Oncotarget

Vol 7, No 27

July 5, 2016

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Upregulation of phospho-AKT signaling in breast cancer cells. See Goswami et al

Table of Contents

Priority Research Papers

Constitutively active transforming growth factor β receptor 1 in the mouse ovary promotes tumorigenesis

Constitutively active transforming growth factor β receptor 1 in the mouse ovary promotes tumorigenesis

https://doi.org/10.18632/oncotarget.10149

Yang Gao, David F. Vincent, Anna Jane Davis, Owen J. Sansom, Laurent Bartholin,  and Qinglei Li
40904-40918
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Research Papers: Pathology

A plasma proteolysis pathway comprising blood coagulation proteases

A plasma proteolysis pathway comprising blood coagulation proteases

https://doi.org/10.18632/oncotarget.7261

Lu Yang, Yun Li, Arup Bhattacharya,  and Yuesheng Zhang
40919-40938
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The PI3K-AKT-mTOR pathway activates recovery from general anesthesia

The PI3K-AKT-mTOR pathway activates recovery from general anesthesia

https://doi.org/10.18632/oncotarget.10172

Yun-Hui Zhang, Jin Zhang, Jian-Nan Song, Xue Xu, Jin-Song Cai, Yang Zhou,  and Jin-Gui Gao
40939-40952
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Research Papers: Immunology

PILRα binds an unknown receptor expressed primarily on CD56bright and decidual-NK cells and activates NK cell functions

PILRα binds an unknown receptor expressed primarily on CD56bright and decidual-NK cells and activates NK cell functions

https://doi.org/10.18632/oncotarget.8397

Yael Ophir, Alexandra Duev-Cohen, Rachel Yamin, Pini Tsukerman, Yoav Bauman, Moriya Gamliel,  and Ofer Mandelboim
40953-40964
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Biochemical and structural characterization of a DNA N6-adenine methyltransferase from Helicobacter pylori

Biochemical and structural characterization of a DNA N6-adenine methyltransferase from Helicobacter pylori

https://doi.org/10.18632/oncotarget.9692

Bo Ma, Ji Ma, Dong Liu, Ling Guo, Huiling Chen, Jingjin Ding, Wei Liu,  and Hongquan Zhang
40965-40977
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4,4’-diaponeurosporene, a C30 carotenoid, effectively activates dendritic cells via CD36 and NF-κB signaling in a ROS independent manner

4,4’-diaponeurosporene, a C30 carotenoid, effectively activates dendritic cells via CD36 and NF-κB signaling in a ROS independent manner

https://doi.org/10.18632/oncotarget.9800

Haofei Liu, Wenwen Xu, Xiaojing Chang, Tao Qin, Yinyan Yin,  and Qian Yang
40978-40991
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Prognostic value, localization and correlation of PD-1/PD-L1, CD8 and FOXP3 with the desmoplastic stroma in pancreatic ductal adenocarcinoma

Prognostic value, localization and correlation of PD-1/PD-L1, CD8 and FOXP3 with the desmoplastic stroma in pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.10038

Angela Diana, Lai Mun Wang, Zenobia D’Costa, Paul Allen, Abul Azad, Michael A. Silva, Zahir Soonawalla, Stanley Liu, W. Gillies McKenna, Ruth J. Muschel,  and Emmanouil Fokas
40992-41004
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Research Papers

Emx2 as a novel tool to suppress glioblastoma

Emx2 as a novel tool to suppress glioblastoma

https://doi.org/10.18632/oncotarget.9322

Carmen Falcone, Antonio Daga, Giampiero Leanza,  and Antonello Mallamaci
41005-41016
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NRAS and EPHB6 mutation rates differ in metastatic melanomas of patients in the North Island versus South Island of New Zealand

NRAS and EPHB6 mutation rates differ in metastatic melanomas of patients in the North Island versus South Island of New Zealand

https://doi.org/10.18632/oncotarget.9351

Angela M. Jones, Peter Ferguson, Jacqui Gardner, Serena Rooker, Tim Sutton, Antonio Ahn, Aniruddha Chatterjee, Vivienne M. Bickley, Makhdoom Sarwar, Patrick Emanuel, Diane Kenwright, Peter R. Shepherd,  and Michael R. Eccles
41017-41030
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Protein kinase D-dependent CXCR4 down-regulation upon BCR triggering is linked to lymphadenopathy in chronic lymphocytic leukaemia

Protein kinase D-dependent CXCR4 down-regulation upon BCR triggering is linked to lymphadenopathy in chronic lymphocytic leukaemia

https://doi.org/10.18632/oncotarget.9031

Stéphane Saint-Georges, Maude Quettier, Marouane Bouyaba, Stéphanie Le Coquil, Vanessa Laurienté, Lionel Guittat, Vincent Lévy, Florence Ajchenbaum-Cymbalista, Nadine Varin-Blank, Christine Le Roy,  and Dominique Ledoux
41031-41046
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Genetic variants of lncRNA HOTAIR and risk of epithelial ovarian cancer among Chinese women

Genetic variants of lncRNA HOTAIR and risk of epithelial ovarian cancer among Chinese women

https://doi.org/10.18632/oncotarget.8535

Haijing Wu, Xiaofei Shang, Yu Shi, Zhirong Yang, Jun Zhao, Min Yang, Yan Li,  and Shiqiang Xu
41047-41052
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Sialic acid removal from dendritic cells improves antigen cross-presentation and boosts anti-tumor immune responses

Sialic acid removal from dendritic cells improves antigen cross-presentation and boosts anti-tumor immune responses

https://doi.org/10.18632/oncotarget.9419

Mariana Silva, Zélia Silva, Graça Marques, Tiago Ferro, Márcia Gonçalves, Mauro Monteiro, Sandra J. van Vliet, Elodie Mohr, Andreia C. Lino, Alexandra R. Fernandes, Flávia A. Lima, Yvette van Kooyk, Teresa Matos, Carlos E. Tadokoro,  and Paula A. Videira
41053-41066
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The novel VEGF receptor 2 inhibitor YLL545 inhibits angiogenesis and growth in breast cancer

The novel VEGF receptor 2 inhibitor YLL545 inhibits angiogenesis and growth in breast cancer

https://doi.org/10.18632/oncotarget.9392

Jianbo Zhang, Chen Liu, Wen Shi, Lingling Yang, Quansheng Zhang, Jianlin Cui, Yangwu Fang, Yuhao Li, Guosheng Ren, Shuang Yang,  and Rong Xiang
41067-41080
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Interferon regulatory factor 4 attenuates Notch signaling to suppress the development of chronic lymphocytic leukemia

Interferon regulatory factor 4 attenuates Notch signaling to suppress the development of chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.9596

Vipul Shukla, Ashima Shukla, Shantaram S. Joshi,  and Runqing Lu
41081-41094
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Proteinase-activated receptor 2 promotes TGF-β-dependent cell motility in pancreatic cancer cells by sustaining expression of the TGF-β type I receptor ALK5

Proteinase-activated receptor 2 promotes TGF-β-dependent cell motility in pancreatic cancer cells by sustaining expression of the TGF-β type I receptor ALK5

https://doi.org/10.18632/oncotarget.9600

Franziska Zeeh, David Witte, Thomas Gädeken, Bernhard H. Rauch, Evelin Grage-Griebenow, Nadja Leinung, Sofie Joline Fromm, Stephanie Stölting, Koichiro Mihara, Roland Kaufmann, Utz Settmacher, Hendrik Lehnert, Morley D. Hollenberg,  and Hendrik Ungefroren
41095-41109
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SUMOylation of TBL1 and TBLR1 promotes androgen-independent prostate cancer cell growth

SUMOylation of TBL1 and TBLR1 promotes androgen-independent prostate cancer cell growth

https://doi.org/10.18632/oncotarget.9002

Soo-Yeon Park, Younghwa Na, Mee-Hee Lee, Jae-Sung Seo, Yoo-Hyun Lee, Kyung-Chul Choi, Hyo-Kyoung Choi,  and Ho-Geun Yoon
41110-41122
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Characterization of Lgr5+ progenitor cell transcriptomes in the apical and basal turns of the mouse cochlea

Characterization of Lgr5+ progenitor cell transcriptomes in the apical and basal turns of the mouse cochlea

https://doi.org/10.18632/oncotarget.8636

Muhammad Waqas, Luo Guo, Shasha Zhang, Yan Chen, Xiaoli Zhang, Lei Wang, Mingliang Tang, Haibo Shi, Phillip I. Bird, Huawei Li,  and Renjie Chai
41123-41141
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Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Reversion or promotion of malignancy by inducing melanogenesis or metastasis

Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Reversion or promotion of malignancy by inducing melanogenesis or metastasis

https://doi.org/10.18632/oncotarget.9220

Candelaria Bracalente, Noelia Salguero, Cintia Notcovich, Carolina B. Müller, Leonardo L. da Motta, Fabio Klamt, Irene L. Ibañez,  and Hebe Durán
41142-41153
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Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Upregulation of antioxidant genes correlates with regression of melanoma malignancy and with malignant progression when downregulated

Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Upregulation of antioxidant genes correlates with regression of melanoma malignancy and with malignant progression when downregulated

https://doi.org/10.18632/oncotarget.9273

Candelaria Bracalente, Irene L. Ibañez, Ariel Berenstein, Cintia Notcovich, María B. Cerda, Fabio Klamt, Ariel Chernomoretz,  and Hebe Durán
41154-41171
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Targeting and killing glioblastoma with monoclonal antibody to O-acetyl GD2 ganglioside

Targeting and killing glioblastoma with monoclonal antibody to O-acetyl GD2 ganglioside

https://doi.org/10.18632/oncotarget.9226

Julien Fleurence, Denis Cochonneau, Sophie Fougeray, Lisa Oliver, Fanny Geraldo, Mickaël Terme, Mylène Dorvillius, Delphine Loussouarn, François Vallette, François Paris,  and Stéphane Birklé
41172-41185
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Identifying and targeting determinants of melanoma cellular invasion

Identifying and targeting determinants of melanoma cellular invasion

https://doi.org/10.18632/oncotarget.9227

Aparna Jayachandran, Prashanth Prithviraj, Pu-Han Lo, Marzena Walkiewicz, Matthew Anaka, Briannyn L. Woods, BeeShin Tan, Andreas Behren, Jonathan Cebon,  and Sonja J. McKeown
41186-41202
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Autophagy gene expression profiling identifies a defective microtubule-associated protein light chain 3A mutant in cancer

Autophagy gene expression profiling identifies a defective microtubule-associated protein light chain 3A mutant in cancer

https://doi.org/10.18632/oncotarget.9754

Joana R. Costa, Krisna Prak, Sarah Aldous, Christina Anja Gewinner,  and Robin Ketteler
41203-41216
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The marrow niche controls the cancer stem cell phenotype of disseminated prostate cancer

The marrow niche controls the cancer stem cell phenotype of disseminated prostate cancer

https://doi.org/10.18632/oncotarget.9251

Yusuke Shiozawa, Janice E. Berry, Matthew R. Eber, Younghun Jung, Kenji Yumoto, Frank C. Cackowski, Hyeun Joong Yoon, Princy Parsana, Rohit Mehra, Jingcheng Wang, Samantha McGee, Eunsohl Lee, Sunitha Nagrath, Kenneth J. Pienta,  and Russell S. Taichman
41217-41232
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The impact of 177Lu-octreotide therapy on 99mTc-MAG3 clearance is not predictive for late nephropathy

The impact of 177Lu-octreotide therapy on 99mTc-MAG3 clearance is not predictive for late nephropathy

https://doi.org/10.18632/oncotarget.9775

Rudolf A. Werner, Seval Beykan, Takahiro Higuchi, Katharina Lückerath, Alexander Weich, Michael Scheurlen, Christina Bluemel, Ken Herrmann, Andreas K. Buck, Michael Lassmann, Constantin Lapa,  and Heribert Hänscheid
41233-41241
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A comparison of R-EPOCH and R-CHOP as a first-line regimen in de novo DLBCL patients with high Ki-67 expression in a single institution

A comparison of R-EPOCH and R-CHOP as a first-line regimen in de novo DLBCL patients with high Ki-67 expression in a single institution

https://doi.org/10.18632/oncotarget.9271

Jia-Jia Huang, Yi Xia, Yu Wang, Pan-Pan Liu, Xi-Wen Bi, Peng Sun, Tong-Yu Lin, Wen-Qi Jiang,  and Zhi-Ming Li
41242-41250
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NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma

NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma

https://doi.org/10.18632/oncotarget.9275

Sanaz Yahyanejad, Henry King, Venus Sosa Iglesias, Patrick V. Granton, Lydie M.O. Barbeau, Stefan J. van Hoof, Arjan J. Groot, Roger Habets, Jos Prickaerts, Anthony J. Chalmers, Daniëlle B.P. Eekers, Jan Theys, Susan C. Short, Frank Verhaegen,  and Marc Vooijs
41251-41264
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Absorbable polymeric surgical clips for appendicular stump closure: A randomized control trial of laparoscopic appendectomy with lapro-clips

Absorbable polymeric surgical clips for appendicular stump closure: A randomized control trial of laparoscopic appendectomy with lapro-clips

https://doi.org/10.18632/oncotarget.9283

Bo Lv, Xin Zhang, Jun Li, Shusheng Leng, Shuqiang Li, Yunlong Zeng, Bing Wang, Jiatian Yuan, Jun Fan, Shasha Xing,  and Ci Li
41265-41273
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Sorafenib-resistant hepatocellular carcinoma stratified by phosphorylated ERK activates PD-1 immune checkpoint

Sorafenib-resistant hepatocellular carcinoma stratified by phosphorylated ERK activates PD-1 immune checkpoint

https://doi.org/10.18632/oncotarget.8978

Jiang Chen, Tong Ji, Jie Zhao, Gaofeng Li, Jian Zhang, Renan Jin, Jinghua Liu, Xiaolong Liu, Xiao Liang, Diyu Huang, Anyong Xie, Hui Lin, Yong Cang,  and Xiujun Cai
41274-41284
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Androgen receptor expression predicts different clinical outcomes for breast cancer patients stratified by hormone receptor status

Androgen receptor expression predicts different clinical outcomes for breast cancer patients stratified by hormone receptor status

https://doi.org/10.18632/oncotarget.9778

He-Sheng Jiang, Xia-Ying Kuang, Wei-Li Sun, Yan Xu, Yi-Zi Zheng, Yi-Rong Liu, Guan-Tian Lang, Feng Qiao, Xin Hu,  and Zhi-Ming Shao
41285-41293
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mesenchymal stem cells promote pancreatic adenocarcinoma cells invasion by transforming growth factor-β1 induced epithelial-mesenchymal transition

Mesenchymal stem cells promote pancreatic adenocarcinoma cells invasion by transforming growth factor-β1 induced epithelial-mesenchymal transition

https://doi.org/10.18632/oncotarget.9319

Hai-Sen Zhou, Xiao-Fang Su, Xing-Li Fu, Guo-Zhong Wu, Kun-Lun Luo, Zheng Fang, Feng Yu, Hong Liu, Hong-Juan Hu, Liu-Sheng Chen, Bing Cai,  and Zhi-Qiang Tian
41294-41305
Abstract  |  PDF  |  HTML  |  Order a Reprint

microRNA-374a suppresses colon cancer progression by directly reducing CCND1 to inactivate the PI3K/AKT pathway

microRNA-374a suppresses colon cancer progression by directly reducing CCND1 to inactivate the PI3K/AKT pathway

https://doi.org/10.18632/oncotarget.9320

Yiyu Chen, Jingwen Jiang, Mengyang Zhao, Xiaojun Luo, Zixi Liang, Yan Zhen, Qiaofen Fu, Xiaojie Deng, Xian Lin, Libo Li, Rongcheng Luo, Zhen Liu,  and Weiyi Fang
41306-41319
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Distinct mechanisms contribute to acquired cisplatin resistance of urothelial carcinoma cells

Distinct mechanisms contribute to acquired cisplatin resistance of urothelial carcinoma cells

https://doi.org/10.18632/oncotarget.9321

Annika Höhn, Katharina Krüger, Margaretha A. Skowron, Stefanie Bormann, Lena Schumacher, Wolfgang A. Schulz, Michèle J. Hoffmann, Günter Niegisch,  and Gerhard Fritz
41320-41335
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

rs965513 polymorphism as a common risk marker is associated with papillary thyroid cancer

rs965513 polymorphism as a common risk marker is associated with papillary thyroid cancer

https://doi.org/10.18632/oncotarget.9324

Fang Wang, Dehui Yan, Xu Ji, Jun Han, Meijun Chen, Hong Qiao,  and Shaojun Zhang
41336-41345
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Isolation, identification, and characterization of novel nanovesicles

Isolation, identification, and characterization of novel nanovesicles

https://doi.org/10.18632/oncotarget.9325

Huang-Ge Zhang, Pengxiao Cao, Yun Teng, Xin Hu, Qilong Wang, Ashish S. Yeri, Xiaoying Zhuang, Abhilash Samykutty, Jingyao Mu, Zhong-Bin Deng, Lifeng Zhang, James A. Mobley, Jun Yan, Kendall Van Keuren-Jensen,  and Donald Miller
41346-41362
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

COTI-2, a novel small molecule that is active against multiple human cancer cell lines in vitro and in vivo

COTI-2, a novel small molecule that is active against multiple human cancer cell lines in vitro and in vivo

https://doi.org/10.18632/oncotarget.9133

Kowthar Y. Salim, Saman Maleki Vareki, Wayne R. Danter, Serban San-Marina,  and James Koropatnick
41363-41379
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The prognostic role of RANK SNP rs34945627 in breast cancer patients with bone metastases

The prognostic role of RANK SNP rs34945627 in breast cancer patients with bone metastases

https://doi.org/10.18632/oncotarget.9356

Arlindo Ferreira, Irina Alho, Inês Vendrell, Marta Melo, Raquel Brás, Ana Lúcia Costa, Ana Rita Sousa, André Mansinho, Catarina Abreu, Catarina Pulido, Daniela Macedo, Teresa Pacheco, Lurdes Correia, Luis Costa,  and Sandra Casimiro
41380-41389
Abstract  |  PDF  |  HTML  |  Order a Reprint

Inhibitor of Apoptosis Proteins (IAPs) are commonly dysregulated in GIST and can be pharmacologically targeted to enhance the pro-apoptotic activity of imatinib

Inhibitor of Apoptosis Proteins (IAPs) are commonly dysregulated in GIST and can be pharmacologically targeted to enhance the pro-apoptotic activity of imatinib

https://doi.org/10.18632/oncotarget.9159

Johanna Falkenhorst, Susanne Grunewald, Thomas Mühlenberg, Adrian Marino-Enriquez, Anna-Carina Reis, Christopher Corless, Michael Heinrich, Jürgen Treckmann, Lars Erik Podleska, Martin Schuler, Jonathan Alfred Fletcher,  and Sebastian Bauer
41390-41403
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mitochondrial GRIM-19 as a potential therapeutic target for STAT3-dependent carcinogenesis of gastric cancer

Mitochondrial GRIM-19 as a potential therapeutic target for STAT3-dependent carcinogenesis of gastric cancer

https://doi.org/10.18632/oncotarget.9167

Yi Huang, Meihua Yang, Huajian Hu, Xiaodong Zhao, Liming Bao, Daochao Huang, Lihua Song,  and Yang Li
41404-41420
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Apigenin inhibits NF-κB and Snail signaling, EMT and metastasis in human hepatocellular carcinoma

Apigenin inhibits NF-κB and Snail signaling, EMT and metastasis in human hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9404

Yuan Qin, Dong Zhao, Hong-gang Zhou, Xing-hui Wang, Wei-long Zhong, Shuang Chen, Wen-guang Gu, Wei Wang, Chun-hong Zhang, Yan-rong Liu, Hui-juan Liu, Qiang Zhang, Yuan-qiang Guo, Tao Sun,  and Cheng Yang
41421-41431
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Endoplasmic reticulum stress and IRE-1 signaling cause apoptosis in colon cancer cells in response to andrographolide treatment

Endoplasmic reticulum stress and IRE-1 signaling cause apoptosis in colon cancer cells in response to andrographolide treatment

https://doi.org/10.18632/oncotarget.9180

Aditi Banerjee, Hafiz Ahmed, Peixin Yang, Steven J. Czinn,  and Thomas G. Blanchard
41432-41444
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RhoE/ROCK2 regulates chemoresistance through NF-κB/IL-6/ STAT3 signaling in hepatocellular carcinoma

RhoE/ROCK2 regulates chemoresistance through NF-κB/IL-6/ STAT3 signaling in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9441

Wei Ma, Karen Man-Fong Sze, Lo Kong Chan, Joyce Man-Fong Lee, Larry Lai Wei, Chun-Ming Wong, Terence Kin-Wah Lee, Carmen Chak-Lui Wong,  and Irene Oi-Lin Ng
41445-41459
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The mechanisms of malic enzyme 2 in the tumorigenesis of human gliomas

The mechanisms of malic enzyme 2 in the tumorigenesis of human gliomas

https://doi.org/10.18632/oncotarget.9190

Chiao-Pei Cheng, Li-Chun Huang, Yung-Lung Chang, Ching-Hsuan Hsieh, Shih-Ming Huang,  and Dueng-Yuan Hueng
41460-41472
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Metastatic site-specific polarization of macrophages in intracranial breast cancer metastases

Metastatic site-specific polarization of macrophages in intracranial breast cancer metastases

https://doi.org/10.18632/oncotarget.9445

Nora Rippaus, David Taggart, Jennifer Williams, Tereza Andreou, Heiko Wurdak, Krzysztof Wronski,  and Mihaela Lorger
41473-41487
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Hypoxia regulates TRAIL sensitivity of colorectal cancer cells through mitochondrial autophagy

Hypoxia regulates TRAIL sensitivity of colorectal cancer cells through mitochondrial autophagy

https://doi.org/10.18632/oncotarget.9206

Gertrud Knoll, Sebastian Bittner, Maria Kurz, Jonathan Jantsch,  and Martin Ehrenschwender
41488-41504
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MiR-146b-5p overexpression attenuates stemness and radioresistance of glioma stem cells by targeting HuR/lincRNA-p21/β-catenin pathway

MiR-146b-5p overexpression attenuates stemness and radioresistance of glioma stem cells by targeting HuR/lincRNA-p21/β-catenin pathway

https://doi.org/10.18632/oncotarget.9214

Wei Yang, Hongquan Yu, Yueming Shen, Yingying Liu, Zhanshan Yang,  and Ting Sun
41505-41526
Abstract  |  PDF  |  HTML  |  Order a Reprint

Moderate and strong static magnetic fields directly affect EGFR kinase domain orientation to inhibit cancer cell proliferation

Moderate and strong static magnetic fields directly affect EGFR kinase domain orientation to inhibit cancer cell proliferation

https://doi.org/10.18632/oncotarget.9479

Lei Zhang, Jihao Wang, HongLei Wang, Wenchao Wang, Zhiyuan Li, Juanjuan Liu, Xingxing Yang, Xinmiao Ji, Yan Luo, Chen Hu, Yubin Hou, Qianqian He, Jun Fang, Junfeng Wang, Qingsong Liu, Guohui Li, Qingyou Lu,  and Xin Zhang
41527-41539
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

EZH2 promotes colorectal cancer stem-like cell expansion by activating p21cip1-Wnt/β-catenin signaling

EZH2 promotes colorectal cancer stem-like cell expansion by activating p21cip1-Wnt/β-catenin signaling

https://doi.org/10.18632/oncotarget.9236

Jian-Fang Chen, Xi Luo, Li-Sha Xiang, Hong-Tao Li, Lin Zha, Ni Li, Jian-Ming He, Gan-Feng Xie, Xiong Xie,  and Hou-Jie Liang
41540-41558
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Radiation-enhanced therapeutic targeting of galectin-1 enriched malignant stroma in triple negative breast cancer

Radiation-enhanced therapeutic targeting of galectin-1 enriched malignant stroma in triple negative breast cancer

https://doi.org/10.18632/oncotarget.9490

Meenakshi Upreti, Amar Jyoti, Sara E. Johnson, Elden P. Swindell, Dana Napier, Pallavi Sethi, Ryan Chan, Jonathan M. Feddock, Heidi L. Weiss, Thomas V. O’Halloran,  and B. Mark Evers
41559-41574
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Plasma microRNA panels to diagnose pancreatic cancer: Results from a multicenter study

Plasma microRNA panels to diagnose pancreatic cancer: Results from a multicenter study

https://doi.org/10.18632/oncotarget.9491

Zhe Cao, Chang Liu, Jianwei Xu, Lei You, Chunyou Wang, Wenhui Lou, Bei Sun, Yi Miao, Xubao Liu, Xiaowo Wang, Taiping Zhang,  and Yupei Zhao
41575-41583
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Anti-metastatic potential of somatostatin analog SOM230: Indirect pharmacological targeting of pancreatic cancer-associated fibroblasts

Anti-metastatic potential of somatostatin analog SOM230: Indirect pharmacological targeting of pancreatic cancer-associated fibroblasts

https://doi.org/10.18632/oncotarget.9296

Siham Moatassim-Billah, Camille Duluc, Rémi Samain, Christine Jean, Aurélie Perraud, Emilie Decaup, Stéphanie Cassant-Sourdy, Youssef Bakri, Janick Selves, Herbert Schmid, Yvan Martineau, Muriel Mathonnet, Stéphane Pyronnet,  and Corinne Bousquet
41584-41598
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Speed of leukemia development and genetic diversity in xenograft models of T cell acute lymphoblastic leukemia

Speed of leukemia development and genetic diversity in xenograft models of T cell acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.9313

Sandrine Poglio, Daniel Lewandowski, Julien Calvo, Aurélie Caye, Audrey Gros, Elodie Laharanne, Thierry Leblanc, Judith Landman-Parker, André Baruchel, Jean Soulier, Paola Ballerini, Emmanuelle Clappier,  and Françoise Pflumio
41599-41611
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Morphoproteomics and biomedical analytics confirm the mTORC2/Akt pathway as a resistance signature and activated ERK and STAT3 as concomitant prosurvival/antiapoptotic pathways in metastatic renal cell carcinoma (RCC) progressing on rapalogs: Pathogenesis and therapeutic options

Morphoproteomics and biomedical analytics confirm the mTORC2/Akt pathway as a resistance signature and activated ERK and STAT3 as concomitant prosurvival/antiapoptotic pathways in metastatic renal cell carcinoma (RCC) progressing on rapalogs: Pathogenesis and therapeutic options

https://doi.org/10.18632/oncotarget.9508

Robert E. Brown, Jamie Buryanek, Varaha S. Tammisetti, Mary F. McGuire,  and Keri Csencsits-Smith
41612-41621
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Reactive oxygen species formation and bystander effects in gradient irradiation on human breast cancer cells

Reactive oxygen species formation and bystander effects in gradient irradiation on human breast cancer cells

https://doi.org/10.18632/oncotarget.9517

Dongqing Zhang, Tingyang Zhou, Feng He, Yi Rong, Shin Hee Lee, Shiyong Wu,  and Li Zuo
41622-41636
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Altered glutamine metabolism in platinum resistant ovarian cancer

Altered glutamine metabolism in platinum resistant ovarian cancer

https://doi.org/10.18632/oncotarget.9317

Chantelle D. Hudson, Alyssa Savadelis, Anil Belur Nagaraj, Peronne Joseph, Stefanie Avril, Analisa DiFeo,  and Norbert Avril
41637-41649
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Lnc-CC3 increases metastasis in cervical cancer by increasing Slug expression

Lnc-CC3 increases metastasis in cervical cancer by increasing Slug expression

https://doi.org/10.18632/oncotarget.9519

Binyuan Jiang, Ruili Sun, Shujuan Fang, Changfei Qin, Xi Pan, Li Peng, Yuehui Li,  and Guancheng Li
41650-41661
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Functional TRAIL receptors in monocytes and tumor-associated macrophages: A possible targeting pathway in the tumor microenvironment

Functional TRAIL receptors in monocytes and tumor-associated macrophages: A possible targeting pathway in the tumor microenvironment

https://doi.org/10.18632/oncotarget.9340

Manuela Liguori, Chiara Buracchi, Fabio Pasqualini, Francesca Bergomas, Samantha Pesce, Marina Sironi, Fabio Grizzi, Alberto Mantovani, Cristina Belgiovine,  and Paola Allavena
41662-41676
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Establishment of a multimarker qPCR panel for the molecular characterization of circulating tumor cells in blood samples of metastatic breast cancer patients during the course of palliative treatment

Establishment of a multimarker qPCR panel for the molecular characterization of circulating tumor cells in blood samples of metastatic breast cancer patients during the course of palliative treatment

https://doi.org/10.18632/oncotarget.9528

Maren Bredemeier, Philippos Edimiris, Mitra Tewes, Pawel Mach, Bahriye Aktas, Doreen Schellbach, Jenny Wagner, Rainer Kimmig,  and Sabine Kasimir-Bauer
41677-41690
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MET exon 14 skipping defines a unique molecular class of non-small cell lung cancer

MET exon 14 skipping defines a unique molecular class of non-small cell lung cancer

https://doi.org/10.18632/oncotarget.9541

Difan Zheng, Rui Wang, Ting Ye, Su Yu, Haichuan Hu, Xuxia Shen, Yuan Li, Hongbin Ji, Yihua Sun,  and Haiquan Chen
41691-41702
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Identification and validation of AIB1 and EIF5A2 for noninvasive detection of bladder cancer in urine samples

Identification and validation of AIB1 and EIF5A2 for noninvasive detection of bladder cancer in urine samples

https://doi.org/10.18632/oncotarget.9406

Bang-Fen Zhou, Jin-Huan Wei, Zhen-Hua Chen, Pei Dong, Ying-Rong Lai, Yong Fang, Hui-Ming Jiang, Jun Lu, Fang-Jian Zhou, Dan Xie, Jun-Hang Luo,  and Wei Chen
41703-41714
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Associations between genetic variants located in mature microRNAs and risk of lung cancer

Associations between genetic variants located in mature microRNAs and risk of lung cancer

https://doi.org/10.18632/oncotarget.9566

Dengrui Li, Guiyun Zhu, Hongqin Di, Hui Li, Xinyan Liu, Min Zhao, Zhihua Zhang,  and Yonghui Yang
41715-41724
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Inhibition of chronic lymphocytic leukemia progression by full-length chromogranin A and its N-terminal fragment in mouse models

Inhibition of chronic lymphocytic leukemia progression by full-length chromogranin A and its N-terminal fragment in mouse models

https://doi.org/10.18632/oncotarget.9407

Mimma Bianco, Anna Gasparri, Luca Generoso, Emma Assi, Barbara Colombo, Lydia Scarfò, Maria T.S. Bertilaccio, Cristina Scielzo, Pamela Ranghetti, Eleonora Dondossola, Maurilio Ponzoni, Federico Caligaris-Cappio, Paolo Ghia,  and Angelo Corti
41725-41736
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of prognostic biomarkers in glioblastoma using a long non-coding RNA-mediated, competitive endogenous RNA network

Identification of prognostic biomarkers in glioblastoma using a long non-coding RNA-mediated, competitive endogenous RNA network

https://doi.org/10.18632/oncotarget.9569

Yuze Cao, Peng Wang, Shangwei Ning, Wenbiao Xiao, Bo Xiao,  and Xia Li
41737-41747
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GLK/MAP4K3 overexpression associates with recurrence risk for non-small cell lung cancer

GLK/MAP4K3 overexpression associates with recurrence risk for non-small cell lung cancer

https://doi.org/10.18632/oncotarget.9410

Chung-Ping Hsu, Huai-Chia Chuang, Ming-Ching Lee, Hsiao-Hui Tsou, Li-Wen Lee, Ju-Pi Li,  and Tse-Hua Tan
41748-41757
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High serum haptoglobin level is associated with tumor progression and predicts poor prognosis in non-small cell lung cancer

High serum haptoglobin level is associated with tumor progression and predicts poor prognosis in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.9676

Jianjun Lu, Yanhong Wang, Miansheng Yan, Pinning Feng, Linjing Yuan, Yuesu Cai, Xin Xia, Min Liu, Jinmei Luo,  and Laisheng Li
41758-41766
Abstract  |  PDF  |  HTML  |  Order a Reprint

The posterior HOXD locus: Its contribution to phenotype and malignancy of Ewing sarcoma

The posterior HOXD locus: Its contribution to phenotype and malignancy of Ewing sarcoma

https://doi.org/10.18632/oncotarget.9702

Kristina von Heyking, Laura Roth, Miriam Ertl, Oxana Schmidt, Julia Calzada- Wack, Frauke Neff, Elizabeth R. Lawlor, Stefan Burdach,  and Günther H.S. Richter
41767-41780
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Luminal STAT5 mediates H2AX promoter activity in distinct population of basal mammary epithelial cells

Luminal STAT5 mediates H2AX promoter activity in distinct population of basal mammary epithelial cells

https://doi.org/10.18632/oncotarget.9718

Moshe Reichenstein, Gat Rauner, Shenhav Kfir, Tatiana Kisliouk,  and Itamar Barash
41781-41797
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Regulation of HK2 expression through alterations in CpG methylation of the HK2 promoter during progression of hepatocellular carcinoma

Regulation of HK2 expression through alterations in CpG methylation of the HK2 promoter during progression of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9723

Hyun Gyu Lee, Hyemi Kim, Taekwon Son, Youngtae Jeong, Seung Up Kim, Seung Myung Dong, Young Nyun Park, Jong Doo Lee, Jae Myun Lee,  and Jeon Han Park
41798-41810
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination

Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination

https://doi.org/10.18632/oncotarget.9619

Yoon Kyung Jeon, Chung Kwon Kim, Jaemoon Koh, Doo Hyun Chung,  and Geun-Hyoung Ha
41811-41824
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Characterization and use of HapT1-derived homologous tumors as a preclinical model to evaluate therapeutic efficacy of drugs against pancreatic tumor desmoplasia

Characterization and use of HapT1-derived homologous tumors as a preclinical model to evaluate therapeutic efficacy of drugs against pancreatic tumor desmoplasia

https://doi.org/10.18632/oncotarget.9729

Sujit Suklabaidya, Biswajit Das, Syed Azmal Ali, Sumeet Jain, Sharada Swaminathan, Ashok K. Mohanty, Susen K. Panda, Pujarini Dash, Subhankar Chakraborty, Surinder K. Batra,  and Shantibhusan Senapati
41825-41842
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel arylbenzofuran induces cervical cancer cell apoptosis and G1/S arrest through ERK-mediated Cdk2/cyclin-A signaling pathway

A novel arylbenzofuran induces cervical cancer cell apoptosis and G1/S arrest through ERK-mediated Cdk2/cyclin-A signaling pathway

https://doi.org/10.18632/oncotarget.9731

Pinghong Ming, Ting Cai, Jin Li, Yong Ning, Shengao Xie, Tao Tao,  and Faqing Tang
41843-41856
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of ALK1 signaling with dalantercept combined with VEGFR TKI leads to tumor stasis in renal cell carcinoma

Inhibition of ALK1 signaling with dalantercept combined with VEGFR TKI leads to tumor stasis in renal cell carcinoma

https://doi.org/10.18632/oncotarget.9621

Xiaoen Wang, Nicolas Solban, Prateek Khanna, Marcella Callea, Jiaxi Song, David C. Alsop, R. Scott Pearsall, Michael B. Atkins, James W. Mier, Sabina Signoretti, Marat Alimzhanov, Ravi Kumar, Manoj K. Bhasin,  and Rupal S. Bhatt
41857-41869
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Viral oncomiR spreading between B and T cells is employed by Kaposi's sarcoma herpesvirus to induce non-cell-autonomous target gene regulation

Viral oncomiR spreading between B and T cells is employed by Kaposi's sarcoma herpesvirus to induce non-cell-autonomous target gene regulation

https://doi.org/10.18632/oncotarget.9627

Nir Rainy, Morad Zayoud, Yoel Kloog, Oded Rechavi,  and Itamar Goldstein
41870-41884
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TACC3 promotes colorectal cancer tumourigenesis and correlates with poor prognosis

TACC3 promotes colorectal cancer tumourigenesis and correlates with poor prognosis

https://doi.org/10.18632/oncotarget.9628

Yong Du, Lili Liu, Chenliang Wang, Bohua Kuang, Shumei Yan, Aijun Zhou, Chuangyu Wen, Junxiong Chen, Yue Wu, Xiangling Yang, Guokai Feng, Bin Liu, Aikichi Iwamoto, Musheng Zeng, Jianping Wang, Xing Zhang,  and Huanliang Liu
41885-41897
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Altered splicing leads to reduced activation of CPEB3 in high-grade gliomas

Altered splicing leads to reduced activation of CPEB3 in high-grade gliomas

https://doi.org/10.18632/oncotarget.9735

Magdalena Skubal, Gerrit H. Gielen, Anke Waha, Marco Gessi, Lech Kaczmarczyk, Gerald Seifert, Dorothee Freihoff, Johannes Freihoff, Torsten Pietsch, Matthias Simon, Martin Theis, Christian Steinhäuser,  and Andreas Waha
41898-41912
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Phospholipid scramblase 1 as a critical node at the crossroad between autophagy and apoptosis in mantle cell lymphoma

Phospholipid scramblase 1 as a critical node at the crossroad between autophagy and apoptosis in mantle cell lymphoma

https://doi.org/10.18632/oncotarget.9630

Katy Mastorci, Barbara Montico, Damiana A. Faè, Luca Sigalotti, Maurilio Ponzoni, Giorgio Inghirami, Riccardo Dolcetti,  and Jessica Dal Col
41913-41928
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma

Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma

https://doi.org/10.18632/oncotarget.9740

Tiziana de Cristofaro, Tina Di Palma, Amata Amy Soriano, Antonella Monticelli, Ornella Affinito, Sergio Cocozza,  and Mariastella Zannini
41929-41947
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer

Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer

https://doi.org/10.18632/oncotarget.9632

Artur Mezheyeuski, Maja Bradic Lindh, Tormod Kyrre Guren, Anca Dragomir, Per Pfeiffer, Elin H. Kure, Tone Ikdahl, Eva Skovlund, Sara Corvigno, Carina Strell, Kristian Pietras, Fredrik Ponten, Jan Mulder, Camilla Qvortrup, Anna Portyanko, Kjell Magne Tveit, Bengt Glimelius, Halfdan Sorbye,  and Arne Östman
41948-41958
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comparative evaluation of three proliferation markers, Ki-67, TOP2A, and RacGAP1, in bronchopulmonary neuroendocrine neoplasms: Issues and prospects

Comparative evaluation of three proliferation markers, Ki-67, TOP2A, and RacGAP1, in bronchopulmonary neuroendocrine neoplasms: Issues and prospects

https://doi.org/10.18632/oncotarget.9747

Elisa Neubauer, Ralph M. Wirtz, Daniel Kaemmerer, Maria Athelogou, Lydia Schmidt, Jörg Sänger,  and Amelie Lupp
41959-41973
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The inflammatory/cancer-related IL-6/STAT3/NF-κB positive feedback loop includes AUF1 and maintains the active state of breast myofibroblasts

The inflammatory/cancer-related IL-6/STAT3/NF-κB positive feedback loop includes AUF1 and maintains the active state of breast myofibroblasts

https://doi.org/10.18632/oncotarget.9633

Siti-Fauziah Hendrayani, Bothaina Al-Harbi, Mysoon M. Al-Ansari, Gabriela Silva,  and Abdelilah Aboussekhra
41974-41985
Abstract  |  PDF  |  HTML  |  Order a Reprint

High expression of galectin-7 associates with poor overall survival in patients with non-metastatic clear-cell renal cell carcinoma

High expression of galectin-7 associates with poor overall survival in patients with non-metastatic clear-cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.9749

Jieti Wang, Yidong Liu, Yuanfeng Yang, Zhiying Xu, Guodong Zhang, Zheng Liu, Hangcheng Fu, Zewei Wang, Haiou Liu,  and Jiejie Xu
41986-41995
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Validation study for the hypothesis of internal mammary sentinel lymph node lymphatic drainage in breast cancer

Validation study for the hypothesis of internal mammary sentinel lymph node lymphatic drainage in breast cancer

https://doi.org/10.18632/oncotarget.9634

Bin-Bin Cong, Peng-Fei Qiu, Yan-Bing Liu, Tong Zhao, Peng Chen, Xiao-Shan Cao, Chun-Jian Wang, Zhao-Peng Zhang, Xiao Sun, Jin-Ming Yu,  and Yong-Sheng Wang
41996-42006
Abstract  |  PDF  |  HTML  |  Order a Reprint

Ubiquitin specific peptidase 21 regulates interleukin-8 expression, stem-cell like property of human renal cell carcinoma

Ubiquitin specific peptidase 21 regulates interleukin-8 expression, stem-cell like property of human renal cell carcinoma

https://doi.org/10.18632/oncotarget.9751

Liang Peng, Yi Hu, Demeng Chen, Shunchang Jiao,  and Shengkun Sun
42007-42016
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Folate-targeted star-shaped cationic copolymer co-delivering docetaxel and MMP-9 siRNA for nasopharyngeal carcinoma therapy

Folate-targeted star-shaped cationic copolymer co-delivering docetaxel and MMP-9 siRNA for nasopharyngeal carcinoma therapy

https://doi.org/10.18632/oncotarget.9771

Tao Liu, Xidong Wu, Yigang Wang, Tao Zhang, Ting Wu, Fang Liu, Wansong Wang, Gang Jiang,  and Minqiang Xie
42017-42030
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IL-8 signaling is involved in resistance of lung carcinoma cells to erlotinib

IL-8 signaling is involved in resistance of lung carcinoma cells to erlotinib

https://doi.org/10.18632/oncotarget.9662

Romaine I. Fernando, Duane H. Hamilton, Charli Dominguez, Justin M. David, Kristen K. McCampbell,  and Claudia Palena
42031-42044
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel predictive model based on preoperative blood neutrophil-to-lymphocyte ratio for survival prognosis in patients with gastric neuroendocrine neoplasms

A novel predictive model based on preoperative blood neutrophil-to-lymphocyte ratio for survival prognosis in patients with gastric neuroendocrine neoplasms

https://doi.org/10.18632/oncotarget.9805

Long-Long Cao, Jun Lu, Jian-Xian Lin, Chao-Hui Zheng, Ping Li, Jian-Wei Xie, Jia-Bin Wang, Qi-Yue Chen, Mi Lin, Ru-Hong Tu,  and Chang-Ming Huang
42045-42058
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The reverse-mode NCX1 activity inhibitor KB-R7943 promotes prostate cancer cell death by activating the JNK pathway and blocking autophagic flux

The reverse-mode NCX1 activity inhibitor KB-R7943 promotes prostate cancer cell death by activating the JNK pathway and blocking autophagic flux

https://doi.org/10.18632/oncotarget.9806

Zhou Long, BaiJun Chen, Qian Liu, Jiang Zhao, ZhenXing Yang, XingYou Dong, LiuBin Xia, ShengQuan Huang, XiaoYan Hu, Bo Song,  and LongKun Li
42059-42070
Abstract  |  PDF  |  HTML  |  Order a Reprint

Presence of TMPRSS2-ERG is associated with alterations of the metabolic profile in human prostate cancer

Presence of TMPRSS2-ERG is associated with alterations of the metabolic profile in human prostate cancer

https://doi.org/10.18632/oncotarget.9817

Ailin Falkmo Hansen, Elise Sandsmark, Morten Beck Rye, Alan J. Wright, Helena Bertilsson, Elin Richardsen, Trond Viset, Anna M. Bofin, Anders Angelsen, Kirsten M. Selnæs, Tone Frost Bathen,  and May-Britt Tessem
42071-42085
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Opposite prognostic roles of HIF1α and HIF2α expressions in bone metastatic clear cell renal cell cancer

Opposite prognostic roles of HIF1α and HIF2α expressions in bone metastatic clear cell renal cell cancer

https://doi.org/10.18632/oncotarget.9669

Attila Szendrői, A. Marcell Szász, Magdolna Kardos, Anna-Mária Tőkés, Roni Idan, Miklós Szűcs, Janina Kulka, Péter Nyirády, Miklós Szendrői, Zoltán Szállási, Balázs Győrffy,  and József Tímár
42086-42098
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Lack of interferon-γ receptor results in a microenvironment favorable for intestinal tumorigenesis

Lack of interferon-γ receptor results in a microenvironment favorable for intestinal tumorigenesis

https://doi.org/10.18632/oncotarget.9867

Caibo Zhang, Dong Hou, Haifeng Wei, Minnan Zhao, Lin Yang, Qiao Liu, Xiyu Zhang, Yaoqin Gong,  and Changshun Shao
42099-42109
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pharmacological activation of FOXO3 suppresses triple-negative breast cancer in vitro and in vivo

Pharmacological activation of FOXO3 suppresses triple-negative breast cancer in vitro and in vivo

https://doi.org/10.18632/oncotarget.9881

See-Hyoung Park, Young Min Chung, Jessica Ma, Qin Yang, Jonathan S. Berek,  and Mickey C-T. Hu
42110-42125
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Niclosamide sensitizes triple-negative breast cancer cells to ionizing radiation in association with the inhibition of Wnt/β-catenin signaling

Niclosamide sensitizes triple-negative breast cancer cells to ionizing radiation in association with the inhibition of Wnt/β-catenin signaling

https://doi.org/10.18632/oncotarget.9704

Lina Yin, Yun Gao, Xuxia Zhang, Jing Wang, Defang Ding, Yaping Zhang, Junxiang Zhang,  and Honghong Chen
42126-42138
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Direct cell fate conversion of human somatic stem cells into cone and rod photoreceptor-like cells by inhibition of microRNA-203

Direct cell fate conversion of human somatic stem cells into cone and rod photoreceptor-like cells by inhibition of microRNA-203

https://doi.org/10.18632/oncotarget.9882

Soon Won Choi, Ji-Hee Shin, Jae-Jun Kim, Tae-Hoon Shin, Yoojin Seo, Hyung-Sik Kim,  and Kyung-Sun Kang
42139-42149
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression of oncofetal antigen glypican-3 associates significantly with poor prognosis in HBV-related hepatocellular carcinoma

Expression of oncofetal antigen glypican-3 associates significantly with poor prognosis in HBV-related hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9892

Li Wang, Liuhong Pan, Min Yao, Yin Cai, Zhizhen Dong,  and Dengfu Yao
42150-42158
Abstract  |  PDF  |  HTML  |  Order a Reprint

Estrogen receptor beta reduces colon cancer metastasis through a novel miR-205 - PROX1 mechanism

Estrogen receptor beta reduces colon cancer metastasis through a novel miR-205 - PROX1 mechanism

https://doi.org/10.18632/oncotarget.9895

Trang Nguyen-Vu, Jun Wang, Fahmi Mesmar, Srijita Mukhopadhyay, Ashish Saxena, Catherine W. McCollum, Jan-Åke Gustafsson, Maria Bondesson,  and Cecilia Williams
42159-42171
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TLR4/ROS/miRNA-21 pathway underlies lipopolysaccharide instructed primary tumor outgrowth in lung cancer patients

TLR4/ROS/miRNA-21 pathway underlies lipopolysaccharide instructed primary tumor outgrowth in lung cancer patients

https://doi.org/10.18632/oncotarget.9902

Xianqi Zhang, Chunhong Wang, Shan Shan, Xiyu Liu, Zhongmin Jiang,  and Tao Ren
42172-42182
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long noncoding RNA GAPLINC promotes invasion in colorectal cancer by targeting SNAI2 through binding with PSF and NONO

Long noncoding RNA GAPLINC promotes invasion in colorectal cancer by targeting SNAI2 through binding with PSF and NONO

https://doi.org/10.18632/oncotarget.9741

Peng Yang, Tao Chen, Zipeng Xu, Hua Zhu, Jie Wang,  and Zhenyu He
42183-42194
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Virus-stimulated neutrophils in the tumor microenvironment enhance T cell-mediated anti-tumor immunity

Virus-stimulated neutrophils in the tumor microenvironment enhance T cell-mediated anti-tumor immunity

https://doi.org/10.18632/oncotarget.9743

Chin Yang Chang, Jiayu A. Tai, Sumin Li, Tomoyuki Nishikawa,  and Yasufumi Kaneda
42195-42207
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long-term statin use in patients with lung cancer and dyslipidemia reduces the risk of death

Long-term statin use in patients with lung cancer and dyslipidemia reduces the risk of death

https://doi.org/10.18632/oncotarget.9906

Wen-Yen Huang, Chia-Hsiang Li, Cheng-Li Lin,  and Ji-An Liang
42208-42215
Abstract  |  PDF  |  HTML  |  Order a Reprint

Pooled analysis of genome-wide association studies of cervical intraepithelial neoplasia 3 (CIN3) identifies a new susceptibility locus

Pooled analysis of genome-wide association studies of cervical intraepithelial neoplasia 3 (CIN3) identifies a new susceptibility locus

https://doi.org/10.18632/oncotarget.9916

Dan Chen, Stefan Enroth, Han Liu, Yang Sun, Huibo Wang, Min Yu, Lian Deng, Shuhua Xu,  and Ulf Gyllensten
42216-42224
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hsa-miR-875-5p exerts tumor suppressor function through down-regulation of EGFR in colorectal carcinoma (CRC)

Hsa-miR-875-5p exerts tumor suppressor function through down-regulation of EGFR in colorectal carcinoma (CRC)

https://doi.org/10.18632/oncotarget.9944

Tiening Zhang, Xun Cai, Qi Li, Peng Xue, Zhixiao Chen, Xiao Dong,  and Ying Xue
42225-42240
Abstract  |  PDF  |  HTML  |  Order a Reprint

miR-145 promotes osteosarcoma growth by reducing expression of the transcription factor friend leukemia virus integration 1

miR-145 promotes osteosarcoma growth by reducing expression of the transcription factor friend leukemia virus integration 1

https://doi.org/10.18632/oncotarget.9948

Panfeng Wu, Jieyu Liang, Fang Yu, Zhengbing Zhou, Juyu Tang,  and Kanghua Li
42241-42251
Abstract  |  PDF  |  HTML  |  Order a Reprint

Mutation spectrum of TP53 gene predicts clinicopathological features and survival of gastric cancer

Mutation spectrum of TP53 gene predicts clinicopathological features and survival of gastric cancer

https://doi.org/10.18632/oncotarget.9770

Tomomitsu Tahara, Tomoyuki Shibata, Yasuyuki Okamoto, Jumpei Yamazaki, Tomohiko Kawamura, Noriyuki Horiguchi, Masaaki Okubo, Naoko Nakano, Takamitsu Ishizuka, Mitsuo Nagasaka, Yoshihito Nakagawa,  and Naoki Ohmiya
42252-42260
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miRNAs involved in LY6K and estrogen receptor α contribute to tamoxifen-susceptibility in breast cancer

miRNAs involved in LY6K and estrogen receptor α contribute to tamoxifen-susceptibility in breast cancer

https://doi.org/10.18632/oncotarget.9950

Ye Sol Kim, Sae Jeong Park, Yeon Seon Lee, Hyun Kyung Kong,  and Jong Hoon Park
42261-42273
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-181a suppresses parkin-mediated mitophagy and sensitizes neuroblastoma cells to mitochondrial uncoupler-induced apoptosis

MicroRNA-181a suppresses parkin-mediated mitophagy and sensitizes neuroblastoma cells to mitochondrial uncoupler-induced apoptosis

https://doi.org/10.18632/oncotarget.9786

Min Cheng, Lei Liu, Yuanzhi Lao, Weijie Liao, Meijian Liao, Xuan Luo, Jiangbin Wu, Weidong Xie, Yaou Zhang,  and Naihan Xu
42274-42287
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nuclearly translocated insulin-like growth factor 1 receptor phosphorylates histone H3 at tyrosine 41 and induces SNAI2 expression via Brg1 chromatin remodeling protein

Nuclearly translocated insulin-like growth factor 1 receptor phosphorylates histone H3 at tyrosine 41 and induces SNAI2 expression via Brg1 chromatin remodeling protein

https://doi.org/10.18632/oncotarget.9785

Dudi Warsito, Yingbo Lin, Ann-Christin Gnirck, Bita Sehat,  and Olle Larsson
42288-42302
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CHES-1-like, the ortholog of a non-obstructive azoospermia-associated gene, blocks germline stem cell differentiation by upregulating Dpp expression in Drosophila testis

CHES-1-like, the ortholog of a non-obstructive azoospermia-associated gene, blocks germline stem cell differentiation by upregulating Dpp expression in Drosophila testis

https://doi.org/10.18632/oncotarget.9789

Jun Yu, Yujuan Liu, Xiang Lan, Hao Wu, Yang Wen, Zuomin Zhou, Zhibin Hu, Jiahao Sha, Xuejiang Guo,  and Chao Tong
42303-42313
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Human induced pluripotent stem cell differentiation and direct transdifferentiation into corneal epithelial-like cells

Human induced pluripotent stem cell differentiation and direct transdifferentiation into corneal epithelial-like cells

https://doi.org/10.18632/oncotarget.9791

Artur Cieślar-Pobuda, Mehrdad Rafat, Viktoria Knoflach, Magdalena Skonieczna, Andrzej Hudecki, Andrzej Małecki, Elżbieta Urasińska, Seaid Ghavami,  and Marek J. Łos
42314-42329
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Increased serum levels of betatrophin in pancreatic cancer-associated diabetes

Increased serum levels of betatrophin in pancreatic cancer-associated diabetes

https://doi.org/10.18632/oncotarget.9815

Hendra Susanto, Ta-Yu Liu, Chang-Chiang Chen, Jerry D.T. Purnomo, Shu-Fan Chen,  and Chih-Hong Wang
42330-42339
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dual inhibition of ErbB1 and ErbB2 in cancer by recombinant human prolidase mutant hPEPD-G278D

Dual inhibition of ErbB1 and ErbB2 in cancer by recombinant human prolidase mutant hPEPD-G278D

https://doi.org/10.18632/oncotarget.9851

Lu Yang, Yun Li, Arup Bhattacharya,  and Yuesheng Zhang
42340-42352
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Glaucarubinone sensitizes KB cells to paclitaxel by inhibiting ABC transporters via ROS-dependent and p53-mediated activation of apoptotic signaling pathways

Glaucarubinone sensitizes KB cells to paclitaxel by inhibiting ABC transporters via ROS-dependent and p53-mediated activation of apoptotic signaling pathways

https://doi.org/10.18632/oncotarget.9865

Subburayan Karthikeyan, Sugeerappa Laxmanappa Hoti, Yasin Nazeer,  and Harsha Vasudev Hegde
42353-42373
Abstract  |  PDF  |  HTML  |  Order a Reprint

PNT2258, a novel deoxyribonucleic acid inhibitor, induces cell cycle arrest and apoptosis via a distinct mechanism of action: a new class of drug for non-Hodgkin's lymphoma

PNT2258, a novel deoxyribonucleic acid inhibitor, induces cell cycle arrest and apoptosis via a distinct mechanism of action: a new class of drug for non-Hodgkin's lymphoma

https://doi.org/10.18632/oncotarget.9872

Abdul Shukkur Ebrahim, Mustapha Kandouz, Allison Liddane, Hussam Sabbagh, Yuning Hou, Chunying Li,  and Ayad Al-Katib
42374-42384
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Treatment with the nitric oxide synthase inhibitor L-NAME provides a survival advantage in a mouse model of Kras mutation-positive, non-small cell lung cancer

Treatment with the nitric oxide synthase inhibitor L-NAME provides a survival advantage in a mouse model of Kras mutation-positive, non-small cell lung cancer

https://doi.org/10.18632/oncotarget.9874

Nicole L.K. Pershing, Chi-Fu J. Yang, MengMeng Xu,  and Christopher M. Counter
42385-42392
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PI3K-PTEN dysregulation leads to mTOR-driven upregulation of the core clock gene BMAL1 in normal and malignant epithelial cells

PI3K-PTEN dysregulation leads to mTOR-driven upregulation of the core clock gene BMAL1 in normal and malignant epithelial cells

https://doi.org/10.18632/oncotarget.9877

Camila S. Matsumoto, Luciana O. Almeida, Douglas M. Guimarães, Manoela D. Martins, Petros Papagerakis, Silvana Papagerakis, Andreia M. Leopoldino, Rogerio M. Castilho,  and Cristiane H. Squarize
42393-42407
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preclinical effects of CRLX101, an investigational camptothecin-containing nanoparticle drug conjugate, on treating glioblastoma multiforme via apoptosis and antiangiogenesis

Preclinical effects of CRLX101, an investigational camptothecin-containing nanoparticle drug conjugate, on treating glioblastoma multiforme via apoptosis and antiangiogenesis

https://doi.org/10.18632/oncotarget.9878

Chien-Ju Lin, Yi-Ling Lin, Frank Luh, Yun Yen,  and Ruei-Ming Chen
42408-42421
Abstract  |  PDF  |  HTML  |  Order a Reprint

Comprehensive analysis of long non-coding RNA expression profiles in hepatitis B virus-related hepatocellular carcinoma

Comprehensive analysis of long non-coding RNA expression profiles in hepatitis B virus-related hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9880

Xianli Gong, Wei Wei, Lan Chen, Zhi Xia,  and Chengbo Yu
42422-42430
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LncRNA HULC enhances epithelial-mesenchymal transition to promote tumorigenesis and metastasis of hepatocellular carcinoma via the miR-200a-3p/ZEB1 signaling pathway

LncRNA HULC enhances epithelial-mesenchymal transition to promote tumorigenesis and metastasis of hepatocellular carcinoma via the miR-200a-3p/ZEB1 signaling pathway

https://doi.org/10.18632/oncotarget.9883

Shi-Peng Li, Hai-Xu Xu, Yao Yu, Jin-Dan He, Zhen Wang, Yan-Jie Xu, Chang-Ying Wang, Hai-Ming Zhang, Rong-Xin Zhang, Jian-Jun Zhang, Zhi Yao,  and Zhong-Yang Shen
42431-42446
Abstract  |  PDF  |  HTML  |  Order a Reprint

Sensitizing mucoepidermoid carcinomas to chemotherapy by targeted disruption of cancer stem cells

Sensitizing mucoepidermoid carcinomas to chemotherapy by targeted disruption of cancer stem cells

https://doi.org/10.18632/oncotarget.9884

Douglas M. Guimarães, Luciana O. Almeida, Manoela D. Martins, Kristy A. Warner, Alan R. S. Silva, Pablo A. Vargas, Fabio D. Nunes, Cristiane H. Squarize, Jacques E. Nör,  and Rogerio M. Castilho
42447-42460
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-33a-3p suppresses cell migration and invasion by directly targeting PBX3 in human hepatocellular carcinoma

MicroRNA-33a-3p suppresses cell migration and invasion by directly targeting PBX3 in human hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9886

Shu-Yan Han, Hai-Bo Han, Xiu-Yun Tian, Hong Sun, Dong Xue, Can Zhao, Shan-Tong Jiang, Xi-Ran He, Wen-Xian Zheng, Jing Wang, Li-Na Pang, Xiao-Hong Li,  and Ping-Ping Li
42461-42473
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MR molecular imaging of tumors based on an optimal hTERT promoter tyrosinase expression system

MR molecular imaging of tumors based on an optimal hTERT promoter tyrosinase expression system

https://doi.org/10.18632/oncotarget.9888

Chuan Li, Chang-Jiang Hu, Bo Tang, Xin Yong, Gang Luo, Yu-Yun Wu, Su-Min Wang, Song-Tao Yu,  and Shi-Ming Yang
42474-42484
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Musashi-1 regulates AKT-derived IL-6 autocrinal/paracrinal malignancy and chemoresistance in glioblastoma

Musashi-1 regulates AKT-derived IL-6 autocrinal/paracrinal malignancy and chemoresistance in glioblastoma

https://doi.org/10.18632/oncotarget.9890

Hsiao-Yun Chen, Liang-Ting Lin, Mong-Lien Wang, Shu-Hsien Lee, Ming-Long Tsai, Chi-Chang Tsai, Wei-Hsiu Liu, Tzu-Chien Chen, Yi-Ping Yang, Yi-Yen Lee, Yuh-Lih Chang, Pin-I Huang, Yi-Wei Chen, Wen-Liang Lo, Shih-Hwa Chiou,  and Ming-Teh Chen
42485-42501
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic significance of stem cell-related marker expression and its correlation with histologic subtypes in lung adenocarcinoma

Prognostic significance of stem cell-related marker expression and its correlation with histologic subtypes in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.9894

Eunhyang Park, Soo Young Park, Ping-Li Sun, Yan Jin, Ji Eun Kim, Sanghoon Jheon, Kwhanmien Kim, Choon Taek Lee, Hyojin Kim,  and Jin-Haeng Chung
42502-42512
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Wnt/β-catenin pathway transactivates microRNA-150 that promotes EMT of colorectal cancer cells by suppressing CREB signaling

Wnt/β-catenin pathway transactivates microRNA-150 that promotes EMT of colorectal cancer cells by suppressing CREB signaling

https://doi.org/10.18632/oncotarget.9893

Yan-Hua Guo, Lu-Qin Wang, Bin Li, Hui Xu, Jian-Hua Yang, Li-Si Zheng, Peng Yu, Ai-Dong Zhou, Yin Zhang, Shu-Juan Xie, Zi-Rui Liang, Chen-Min Zhang, Hui Zhou,  and Liang-Hu Qu
42513-42526
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck

WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck

https://doi.org/10.18632/oncotarget.9897

Vassiliki Saloura, Theodore Vougiouklakis, Makda Zewde, Kazuma Kiyotani, Jae-Hyun Park, Guimin Gao, Theodore Karrison, Mark Lingen, Yusuke Nakamura,  and Ryuji Hamamoto
42527-42538
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Emerging role of LOXL2 in the promotion of pancreas cancer metastasis

Emerging role of LOXL2 in the promotion of pancreas cancer metastasis

https://doi.org/10.18632/oncotarget.9918

Joon Seong Park, Ji-hae Lee, Yun Sun Lee, Jae Keun Kim, Seung Myung Dong,  and Dong Sup Yoon
42539-42552
Abstract  |  PDF  |  HTML  |  Order a Reprint

Aberrant methylation of MUC1 and MUC4 promoters are potential prognostic biomarkers for pancreatic ductal adenocarcinomas

Aberrant methylation of MUC1 and MUC4 promoters are potential prognostic biomarkers for pancreatic ductal adenocarcinomas

https://doi.org/10.18632/oncotarget.9924

Seiya Yokoyama, Michiyo Higashi, Sho Kitamoto, Monika Oeldorf, Uwe Knippschild, Marko Kornmann, Kosei Maemura, Hiroshi Kurahara, Edwin Wiest, Tomofumi Hamada, Ikumi Kitazono, Yuko Goto, Takashi Tasaki, Tsubasa Hiraki, Kazuhito Hatanaka, Yuko Mataki, Hiroki Taguchi, Shinichi Hashimoto, Surinder K. Batra, Akihide Tanimoto, Suguru Yonezawa,  and Michael A. Hollingsworth
42553-42565
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Down-regulation of Krüppel-like factor-4 by microRNA-135a-5p promotes proliferation and metastasis in hepatocellular carcinoma by transforming growth factor-β1

Down-regulation of Krüppel-like factor-4 by microRNA-135a-5p promotes proliferation and metastasis in hepatocellular carcinoma by transforming growth factor-β1

https://doi.org/10.18632/oncotarget.9934

Shanshan Yao, Chuan Tian, Youcheng Ding, Qingwang Ye, Yong Gao, Ning Yang,  and Qi Li
42566-42578
Abstract  |  PDF  |  HTML  |  Order a Reprint

Automatic segmentation software in locally advanced rectal cancer: READY (REsearch program in Auto Delineation sYstem)-RECTAL 02: prospective study

Automatic segmentation software in locally advanced rectal cancer: READY (REsearch program in Auto Delineation sYstem)-RECTAL 02: prospective study

https://doi.org/10.18632/oncotarget.9938

Maria A. Gambacorta, Luca Boldrini, Chiara Valentini, Nicola Dinapoli, Gian C. Mattiucci, Giuditta Chiloiro, Danilo Pasini, Stefania Manfrida, Nicola Caria, Bruce D. Minsky,  and Vincenzo Valentini
42579-42584
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tyrosine phosphorylation regulates ERβ ubiquitination, protein turnover, and inhibition of breast cancer

Tyrosine phosphorylation regulates ERβ ubiquitination, protein turnover, and inhibition of breast cancer

https://doi.org/10.18632/oncotarget.10018

Bin Yuan, Long Cheng, Kshama Gupta, Huai-Chin Chiang, Harshita B. Gupta, Gangadhara R. Sareddy, Degeng Wang, Kate Lathrop, Richard Elledge, Pei Wang, Stanton McHardy, Ratna Vadlamudi, Tyler J. Curiel, Yanfen Hu, Qinong Ye,  and Rong Li
42585-42597
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hepatocellular carcinoma cases with high levels of c-Raf-1 expression may benefit from postoperative adjuvant sorafenib after hepatic resection even with high risk of recurrence

Hepatocellular carcinoma cases with high levels of c-Raf-1 expression may benefit from postoperative adjuvant sorafenib after hepatic resection even with high risk of recurrence

https://doi.org/10.18632/oncotarget.3799

Jianyong Lei, Jinjing Zhong, Jincheng Hao, Zhengni Liu, Peng Zhang, Lixue Wu, Lunan Yan, Jinqiang Zhu, Yong Zeng, Bo Li, Tianfu Wen,  and Wentao Wang
42598-42607
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical Research Papers

Long-term clinical outcome in nasopharyngeal carcinoma patients with post-radiation persistently detectable plasma EBV DNA

Long-term clinical outcome in nasopharyngeal carcinoma patients with post-radiation persistently detectable plasma EBV DNA

https://doi.org/10.18632/oncotarget.9323

Wen-Yi Wang, Tian-Yun Lin, Chih-Wen Twu, Hsiao-Hui Tsou, Po-Ju Lin, Yi-Chun Liu, Jing-Wen Huang, He-Yuan Hsieh,  and Jin-Ching Lin
42608-42616
Abstract  |  PDF  |  HTML  |  Order a Reprint

NEURL rs6584555 and CAND2 rs4642101 contribute to postoperative atrial fibrillation: a prospective study among Chinese population

NEURL rs6584555 and CAND2 rs4642101 contribute to postoperative atrial fibrillation: a prospective study among Chinese population

https://doi.org/10.18632/oncotarget.9422

Tiemin Wei, Jingjing Song, Min Xu, Lingchun Lv, Chong Liu, Jiayi Shen,  and Ying Huang
42617-42624
Abstract  |  PDF  |  HTML  |  Order a Reprint

Phase I study of pemetrexed with sorafenib in advanced solid tumors

Phase I study of pemetrexed with sorafenib in advanced solid tumors

https://doi.org/10.18632/oncotarget.9434

Andrew Poklepovic, Sarah Gordon, Danielle A. Shafer, John D. Roberts, Prithviraj Bose, Charles E. Geyer Jr, William P. McGuire, Mary Beth Tombes, Ellen Shrader, Katie Strickler, Maria Quigley, Wen Wan, Maciej Kmieciak, H. Davis Massey, Laurence Booth, Richard G. Moran,  and Paul Dent
42625-42638
Abstract  |  PDF  |  HTML  |  Order a Reprint

Percutaneous computed tomography-guided cryoablation for recurrent retroperitoneal soft tissue sarcoma: a study of safety and efficacy

Percutaneous computed tomography-guided cryoablation for recurrent retroperitoneal soft tissue sarcoma: a study of safety and efficacy

https://doi.org/10.18632/oncotarget.9476

Wenzhe Fan, Lizhi Niu, Yu Wang, Yingqiang Zhang, Xuehua Yao, Guosheng Tan, Jianyong Yang,  and Jiaping Li
42639-42649
Abstract  |  PDF  |  HTML  |  Order a Reprint

The ratio of hemoglobin to red cell distribution width as a novel prognostic parameter in esophageal squamous cell carcinoma: a retrospective study from southern China

The ratio of hemoglobin to red cell distribution width as a novel prognostic parameter in esophageal squamous cell carcinoma: a retrospective study from southern China

https://doi.org/10.18632/oncotarget.9516

Peng Sun, Fei Zhang, Cui Chen, Xiwen Bi, Hang Yang, Xin An, Fenghua Wang,  and Wenqi Jiang
42650-42660
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reviews

Lipid-sensors, enigmatic-orphan and orphan nuclear receptors as therapeutic targets in breast-cancer

Lipid-sensors, enigmatic-orphan and orphan nuclear receptors as therapeutic targets in breast-cancer

https://doi.org/10.18632/oncotarget.7410

Enrico Garattini, Marco Bolis, Maurizio Gianni’, Gabriela Paroni, Maddalena Fratelli,  and Mineko Terao
42661-42682
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNAs mediated regulation of MAPK signaling pathways in chronic myeloid leukemia

MicroRNAs mediated regulation of MAPK signaling pathways in chronic myeloid leukemia

https://doi.org/10.18632/oncotarget.7977

Chiranjib Chakraborty, Ashish Ranjan Sharma, Bidhan Chandra Patra, Manojit Bhattacharya, Garima Sharma,  and Sang-Soo Lee
42683-42697
Abstract  |  PDF  |  HTML  |  Order a Reprint

Signal transducer and activator of transcription 3 in myeloid-derived suppressor cells: an opportunity for cancer therapy

Signal transducer and activator of transcription 3 in myeloid-derived suppressor cells: an opportunity for cancer therapy

https://doi.org/10.18632/oncotarget.8311

Inès Dufait, Elsa Van Valckenborgh, Eline Menu, David Escors, Mark De Ridder,  and Karine Breckpot
42698-42715
Abstract  |  PDF  |  HTML  |  Order a Reprint

The biology of DHX9 and its potential as a therapeutic target

The biology of DHX9 and its potential as a therapeutic target

https://doi.org/10.18632/oncotarget.8446

Teresa Lee,  and Jerry Pelletier
42716-42739
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cancer drug resistance: redox resetting renders a way

Cancer drug resistance: redox resetting renders a way

https://doi.org/10.18632/oncotarget.8600

Yuan Liu, Qifu Li, Li Zhou, Na Xie, Edouard C. Nice, Haiyuan Zhang, Canhua Huang,  and Yunlong Lei
42740-42761
Abstract  |  PDF  |  HTML  |  Order a Reprint

Utilization of animal models to investigate nonalcoholic steatohepatitis-associated hepatocellular carcinoma

Utilization of animal models to investigate nonalcoholic steatohepatitis-associated hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.8641

Jian Wu
42762-42776
Abstract  |  PDF  |  HTML  |  Order a Reprint

Osteoprotegerin rich tumor microenvironment: implications in breast cancer

Osteoprotegerin rich tumor microenvironment: implications in breast cancer

https://doi.org/10.18632/oncotarget.8658

Sudeshna Goswami,  and Neelam Sharma-Walia
42777-42791
Abstract  |  PDF  |  HTML  |  Interview with Dr. Neelam Sharma-Walia and Sudeshna Goswami  |  Order a Reprint

FOXM1 in sarcoma: role in cell cycle, pluripotency genes and stem cell pathways

FOXM1 in sarcoma: role in cell cycle, pluripotency genes and stem cell pathways

https://doi.org/10.18632/oncotarget.8669

Fergal C. Kelleher,  and Hazel O’Sullivan
42792-42804
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dysregulation and functional roles of miR-183-96-182 cluster in cancer cell proliferation, invasion and metastasis

Dysregulation and functional roles of miR-183-96-182 cluster in cancer cell proliferation, invasion and metastasis

https://doi.org/10.18632/oncotarget.8715

Yi Ma, A-Juan Liang, Yu-Ping Fan, Yi-Ran Huang, Xiao-Ming Zhao, Yun Sun,  and Xiang-Feng Chen
42805-42825
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GARP: a surface molecule of regulatory T cells that is involved in the regulatory function and TGF-β releasing

GARP: a surface molecule of regulatory T cells that is involved in the regulatory function and TGF-β releasing

https://doi.org/10.18632/oncotarget.8753

Liping Sun, Hao Jin,  and Hui Li
42826-42836
Abstract  |  PDF  |  HTML  |  Order a Reprint

Case Reports

Histological and molecular analysis of a progressive diffuse intrinsic pontine glioma and synchronous metastatic lesions: a case report

Histological and molecular analysis of a progressive diffuse intrinsic pontine glioma and synchronous metastatic lesions: a case report

https://doi.org/10.18632/oncotarget.10034

Javad Nazarian, Gary E. Mason, Cheng Ying Ho, Eshini Panditharatna, Madhuri Kambhampati, L. Gilbert Vezina, Roger J. Packer,  and Eugene I. Hwang
42837-42842
Abstract  |  PDF  |  HTML  |  Order a Reprint

Corrections

Correction: Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma

Correction: Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma

https://doi.org/10.18632/oncotarget.10404

Ambrish Kumar, Nadia Al-Sammarraie, Donald J. DiPette,  and Ugra S. Singh
42843
Correction  |  PDF


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