Oncotarget

Vol 7, No 25

June 21, 2016

View Archive »

Order a Reprint

About The Cover

Schematic overview of feedback activation of mTOR signaling upon PIM inhibition. See Brunen et al.

Table of Contents

Priority Research Papers

Intrinsic resistance to PIM kinase inhibition in AML through p38α-mediated feedback activation of mTOR signaling

Intrinsic resistance to PIM kinase inhibition in AML through p38α-mediated feedback activation of mTOR signaling

https://doi.org/10.18632/oncotarget.9822

Diede Brunen, María José García-Barchino, Disha Malani, Noorjahan Jagalur Basheer, Cor Lieftink, Roderick L. Beijersbergen, Astrid Murumägi, Kimmo Porkka, Maija Wolf, C. Michel Zwaan, Maarten Fornerod, Olli Kallioniemi, José Ángel Martínez-Climent,  and René Bernards
37407-37419
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers: Gerotarget (Focus on Aging)

MiR-23a-depressed autophagy is a participant in PUVA- and UVB-induced premature senescence

MiR-23a-depressed autophagy is a participant in PUVA- and UVB-induced premature senescence

https://doi.org/10.18632/oncotarget.9357

Jia-an Zhang, Bing-rong Zhou, Yang Xu, Xu Chen, Juan Liu, Maya Gozali, Di Wu, Zhi-qiang Yin,  and Dan Luo
37420-37435
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons

The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons

https://doi.org/10.18632/oncotarget.9545

Riccardo Vezzali, Stefan Christopher Weise, Nicole Hellbach, Venissa Machado, Stefanie Heidrich,  and Tanja Vogel
37436-37455
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers: Pathology

Caspase-8 inhibition represses initial human monocyte activation in septic shock model

Caspase-8 inhibition represses initial human monocyte activation in septic shock model

https://doi.org/10.18632/oncotarget.9648

Maria Jose Oliva-Martin, Luis Ignacio Sanchez-Abarca, Johanna Rodhe, Alejandro Carrillo-Jimenez, Pinelopi Vlachos, Antonio Jose Herrera, Albert Garcia-Quintanilla, Teresa Caballero-Velazquez, Jose Antonio Perez-Simon, Bertrand Joseph,  and Jose Luis Venero
37456-37470
Abstract  |  PDF  |  HTML  |  Order a Reprint

Osterix acetylation at K307 and K312 enhances its transcriptional activity and is required for osteoblast differentiation

Osterix acetylation at K307 and K312 enhances its transcriptional activity and is required for osteoblast differentiation

https://doi.org/10.18632/oncotarget.9650

Jianlei Lu, Shuang Qu, Bing Yao, Yuexin Xu, Yucui Jin, Kaikai Shi, Yifang Shui, Shiyang Pan, Li Chen,  and Changyan Ma
37471-37486
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers: Immunology

HCV-related liver and lymphoproliferative diseases: association with polymorphisms of IL28B and TLR2

HCV-related liver and lymphoproliferative diseases: association with polymorphisms of IL28B and TLR2

https://doi.org/10.18632/oncotarget.9303

Valli De Re, Mariangela De Zorzi, Laura Caggiari, Gianfranco Lauletta, Maria Lina Tornesello, Elisa Fognani, Marta Miorin, Vito Racanelli, Luca Quartuccio, Laura Gragnani, Sabino Russi, Fabio Pavone, Michela Ghersetti, Elena Garlatti Costa, Pietro Casarin, Riccardo Bomben, Cesare Mazzaro, Giancarlo Basaglia, Massimiliano Berretta, Emanuela Vaccher, Francesco Izzo, Franco Maria Buonaguro, Salvatore De Vita, Anna Linda Zignego, Paolo De Paoli,  and Riccardo Dolcetti
37487-37497
Abstract  |  PDF  |  HTML  |  Order a Reprint

TIM-4 is differentially expressed in the distinct subsets of dendritic cells in skin and skin-draining lymph nodes and controls skin Langerhans cell homeostasis

TIM-4 is differentially expressed in the distinct subsets of dendritic cells in skin and skin-draining lymph nodes and controls skin Langerhans cell homeostasis

https://doi.org/10.18632/oncotarget.9546

Xilin Zhang, Queping Liu, Jie Wang, Guihua Li, Matthew Weiland, Fu-Shin Yu, Qing-Sheng Mi, Jun Gu,  and Li Zhou
37498-37512
Abstract  |  PDF  |  HTML  |  Order a Reprint

Research Papers

Salmonella inhibits tumor angiogenesis by downregulation of vascular endothelial growth factor

Salmonella inhibits tumor angiogenesis by downregulation of vascular endothelial growth factor

https://doi.org/10.18632/oncotarget.7038

Dom-Gene Tu, Wen-Wei Chang, Song-Tao Lin, Chun-Yu Kuo, Yu-Tzu Tsao,  and Che-Hsin Lee
37513-37523
Abstract  |  PDF  |  HTML  |  Order a Reprint

Downregulation of miR-101 contributes to epithelial-mesenchymal transition in cisplatin resistance of NSCLC cells by targeting ROCK2

Downregulation of miR-101 contributes to epithelial-mesenchymal transition in cisplatin resistance of NSCLC cells by targeting ROCK2

https://doi.org/10.18632/oncotarget.6852

Zhiqiang Ye, Shengli Yin, Zhongzhen Su, Mingjun Bai, Haibo Zhang, Ziqing Hei,  and Songwang Cai
37524-37535
Abstract  |  PDF  |  HTML  |  Order a Reprint

c-Src/Cav1-dependent activation of the EGFR by Dsg2

c-Src/Cav1-dependent activation of the EGFR by Dsg2

https://doi.org/10.18632/oncotarget.7675

Andrew M. Overmiller, Kathleen P. McGuinn, Brett J. Roberts, Felicia Cooper, Donna M. Brennan-Crispi, Takahiro Deguchi, Sirkku Peltonen, James K. Wahl III,  and Mỹ G. Mahoney
37536-37555
Abstract  |  PDF  |  HTML  |  Order a Reprint

Nomogram based on systemic inflammatory response markers predicting the survival of patients with resectable gastric cancer after D2 gastrectomy

Nomogram based on systemic inflammatory response markers predicting the survival of patients with resectable gastric cancer after D2 gastrectomy

https://doi.org/10.18632/oncotarget.8788

Jianjun Liu, Qirong Geng, Shangxiang Chen, Xuechao Liu, Pengfei Kong, Zhiwei Zhou, Youqing Zhan,  and Dazhi Xu
37556-37565
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

NRAS germline variant G138R and multiple rare somatic mutations on APC in colorectal cancer patients in Taiwan by next generation sequencing

NRAS germline variant G138R and multiple rare somatic mutations on APC in colorectal cancer patients in Taiwan by next generation sequencing

https://doi.org/10.18632/oncotarget.8885

Pi-Yueh Chang, Jinn-Shiun Chen, Nai-Chung Chang, Shih-Cheng Chang, Mei-Chia Wang, Shu-Hui Tsai, Ying-Hao Wen, Wen-Sy Tsai, Err-Cheng Chan,  and Jang-Jih Lu
37566-37580
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The epithelial-mesenchymal transition phenotype of metastatic lymph nodes impacts the prognosis of esophageal squamous cell carcinoma patients

The epithelial-mesenchymal transition phenotype of metastatic lymph nodes impacts the prognosis of esophageal squamous cell carcinoma patients

https://doi.org/10.18632/oncotarget.9036

Jing Wen, Kong-Jia Luo, Qian-Wen Liu, Geng Wang, Mei-Fang Zhang, Xiu-Ying Xie, Hong Yang, Jian-Hua Fu,  and Yi Hu
37581-37588
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dosimetric impact of intermediate dose calculation for optimization convergence error

Dosimetric impact of intermediate dose calculation for optimization convergence error

https://doi.org/10.18632/oncotarget.7743

Byung Do Park, Tae Gyu Kim,  and Jong Eon Kim
37589-37598
Abstract  |  PDF  |  HTML  |  Order a Reprint

Angiogenesis genotyping in the selection of first-line treatment with either sunitinib or pazopanib for advanced renal cell carcinoma

Angiogenesis genotyping in the selection of first-line treatment with either sunitinib or pazopanib for advanced renal cell carcinoma

https://doi.org/10.18632/oncotarget.9229

Maristella Bianconi, Luca Faloppi, Cristian Loretelli, Antonio Zizzi, Riccardo Giampieri, Alessandro Bittoni, Kalliopi Andrikou, Michela Del Prete, Luciano Burattini, Rodolfo Montironi, Mario Scartozzi,  and Stefano Cascinu
37599-37607
Abstract  |  PDF  |  HTML  |  Order a Reprint

Immortalization capacity of HPV types is inversely related to chromosomal instability

Immortalization capacity of HPV types is inversely related to chromosomal instability

https://doi.org/10.18632/oncotarget.8058

Denise M. Schütze, Oscar Krijgsman, Peter J.F. Snijders, Bauke Ylstra, Joachim Weischenfeldt, Balca R. Mardin, Adrian M. Stütz, Jan O. Korbel, Johan P. de Winter, Chris J.L.M. Meijer, Wim G.V. Quint, Leontien Bosch, Saskia M. Wilting,  and Renske D.M. Steenbergen
37608-37621
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis

A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis

https://doi.org/10.18632/oncotarget.9376

Suowen Xu, Bin Liu, Meimei Yin, Marina Koroleva, Michael Mastrangelo, Sara Ture, Craig N. Morrell, David X. Zhang, Edward A. Fisher,  and Zheng Gen Jin
37622-37635
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic landscape of T- and NK-cell post-transplant lymphoproliferative disorders

Genetic landscape of T- and NK-cell post-transplant lymphoproliferative disorders

https://doi.org/10.18632/oncotarget.9400

Elizabeth Margolskee, Vaidehi Jobanputra, Preti Jain, Jinli Chen, Karthik Ganapathi, Odelia Nahum, Brynn Levy, Julie Morscio, Vundavalli Murty, Thomas Tousseyn, Bachir Alobeid, Mahesh Mansukhani,  and Govind Bhagat
37636-37648
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MARCKS contributes to stromal cancer-associated fibroblast activation and facilitates ovarian cancer metastasis

MARCKS contributes to stromal cancer-associated fibroblast activation and facilitates ovarian cancer metastasis

https://doi.org/10.18632/oncotarget.8726

Zongyuan Yang, Sen Xu, Ping Jin, Xin Yang, Xiaoting Li, Dongyi Wan, Taoran Zhang, Sixiang Long, Xiao Wei, Gang Chen, Li Meng, Dan Liu, Yong Fang, Pingbo Chen, Ding Ma,  and Qinglei Gao
37649-37663
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Lysophosphatidic acid stimulates epithelial to mesenchymal transition marker Slug/Snail2 in ovarian cancer cells via Gαi2, Src, and HIF1α signaling nexus

Lysophosphatidic acid stimulates epithelial to mesenchymal transition marker Slug/Snail2 in ovarian cancer cells via Gαi2, Src, and HIF1α signaling nexus

https://doi.org/10.18632/oncotarget.9224

Ji Hee Ha, Jeremy D. Ward, Rangasudhagar Radhakrishnan, Muralidharan Jayaraman, Yong Sang Song,  and Danny N. Dhanasekaran
37664-37679
Abstract  |  PDF  |  HTML  |  Order a Reprint

Phase 1B/2 study of the HSP90 inhibitor AUY922 plus trastuzumab in metastatic HER2-positive breast cancer patients who have progressed on trastuzumab-based regimen

Phase 1B/2 study of the HSP90 inhibitor AUY922 plus trastuzumab in metastatic HER2-positive breast cancer patients who have progressed on trastuzumab-based regimen

https://doi.org/10.18632/oncotarget.8974

Anthony Kong, Daniel Rea, Samreen Ahmed, J. Thaddeus Beck, Rafael López López, Laura Biganzoli, Anne C. Armstrong, Massimo Aglietta, Emilio Alba, Mario Campone, Shu-Fang Hsu Schmitz, Caroline Lefebvre, Mikhail Akimov,  and Soo-Chin Lee
37680-37692
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-mediated epigenetic targeting of Survivin significantly enhances the antitumor activity of paclitaxel against non-small cell lung cancer

MicroRNA-mediated epigenetic targeting of Survivin significantly enhances the antitumor activity of paclitaxel against non-small cell lung cancer

https://doi.org/10.18632/oncotarget.9264

Shuiliang Wang, Ling Zhu, Weimin Zuo, Zhiyong Zeng, Lianghu Huang, Fengjin Lin, Rong Lin, Jin Wang, Jun Lu, Qinghua Wang, Lingjing Lin, Huiyue Dong, Weizhen Wu, Kai Zheng, Jinquan Cai, Shunliang Yang, Yujie Ma, Shixin Ye, Wei Liu, Yinghao Yu, Jianming Tan,  and Bolin Liu
37693-37713
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Blockade of MCP-1/CCR4 signaling-induced recruitment of activated regulatory cells evokes an antitumor immune response in head and neck squamous cell carcinoma

Blockade of MCP-1/CCR4 signaling-induced recruitment of activated regulatory cells evokes an antitumor immune response in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.9265

Wei Sun, Wei-Jin Li, Fan-Qin Wei, Thian-Sze Wong, Wen-Bin Lei, Xiao-Lin Zhu, Jian Li,  and Wei-Ping Wen
37714-37727
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nuclear delivery of recombinant OCT4 by chitosan nanoparticles for transgene-free generation of protein-induced pluripotent stem cells

Nuclear delivery of recombinant OCT4 by chitosan nanoparticles for transgene-free generation of protein-induced pluripotent stem cells

https://doi.org/10.18632/oncotarget.9276

Salma Tammam, Peter Malak, Daphne Correa, Oliver Rothfuss, Hassan M.E. Azzazy, Alf Lamprecht,  and Klaus Schulze-Osthoff
37728-37739
Abstract  |  PDF  |  HTML  |  Order a Reprint

WDR5 high expression and its effect on tumorigenesis in leukemia

WDR5 high expression and its effect on tumorigenesis in leukemia

https://doi.org/10.18632/oncotarget.9312

Zheng Ge, Evelyn J. Song, Yuka Imamura Kawasawa, Jianyong Li, Sinisa Dovat,  and Chunhua Song
37740-37754
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Abdominal scar characteristics as a predictor of cervical stenosis after abdominal radical trachelectomy

Abdominal scar characteristics as a predictor of cervical stenosis after abdominal radical trachelectomy

https://doi.org/10.18632/oncotarget.9318

Xiaoqi Li, Jin Li, Xingzhu Ju, Xiaojun Chen,  and Xiaohua Wu
37755-37761
Abstract  |  PDF  |  HTML  |  Order a Reprint

The IDO1 selective inhibitor epacadostat enhances dendritic cell immunogenicity and lytic ability of tumor antigen-specific T cells

The IDO1 selective inhibitor epacadostat enhances dendritic cell immunogenicity and lytic ability of tumor antigen-specific T cells

https://doi.org/10.18632/oncotarget.9326

Caroline Jochems, Massimo Fantini, Romaine I. Fernando, Anna R. Kwilas, Renee N. Donahue, Lauren M. Lepone, Italia Grenga, Young-Seung Kim, Martin W. Brechbiel, James L. Gulley, Ravi A. Madan, Christopher R. Heery, James W. Hodge, Robert Newton, Jeffrey Schlom,  and Kwong Y. Tsang
37762-37772
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Crosstalk between the HIF-1 and Toll-like receptor/nuclear factor-κB pathways in the oral squamous cell carcinoma microenvironment

Crosstalk between the HIF-1 and Toll-like receptor/nuclear factor-κB pathways in the oral squamous cell carcinoma microenvironment

https://doi.org/10.18632/oncotarget.9329

Shengwei Han, Wenguang Xu, Zhiyong Wang, Xiaofeng Qi, Yufeng Wang, Yanhong Ni, Hao Shen, Qingang Hu,  and Wei Han
37773-37789
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Demonstration of a WNT5A-IL-6 positive feedback loop in melanoma cells: Dual interference of this loop more effectively impairs melanoma cell invasion

Demonstration of a WNT5A-IL-6 positive feedback loop in melanoma cells: Dual interference of this loop more effectively impairs melanoma cell invasion

https://doi.org/10.18632/oncotarget.9332

Rickard Linnskog, Purusottam Mohapatra, Farnaz Moradi, Chandra Prakash Prasad,  and Tommy Andersson
37790-37802
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

dbCPG: A web resource for cancer predisposition genes

dbCPG: A web resource for cancer predisposition genes

https://doi.org/10.18632/oncotarget.9334

Ran Wei, Yao Yao, Wu Yang, Chun-Hou Zheng, Min Zhao,  and Junfeng Xia
37803-37811
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LncRNA-RMRP promotes carcinogenesis by acting as a miR-206 sponge and is used as a novel biomarker for gastric cancer

LncRNA-RMRP promotes carcinogenesis by acting as a miR-206 sponge and is used as a novel biomarker for gastric cancer

https://doi.org/10.18632/oncotarget.9336

Yongfu Shao, Meng Ye, Qier Li, Weiliang Sun, Guoliang Ye, Xinjun Zhang, Yunben Yang, Bingxiu Xiao,  and Junming Guo
37812-37824
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Rs2853677 modulates Snail1 binding to the TERT enhancer and affects lung adenocarcinoma susceptibility

Rs2853677 modulates Snail1 binding to the TERT enhancer and affects lung adenocarcinoma susceptibility

https://doi.org/10.18632/oncotarget.9339

Xiaoting Li, Xing Xu, Jiali Fang, Lin Wang, Yanchao Mu, Peng Zhang, Zhi Yao, Zhenyi Ma,  and Zhe Liu
37825-37838
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circulating AR copy number and outcome to enzalutamide in docetaxel-treated metastatic castration-resistant prostate cancer

Circulating AR copy number and outcome to enzalutamide in docetaxel-treated metastatic castration-resistant prostate cancer

https://doi.org/10.18632/oncotarget.9341

Samanta Salvi, Valentina Casadio, Vincenza Conteduca, Cristian Lolli, Giorgia Gurioli, Filippo Martignano, Giuseppe Schepisi, Sara Testoni, Emanuela Scarpi, Dino Amadori, Daniele Calistri, Gerhardt Attard,  and Ugo De Giorgi
37839-37845
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gene-expression analysis of gleason grade 3 tumor glands embedded in low- and high-risk prostate cancer

Gene-expression analysis of gleason grade 3 tumor glands embedded in low- and high-risk prostate cancer

https://doi.org/10.18632/oncotarget.9344

A. Marije Hoogland, René Böttcher, Esther Verhoef, Guido Jenster,  and Geert J.L.H. van Leenders
37846-37856
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long non-coding RNA Malat1 promotes gallbladder cancer development by acting as a molecular sponge to regulate miR-206

Long non-coding RNA Malat1 promotes gallbladder cancer development by acting as a molecular sponge to regulate miR-206

https://doi.org/10.18632/oncotarget.9347

Shou-Hua Wang, Wen-Jie Zhang, Xiao-Cai Wu, Ming-Di Zhang, Ming-Zhe Weng, Di Zhou, Jian-Dong Wang,  and Zhi-Wei Quan
37857-37867
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long noncoding RNA DANCR promotes invasion of prostate cancer through epigenetically silencing expression of TIMP2/3

Long noncoding RNA DANCR promotes invasion of prostate cancer through epigenetically silencing expression of TIMP2/3

https://doi.org/10.18632/oncotarget.9350

Jing Jia, Feng Li, Xiao-Shuang Tang, Shan Xu, Yang Gao, Qi Shi, Wenhuan Guo, Xinyang Wang, Dalin He,  and Peng Guo
37868-37881
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

DNA demethylating agent decitabine broadens the peripheral T cell receptor repertoire

DNA demethylating agent decitabine broadens the peripheral T cell receptor repertoire

https://doi.org/10.18632/oncotarget.9352

Jing Nie, Yan Zhang, Xiang Li, Meixia Chen, Chuanjie Liu,  and Weidong Han
37882-37892
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Intralesional rose bengal in melanoma elicits tumor immunity via activation of dendritic cells by the release of high mobility group box 1

Intralesional rose bengal in melanoma elicits tumor immunity via activation of dendritic cells by the release of high mobility group box 1

https://doi.org/10.18632/oncotarget.9247

Hao Liu, Pasquale Patrick Innamarato, Krithika Kodumudi, Amy Weber, Satoshi Nemoto, John L. Robinson, Georgina Crago, Timothy McCardle, Erica Royster, Amod A. Sarnaik,  and Shari Pilon-Thomas
37893-37905
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of polycystic ovary syndrome potential drug targets based on pathobiological similarity in the protein-protein interaction network

Identification of polycystic ovary syndrome potential drug targets based on pathobiological similarity in the protein-protein interaction network

https://doi.org/10.18632/oncotarget.9353

Hao Huang, Yuehan He, Wan Li, Wenqing Wei, Yiran Li, Ruiqiang Xie, Shanshan Guo, Yahui Wang, Jing Jiang, Binbin Chen, Junjie Lv, Nana Zhang, Lina Chen,  and Weiming He
37906-37919
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Quantitative assessment of the association between APC promoter methylation and breast cancer

Quantitative assessment of the association between APC promoter methylation and breast cancer

https://doi.org/10.18632/oncotarget.9354

Keli He, Li Zhang,  and Xinghua Long
37920-37930
Abstract  |  PDF  |  HTML  |  Order a Reprint

Granulocytic myeloid-derived suppressor cells promote angiogenesis in the context of multiple myeloma

Granulocytic myeloid-derived suppressor cells promote angiogenesis in the context of multiple myeloma

https://doi.org/10.18632/oncotarget.9270

Marilène Binsfeld, Joséphine Muller, Virginie Lamour, Kim De Veirman, Hendrik De Raeve, Akeila Bellahcène, Els Van Valckenborgh, Frédéric Baron, Yves Beguin, Jo Caers,  and Roy Heusschen
37931-37943
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Piwi-interacting RNAs and PIWI genes as novel prognostic markers for breast cancer

Piwi-interacting RNAs and PIWI genes as novel prognostic markers for breast cancer

https://doi.org/10.18632/oncotarget.9272

Preethi Krishnan, Sunita Ghosh, Kathryn Graham, John R. Mackey, Olga Kovalchuk,  and Sambasivarao Damaraju
37944-37956
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long non-coding RNA metastasis associated in lung adenocarcinoma transcript 1 (MALAT1) interacts with estrogen receptor and predicted poor survival in breast cancer

Long non-coding RNA metastasis associated in lung adenocarcinoma transcript 1 (MALAT1) interacts with estrogen receptor and predicted poor survival in breast cancer

https://doi.org/10.18632/oncotarget.9364

Nai-si Huang, Ya-yun Chi, Jing-yan Xue, Meng-ying Liu, Sheng Huang, Miao Mo, Shu-ling Zhou,  and Jiong Wu
37957-37965
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HDAC5, a potential therapeutic target and prognostic biomarker, promotes proliferation, invasion and migration in human breast cancer

HDAC5, a potential therapeutic target and prognostic biomarker, promotes proliferation, invasion and migration in human breast cancer

https://doi.org/10.18632/oncotarget.9274

Anqi Li, Zebing Liu, Ming Li, Shuling Zhou, Yan Xu, Yaoxing Xiao,  and Wentao Yang
37966-37978
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Bi-directional roles of IRF-1 on autophagy diminish its prognostic value as compared with Ki67 in liver transplantation for hepatocellular carcinoma

Bi-directional roles of IRF-1 on autophagy diminish its prognostic value as compared with Ki67 in liver transplantation for hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9365

Hai-Ming Zhang, Shi-Peng Li, Yao Yu, Zhen Wang, Jin-Dan He, Yan-Jie Xu, Rong-Xin Zhang, Jian-Jun Zhang, Zhi-Jun Zhu,  and Zhong-Yang Shen
37979-37992
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The tumor suppressive miR-200b subfamily is an ERG target gene in human prostate tumors

The tumor suppressive miR-200b subfamily is an ERG target gene in human prostate tumors

https://doi.org/10.18632/oncotarget.9366

Zheng Zhang, Rainer B Lanz, Lijuan Xiao, Lei Wang, Sean M Hartig, Michael M Ittmann, Qin Feng,  and Bin He
37993-38003
Abstract  |  PDF  |  HTML  |  Order a Reprint

GFOD1 and peejar are promising markers for clear-cell renal cell carcinoma disease progression

GFOD1 and peejar are promising markers for clear-cell renal cell carcinoma disease progression

https://doi.org/10.18632/oncotarget.9379

Xiao-rong Wu, Yong-hui Chen, Wei Chen, Wen Kong, Ji-wei Huang, Jin Zhang, Wei Xue, Dong-ming Liu,  and Yi-ran Huang
38004-38009
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CAPE suppresses migration and invasion of prostate cancer cells via activation of non-canonical Wnt signaling

CAPE suppresses migration and invasion of prostate cancer cells via activation of non-canonical Wnt signaling

https://doi.org/10.18632/oncotarget.9380

Jen-Chih Tseng, Ching-Yu Lin, Liang-Chen Su, Hsiao-Hui Fu, Shiaw-Der Yang,  and Chih-Pin Chuu
38010-38024
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Fucoidan inhibits lymphangiogenesis by downregulating the expression of VEGFR3 and PROX1 in human lymphatic endothelial cells

Fucoidan inhibits lymphangiogenesis by downregulating the expression of VEGFR3 and PROX1 in human lymphatic endothelial cells

https://doi.org/10.18632/oncotarget.9443

Yazong Yang, Zixiang Gao, Yanhong Ma, Hongming Teng, Zundong Liu, Hengyun Wei, Yanbing Lu, Xiaofang Cheng, Lin Hou,  and Xiangyang Zou
38025-38035
Abstract  |  PDF  |  HTML  |  Order a Reprint

Notch1 pathway-mediated microRNA-151-5p promotes gastric cancer progression

Notch1 pathway-mediated microRNA-151-5p promotes gastric cancer progression

https://doi.org/10.18632/oncotarget.9342

Kai-Wen Hsu, Wen-Liang Fang, Kuo-Hung Huang, Tzu-Ting Huang, Hsin-Chen Lee, Rong-Hong Hsieh, Chin-Wen Chi,  and Tien-Shun Yeh
38036-38051
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HEY2, a target of miR-137, indicates poor outcomes and promotes cell proliferation and migration in hepatocellular carcinoma

HEY2, a target of miR-137, indicates poor outcomes and promotes cell proliferation and migration in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9343

Dan-Chun Wu, Mei-Fang Zhang, Shu-Guang Su, Heng-Ying Fang, Xue-Hua Wang, Dan He, Yuan-Yuan Xie,  and Xu-Hui Liu
38052-38063
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel p70 S6 kinase-microRNA biogenesis axis mediates multicellular spheroid formation in ovarian cancer progression

A novel p70 S6 kinase-microRNA biogenesis axis mediates multicellular spheroid formation in ovarian cancer progression

https://doi.org/10.18632/oncotarget.9345

Sophia So Ngo Lam, Carman Ka Man Ip, Abby Sin Chi Mak,  and Alice Sze Tsai Wong
38064-38077
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Derivatives of 6-cinnamamido-quinoline-4-carboxamide impair lysosome function and induce apoptosis

Derivatives of 6-cinnamamido-quinoline-4-carboxamide impair lysosome function and induce apoptosis

https://doi.org/10.18632/oncotarget.9348

Hsiao-Hui Kuo, Rajesh Kakadiya, Yi-Chen Wu, Tsann-Long Su, Te-Chang Lee, Yi-Wen Lin,  and Ling-Huei Yih
38078-38090
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Simm530, a novel and highly selective c-Met inhibitor, blocks c-Met-stimulated signaling and neoplastic activities

Simm530, a novel and highly selective c-Met inhibitor, blocks c-Met-stimulated signaling and neoplastic activities

https://doi.org/10.18632/oncotarget.9349

Ying Wang, Zhengsheng Zhan, Xifei Jiang, Xia Peng, Yanyan Shen, Fang Chen, Yinchun Ji, Weiren Liu, Yinghong Shi, Wenhu Duan, Jian Ding, Jing Ai,  and Meiyu Geng
38091-38104
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Phage display library selection of a hypoxia-binding scFv antibody for liver cancer metabolic marker discovery

Phage display library selection of a hypoxia-binding scFv antibody for liver cancer metabolic marker discovery

https://doi.org/10.18632/oncotarget.9460

Jing Liu, Qing Zhang, Hang Chen, Zhihui Gao, Yao Li, Zhongyuan Sun, Rong Xiang,  and Sihe Zhang
38105-38121
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic impact of history of follicular lymphoma, induction regimen and stem cell transplant in patients with MYC/BCL2 double hit lymphoma

Prognostic impact of history of follicular lymphoma, induction regimen and stem cell transplant in patients with MYC/BCL2 double hit lymphoma

https://doi.org/10.18632/oncotarget.9473

Shaoying Li, Annapurna Saksena, Parth Desai, Jie Xu, Zhuang Zuo, Pei Lin, Guilin Tang, C. Cameron Yin, Adam Seegmiller, Jeffrey L. Jorgensen, Roberto N. Miranda, Nishitha M Reddy, Carlos Bueso-Ramos,  and L. Jeffrey Medeiros
38122-38132
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

S100A7 induction is repressed by YAP via the Hippo pathway in A431 cells

S100A7 induction is repressed by YAP via the Hippo pathway in A431 cells

https://doi.org/10.18632/oncotarget.9477

Yunguang Li, Fei Kong, Junhao Wang, Enze Hu, Rui Wang, Jin Liu, Qianqian Xiao, Weiqing Zhang, Dacheng He,  and Xueyuan Xiao
38133-38142
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Down-regulation of tensin2 enhances tumorigenicity and is associated with a variety of cancers

Down-regulation of tensin2 enhances tumorigenicity and is associated with a variety of cancers

https://doi.org/10.18632/oncotarget.9411

Shiao-Ya Hong, Yi-Ping Shih, Peng Sun, Wang-Ju Hsieh, Wen-Chang Lin,  and Su Hao Lo
38143-38153
Abstract  |  PDF  |  HTML  |  Order a Reprint

Down-regulation of ABCG2 and ABCB4 transporters in the placenta of rats exposed to cadmium

Down-regulation of ABCG2 and ABCB4 transporters in the placenta of rats exposed to cadmium

https://doi.org/10.18632/oncotarget.9415

Lili Liu, Liang Zhou, Shuiwang Hu, Shanyu Zhou, Yingyu Deng, Ming Dong, Jianxun Huang, Yuli Zeng, Xiaoyan Chen, Na Zhao, Hongling Li,  and Zhenhua Ding
38154-38163
Abstract  |  PDF  |  HTML  |  Order a Reprint

Quantitation of TGF-β proteins in mouse tissues shows reciprocal changes in TGF-β1 and TGF-β3 in normal vs neoplastic mammary epithelium

Quantitation of TGF-β proteins in mouse tissues shows reciprocal changes in TGF-β1 and TGF-β3 in normal vs neoplastic mammary epithelium

https://doi.org/10.18632/oncotarget.9416

Kathleen C. Flanders, Yu-an Yang, Michelle Herrmann, JinQiu Chen, Nerissa Mendoza, Amer M. Mirza,  and Lalage M. Wakefield
38164-38179
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic heterogeneity in primary and relapsed mantle cell lymphomas: Impact of recurrent CARD11 mutations

Genetic heterogeneity in primary and relapsed mantle cell lymphomas: Impact of recurrent CARD11 mutations

https://doi.org/10.18632/oncotarget.9500

Chenglin Wu, Noel FCC de Miranda, Longyun Chen, Agata M. Wasik, Larry Mansouri, Wojciech Jurczak, Krystyna Galazka, Monika Dlugosz-Danecka, Maciej Machaczka, Huilai Zhang, Roujun Peng, Ryan D. Morin, Richard Rosenquist, Birgitta Sander,  and Qiang Pan-Hammarström
38180-38190
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dual PI3K- and mTOR-inhibitor PI-103 can either enhance or reduce the radiosensitizing effect of the Hsp90 inhibitor NVP-AUY922 in tumor cells: The role of drug-irradiation schedule

Dual PI3K- and mTOR-inhibitor PI-103 can either enhance or reduce the radiosensitizing effect of the Hsp90 inhibitor NVP-AUY922 in tumor cells: The role of drug-irradiation schedule

https://doi.org/10.18632/oncotarget.9501

Cholpon S. Djuzenova, Vanessa Fiedler, Astrid Katzer, Konstanze Michel, Stefanie Deckert, Heiko Zimmermann, Vladimir L. Sukhorukov,  and Michael Flentje
38191-38209
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Efficacy of CD46-targeting chimeric Ad5/35 adenoviral gene therapy for colorectal cancers

Efficacy of CD46-targeting chimeric Ad5/35 adenoviral gene therapy for colorectal cancers

https://doi.org/10.18632/oncotarget.9427

Young-Suk Cho, Manh-Hung Do, Se-Young Kwon, Changjong Moon, Kwonseop Kim, Keesook Lee, Sang-Jin Lee, Silvio Hemmi, Young-Eun Joo, Min Soo Kim,  and Chaeyong Jung
38210-38223
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Significant association between decreased ALDH2 activity and increased sensitivity to genotoxic effects in workers occupationally exposed to styrene

Significant association between decreased ALDH2 activity and increased sensitivity to genotoxic effects in workers occupationally exposed to styrene

https://doi.org/10.18632/oncotarget.9502

Zuquan Weng, Megumi Suda, Mei Wan, Xing Zhang, Dongzhu Guan, Peiqing Zhao, Yuxin Zheng, Muneyuki Miyagawa,  and Rui-Sheng Wang
38224-38234
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Accumulation of RNA-dependent protein kinase (PKR) in the nuclei of lung cancer cells mediates radiation resistance

Accumulation of RNA-dependent protein kinase (PKR) in the nuclei of lung cancer cells mediates radiation resistance

https://doi.org/10.18632/oncotarget.9428

Chuncheng Hao, Ruping Shao, Uma Raju, Bingliang Fang, Stephen G. Swisher,  and Apar Pataer
38235-38242
Abstract  |  PDF  |  HTML  |  Order a Reprint

Drug conjugated nanoparticles activated by cancer cell specific mRNA

Drug conjugated nanoparticles activated by cancer cell specific mRNA

https://doi.org/10.18632/oncotarget.9430

Nathan P. Gossai, Jordan A. Naumann, Nan-Sheng Li, Edward A. Zamora, David J. Gordon, Joseph A. Piccirilli,  and Peter M. Gordon
38243-38256
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Aptamer-guided DNA tetrahedron as a novel targeted drug delivery system for MUC1-expressing breast cancer cells in vitro

Aptamer-guided DNA tetrahedron as a novel targeted drug delivery system for MUC1-expressing breast cancer cells in vitro

https://doi.org/10.18632/oncotarget.9431

Bindong Dai, Yan Hu, JinHong Duan,  and Xian-Da Yang
38257-38269
Abstract  |  PDF  |  HTML  |  Order a Reprint

The BRG1 chromatin remodeling enzyme links cancer cell metabolism and proliferation

The BRG1 chromatin remodeling enzyme links cancer cell metabolism and proliferation

https://doi.org/10.18632/oncotarget.9505

Qiong Wu, Pasil Madany, Jason R. Dobson, Jake M. Schnabl, Soni Sharma, Tara C. Smith, Andre J. van Wijnen, Janet L. Stein, Jane B. Lian, Gary S. Stein, Rohini Muthuswami, Anthony N. Imbalzano,  and Jeffrey A. Nickerson
38270-38281
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Co-option of pre-existing vascular beds in adipose tissue controls tumor growth rates and angiogenesis

Co-option of pre-existing vascular beds in adipose tissue controls tumor growth rates and angiogenesis

https://doi.org/10.18632/oncotarget.9436

Sharon Lim, Kayoko Hosaka, Masaki Nakamura,  and Yihai Cao
38282-38291
Abstract  |  PDF  |  HTML  |  Order a Reprint

Sorafenib inhibits macrophage-mediated epithelial-mesenchymal transition in hepatocellular carcinoma

Sorafenib inhibits macrophage-mediated epithelial-mesenchymal transition in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9438

Yan-Ru Deng, Wen-Bin Liu, Zhe-Xiong Lian, Xingsheng Li,  and Xin Hou
38292-38305
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cabazitaxel operates anti-metastatic and cytotoxic via apoptosis induction and stalls brain tumor angiogenesis

Cabazitaxel operates anti-metastatic and cytotoxic via apoptosis induction and stalls brain tumor angiogenesis

https://doi.org/10.18632/oncotarget.9439

Ali Ghoochani, Gökce Hatipoglu-Majernik, Tina Sehm, Sven Wach, Michael Buchfelder, Helge Taubert, Ilker Y. Eyupoglu,  and Nicolai Savaskan
38306-38318
Abstract  |  PDF  |  HTML  |  Order a Reprint

BET bromodomain-mediated interaction between ERG and BRD4 promotes prostate cancer cell invasion

BET bromodomain-mediated interaction between ERG and BRD4 promotes prostate cancer cell invasion

https://doi.org/10.18632/oncotarget.9513

Alexandra M. Blee, Shujun Liu, Liguo Wang,  and Haojie Huang
38319-38332
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression of EZH2 is associated with the poor prognosis in osteosarcoma and function analysis indicates a therapeutic potential

Overexpression of EZH2 is associated with the poor prognosis in osteosarcoma and function analysis indicates a therapeutic potential

https://doi.org/10.18632/oncotarget.9518

Ranran Sun, Jacson Shen, Yan Gao, Yubing Zhou, Zujiang Yu, Francis Hornicek, Quancheng Kan,  and Zhenfeng Duan
38333-38346
Abstract  |  PDF  |  HTML  |  Order a Reprint

ChREBP promotes the differentiation of leukemia-initiating cells to inhibit leukemogenesis through the TXNIP/RUNX1 pathways

ChREBP promotes the differentiation of leukemia-initiating cells to inhibit leukemogenesis through the TXNIP/RUNX1 pathways

https://doi.org/10.18632/oncotarget.9520

Hongxiang Zeng, Hao Gu, Chiqi Chen, Minle Li, Fangzhen Xia, Li Xie, Xiaoye Liu, Feifei Zhang, Xuemei Tong, Jiangbo Wang, Zhuo Yu,  and Junke Zheng
38347-38358
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Utility of patient-derived lymphoblastoid cell lines as an ex vivo capecitabine sensitivity prediction model for breast cancer patients

Utility of patient-derived lymphoblastoid cell lines as an ex vivo capecitabine sensitivity prediction model for breast cancer patients

https://doi.org/10.18632/oncotarget.9521

Gladys Morrison, Divya Lenkala, Bonnie LaCroix, Dana Ziliak, Vandana Abramson, Phuong Khanh Morrow, Andres Forero, Catherine Van Poznak, Hope S Rugo, Rita Nanda, Peter H. O’Donnell,  and R. Stephanie Huang
38359-38366
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting DNA repair with aphidicolin sensitizes primary chronic lymphocytic leukemia cells to purine analogs

Targeting DNA repair with aphidicolin sensitizes primary chronic lymphocytic leukemia cells to purine analogs

https://doi.org/10.18632/oncotarget.9525

Eliza Starczewska, Maxime Beyaert, Lucienne Michaux, Marie-Christiane Vekemans, Pascale Saussoy, Vanesa Bol, Ainhoa Arana Echarri, Caroline Smal, Eric Van Den Neste,  and Françoise Bontemps
38367-38379
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Radiosensitization by the investigational NEDD8-activating enzyme inhibitor MLN4924 (pevonedistat) in hormone-resistant prostate cancer cells

Radiosensitization by the investigational NEDD8-activating enzyme inhibitor MLN4924 (pevonedistat) in hormone-resistant prostate cancer cells

https://doi.org/10.18632/oncotarget.9526

Xiaofang Wang, Wenjuan Zhang, Zi Yan, Yupei Liang, Lihui Li, Xiaoli Yu, Yan Feng, Shen Fu, Yanmei Zhang, Hu Zhao, Jinha Yu, Lak Shin Jeong, Xiaomao Guo,  and Lijun Jia
38380-38391
Abstract  |  PDF  |  HTML  |  Order a Reprint

Superior mediastinal mature cystic teratoma with gastrointestinal adenocarcinoma transformation: Report of a case

Superior mediastinal mature cystic teratoma with gastrointestinal adenocarcinoma transformation: Report of a case

https://doi.org/10.18632/oncotarget.9532

Chen Lin, Yiqun Du, Yuan Li, Huijie Wang,  and Jianhua Chang
38392-38397
Abstract  |  PDF  |  HTML  |  Order a Reprint

H19 long noncoding RNA alters trophoblast cell migration and invasion by regulating TβR3 in placentae with fetal growth restriction

H19 long noncoding RNA alters trophoblast cell migration and invasion by regulating TβR3 in placentae with fetal growth restriction

https://doi.org/10.18632/oncotarget.9534

Lisa Zuckerwise, Jing Li, Lingeng Lu, Yi Men, Tingting Geng, Catalin S. Buhimschi, Irina A. Buhimschi, Radek Bukowski, Seth Guller, Michael Paidas,  and Yingqun Huang
38398-38407
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression of transmembrane protein 26 (TMEM26) in breast cancer and its association with drug response

Expression of transmembrane protein 26 (TMEM26) in breast cancer and its association with drug response

https://doi.org/10.18632/oncotarget.9493

Norbert Nass, Angela Dittmer, Vicky Hellwig, Theresia Lange, Johanna Mirjam Beyer, Benjamin Leyh, Atanas Ignatov, Christine Weiβenborn, Tove Kirkegaard, Anne E. Lykkesfeldt, Thomas Kalinski,  and Jürgen Dittmer
38408-38426
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Loss of GFAT1 promotes epithelial-to-mesenchymal transition and predicts unfavorable prognosis in gastric cancer

Loss of GFAT1 promotes epithelial-to-mesenchymal transition and predicts unfavorable prognosis in gastric cancer

https://doi.org/10.18632/oncotarget.9538

Fangfang Duan, Dongwei Jia, Junjie Zhao, Weicheng Wu, Lingqiang Min, Shushu Song, Hao Wu, Lan Wang, Hongshan Wang, Yuanyuan Ruan,  and Jianxin Gu
38427-38439
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Validation of a multi-omics strategy for prioritizing personalized candidate driver genes

Validation of a multi-omics strategy for prioritizing personalized candidate driver genes

https://doi.org/10.18632/oncotarget.9540

Li Liang, Liting Song, Yi Yang, Ling Tian, Xiaoyuan Li, Songfeng Wu, Wenxun Huang, Hong Ren, Ni Tang,  and Keyue Ding
38440-38450
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Increased translocation of antigens to endosomes and TLR4 mediated endosomal recruitment of TAP contribute to nicotine augmented cross-presentation

Increased translocation of antigens to endosomes and TLR4 mediated endosomal recruitment of TAP contribute to nicotine augmented cross-presentation

https://doi.org/10.18632/oncotarget.9498

Yan Yan Wang, Chun Fang Hu, Juan Li, Xiang You,  and Feng Guang Gao
38451-38466
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Everolimus affects vasculogenic mimicry in renal carcinoma resistant to sunitinib

Everolimus affects vasculogenic mimicry in renal carcinoma resistant to sunitinib

https://doi.org/10.18632/oncotarget.9542

Maria Serova, Annemilaï Tijeras-Raballand, Celia Dos Santos, Matthieu Martinet, Cindy Neuzillet, Alfred Lopez, Dianne C. Mitchell, Brad A. Bryan, Guillaume Gapihan, Anne Janin, Guilhem Bousquet, Maria Eugenia Riveiro, Ivan Bieche, Sandrine Faivre, Eric Raymond,  and Armand de Gramont
38467-38486
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Transcriptome sequencing identified hub genes for hepatocellular carcinoma by weighted-gene co-expression analysis

Transcriptome sequencing identified hub genes for hepatocellular carcinoma by weighted-gene co-expression analysis

https://doi.org/10.18632/oncotarget.9555

Qi Pan, Xianli Long, Liting Song, Dachun Zhao, Xiaoyuan Li, Dewei Li, Min Li, Jinxue Zhou, Xia Tang, Hong Ren,  and Keyue Ding
38487-38499
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Enhanced anti-tumor activity and cytotoxic effect on cancer stem cell population of metformin-butyrate compared with metformin HCl in breast cancer

Enhanced anti-tumor activity and cytotoxic effect on cancer stem cell population of metformin-butyrate compared with metformin HCl in breast cancer

https://doi.org/10.18632/oncotarget.9522

Kyung-Min Lee, Minju Lee, Jiwoo Lee, Sung Wuk Kim, Hyeong-Gon Moon, Dong-Young Noh,  and Wonshik Han
38500-38512
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dynamic contrast-enhanced MRI coupled with a subtraction technique is useful for treatment response evaluation of malignant melanoma hepatic metastasis

Dynamic contrast-enhanced MRI coupled with a subtraction technique is useful for treatment response evaluation of malignant melanoma hepatic metastasis

https://doi.org/10.18632/oncotarget.9567

Minsu Lee, Song-Ee Baek, Jieun Moon, Yun Ho Roh, Joon Seok Lim, Mi-Suk Park, Myeong-Jin Kim,  and Honsoul Kim
38513-38522
Abstract  |  PDF  |  HTML  |  Order a Reprint

High throughput chemical library screening identifies a novel p110-δ inhibitor that potentiates the anti-myeloma effect of bortezomib

High throughput chemical library screening identifies a novel p110-δ inhibitor that potentiates the anti-myeloma effect of bortezomib

https://doi.org/10.18632/oncotarget.9568

Ehsan Malek,  and James J. Driscoll
38523-38538
Abstract  |  PDF  |  HTML  |  Order a Reprint

Diabetes mellitus stimulates pancreatic cancer growth and epithelial-mesenchymal transition-mediated metastasis via a p38 MAPK pathway

Diabetes mellitus stimulates pancreatic cancer growth and epithelial-mesenchymal transition-mediated metastasis via a p38 MAPK pathway

https://doi.org/10.18632/oncotarget.9533

Lishan Wang, Ying-Ying Bai, Yang Yang, Fangfang Hu, Yonghui Wang, Zeqian Yu, Zhangjun Cheng,  and Jiahua Zhou
38539-38550
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Alterations of androgen receptor-regulated enhancer RNAs (eRNAs) contribute to enzalutamide resistance in castration-resistant prostate cancer

Alterations of androgen receptor-regulated enhancer RNAs (eRNAs) contribute to enzalutamide resistance in castration-resistant prostate cancer

https://doi.org/10.18632/oncotarget.9535

Jingwen Zhao, Yu Zhao, Liguo Wang, Jun Zhang, Jeffrey R. Karnes, Manish Kohli, Guixia Wang,  and Haojie Huang
38551-38565
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Basic fibroblast growth factor promotes VEGF-C-dependent lymphangiogenesis via inhibition of miR-381 in human chondrosarcoma cells

Basic fibroblast growth factor promotes VEGF-C-dependent lymphangiogenesis via inhibition of miR-381 in human chondrosarcoma cells

https://doi.org/10.18632/oncotarget.9570

Huey-En Tzeng, An-Chen Chang, Chun-Hao Tsai, Shih-Wei Wang,  and Chih-Hsin Tang
38566-38578
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association of peripheral leukocyte telomere length and its variation with pancreatic cancer and colorectal cancer risk in Chinese population

Association of peripheral leukocyte telomere length and its variation with pancreatic cancer and colorectal cancer risk in Chinese population

https://doi.org/10.18632/oncotarget.9536

Rui Zhang, Jian Zhao, Jian Xu,  and Fang Liu
38579-38585
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeting Notch-1 positive acute leukemia cells by novel fucose-bound liposomes carrying daunorubicin

Targeting Notch-1 positive acute leukemia cells by novel fucose-bound liposomes carrying daunorubicin

https://doi.org/10.18632/oncotarget.9558

Michihiro Ono, Rishu Takimoto, Takahiro Osuga, Yutaka Okagawa, Masahiro Hirakawa, Makoto Yoshida, Yohei Arihara, Naoki Uemura, Naoki Hayasaka, Shogo Miura, Teppei Matsuno, Fumito Tamura, Yasushi Sato, Tsutomu Sato, Satoshi Iyama, Koji Miyanishi, Kohichi Takada, Masayoshi Kobune,  and Junji Kato
38586-38597
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Selective antitumor activity of roscovitine in head and neck cancer

Selective antitumor activity of roscovitine in head and neck cancer

https://doi.org/10.18632/oncotarget.9560

Cyril Gary, Michael Hajek, Asel Biktasova, Gary Bellinger, Wendell G. Yarbrough,  and Natalia Issaeva
38598-38611
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-320a inhibits breast cancer metastasis by targeting metadherin

MicroRNA-320a inhibits breast cancer metastasis by targeting metadherin

https://doi.org/10.18632/oncotarget.9572

Juan Yu, Ji-Gang Wang, Lei Zhang, Hai-Ping Yang, Lei Wang, Di Ding, Qi Chen, Wen-Lin Yang, Ke-Han Ren, Dan-Mei Zhou, Qiang Zou, Yi-Ting Jin,  and Xiu-Ping Liu
38612-38625
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

JMJD2B is required for Helicobacter pylori-induced gastric carcinogenesis via regulating COX-2 expression

JMJD2B is required for Helicobacter pylori-induced gastric carcinogenesis via regulating COX-2 expression

https://doi.org/10.18632/oncotarget.9573

Fengjuan Han, Juchao Ren, Jinjin Zhang, Yundong Sun, Fang Ma, Zhifang Liu, Han Yu, Jihui Jia,  and Wenjuan Li
38626-38637
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells

Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells

https://doi.org/10.18632/oncotarget.9575

Alessandro Corsaro, Adriana Bajetto, Stefano Thellung, Giulia Begani, Valentina Villa, Mario Nizzari, Alessandra Pattarozzi, Agnese Solari, Monica Gatti, Aldo Pagano, Roberto Würth, Antonio Daga, Federica Barbieri,  and Tullio Florio
38638-38657
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of associations between small molecule drugs and miRNAs based on functional similarity

Identification of associations between small molecule drugs and miRNAs based on functional similarity

https://doi.org/10.18632/oncotarget.9577

Jing Wang, Fanlin Meng, EnYu Dai, Feng Yang, Shuyuan Wang, Xiaowen Chen, Lei Yang, Yuwen Wang,  and Wei Jiang
38658-38669
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Functional/activity network (FAN) analysis of gene-phenotype connectivity liaised by grape polyphenol resveratrol

Functional/activity network (FAN) analysis of gene-phenotype connectivity liaised by grape polyphenol resveratrol

https://doi.org/10.18632/oncotarget.9578

Tze-chen Hsieh, Sheng-Tang Wu, Dylan John Bennett, Barbara B. Doonan, Erxi Wu,  and Joseph M. Wu
38670-38680
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

EAAT3 promotes amino acid transport and proliferation of porcine intestinal epithelial cells

EAAT3 promotes amino acid transport and proliferation of porcine intestinal epithelial cells

https://doi.org/10.18632/oncotarget.9583

Jin-ling Ye, Chun-qi Gao, Xiang-guang Li, Cheng-long Jin, Dan Wang, Gang Shu, Wen-ce Wang, Xiang-feng Kong, Kang Yao, Hui-chao Yan,  and Xiu-qi Wang
38681-38692
Abstract  |  PDF  |  HTML  |  Order a Reprint

Phosphatidylserine-targeted liposome for enhanced glioma-selective imaging

Phosphatidylserine-targeted liposome for enhanced glioma-selective imaging

https://doi.org/10.18632/oncotarget.9584

Liang Zhang, Amyn A. Habib,  and Dawen Zhao
38693-38706
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Exosomal cancer immunotherapy is independent of MHC molecules on exosomes

Exosomal cancer immunotherapy is independent of MHC molecules on exosomes

https://doi.org/10.18632/oncotarget.9585

Stefanie Hiltbrunner, Pia Larssen, Maria Eldh, Maria-Jose Martinez-Bravo, Arnika K. Wagner, Mikael C.I. Karlsson,  and Susanne Gabrielsson
38707-38717
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

BCL-W is a regulator of microtubule inhibitor-induced mitotic cell death

BCL-W is a regulator of microtubule inhibitor-induced mitotic cell death

https://doi.org/10.18632/oncotarget.9586

Shan Huang, Rui Tang,  and Randy Y.C. Poon
38718-38730
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Urinary mRNA biomarker panel for the detection of urothelial carcinoma

Urinary mRNA biomarker panel for the detection of urothelial carcinoma

https://doi.org/10.18632/oncotarget.9587

Virginia Urquidi, Mandy Netherton, Evan Gomes-Giacoia, Daniel Serie, Jeanette Eckel-Passow, Charles J. Rosser,  and Steve Goodison
38731-38740
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Efficient role of IgH 3' regulatory region deficient B-cells in the development of oil granulomas

Efficient role of IgH 3' regulatory region deficient B-cells in the development of oil granulomas

https://doi.org/10.18632/oncotarget.9588

Nour Ghazzaui, Alexis Saintamand, Hussein Issaoui, Faten Saad,  and Yves Denizot
38741-38749
Abstract  |  PDF  |  HTML  |  Order a Reprint

Paf15 expression correlates with rectal cancer prognosis, cell proliferation and radiation response

Paf15 expression correlates with rectal cancer prognosis, cell proliferation and radiation response

https://doi.org/10.18632/oncotarget.9606

Rong Yan, Kun Zhu, Chengxue Dang, Ke Lan, Haonan Wang, Dawei Yuan, Wei Chen, Stephen J. Meltzer,  and Kang Li
38750-38761
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Rare SNPs in receptor tyrosine kinases are negative outcome predictors in multiple myeloma

Rare SNPs in receptor tyrosine kinases are negative outcome predictors in multiple myeloma

https://doi.org/10.18632/oncotarget.9607

Sarah Keppler, Susann Weiβbach, Christian Langer, Stefan Knop, Jordan Pischimarov, Miriam Kull, Thorsten Stühmer, Torsten Steinbrunn, Ralf Bargou, Hermann Einsele, Andreas Rosenwald,  and Ellen Leich
38762-38774
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association of HOTAIR polymorphisms rs4759314 and rs920778 with cancer susceptibility on the basis of ethnicity and cancer type

Association of HOTAIR polymorphisms rs4759314 and rs920778 with cancer susceptibility on the basis of ethnicity and cancer type

https://doi.org/10.18632/oncotarget.9608

Qichao Qi, Jiwei Wang, Bin Huang, Anjing Chen, Gang Li, Xingang Li,  and Jian Wang
38775-38784
Abstract  |  PDF  |  HTML  |  Order a Reprint

Nuclear p16INK4a expression predicts enhanced radiation response in head and neck cancers

Nuclear p16INK4a expression predicts enhanced radiation response in head and neck cancers

https://doi.org/10.18632/oncotarget.9609

Rüveyda Dok, Layka Abbasi Asbagh, Evert Jan Van Limbergen, Anna Sablina,  and Sandra Nuyts
38785-38795
Abstract  |  PDF  |  HTML  |  Order a Reprint

In-depth mapping of the mouse brain N-glycoproteome reveals widespread N-glycosylation of diverse brain proteins

In-depth mapping of the mouse brain N-glycoproteome reveals widespread N-glycosylation of diverse brain proteins

https://doi.org/10.18632/oncotarget.9737

Pan Fang, Xin-jian Wang, Yu Xue, Ming-qi Liu, Wen-feng Zeng, Yang Zhang, Lei Zhang, Xing Gao, Guo-quan Yan, Jun Yao, Hua-li Shen,  and Peng-yuan Yang
38796-38809
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Technetium-99m-labeled rituximab for use as a specific tracer of sentinel lymph node biopsy: a translational research study

Technetium-99m-labeled rituximab for use as a specific tracer of sentinel lymph node biopsy: a translational research study

https://doi.org/10.18632/oncotarget.9614

Xuejuan Wang, Zhi Yang, Baohe Lin, Yan Zhang, Shizhen Zhai, Qichao Zhao, Qing Xie, Fei Liu, Xuedi Han, Jinfeng Li,  and Tao Ouyang
38810-38821
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Downregulation of HSP60 disrupts mitochondrial proteostasis to promote tumorigenesis and progression in clear cell renal cell carcinoma

Downregulation of HSP60 disrupts mitochondrial proteostasis to promote tumorigenesis and progression in clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.9615

Haiping Tang, Yuling Chen, Xiaohui Liu, Shiyu Wang, Yang Lv, Di Wu, Qingtao Wang, Minkui Luo,  and Haiteng Deng
38822-38834
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Radioimmunotherapy of pancreatic cancer xenografts in nude mice using 90Y-labeled anti-α6β4 integrin antibody

Radioimmunotherapy of pancreatic cancer xenografts in nude mice using 90Y-labeled anti-α6β4 integrin antibody

https://doi.org/10.18632/oncotarget.9631

Winn Aung, Atsushi B. Tsuji, Hitomi Sudo, Aya Sugyo, Yoshinori Ukai, Katsushi Kouda, Yoshikazu Kurosawa, Takako Furukawa,  and Tsuneo Saga
38835-38844
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Optimal surgical strategy for hepatocellular carcinoma with portal vein tumor thrombus: A propensity score analysis

Optimal surgical strategy for hepatocellular carcinoma with portal vein tumor thrombus: A propensity score analysis

https://doi.org/10.18632/oncotarget.8642

Yong-Fa Zhang, Yong Le, Wei Wei, Ru-Hai Zou, Jia-Hong Wang, Han-Yue OuYang, Cheng-Zuo Xiao, Xiao-Ping Zhong, Ming Shi,  and Rong-Ping Guo
38845-38856
Abstract  |  PDF  |  HTML  |  Order a Reprint

Alcohol and survival in ESCC: Prediagnosis alcohol consumption and postoperative survival in lymph node-negative esophageal carcinoma patients

Alcohol and survival in ESCC: Prediagnosis alcohol consumption and postoperative survival in lymph node-negative esophageal carcinoma patients

https://doi.org/10.18632/oncotarget.8754

Qilong Ma, Wengao Liu, Ran Jia, Hao Long, Lanjun Zhang, Peng Lin, Hongyun Zhao,  and Guowei Ma
38857-38863
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognosis of subtypes of the mucinous breast carcinoma in Chinese women: a population-based study of 32-year experience (1983-2014)

Prognosis of subtypes of the mucinous breast carcinoma in Chinese women: a population-based study of 32-year experience (1983-2014)

https://doi.org/10.18632/oncotarget.8778

Bo Pan, Ru Yao, Jie Shi, Qian-Qian Xu, Yi-Dong Zhou, Feng Mao, Yan Lin, Jing-Hong Guan, Xue-Jing Wang, Yan-Na Zhang, Xiao-Hui Zhang, Song-Jie Shen, Ying Zhong, Ya-Li Xu, Qing-Li Zhu, Zhi-Yong Liang,  and Qiang Sun
38864-38875
Abstract  |  PDF  |  HTML  |  Order a Reprint

A global assessment of the male predominance in esophageal adenocarcinoma

A global assessment of the male predominance in esophageal adenocarcinoma

https://doi.org/10.18632/oncotarget.9113

Shao-Hua Xie,  and Jesper Lagergren
38876-38883
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A childhood chemotherapy protocol improves overall survival among adults with T-lymphoblastic lymphoma

A childhood chemotherapy protocol improves overall survival among adults with T-lymphoblastic lymphoma

https://doi.org/10.18632/oncotarget.9144

Meng-yuan Zhu, Hua Wang, Chun-yu Huang, Zhong-jun Xia, Xiao-qin Chen, Qi-rong Geng, Wei-da Wang, Liang Wang,  and Yue Lu
38884-38891
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reviews

RAS-MAPK pathway epigenetic activation in cancer: miRNAs in action

RAS-MAPK pathway epigenetic activation in cancer: miRNAs in action

https://doi.org/10.18632/oncotarget.6476

Julien Masliah-Planchon, Simon Garinet,  and Eric Pasmant
38892-38907
Abstract  |  PDF  |  HTML  |  Order a Reprint

The sweet trap in tumors: aerobic glycolysis and potential targets for therapy

The sweet trap in tumors: aerobic glycolysis and potential targets for therapy

https://doi.org/10.18632/oncotarget.7676

Li Yu, Xun Chen, Liantang Wang,  and Shangwu Chen
38908-38926
Abstract  |  PDF  |  HTML  |  Order a Reprint

Extracellular vesicle cross-talk in the bone marrow microenvironment: implications in multiple myeloma

Extracellular vesicle cross-talk in the bone marrow microenvironment: implications in multiple myeloma

https://doi.org/10.18632/oncotarget.7792

Jinheng Wang, Sylvia Faict, Ken Maes, Elke De Bruyne, Els Van Valckenborgh, Rik Schots, Karin Vanderkerken,  and Eline Menu
38927-38945
Abstract  |  PDF  |  HTML  |  Order a Reprint

Perspectives for immunotherapy: which applications might achieve an HIV functional cure?

Perspectives for immunotherapy: which applications might achieve an HIV functional cure?

https://doi.org/10.18632/oncotarget.7793

Vincent Vieillard, Shahin Gharakhanian, Olivier Lucar, Christine Katlama, Odile Launay, Brigitte Autran, Raphael Ho Tsong Fang, Joël Crouzet, Robert L. Murphy,  and Patrice Debré
38946-38958
Abstract  |  PDF  |  HTML  |  Order a Reprint

Current perspectives between metabolic syndrome and cancer

Current perspectives between metabolic syndrome and cancer

https://doi.org/10.18632/oncotarget.8341

Carla Micucci, Debora Valli, Giulia Matacchione,  and Alfonso Catalano
38959-38972
Abstract  |  PDF  |  HTML  |  Order a Reprint

Corrections

Correction: Sunitinib prevents cachexia and prolongs survival of mice bearing renal cancer by restraining STAT3 and MuRF-1 activation in muscle

Correction: Sunitinib prevents cachexia and prolongs survival of mice bearing renal cancer by restraining STAT3 and MuRF-1 activation in muscle

https://doi.org/10.18632/oncotarget.9971

Francesca Pretto, Carmen Ghilardi, Michele Moschetta, Andrea Bassi, Alessandra Rovida, Valentina Scarlato, Laura Talamini, Fabio Fiordaliso, Cinzia Bisighini, Giovanna Damia, Maria Rosa Bani, Rosanna Piccirillo,  and Raffaella Giavazzi
38973
Correction  |  PDF


Copyright © 2017 Impact Journals
Impact Journals is a registered trademark of Impact Journals, LLC