Oncotarget

Vol 7, No 22

May 31, 2016

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The impact of the MYB-NFIB fusion protooncogene in vivo. See Mikse et al.

Table of Contents

Priority Research Papers

Inhibitors of Rho kinase (ROCK) signaling revert the malignant phenotype of breast cancer cells in 3D context

Inhibitors of Rho kinase (ROCK) signaling revert the malignant phenotype of breast cancer cells in 3D context

https://doi.org/10.18632/oncotarget.9395

Masahiro Matsubara,  and Mina J. Bissell
31602-31622
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Cooperation of Nutlin-3a and a Wip1 inhibitor to induce p53 activity

Cooperation of Nutlin-3a and a Wip1 inhibitor to induce p53 activity

https://doi.org/10.18632/oncotarget.9302

Anusha Sriraman, Marija Radovanovic, Magdalena Wienken, Zeynab Najafova, Yizhu Li,  and Matthias Dobbelstein
31623-31638
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Telomerase inhibitor imetelstat has preclinical activity across the spectrum of non-small cell lung cancer oncogenotypes in a telomere length dependent manner

Telomerase inhibitor imetelstat has preclinical activity across the spectrum of non-small cell lung cancer oncogenotypes in a telomere length dependent manner

https://doi.org/10.18632/oncotarget.9335

Robin E. Frink, Michael Peyton, Joan H. Schiller, Adi F. Gazdar, Jerry W. Shay,  and John D. Minna
31639-31651
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CXCL16 regulates cisplatin-induced acute kidney injury

CXCL16 regulates cisplatin-induced acute kidney injury

https://doi.org/10.18632/oncotarget.9386

Hua Liang, Zhengmao Zhang, Liqun He,  and Yanlin Wang
31652-31662
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microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-κB

microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-κB

https://doi.org/10.18632/oncotarget.9421

Keith M. Giles, Rikki A.M. Brown, Clarissa Ganda, Melissa J. Podgorny, Patrick A. Candy, Larissa C. Wintle, Kirsty L. Richardson, Felicity C. Kalinowski, Lisa M. Stuart, Michael R. Epis, Nikolas K. Haass, Meenhard Herlyn,  and Peter J. Leedman
31663-31680
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The impact of the MYB-NFIB fusion proto-oncogene in vivo

The impact of the MYB-NFIB fusion proto-oncogene in vivo

https://doi.org/10.18632/oncotarget.9426

Oliver R. Mikse, Jeremy H. Tchaicha, Esra A. Akbay, Liang Chen, Roderick T. Bronson, Peter S. Hammerman,  and Kwok-Kin Wong
31681-31688
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Research Papers: Gerotarget (Focus on Aging)

Impact of SORL1 genetic variations on MRI markers in non-demented elders

Impact of SORL1 genetic variations on MRI markers in non-demented elders

https://doi.org/10.18632/oncotarget.9300

Rui-Hua Yin, Jun Li, Lin Tan, Hui-Fu Wang, Meng-Shan Tan, Wan-Jiang Yu, Chen-Chen Tan, Jin-Tai Yu, Lan Tan,  and Alzheimer’s Disease Neuroimaging Initiative
31689-31698
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Research Papers: Pathology

Limited effect of lymph node status on the metastatic pattern in colorectal cancer

Limited effect of lymph node status on the metastatic pattern in colorectal cancer

https://doi.org/10.18632/oncotarget.9064

Nikki Knijn, Felice N. van Erning, Lucy I.H. Overbeek, Cornelis J.A. Punt, Valery E.P.P. Lemmens, Niek Hugen,  and Iris D. Nagtegaal
31699-31707
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Dichloroacetate treatment improves mitochondrial metabolism and reduces brain injury in neonatal mice

Dichloroacetate treatment improves mitochondrial metabolism and reduces brain injury in neonatal mice

https://doi.org/10.18632/oncotarget.9150

Yanyan Sun, Tao Li, Cuicui Xie, Yaodong Zhang, Kai Zhou, Xiaoyang Wang, Klas Blomgren,  and Changlian Zhu
31708-31722
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Phosphorylation of gH2AX as a novel prognostic biomarker for laryngoesophageal dysfunction-free survival

Phosphorylation of gH2AX as a novel prognostic biomarker for laryngoesophageal dysfunction-free survival

https://doi.org/10.18632/oncotarget.9172

María José de Miguel-Luken, Manuel Chaves-Conde, Begoña Quintana, Alicia Menoyo, Isabel Tirado, Verónica de Miguel-Luken, Jerónimo Pachón, David Chinchón, Vladimir Suarez,  and Amancio Carnero
31723-31737
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Galectin-1 is essential for efficient liver regeneration following hepatectomy

Galectin-1 is essential for efficient liver regeneration following hepatectomy

https://doi.org/10.18632/oncotarget.9194

Tamara Potikha, Ezra Ella, Juan P. Cerliani, Lina Mizrahi, Orit Pappo, Gabriel A. Rabinovich, Eithan Galun,  and Daniel S. Goldenberg
31738-31754
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Research Papers: Immunology

The co-stimulatory molecule B7-H3 promotes the epithelial-mesenchymal transition in colorectal cancer

The co-stimulatory molecule B7-H3 promotes the epithelial-mesenchymal transition in colorectal cancer

https://doi.org/10.18632/oncotarget.9035

Bo Jiang, Ting Zhang, Fen Liu, Zhangzhang Sun, Hanping Shi, Dong Hua,  and Chen Yang
31755-31771
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Subanesthetic isoflurane relieves zymosan-induced neutrophil inflammatory response by targeting NMDA glutamate receptor and Toll-like receptor 2 signaling

Subanesthetic isoflurane relieves zymosan-induced neutrophil inflammatory response by targeting NMDA glutamate receptor and Toll-like receptor 2 signaling

https://doi.org/10.18632/oncotarget.9091

Jun-Tang Li, Wei-Qi Wang, Ling Wang, Ning-Ning Liu, Ya-Li Zhao, Xiao-Shan Zhu, Qin-Qin Liu, Chun-Fang Gao, An-Gang Yang,  and Lin-Tao Jia
31772-31789
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Caffeic acid ameliorates colitis in association with increased Akkermansia population in the gut microbiota of mice

Caffeic acid ameliorates colitis in association with increased Akkermansia population in the gut microbiota of mice

https://doi.org/10.18632/oncotarget.9306

Zhan Zhang, Xinyue Wu, Shuyuan Cao, Li Wang, Di Wang, Hui Yang, Yiming Feng, Shoulin Wang,  and Lei Li
31790-31799
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Anti-inflammatory effects of interleukin-23 receptor cytokine-binding homology region rebalance T cell distribution in rodent collagen-induced arthritis

Anti-inflammatory effects of interleukin-23 receptor cytokine-binding homology region rebalance T cell distribution in rodent collagen-induced arthritis

https://doi.org/10.18632/oncotarget.9309

Wei Guo, Dongmei Yu, Xin Wang, Cheng Luo, Yucong Chen, Wen Lei, Chen Wang, Yaoyao Ge, Wenyao Xue, Qiqi Tian, Xiangdong Gao,  and Wenbing Yao
31800-31813
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Research Papers

A new agent developed by biotransformation of polyphyllin VII inhibits chemoresistance in breast cancer

A new agent developed by biotransformation of polyphyllin VII inhibits chemoresistance in breast cancer

https://doi.org/10.18632/oncotarget.6674

Dong-Xu He, Guo-Hong Li, Xiao-Ting Gu, Liang Zhang, Ai-Qin Mao, Juan Wei, De-Quan Liu, Gui-Yang Shi,  and Xin Ma
31814-31824
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MDM2 and P53 polymorphisms contribute together to the risk and survival of prostate cancer

MDM2 and P53 polymorphisms contribute together to the risk and survival of prostate cancer

https://doi.org/10.18632/oncotarget.3923

Li Xue, Xiujuan Han, Rongrong Liu, Ziming Wang, Hecheng Li, Qi Chen, Peng Zhang, Zhenlong Wang,  and Tie Chong
31825-31831
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Inhibition of c-FLIPL expression by miRNA-708 increases the sensitivity of renal cancer cells to anti-cancer drugs

Inhibition of c-FLIPL expression by miRNA-708 increases the sensitivity of renal cancer cells to anti-cancer drugs

https://doi.org/10.18632/oncotarget.7149

Eun-Ae Kim, Sang-Woo Kim, Jehyun Nam, Eon-Gi Sung, In-Hwan Song, Joo-Young Kim, Taeg Kyu Kwon,  and Tae-Jin Lee
31832-31846
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Cancer-selective cytotoxic Ca2+ overload in acute myeloid leukemia cells and attenuation of disease progression in mice by synergistically acting polyphenols curcumin and carnosic acid

Cancer-selective cytotoxic Ca2+ overload in acute myeloid leukemia cells and attenuation of disease progression in mice by synergistically acting polyphenols curcumin and carnosic acid

https://doi.org/10.18632/oncotarget.7240

Stella Pesakhov, Matan Nachliely, Zeev Barvish, Nasma Aqaqe, Bar Schwartzman, Elena Voronov, Yoav Sharoni, George P. Studzinski, Daniel Fishman,  and Michael Danilenko
31847-31861
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Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing

Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing

https://doi.org/10.18632/oncotarget.7364

Davide Degli Esposti, Hector Hernandez-Vargas, Catherine Voegele, Nora Fernandez-Jimenez, Nathalie Forey, Brigitte Bancel, Florence Le Calvez-Kelm, James McKay, Philippe Merle,  and Zdenko Herceg
31862-31877
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Prostate tumor overexpressed-1, in conjunction with human papillomavirus status, predicts outcome in early-stage human laryngeal squamous cell carcinoma

Prostate tumor overexpressed-1, in conjunction with human papillomavirus status, predicts outcome in early-stage human laryngeal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.8103

Lin Yang, Hongzhi Wang, Yan Wang, Zhenyu He, Haiyang Chen, Shaobo Liang, Shasha He, Shu Wu, Libing Song,  and Yong Chen
31878-31891
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A positive feedback loop involving EGFR/Akt/mTORC1 and IKK/NF-κB regulates head and neck squamous cell carcinoma proliferation

A positive feedback loop involving EGFR/Akt/mTORC1 and IKK/NF-κB regulates head and neck squamous cell carcinoma proliferation

https://doi.org/10.18632/oncotarget.7441

Zhipeng Li, Zejia Yang, Antonino Passaniti, Rena G. Lapidus, Xuefeng Liu, Kevin J. Cullen,  and Han C. Dan
31892-31906
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Cell line with endogenous EGFRvIII expression is a suitable model for research and drug development purposes

Cell line with endogenous EGFRvIII expression is a suitable model for research and drug development purposes

https://doi.org/10.18632/oncotarget.8201

Wojciech J. Stec, Kamila Rosiak, Paulina Siejka, Joanna Peciak, Marta Popeda, Mateusz Banaszczyk, Roza Pawlowska, Cezary Treda, Krystyna Hulas-Bigoszewska, Sylwester Piaskowski, Ewelina Stoczynska-Fidelus,  and Piotr Rieske
31907-31925
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic role of lymphocyte to monocyte ratio for patients with cancer: evidence from a systematic review and meta-analysis

Prognostic role of lymphocyte to monocyte ratio for patients with cancer: evidence from a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.7876

Liangyou Gu, Hongzhao Li, Luyao Chen, Xin Ma, Xintao Li, Yu Gao, Yu Zhang, Yongpeng Xie,  and Xu Zhang
31926-31942
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Characterization of cervical cancer stem cell-like cells: phenotyping, stemness, and human papilloma virus co-receptor expression

Characterization of cervical cancer stem cell-like cells: phenotyping, stemness, and human papilloma virus co-receptor expression

https://doi.org/10.18632/oncotarget.8218

Elizabeth Ortiz-Sánchez, Luz Santiago-López, Verónica B. Cruz-Domínguez, Mariel E. Toledo-Guzmán, Daniel Hernández-Cueto, Saé Muñiz-Hernández, Efraín Garrido, David Cantú De León,  and Alejandro García-Carrancá
31943-31954
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Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma

Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma

https://doi.org/10.18632/oncotarget.7454

Sébastien Bougnaud, Anna Golebiewska, Anaïs Oudin, Olivier Keunen, Patrick N. Harter, Lisa Mäder, Francisco Azuaje, Sabrina Fritah, Daniel Stieber, Tony Kaoma, Laurent Vallar, Nicolaas H.C. Brons, Thomas Daubon, Hrvoje Miletic, Terje Sundstrøm, Christel Herold-Mende, Michel Mittelbronn, Rolf Bjerkvig,  and Simone P. Niclou
31955-31971
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The association between the TERT rs2736100 AC genotype and reduced risk of upper tract urothelial carcinomas in a Han Chinese population

The association between the TERT rs2736100 AC genotype and reduced risk of upper tract urothelial carcinomas in a Han Chinese population

https://doi.org/10.18632/oncotarget.7777

Xiaotian Yuan, Yan Meng, Ping Li, Nan Ge, Feng Kong, Liu Yang, Magnus Björkholm, Shengtian Zhao,  and Dawei Xu
31972-31979
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P53 activation inhibits all types of hematopoietic progenitors and all stages of megakaryopoiesis

P53 activation inhibits all types of hematopoietic progenitors and all stages of megakaryopoiesis

https://doi.org/10.18632/oncotarget.7881

Emna Mahfoudhi, Larissa Lordier, Caroline Marty, Jiajia Pan, Anita Roy, Lydia Roy, Philippe Rameau, Salem Abbes, Najet Debili, Hana Raslova, Yunhua Chang, Laurent Debussche, William Vainchenker,  and Isabelle Plo
31980-31992
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-371-5p targets SOX2 in gastric cancer

MicroRNA-371-5p targets SOX2 in gastric cancer

https://doi.org/10.18632/oncotarget.8289

Yu-Ji Li, Ming Dong, Fan-Min Kong, Jian-Ping Zhou, Dong Liang,  and Huan-Zhou Xue
31993-32005
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Response of brain metastasis from lung cancer patients to an oral nutraceutical product containing silibinin

Response of brain metastasis from lung cancer patients to an oral nutraceutical product containing silibinin

https://doi.org/10.18632/oncotarget.7900

Joaquim Bosch-Barrera, Elia Sais, Noemí Cañete, Jordi Marruecos, Elisabet Cuyàs, Angel Izquierdo, Rut Porta, Manel Haro, Joan Brunet, Salvador Pedraza,  and Javier A. Menendez
32006-32014
Abstract  |  PDF  |  HTML  |  Order a Reprint

IL-10 control of CD11c+ myeloid cells is essential to maintain immune homeostasis in the small and large intestine

IL-10 control of CD11c+ myeloid cells is essential to maintain immune homeostasis in the small and large intestine

https://doi.org/10.18632/oncotarget.8337

Mathilde J.H. Girard-Madoux, Juliane L. Ober-Blöbaum, Léa M.M. Costes, Junda M. Kel, Dicky J. Lindenbergh-Kortleve, Inge Brouwers-Haspels, Astrid P. Heikema, Janneke N. Samsom,  and Björn E. Clausen
32015-32030
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

STAT3 and NF-κB cooperatively control in vitro spontaneous apoptosis and poor chemo-responsiveness in patients with chronic lymphocytic leukemia

STAT3 and NF-κB cooperatively control in vitro spontaneous apoptosis and poor chemo-responsiveness in patients with chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.8672

Feng-Ting Liu, Li Jia, Ping Wang, Huaqing Wang, Timothy W. Farren,  and Samir G. Agrawal
32031-32045
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reactive oxygen species induced by therapeutic CD20 antibodies inhibit natural killer cell-mediated antibody-dependent cellular cytotoxicity against primary CLL cells

Reactive oxygen species induced by therapeutic CD20 antibodies inhibit natural killer cell-mediated antibody-dependent cellular cytotoxicity against primary CLL cells

https://doi.org/10.18632/oncotarget.8769

Olle Werlenius, Johan Aurelius, Alexander Hallner, Ali A. Akhiani, Maria Simpanen, Anna Martner, Per-Ola Andersson, Kristoffer Hellstrand,  and Fredrik B. Thorén
32046-32053
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A novel agent exerts antitumor activity in breast cancer cells by targeting mitochondrial complex II

A novel agent exerts antitumor activity in breast cancer cells by targeting mitochondrial complex II

https://doi.org/10.18632/oncotarget.8410

Liang Wang, Xiaojing Zhang, Guozhen Cui, Judy Yuet‑Wa Chan, Li Wang, Chuwen Li, Luchen Shan, Changjiang Xu, Qingwen Zhang, Yuqiang Wang, Lijun Di,  and Simon Ming‑Yuen Lee
32054-32064
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mutational spectrum and risk stratification of intermediate-risk acute myeloid leukemia patients based on next-generation sequencing

Mutational spectrum and risk stratification of intermediate-risk acute myeloid leukemia patients based on next-generation sequencing

https://doi.org/10.18632/oncotarget.7028

Bianhong Wang, Yangyang Liu, Guangyuan Hou, Lili Wang, Na Lv, Yuanyuan Xu, Yihan Xu, Xiuli Wang, Zhaoling Xuan, Yu Jing, Honghua Li, Xiangshu Jin, Ailing Deng, Li Wang, Xiaoning Gao, Liping Dou, Junbin Liang, Chongjian Chen, Yonghui Li,  and Li Yu
32065-32078
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The Wilms Tumor-1 (WT1) rs16754 polymorphism is a prognostic factor in acute myeloid leukemia (AML): a meta-analysis

The Wilms Tumor-1 (WT1) rs16754 polymorphism is a prognostic factor in acute myeloid leukemia (AML): a meta-analysis

https://doi.org/10.18632/oncotarget.8117

Jianting Long, Shi Fang, Qiangsheng Dai, Xiaolian Liu, Wanshou Zhu,  and Shenming Wang
32079-32087
Abstract  |  PDF  |  HTML  |  Order a Reprint

TR4 nuclear receptor enhances the cisplatin chemo-sensitivity via altering the ATF3 expression to better suppress HCC cell growth

TR4 nuclear receptor enhances the cisplatin chemo-sensitivity via altering the ATF3 expression to better suppress HCC cell growth

https://doi.org/10.18632/oncotarget.8525

Jiliang Shen, Hui Lin, Gonghui Li, Ren-An Jin, Liang Shi, Mingming Chen, Chawnshang Chang,  and Xiujun Cai
32088-32099
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Lysyl oxidase family activity promotes resistance of pancreatic ductal adenocarcinoma to chemotherapy by limiting the intratumoral anticancer drug distribution

Lysyl oxidase family activity promotes resistance of pancreatic ductal adenocarcinoma to chemotherapy by limiting the intratumoral anticancer drug distribution

https://doi.org/10.18632/oncotarget.8527

Benjamin Le Calvé, Audrey Griveau, David Vindrieux, Raphaël Maréchal, Clotilde Wiel, Magali Svrcek, Johann Gout, Lamia Azzi, Léa Payen, Jérôme Cros, Christelle de la Fouchardière, Pierre Dubus, Jérôme Guitton, Laurent Bartholin, Jean-Baptiste Bachet,  and David Bernard
32100-32112
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical significance of PD-L1 and PD-L2 copy number gains in non-small-cell lung cancer

Clinical significance of PD-L1 and PD-L2 copy number gains in non-small-cell lung cancer

https://doi.org/10.18632/oncotarget.8528

Yusuke Inoue, Katsuhiro Yoshimura, Kazutaka Mori, Nobuya Kurabe, Tomoaki Kahyo, Hiroki Mori, Akikazu Kawase, Masayuki Tanahashi, Hiroshi Ogawa, Naoki Inui, Kazuhito Funai, Kazuya Shinmura, Hiroshi Niwa, Takafumi Suda,  and Haruhiko Sugimura
32113-32128
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Deregulation of IGF-binding proteins -2 and -5 contributes to the development of endocrine resistant breast cancer in vitro

Deregulation of IGF-binding proteins -2 and -5 contributes to the development of endocrine resistant breast cancer in vitro

https://doi.org/10.18632/oncotarget.8534

Yousef Hawsawi, Matthew P. Humphries, Alexander Wright, Angelene Berwick, Mike Shires, Hanaa Al-Kharobi, Reem El-Gendy, Maria Jove, Chris Twelves, Valerie Speirs,  and James Beattie
32129-32143
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Intraoperative imaging of folate receptor alpha positive ovarian and breast cancer using the tumor specific agent EC17

Intraoperative imaging of folate receptor alpha positive ovarian and breast cancer using the tumor specific agent EC17

https://doi.org/10.18632/oncotarget.8282

Quirijn R.J.G. Tummers, Charlotte E.S. Hoogstins, Katja N. Gaarenstroom, Cor D. de Kroon, Mariette I.E. van Poelgeest, Jaap Vuyk, Tjalling Bosse, Vincent T.H.B.M. Smit, Cornelis J.H. van de Velde, Adam F. Cohen, Philip S. Low, Jacobus Burggraaf,  and Alexander L. Vahrmeijer
32144-32155
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Osteopontin is a multi-faceted pro-tumorigenic driver for central nervous system lymphoma

Osteopontin is a multi-faceted pro-tumorigenic driver for central nervous system lymphoma

https://doi.org/10.18632/oncotarget.8537

Qiu Yushi, Zhimin Li, Christina A. Von Roemeling, Heike Doeppler, Laura A. Marlow, Betty Y.S. Kim, Derek C. Radisky, Peter Storz, John A. Copland,  and Han W. Tun
32156-32171
Abstract  |  PDF  |  HTML  |  Order a Reprint

The DNA resection protein CtIP promotes mammary tumorigenesis

The DNA resection protein CtIP promotes mammary tumorigenesis

https://doi.org/10.18632/oncotarget.8605

Colleen R. Reczek, Reena Shakya, Yana Miteva, Matthias Szabolcs, Thomas Ludwig,  and Richard Baer
32172-32183
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Quercetin and doxorubicin co-encapsulated biotin receptor-targeting nanoparticles for minimizing drug resistance in breast cancer

Quercetin and doxorubicin co-encapsulated biotin receptor-targeting nanoparticles for minimizing drug resistance in breast cancer

https://doi.org/10.18632/oncotarget.8607

Li Lv, Chunxia Liu, Chuxiong Chen, Xiaoxia Yu, Guanghui Chen, Yonghui Shi, Fengchao Qin, Jiebin Ou, Kaifeng Qiu,  and Guocheng Li
32184-32199
Abstract  |  PDF  |  HTML  |  Order a Reprint

Repurposed drug screen identifies cardiac glycosides as inhibitors of TGF-β-induced cancer-associated fibroblast differentiation

Repurposed drug screen identifies cardiac glycosides as inhibitors of TGF-β-induced cancer-associated fibroblast differentiation

https://doi.org/10.18632/oncotarget.8609

David T. Coleman, Alana L. Gray, Charles A. Stephens, Matthew L. Scott,  and James A. Cardelli
32200-32209
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Niclosamide enhances abiraterone treatment via inhibition of androgen receptor variants in castration resistant prostate cancer

Niclosamide enhances abiraterone treatment via inhibition of androgen receptor variants in castration resistant prostate cancer

https://doi.org/10.18632/oncotarget.8493

Chengfei Liu, Cameron Armstrong, Yezi Zhu, Wei Lou,  and Allen C. Gao
32210-32220
Abstract  |  PDF  |  HTML  |  Order a Reprint

Matrix stiffness-mediated effects on stemness characteristics occurring in HCC cells

Matrix stiffness-mediated effects on stemness characteristics occurring in HCC cells

https://doi.org/10.18632/oncotarget.8515

Yang You, Qiongdan Zheng, Yinying Dong, Xiaoying Xie, Yaohui Wang, Sifan Wu, Lan Zhang, Yingcong Wang, Tongchun Xue, Zhiming Wang, Rongxin Chen, Yanhong Wang, Jiefeng Cui,  and Zhenggang Ren
32221-32231
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Avoiding drug resistance through extended drug target interfaces: a case for stapled peptides

Avoiding drug resistance through extended drug target interfaces: a case for stapled peptides

https://doi.org/10.18632/oncotarget.8572

Siau Jia Wei, Sharon Chee, Larisa Yurlova, David Lane, Chandra Verma, Christopher Brown,  and Farid Ghadessy
32232-32246
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The oleocanthal-based homovanillyl sinapate as a novel c-Met inhibitor

The oleocanthal-based homovanillyl sinapate as a novel c-Met inhibitor

https://doi.org/10.18632/oncotarget.8681

Mohamed M. Mohyeldin, Mohamed R. Akl, Hassan Y. Ebrahim, Ana Maria Dragoi, Samantha Dykes, James A. Cardelli,  and Khalid A. El Sayed
32247-32273
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

DNA polymerase iota (Pol ι) promotes invasion and metastasis of esophageal squamous cell carcinoma

DNA polymerase iota (Pol ι) promotes invasion and metastasis of esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.8580

Shitao Zou, Zeng-Fu Shang, Biao Liu, Shuyu Zhang, Jinchang Wu, Min Huang, Wei-Qun Ding,  and Jundong Zhou
32274-32285
Abstract  |  PDF  |  HTML  |  Order a Reprint

A KSHV microRNA enhances viral latency and induces angiogenesis by targeting GRK2 to activate the CXCR2/AKT pathway

A KSHV microRNA enhances viral latency and induces angiogenesis by targeting GRK2 to activate the CXCR2/AKT pathway

https://doi.org/10.18632/oncotarget.8591

Wan Li, Xuemei Jia, Chenyou Shen, Mi Zhang, Jingyun Xu, Yuancui Shang, Kaixiang Zhu, Minmin Hu, Qin Yan, Di Qin, Myung-Shin Lee, Jianzhong Zhu, Hongmei Lu, Brian J. Krueger, Rolf Renne, Shou-Jiang Gao,  and Chun Lu
32286-32305
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Visfatin is involved in promotion of colorectal carcinoma malignancy through an inducing EMT mechanism

Visfatin is involved in promotion of colorectal carcinoma malignancy through an inducing EMT mechanism

https://doi.org/10.18632/oncotarget.8615

Jing Yang, Kun Zhang, Haixing Song, Mingbo Wu, Jingyi Li, Ziyi Yong, Sheng Jiang, Xi Kuang,  and Tao Zhang
32306-32317
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Programmed death-ligand 1 overexpression is a prognostic marker for aggressive papillary thyroid cancer and its variants

Programmed death-ligand 1 overexpression is a prognostic marker for aggressive papillary thyroid cancer and its variants

https://doi.org/10.18632/oncotarget.8698

Subrata Chowdhury, Joe Veyhl, Fatima Jessa, Olena Polyakova, Ahmed Alenzi, Christina MacMillan, Ranju Ralhan,  and Paul G. Walfish
32318-32328
Abstract  |  PDF  |  HTML  |  Order a Reprint

Gene silencing of indoleamine 2,3-dioxygenase 2 in melanoma cells induces apoptosis through the suppression of NAD+ and inhibits in vivo tumor growth

Gene silencing of indoleamine 2,3-dioxygenase 2 in melanoma cells induces apoptosis through the suppression of NAD+ and inhibits in vivo tumor growth

https://doi.org/10.18632/oncotarget.8617

Yanling Liu, Yujuan Zhang, Xiufen Zheng, Xusheng Zhang, Hongmei Wang, Qin Li, Keng Yuan, Nanjing Zhou, Yanrong Yu, Na Song, Jiamin Fu,  and Weiping Min
32329-32340
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GABRA3 promotes lymphatic metastasis in lung adenocarcinoma by mediating upregulation of matrix metalloproteinases

GABRA3 promotes lymphatic metastasis in lung adenocarcinoma by mediating upregulation of matrix metalloproteinases

https://doi.org/10.18632/oncotarget.8700

Liping Liu, Chenglin Yang, Jianfei Shen, Liyan Huang, Weixuan Lin, Hailing Tang, Wenhua Liang, Wenlong Shao, Haibo Zhang,  and Jianxing He
32341-32350
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

BLM promotes the activation of Fanconi Anemia signaling pathway

BLM promotes the activation of Fanconi Anemia signaling pathway

https://doi.org/10.18632/oncotarget.8707

Jayabal Panneerselvam, Hong Wang, Jun Zhang, Raymond Che, Herbert Yu,  and Peiwen Fei
32351-32361
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reduction of microRNA-184 by E6 oncoprotein confers cisplatin resistance in lung cancer via increasing Bcl-2

Reduction of microRNA-184 by E6 oncoprotein confers cisplatin resistance in lung cancer via increasing Bcl-2

https://doi.org/10.18632/oncotarget.8708

Min-Che Tung, Po-Lin Lin, Ya-Wen Cheng, De-Wei Wu, Sauh-Der Yeh, Chi-Yi Chen,  and Huei Lee
32362-32374
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis

Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis

https://doi.org/10.18632/oncotarget.8632

Marta Anna Kowalik, Giulia Guzzo, Andrea Morandi, Andrea Perra, Silvia Menegon, Ionica Masgras, Elena Trevisan, Maria Maddalena Angioni, Francesca Fornari, Luca Quagliata, Giovanna Maria Ledda-Columbano, Laura Gramantieri, Luigi Terracciano, Silvia Giordano, Paola Chiarugi, Andrea Rasola,  and Amedeo Columbano
32375-32393
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Predicting cancer-relevant proteins using an improved molecular similarity ensemble approach

Predicting cancer-relevant proteins using an improved molecular similarity ensemble approach

https://doi.org/10.18632/oncotarget.8716

Bin Zhou, Qi Sun,  and De-Xin Kong
32394-32407
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Manganese superoxide dismutase mediates anoikis resistance and tumor metastasis in nasopharyngeal carcinoma

Manganese superoxide dismutase mediates anoikis resistance and tumor metastasis in nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.8717

Shuai Li, Yuling Mao, Ti Zhou, Chuanghua Luo, Jinye Xie, Weiwei Qi, Zhonghan Yang, JianXing Ma, Guoquan Gao,  and Xia Yang
32408-32420
Abstract  |  PDF  |  HTML  |  Order a Reprint

miR-1207-5p suppresses lung cancer growth and metastasis by targeting CSF1

miR-1207-5p suppresses lung cancer growth and metastasis by targeting CSF1

https://doi.org/10.18632/oncotarget.8718

Wei Dang, Zailong Qin, Songqing Fan, Qiuyuan Wen, Yuanjun Lu, Jia Wang, Xuemei Zhang, Lingyu Wei, Wei He, Qiurong Ye, Qun Yan, Guiyuan Li,  and Jian Ma
32421-32432
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comprehensive analysis of lncRNA expression profiles reveals a novel lncRNA signature to discriminate nonequivalent outcomes in patients with ovarian cancer

Comprehensive analysis of lncRNA expression profiles reveals a novel lncRNA signature to discriminate nonequivalent outcomes in patients with ovarian cancer

https://doi.org/10.18632/oncotarget.8653

Meng Zhou, Yanying Sun, Yifan Sun, Wanying Xu, Zhaoyue Zhang, Hengqiang Zhao, Zhaohua Zhong,  and Jie Sun
32433-32448
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Necrosis-inducing peptide has the beneficial effect on killing tumor cells through neuropilin (NRP-1) targeting

Necrosis-inducing peptide has the beneficial effect on killing tumor cells through neuropilin (NRP-1) targeting

https://doi.org/10.18632/oncotarget.8719

Ji-Young Kim, Ji-Hae Han, Geon Park, Young-Woo Seo, Cheol-Won Yun, Byung-Chul Lee, Jeehyeon Bae, Ae Ran Moon,  and Tae-Hyoung Kim
32449-32461
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Aspirin prevents colorectal cancer metastasis in mice by splitting the crosstalk between platelets and tumor cells

Aspirin prevents colorectal cancer metastasis in mice by splitting the crosstalk between platelets and tumor cells

https://doi.org/10.18632/oncotarget.8655

Paloma Guillem-Llobat, Melania Dovizio, Annalisa Bruno, Emanuela Ricciotti, Valerio Cufino, Angela Sacco, Rosalia Grande, Sara Alberti, Vincenzo Arena, Mariangela Cirillo, Carlo Patrono, Garret A. FitzGerald, Dieter Steinhilber, Alessandro Sgambato,  and Paola Patrignani
32462-32477
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The long non-coding RNA ANRIL promotes proliferation and cell cycle progression and inhibits apoptosis and senescence in epithelial ovarian cancer

The long non-coding RNA ANRIL promotes proliferation and cell cycle progression and inhibits apoptosis and senescence in epithelial ovarian cancer

https://doi.org/10.18632/oncotarget.8744

Jun‑jun Qiu, Yan Wang, Ying‑lei Liu, Ying Zhang, Jing‑xin Ding,  and Ke‑qin Hua
32478-32492
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hepatocyte SLAMF3 reduced specifically the multidrugs resistance protein MRP-1 and increases HCC cells sensitization to anti-cancer drugs

Hepatocyte SLAMF3 reduced specifically the multidrugs resistance protein MRP-1 and increases HCC cells sensitization to anti-cancer drugs

https://doi.org/10.18632/oncotarget.8679

Grégory Fouquet, Véronique Debuysscher, Hakim Ouled-Haddou, Mélanie Simoes Eugenio, Baptiste Demey, Amrathlal Rabbind Singh, Christèle Ossart, Mohammed Al Bagami, Jean-Marc Regimbeau, Eric Nguyen-Khac, Mickael Naassila, Ingrid Marcq,  and Hicham Bouhlal
32493-32503
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical significance of monitoring ESR1 mutations in circulating cell-free DNA in estrogen receptor positive breast cancer patients

Clinical significance of monitoring ESR1 mutations in circulating cell-free DNA in estrogen receptor positive breast cancer patients

https://doi.org/10.18632/oncotarget.8839

Takashi Takeshita, Yutaka Yamamoto, Mutsuko Yamamoto-Ibusuki, Toko Inao, Aiko Sueta, Saori Fujiwara, Yoko Omoto,  and Hirotaka Iwase
32504-32518
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cardiotoxicity as indicated by LVEF and troponin T sensitivity following two anthracycline-based regimens in lymphoma: Results from a randomized prospective clinical trial

Cardiotoxicity as indicated by LVEF and troponin T sensitivity following two anthracycline-based regimens in lymphoma: Results from a randomized prospective clinical trial

https://doi.org/10.18632/oncotarget.8685

Kai Xue, Juan J. Gu, Qunling Zhang, Xiaojian Liu, Jiachen Wang, Xiao-qiu Li, Jianfeng Luo, Francisco J. Hernandez-Ilizaliturri, Stanley F. Fernandez, Myron S. Czuczman, Junning Cao, Xiaonan Hong,  and Ye Guo
32519-32531
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Phase I clinical study of RG7356, an anti-CD44 humanized antibody, in patients with acute myeloid leukemia

Phase I clinical study of RG7356, an anti-CD44 humanized antibody, in patients with acute myeloid leukemia

https://doi.org/10.18632/oncotarget.8687

Norbert Vey, Jacques Delaunay, Giovanni Martinelli, Walter Fiedler, Emmanuel Raffoux, Thomas Prebet, Carlos Gomez-Roca, Cristina Papayannidis, Maxim Kebenko, Peter Paschka, Randolph Christen, Ernesto Guarin, Ann-Marie Bröske, Monika Baehner, Michael Brewster, Antje-Christine Walz, Francesca Michielin, Valeria Runza, Valerie Meresse,  and Christian Recher
32532-32542
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

UBE2D3 gene overexpression increases radiosensitivity of EC109 esophageal cancer cells in vitro and in vivo

UBE2D3 gene overexpression increases radiosensitivity of EC109 esophageal cancer cells in vitro and in vivo

https://doi.org/10.18632/oncotarget.8869

Xiaojia Gao, Wenbo Wang, Hui Yang, Lin Wu, Zhongshi He, Shuliang Zhou, Hong Zhao, Zhenming Fu, Fuxiang Zhou,  and Yunfeng Zhou
32543-32553
Abstract  |  PDF  |  HTML  |  Order a Reprint

The toxic effects and possible mechanisms of Bisphenol A on oocyte maturation of porcine in vitro

The toxic effects and possible mechanisms of Bisphenol A on oocyte maturation of porcine in vitro

https://doi.org/10.18632/oncotarget.8689

Teng Wang, Jun Han, Xing Duan, Bo Xiong, Xiang-Shun Cui, Nam-Hyung Kim, Hong-Lin Liu,  and Shao-Chen Sun
32554-32565
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Inulanolide A as a new dual inhibitor of NFAT1-MDM2 pathway for breast cancer therapy

Inulanolide A as a new dual inhibitor of NFAT1-MDM2 pathway for breast cancer therapy

https://doi.org/10.18632/oncotarget.8873

Jiang-Jiang Qin, Wei Wang, Sushanta Sarkar, Sukesh Voruganti, Rajesh Agarwal,  and Ruiwen Zhang
32566-32578
Abstract  |  PDF  |  HTML  |  Order a Reprint

Sequential intensified conditioning followed by prophylactic DLI could reduce relapse of refractory acute leukemia after allo-HSCT

Sequential intensified conditioning followed by prophylactic DLI could reduce relapse of refractory acute leukemia after allo-HSCT

https://doi.org/10.18632/oncotarget.8691

Li Xuan, Zhiping Fan, Yu Zhang, Hongsheng Zhou, Fen Huang, Min Dai, Danian Nie, Dongjun Lin, Na Xu, Xutao Guo, Qianli Jiang, Jing Sun, Yang Xiao,  and Qifa Liu
32579-32591
Abstract  |  PDF  |  HTML  |  Order a Reprint

The levels of serine proteases in colon tissue interstitial fluid and serum serve as an indicator of colorectal cancer progression

The levels of serine proteases in colon tissue interstitial fluid and serum serve as an indicator of colorectal cancer progression

https://doi.org/10.18632/oncotarget.8693

Yingying Xie, Lechuang Chen, Xiaolei Lv, Guixue Hou, Yang Wang, Cuicui Jiang, Hongxia Zhu, Ningzhi Xu, Lin Wu, Xiaomin Lou,  and Siqi Liu
32592-32606
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Potential diagnostic and prognostic marker dimethylglycine dehydrogenase (DMGDH) suppresses hepatocellular carcinoma metastasis in vitro and in vivo

Potential diagnostic and prognostic marker dimethylglycine dehydrogenase (DMGDH) suppresses hepatocellular carcinoma metastasis in vitro and in vivo

https://doi.org/10.18632/oncotarget.8927

Gang Liu, Guojun Hou, Liang Li, Yixue Li, Weiping Zhou,  and Lei Liu
32607-32616
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression and prognostic significance of CCL11/CCR3 in glioblastoma

Expression and prognostic significance of CCL11/CCR3 in glioblastoma

https://doi.org/10.18632/oncotarget.8958

Min Tian, Lina Chen, Li Ma, Dandan Wang, Bin Shao, Jianyu Wu, Hangyu Wu,  and Yimin Jin
32617-32627
Abstract  |  PDF  |  HTML  |  Order a Reprint

Epigenetic reader BRD4 inhibition as a therapeutic strategy to suppress E2F2-cell cycle regulation circuit in liver cancer

Epigenetic reader BRD4 inhibition as a therapeutic strategy to suppress E2F2-cell cycle regulation circuit in liver cancer

https://doi.org/10.18632/oncotarget.8701

Seong Hwi Hong, Jung Woo Eun, Sung Kyung Choi, Qingyu Shen, Wahn Soo Choi, Jeung-Whan Han, Suk Woo Nam,  and Jueng Soo You
32628-32640
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Characterization of selective and potent PI3Kδ inhibitor (PI3KDIN- 015) for B-Cell malignances

Characterization of selective and potent PI3Kδ inhibitor (PI3KDIN- 015) for B-Cell malignances

https://doi.org/10.18632/oncotarget.8702

Xiaochuan Liu, Aoli Wang, Xiaofei Liang, Cheng Chen, Juanjuan Liu, Zheng Zhao, Hong Wu, Yuanxin Deng, Li Wang, Beilei Wang, Jiaxin Wu, Feiyang Liu, Stacey M. Fernandes, Sophia Adamia, Richard M. Stone, Ilene A. Galinsky, Jennifer R. Brown, James D. Griffin, Shanchun Zhang, Teckpeng Loh, Xin Zhang, Wenchao Wang, Ellen L. Weisberg, Jing Liu,  and Qingsong Liu
32641-32651
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Downregulation of cyclin D1 sensitizes cancer cells to MDM2 antagonist Nutlin-3

Downregulation of cyclin D1 sensitizes cancer cells to MDM2 antagonist Nutlin-3

https://doi.org/10.18632/oncotarget.8999

Peipei Yang, Weicai Chen, Xuhui Li, Grant Eilers, Quan He, Lili Liu, Yeqing Wu, Yuehong Wu, Wei Yu, Jonathan A. Fletcher,  and Wen-Bin Ou
32652-32663
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Palmitoylation regulates the intracellular trafficking and stability of c-Met

Palmitoylation regulates the intracellular trafficking and stability of c-Met

https://doi.org/10.18632/oncotarget.8706

David T. Coleman, Alana L. Gray, Steven J. Kridel,  and James A. Cardelli
32664-32677
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MERTK as a novel therapeutic target in head and neck cancer

MERTK as a novel therapeutic target in head and neck cancer

https://doi.org/10.18632/oncotarget.8724

Anne von Mässenhausen, Christine Sanders, Britta Thewes, Mario Deng, Angela Queisser, Wenzel Vogel, Glen Kristiansen, Stefan Duensing, Andreas Schröck, Friedrich Bootz, Peter Brossart, Jutta Kirfel, Lynn Heasley, Johannes Brägelmann,  and Sven Perner
32678-32694
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Monocarboxylate transporter 1 contributes to growth factor-induced tumor cell migration independent of transporter activity

Monocarboxylate transporter 1 contributes to growth factor-induced tumor cell migration independent of transporter activity

https://doi.org/10.18632/oncotarget.9016

Alana L. Gray, David T. Coleman, Runhua Shi,  and James A. Cardelli
32695-32706
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Extracellular miR-1246 promotes lung cancer cell proliferation and enhances radioresistance by directly targeting DR5

Extracellular miR-1246 promotes lung cancer cell proliferation and enhances radioresistance by directly targeting DR5

https://doi.org/10.18632/oncotarget.9017

Dexiao Yuan, Jinping Xu, Juan Wang, Yan Pan, Jiamei Fu, Yang Bai, Jianghong Zhang,  and Chunlin Shao
32707-32722
Abstract  |  PDF  |  HTML  |  Order a Reprint

Increased B4GALT1 expression associates with adverse outcome in patients with non-metastatic clear cell renal cell carcinoma

Increased B4GALT1 expression associates with adverse outcome in patients with non-metastatic clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.8737

Huyang Xie, Yu Zhu, Huimin An, Hongkai Wang, Yao Zhu, Hangcheng Fu, Zewei Wang, Qiang Fu, Jiejie Xu,  and Dingwei Ye
32723-32730
Abstract  |  PDF  |  HTML  |  Order a Reprint

TP53 mutations and protein immunopositivity may predict for poor outcome but also for trastuzumab benefit in patients with early breast cancer treated in the adjuvant setting

TP53 mutations and protein immunopositivity may predict for poor outcome but also for trastuzumab benefit in patients with early breast cancer treated in the adjuvant setting

https://doi.org/10.18632/oncotarget.9022

George Fountzilas, Eleni Giannoulatou, Zoi Alexopoulou, Flora Zagouri, Eleni Timotheadou, Kyriaki Papadopoulou, Sotiris Lakis, Mattheos Bobos, Christos Poulios, Maria Sotiropoulou, Aggeliki Lyberopoulou, Helen Gogas, George Pentheroudakis, Dimitrios Pectasides, Angelos Koutras, Christos Christodoulou, Christos Papandreou, Epaminontas Samantas, Pavlos Papakostas, Paris Kosmidis, Dimitrios Bafaloukos, Charisios Karanikiotis, Meletios-Athanassios Dimopoulos,  and Vassiliki Kotoula
32731-32753
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HDAC1 promoted migration and invasion binding with TCF12 by promoting EMT progress in gallbladder cancer

HDAC1 promoted migration and invasion binding with TCF12 by promoting EMT progress in gallbladder cancer

https://doi.org/10.18632/oncotarget.8740

Junyi He, Sheng Shen, Weiqi Lu, Yuhong Zhou, Yingyong Hou, Yong Zhang, Ying Jiang, Houbao Liu,  and Yebo Shao
32754-32764
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic association of deleted in colorectal carcinoma variants with breast cancer risk: A case-control study

Genetic association of deleted in colorectal carcinoma variants with breast cancer risk: A case-control study

https://doi.org/10.18632/oncotarget.9024

Xinghan Liu, Xijing Wang, Sidney W. Fu, Meng Wang, Huafeng Kang, Haitao Guan, Shuqun Zhang, Xiaobin Ma, Shuai Lin, Kang Liu, Yanjing Feng, Cong Dai,  and Zhijun Dai
32765-32773
Abstract  |  PDF  |  HTML  |  Order a Reprint

COMMD7 is correlated with a novel NF-κB positive feedback loop in hepatocellular carcinoma

COMMD7 is correlated with a novel NF-κB positive feedback loop in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.9047

Lu Zheng, Chang-Lin Deng, Liang Wang, Xiao-Bing Huang, Nan You, Yi-Chen Tang, Ke Wu, Ping Liang, Na Mi,  and Jing Li
32774-32784
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Loss of PAX8 in high-grade serous ovarian cancer reduces cell survival despite unique modes of action in the fallopian tube and ovarian surface epithelium

Loss of PAX8 in high-grade serous ovarian cancer reduces cell survival despite unique modes of action in the fallopian tube and ovarian surface epithelium

https://doi.org/10.18632/oncotarget.9051

Laura H. Rodgers, Eoghainín Ó hAinmhire, Alexandria N. Young,  and Joanna E. Burdette
32785-32795
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MUC1 stimulates EGFR expression and function in endometrial cancer

MUC1 stimulates EGFR expression and function in endometrial cancer

https://doi.org/10.18632/oncotarget.8743

Brian J. Engel, Jessica L. Bowser, Russell R. Broaddus,  and Daniel D. Carson
32796-32809
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Functional characterization of a panel of high-grade serous ovarian cancer cell lines as representative experimental models of the disease

Functional characterization of a panel of high-grade serous ovarian cancer cell lines as representative experimental models of the disease

https://doi.org/10.18632/oncotarget.9053

James Haley, Sunil Tomar, Nicholas Pulliam, Sen Xiong, Susan M. Perkins, Adam R. Karpf, Sumegha Mitra, Kenneth P. Nephew,  and Anirban K. Mitra
32810-32820
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

QKI5-mediated alternative splicing of the histone variant macroH2A1 regulates gastric carcinogenesis

QKI5-mediated alternative splicing of the histone variant macroH2A1 regulates gastric carcinogenesis

https://doi.org/10.18632/oncotarget.8739

Feng Li, Ping Yi, Jingnan Pi, Lanfang Li, Jingyi Hui, Fang Wang, Aihua Liang,  and Jia Yu
32821-32834
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Predictive parameters for selection of electronic tissue compensation radiotherapy in early-stage breast cancer patients after breast-conserving surgery

Predictive parameters for selection of electronic tissue compensation radiotherapy in early-stage breast cancer patients after breast-conserving surgery

https://doi.org/10.18632/oncotarget.9054

Yanbo Song, Miao Zhang, Lu Gan, Xiaopin Chen, Tao Zhang, Ning J. Yue, Sharad Goyal, Bruce Haffty,  and Guosheng Ren
32835-32845
Abstract  |  PDF  |  HTML  |  Order a Reprint

Assessment of red blood cell distribution width as a prognostic marker in chronic lymphocytic leukemia

Assessment of red blood cell distribution width as a prognostic marker in chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.9055

Monika Podhorecka, Dorota Halicka, Agnieszka Szymczyk, Arkadiusz Macheta, Sylwia Chocholska, Marek Hus,  and Zbigniew Darzynkiewicz
32846-32853
Abstract  |  PDF  |  HTML  |  Order a Reprint

A novel TP53 variant (rs78378222 A > C) in the polyadenylation signal is associated with increased cancer susceptibility: evidence from a meta-analysis

A novel TP53 variant (rs78378222 A > C) in the polyadenylation signal is associated with increased cancer susceptibility: evidence from a meta-analysis

https://doi.org/10.18632/oncotarget.9056

Ying Wang, Xue-Song Wu, Jing He, Tianjiao Ma, Wei Lei,  and Zhen-Ya Shen
32854-32865
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Optical and nuclear imaging of glioblastoma with phosphatidylserine-targeted nanovesicles

Optical and nuclear imaging of glioblastoma with phosphatidylserine-targeted nanovesicles

https://doi.org/10.18632/oncotarget.8763

Víctor M. Blanco, Zhengtao Chu, Kathleen LaSance, Brian D. Gray, Koon Yan Pak, Therese Rider, Kenneth D. Greis,  and Xiaoyang Qi
32866-32875
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Fluid shear stress induces epithelial-mesenchymal transition (EMT) in Hep-2 cells

Fluid shear stress induces epithelial-mesenchymal transition (EMT) in Hep-2 cells

https://doi.org/10.18632/oncotarget.8765

Shuangfeng Liu, Fating Zhou, Yang Shen, Yingying Zhang, Hongmei Yin, Ye Zeng, Jingxia Liu, Zhiping Yan,  and Xiaoheng Liu
32876-32892
Abstract  |  PDF  |  HTML  |  Order a Reprint

Potential options for managing LOX+ ER- breast cancer patients

Potential options for managing LOX+ ER- breast cancer patients

https://doi.org/10.18632/oncotarget.9073

Yong Han, Shenyi Lian, Xingran Cui, Kexin Meng, Balázs Győrffy, Tao Jin,  and Dongsheng Huang
32893-32901
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Predictive microRNAs for lymph node metastasis in endoscopically resectable submucosal colorectal cancer

Predictive microRNAs for lymph node metastasis in endoscopically resectable submucosal colorectal cancer

https://doi.org/10.18632/oncotarget.8766

Chan Kwon Jung, Seung-Hyun Jung, Seon-Hee Yim, Ji-Han Jung, Hyun Joo Choi, Won-Kyung Kang, Sung-Won Park, Seong-Taek Oh, Jun-Gi Kim, Sug Hyung Lee,  and Yeun-Jun Chung
32902-32915
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

mTOR pathway activation is a favorable prognostic factor in human prostate adenocarcinoma

mTOR pathway activation is a favorable prognostic factor in human prostate adenocarcinoma

https://doi.org/10.18632/oncotarget.8767

Suzan Stelloo, Joyce Sanders, Ekaterina Nevedomskaya, Jeroen de Jong, Dennis Peters, Geert J.L.H. van Leenders, Guido Jenster, Andries M. Bergman,  and Wilbert Zwart
32916-32924
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Abundant PD-L1 expression in Epstein-Barr Virus-infected gastric cancers

Abundant PD-L1 expression in Epstein-Barr Virus-infected gastric cancers

https://doi.org/10.18632/oncotarget.9076

Sarah Derks, Xiaoyun Liao, Anna M. Chiaravalli, Xinsen Xu, M. Constanza Camargo, Enrico Solcia, Fausto Sessa, Tania Fleitas, Gordon J. Freeman, Scott J. Rodig, Charles S. Rabkin,  and Adam J. Bass
32925-32932
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Survival in acute myeloid leukemia is associated with NKp44 splice variants

Survival in acute myeloid leukemia is associated with NKp44 splice variants

https://doi.org/10.18632/oncotarget.8782

Avishai Shemesh, Michael Brusilovsky, Uzi Hadad, Omri Teltsh, Avishay Edri, Eitan Rubin, Kerry S. Campbell, Benyamin Rosental,  and Angel Porgador
32933-32945
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

UBAP2 negatively regulates the invasion of hepatocellular carcinoma cell by ubiquitinating and degradating Annexin A2

UBAP2 negatively regulates the invasion of hepatocellular carcinoma cell by ubiquitinating and degradating Annexin A2

https://doi.org/10.18632/oncotarget.8783

Dou-Sheng Bai, Chao Wu, Liu-Xiao Yang, Chi Zhang, Peng-Fei Zhang, Yi-Zhou He, Jia-Bin Cai, Zheng-Ji Song, Zhao-Ru Dong, Xiao-Yong Huang, Ai-Wu Ke,  and Guo-Ming Shi
32946-32955
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RB1 is the crucial target of the Merkel cell polyomavirus Large T antigen in Merkel cell carcinoma cells

RB1 is the crucial target of the Merkel cell polyomavirus Large T antigen in Merkel cell carcinoma cells

https://doi.org/10.18632/oncotarget.8793

Sonja Hesbacher, Lisa Pfitzer, Katharina Wiedorfer, Sabrina Angermeyer, Andreas Borst, Sebastian Haferkamp, Claus-Jürgen Scholz, Marion Wobser, David Schrama,  and Roland Houben
32956-32968
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SH003 represses tumor angiogenesis by blocking VEGF binding to VEGFR2

SH003 represses tumor angiogenesis by blocking VEGF binding to VEGFR2

https://doi.org/10.18632/oncotarget.8808

Hyeong Sim Choi, Min Kyoung Kim, Kangwook Lee, Kang Min Lee, Youn Kyung Choi, Yong Cheol Shin, Sung-Gook Cho,  and Seong-Gyu Ko
32969-32979
Abstract  |  PDF  |  HTML  |  Order a Reprint

Non-thermal plasma-induced apoptosis is modulated by ATR- and PARP1-mediated DNA damage responses and circadian clock

Non-thermal plasma-induced apoptosis is modulated by ATR- and PARP1-mediated DNA damage responses and circadian clock

https://doi.org/10.18632/oncotarget.9087

Ji Ye Choi, Hea Min Joh, Jeong-Min Park, Min Ji Kim, Tae Hun Chung,  and Tae-Hong Kang
32980-32989
Abstract  |  PDF  |  HTML  |  Order a Reprint

Synergistic combination of DT-13 and topotecan inhibits human gastric cancer via myosin IIA-induced endocytosis of EGF receptor in vitro and in vivo

Synergistic combination of DT-13 and topotecan inhibits human gastric cancer via myosin IIA-induced endocytosis of EGF receptor in vitro and in vivo

https://doi.org/10.18632/oncotarget.8843

Xiao-Wen Yu, Sensen Lin, Hong-Zhi Du, Ren-Ping Zhao, Shu-Yun Feng, Bo-Yang Yu, Lu-Yong Zhang, Rui-Ming Li, Chang-Min Qian, Xue-Jun Luo, Sheng-Tao Yuan,  and Li Sun
32990-33003
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gli-1/PI3K/AKT/NF-kB pathway mediates resistance to radiation and is a target for reversion of responses in refractory acute myeloid leukemia cells

Gli-1/PI3K/AKT/NF-kB pathway mediates resistance to radiation and is a target for reversion of responses in refractory acute myeloid leukemia cells

https://doi.org/10.18632/oncotarget.8844

Xiaodong Li, Fang Chen, Qiuhua Zhu, Bingjie Ding, Qingxiu Zhong, Kaikai Huang, Xuejie Jiang, Zhixiang Wang, Changxin Yin, Yufeng Zhu, Zhen Li,  and Fanyi Meng
33004-33015
Abstract  |  PDF  |  HTML  |  Order a Reprint

Quantitative assessment of the CD26+ leukemic stem cell compartment in chronic myeloid leukemia: patient-subgroups, prognostic impact, and technical aspects

Quantitative assessment of the CD26+ leukemic stem cell compartment in chronic myeloid leukemia: patient-subgroups, prognostic impact, and technical aspects

https://doi.org/10.18632/oncotarget.9108

Martin Culen, Marek Borsky, Veronika Nemethova, Filip Razga, Jiri Smejkal, Tomas Jurcek, Dana Dvorakova, Daniela Zackova, Barbora Weinbergerova, Lukas Semerad, Irina Sadovnik, Gregor Eisenwort, Harald Herrmann, Peter Valent, Jiri Mayer,  and Zdenek Racil
33016-33024
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Real-time monitoring of tumor progression and drug responses in a preclinical mouse model of prostate cancer

Real-time monitoring of tumor progression and drug responses in a preclinical mouse model of prostate cancer

https://doi.org/10.18632/oncotarget.8846

Peng Xu, Naijin Xu, Kai Guo, Abai Xu, Fumiaki Takenaka, Eiji Matsuura, Chunxiao Liu, Hiromi Kumon,  and Peng Huang
33025-33034
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High post-treatment serum levels of soluble programmed cell death ligand 1 predict early relapse and poor prognosis in extranodal NK/T cell lymphoma patients

High post-treatment serum levels of soluble programmed cell death ligand 1 predict early relapse and poor prognosis in extranodal NK/T cell lymphoma patients

https://doi.org/10.18632/oncotarget.8847

Hua Wang, Liang Wang, Wen-Jian Liu, Zhong-Jun Xia, Hui-Qiang Huang, Wen-Qi Jiang, Zhi-Ming Li,  and Yue Lu
33035-33045
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High efficacy of tumor-targeting Salmonella typhimurium A1-R on a doxorubicin- and dactolisib-resistant follicular dendritic-cell sarcoma in a patient-derived orthotopic xenograft PDOX nude mouse model

High efficacy of tumor-targeting Salmonella typhimurium A1-R on a doxorubicin- and dactolisib-resistant follicular dendritic-cell sarcoma in a patient-derived orthotopic xenograft PDOX nude mouse model

https://doi.org/10.18632/oncotarget.8848

Tasuku Kiyuna, Takashi Murakami, Yasunori Tome, Kei Kawaguchi, Kentaro Igarashi, Yong Zhang, Ming Zhao, Yunfeng Li, Michael Bouvet, Fuminori Kanaya, Arun Singh, Sarah Dry, Fritz C. Eilber,  and Robert M. Hoffman
33046-33054
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cisplatin selects for stem-like cells in osteosarcoma by activating Notch signaling

Cisplatin selects for stem-like cells in osteosarcoma by activating Notch signaling

https://doi.org/10.18632/oncotarget.8849

Ling Yu, Zhengfu Fan, Shuo Fang, Jian Yang, Tian Gao, Bruno M. Simões, Rachel Eyre, Weichun Guo,  and Robert B. Clarke
33055-33068
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tissue-specific conditional PKCε knockout mice: a model to precisely reveal PKCε functional role in initiation, promotion and progression of cancer

Tissue-specific conditional PKCε knockout mice: a model to precisely reveal PKCε functional role in initiation, promotion and progression of cancer

https://doi.org/10.18632/oncotarget.8850

Bilal Bin Hafeez, Louise Meske, Ashok Singh, Anupama Singh, Weixiong Zhong, Patricia Powers, Manorama John, Anne E. Griep,  and Ajit K. Verma
33069-33080
Abstract  |  PDF  |  HTML  |  Order a Reprint

A hypoxic signature marks tumors formed by disseminated tumor cells in the BALB-neuT mammary cancer model

A hypoxic signature marks tumors formed by disseminated tumor cells in the BALB-neuT mammary cancer model

https://doi.org/10.18632/oncotarget.8859

Aichi Msaki, Anna Pastò, Matteo Curtarello, Maddalena Arigoni, Giuseppina Barutello, Raffaele Adolfo Calogero, Marco Macagno, Federica Cavallo, Alberto Amadori,  and Stefano Indraccolo
33081-33095
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

NLRX1 suppresses tumorigenesis and attenuates histiocytic sarcoma through the negative regulation of NF-κB signaling

NLRX1 suppresses tumorigenesis and attenuates histiocytic sarcoma through the negative regulation of NF-κB signaling

https://doi.org/10.18632/oncotarget.8861

Sheryl Coutermarsh-Ott, Alysha Simmons, Vittoria Capria, Tanya LeRoith, Justin E. Wilson, Bettina Heid, Casandra W. Philipson, Qizhi Qin, Raquel Hontecillas-Magarzo, Josep Bassaganya-Riera, Jenny P-Y Ting, Nikolaos Dervisis,  and Irving C. Allen
33096-33110
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high levels of phospho-Src

Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high levels of phospho-Src

https://doi.org/10.18632/oncotarget.8880

Marco Perez, Antonio Lucena-Cacace, Luis Miguel Marín-Gómez, Javier Padillo-Ruiz, Maria Jose Robles-Frias, Carmen Saez, Rocio Garcia-Carbonero,  and Amancio Carnero
33111-33124
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hepatitis B virus X protein amplifies TGF-β promotion on HCC motility through down-regulating PPM1a

Hepatitis B virus X protein amplifies TGF-β promotion on HCC motility through down-regulating PPM1a

https://doi.org/10.18632/oncotarget.8884

Yuan Liu, Yong Xu, Hongxin Ma, Bo Wang, Leiqi Xu, Hualin Zhang, Xiaojia Song, Lifen Gao, Xiaohong Liang,  and Chunhong Ma
33125-33135
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR186 suppresses prostate cancer progression by targeting Twist1

miR186 suppresses prostate cancer progression by targeting Twist1

https://doi.org/10.18632/oncotarget.8887

Xian Zhao, Yanli Wang, Rong Deng, Hailong Zhang, Jinzhuo Dou, Haihua Yuan, Guofang Hou, Yuzhang Du, Qin Chen,  and Jianxiu Yu
33136-33151
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

AURKA induces EMT by regulating histone modification through Wnt/β-catenin and PI3K/Akt signaling pathway in gastric cancer

AURKA induces EMT by regulating histone modification through Wnt/β-catenin and PI3K/Akt signaling pathway in gastric cancer

https://doi.org/10.18632/oncotarget.8888

Xi Liu, Zhaoxia Li, Yue Song, Rui Wang, Lei Han, Qixue Wang, Kui Jiang, Chunsheng Kang,  and Qingyu Zhang
33152-33164
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Efficacy of adjuvant chemotherapy for non-small cell lung cancer assessed by metastatic potential associated with ACTN4

Efficacy of adjuvant chemotherapy for non-small cell lung cancer assessed by metastatic potential associated with ACTN4

https://doi.org/10.18632/oncotarget.8890

Nami Miura, Masahiro Kamita, Takanori Kakuya, Yutaka Fujiwara, Koji Tsuta, Hideaki Shiraishi, Fumitaka Takeshita, Takahiro Ochiya, Hirokazu Shoji, Wilber Huang, Yuichiro Ohe, Tesshi Yamada,  and Kazufumi Honda
33165-33178
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SSRI use and clinical outcomes in epithelial ovarian cancer

SSRI use and clinical outcomes in epithelial ovarian cancer

https://doi.org/10.18632/oncotarget.8891

Desiré K. Christensen, Guillermo N. Armaiz-Pena, Edgardo Ramirez, Koji Matsuo, Bridget Zimmerman, Behrouz Zand, Eileen Shinn, Michael J. Goodheart, David Bender, Premal H. Thaker, Amina Ahmed, Frank J. Penedo, Koen DeGeest, Luis Mendez, Frederick Domann, Anil K. Sood,  and Susan K. Lutgendorf
33179-33191
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting of glioblastoma cell lines and glioma stem cells by combined PIM kinase and PI3K-p110α inhibition

Targeting of glioblastoma cell lines and glioma stem cells by combined PIM kinase and PI3K-p110α inhibition

https://doi.org/10.18632/oncotarget.8899

Asneha Iqbal, Frank Eckerdt, Jonathan Bell, Ichiro Nakano, Francis J. Giles, Shi-Yuan Cheng, Rishi R. Lulla, Stewart Goldman,  and Leonidas C. Platanias
33192-33201
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Immunomodulatory role of bitter melon extract in inhibition of head and neck squamous cell carcinoma growth

Immunomodulatory role of bitter melon extract in inhibition of head and neck squamous cell carcinoma growth

https://doi.org/10.18632/oncotarget.8898

Sourav Bhattacharya, Naoshad Muhammad, Robert Steele, Guangyong Peng,  and Ratna B. Ray
33202-33209
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inflammatory indexes as predictors of prognosis and bevacizumab efficacy in patients with metastatic colorectal cancer

Inflammatory indexes as predictors of prognosis and bevacizumab efficacy in patients with metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.8901

Alessandro Passardi, Emanuela Scarpi, Luigi Cavanna, Monia Dall’Agata, Davide Tassinari, Silvana Leo, Ilaria Bernardini, Fabio Gelsomino, Stefano Tamberi, Alba A. Brandes, Elena Tenti, Roberto Vespignani, Giovanni L. Frassineti, Dino Amadori,  and Ugo De Giorgi
33210-33219
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Botulinum neurotoxin type C protease induces apoptosis in differentiated human neuroblastoma cells

Botulinum neurotoxin type C protease induces apoptosis in differentiated human neuroblastoma cells

https://doi.org/10.18632/oncotarget.8903

Aleksander Rust, Charlotte Leese, Thomas Binz,  and Bazbek Davletov
33220-33228
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long-term outcomes of imatinib in patients with FIP1L1/ PDGFRA associated chronic eosinophilic leukemia: experience of a single center in China

Long-term outcomes of imatinib in patients with FIP1L1/ PDGFRA associated chronic eosinophilic leukemia: experience of a single center in China

https://doi.org/10.18632/oncotarget.8906

Shi-Qiang Qu, Tie-Jun Qin, Ze-Feng Xu, Yue Zhang, Xiao-Fei Ai, Bing Li, Hong-Li Zhang, Li-Wei Fang, Li-Juan Pan, Nai-Bo Hu,  and Zhi-Jian Xiao
33229-33236
Abstract  |  PDF  |  HTML  |  Order a Reprint

In vivo screening and discovery of novel candidate thalidomide analogs in the zebrafish embryo and chicken embryo model systems

In vivo screening and discovery of novel candidate thalidomide analogs in the zebrafish embryo and chicken embryo model systems

https://doi.org/10.18632/oncotarget.8909

Shaunna L. Beedie, Holly M. Rore, Shelby Barnett, Cindy H. Chau, Weiming Luo, Nigel H. Greig, William D. Figg,  and Neil Vargesson
33237-33245
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Folate deficient tumor microenvironment promotes epithelial-to-mesenchymal transition and cancer stem-like phenotypes

Folate deficient tumor microenvironment promotes epithelial-to-mesenchymal transition and cancer stem-like phenotypes

https://doi.org/10.18632/oncotarget.8910

Yen-Hao Su, Wen-Chien Huang, Tse-Hung Huang, Yan-Jiun Huang, Yu-Kai Sue, Thanh-Tuan Huynh, Michael Hsiao, Tsan-Zon Liu, Alexander TH Wu,  and Chien-Min Lin
33246-33256
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

c-MYC inhibition impairs hypoxia response in glioblastoma multiforme

c-MYC inhibition impairs hypoxia response in glioblastoma multiforme

https://doi.org/10.18632/oncotarget.8921

Maria Patrizia Mongiardi, Mauro Savino, Maria Laura Falchetti, Barbara Illi, Francesca Bozzo, Cristiana Valle, Manuela Helmer-Citterich, Fabrizio Ferrè, Sergio Nasi,  and Andrea Levi
33257-33271
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The pro-apoptotic paradox: the BH3-only protein Bcl-2 interacting killer (Bik) is prognostic for unfavorable outcomes in breast cancer

The pro-apoptotic paradox: the BH3-only protein Bcl-2 interacting killer (Bik) is prognostic for unfavorable outcomes in breast cancer

https://doi.org/10.18632/oncotarget.8924

Vrajesh Pandya, Darryl Glubrecht, Larissa Vos, John Hanson, Sambasivarao Damaraju, John Mackey, Judith Hugh,  and Ing Swie Goping
33272-33285
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-17-5p regulates cell proliferation and migration by targeting transforming growth factor-β receptor 2 in gastric cancer

MiR-17-5p regulates cell proliferation and migration by targeting transforming growth factor-β receptor 2 in gastric cancer

https://doi.org/10.18632/oncotarget.8946

Yanjun Qu, Haiyang Zhang, Jingjing Duan, Rui Liu, Ting Deng, Ming Bai, Dingzhi Huang, Hongli Li, Tao Ning, Le Zhang, Xia Wang, Shaohua Ge, Likun Zhou, Benfu Zhong, Guoguang Ying,  and Yi Ba
33286-33296
Abstract  |  PDF  |  HTML  |  Order a Reprint

Spheroid cancer stem cells display reprogrammed metabolism and obtain energy by actively running the tricarboxylic acid (TCA) cycle

Spheroid cancer stem cells display reprogrammed metabolism and obtain energy by actively running the tricarboxylic acid (TCA) cycle

https://doi.org/10.18632/oncotarget.8947

Masakazu Sato, Kei Kawana, Katsuyuki Adachi, Asaha Fujimoto, Mitsuyo Yoshida, Hiroe Nakamura, Haruka Nishida, Tomoko Inoue, Ayumi Taguchi, Juri Takahashi, Satoko Eguchi, Aki Yamashita, Kensuke Tomio, Osamu Wada-Hiraike, Katsutoshi Oda, Takeshi Nagamatsu, Yutaka Osuga,  and Tomoyuki Fujii
33297-33305
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Effective treatment of ductal carcinoma in situ with a HER-2- targeted alpha-particle emitting radionuclide in a preclinical model of human breast cancer

Effective treatment of ductal carcinoma in situ with a HER-2- targeted alpha-particle emitting radionuclide in a preclinical model of human breast cancer

https://doi.org/10.18632/oncotarget.8949

Takahiro Yoshida, Kideok Jin, Hong Song, Sunju Park, David L. Huso, Zhe Zhang, Han Liangfeng, Charles Zhu, Frank Bruchertseifer, Alfred Morgenstern, George Sgouros,  and Saraswati Sukumar
33306-33315
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oncogenic ALK regulates EMT in non-small cell lung carcinoma through repression of the epithelial splicing regulatory protein 1

Oncogenic ALK regulates EMT in non-small cell lung carcinoma through repression of the epithelial splicing regulatory protein 1

https://doi.org/10.18632/oncotarget.8955

Claudia Voena, Lydia M. Varesio, Liye Zhang, Matteo Menotti, Teresa Poggio, Elena Panizza, Qi Wang, Valerio G. Minero, Sharmila Fagoonee, Mara Compagno, Fiorella Altruda, Stefano Monti,  and Roberto Chiarle
33316-33330
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Thalidomide enhanced the efficacy of CHOP chemotherapy in the treatment of diffuse large B cell lymphoma: A phase II study

Thalidomide enhanced the efficacy of CHOP chemotherapy in the treatment of diffuse large B cell lymphoma: A phase II study

https://doi.org/10.18632/oncotarget.8973

Dongmei Ji, Qiu Li, Junning Cao, Ye Guo, Fangfang Lv, Xiaojian Liu, Biyun Wang, Leiping Wang, Zhiguo Luo, Jianhua Chang, Xianghua Wu,  and Xiaonan Hong
33331-33339
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The platelet derived growth factor-B polymorphism is associated with risk of severe fever with thrombocytopenia syndrome in Chinese individuals

The platelet derived growth factor-B polymorphism is associated with risk of severe fever with thrombocytopenia syndrome in Chinese individuals

https://doi.org/10.18632/oncotarget.9043

Xiao-Ai Zhang, Chen-Tao Guo, Qing-Bin Lu, Jian-Gong Hu, Ning Cui, Zhen- Dong Yang, Wei Peng, Rong Liu, Chun-Yan Hu, Shu-Li Qin, Xian-Jun Wang, Shu-Jun Ding, Dou-Dou Huang, Wei Liu,  and Wu-Chun Cao
33340-33349
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Co-expression of PD-L1 and p-AKT is associated with poor prognosis in diffuse large B-cell lymphoma via PD-1/PD-L1 axis activating intracellular AKT/mTOR pathway in tumor cells

Co-expression of PD-L1 and p-AKT is associated with poor prognosis in diffuse large B-cell lymphoma via PD-1/PD-L1 axis activating intracellular AKT/mTOR pathway in tumor cells

https://doi.org/10.18632/oncotarget.9061

Ling Dong, Huijuan Lv, Wei Li, Zheng Song, Lanfang Li, Shiyong Zhou, Lihua Qiu, Zhengzi Qian, Xianming Liu, Lixia Feng, Bin Meng, Kai Fu, Xi Wang, Qiang Pan-Hammarström, Ping Wang, Xianhuo Wang,  and Huilai Zhang
33350-33362
Abstract  |  PDF  |  HTML  |  Order a Reprint

Kaposi’s sarcoma herpesvirus (KSHV) microRNA K12-1 functions as an oncogene by activating NF-κB/IL-6/STAT3 signaling

Kaposi’s sarcoma herpesvirus (KSHV) microRNA K12-1 functions as an oncogene by activating NF-κB/IL-6/STAT3 signaling

https://doi.org/10.18632/oncotarget.9221

Mingqing Chen, Fan Sun, Lei Han,  and Zhaoxia Qu
33363-33373
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Clinical predictive factors of pathologic complete response in locally advanced rectal cancer

Clinical predictive factors of pathologic complete response in locally advanced rectal cancer

https://doi.org/10.18632/oncotarget.8133

Francesca De Felice, Luciano Izzo, Daniela Musio, Anna Lisa Magnante, Nadia Bulzonetti, Federico Pugliese, Paolo Izzo, Pierfrancesco Di Cello, Pietro Lucchetti, Sara Izzo,  and Vincenzo Tombolini
33374-33380
Abstract  |  PDF  |  HTML  |  Order a Reprint

Risk of recurrence and conditional survival in complete responders treated with TKIs plus or less locoregional therapies for metastatic renal cell carcinoma

Risk of recurrence and conditional survival in complete responders treated with TKIs plus or less locoregional therapies for metastatic renal cell carcinoma

https://doi.org/10.18632/oncotarget.8302

Daniele Santini, Matteo Santoni, Alessandro Conti, Giuseppe Procopio, Elena Verzoni, Luca Galli, Giuseppe di Lorenzo, Ugo De Giorgi, Delia De Lisi, Maurizio Nicodemo, Marco Maruzzo, Francesco Massari, Sebastiano Buti, Emanuela Altobelli, Elisa Biasco, Riccardo Ricotta, Camillo Porta, Bruno Vincenzi, Rocco Papalia, Paolo Marchetti, Luciano Burattini, Rossana Berardi, Giovanni Muto, Rodolfo Montironi, Stefano Cascinu,  and Giuseppe Tonini
33381-33390
Abstract  |  PDF  |  HTML  |  Order a Reprint

Treatment outcome of nimotuzumab plus chemotherapy in advanced cancer patients: a single institute experience

Treatment outcome of nimotuzumab plus chemotherapy in advanced cancer patients: a single institute experience

https://doi.org/10.18632/oncotarget.8516

Shuping Xu, Mayra Ramos-Suzarte, Xianhong Bai,  and Binghe Xu
33391-33407
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Effect of intensity-modulated radiotherapy versus two-dimensional conventional radiotherapy alone in nasopharyngeal carcinoma

Effect of intensity-modulated radiotherapy versus two-dimensional conventional radiotherapy alone in nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.8573

Pu-Yun OuYang, Dingbo Shi, Rui Sun, Yu-Jia Zhu, Yao Xiao, Lu-Ning Zhang, Xu-Hui Zhang, Ze-Ying Chen, Xiao-Wen Lan, Jie Tang, Yuan-Hong Gao, Jun Ma, Wuguo Deng,  and Fang-Yun Xie
33408-33417
Abstract  |  PDF  |  HTML  |  Order a Reprint

Meta-analysis comparing maintenance strategies with continuous therapy and complete chemotherapy-free interval strategies in the treatment of metastatic colorectal cancer

Meta-analysis comparing maintenance strategies with continuous therapy and complete chemotherapy-free interval strategies in the treatment of metastatic colorectal cancer

https://doi.org/10.18632/oncotarget.8644

Lei Zhao, Jing Wang, Huihui Li, Juanjuan Che,  and Bangwei Cao
33418-33428
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reviews

Lipidome in colorectal cancer

Lipidome in colorectal cancer

https://doi.org/10.18632/oncotarget.7960

Guifang Yan, Liqi Li, Bo Zhu,  and Yongsheng Li
33429-33439
Abstract  |  PDF  |  HTML  |  Order a Reprint

PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma

PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma

https://doi.org/10.18632/oncotarget.7961

Xiaoman Li, Changjing Wu, Nianci Chen, Huadi Gu, Allen Yen, Liu Cao, Enhua Wang,  and Liang Wang
33440-33450
Abstract  |  PDF  |  HTML  |  Order a Reprint

Long-range and short-range tumor-stroma networks synergistically contribute to tumor-associated epilepsy

Long-range and short-range tumor-stroma networks synergistically contribute to tumor-associated epilepsy

https://doi.org/10.18632/oncotarget.7962

Xiao-Yuan Mao, Tursonjan Tokay, Hong-Hao Zhou,  and Wei-Lin Jin
33451-33460
Abstract  |  PDF  |  HTML  |  Order a Reprint

Brain tumor modeling using the CRISPR/Cas9 system: state of the art and view to the future

Brain tumor modeling using the CRISPR/Cas9 system: state of the art and view to the future

https://doi.org/10.18632/oncotarget.8075

Xiao-Yuan Mao, Jin-Xiang Dai, Hong-Hao Zhou, Zhao-Qian Liu,  and Wei-Lin Jin
33461-33471
Abstract  |  PDF  |  HTML  |  Order a Reprint

The application of the fibroblast activation protein α-targeted immunotherapy strategy

The application of the fibroblast activation protein α-targeted immunotherapy strategy

https://doi.org/10.18632/oncotarget.8098

Guan-Min Jiang, Wei Xu, Jun Du, Kun-Shui Zhang, Qiu-Gui Zhang, Xiao-Wei Wang, Zhi-Gang Liu, Shuang-Quan Liu, Wan-Ying Xie, Hui-Fang Liu, Jing-Shi Liu,  and Bai-Ping Wu
33472-33482
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Corrections

Correction: Insulin-like growth factor-independent insulin-like growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin β1

Correction: Insulin-like growth factor-independent insulin-like growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin β1

https://doi.org/10.18632/oncotarget.9711

Yi-Chen Yen, Jenn-Ren Hsiao, Shih Sheng Jiang, Jeffrey S. Chang, Ssu-Han Wang, Ying-Ying Shen, Chung-Hsing Chen, I-Shou Chang, Jang-Yang Chang,  and Ya-Wen Chen
33483
Correction  |  PDF


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