNA demethylation at BRCA1 promoter

https://doi.org/10.18632/oncotarget.10234

Samrat Roy Choudhury, Yi Cui, Katarzyna Lubecka, Barbara Stefanska,  and Joseph Irudayaraj
46545-46556
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metabolomics profiles delineate uridine deficiency contributes to mitochondria-mediated apoptosis induced by celastrol in human acute promyelocytic leukemia cells

Metabolomics profiles delineate uridine deficiency contributes to mitochondria-mediated apoptosis induced by celastrol in human acute promyelocytic leukemia cells

https://doi.org/10.18632/oncotarget.10286

Xiaoling Zhang, Jing Yang, Minjian Chen, Lei Li, Fei Huan, Aiping Li, Yanqing Liu, Yankai Xia, Jin-ao Duan,  and Shiping Ma
46557-46572
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Measuring PC activity in endocervical swab may provide a simple and non-invasive method to detect endometrial cancer in post-menopausal women

Measuring PC activity in endocervical swab may provide a simple and non-invasive method to detect endometrial cancer in post-menopausal women

https://doi.org/10.18632/oncotarget.10287

Sophea Heng, Andrew N. Stephens, Tom W. Jobling,  and Guiying Nie
46573-46578
Abstract  |  PDF  |  HTML  |  Order a Reprint

Basal autophagy is pivotal for Hodgkin and Reed-Sternberg cells’ survival and growth revealing a new strategy for Hodgkin lymphoma treatment

Basal autophagy is pivotal for Hodgkin and Reed-Sternberg cells’ survival and growth revealing a new strategy for Hodgkin lymphoma treatment

https://doi.org/10.18632/oncotarget.10300

Katrin Birkenmeier, Katharina Moll, Sebastian Newrzela, Sylvia Hartmann, Stefan Dröse,  and Martin-Leo Hansmann
46579-46588
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ART3 regulates triple-negative breast cancer cell function via activation of Akt and ERK pathways

ART3 regulates triple-negative breast cancer cell function via activation of Akt and ERK pathways

https://doi.org/10.18632/oncotarget.10306

Ling Tan, Xiaodan Song, Xin Sun, Ning Wang, Ying Qu,  and Zhijun Sun
46589-46602
Abstract  |  PDF  |  HTML  |  Order a Reprint

Delta-9-tetrahydrocannabinol protects against MPP+ toxicity in SH-SY5Y cells by restoring proteins involved in mitochondrial biogenesis

Delta-9-tetrahydrocannabinol protects against MPP+ toxicity in SH-SY5Y cells by restoring proteins involved in mitochondrial biogenesis

https://doi.org/10.18632/oncotarget.10314

Marie-Louise Zeissler, Jordan Eastwood, Kieran McCorry, Oliver C. Hanemann, John P. Zajicek,  and Camille B. Carroll
46603-46614
Abstract  |  PDF  |  HTML  |  Order a Reprint

ERK1/2/MAPK pathway-dependent regulation of the telomeric factor TRF2

ERK1/2/MAPK pathway-dependent regulation of the telomeric factor TRF2

https://doi.org/10.18632/oncotarget.10316

Vincent Picco, Isabelle Coste, Marie-Josèphe Giraud-Panis, Toufic Renno, Eric Gilson,  and Gilles Pagès
46615-46627
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Characteristics of young lung cancer: Analysis of Taiwan's nationwide lung cancer registry focusing on epidermal growth factor receptor mutation and smoking status

Characteristics of young lung cancer: Analysis of Taiwan's nationwide lung cancer registry focusing on epidermal growth factor receptor mutation and smoking status

https://doi.org/10.18632/oncotarget.9338

Chia-Hung Hsu, Chien-Hua Tseng, Chun-Ju Chiang, Kuo-Hsuan Hsu, Jeng-Sen Tseng, Kun-Chieh Chen, Chih-Liang Wang, Chih-Yi Chen, Sang-Hue Yen, Chao-Hua Chiu, Ming-Shyan Huang, Chong-Jen Yu, Ying-Huang Tsai, Jin-Shing Chen, Chun-Ming Tsai, Teh-Ying Chou, Kuei-Chih Lin, Ming-Hsun Tsai, Wen-Chung Lee, Hsiu-Ying Ku, Tsang-Wu Liu, Tsung-Ying Yang,  and Gee-Chen Chang
46628-46635
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Effect of nodal status on clinical outcomes of triple-negative breast cancer: a population-based study using the SEER 18 database

Effect of nodal status on clinical outcomes of triple-negative breast cancer: a population-based study using the SEER 18 database

https://doi.org/10.18632/oncotarget.9432

Xiao-Xiao Wang, Yi-Zhou Jiang, Jun-Jing Li, Chuan-Gui Song,  and Zhi-Ming Shao
46636-46645
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Survival benefits from postoperative radiation therapy on lymph node positive patients with pancreatic adenocarcinoma

Survival benefits from postoperative radiation therapy on lymph node positive patients with pancreatic adenocarcinoma

https://doi.org/10.18632/oncotarget.9620

Zuguang Xia, Xiaoyan Jia, Kai Chen, Dapeng Li, Jing Xie, Hong Xu,  and Yixiang Mao
46646-46652
Abstract  |  PDF  |  HTML  |  Order a Reprint

A prognostic model combining CD4/CD8 ratio and N stage predicts the risk of distant metastasis for patients with nasopharyngeal carcinoma treated by intensity modulated radiotherapy

A prognostic model combining CD4/CD8 ratio and N stage predicts the risk of distant metastasis for patients with nasopharyngeal carcinoma treated by intensity modulated radiotherapy

https://doi.org/10.18632/oncotarget.9695

Chang-Juan Tao, Yuan-Yuan Chen, Feng Jiang, Xing-Lai Feng, Qi-Feng Jin, Ting Jin, Yong-Feng Piao,  and Xiao-Zhong Chen
46653-46661
Abstract  |  PDF  |  HTML  |  Order a Reprint

Setup uncertainties for inter-fractional head and neck cancer in radiotherapy

Setup uncertainties for inter-fractional head and neck cancer in radiotherapy

https://doi.org/10.18632/oncotarget.9748

Eun–Tae Park,  and Sung Kwang Park
46662-46667
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

Tumor refractoriness to anti-VEGF therapy

Tumor refractoriness to anti-VEGF therapy

https://doi.org/10.18632/oncotarget.8694

Domenico Ribatti
46668-46677
Abstract  |  PDF  |  HTML  |  Order a Reprint

Relationship between hypoxia and response to antiangiogenic therapy in metastatic colorectal cancer

Relationship between hypoxia and response to antiangiogenic therapy in metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.8712

Paola Ulivi, Giorgia Marisi,  and Alessandro Passardi
46678-46691
Abstract  |  PDF  |  HTML  |  Order a Reprint

Changing perspective on oncometabolites: from metabolic signature of cancer to tumorigenic and immunosuppressive agents

Changing perspective on oncometabolites: from metabolic signature of cancer to tumorigenic and immunosuppressive agents

https://doi.org/10.18632/oncotarget.8727

Mauro Corrado, Luca Scorrano,  and Silvia Campello
46692-46706
Abstract  |  PDF  |  HTML  |  Order a Reprint

Atlas on substrate recognition subunits of CRL2 E3 ligases

Atlas on substrate recognition subunits of CRL2 E3 ligases

https://doi.org/10.18632/oncotarget.8732

Siwei Wang, Wenjia Xia, Mantang Qiu, Xin Wang, Feng Jiang, Rong Yin,  and Lin Xu
46707-46716
Abstract  |  PDF  |  HTML  |  Order a Reprint

Kirsten Ras* oncogene: Significance of its discovery in human cancer research

Kirsten Ras* oncogene: Significance of its discovery in human cancer research

https://doi.org/10.18632/oncotarget.8773

Nobuo Tsuchida, Avaniyapuram Kannan Murugan,  and Michele Grieco
46717-46733
Abstract  |  PDF  |  HTML  |  Order a Reprint

The challenge of developmental therapeutics for adrenocortical carcinoma

The challenge of developmental therapeutics for adrenocortical carcinoma

https://doi.org/10.18632/oncotarget.8774

Ricardo Costa, Benedito A. Carneiro, Fabio Tavora, Sachin G. Pai, Jason B. Kaplan, Young Kwang Chae, Sunandana Chandra, Peter A. Kopp,  and Francis J. Giles
46734-46749
Abstract  |  PDF  |  HTML  |  Order a Reprint

The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets

The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets

https://doi.org/10.18632/oncotarget.8775

Dawn Q. Chong,  and Andrew X. Zhu
46750-46767
Abstract  |  PDF  |  HTML  |  Order a Reprint

Melatonin as a potential anticarcinogen for non-small-cell lung cancer

Melatonin as a potential anticarcinogen for non-small-cell lung cancer

https://doi.org/10.18632/oncotarget.8776

Zhiqiang Ma, Yang Yang, Chongxi Fan, Jing Han, Dongjin Wang, Shouyin Di, Wei Hu, Dong Liu, Xiaofei Li, Russel J. Reiter,  and Xiaolong Yan
46768-46784
Abstract  |  PDF  |  HTML  |  Order a Reprint

Myosins as fundamental components during tumorigenesis: diverse and indispensable

Myosins as fundamental components during tumorigenesis: diverse and indispensable

https://doi.org/10.18632/oncotarget.8800

Yan-Ruide Li,  and Wan-Xi Yang
46785-46812
Abstract  |  PDF  |  HTML  |  Order a Reprint

Future paradigms for precision oncology

Future paradigms for precision oncology

https://doi.org/10.18632/oncotarget.9488

Giannoula Lakka Klement, Knarik Arkun, Dalibor Valik, Tina Roffidal, Ali Hashemi, Christos Klement, Paolo Carmassi, Edward Rietman, Ondrej Slaby, Pavel Mazanek, Peter Mudry, Gabor Kovacs, Csongor Kiss, Koen Norga, Dobrin Konstantinov, Nicolas André, Irene Slavc, Henk van Den Berg, Alexandra Kolenova, Leos Kren, Jiri Tuma, Jarmila Skotakova,  and Jaroslav Sterba
46813-46831
Abstract  |  PDF  |  HTML  |  Order a Reprint

Corrections

Correction: GDF11/BMP11 activates both smad1/5/8 and smad2/3 signals but shows no significant effect on proliferation and migration of human umbilical vein endothelial cells

Correction: GDF11/BMP11 activates both smad1/5/8 and smad2/3 signals but shows no significant effect on proliferation and migration of human umbilical vein endothelial cells

https://doi.org/10.18632/oncotarget.10664

Yong-Hui Zhang, Feng Cheng, Xue-Ting Du, Jin-Lai Gao, Xiao-Lin Xiao, Na Li, Shan-Liang Li,  and De-Li Dong
46832-46832
Correction  |  PDF


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