Oncotarget

Vol 7, No 24

June 14, 2016

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Effects of SAL on autophagy in HMLER cells by fluorescence microscopy. See Pellegrini et al.

Table of Contents

Editorial

Natural polymerase fusion as an initiation regulator?

Natural polymerase fusion as an initiation regulator?

https://doi.org/10.18632/oncotarget.9565

Guoliang Lu,  and Peng Gong
35498-35499
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Research Papers: Gerotarget (Focus on Aging)

VPO1 mediates oxidation of LDL and formation of foam cells

VPO1 mediates oxidation of LDL and formation of foam cells

https://doi.org/10.18632/oncotarget.9193

Youfeng Yang, Ruizheng Shi, Zehong Cao, Guogang Zhang,  and Guangjie Cheng
35500-35511
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Age, serum 25-hydroxyvitamin D and vitamin D receptor (VDR) expression and function in peripheral blood mononuclear cells

Age, serum 25-hydroxyvitamin D and vitamin D receptor (VDR) expression and function in peripheral blood mononuclear cells

https://doi.org/10.18632/oncotarget.9398

Laura A. Coleman, Margarita Mishina, Mark Thompson, Sarah M. Spencer, Adrian J. Reber, William G. Davis, Po-Yung Cheng, Edward A. Belongia, H. Keipp Talbot, Maria E. Sundaram, Marie R. Griffin, David K. Shay,  and Suryaprakash Sambhara
35512-35521
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The potential role of epigenetic modulations in BPPV maneuver exercises

The potential role of epigenetic modulations in BPPV maneuver exercises

https://doi.org/10.18632/oncotarget.9446

Kun-Ling Tsai, Chia-To Wang, Chia-Hua Kuo, Yuan-Yang Cheng, Hsin-I Ma, Ching-Hsia Hung, Yi-Ju Tsai,  and Chung-Lan Kao
35522-35534
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Deficiency of myeloid-related proteins 8 and 14 (Mrp8/Mrp14) does not block inflammaging but prevents steatosis

Deficiency of myeloid-related proteins 8 and 14 (Mrp8/Mrp14) does not block inflammaging but prevents steatosis

https://doi.org/10.18632/oncotarget.9550

William R. Swindell, Xianying Xing, Yi Fritz, Doina Diaconu, Daniel I. Simon, Nicole L. Ward,  and Johann E. Gudjonsson
35535-35551
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Sub-acute systemic erythropoietin administration reduces ischemic brain injury in an age-dependent manner

Sub-acute systemic erythropoietin administration reduces ischemic brain injury in an age-dependent manner

https://doi.org/10.18632/oncotarget.9652

Peter Thériault, Audrey Le Béhot, Ayman ElAli,  and Serge Rivest
35552-35561
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Research Papers: Pathology

Aldehyde dehydrogenase 2 inhibits inflammatory response and regulates atherosclerotic plaque

Aldehyde dehydrogenase 2 inhibits inflammatory response and regulates atherosclerotic plaque

https://doi.org/10.18632/oncotarget.9384

Chang Pan, Jun-hui Xing, Cheng Zhang, Ying-mei Zhang, Lue-tao Zhang, Shu-jian Wei, Ming-xiang Zhang, Xu-ping Wang, Qiu-huan Yuan, Li Xue, Jia-li Wang, Zhao-qiang Cui, Yun Zhang, Feng Xu,  and Yu-guo Chen
35562-35576
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impaired macrophage autophagy induces systemic insulin resistance in obesity

Impaired macrophage autophagy induces systemic insulin resistance in obesity

https://doi.org/10.18632/oncotarget.9590

Young-Ho Kang, Mi-Hyang Cho, Ji-Young Kim, Min-Seo Kwon, Jong-Jin Peak, Sang-Wook Kang, Seung-Yong Yoon,  and Youngsup Song
35577-35591
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The molecular mechanism of G2/M cell cycle arrest induced by AFB1 in the jejunum

The molecular mechanism of G2/M cell cycle arrest induced by AFB1 in the jejunum

https://doi.org/10.18632/oncotarget.9594

Heng Yin, Min Jiang, Xi Peng, Hengmin Cui, Yi Zhou, Min He, Zhicai Zuo, Ping Ouyang, Junde Fan,  and Jing Fang
35592-35606
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MiR-499-5p protects cardiomyocytes against ischaemic injury via anti-apoptosis by targeting PDCD4

MiR-499-5p protects cardiomyocytes against ischaemic injury via anti-apoptosis by targeting PDCD4

https://doi.org/10.18632/oncotarget.9597

Yingqing Li, Jianhua Lu, Xueming Bao, Xifu Wang, Junhua Wu, Xiongbin Li,  and Weiqiang Hong
35607-35617
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Poly(ADP-ribose) polymerase 1 inhibition protects cardiomyocytes from inflammation and apoptosis in diabetic cardiomyopathy

Poly(ADP-ribose) polymerase 1 inhibition protects cardiomyocytes from inflammation and apoptosis in diabetic cardiomyopathy

https://doi.org/10.18632/oncotarget.8343

Wei-dong Qin, Guo-liang Liu, Juan Wang, Hao Wang, Jian-ning Zhang, Fan Zhang, Yang Ma, Xin-ying Ji, Chen Li,  and Ming-xiang Zhang
35618-35631
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Risk factor compositions of nonalcoholic fatty liver disease change with body mass index in males and females

Risk factor compositions of nonalcoholic fatty liver disease change with body mass index in males and females

https://doi.org/10.18632/oncotarget.9691

Long Wang, Jinghui Guo,  and Jianping Lu
35632-35642
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Research Papers: Immunology

Inhibition of neddylation regulates dendritic cell functions via Deptor accumulation driven mTOR inactivation

Inhibition of neddylation regulates dendritic cell functions via Deptor accumulation driven mTOR inactivation

https://doi.org/10.18632/oncotarget.9543

Mengmeng Cheng, Shurong Hu, Zhengting Wang, Yaofei Pei, Rong Fan, Xiqiang Liu, Lei Wang, Jie Zhou, Sichang Zheng, Tianyu Zhang, Yun Lin, Maochen Zhang, Ran Tao,  and Jie Zhong
35643-35654
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Using lymph node swelling as a potential biomarker for successful vaccination

Using lymph node swelling as a potential biomarker for successful vaccination

https://doi.org/10.18632/oncotarget.9580

Kimberly D. Brewer, Drew R. DeBay, Iulia Dude, Christa Davis, Kerry Lake, Cathryn Parsons, Rajkannan Rajagopalan, Genevieve Weir, Marianne M. Stanford, Marc Mansour,  and Chris V. Bowen
35655-35669
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Haemonchus contortus excretory and secretory proteins (HcESPs) suppress functions of goat PBMCs in vitro

Haemonchus contortus excretory and secretory proteins (HcESPs) suppress functions of goat PBMCs in vitro

https://doi.org/10.18632/oncotarget.9589

Javaid Ali Gadahi, Bu Yongqian, Muhammad Ehsan, Zhen Chao Zhang, Shuai Wang, Ruo Feng Yan, Xiao Kai Song, Li Xin Xu,  and Xiang Rui Li
35670-35679
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Medicinal herbs Fructus corni and Semen cuscutae suppress allograft rejection via distinct immune mechanisms

Medicinal herbs Fructus corni and Semen cuscutae suppress allograft rejection via distinct immune mechanisms

https://doi.org/10.18632/oncotarget.9680

Xusheng Liu, Yu-Qun Zeng, Yong-Zhuo Liang, Chuan Zou, Huazhen Liu, Feifei Qiu, Chun-Lin Liang, Xiao-Wei Jin, Zi-Ren Su,  and Zhenhua Dai
35680-35691
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Research Papers: Autophagy and Cell Death

Autophagy maintains ubiquitination-proteasomal degradation of Sirt3 to limit oxidative stress in K562 leukemia cells

Autophagy maintains ubiquitination-proteasomal degradation of Sirt3 to limit oxidative stress in K562 leukemia cells

https://doi.org/10.18632/oncotarget.9592

Yixuan Fang, Jian Wang, Li Xu, Yan Cao, Fei Xu, Lili Yan, Meilan Nie, Na Yuan, Suping Zhang, Ruijin Zhao, Hongbin Wang, Mengyin Wu, Xiaoying Zhang,  and Jianrong Wang
35692-35702
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Tumor acidosis enhances cytotoxic effects and autophagy inhibition by salinomycin on cancer cell lines and cancer stem cells

Tumor acidosis enhances cytotoxic effects and autophagy inhibition by salinomycin on cancer cell lines and cancer stem cells

https://doi.org/10.18632/oncotarget.9601

Paola Pellegrini, Matheus Dyczynski, Francesca Vittoria Sbrana, Maria Karlgren, Maria Buoncervello, Maria Hägg-Olofsson, Ran Ma, Johan Hartman, Svetlana Bajalica-Lagercrantz, Dan Grander, Pedram Kharaziha,  and Angelo De Milito
35703-35723
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Research Papers: Chromosome

FBW7 regulates DNA interstrand cross-link repair by modulating FAAP20 degradation

FBW7 regulates DNA interstrand cross-link repair by modulating FAAP20 degradation

https://doi.org/10.18632/oncotarget.9595

Jingming Wang, Ukhyun Jo, So Young Joo,  and Hyungjin Kim
35724-35740
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers

Transtinib, a potent tyrosine kinase inhibitor inhibits L858R/T790M mutant NSCLC cell lines and xenografts

Transtinib, a potent tyrosine kinase inhibitor inhibits L858R/T790M mutant NSCLC cell lines and xenografts

https://doi.org/10.18632/oncotarget.7140

Peng Hu, Da-xiong Han, Run-sheng Ruan, Li-Mou Zheng, Shiu-Huey Chou,  and Chi-Meng Tzeng
35741-35752
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Dual mTORC1/2 inhibition induces anti-proliferative effect in NF1-associated plexiform neurofibroma and malignant peripheral nerve sheath tumor cells

Dual mTORC1/2 inhibition induces anti-proliferative effect in NF1-associated plexiform neurofibroma and malignant peripheral nerve sheath tumor cells

https://doi.org/10.18632/oncotarget.7099

Jennifer Varin, Laury Poulain, Mikael Hivelin, Patrick Nusbaum, Arnaud Hubas, Ingrid Laurendeau, Laurent Lantieri, Pierre Wolkenstein, Michel Vidaud, Eric Pasmant, Nicolas Chapuis,  and Béatrice Parfait
35753-35767
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Quantitative assessment of TIM-3 polymorphisms and cancer risk in Chinese Han population

Quantitative assessment of TIM-3 polymorphisms and cancer risk in Chinese Han population

https://doi.org/10.18632/oncotarget.8157

Xueren Gao, Jiaojiao Yang, Youji He,  and Jianqiong Zhang
35768-35775
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A chemical screen for medulloblastoma identifies quercetin as a putative radiosensitizer

A chemical screen for medulloblastoma identifies quercetin as a putative radiosensitizer

https://doi.org/10.18632/oncotarget.7980

Tonny Lagerweij, Lotte Hiddingh, Dennis Biesmans, Matheus H.W. Crommentuijn, Jacqueline Cloos, Xiao-Nan Li, Mari Kogiso, Bakhos A. Tannous, W. Peter Vandertop, David P. Noske, Gertjan J.L. Kaspers, Tom Würdinger,  and Esther Hulleman
35776-35788
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-320 suppresses colorectal cancer by targeting SOX4, FOXM1, and FOXQ1

MicroRNA-320 suppresses colorectal cancer by targeting SOX4, FOXM1, and FOXQ1

https://doi.org/10.18632/oncotarget.8937

Radhakrishnan Vishnubalaji, Rimi Hamam, Shijun Yue, Omar Al-Obeed, Moustapha Kassem, Fei-Fei Liu, Abdullah Aldahmash,  and Nehad M. Alajez
35789-35802
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The comparison of outcomes from tyrosine kinase inhibitor monotherapy in second- or third-line for advanced non-small-cell lung cancer patients with wild-type or unknown EGFR status

The comparison of outcomes from tyrosine kinase inhibitor monotherapy in second- or third-line for advanced non-small-cell lung cancer patients with wild-type or unknown EGFR status

https://doi.org/10.18632/oncotarget.8130

Giuseppe Bronte, Tindara Franchina, Massimiliano Alù, Giovanni Sortino, Claudia Celesia, Francesco Passiglia, Giuseppina Savio, Agata Laudani, Alessandro Russo, Antonio Picone, Sergio Rizzo, Michele De Tursi, Elisabetta Gambale, Viviana Bazan, Clara Natoli, Livio Blasi, Vincenzo Adamo,  and Antonio Russo
35803-35812
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Strong evidence for LncRNA ZNRD1-AS1, and its functional Cis- eQTL locus contributing more to the susceptibility of lung cancer

Strong evidence for LncRNA ZNRD1-AS1, and its functional Cis- eQTL locus contributing more to the susceptibility of lung cancer

https://doi.org/10.18632/oncotarget.8411

Dan Li, Lei Song, Zhongmei Wen, Xiaoping Li, Jing Jie, Yan Wang,  and Liping Peng
35813-35817
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Copy number variations in urine cell free DNA as biomarkers in advanced prostate cancer

Copy number variations in urine cell free DNA as biomarkers in advanced prostate cancer

https://doi.org/10.18632/oncotarget.9027

Yun Xia, Chiang-Ching Huang, Rachel Dittmar, Meijun Du, Yuan Wang, Hongyan Liu, Niraj Shenoy, Liang Wang,  and Manish Kohli
35818-35831
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Similar cisplatin sensitivity of HPV-positive and -negative HNSCC cell lines

Similar cisplatin sensitivity of HPV-positive and -negative HNSCC cell lines

https://doi.org/10.18632/oncotarget.9028

Chia-Jung Busch, Benjamin Becker, Malte Kriegs, Fruzsina Gatzemeier, Katharina Krüger, Nikolaus Möckelmann, Gerhard Fritz, Cordula Petersen, Rainald Knecht, Kai Rothkamm,  and Thorsten Rieckmann
35832-35842
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Serum amyloid A expression in the breast cancer tissue is associated with poor prognosis

Serum amyloid A expression in the breast cancer tissue is associated with poor prognosis

https://doi.org/10.18632/oncotarget.8561

Mu Yang, Fangfang Liu, Kayoko Higuchi, Jinko Sawashita, Xiaoying Fu, Li Zhang, Lanjing Zhang, Li Fu, Zhongsheng Tong,  and Keiichi Higuchi
35843-35852
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Development and external validation of a prognostic nomogram for gastric cancer using the national cancer registry

Development and external validation of a prognostic nomogram for gastric cancer using the national cancer registry

https://doi.org/10.18632/oncotarget.8221

Jianjun Liu, Qirong Geng, Zhimin Liu, Shangxiang Chen, Jing Guo, Pengfei Kong, YingBo Chen, Wei Li, Zhiwei Zhou, Xiaowei Sun, Youqing Zhan,  and Dazhi Xu
35853-35864
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Determination of radiotherapeutic target zones for thoracic esophageal squamous cell cancer with lower cervical lymph node metastasis according to CT-images

Determination of radiotherapeutic target zones for thoracic esophageal squamous cell cancer with lower cervical lymph node metastasis according to CT-images

https://doi.org/10.18632/oncotarget.9094

Xingde Li, Jin Zhao, Ming Liu, Fushan Zhai, Zhengfei Zhu, Feng Yu, Mingyun Zhang, Lijie Han, Yue Zhao,  and Haiyan Wang
35865-35873
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Polyphenol-rich Avicennia marina leaf extracts induce apoptosis in human breast and liver cancer cells and in a nude mouse xenograft model

Polyphenol-rich Avicennia marina leaf extracts induce apoptosis in human breast and liver cancer cells and in a nude mouse xenograft model

https://doi.org/10.18632/oncotarget.8624

Cheng Huang, Chung-Kuang Lu, Ming-Chin Tu, Jia-Hua Chang, Yen-Ju Chen, Yu-Hsuan Tu,  and Hsiu-Chen Huang
35874-35893
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Effective elimination of liver cancer stem-like cells by CD90 antibody targeted thermosensitive magnetoliposomes

Effective elimination of liver cancer stem-like cells by CD90 antibody targeted thermosensitive magnetoliposomes

https://doi.org/10.18632/oncotarget.9116

Rui Yang, Li Y. An, Qin F. Miao, Feng M. Li, Yong Han, Hui X. Wang, Dang P. Liu, Rong Chen,  and Sha Q. Tang
35894-35916
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Transforming growth factor-β promotes aggressiveness and invasion of clear cell renal cell carcinoma

Transforming growth factor-β promotes aggressiveness and invasion of clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.9177

Raviprakash T. Sitaram, Pramod Mallikarjuna, Maréne Landström,  and Börje Ljungberg
35917-35931
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer

The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer

https://doi.org/10.18632/oncotarget.8321

Jean-Philippe Foy, Antonin Tortereau, Carlos Caulin, Vincent Le Texier, Emilie Lavergne, Emilie Thomas, Sylvie Chabaud, David Perol, Joël Lachuer, Wenhua Lang, Waun Ki Hong, Patrick Goudot, Scott M. Lippman, Chloé Bertolus,  and Pierre Saintigny
35932-35945
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The histone methyltransferase EZH2 as a novel prosurvival factor in clinically aggressive chronic lymphocytic leukemia

The histone methyltransferase EZH2 as a novel prosurvival factor in clinically aggressive chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.9371

Nikos Papakonstantinou, Stavroula Ntoufa, Elisavet Chartomatsidou, Konstantia Kotta, Andreas Agathangelidis, Lefki Giassafaki, Tzeni Karamanli, Panagiota Bele, Theodoros Moysiadis, Panagiotis Baliakas, Lesley Ann Sutton, Niki Stavroyianni, Achilles Anagnostopoulos, Antonios M. Makris, Paolo Ghia, Richard Rosenquist,  and Kostas Stamatopoulos
35946-35959
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hsa-miR-134 suppresses non-small cell lung cancer (NSCLC) development through down-regulation of CCND1

Hsa-miR-134 suppresses non-small cell lung cancer (NSCLC) development through down-regulation of CCND1

https://doi.org/10.18632/oncotarget.8482

Cheng-Cao Sun, Shu-Jun Li,  and De-Jia Li
35960-35978
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical and genetic features of lung squamous cell cancer in never-smokers

Clinical and genetic features of lung squamous cell cancer in never-smokers

https://doi.org/10.18632/oncotarget.8745

Yangle Huang, Rui Wang, Yunjian Pan, Yang Zhang, Hang Li, Chao Cheng, Difan Zheng, Shanbo Zheng, Yuan Li, Xuxia Shen, Haichuan Hu, Deng Cai, Shengfei Wang, Yawei Zhang, Jiaqing Xiang, Yihua Sun, Jie Zhang,  and Haiquan Chen
35979-35988
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of myeloproliferative neoplasm drug agents via predictive simulation modeling: assessing responsiveness with micro-environment derived cytokines

Identification of myeloproliferative neoplasm drug agents via predictive simulation modeling: assessing responsiveness with micro-environment derived cytokines

https://doi.org/10.18632/oncotarget.8540

Susumu S. Kobayashi, Shireen Vali, Ansu Kumar, Neeraj Singh, Taher Abbasi,  and Peter P. Sayeski
35989-36001
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dendrimer antibody conjugate to target and image HER-2 overexpressing cancer cells

Dendrimer antibody conjugate to target and image HER-2 overexpressing cancer cells

https://doi.org/10.18632/oncotarget.9081

James B. Otis, Hong Zong, Alina Kotylar, Anna Yin, Somnath Bhattacharjee, Han Wang, James R. Baker Jr,  and Su He Wang
36002-36013
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

NME8 rs2718058 polymorphism with Alzheimer’s disease risk: a replication and meta-analysis

NME8 rs2718058 polymorphism with Alzheimer’s disease risk: a replication and meta-analysis

https://doi.org/10.18632/oncotarget.9086

Shu-Lei Liu, Xue-Chun Wang, Meng-Shan Tan, Hui-Fu Wang, Wei Zhang, Zi-Xuan Wang, Jin-Tai Yu,  and Lan Tan
36014-36020
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Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema

Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema

https://doi.org/10.18632/oncotarget.8651

Tina Sehm, Zheng Fan, Ali Ghoochani, Manfred Rauh, Tobias Engelhorn, Georgia Minakaki, Arnd Dörfler, Jochen Klucken, Michael Buchfelder, Ilker Y. Eyüpoglu,  and Nicolai Savaskan
36021-36033
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Cytoplasmic calcium increase via fusion with inactivated Sendai virus induces apoptosis in human multiple myeloma cells by downregulation of c-Myc oncogene

Cytoplasmic calcium increase via fusion with inactivated Sendai virus induces apoptosis in human multiple myeloma cells by downregulation of c-Myc oncogene

https://doi.org/10.18632/oncotarget.9105

Yingzhe Jiang, Kotaro Saga, Yasuhide Miyamoto,  and Yasufumi Kaneda
36034-36048
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oncogenic function of the homeobox A13-long noncoding RNA HOTTIP-insulin growth factor-binding protein 3 axis in human gastric cancer

Oncogenic function of the homeobox A13-long noncoding RNA HOTTIP-insulin growth factor-binding protein 3 axis in human gastric cancer

https://doi.org/10.18632/oncotarget.9102

Sophie S.W. Wang, Kenly Wuputra, Chung-Jung Liu, Yin-Chu Lin, Yi-Ting Chen, Chee-Yin Chai, Chen-Lung Steve Lin, Kung-Kai Kuo, Ming-Ho Tsai, Shin-Wei Wang, Ker-Kong Chen, Hiroyuki Miyoshi, Yukio Nakamura, Shigeo Saito, Tadashi Hanafusa, Deng-Chyang Wu, Chang-Shen Lin,  and Kazunari K. Yokoyama
36049-36064
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinicopathological and prognostic significance of regulatory T cells in patients with non-small cell lung cancer: A systematic review with meta-analysis

Clinicopathological and prognostic significance of regulatory T cells in patients with non-small cell lung cancer: A systematic review with meta-analysis

https://doi.org/10.18632/oncotarget.9130

Sha Zhao, Tao Jiang, Limin Zhang, Hui Yang, Xiaozhen Liu, Yijun Jia,  and Caicun Zhou
36065-36073
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Defective STAT1 activation associated with impaired IFN-γ production in NK and T lymphocytes from metastatic melanoma patients treated with IL-2

Defective STAT1 activation associated with impaired IFN-γ production in NK and T lymphocytes from metastatic melanoma patients treated with IL-2

https://doi.org/10.18632/oncotarget.8683

Geok Choo Sim, Sheng Wu, Lei Jin, Patrick Hwu,  and Laszlo G. Radvanyi
36074-36091
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of breast cancer candidate genes using gene co-expression and protein-protein interaction information

Identification of breast cancer candidate genes using gene co-expression and protein-protein interaction information

https://doi.org/10.18632/oncotarget.9132

Zhenyu Yue, Hai-Tao Li, Yabing Yang, Sajid Hussain, Chun-Hou Zheng, Junfeng Xia,  and Yan Chen
36092-36100
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Identification of a novel partner gene, KIAA1217, fused to RET: Functional characterization and inhibitor sensitivity of two isoforms in lung adenocarcinoma

Identification of a novel partner gene, KIAA1217, fused to RET: Functional characterization and inhibitor sensitivity of two isoforms in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.9137

Mi-Sook Lee, Ryong Nam Kim, Hoseok I, Doo-Yi Oh, Ji-Young Song, Ka-Won Noh, Yu-Jin Kim, Jung Wook Yang, Maruja E. Lira, Chang Hun Lee, Min Ki Lee, Yeoung Dae Kim, Mao Mao, Joungho Han, Jhingook Kim,  and Yoon-La Choi
36101-36114
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

EZH2-mediated repression of GSK-3β and TP53 promotes Wnt/β-catenin signaling-dependent cell expansion in cervical carcinoma

EZH2-mediated repression of GSK-3β and TP53 promotes Wnt/β-catenin signaling-dependent cell expansion in cervical carcinoma

https://doi.org/10.18632/oncotarget.8741

Qian Chen, Peng-Sheng Zheng,  and Wen-Ting Yang
36115-36129
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Which melanoma patient carries a BRAF-mutation? A comparison of predictive models

Which melanoma patient carries a BRAF-mutation? A comparison of predictive models

https://doi.org/10.18632/oncotarget.9143

Thomas Eigentler, Zeinab Assi, Jessica C. Hassel, Lucie Heinzerling, Hans Starz, Mark Berneburg, Jürgen Bauer,  and Claus Garbe
36130-36137
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Functional oncogene signatures guide rationally designed combination therapies to synergistically induce breast cancer cell death

Functional oncogene signatures guide rationally designed combination therapies to synergistically induce breast cancer cell death

https://doi.org/10.18632/oncotarget.9147

Stephen T. Guest, Zachary R. Kratche, Jonathan C. Irish, Robert C. Wilson, Ramsi Haddad, Joe W. Gray, Elizabeth Garrett-Mayer,  and Stephen P. Ethier
36138-36153
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Novel 1, 3-N, O-Spiroheterocyclic compounds inhibit heparanase activity and enhance nedaplatin-induced cytotoxicity in cervical cancer cells

Novel 1, 3-N, O-Spiroheterocyclic compounds inhibit heparanase activity and enhance nedaplatin-induced cytotoxicity in cervical cancer cells

https://doi.org/10.18632/oncotarget.8959

Yanan Song, Bin Hu, Hongjie Qu, Lu Wang, Yunxiao Zhang, Jinchao Tao,  and Jinquan Cui
36154-36167
Abstract  |  PDF  |  HTML  |  Order a Reprint

SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline

SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline

https://doi.org/10.18632/oncotarget.8786

Maxime Guéguinou, Thomas Harnois, David Crottes, Arnaud Uguen, Nadine Deliot, Audrey Gambade, Aurélie Chantôme, Jean Pierre Haelters, Paul Alain Jaffrès, Marie Lise Jourdan, Günther Weber, Olivier Soriani, Philippe Bougnoux, Olivier Mignen, Nicolas Bourmeyster, Bruno Constantin, Thierry Lecomte, Christophe Vandier,  and Marie Potier-Cartereau
36168-36184
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Loss of AIM2 expression promotes hepatocarcinoma progression through activation of mTOR-S6K1 pathway

Loss of AIM2 expression promotes hepatocarcinoma progression through activation of mTOR-S6K1 pathway

https://doi.org/10.18632/oncotarget.9154

Xiaomin Ma, Pengbo Guo, Yumin Qiu, Kun Mu, Lihui Zhu, Wei Zhao, Tao Li,  and Lihui Han
36185-36197
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical significance of the preoperative platelet count and platelet-to-lymphocyte ratio (PLT-PLR) in patients with surgically resected non-small cell lung cancer

Clinical significance of the preoperative platelet count and platelet-to-lymphocyte ratio (PLT-PLR) in patients with surgically resected non-small cell lung cancer

https://doi.org/10.18632/oncotarget.8809

Seok-Hyun Kim, Hyoun Wook Lee, Se-Il Go, Soon Il Lee,  and Gyeong-Won Lee
36198-36206
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Reduced miR-200b and miR-200c expression contributes to abnormal hepatic lipid accumulation by stimulating JUN expression and activating the transcription of srebp1

Reduced miR-200b and miR-200c expression contributes to abnormal hepatic lipid accumulation by stimulating JUN expression and activating the transcription of srebp1

https://doi.org/10.18632/oncotarget.9183

Jun Guo, Weiwei Fang, Libo Sun, Yonggang Lu, Lin Dou, Xiuqing Huang, Mingxiao Sun, Cheng Pang, Jing Qu, Guanghui Liu,  and Jian Li
36207-36219
Abstract  |  PDF  |  HTML  |  Order a Reprint

A miR-200c/141-BMI1 autoregulatory loop regulates oncogenic activity of BMI1 in cancer cells

A miR-200c/141-BMI1 autoregulatory loop regulates oncogenic activity of BMI1 in cancer cells

https://doi.org/10.18632/oncotarget.8811

Manjari Dimri, Mingu Kang,  and Goberdhan P. Dimri
36220-36234
Abstract  |  PDF  |  HTML  |  Order a Reprint

Co-inhibition of EGFR and IGF1R synergistically impacts therapeutically on adrenocortical carcinoma

Co-inhibition of EGFR and IGF1R synergistically impacts therapeutically on adrenocortical carcinoma

https://doi.org/10.18632/oncotarget.8827

Lieyu Xu, Yicheng Qi, Yunze Xu, Jianpo Lian, Xiaojing Wang, Guang Ning, Weiqing Wang,  and Yu Zhu
36235-36246
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-133b inhibits glioma cell proliferation and invasion by targeting Sirt1

miR-133b inhibits glioma cell proliferation and invasion by targeting Sirt1

https://doi.org/10.18632/oncotarget.9198

Chuntao Li, Zhixiong Liu, Kui Yang, Xin Chen, Yu Zeng, Jinfang Liu, Zhenyan Li,  and Yunsheng Liu
36247-36254
Abstract  |  PDF  |  HTML  |  Order a Reprint

The Hippo transducer TAZ promotes cell proliferation and tumor formation of glioblastoma cells through EGFR pathway

The Hippo transducer TAZ promotes cell proliferation and tumor formation of glioblastoma cells through EGFR pathway

https://doi.org/10.18632/oncotarget.9199

Rui Yang, Yanan Wu, Jiahua Zou, Ji Zhou, Mei Wang, Xiangwei Hao,  and Hongjuan Cui
36255-36265
Abstract  |  PDF  |  HTML  |  Order a Reprint

TP53 mutation variant allele frequency is a potential predictor for clinical outcome of patients with lower-risk myelodysplastic syndromes

TP53 mutation variant allele frequency is a potential predictor for clinical outcome of patients with lower-risk myelodysplastic syndromes

https://doi.org/10.18632/oncotarget.9200

Monika Belickova, Jitka Vesela, Anna Jonasova, Barbora Pejsova, Hana Votavova, Michaela Dostalova Merkerova, Zuzana Zemanova, Jana Brezinova, Dana Mikulenkova, Marie Lauermannova, Jan Valka, Kyra Michalova, Radana Neuwirtova,  and Jaroslav Cermak
36266-36279
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

In vitro functional characterization of prostaglandin-endoperoxide synthase 2 during chondrocyte hypertrophic differentiation

In vitro functional characterization of prostaglandin-endoperoxide synthase 2 during chondrocyte hypertrophic differentiation

https://doi.org/10.18632/oncotarget.8889

Na Li, Qian Wang, Ting Zhu, Longwei Qiao, Fei Zhang, Rui Mi, Bo Wang, Lin Chen, Junxia Gu, Yaojuan Lu,  and Qiping Zheng
36280-36292
Abstract  |  PDF  |  HTML  |  Order a Reprint

Unveiling MYCN regulatory networks in neuroblastoma via integrative analysis of heterogeneous genomics data

Unveiling MYCN regulatory networks in neuroblastoma via integrative analysis of heterogeneous genomics data

https://doi.org/10.18632/oncotarget.9202

Chia-Lang Hsu, Hsin-Yi Chang, Jen-Yun Chang, Wen-Ming Hsu, Hsuan-Cheng Huang,  and Hsueh-Fen Juan
36293-36310
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeted sequencing identifies genetic alterations that confer primary resistance to EGFR tyrosine kinase inhibitor (Korean Lung Cancer Consortium)

Targeted sequencing identifies genetic alterations that confer primary resistance to EGFR tyrosine kinase inhibitor (Korean Lung Cancer Consortium)

https://doi.org/10.18632/oncotarget.8904

Sun Min Lim, Hye Ryun Kim, Eun Kyung Cho, Young Joo Min, Jin Seok Ahn, Myung-Ju Ahn, Keunchil Park, Byoung Chul Cho, Ji-Hyun Lee, Hye Cheol Jeong, Eun Kyung Kim,  and Joo-Hang Kim
36311-36320
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting miR-21-3p inhibits proliferation and invasion of ovarian cancer cells

Targeting miR-21-3p inhibits proliferation and invasion of ovarian cancer cells

https://doi.org/10.18632/oncotarget.9216

Perla M. Báez-Vega, Ileabett M. Echevarría Vargas, Fatma Valiyeva, Joel Encarnación-Rosado, Adriana Roman, Josean Flores, María J. Marcos-Martínez,  and Pablo E. Vivas-Mejía
36321-36337
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-126 induces autophagy by altering cell metabolism in malignant mesothelioma

MicroRNA-126 induces autophagy by altering cell metabolism in malignant mesothelioma

https://doi.org/10.18632/oncotarget.8916

Marco Tomasetti, Federica Monaco, Nicola Manzella, Jakub Rohlena, Katerina Rohlenova, Sara Staffolani, Simona Gaetani, Veronica Ciarapica, Monica Amati, Massimo Bracci, Matteo Valentino, Jacob Goodwin, Maria Nguyen, Jaroslav Truksa, Margaryta Sobol, Pavel Hozak, Lan-Feng Dong, Lory Santarelli,  and Jiri Neuzil
36338-36352
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

DNA damaging agent-induced apoptosis is regulated by MCL-1 phosphorylation and degradation mediated by the Noxa/MCL-1/CDK2 complex

DNA damaging agent-induced apoptosis is regulated by MCL-1 phosphorylation and degradation mediated by the Noxa/MCL-1/CDK2 complex

https://doi.org/10.18632/oncotarget.9217

Wataru Nakajima, Kanika Sharma, June Young Lee, Nicolas T. Maxim, Mark A. Hicks, Thien-Trang Vu, Angela Luu, W. Andrew Yeudall, Nobuyuki Tanaka,  and Hisashi Harada
36353-36365
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Altered expression pattern of circular RNAs in primary and metastatic sites of epithelial ovarian carcinoma

Altered expression pattern of circular RNAs in primary and metastatic sites of epithelial ovarian carcinoma

https://doi.org/10.18632/oncotarget.8917

Ikhlak Ahmed, Thasni Karedath, Simeon S. Andrews, Iman K. Al-Azwani, Yasmin Ali Mohamoud, Denis Querleu, Arash Rafii,  and Joel A. Malek
36366-36381
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Liposomal bortezomib is active against chronic myeloid leukemia by disrupting the Sp1-BCR/ABL axis

Liposomal bortezomib is active against chronic myeloid leukemia by disrupting the Sp1-BCR/ABL axis

https://doi.org/10.18632/oncotarget.8871

Xiaojuan Yang, Jiuxia Pang, Na Shen, Fei Yan, Lai-Chu Wu, Aref Al-Kali, Mark R. Litzow, Yong Peng, Robert J. Lee,  and Shujun Liu
36382-36394
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ER stress inducer tunicamycin suppresses the self-renewal of glioma-initiating cell partly through inhibiting Sox2 translation

ER stress inducer tunicamycin suppresses the self-renewal of glioma-initiating cell partly through inhibiting Sox2 translation

https://doi.org/10.18632/oncotarget.8954

Yang Xing, Yuqing Ge, Chanjuan Liu, Xiaobiao Zhang, Jianhai Jiang,  and Yuanyan Wei
36395-36406
Abstract  |  PDF  |  HTML  |  Order a Reprint

AJUBA promotes the migration and invasion of esophageal squamous cell carcinoma cells through upregulation of MMP10 and MMP13 expression

AJUBA promotes the migration and invasion of esophageal squamous cell carcinoma cells through upregulation of MMP10 and MMP13 expression

https://doi.org/10.18632/oncotarget.9239

Xuejiao Shi, Zhaoli Chen, Xueda Hu, Mei Luo, Zengmiao Sun, Jiagen Li, Susheng Shi, Xiaoli Feng, Chengcheng Zhou, Zitong Li, Wenhui Yang, Yuan Li, Pan Wang, Fang Zhou, Yibo Gao,  and Jie He
36407-36418
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Functional cooperation between KCa3.1 and TRPC1 channels in human breast cancer: Role in cell proliferation and patient prognosis

Functional cooperation between KCa3.1 and TRPC1 channels in human breast cancer: Role in cell proliferation and patient prognosis

https://doi.org/10.18632/oncotarget.9261

Malika Faouzi, Frederic Hague, Dirk Geerts, Anne-Sophie Ay, Marie Potier-Cartereau, Ahmed Ahidouch,  and Halima Ouadid-Ahidouch
36419-36435
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Selection and characterization of DNA aptamer for metastatic prostate cancer recognition and tissue imaging

Selection and characterization of DNA aptamer for metastatic prostate cancer recognition and tissue imaging

https://doi.org/10.18632/oncotarget.9262

Minlan Duan, Yuqian Long, Cai Yang, Xiaoqiu Wu, Yang Sun, Jianglin Li, Xiaoxiao Hu, Wei Lin, Dongmei Han, Yifan Zhao, Jing Liu, Mao Ye,  and Weihong Tan
36436-36446
Abstract  |  PDF  |  HTML  |  Order a Reprint

The role of VDR and BIM in potentiation of cytarabine–induced cell death in human AML blasts

The role of VDR and BIM in potentiation of cytarabine–induced cell death in human AML blasts

https://doi.org/10.18632/oncotarget.8998

Xuening Wang,  and George P. Studzinski
36447-36460
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combining 2-deoxy-D-glucose with fenofibrate leads to tumor cell death mediated by simultaneous induction of energy and ER stress

Combining 2-deoxy-D-glucose with fenofibrate leads to tumor cell death mediated by simultaneous induction of energy and ER stress

https://doi.org/10.18632/oncotarget.9263

Huaping Liu, Metin Kurtoglu, Clara Lucia León-Annicchiarico, Cristina Munoz-Pinedo, Julio Barredo, Guy Leclerc, Jaime Merchan, Xiongfei Liu,  and Theodore J. Lampidis
36461-36473
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Relative telomere lengths in tumor and normal mucosa are related to disease progression and chromosome instability profiles in colorectal cancer

Relative telomere lengths in tumor and normal mucosa are related to disease progression and chromosome instability profiles in colorectal cancer

https://doi.org/10.18632/oncotarget.9015

Nirosha Suraweera, Dmitri Mouradov, Shan Li, Robert N. Jorissen, Debbie Hampson, Anil Ghosh, Neel Sengupta, Mohamed Thaha, Shafi Ahmed, Michael Kirwan, Floor Aleva, David Propper, Roger M. Feakins, Tom Vulliamy, Ngaire J. Elwood, Pei Tian, Robyn L. Ward, Nicholas J. Hawkins, Zheng-Zhou Xu, Peter L. Molloy, Ian T. Jones, Matthew Croxford, Peter Gibbs, Andrew Silver,  and Oliver M. Sieber
36474-36488
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ISL1, a novel regulator of CCNB1, CCNB2 and c-MYC genes, promotes gastric cancer cell proliferation and tumor growth

ISL1, a novel regulator of CCNB1, CCNB2 and c-MYC genes, promotes gastric cancer cell proliferation and tumor growth

https://doi.org/10.18632/oncotarget.9269

Qiong Shi, Weiping Wang, Zhuqing Jia, Ping Chen, Kangtao Ma,  and Chunyan Zhou
36489-36500
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

BRG1 targeting STAT3/VEGFC signaling regulates lymphangiogenesis in colorectal cancer

BRG1 targeting STAT3/VEGFC signaling regulates lymphangiogenesis in colorectal cancer

https://doi.org/10.18632/oncotarget.9038

Xu Zhu, Li Sun, Jingqin Lan, Linli Xu, Meng Zhang, Xuelai Luo, Jianping Gong, Guihua Wang, Xianglin Yuan, Junbo Hu,  and Jing Wang
36501-36509
Abstract  |  PDF  |  HTML  |  Order a Reprint

CDK5 promotes renal tubulointerstitial fibrosis in diabetic nephropathy via ERK1/2/PPARγ pathway

CDK5 promotes renal tubulointerstitial fibrosis in diabetic nephropathy via ERK1/2/PPARγ pathway

https://doi.org/10.18632/oncotarget.9058

Xiaoyan Bai, Xiaoyan Hou, Jianwei Tian, Jian Geng,  and Xiao Li
36510-36528
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-300 inhibited glioblastoma progression through ROCK1

MicroRNA-300 inhibited glioblastoma progression through ROCK1

https://doi.org/10.18632/oncotarget.9068

Fucheng Zhou, Yang Li, Zhen Hao, Xuanxi Liu, Liang Chen, Yu Cao, Zuobin Liang, Fei Yuan, Jie Liu, Jianjiao Wang, Yongri Zheng, Deli Dong, Shan Bian, Baofeng Yang, Chuanlu Jiang,  and Qingsong Li
36529-36538
Abstract  |  PDF  |  HTML  |  Order a Reprint

p70S6K promotes IL-6-induced epithelial-mesenchymal transition and metastasis of head and neck squamous cell carcinoma

p70S6K promotes IL-6-induced epithelial-mesenchymal transition and metastasis of head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.9282

Dandan Wu, Jie Cheng, Geng Sun, Shengjie Wu, Min Li, Zhongyuan Gao, Sulan Zhai, Ping Li, Dongming Su,  and Xuerong Wang
36539-36550
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Zinc finger protein 91 (ZFP91) activates HIF-1α via NF-κB/p65 to promote proliferation and tumorigenesis of colon cancer

Zinc finger protein 91 (ZFP91) activates HIF-1α via NF-κB/p65 to promote proliferation and tumorigenesis of colon cancer

https://doi.org/10.18632/oncotarget.9070

Juan Ma, Chunliu Mi, Ke Si Wang, Jung Joon Lee,  and Xuejun Jin
36551-36562
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sulfatide interacts with and activates integrin αVβ3 in human hepatocellular carcinoma cells

Sulfatide interacts with and activates integrin αVβ3 in human hepatocellular carcinoma cells

https://doi.org/10.18632/oncotarget.9095

Rong Wang, Bing Qi, Yi Wei Dong, Qian Qian Cai, Nian Hui Deng, Qi Chen, Chao Li, Yu Tong Jin,  and Xing Zhong Wu
36563-36576
Abstract  |  PDF  |  HTML  |  Order a Reprint

Downregulated miR-31 level associates with poor prognosis of gastric cancer and its restoration suppresses tumor cell malignant phenotypes by inhibiting E2F2

Downregulated miR-31 level associates with poor prognosis of gastric cancer and its restoration suppresses tumor cell malignant phenotypes by inhibiting E2F2

https://doi.org/10.18632/oncotarget.9288

Huaidong Wang, Xiaotian Zhang, Yuxin Liu, Zhaohui Ni, Yan Lin, Zipeng Duan, Yue Shi, Guoqing Wang,  and Fan Li
36577-36589
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic alteration profiling of patients with resected squamous cell lung carcinomas

Genetic alteration profiling of patients with resected squamous cell lung carcinomas

https://doi.org/10.18632/oncotarget.9096

Dan Tao, Xiaohong Han, Ningning Zhang, Dongmei Lin, Di Wu, Xinxin Zhu, Wenya Song,  and Yuankai Shi
36590-36601
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeted photo-chemo therapy of malignancy on the chest wall while cardiopulmonary avoidance based on Fe3O4@ZnO nanocomposites

Targeted photo-chemo therapy of malignancy on the chest wall while cardiopulmonary avoidance based on Fe3O4@ZnO nanocomposites

https://doi.org/10.18632/oncotarget.9123

Haijun Zhang, Liting Guo, Shuang Ding, Jian Xiong,  and Baoan Chen
36602-36613
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-126-3p suppresses cell proliferation by targeting PIK3R2 in Kaposi’s sarcoma cells

MicroRNA-126-3p suppresses cell proliferation by targeting PIK3R2 in Kaposi’s sarcoma cells

https://doi.org/10.18632/oncotarget.9311

Xiu-Juan Wu, Zong-Feng Zhao, Xiao-Jing Kang, Hong-Juan Wang, Juan Zhao,  and Xiong-Ming Pu
36614-36621
Abstract  |  PDF  |  HTML  |  Order a Reprint

Plasma lipidomics profiling identified lipid biomarkers in distinguishing early-stage breast cancer from benign lesions

Plasma lipidomics profiling identified lipid biomarkers in distinguishing early-stage breast cancer from benign lesions

https://doi.org/10.18632/oncotarget.9124

Xiaoli Chen, Hankui Chen, Meiyu Dai, Junmei Ai, Yan Li, Brett Mahon, Shengming Dai,  and Youping Deng
36622-36631
Abstract  |  PDF  |  HTML  |  Order a Reprint

Stratified analysis reveals chemokine-like factor (CKLF) as a potential prognostic marker in the MSI-immune consensus molecular subtype CMS1 of colorectal cancer

Stratified analysis reveals chemokine-like factor (CKLF) as a potential prognostic marker in the MSI-immune consensus molecular subtype CMS1 of colorectal cancer

https://doi.org/10.18632/oncotarget.9126

Philip D. Dunne, Paul G. O’Reilly, Helen G. Coleman, Ronan T. Gray, Daniel B. Longley, Patrick G. Johnston, Manuel Salto-Tellez, Mark Lawler,  and Darragh G. McArt
36632-36644
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circulating tumor cells as a prognostic and predictive marker in gastrointestinal stromal tumors: a prospective study

Circulating tumor cells as a prognostic and predictive marker in gastrointestinal stromal tumors: a prospective study

https://doi.org/10.18632/oncotarget.9128

Qiang Li, Xiaofei Zhi, Jianping Zhou, Ran Tao, Jiaxuan Zhang, Peisheng Chen, Oluf Dimitri Røe, Luning Sun,  and Lilin Ma
36645-36654
Abstract  |  PDF  |  HTML  |  Order a Reprint

The anti-apoptotic and prognostic value of fibroblast growth factor 9 in gastric cancer

The anti-apoptotic and prognostic value of fibroblast growth factor 9 in gastric cancer

https://doi.org/10.18632/oncotarget.9131

Chuanli Ren, Hui Chen, Chongxu Han, Deyuan Fu, Fuan Wang, Daxin Wang, Li Ma, Lin Zhou,  and Dongsheng Han
36655-36665
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeting carbonic anhydrase IX improves the anti-cancer efficacy of mTOR inhibitors

Targeting carbonic anhydrase IX improves the anti-cancer efficacy of mTOR inhibitors

https://doi.org/10.18632/oncotarget.9134

Seraina Faes, Anne Planche, Emilie Uldry, Tania Santoro, Catherine Pythoud, Jean-Christophe Stehle, Janine Horlbeck, Igor Letovanec, Nicolo Riggi, Dipak Datta, Nicolas Demartines,  and Olivier Dormond
36666-36680
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

OTUB1-catalyzed deubiquitination of FOXM1 facilitates tumor progression and predicts a poor prognosis in ovarian cancer

OTUB1-catalyzed deubiquitination of FOXM1 facilitates tumor progression and predicts a poor prognosis in ovarian cancer

https://doi.org/10.18632/oncotarget.9160

Yiqin Wang, Xianrong Zhou, Midie Xu, Weiwei Weng, Qiongyan Zhang, Yusi Yang, Ping Wei,  and Xiang Du
36681-36697
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Matricellular protein CCN1 mediates doxorubicin-induced cardiomyopathy in mice

Matricellular protein CCN1 mediates doxorubicin-induced cardiomyopathy in mice

https://doi.org/10.18632/oncotarget.9162

Pei-Ling Hsu,  and Fan-E Mo
36698-36710
Abstract  |  PDF  |  HTML  |  Order a Reprint

RMEL3, a novel BRAFV600E-associated long noncoding RNA, is required for MAPK and PI3K signaling in melanoma

RMEL3, a novel BRAFV600E-associated long noncoding RNA, is required for MAPK and PI3K signaling in melanoma

https://doi.org/10.18632/oncotarget.9164

Lucas Goedert, Cristiano G. Pereira, Jason Roszik, Jessica R. Plaça, Cibele Cardoso, Guo Chen, Wanleng Deng, Vashisht Gopal Yennu-Nanda, Wilson A. Silva Jr., Michael A. Davies,  and Enilza M. Espreafico
36711-36718
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Soluble factors from stellate cells induce pancreatic cancer cell proliferation via Nrf2-activated metabolic reprogramming and ROS detoxification

Soluble factors from stellate cells induce pancreatic cancer cell proliferation via Nrf2-activated metabolic reprogramming and ROS detoxification

https://doi.org/10.18632/oncotarget.9165

Yuan Seng Wu, Chung Yeng Looi, Kavita S. Subramaniam, Atsushi Masamune,  and Ivy Chung
36719-36732
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Serum microRNA expression signatures as novel noninvasive biomarkers for prediction and prognosis of muscle-invasive bladder cancer

Serum microRNA expression signatures as novel noninvasive biomarkers for prediction and prognosis of muscle-invasive bladder cancer

https://doi.org/10.18632/oncotarget.9166

Xiumei Jiang, Lutao Du, Weili Duan, Rui Wang, Keqiang Yan, Lili Wang, Juan Li, Guixi Zheng, Xin Zhang, Yongmei Yang,  and Chuanxin Wang
36733-36742
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-507 inhibits the migration and invasion of human breastcancer cells through Flt-1 suppression

MiR-507 inhibits the migration and invasion of human breastcancer cells through Flt-1 suppression

https://doi.org/10.18632/oncotarget.9163

Liyan Jia, Wei Liu, Bo Cao, Hongli Li,  and Chonggao Yin
36743-36754
Abstract  |  PDF  |  HTML  |  Order a Reprint

Altered methylation of glucosylceramide synthase promoter regulates its expression and associates with acquired multidrug resistance in invasive ductal breast cancer

Altered methylation of glucosylceramide synthase promoter regulates its expression and associates with acquired multidrug resistance in invasive ductal breast cancer

https://doi.org/10.18632/oncotarget.9337

Jiannan Liu, Xiaofang Zhang, Aina Liu, Daoping Zhang, Yi Su, Ying Liu, Dong You, Leilei Yuan, Xiangshuo Kong, Xiaodan Wang,  and Ping Sun
36755-36766
Abstract  |  PDF  |  HTML  |  Order a Reprint

Des-gamma-carboxy prothrombin antagonizes the effects of Sorafenib on human hepatocellular carcinoma through activation of the Raf/MEK/ERK and PI3K/Akt/mTOR signaling pathways

Des-gamma-carboxy prothrombin antagonizes the effects of Sorafenib on human hepatocellular carcinoma through activation of the Raf/MEK/ERK and PI3K/Akt/mTOR signaling pathways

https://doi.org/10.18632/oncotarget.9168

Shu-Xiang Cui, Wen-Na Shi, Zhi-Yu Song, Shu-Qing Wang, Xin-Feng Yu, Zu-Hua Gao,  and Xian-Jun Qu
36767-36782
Abstract  |  PDF  |  HTML  |  Order a Reprint

Epstein-Barr virus encoded miR-BART11 promotes inflammation-induced carcinogenesis by targeting FOXP1

Epstein-Barr virus encoded miR-BART11 promotes inflammation-induced carcinogenesis by targeting FOXP1

https://doi.org/10.18632/oncotarget.9170

Yali Song, Xiaoling Li, Zhaoyang Zeng, Qiao Li, Zhaojian Gong, Qianjin Liao, Xiayu Li, Pan Chen, Bo Xiang, Wenling Zhang, Fang Xiong, Yanhong Zhou, Ming Zhou, Jian Ma, Yong Li, Xiang Chen, Guiyuan Li,  and Wei Xiong
36783-36799
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

C-terminus of MUC16 activates Wnt signaling pathway through its interaction with β-catenin to promote tumorigenesis and metastasis

C-terminus of MUC16 activates Wnt signaling pathway through its interaction with β-catenin to promote tumorigenesis and metastasis

https://doi.org/10.18632/oncotarget.9191

Qi Liu, Zhen Cheng, Lianzhong Luo, Yun Yang, Zhenzhu Zhang, Huanhuan Ma, Tao Chen, Xi Huang, Shu-Yong Lin, Meijun Jin, Qinxi Li,  and Xiaotong Li
36800-36813
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Androgen/androgen receptor axis maintains and promotes cancer cell stemness through direct activation of Nanog transcription in hepatocellular carcinoma

Androgen/androgen receptor axis maintains and promotes cancer cell stemness through direct activation of Nanog transcription in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9192

Lupin Jiang, Juanjuan Shan, Junjie Shen, Yanzhou Wang, Ping Yan, Limei Liu, Wenxu Zhao, Yanmin Xu, Wei Zhu, Li Su, Jun Chen, Feifei Cheng, Hong Yao, Huicheng Xu, Cheng Qian,  and Zhiqing Liang
36814-36828
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GDNF secreted from adipose-derived stem cells stimulates VEGF-independent angiogenesis

GDNF secreted from adipose-derived stem cells stimulates VEGF-independent angiogenesis

https://doi.org/10.18632/oncotarget.9208

Zhaohui Zhong, Huiying Gu, Jirun Peng, Wenzheng Wang, Brian H. Johnstone, Keith L. March, Martin R. Farlow,  and Yansheng Du
36829-36841
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Crosstalk between CCL7 and CCR3 promotes metastasis of colon cancer cells via ERK-JNK signaling pathways

Crosstalk between CCL7 and CCR3 promotes metastasis of colon cancer cells via ERK-JNK signaling pathways

https://doi.org/10.18632/oncotarget.9209

Yeo Song Lee, So-Young Kim, Su Jeong Song, Hye Kyung Hong, Yura Lee, Bo Young Oh, Woo Yong Lee,  and Yong Beom Cho
36842-36853
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Repression of TCF3/E2A contributes to Hodgkin lymphomagenesis

Repression of TCF3/E2A contributes to Hodgkin lymphomagenesis

https://doi.org/10.18632/oncotarget.9210

Hanfeng Guan, Linka Xie, Thomas Wirth,  and Alexey Ushmorov
36854-36864
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JWA loss promotes cell migration and cytoskeletal rearrangement by affecting HER2 expression and identifies a high-risk subgroup of HER2-positive gastric carcinoma patients

JWA loss promotes cell migration and cytoskeletal rearrangement by affecting HER2 expression and identifies a high-risk subgroup of HER2-positive gastric carcinoma patients

https://doi.org/10.18632/oncotarget.9211

Jing Qian, Weiyou Zhu, Keming Wang, Lin Ma, Jin Xu, Tongpeng Xu, Oluf Dimitri Røe, Aiping Li, Jianwei Zhou,  and Yongqian Shu
36865-36884
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Pathway analysis of expression-related SNPs on genome-wide association study of basal cell carcinoma

Pathway analysis of expression-related SNPs on genome-wide association study of basal cell carcinoma

https://doi.org/10.18632/oncotarget.9212

Xin Li, Liming Liang, Immaculata De Vivo, Jean Y. Tang,  and Jiali Han
36885-36895
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CCL5 promotes VEGF-C production and induces lymphangiogenesis by suppressing miR-507 in human chondrosarcoma cells

CCL5 promotes VEGF-C production and induces lymphangiogenesis by suppressing miR-507 in human chondrosarcoma cells

https://doi.org/10.18632/oncotarget.9213

Li-Hong Wang, Chih-Yang Lin, Shih-Chia Liu, Guan-Ting Liu, Yen-Ling Chen, Jih-Jung Chen, Chia-Han Chan, Ting-Yi Lin, Chi-Kuan Chen, Guo-Hong Xu, Shiou-Sheng Chen, Chih-Hsin Tang,  and Shih-Wei Wang
36896-36908
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Methylation-mediated repression of microRNA-129-2 suppresses cell aggressiveness by inhibiting high mobility group box 1 in human hepatocellular carcinoma

Methylation-mediated repression of microRNA-129-2 suppresses cell aggressiveness by inhibiting high mobility group box 1 in human hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9377

Zhikui Liu, Changwei Dou, Bowen Yao, Meng Xu, Linglong Ding, Yufeng Wang, Yuli Jia, Qing Li, Hongyong Zhang, Kangsheng Tu, Tao Song,  and Qingguang Liu
36909-36923
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Intestine-specific homeobox (ISX) upregulates E2F1 expression and related oncogenic activities in HCC

Intestine-specific homeobox (ISX) upregulates E2F1 expression and related oncogenic activities in HCC

https://doi.org/10.18632/oncotarget.9228

Shen-Nien Wang, Li-Ting Wang, Ding-Ping Sun, Chee-Yin Chai, Edward Hsi, Hsing-Tao Kuo, Kazunari K. Yokoyama,  and Shih-Hsien Hsu
36924-36939
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Estrogen regulates miRNA expression: implication of estrogen receptor and miR-124/AKT2 in tumor growth and angiogenesis

Estrogen regulates miRNA expression: implication of estrogen receptor and miR-124/AKT2 in tumor growth and angiogenesis

https://doi.org/10.18632/oncotarget.9230

Cheng-Fei Jiang, Dong-Mei Li, Zhu-Mei Shi, Lin Wang, Min-Min Liu, Xin Ge, Xue Liu, Ying-Chen Qian, Yi-Yang Wen, Lin-Lin Zhen, Jie Lin, Ling-Zhi Liu,  and Bing-Hua Jiang
36940-36955
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The AXL receptor tyrosine kinase is associated with adverse prognosis and distant metastasis in esophageal squamous cell carcinoma

The AXL receptor tyrosine kinase is associated with adverse prognosis and distant metastasis in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.9231

Min-Shu Hsieh, Pei-Wen Yang, Li-Fan Wong,  and Jang-Ming Lee
36956-36970
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Post-translational regulation of the cleaved fragment of Par-4 in ovarian and endometrial cancer cells

Post-translational regulation of the cleaved fragment of Par-4 in ovarian and endometrial cancer cells

https://doi.org/10.18632/oncotarget.9235

Kevin Brasseur, François Fabi, Pascal Adam, Sophie Parent, Laurent Lessard,  and Eric Asselin
36971-36987
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Paracrine regulation of matrix metalloproteinases contributes to cancer cell invasion by hepatocellular carcinoma-secreted 14-3-3σ

Paracrine regulation of matrix metalloproteinases contributes to cancer cell invasion by hepatocellular carcinoma-secreted 14-3-3σ

https://doi.org/10.18632/oncotarget.9234

Chia-Chia Liu, Tzu-Ching Chang, Yi-Ting Lin, Yen-Ling Yu, Bor-Sheng Ko, Li-Ying Sung,  and Jun-Yang Liou
36988-36999
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Glutaredoxin 3 promotes nasopharyngeal carcinoma growth and metastasis via EGFR/Akt pathway and independent of ROS

Glutaredoxin 3 promotes nasopharyngeal carcinoma growth and metastasis via EGFR/Akt pathway and independent of ROS

https://doi.org/10.18632/oncotarget.9454

Feng He, Lili Wei, Wenqi Luo, Zhipeng Liao, Bo Li, Xiaoying Zhou, Xue Xiao, Jingping You, Yufeng Chen, Shixing Zheng, Ping Li, Mariko Murata, Guangwu Huang,  and Zhe Zhang
37000-37012
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation

The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation

https://doi.org/10.18632/oncotarget.9455

Christophe Le Clorennec, Yassamine Lazrek, Olivier Dubreuil, Christel Larbouret, Marie-Alix Poul, Philippe Mondon, Gerry Melino, André Pèlegrin,  and Thierry Chardès
37013-37029
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TAT-IL-24-KDEL-induced apoptosis is inhibited by survivin but restored by the small molecular survivin inhibitor, YM155, in cancer cells

TAT-IL-24-KDEL-induced apoptosis is inhibited by survivin but restored by the small molecular survivin inhibitor, YM155, in cancer cells

https://doi.org/10.18632/oncotarget.9458

Jian Zhang, Rui Xu, Xinyi Tao, Yuguo Dong, Xinxin Lv, Aiyou Sun,  and Dongzhi Wei
37030-37042
Abstract  |  PDF  |  HTML  |  Order a Reprint

Metabolomic screening of pre-diagnostic serum samples identifies association between α- and γ-tocopherols and glioblastoma risk

Metabolomic screening of pre-diagnostic serum samples identifies association between α- and γ-tocopherols and glioblastoma risk

https://doi.org/10.18632/oncotarget.9242

Benny Björkblom, Carl Wibom, Pär Jonsson, Lina Mörén, Ulrika Andersson, Tom Børge Johannesen, Hilde Langseth, Henrik Antti,  and Beatrice Melin
37043-37053
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MAPK activation and HRAS mutation identified in pituitary spindle cell oncocytoma

MAPK activation and HRAS mutation identified in pituitary spindle cell oncocytoma

https://doi.org/10.18632/oncotarget.9244

Michael B. Miller, Wenya Linda Bi, Lori A. Ramkissoon, Yun Jee Kang, Malak Abedalthagafi, David S. Knoff, Pankaj K. Agarwalla, Patrick Y. Wen, David A. Reardon, Brian M. Alexander, Edward R. Laws Jr., Ian F. Dunn, Rameen Beroukhim, Keith L. Ligon,  and Shakti H. Ramkissoon
37054-37063
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution

Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution

https://doi.org/10.18632/oncotarget.9245

Delphine Denoyer, Helen B. Pearson, Sharnel A.S. Clatworthy, Zoe M. Smith, Paul S. Francis, Roxana M. Llanos, Irene Volitakis, Wayne A. Phillips, Peter M. Meggyesy, Shashank Masaldan,  and Michael A. Cater
37064-37080
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Exploiting macrophages as targeted carrier to guide nanoparticles into glioma

Exploiting macrophages as targeted carrier to guide nanoparticles into glioma

https://doi.org/10.18632/oncotarget.9464

Liang Pang, Jing Qin, Limei Han, Wenjie Zhao, Jianming Liang, Zhongyi Xie, Pei Yang,  and Jianxin Wang
37081-37091
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Integrity of a HPV11 infection cell model and identification of (-)-Epigallocatechin-3-gallate as a potential HPV11 inhibitor

Integrity of a HPV11 infection cell model and identification of (-)-Epigallocatechin-3-gallate as a potential HPV11 inhibitor

https://doi.org/10.18632/oncotarget.9249

Yang Sun, Xinyu Li, Shasha Song, Yongfang Wang,  and Heng Gu
37092-37102
Abstract  |  PDF  |  HTML  |  Order a Reprint

The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth

The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth

https://doi.org/10.18632/oncotarget.9466

Sebastian Trousil, Maciej Kaliszczak, Zachary Schug, Quang-De Nguyen, Giampaolo Tomasi, Rosy Favicchio, Diana Brickute, Robin Fortt, Frazer J. Twyman, Laurence Carroll, Andrew Kalusa, Naveenan Navaratnam, Thomas Adejumo, David Carling, Eyal Gottlieb,  and Eric O. Aboagye
37103-37120
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pseudomonas aeruginosa mannose-sensitive hemagglutinin inhibits proliferation and invasion via the PTEN/AKT pathway in HeLa cells

Pseudomonas aeruginosa mannose-sensitive hemagglutinin inhibits proliferation and invasion via the PTEN/AKT pathway in HeLa cells

https://doi.org/10.18632/oncotarget.9467

Tie-qiu Yin, Xuan Ou-yang, Fang-yan Jiao, Lu-ping Huang, Xu-dong Tang,  and Bi-qiong Ren
37121-37131
Abstract  |  PDF  |  HTML  |  Order a Reprint

Genome-wide DNA methylation profiles altered by Helicobacter pylori in gastric mucosa and blood leukocyte DNA

Genome-wide DNA methylation profiles altered by Helicobacter pylori in gastric mucosa and blood leukocyte DNA

https://doi.org/10.18632/oncotarget.9469

Yang Zhang, Xin-ran Zhang, Jong-lyul Park, Jong-hwan Kim, Lian Zhang, Jun-ling Ma, Wei-dong Liu, Da-jun Deng, Wei-cheng You, Yong-sung Kim,  and Kai-feng Pan
37132-37144
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Met and its ligand HGF are associated with clinical outcome in breast cancer

Met and its ligand HGF are associated with clinical outcome in breast cancer

https://doi.org/10.18632/oncotarget.9268

Cynthia Veenstra, Gizeh Pérez-Tenorio, Anna Stelling, Elin Karlsson, Sanam Mirwani Mirwani, Bo Nordensköljd, Tommy Fornander,  and Olle Stål
37145-37159
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sensitive and affordable diagnostic assay for the quantitative detection of anaplastic lymphoma kinase (ALK) alterations in patients with non-small cell lung cancer

Sensitive and affordable diagnostic assay for the quantitative detection of anaplastic lymphoma kinase (ALK) alterations in patients with non-small cell lung cancer

https://doi.org/10.18632/oncotarget.9471

Elisa Dama, Micol Tillhon, Giovanni Bertalot, Francesca de Santis, Flavia Troglio, Simona Pessina, Antonio Passaro, Salvatore Pece, Filippo de Marinis, Patrizia Dell’Orto, Giuseppe Viale, Lorenzo Spaggiari, Pier Paolo Di Fiore, Fabrizio Bianchi, Massimo Barberis,  and Manuela Vecchi
37160-37176
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mouse double minute 2 (MDM2) upregulates Snail expression and induces epithelial-to-mesenchymal transition in breast cancer cells in vitro and in vivo

Mouse double minute 2 (MDM2) upregulates Snail expression and induces epithelial-to-mesenchymal transition in breast cancer cells in vitro and in vivo

https://doi.org/10.18632/oncotarget.9287

Xiangdong Lu, Caiyun Yan, Yi Huang, Dongmin Shi, Ziyi Fu, Jinrong Qiu,  and Yongmei Yin
37177-37191
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Bmi1 inhibition enhances the sensitivity of pancreatic cancer cells to gemcitabine

Bmi1 inhibition enhances the sensitivity of pancreatic cancer cells to gemcitabine

https://doi.org/10.18632/oncotarget.9293

Tao Yin, Zhengle Zhang, Bin Cao, Qingke Duan, Pengfei Shi, Hengqiang Zhao, Soriba Naby Camara, Qiang Shen,  and Chunyou Wang
37192-37204
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical impact of L1CAM expression measured on the transcriptome level in ovarian cancer

Clinical impact of L1CAM expression measured on the transcriptome level in ovarian cancer

https://doi.org/10.18632/oncotarget.9291

Samira Abdel Azim, Michaela Duggan-Peer, Susanne Sprung, Daniel Reimer, Heidi Fiegl, Afschin Soleiman, Christian Marth,  and Alain G. Zeimet
37205-37214
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GADD45β induction by S-adenosylmethionine inhibits hepatocellular carcinoma cell proliferation during acute ischemia-hypoxia

GADD45β induction by S-adenosylmethionine inhibits hepatocellular carcinoma cell proliferation during acute ischemia-hypoxia

https://doi.org/10.18632/oncotarget.9295

Ding Ma, Baiyong Shen, Varun Seewoo, Hui Tong, Weiping Yang, Xi Cheng, Zhijian Jin, Chenghong Peng,  and Weihua Qiu
37215-37225
Abstract  |  PDF  |  HTML  |  Order a Reprint

Proteomic analysis of stromal proteins in different stages of colorectal cancer establishes Tenascin-C as a stromal biomarker for colorectal cancer metastasis

Proteomic analysis of stromal proteins in different stages of colorectal cancer establishes Tenascin-C as a stromal biomarker for colorectal cancer metastasis

https://doi.org/10.18632/oncotarget.9362

Maoyu Li, Fang Peng, Guoqing Li, Yang Fu, Ying Huang, Zhuchu Chen,  and Yongheng Chen
37226-37237
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevated ZC3H15 increases HCC growth and predicts poor survival after surgical resection

Elevated ZC3H15 increases HCC growth and predicts poor survival after surgical resection

https://doi.org/10.18632/oncotarget.9361

Bei-ge Jiang, Zheng-hua Wan, Jian Huang, Li-mei Li, Hui Liu, Si-yuan Fu, Yuan Yang, Jin Zhang, Shen-xian Yuan, Ruo-yu Wang, Yun Yang, Fang-ming Gu, Li-wei Dong, Ze-ya Pan,  and Wei-ping Zhou
37238-37249
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A unique set of 6 circulating microRNAs for early detection of non-small cell lung cancer

A unique set of 6 circulating microRNAs for early detection of non-small cell lung cancer

https://doi.org/10.18632/oncotarget.9363

Ann Rita Halvorsen, Maria Bjaanæs, Marissa LeBlanc, Are M. Holm, Nils Bolstad, Luis Rubio, Juan Carlos Peñalver, José Cervera, Julia Cruz Mojarrieta, Jose Antonio López-Guerrero, Odd Terje Brustugun,  and Åslaug Helland
37250-37259
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Phosphorylation of E-cadherin at threonine 790 by protein kinase Cδ reduces β-catenin binding and suppresses the function of E-cadherin

Phosphorylation of E-cadherin at threonine 790 by protein kinase Cδ reduces β-catenin binding and suppresses the function of E-cadherin

https://doi.org/10.18632/oncotarget.9403

Chien-Lin Chen, Shu-Hui Wang, Po-Chao Chan, Meng-Ru Shen,  and Hong-Chen Chen
37260-37276
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

The role of neoadjuvant chemotherapy for resectable colorectal liver metastases: a systematic review and meta-analysis

The role of neoadjuvant chemotherapy for resectable colorectal liver metastases: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.8671

Wei Liu, Jian-Guo Zhou, Yi Sun, Lei Zhang,  and Bao-Cai Xing
37277-37287
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Implementation of a rapid learning platform: Predicting 2-year survival in laryngeal carcinoma patients in a clinical setting

Implementation of a rapid learning platform: Predicting 2-year survival in laryngeal carcinoma patients in a clinical setting

https://doi.org/10.18632/oncotarget.8755

Tim Lustberg, Michael Bailey, David I. Thwaites, Alexis Miller, Martin Carolan, Lois Holloway, Emmanuel Rios Velazquez, Frank Hoebers,  and Andre Dekker
37288-37296
Abstract  |  PDF  |  HTML  |  Order a Reprint

Neoadjuvant modified TPF (docetaxel, cisplatin, fluorouracil) for patients unfit to standard TPF in locally advanced head and neck squamous cell carcinoma: a study of 48 patients

Neoadjuvant modified TPF (docetaxel, cisplatin, fluorouracil) for patients unfit to standard TPF in locally advanced head and neck squamous cell carcinoma: a study of 48 patients

https://doi.org/10.18632/oncotarget.8934

Jérôme Fayette, Clara Fontaine-Delaruelle, Alexis Ambrun, Clémentine Daveau, Marc Poupart, Antoine Ramade, Philippe Zrounba, Eve-Marie Neidhardt, Julien Péron, Alpha Diallo,  and Philippe Céruse
37297-37304
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic significance of cancer family history for patients with gastric cancer: a single center experience from China

Prognostic significance of cancer family history for patients with gastric cancer: a single center experience from China

https://doi.org/10.18632/oncotarget.9032

Xiaowen Liu, Hong Cai, Lin Yu, Hua Huang, Ziwen Long,  and Yanong Wang
37305-37318
Abstract  |  PDF  |  HTML  |  Order a Reprint

Establishment and validation of a prognostic nomogram for patients with resectable perihilar cholangiocarcinoma

Establishment and validation of a prognostic nomogram for patients with resectable perihilar cholangiocarcinoma

https://doi.org/10.18632/oncotarget.9104

Peizhan Chen, Bin Li, Yan Zhu, Wei Chen, Xin Liu, Mian Li, Xiaohua Duan, Bin Yi, Jinghan Wang, Chen Liu, Xiangji Luo, Xiaoguang Li, Jingquan Li, Lijian Liang, Xiaoyu Yin, Hui Wang,  and Xiaoqing Jiang
37319-37330
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reviews

The clinical value of aberrant epigenetic changes of DNA damage repair genes in human cancer

The clinical value of aberrant epigenetic changes of DNA damage repair genes in human cancer

https://doi.org/10.18632/oncotarget.7949

Dan Gao, James G. Herman,  and Mingzhou Guo
37331-37346
Abstract  |  PDF  |  HTML  |  Order a Reprint

Post-translational modification-regulated leukocyte adhesion and migration

Post-translational modification-regulated leukocyte adhesion and migration

https://doi.org/10.18632/oncotarget.8135

Jia Tong Loh,  and I-hsin Su
37347-37360
Abstract  |  PDF  |  HTML  |  Order a Reprint

The significant prognostic value of circulating tumor cells in triple-negative breast cancer: a meta-analysis

The significant prognostic value of circulating tumor cells in triple-negative breast cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.8156

Yan-jun Lu, Peng Wang, Xiong Wang, Jing Peng, Yao-wu Zhu,  and Na Shen
37361-37369
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Biomarker development in MET-targeted therapy

Biomarker development in MET-targeted therapy

https://doi.org/10.18632/oncotarget.8276

Yanni Zhang, Zhiqiang Du,  and Mingqiang Zhang
37370-37389
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dietary fat intake and ovarian cancer risk: a meta-analysis of epidemiological studies

Dietary fat intake and ovarian cancer risk: a meta-analysis of epidemiological studies

https://doi.org/10.18632/oncotarget.8940

Wenlong Qiu, Heng Lu, Yana Qi,  and Xiuwen Wang
37390-37406
Abstract  |  PDF  |  HTML  |  Order a Reprint


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