Oncotarget

Vol 7, No 19

May 10, 2016

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BIM mediates oncogene inactivation-induced apoptosis in multiple transgenic mouse models of acute lymphoblastic leukemia. See Li et al.

Table of Contents

Priority Research Papers

BIM mediates oncogene inactivation-induced apoptosis in multiple transgenic mouse models of acute lymphoblastic leukemia

BIM mediates oncogene inactivation-induced apoptosis in multiple transgenic mouse models of acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.8731

Yulin Li, Anja Deutzmann, Peter S. Choi, Alice C. Fan,  and Dean W. Felsher
26926-26934
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Research Papers: Gerotarget (Focus on Aging)

Gadd45b deficiency promotes premature senescence and skin aging

Gadd45b deficiency promotes premature senescence and skin aging

https://doi.org/10.18632/oncotarget.8854

Andrew Magimaidas, Priyanka Madireddi, Silvia Maifrede, Kaushiki Mukherjee, Barbara Hoffman,  and Dan A. Liebermann
26935-26948
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The anti-aging effects of LW-AFC via correcting immune dysfunctions in senescence accelerated mouse resistant 1 (SAMR1) strain

The anti-aging effects of LW-AFC via correcting immune dysfunctions in senescence accelerated mouse resistant 1 (SAMR1) strain

https://doi.org/10.18632/oncotarget.8877

Jianhui Wang, Xiaorui Cheng, Xiaorui Zhang, Junping Cheng, Yiran Xu, Ju Zeng, Wenxia Zhou,  and Yongxiang Zhang
26949-26965
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Glucocorticoid impairs cell-cell communication by autophagy-mediated degradation of connexin 43 in osteocytes

Glucocorticoid impairs cell-cell communication by autophagy-mediated degradation of connexin 43 in osteocytes

https://doi.org/10.18632/oncotarget.9034

Junjie Gao, Tak Sum Cheng, An Qin, Nathan J. Pavlos, Tao Wang, Kai Song, Yan Wang, Lianzhi Chen, Lin Zhou, Qing Jiang, Hiroshi Takayanagi, Sheng Yan,  and Minghao Zheng
26966-26978
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Research Papers: Pathology

Characterization of cytoplasmic cyclin D1 as a marker of invasiveness in cancer

Characterization of cytoplasmic cyclin D1 as a marker of invasiveness in cancer

https://doi.org/10.18632/oncotarget.8876

Noel P. Fusté, Esmeralda Castelblanco, Isidre Felip, Maria Santacana, Rita Fernández-Hernández, Sònia Gatius, Neus Pedraza, Judit Pallarés, Tània Cemeli, Joan Valls, Marc Tarres, Francisco Ferrezuelo, Xavier Dolcet, Xavier Matias-Guiu,  and Eloi Garí
26979-26991
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Research Papers: Immunology

Dysregulation of peritoneal cavity B1a cells and murine primary biliary cholangitis

Dysregulation of peritoneal cavity B1a cells and murine primary biliary cholangitis

https://doi.org/10.18632/oncotarget.8853

Yan-Qing Yang, Wei Yang, Yuan Yao, Hong-Di Ma, Yin-Hu Wang, Liang Li, Qingfa Wu, M. Eric Gershwin,  and Zhe-Xiong Lian
26992-27006
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ANXA1 inhibits miRNA-196a in a negative feedback loop through NF-kB and c-Myc to reduce breast cancer proliferation

ANXA1 inhibits miRNA-196a in a negative feedback loop through NF-kB and c-Myc to reduce breast cancer proliferation

https://doi.org/10.18632/oncotarget.8875

Yi Yuan, Durkeshwari Anbalagan, Lay Hoon Lee, Ramar Perumal Samy, Muthu K. Shanmugam, Alan Prem Kumar, Gautam Sethi, Peter E. Lobie,  and Lina H.K. Lim
27007-27020
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Research Papers

The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo

The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo

https://doi.org/10.18632/oncotarget.8395

Masashi Okada, Kenta Kuramoto, Hiroyuki Takeda, Hikaru Watarai, Hirotsugu Sakaki, Shizuka Seino, Manabu Seino, Shuhei Suzuki,  and Chifumi Kitanaka
27021-27032
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Colorectal cancer cell-derived extracellular vesicles induce phenotypic alteration of T cells into tumor-growth supporting cells with transforming growth factor-β1-mediated suppression

Colorectal cancer cell-derived extracellular vesicles induce phenotypic alteration of T cells into tumor-growth supporting cells with transforming growth factor-β1-mediated suppression

https://doi.org/10.18632/oncotarget.7041

Nami Yamada, Yuki Kuranaga, Minami Kumazaki, Haruka Shinohara, Kohei Taniguchi,  and Yukihiro Akao
27033-27043
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Efficacy and safety of sorafenib versus sunitinib as first-line treatment in patients with metastatic renal cell carcinoma: largest single-center retrospective analysis

Efficacy and safety of sorafenib versus sunitinib as first-line treatment in patients with metastatic renal cell carcinoma: largest single-center retrospective analysis

https://doi.org/10.18632/oncotarget.7395

Xinan Sheng, Zhihong Chi, Chuanliang Cui, Lu Si, Siming Li, Bixia Tang, Lili Mao, Bin Lian, Xuan Wang, Xieqiao Yan,  and Jun Guo
27044-27054
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mTOR inhibitors, a new era for metastatic luminal HER2-negative breast cancer? A systematic review and a meta-analysis of randomized trials

mTOR inhibitors, a new era for metastatic luminal HER2-negative breast cancer? A systematic review and a meta-analysis of randomized trials

https://doi.org/10.18632/oncotarget.7446

Maria Saveria Rotundo, Teresa Galeano, Pierfrancesco Tassone,  and Pierosandro Tagliaferri
27055-27066
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Stability of the hybrid epithelial/mesenchymal phenotype

Stability of the hybrid epithelial/mesenchymal phenotype

https://doi.org/10.18632/oncotarget.8166

Mohit Kumar Jolly, Satyendra C. Tripathi, Dongya Jia, Steven M. Mooney, Muge Celiktas, Samir M. Hanash, Sendurai A. Mani, Kenneth J. Pienta, Eshel Ben-Jacob,  and Herbert Levine
27067-27084
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The angiogenesis in decellularized scaffold-mediated the renal regeneration

The angiogenesis in decellularized scaffold-mediated the renal regeneration

https://doi.org/10.18632/oncotarget.7785

Jin Mei, Yaling Yu, Miaozhong Li, Shanshan Xi, Sixiao Zhang, Xiaolin Liu, Junqun Jiang, Zhibin Wang, Jianse Zhang, Yuqiang Ding, Xinfa Lou,  and Maolin Tang
27085-27093
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Novel signaling collaboration between TGF-β and adaptor protein Crk facilitates EMT in human lung cancer

Novel signaling collaboration between TGF-β and adaptor protein Crk facilitates EMT in human lung cancer

https://doi.org/10.18632/oncotarget.8314

Aiman Z. Elmansuri, Mishie A. Tanino, Roshan Mahabir, Lei Wang, Taichi Kimura, Hiroshi Nishihara, Ichiro Kinoshita, Hirotoshi Dosaka-Akita, Masumi Tsuda,  and Shinya Tanaka
27094-27107
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cyclin-dependent kinase 5 stabilizes hypoxia-inducible factor-1α: a novel approach for inhibiting angiogenesis in hepatocellular carcinoma

Cyclin-dependent kinase 5 stabilizes hypoxia-inducible factor-1α: a novel approach for inhibiting angiogenesis in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.8342

Julia Herzog, Sandra M. Ehrlich, Lisa Pfitzer, Johanna Liebl, Thomas Fröhlich, Georg J. Arnold, Wolfgang Mikulits, Christine Haider, Angelika M. Vollmar,  and Stefan Zahler
27108-27121
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mitophagy in TGEV infection counteracts oxidative stress and apoptosis

Mitophagy in TGEV infection counteracts oxidative stress and apoptosis

https://doi.org/10.18632/oncotarget.8345

Liqi Zhu, Chunxiao Mou, Xing Yang, Jian Lin,  and Qian Yang
27122-27141
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The platelet isoform of phosphofructokinase contributes to metabolic reprogramming and maintains cell proliferation in clear cell renal cell carcinoma

The platelet isoform of phosphofructokinase contributes to metabolic reprogramming and maintains cell proliferation in clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.8382

Jun Wang, Ping Zhang, Jie Zhong, Mingyue Tan, Jifu Ge, Le Tao, Yakui Li, Yemin Zhu, Lifang Wu, Jianxin Qiu,  and Xuemei Tong
27142-27157
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting the chromatin remodeling enzyme BRG1 increases the efficacy of chemotherapy drugs in breast cancer cells

Targeting the chromatin remodeling enzyme BRG1 increases the efficacy of chemotherapy drugs in breast cancer cells

https://doi.org/10.18632/oncotarget.8384

Qiong Wu, Soni Sharma, Hang Cui, Scott E. LeBlanc, Hong Zhang, Rohini Muthuswami, Jeffrey A. Nickerson,  and Anthony N. Imbalzano
27158-27175
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Loss of PIG3 increases HIF-1α level by promoting protein synthesis via mTOR pathway in renal cell carcinoma cells

Loss of PIG3 increases HIF-1α level by promoting protein synthesis via mTOR pathway in renal cell carcinoma cells

https://doi.org/10.18632/oncotarget.8401

Guang Chen, Jin-Ye Xu, Jie Chen, Jian-Xin Zhang, Jun Zhou, Yong Liang,  and Xiao-Fei Ding
27176-27184
Abstract  |  PDF  |  HTML  |  Order a Reprint

The degree of intratumor mutational heterogeneity varies by primary tumor sub-site

The degree of intratumor mutational heterogeneity varies by primary tumor sub-site

https://doi.org/10.18632/oncotarget.8448

Levi G. Ledgerwood, Dhruv Kumar, Agda Karina Eterovic, Jo Wick, Ken Chen, Hao Zhao, Loubna Tazi, Pradip Manna, Spencer Kerley, Radhika Joshi, Lin Wang, Simion I. Chiosea, James David Garnett, Terance Ted Tsue, Jeremy Chien, Gordon B. Mills, Jennifer Rubin Grandis,  and Sufi Mary Thomas
27185-27198
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pretreatment magnetic resonance imaging of regional lymph nodes with carcinoembryonic antigen in prediction of synchronous distant metastasis in patients with rectal cancer

Pretreatment magnetic resonance imaging of regional lymph nodes with carcinoembryonic antigen in prediction of synchronous distant metastasis in patients with rectal cancer

https://doi.org/10.18632/oncotarget.7979

Huanhuan Liu, Yanfen Cui, Wei Shen, Xingwen Fan, Long Cui, Caiyuan Zhang, Gang Ren, Jihong Fu,  and Dengbin Wang
27199-27207
Abstract  |  PDF  |  HTML  |  Order a Reprint

Comparative genomic analysis of primary tumors and metastases in breast cancer

Comparative genomic analysis of primary tumors and metastases in breast cancer

https://doi.org/10.18632/oncotarget.8349

François Bertucci, Pascal Finetti, Arnaud Guille, José Adélaïde, Séverine Garnier, Nadine Carbuccia, Audrey Monneur, Emmanuelle Charafe-Jauffret, Anthony Goncalves, Patrice Viens, Daniel Birnbaum,  and Max Chaffanet
27208-27219
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Molecular classification of cancer with the 92-gene assay in cytology and limited tissue samples

Molecular classification of cancer with the 92-gene assay in cytology and limited tissue samples

https://doi.org/10.18632/oncotarget.8449

Elena F. Brachtel, Theresa N. Operaña, Peggy S. Sullivan, Sarah E. Kerr, Karen A. Cherkis, Brock E. Schroeder, Sarah M. Dry,  and Catherine A. Schnabel
27220-27231
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circulating tumor cells exhibit stem cell characteristics in an orthotopic mouse model of colorectal cancer

Circulating tumor cells exhibit stem cell characteristics in an orthotopic mouse model of colorectal cancer

https://doi.org/10.18632/oncotarget.8373

Sebastian Schölch, Sebastián A. García, Naoki Iwata, Thomas Niemietz, Alexander M. Betzler, Lahiri K. Nanduri, Ulrich Bork, Christoph Kahlert, May-Linn Thepkaysone, Anka Swiersy, Markus W. Büchler, Christoph Reissfelder, Jürgen Weitz,  and Nuh N. Rahbari
27232-27242
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The feasibility of 18F-AlF-NOTA-PRGD2 PET/CT for monitoring early response of Endostar antiangiogenic therapy in human nasopharyngeal carcinoma xenograft model compared with 18F-FDG

The feasibility of 18F-AlF-NOTA-PRGD2 PET/CT for monitoring early response of Endostar antiangiogenic therapy in human nasopharyngeal carcinoma xenograft model compared with 18F-FDG

https://doi.org/10.18632/oncotarget.8402

Yanfen Cui, Huanhuan Liu, Sheng Liang, Caiyuan Zhang, Weiwei Cheng, Wangxi Hai, Bing Yin,  and Dengbin Wang
27243-27254
Abstract  |  PDF  |  HTML  |  Order a Reprint

High CD3+ and CD34+ peripheral blood stem cell grafts content is associated with increased risk of graft-versus-host disease without beneficial effect on disease control after reduced-intensity conditioning allogeneic transplantation from matched unrelated donors for acute myeloid leukemia — an analysis from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

High CD3+ and CD34+ peripheral blood stem cell grafts content is associated with increased risk of graft-versus-host disease without beneficial effect on disease control after reduced-intensity conditioning allogeneic transplantation from matched unrelated donors for acute myeloid leukemia — an analysis from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

https://doi.org/10.18632/oncotarget.8463

Tomasz Czerw, Myriam Labopin, Christoph Schmid, Jan J. Cornelissen, Patrice Chevallier, Didier Blaise, Jürgen Kuball, Stephane Vigouroux, Frédéric Garban, Bruno Lioure, Nathalie Fegueux, Laurence Clement, Anna Sandstedt, Johan Maertens, Gaëlle Guillerm, Dominique Bordessoule, Mohamad Mohty,  and Arnon Nagler
27255-27266
Abstract  |  PDF  |  HTML  |  Order a Reprint

Genistein mediates the selective radiosensitizing effect in NSCLC A549 cells via inhibiting methylation of the keap1 gene promoter region

Genistein mediates the selective radiosensitizing effect in NSCLC A549 cells via inhibiting methylation of the keap1 gene promoter region

https://doi.org/10.18632/oncotarget.8403

Xiongxiong Liu, Chao Sun, Bingtao Liu, Xiaodong Jin, Ping Li, Xiaogang Zheng, Ting Zhao, Feifei Li,  and Qiang Li
27267-27279
Abstract  |  PDF  |  HTML  |  Order a Reprint

LGR5 expression is controled by IKKα in basal cell carcinoma through activating STAT3 signaling pathway

LGR5 expression is controled by IKKα in basal cell carcinoma through activating STAT3 signaling pathway

https://doi.org/10.18632/oncotarget.8465

Jiantao Jia, Ying Shi, Bin Yan, Deshen Xiao, Weiwei Lai, Yu Pan, Yiqun Jiang, Ling Chen, Chao Mao, Jian Zhou, Sichuan Xi, Ya Cao, Shuang Liu,  and Yongguang Tao
27280-27294
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The phosphatase of regenerating liver-3 (PRL-3) is important for IL-6-mediated survival of myeloma cells

The phosphatase of regenerating liver-3 (PRL-3) is important for IL-6-mediated survival of myeloma cells

https://doi.org/10.18632/oncotarget.8422

Tobias S. Slørdahl, Pegah Abdollahi, Esten N. Vandsemb, Christoph Rampa, Kristine Misund, Katarzyna A. Baranowska, Marita Westhrin, Anders Waage, Torstein B. Rø,  and Magne Børset
27295-27306
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pre-diagnostic leukocyte mitochondrial DNA copy number and risk of lung cancer

Pre-diagnostic leukocyte mitochondrial DNA copy number and risk of lung cancer

https://doi.org/10.18632/oncotarget.8426

Shasha Meng, Immaculata De Vivo, Liming Liang, Zhibin Hu, David C. Christiani, Edward Giovannucci,  and Jiali Han
27307-27312
Abstract  |  PDF  |  HTML  |  Order a Reprint

Glucocorticoid receptor beta increases migration of human bladder cancer cells

Glucocorticoid receptor beta increases migration of human bladder cancer cells

https://doi.org/10.18632/oncotarget.8430

Lucien McBeth, Assumpta C. Nwaneri, Maria Grabnar, Jonathan Demeter, Andrea Nestor-Kalinoski,  and Terry D. Hinds, Jr.
27313-27324
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting estrogen/estrogen receptor alpha enhances Bacillus Calmette-Guérin efficacy in bladder cancer

Targeting estrogen/estrogen receptor alpha enhances Bacillus Calmette-Guérin efficacy in bladder cancer

https://doi.org/10.18632/oncotarget.8756

Zhiqun Shang, Yanjun Li, Iawen Hsu, Minghao Zhang, Jing Tian, Simeng Wen, Ruifa Han, Edward M. Messing, Chawnshang Chang, Yuanjie Niu,  and Shuyuan Yeh
27325-27335
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of autophagy potentiates anticancer property of 20(S)-ginsenoside Rh2 by promoting mitochondria-dependent apoptosis in human acute lymphoblastic leukaemia cells

Inhibition of autophagy potentiates anticancer property of 20(S)-ginsenoside Rh2 by promoting mitochondria-dependent apoptosis in human acute lymphoblastic leukaemia cells

https://doi.org/10.18632/oncotarget.8285

Ting Xia, Jiancheng Wang, Yingnan Wang, Yuanyuan Wang, Jianye Cai, Min Wang, Qidan Chen, Jia Song, Ziqi Yu, Wei Huang,  and Jianpei Fang
27336-27349
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Period2 downregulation inhibits glioma cell apoptosis by activating the MDM2-TP53 pathway

Period2 downregulation inhibits glioma cell apoptosis by activating the MDM2-TP53 pathway

https://doi.org/10.18632/oncotarget.8439

Niu Zhanfeng, Wang Chengquan, Xia Hechun, Wang Jun, Zhang Lijian, Ma Dede, Liu Wenbin,  and Yin Lei
27350-27362
Abstract  |  PDF  |  HTML  |  Order a Reprint

Systematic discovery of drug action mechanisms by an integrated chemical genomics approach: identification of functional disparities between azacytidine and decitabine

Systematic discovery of drug action mechanisms by an integrated chemical genomics approach: identification of functional disparities between azacytidine and decitabine

https://doi.org/10.18632/oncotarget.8455

Yao-Yu Hsieh, Tsui-Chin Huang, Hsiang-Ling Lo, Jyun-Yan Jhan, Shui-Tein Chen,  and Pei-Ming Yang
27363-27378
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Chronic arsenic trioxide exposure leads to enhanced aggressiveness via Met oncogene addiction in cancer cells

Chronic arsenic trioxide exposure leads to enhanced aggressiveness via Met oncogene addiction in cancer cells

https://doi.org/10.18632/oncotarget.8415

Kushtrim Kryeziu, Christine Pirker, Bernhard Englinger, Sushilla van Schoonhoven, Melanie Spitzwieser, Thomas Mohr, Wilfried Körner, Regina Weinmüllner, Koray Tav, Johannes Grillari, Margit Cichna-Markl, Walter Berger,  and Petra Heffeter
27379-27393
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Neuroendocrine-like cells -derived CXCL10 and CXCL11 induce the infiltration of tumor-associated macrophage leading to the poor prognosis of colorectal cancer

Neuroendocrine-like cells -derived CXCL10 and CXCL11 induce the infiltration of tumor-associated macrophage leading to the poor prognosis of colorectal cancer

https://doi.org/10.18632/oncotarget.8423

Yu-Jie Zeng, Wei Lai, Heng Wu, Lu Liu, He-Yang Xu, Jie Wang,  and Zhong-Hua Chu
27394-27407
Abstract  |  PDF  |  HTML  |  Order a Reprint

Apoptosis signal-regulating kinase 1 mediates the inhibitory effect of hepatocyte nuclear factor-4α on hepatocellular carcinoma

Apoptosis signal-regulating kinase 1 mediates the inhibitory effect of hepatocyte nuclear factor-4α on hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.8478

Cai-Feng Jiang, Liang-Zhi Wen, Chuan Yin, Wen-Ping Xu, Bin Shi, Xin Zhang,  and Wei-Fen Xie
27408-27421
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

p21-activated kinase 1 (PAK1) expression correlates with prognosis in solid tumors: A systematic review and meta-analysis

p21-activated kinase 1 (PAK1) expression correlates with prognosis in solid tumors: A systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.8320

Fang Fang, Jian Pan, Yi-Ping Li, Gang Li, Li-Xiao Xu, Guang-Hao Su, Zhi-Heng Li, Xing Feng,  and Jian Wang
27422-27429
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Human papillomavirus oncogenic E6 protein regulates human β-defensin 3 (hBD3) expression via the tumor suppressor protein p53

Human papillomavirus oncogenic E6 protein regulates human β-defensin 3 (hBD3) expression via the tumor suppressor protein p53

https://doi.org/10.18632/oncotarget.8443

Twishasri DasGupta, Emeka I. Nweze, Hong Yue, Liming Wang, Jessica Jin, Santosh K. Ghosh, Hameem I. Kawsar, Chad Zender, Elliot J. Androphy, Aaron Weinberg, Thomas S. McCormick,  and Ge Jin
27430-27444
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-31 functions as a tumor suppressor and increases sensitivity to mitomycin-C in urothelial bladder cancer by targeting integrin α5

MicroRNA-31 functions as a tumor suppressor and increases sensitivity to mitomycin-C in urothelial bladder cancer by targeting integrin α5

https://doi.org/10.18632/oncotarget.8479

Tianyuan Xu, Liang Qin, Zhaowei Zhu, Xianjin Wang, Yue Liu, Yong Fan, Shan Zhong, Xiaojing Wang, Xiaohua Zhang, Leilei Xia, Xiang Zhang, Chen Xu,  and Zhoujun Shen
27445-27457
Abstract  |  PDF  |  HTML  |  Order a Reprint

Post-treatment serum lactic dehydrogenase as a predictive indicator for distant metastasis and survival of patients with nasopharyngeal carcinoma

Post-treatment serum lactic dehydrogenase as a predictive indicator for distant metastasis and survival of patients with nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.8480

Jin Wang, Li Li, Bai-qiang Dong, Yu-jin Xu, Yuan-da Zheng, Zhong-wen Sun, Yang Yang, Yuan-Yuan Chen, Xiao-zhong Chen,  and Ming Chen
27458-27467
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Transcriptome-wide analysis of compression-induced microRNA expression alteration in breast cancer for mining therapeutic targets

Transcriptome-wide analysis of compression-induced microRNA expression alteration in breast cancer for mining therapeutic targets

https://doi.org/10.18632/oncotarget.8322

Baek Gil Kim, Suki Kang, Hyun Ho Han, Joo Hyun Lee, Ji Eun Kim, Sung Hwan Lee,  and Nam Hoon Cho
27468-27478
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Effect of IL-7 and IL-15 on T cell phenotype in myelodysplastic syndromes

Effect of IL-7 and IL-15 on T cell phenotype in myelodysplastic syndromes

https://doi.org/10.18632/oncotarget.8459

Wen Dong, Tingting Ding, Lei Wu, Xiubao Ren, P.K. Epling-Burnette,  and Lili Yang
27479-27488
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Inhibition of skeletal growth of human prostate cancer by the combination of docetaxel and BKM1644: an aminobisphosphonate derivative

Inhibition of skeletal growth of human prostate cancer by the combination of docetaxel and BKM1644: an aminobisphosphonate derivative

https://doi.org/10.18632/oncotarget.8481

Shumin Zhang, Lajos Gera, Kenza Mamouni, Xin Li, Zhengjia Chen, Omer Kucuk,  and Daqing Wu
27489-27498
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pyrosequencing quantified methylation level of BRCA1 promoter as prognostic factor for survival in breast cancer patient

Pyrosequencing quantified methylation level of BRCA1 promoter as prognostic factor for survival in breast cancer patient

https://doi.org/10.18632/oncotarget.8355

Feng-Feng Cai, Su Chen, Ming-Hong Wang, Xiao-Yan Lin, Lian Zhang, Jia-Xin Zhang, Lian-Xin Wang, Jun Yang, Jin-Hua Ding, Xin Pan, Zhi-Ming Shao,  and Ewelina Biskup
27499-27510
Abstract  |  PDF  |  HTML  |  Order a Reprint

Crosstalk between the IGF-1R/AKT/mTORC1 pathway and the tumor suppressors p53 and p27 determines cisplatin sensitivity and limits the effectiveness of an IGF-1R pathway inhibitor

Crosstalk between the IGF-1R/AKT/mTORC1 pathway and the tumor suppressors p53 and p27 determines cisplatin sensitivity and limits the effectiveness of an IGF-1R pathway inhibitor

https://doi.org/10.18632/oncotarget.8484

Batzaya Davaadelger, Lei Duan, Ricardo E. Perez, Steven Gitelis,  and Carl G. Maki
27511-27526
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Functional interplay between cylindromatosis and histone deacetylase 6 in ciliary homeostasis revealed by phenotypic analysis of double knockout mice

Functional interplay between cylindromatosis and histone deacetylase 6 in ciliary homeostasis revealed by phenotypic analysis of double knockout mice

https://doi.org/10.18632/oncotarget.8374

Jie Ran, Fan Yu, Juan Qin, Yijun Zhang, Yunfan Yang, Dengwen Li, Jun Zhou,  and Min Liu
27527-27537
Abstract  |  PDF  |  HTML  |  Order a Reprint

The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker

The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker

https://doi.org/10.18632/oncotarget.8485

Shuo Chen, Kai-Xuan Sun, Bo-Liang Liu, Zhi-Hong Zong,  and Yang Zhao
27538-27551
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Migration-inducing gene 7 promotes tumorigenesis and angiogenesis and independently predicts poor prognosis of epithelial ovarian cancer

Migration-inducing gene 7 promotes tumorigenesis and angiogenesis and independently predicts poor prognosis of epithelial ovarian cancer

https://doi.org/10.18632/oncotarget.8487

Bihui Huang, Mingzhu Yin, Xia Li, Guosheng Cao, Jin Qi, Ge Lou, Shijie Sheng, Junping Kou, Kang Chen,  and Boyang Yu
27552-27566
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RSK-mediated down-regulation of PDCD4 is required for proliferation, survival, and migration in a model of triple-negative breast cancer

RSK-mediated down-regulation of PDCD4 is required for proliferation, survival, and migration in a model of triple-negative breast cancer

https://doi.org/10.18632/oncotarget.8375

Rafael Cuesta,  and Marina K. Holz
27567-27583
Abstract  |  PDF  |  HTML  |  Order a Reprint

Lung cancer-derived galectin-1 contributes to cancer associated fibroblast-mediated cancer progression and immune suppression through TDO2/kynurenine axis

Lung cancer-derived galectin-1 contributes to cancer associated fibroblast-mediated cancer progression and immune suppression through TDO2/kynurenine axis

https://doi.org/10.18632/oncotarget.8488

Ya-Ling Hsu, Jen-Yu Hung, Shin-Yi Chiang, Shu-Fang Jian, Cheng-Ying Wu, Yi-Shiuan Lin, Ying-Ming Tsai, Shah-Hwa Chou, Ming-Ju Tsai,  and Po-Lin Kuo
27584-27598
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ATG9A loss confers resistance to trastuzumab via c-Cbl mediated Her2 degradation

ATG9A loss confers resistance to trastuzumab via c-Cbl mediated Her2 degradation

https://doi.org/10.18632/oncotarget.8504

Joao Nunes, Hua Zhang, Nicos Angelopoulos, Jyoti Chhetri, Clodia Osipo, Arnhild Grothey, Justin Stebbing,  and Georgios Giamas
27599-27612
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A double-negative feedback loop between E2F3b and miR- 200b regulates docetaxel chemosensitivity of human lung adenocarcinoma cells

A double-negative feedback loop between E2F3b and miR- 200b regulates docetaxel chemosensitivity of human lung adenocarcinoma cells

https://doi.org/10.18632/oncotarget.8376

Yanping Gao, Longbang Chen, Haizhu Song, Yitian Chen, Rui Wang,  and Bing Feng
27613-27626
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activation of epithelial proliferation induced by Eimeria acervulina infection in the duodenum may be associated with cholesterol metabolism

Activation of epithelial proliferation induced by Eimeria acervulina infection in the duodenum may be associated with cholesterol metabolism

https://doi.org/10.18632/oncotarget.8490

Lili Sun, Haibo Dong, Zhenchao Zhang, Jie Liu, Yun Hu, Yingdong Ni, Roland Grossmann,  and Ruqian Zhao
27627-27640
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Novel leptin OB3 peptide-induced signaling and progression in thyroid cancers: Comparison with leptin

Novel leptin OB3 peptide-induced signaling and progression in thyroid cancers: Comparison with leptin

https://doi.org/10.18632/oncotarget.8505

Yu-Chen SH Yang, Yu-Tang Chin, Meng-Ti Hsieh, Hsuan-Yu Lai, Chien-Chih Ke, Dana R. Crawford, Oscar K. Lee, Earl Fu, Shaker A. Mousa, Patricia Grasso, Leroy F. Liu, Heng-Yu Chang, Heng-Yuan Tang, Hung-Yun Lin,  and Paul J. Davis
27641-27654
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Improving molecular diagnosis of Chinese patients with Charcot-Marie-Tooth by targeted next-generation sequencing and functional analysis

Improving molecular diagnosis of Chinese patients with Charcot-Marie-Tooth by targeted next-generation sequencing and functional analysis

https://doi.org/10.18632/oncotarget.8377

Li-Xi Li, Shao-Yun Zhao, Zhi-Jun Liu, Wang Ni, Hong-Fu Li, Bao-Guo Xiao,  and Zhi-Ying Wu
27655-27664
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Single-nucleotide polymorphisms in PSCA and the risk of breast cancer in a Chinese population

Single-nucleotide polymorphisms in PSCA and the risk of breast cancer in a Chinese population

https://doi.org/10.18632/oncotarget.8491

Meng Wang, Xijing Wang, Sidney W. Fu, Xinghan Liu, Tianbo Jin, Huafeng Kang, Xiaobin Ma, Shuai Lin, Haitao Guan, Shuqun Zhang, Kang Liu, Cong Dai, Yuyao Zhu,  and Zhijun Dai
27665-27675
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Identification of granulocytic myeloid-derived suppressor cells (G-MDSCs) in the peripheral blood of Hodgkin and non-Hodgkin lymphoma patients

Identification of granulocytic myeloid-derived suppressor cells (G-MDSCs) in the peripheral blood of Hodgkin and non-Hodgkin lymphoma patients

https://doi.org/10.18632/oncotarget.8507

Olivia Marini, Cecilia Spina, Elda Mimiola, Adriana Cassaro, Giovanni Malerba, Giuseppe Todeschini, Omar Perbellini, Maria Scupoli, Giuseppe Carli, Davide Facchinelli, Marco Cassatella, Patrizia Scapini,  and Cristina Tecchio
27676-27688
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Lysine demethylase 2A promotes stemness and angiogenesis of breast cancer by upregulating Jagged1

Lysine demethylase 2A promotes stemness and angiogenesis of breast cancer by upregulating Jagged1

https://doi.org/10.18632/oncotarget.8381

Jing-Yi Chen, Chien-Feng Li, Pei-Yi Chu, You-Syuan Lai, Chung-Hsing Chen, Shih Sheng Jiang, Ming-Feng Hou,  and Wen-Chun Hung
27689-27710
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Repressor and activator protein accelerates hepatic ischemia reperfusion injury by promoting neutrophil inflammatory response

Repressor and activator protein accelerates hepatic ischemia reperfusion injury by promoting neutrophil inflammatory response

https://doi.org/10.18632/oncotarget.8509

Chang Xian Li, Chung Mau Lo, Qizhou Lian, Kevin Tak-Pan Ng, Xiao Bing Liu, Yuen Yuen Ma, Xiang Qi, Oscar Wai Ho Yeung, Vinay Tergaonkar, Xin Xiang Yang, Hui Liu, Jiang Liu, Yan Shao,  and Kwan Man
27711-27723
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Resistance of ground glass hepatocytes to oral antivirals in chronic hepatitis B patients and implication for the development of hepatocellular carcinoma

Resistance of ground glass hepatocytes to oral antivirals in chronic hepatitis B patients and implication for the development of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.8388

Hung-Wen Tsai, Yih-Jyh Lin, Han-Chieh Wu, Ting-Tsung Chang, I-Chin Wu, Pin-Nan Cheng, Chia-Jui Yen, Shih-Huang Chan, Wenya Huang,  and Ih-Jen Su
27724-27734
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The roles of tricellular tight junction protein lipolysis-stimulated lipoprotein receptor in malignancy of human endometrial cancer cells

The roles of tricellular tight junction protein lipolysis-stimulated lipoprotein receptor in malignancy of human endometrial cancer cells

https://doi.org/10.18632/oncotarget.8408

Hiroshi Shimada, Seiro Satohisa, Takayuki Kohno, Syunta Takahashi, Tsubasa Hatakeyama, Takumi Konno, Mitsuhiro Tsujiwaki, Tsuyoshi Saito,  and Takashi Kojima
27735-27752
Abstract  |  PDF  |  HTML  |  Order a Reprint

BCL2-BH4 antagonist BDA-366 suppresses human myeloma growth

BCL2-BH4 antagonist BDA-366 suppresses human myeloma growth

https://doi.org/10.18632/oncotarget.8513

Jiusheng Deng, Dongkyoo Park, Mengchang Wang, Ajay Nooka, Qiaoya Deng, Shannon Matulis, Jonathan Kaufman, Sagar Lonial, Lawrence H. Boise, Jacques Galipeau,  and Xingming Deng
27753-27763
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A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases

A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases

https://doi.org/10.18632/oncotarget.8526

Xilin Chen, Jianfeng Han, Jianhong Chu, Lingling Zhang, Jianying Zhang, Charlie Chen, Luxi Chen, Youwei Wang, Hongwei Wang, Long Yi, J. Bradley Elder, Qi-En Wang, Xiaoming He, Balveen Kaur, E. Antonio Chiocca,  and Jianhua Yu
27764-27777
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Downregulation of LncRNA GAS5 causes trastuzumab resistance in breast cancer

Downregulation of LncRNA GAS5 causes trastuzumab resistance in breast cancer

https://doi.org/10.18632/oncotarget.8413

Wentong Li, Limin Zhai, Hui Wang, Chuanliang Liu, Jinbao Zhang, Weijuan Chen,  and Qun Wei
27778-27786
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CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway

CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway

https://doi.org/10.18632/oncotarget.8497

Qiuyuan Wen, Weiyuan Wang, Jiadi Luo, Shuzhou Chu, Lingjiao Chen, Lina Xu, Hongjing Zang, Mohannad Ma Alnemah, Jian Ma,  and Songqing Fan
27787-27801
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies

Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies

https://doi.org/10.18632/oncotarget.8533

Muhammad Zaki Hidayatullah Fadlullah, Ivy Kim-Ni Chiang, Kalen R. Dionne, Pei San Yee, Chai Phei Gan, Kin Kit Sam, Kai Hung Tiong, Adrian Kwok Wen Ng, Daniel Martin, Kue Peng Lim, Thomas George Kallarakkal, Wan Mahadzir Wan Mustafa, Shin Hin Lau, Mannil Thomas Abraham, Rosnah Binti Zain, Zainal Ariff Abdul Rahman, Alfredo Molinolo, Vyomesh Patel, J. Silvio Gutkind, Aik Choon Tan,  and Sok Ching Cheong
27802-27818
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Icariside II, a natural mTOR inhibitor, disrupts aberrant energy homeostasis via suppressing mTORC1-4E-BP1 axis in sarcoma cells

Icariside II, a natural mTOR inhibitor, disrupts aberrant energy homeostasis via suppressing mTORC1-4E-BP1 axis in sarcoma cells

https://doi.org/10.18632/oncotarget.8538

Chao Zhang, Lei Yang, Ya-di Geng, Fa-liang An, Yuan-zheng Xia, Chao Guo, Jian-guang Luo, Lu-yong Zhang, Qing-long Guo,  and Ling-yi Kong
27819-27837
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Telomerase reverse transcriptase promoter mutations in hepatitis B virus-associated hepatocellular carcinoma

Telomerase reverse transcriptase promoter mutations in hepatitis B virus-associated hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.8539

Xunjun Yang, Xiuchan Guo, Yao Chen, Guorong Chen, Yin Ma, Kate Huang, Yuning Zhang, Qiongya Zhao, Cheryl A. Winkler, Ping An,  and Jianxin Lyu
27838-27847
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comparison of the RECIST and PERCIST criteria in solid tumors: a pooled analysis and review

Comparison of the RECIST and PERCIST criteria in solid tumors: a pooled analysis and review

https://doi.org/10.18632/oncotarget.8425

Seon Jeong Min, Hyun Joo Jang,  and Jung Han Kim
27848-27854
Abstract  |  PDF  |  HTML  |  Order a Reprint

Spatial memory impairment by TRPC1 depletion is ameliorated by environmental enrichment

Spatial memory impairment by TRPC1 depletion is ameliorated by environmental enrichment

https://doi.org/10.18632/oncotarget.8428

Renzhong Xing, Yanling Zhang, Hua Xu, Xiaobin Luo, Raymond Chuen-Chung Chang, Jianjun Liu,  and Xifei Yang
27855-27873
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REG4 promotes peritoneal metastasis of gastric cancer through GPR37

REG4 promotes peritoneal metastasis of gastric cancer through GPR37

https://doi.org/10.18632/oncotarget.8442

Hexiao Wang, Lei Hu, Mingde Zang, Baogui Zhang, Yantao Duan, Zhiyuan Fan, Jianfang Li, Liping Su, Min Yan, Zhenggang Zhu, Bingya Liu,  and Qiumeng Yang
27874-27888
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Read-through transcripts in normal human lung parenchyma are down-regulated in lung adenocarcinoma

Read-through transcripts in normal human lung parenchyma are down-regulated in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.8556

Giulia Pintarelli, Alice Dassano, Chiara E. Cotroneo, Antonella Galvan, Sara Noci, Rocco Piazza, Alessandra Pirola, Roberta Spinelli, Matteo Incarbone, Alessandro Palleschi, Lorenzo Rosso, Luigi Santambrogio, Tommaso A. Dragani,  and Francesca Colombo
27889-27898
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comprehensive analysis of genome-wide DNA methylation across human polycystic ovary syndrome ovary granulosa cell

Comprehensive analysis of genome-wide DNA methylation across human polycystic ovary syndrome ovary granulosa cell

https://doi.org/10.18632/oncotarget.8544

Jiawei Xu, Xiao Bao, Zhaofeng Peng, Linlin Wang, Linqing Du, Wenbin Niu,  and Yingpu Sun
27899-27909
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The etiology of Ebola virus disease-like illnesses in Ebola virusnegative patients from Sierra Leone

The etiology of Ebola virus disease-like illnesses in Ebola virusnegative patients from Sierra Leone

https://doi.org/10.18632/oncotarget.8558

Wen-Gang Li, Wei-Wei Chen, Lei Li, Dong Ji, Ying-Jie Ji, Chen Li, Xu-Dong Gao, Li-Fu Wang, Min Zhao, Xue-Zhang Duan,  and Hui-Juan Duan
27910-27915
Abstract  |  PDF  |  HTML  |  Order a Reprint

Behavioral alterations following blood-brain barrier disruption stimulated by focused ultrasound

Behavioral alterations following blood-brain barrier disruption stimulated by focused ultrasound

https://doi.org/10.18632/oncotarget.8444

Feng-Yi Yang, Sheng-Fang Huang,  and Irene Han-Juo Cheng
27916-27925
Abstract  |  PDF  |  HTML  |  Order a Reprint

Pseudotyped αvβ6 integrin-targeted adenovirus vectors for ovarian cancer therapies

Pseudotyped αvβ6 integrin-targeted adenovirus vectors for ovarian cancer therapies

https://doi.org/10.18632/oncotarget.8545

Hanni Uusi-Kerttula, James Davies, Lynda Coughlan, Sarah Hulin-Curtis, Rachel Jones, Louise Hanna, John D. Chester,  and Alan L. Parker
27926-27937
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Parecoxib prevents complications in hepatocellular carcinoma patients receiving hepatic transarterial chemoembolization: a prospective score-matched cohort study

Parecoxib prevents complications in hepatocellular carcinoma patients receiving hepatic transarterial chemoembolization: a prospective score-matched cohort study

https://doi.org/10.18632/oncotarget.8560

Zhong-Guo Zhou, Jin-Bin Chen, Hai-Bo Qiu, Ruo-Jing Wang, Jian-Cong Chen, Li Xu, Min-Shan Chen,  and Yao-Jun Zhang
27938-27945
Abstract  |  PDF  |  HTML  |  Order a Reprint

High efficacy of the BCL-2 inhibitor ABT199 (venetoclax) in BCL-2 high-expressing neuroblastoma cell lines and xenografts and rational for combination with MCL-1 inhibition

High efficacy of the BCL-2 inhibitor ABT199 (venetoclax) in BCL-2 high-expressing neuroblastoma cell lines and xenografts and rational for combination with MCL-1 inhibition

https://doi.org/10.18632/oncotarget.8547

Laurel T. Bate-Eya, Ilona J.M. den Hartog, Ida van der Ploeg, Linda Schild, Jan Koster, Evan E. Santo, Ellen M. Westerhout, Rogier Versteeg, Huib N. Caron, Jan J. Molenaar,  and M. Emmy M. Dolman
27946-27958
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

KDM1A promotes tumor cell invasion by silencing TIMP3 in non-small cell lung cancer cells

KDM1A promotes tumor cell invasion by silencing TIMP3 in non-small cell lung cancer cells

https://doi.org/10.18632/oncotarget.8563

Lingzhi Kong, Peng Zhang, Wang Li, Yan Yang, Ye Tian, Xujun Wang, Sujun Chen, Yuxin Yang, Tianhao Huang, Tian Zhao, Liang Tang, Bo Su, Fei Li, X. Shirley Liu,  and Fan Zhang
27959-27974
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Interaction of KLF6 and Sp1 regulates basigin-2 expression mediated proliferation, invasion and metastasis in hepatocellular carcinoma

Interaction of KLF6 and Sp1 regulates basigin-2 expression mediated proliferation, invasion and metastasis in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.8564

Ling-Min Kong, Li Yao, Ning Lu, Ya-Lu Dong, Jing Zhang, Yong-Qiang Wang, Lili Liu, He-Long Zhang, Jian-Guo Huang,  and Cheng-Gong Liao
27975-27987
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

eNOS polymorphisms and clinical outcome in advanced HCC patients receiving sorafenib: final results of the ePHAS study

eNOS polymorphisms and clinical outcome in advanced HCC patients receiving sorafenib: final results of the ePHAS study

https://doi.org/10.18632/oncotarget.8569

Andrea Casadei Gardini, Giorgia Marisi, Luca Faloppi, Emanuela Scarpi, Francesco Giuseppe Foschi, Massimo Iavarone, Gianfranco Lauletta, Jody Corbelli, Martina Valgiusti, Floriana Facchetti, Cristina della Corte, Luca Maria Neri, Stefano Tamberi, Stefano Cascinu, Mario Scartozzi, Dino Amadori, Oriana Nanni, Elena Tenti, Paola Ulivi,  and Giovanni Luca Frassineti
27988-27999
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-452 promotes stem-like cells of hepatocellular carcinoma by inhibiting Sox7 involving Wnt/β-catenin signaling pathway

MicroRNA-452 promotes stem-like cells of hepatocellular carcinoma by inhibiting Sox7 involving Wnt/β-catenin signaling pathway

https://doi.org/10.18632/oncotarget.8584

Zhiyun Zheng, Jimin Liu, Zhe Yang, Limin Wu, Haiyang Xie, Chaozhe Jiang, Binyi Lin, Tianchi Chen, Chunyang Xing, Zhikun Liu, Penghong Song, Shengyong Yin, Shusen Zheng,  and Lin Zhou
28000-28012
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hepatitis B virus X protein up-regulates C4b-binding protein α through activating transcription factor Sp1 in protection of hepatoma cells from complement attack

Hepatitis B virus X protein up-regulates C4b-binding protein α through activating transcription factor Sp1 in protection of hepatoma cells from complement attack

https://doi.org/10.18632/oncotarget.8472

Guoxing Feng, Jiong Li, Minying Zheng, Zhe Yang, Yunxia Liu, Shuqin Zhang, Lihong Ye, Weiying Zhang,  and Xiaodong Zhang
28013-28026
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Distinct epigenetic signatures elucidate enhancer-gene relationships that delineate CIMP and non-CIMP colorectal cancers

Distinct epigenetic signatures elucidate enhancer-gene relationships that delineate CIMP and non-CIMP colorectal cancers

https://doi.org/10.18632/oncotarget.8473

Allen Chong, Jing Xian Teo,  and Kenneth H.K. Ban
28027-28039
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Age-related effects of X-ray irradiation on mouse hippocampus

Age-related effects of X-ray irradiation on mouse hippocampus

https://doi.org/10.18632/oncotarget.8575

Arianna Casciati, Katalin Dobos, Francesca Antonelli, Anett Benedek, Stefan J. Kempf, Montserrat Bellés, Andrea Balogh, Mirella Tanori, Luis Heredia, Michael J. Atkinson, Christine von Toerne, Omid Azimzadeh, Anna Saran, Geza Sáfrány, Mohammed A. Benotmane, M. Victoria Linares-Vidal, Soile Tapio, Katalin Lumniczky,  and Simonetta Pazzaglia
28040-28058
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Immune-mediated liver injury of the cancer therapeutic antibody catumaxomab targeting EpCAM, CD3 and Fcγ receptors

Immune-mediated liver injury of the cancer therapeutic antibody catumaxomab targeting EpCAM, CD3 and Fcγ receptors

https://doi.org/10.18632/oncotarget.8574

Jürgen Borlak, Florian Länger, Reinhard Spanel, Georg Schöndorfer,  and Christian Dittrich
28059-28074
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumor-suppressive miR-218-5p inhibits cancer cell proliferation and migration via EGFR in non-small cell lung cancer

Tumor-suppressive miR-218-5p inhibits cancer cell proliferation and migration via EGFR in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.8576

Kegan Zhu, Hanying Ding, Wengong Wang, Zhicong Liao, Zheng Fu, Yeting Hong, Yong Zhou, Chen-Yu Zhang,  and Xi Chen
28075-28085
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic profile of GNAQ-mutated blue melanocytic neoplasms reveals mutations in genes linked to genomic instability and the PI3K pathway

Genetic profile of GNAQ-mutated blue melanocytic neoplasms reveals mutations in genes linked to genomic instability and the PI3K pathway

https://doi.org/10.18632/oncotarget.8578

Mileidys Pérez-Alea, Ana Vivancos, Ginevra Caratú, Judit Matito, Berta Ferrer, Javier Hernandez-Losa, Javier Cortés, Eva Muñoz, Vicente Garcia-Patos,  and Juan A. Recio
28086-28095
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Differential effects of lenalidomide during plasma cell differentiation

Differential effects of lenalidomide during plasma cell differentiation

https://doi.org/10.18632/oncotarget.8581

Michel Jourdan, Maïlys Cren, Peter Schafer, Nicolas Robert, Christophe Duperray, Laure Vincent, Patrice Ceballos, Guillaume Cartron, Jean-François Rossi, Jérôme Moreaux, Rajesh Chopra,  and Bernard Klein
28096-28111
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Associations of potentially functional variants in IL-6, JAKs and STAT3 with gastric cancer risk in an eastern Chinese population

Associations of potentially functional variants in IL-6, JAKs and STAT3 with gastric cancer risk in an eastern Chinese population

https://doi.org/10.18632/oncotarget.8492

Fei Zhou, Lei Cheng, Li-Xin Qiu, Meng-Yun Wang, Jin Li, Meng-Hong Sun, Ya-Jun Yang, Jiu-Cun Wang, Li Jin, Ya-Nong Wang,  and Qing-Yi Wei
28112-28123
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Evaluating the diagnostic and prognostic value of circulating cathepsin S in gastric cancer

Evaluating the diagnostic and prognostic value of circulating cathepsin S in gastric cancer

https://doi.org/10.18632/oncotarget.8582

Wan-Li Liu, Dan Liu, Kai Cheng, Yi-Jun Liu, Shan Xing, Pei-dong Chi, Xiao-Hua Liu, Ning Xue, Yan-zhen Lai, Ling Guo,  and Ge Zhang
28124-28138
Abstract  |  PDF  |  HTML  |  Order a Reprint

Changes in plasma chemokine C-C motif ligand 2 levels during treatment with eicosapentaenoic acid predict outcome in patients undergoing surgery for colorectal cancer liver metastasis

Changes in plasma chemokine C-C motif ligand 2 levels during treatment with eicosapentaenoic acid predict outcome in patients undergoing surgery for colorectal cancer liver metastasis

https://doi.org/10.18632/oncotarget.8579

Milene Volpato, Sarah L Perry, Gemma Marston, Nicola Ingram, Andrew J. Cockbain, Heather Burghel, Jake Mann, David Lowes, Erica Wilson, Alastair Droop, Juliette Randerson-Moor, P Louise Coletta,  and Mark A Hull
28139-28150
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Non-invasive assessment of inter-and intrapatient variability of integrin expression in metastasized prostate cancer by PET

Non-invasive assessment of inter-and intrapatient variability of integrin expression in metastasized prostate cancer by PET

https://doi.org/10.18632/oncotarget.8611

Ambros J. Beer, Sarah M. Schwarzenböck, Niko Zantl, Michael Souvatzoglou, Tobias Maurer, Petra Watzlowik, Horst Kessler, Hans-Jürgen Wester, Markus Schwaiger,  and Bernd Joachim Krause
28151-28159
Abstract  |  PDF  |  HTML  |  Order a Reprint

Gap junction-mediated transfer of miR-145-5p from microvascular endothelial cells to colon cancer cells inhibits angiogenesis

Gap junction-mediated transfer of miR-145-5p from microvascular endothelial cells to colon cancer cells inhibits angiogenesis

https://doi.org/10.18632/oncotarget.8583

Dominique Thuringer, Gaetan Jego, Kevin Berthenet, Arlette Hammann, Eric Solary,  and Carmen Garrido
28160-28168
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress

Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress

https://doi.org/10.18632/oncotarget.8612

Sekyung Oh, Ryan A. Flynn, Stephen N. Floor, James Purzner, Lance Martin, Brian T. Do, Simone Schubert, Dedeepya Vaka, Sorana Morrissy, Yisu Li, Marcel Kool, Volker Hovestadt, David T.W. Jones, Paul A. Northcott, Thomas Risch, Hans-Jörg Warnatz, Marie-Laure Yaspo, Christopher M. Adams, Ryan D. Leib, Marcus Breese, Marco A. Marra, David Malkin, Peter Lichter, Jennifer A. Doudna, Stefan M. Pfister, Michael D. Taylor, Howard Y. Chang,  and Yoon-Jae Cho
28169-28182
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hypoxia primes human normal prostate epithelial cells and cancer cell lines for the NLRP3 and AIM2 inflammasome activation

Hypoxia primes human normal prostate epithelial cells and cancer cell lines for the NLRP3 and AIM2 inflammasome activation

https://doi.org/10.18632/oncotarget.8594

Ravichandran Panchanathan, Hongzhu Liu,  and Divaker Choubey
28183-28194
Abstract  |  PDF  |  HTML  |  Order a Reprint

miRNA array screening reveals cooperative MGMT-regulation between miR-181d-5p and miR-409-3p in glioblastoma

miRNA array screening reveals cooperative MGMT-regulation between miR-181d-5p and miR-409-3p in glioblastoma

https://doi.org/10.18632/oncotarget.8618

Susanna Khalil, Enrica Fabbri, Alessandra Santangelo, Valentino Bezzerri, Cinzia Cantù, Gianfranco Di Gennaro, Alessia Finotti, Claudio Ghimenton, Albino Eccher, Maria Dechecchi, Aldo Scarpa, Brian Hirshman, Clark Chen, Manuela Ferracin, Massimo Negrini, Roberto Gambari,  and Giulio Cabrini
28195-28206
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sp1 and COX2 expression is positively correlated with a poor prognosis in pancreatic ductal adenocarcinoma

Sp1 and COX2 expression is positively correlated with a poor prognosis in pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.8593

Junjie Hang, Hai Hu, Junjie Huang, Ting Han, Meng Zhuo, Yangyang Zhou, Lei Wang, Yi Wang, Feng Jiao,  and Liwei Wang
28207-28217
Abstract  |  PDF  |  HTML  |  Order a Reprint

PEDF inhibits pancreatic tumorigenesis by attenuating the fibro-inflammatory reaction

PEDF inhibits pancreatic tumorigenesis by attenuating the fibro-inflammatory reaction

https://doi.org/10.18632/oncotarget.8587

Daniel R. Principe, Brian DeCant, Andrew M. Diaz, Riley J. Mangan, Rosa Hwang, Andrew Lowy, Brandon B. Shetuni, Bharath K. Sreekumar, Chuhan Chung, David J. Bentrem, Hidayatullah G. Munshi, Barbara Jung, Paul J. Grippo,  and Faraz Bishehsari
28218-28234
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metformin represses bladder cancer progression by inhibiting stem cell repopulation via COX2/PGE2/STAT3 axis

Metformin represses bladder cancer progression by inhibiting stem cell repopulation via COX2/PGE2/STAT3 axis

https://doi.org/10.18632/oncotarget.8595

Qiuli Liu, Wenqiang Yuan, Dali Tong, Gaolei Liu, Weihua Lan, Dianzheng Zhang, Hualiang Xiao, Yao Zhang, Zaoming Huang, Junjie Yang, Jun Zhang,  and Jun Jiang
28235-28246
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preclinical evaluation of the anti-tumor effects of the natural isoflavone genistein in two xenograft mouse models monitored by [18F]FDG, [18F]FLT, and [64Cu]NODAGA-cetuximab small animal PET

Preclinical evaluation of the anti-tumor effects of the natural isoflavone genistein in two xenograft mouse models monitored by [18F]FDG, [18F]FLT, and [64Cu]NODAGA-cetuximab small animal PET

https://doi.org/10.18632/oncotarget.8625

Valerie S. Honndorf, Stefan Wiehr, Anna-Maria Rolle, Julia Schmitt, Luisa Kreft, Letitia Quintanilla-Martinez, Ursula Kohlhofer, Gerald Reischl, Andreas Maurer, Karsten Boldt, Michael Schwarz, Holger Schmidt,  and Bernd J. Pichler
28247-28261
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gene therapy for colorectal cancer using adenovirus-mediated full-length antibody, cetuximab

Gene therapy for colorectal cancer using adenovirus-mediated full-length antibody, cetuximab

https://doi.org/10.18632/oncotarget.8596

Man Xing, Xiang Wang, Yudan Chi,  and Dongming Zhou
28262-28272
Abstract  |  PDF  |  HTML  |  Order a Reprint

The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance

The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance

https://doi.org/10.18632/oncotarget.8626

Kevin S. Quackenbush, Stacey Bagby, Wai Meng Tai, Wells A. Messersmith, Anna Schreiber, Justin Greene, Jihye Kim, Guoliang Wang, Alicia Purkey, Todd M. Pitts, Anna Nguyen, Dexiang Gao, Patrick Blatchford, Anna Capasso, Alwin G. Schuller, S. Gail Eckhardt,  and John J. Arcaroli
28273-28285
Abstract  |  PDF  |  HTML  |  Order a Reprint

Apoptotic transition of senescent cells accompanied with mitochondrial hyper-function

Apoptotic transition of senescent cells accompanied with mitochondrial hyper-function

https://doi.org/10.18632/oncotarget.8536

Danli Wang, Yang Liu, Rui Zhang, Fen Zhang, Weihao Sui, Li Chen, Ran Zheng, Xiaowen Chen, Feiqiu Wen, Hong-Wei Ouyang,  and Junfeng Ji
28286-28300
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A new role of the Rac-GAP β2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression

A new role of the Rac-GAP β2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression

https://doi.org/10.18632/oncotarget.8597

Victoria Casado-Medrano, Laura Barrio-Real, Ginesa García-Rostán, Matti Baumann, Oliver Rocks,  and María J. Caloca
28301-28319
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Down-regulation of LAPTM5 in human cancer cells

Down-regulation of LAPTM5 in human cancer cells

https://doi.org/10.18632/oncotarget.8614

Michelle Nuylan, Tatsuyuki Kawano, Johji Inazawa,  and Jun Inoue
28320-28328
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Histone deacetylase inhibitor-induced cancer stem cells exhibit high pentose phosphate pathway metabolism

Histone deacetylase inhibitor-induced cancer stem cells exhibit high pentose phosphate pathway metabolism

https://doi.org/10.18632/oncotarget.8631

Bisrat G. Debeb, Lara Lacerda, Richard Larson, Adam R. Wolfe, Savitri Krishnamurthy, James M. Reuben, Naoto T. Ueno, Michael Gilcrease,  and Wendy A. Woodward
28329-28339
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

c-Src activation promotes nasopharyngeal carcinoma metastasis by inducing the epithelial-mesenchymal transition via PI3K/Akt signaling pathway: a new and promising target for NPC

c-Src activation promotes nasopharyngeal carcinoma metastasis by inducing the epithelial-mesenchymal transition via PI3K/Akt signaling pathway: a new and promising target for NPC

https://doi.org/10.18632/oncotarget.8634

Liangru Ke, Yanqun Xiang, Xiang Guo, Jinping Lu, Weixiong Xia, Yahui Yu, Yongjian Peng, Li Wang, Gang Wang, Yanfang Ye, Jing Yang, Hu Liang, Tiebang Kang,  and Xing Lv
28340-28355
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mutation profiling in chinese patients with metastatic colorectal cancer and its correlation with clinicopathological features and anti-EGFR treatment response

Mutation profiling in chinese patients with metastatic colorectal cancer and its correlation with clinicopathological features and anti-EGFR treatment response

https://doi.org/10.18632/oncotarget.8541

Zhe-Zhen Li, Feng Wang, Zi-Chen Zhang, Fang Wang, Qi Zhao, Dong-Sheng Zhang, Feng-Hua Wang, Zhi-Qiang Wang, Hui-Yan Luo, Ming-Ming He, De-Shen Wang, Ying Jin, Chao Ren, Miao-Zhen Qiu, Jian Ren, Zhi-Zhong Pan, Yu-Hong Li, Jiao-Yong Shao,  and Rui-Hua Xu
28356-28368
Abstract  |  PDF  |  HTML  |  Order a Reprint

Selenium-enriched polysaccharides from Pyracantha fortuneana (Se-PFPs) inhibit the growth and invasive potential of ovarian cancer cells through inhibiting β-catenin signaling

Selenium-enriched polysaccharides from Pyracantha fortuneana (Se-PFPs) inhibit the growth and invasive potential of ovarian cancer cells through inhibiting β-catenin signaling

https://doi.org/10.18632/oncotarget.8619

Qianling Sun, Mengmeng Dong, Zhihui Wang, Changdong Wang, Deqiao Sheng, Zhihong Li, Debin Huang,  and Chengfu Yuan
28369-28383
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Low expression of protocadherin7 (PCDH7) is a potential prognostic biomarker for primary non-muscle invasive bladder cancer

Low expression of protocadherin7 (PCDH7) is a potential prognostic biomarker for primary non-muscle invasive bladder cancer

https://doi.org/10.18632/oncotarget.8635

Ying-Li Lin, Yan-Ling Wang, Xing-Li Fu, Wen-Ping Li, Yu-Hao Wang,  and Jian-Guo Ma
28384-28392
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dual oncogenic and tumor suppressor roles of the promyelocytic leukemia gene in hepatocarcinogenesis associated with hepatitis B virus surface antigen

Dual oncogenic and tumor suppressor roles of the promyelocytic leukemia gene in hepatocarcinogenesis associated with hepatitis B virus surface antigen

https://doi.org/10.18632/oncotarget.8613

Yih-Lin Chung,  and Mei-Ling Wu
28393-28407
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Radiotherapy dose led to a substantial prolongation of survival in patients with locally advanced rectosigmoid junction cancer: a large population based study

Radiotherapy dose led to a substantial prolongation of survival in patients with locally advanced rectosigmoid junction cancer: a large population based study

https://doi.org/10.18632/oncotarget.8630

Xu Guan, Zheng Jiang, Tianyi Ma, Zheng Liu, Hanqing Hu, Zhixun Zhao, Dawei Song, Yinggang Chen, Guiyu Wang,  and Xishan Wang
28408-28419
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-34a-5p promotes the multi-drug resistance of osteosarcoma by targeting the CD117 gene

MiR-34a-5p promotes the multi-drug resistance of osteosarcoma by targeting the CD117 gene

https://doi.org/10.18632/oncotarget.8546

Youguang Pu, Fangfang Zhao, Haiyan Wang, Wenjing Cai, Jin Gao, Yinpeng Li,  and Shanbao Cai
28420-28434
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

mTORC1-mediated downregulation of COX2 restrains tumor growth caused by TSC2 deficiency

mTORC1-mediated downregulation of COX2 restrains tumor growth caused by TSC2 deficiency

https://doi.org/10.18632/oncotarget.8633

Hongwu Li, Fuquan Jin, Keguo Jiang, Shuang Ji, Li Wang, Zhaofei Ni, Xianguo Chen, Zhongdong Hu, Hongbing Zhang, Yehai Liu, Yide Qin,  and Xiaojun Zha
28435-28447
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Protein profiling of alpha-fetoprotein producing gastric adenocarcinoma

Protein profiling of alpha-fetoprotein producing gastric adenocarcinoma

https://doi.org/10.18632/oncotarget.8571

Liang He, Fei Ye, Linlin Qu, Daguang Wang, Miao Cui, Chengguo Wei, Yanpeng Xing, Peng Lee, Jian Suo,  and David Y. Zhang
28448-28459
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Regulation of UHRF1 by dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p): inhibition of bladder cancer cell aggressiveness

Regulation of UHRF1 by dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p): inhibition of bladder cancer cell aggressiveness

https://doi.org/10.18632/oncotarget.8668

Ryosuke Matsushita, Hirofumi Yoshino, Hideki Enokida, Yusuke Goto, Kazutaka Miyamoto, Masaya Yonemori, Satoru Inoguchi, Masayuki Nakagawa,  and Naohiko Seki
28460-28487
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ProNGF is a potential diagnostic biomarker for thyroid cancer

ProNGF is a potential diagnostic biomarker for thyroid cancer

https://doi.org/10.18632/oncotarget.8652

Sam Faulkner, Severine Roselli, Yohann Demont, Jay Pundavela, Genevieve Choquet, Philippe Leissner, Christopher Oldmeadow, John Attia, Marjorie M. Walker,  and Hubert Hondermarck
28488-28497
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Yin Yang-1 increases apoptosis through Bax activation in pancreatic cancer cells

Yin Yang-1 increases apoptosis through Bax activation in pancreatic cancer cells

https://doi.org/10.18632/oncotarget.8654

Jing-Jing Zhang, Yi Zhu, Chuang Yang, Xian Liu, Yun-Peng Peng, Kui-Rong Jiang, Yi Miao,  and Ze-Kuan Xu
28498-28509
Abstract  |  PDF  |  HTML  |  Order a Reprint

A loss-of-function genetic screening identifies novel mediators of thyroid cancer cell viability

A loss-of-function genetic screening identifies novel mediators of thyroid cancer cell viability

https://doi.org/10.18632/oncotarget.8577

Maria Carmela Cantisani, Alessia Parascandolo, Merja Perälä, Chiara Allocca, Vidal Fey, Niko Sahlberg, Francesco Merolla, Fulvio Basolo, Mikko O. Laukkanen, Olli Pekka Kallioniemi, Massimo Santoro,  and Maria Domenica Castellone
28510-28522
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prediction of survival prognosis of non-small cell lung cancer by APE1 through regulation of epithelial-mesenchymal transition

Prediction of survival prognosis of non-small cell lung cancer by APE1 through regulation of epithelial-mesenchymal transition

https://doi.org/10.18632/oncotarget.8660

Xi Wei, Qing Li, Ying Li, Wei Duan, Chongbiao Huang, Xiangqian Zheng, Lei Sun, Jingtao Luo, Dong Wang, Sheng Zhang, Xiaojie Xin,  and Ming Gao
28523-28539
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PRSS8 methylation and its significance in esophageal squamous cell carcinoma

PRSS8 methylation and its significance in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.8677

Yonghua Bao, Qian Wang, Yongchen Guo, Zhiguo Chen, Kai Li, Yiqiong Yang, Huijuan Zhang, Huali Dong, Kui Shen,  and Wancai Yang
28540-28555
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prospective validation of microRNA signatures for detecting pancreatic malignant transformation in endoscopic-ultrasound guided fine-needle aspiration biopsies

Prospective validation of microRNA signatures for detecting pancreatic malignant transformation in endoscopic-ultrasound guided fine-needle aspiration biopsies

https://doi.org/10.18632/oncotarget.8699

Adam E. Frampton, Jonathan Krell, Mireia Mato Prado, Tamara M.H. Gall, Nima Abbassi-Ghadi, Giovanna Del Vecchio Blanco, Niccola Funel, Elisa Giovannetti, Leandro Castellano, Mohamed Basyouny, Nagy A. Habib, Harry Kaltsidis, Panagiotis Vlavianos, Justin Stebbing,  and Long R. Jiao
28556-28569
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Intratumoral expression of CCR3 in breast cancer is associated with improved relapse-free survival in luminal-like disease

Intratumoral expression of CCR3 in breast cancer is associated with improved relapse-free survival in luminal-like disease

https://doi.org/10.18632/oncotarget.8680

Di-He Gong, Lei Fan, Hai-Yan Chen, Ke-Feng Ding,  and Ke-Da Yu
28570-28578
Abstract  |  PDF  |  HTML  |  Order a Reprint

TRIM29 overexpression is associated with poor prognosis and promotes tumor progression by activating Wnt/β-catenin pathway in cervical cancer

TRIM29 overexpression is associated with poor prognosis and promotes tumor progression by activating Wnt/β-catenin pathway in cervical cancer

https://doi.org/10.18632/oncotarget.8686

Rui Xu, Jingye Hu, Tiansong Zhang, Chao Jiang,  and Hui-Yun Wang
28579-28591
Abstract  |  PDF  |  HTML  |  Order a Reprint

ΔNp63α induces the expression of FAT2 and Slug to promote tumor invasion

ΔNp63α induces the expression of FAT2 and Slug to promote tumor invasion

https://doi.org/10.18632/oncotarget.8696

Tuyen T. Dang, Jill M. Westcott, Erin A. Maine, Mohammed Kanchwala, Chao Xing,  and Gray W. Pearson
28592-28611
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Changes in cytochrome P450s-mediated drug clearance in patients with hepatocellular carcinoma in vitro and in vivo: a bottom-up approach

Changes in cytochrome P450s-mediated drug clearance in patients with hepatocellular carcinoma in vitro and in vivo: a bottom-up approach

https://doi.org/10.18632/oncotarget.8704

Jie Gao, Jun Zhou, Xiao-Pei He, Yun-Fei Zhang, Na Gao, Xin Tian, Yan Fang, Qiang Wen, Lin-Jing Jia, Han Jin,  and Hai-Ling Qiao
28612-28623
Abstract  |  PDF  |  HTML  |  Order a Reprint

The Mbd4 DNA glycosylase protects mice from inflammation-driven colon cancer and tissue injury

The Mbd4 DNA glycosylase protects mice from inflammation-driven colon cancer and tissue injury

https://doi.org/10.18632/oncotarget.8721

Amy Marie Yu, Jennifer A. Calvo, Suresh Muthupalani,  and Leona D. Samson
28624-28636
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Associations between the MDM2 promoter P1 polymorphism del1518 (rs3730485) and incidence of cancer of the breast, lung, colon and prostate

Associations between the MDM2 promoter P1 polymorphism del1518 (rs3730485) and incidence of cancer of the breast, lung, colon and prostate

https://doi.org/10.18632/oncotarget.8705

Liv B. Gansmo, Lars Vatten, Pål Romundstad, Kristian Hveem, Bríd M. Ryan, Curtis C. Harris, Stian Knappskog,  and Per E. Lønning
28637-28646
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Serum miR-125b is a non-invasive predictive biomarker of the pre-operative chemoradiotherapy responsiveness in patients with rectal adenocarcinoma

Serum miR-125b is a non-invasive predictive biomarker of the pre-operative chemoradiotherapy responsiveness in patients with rectal adenocarcinoma

https://doi.org/10.18632/oncotarget.8725

Edoardo D’Angelo, Matteo Fassan, Isacco Maretto, Salvatore Pucciarelli, Carlo Zanon, Maura Digito, Massimo Rugge, Donato Nitti,  and Marco Agostini
28647-28657
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumour-specific triple-regulated oncolytic herpes virus to target glioma

Tumour-specific triple-regulated oncolytic herpes virus to target glioma

https://doi.org/10.18632/oncotarget.8637

Zahid M. Delwar, Guoyu Liu, Yvonne Kuo, Cleo Lee, Luke Bu, Paul S. Rennie,  and William W. Jia
28658-28669
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A reciprocal regulatory circuit between CD44 and FGFR2 via c-myc controls gastric cancer cell growth

A reciprocal regulatory circuit between CD44 and FGFR2 via c-myc controls gastric cancer cell growth

https://doi.org/10.18632/oncotarget.8764

Jihyun Park, Sun Young Kim, Ha-Jung Kim, Kyoung-Mee Kim, Eun Young Choi,  and Myung-Soo Kang
28670-28683
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hsp90 inhibition increases SOCS3 transcript and regulates migration and cell death in chronic lymphocytic leukemia

Hsp90 inhibition increases SOCS3 transcript and regulates migration and cell death in chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.8760

Timothy L. Chen, Nikhil Gupta, Amy Lehman, Amy S. Ruppert, Lianbo Yu, Christopher C. Oakes, Rainer Claus, Christoph Plass, Kami J. Maddocks, Leslie Andritsos, Jeffery A. Jones, David M. Lucas, Amy J. Johnson, John C. Byrd,  and Erin Hertlein
28684-28696
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reviews

Targeting the CCL2-CCR2 signaling axis in cancer metastasis

Targeting the CCL2-CCR2 signaling axis in cancer metastasis

https://doi.org/10.18632/oncotarget.7376

Su Yin Lim, Arseniy E. Yuzhalin, Alex N. Gordon-Weeks,  and Ruth J. Muschel
28697-28710
Abstract  |  PDF  |  HTML  |  Order a Reprint

The RNA helicase A in malignant transformation

The RNA helicase A in malignant transformation

https://doi.org/10.18632/oncotarget.7377

Marco Fidaleo, Elisa De Paola,  and Maria Paola Paronetto
28711-28723
Abstract  |  PDF  |  HTML  |  Order a Reprint

HMGA1-pseudogenes and cancer

HMGA1-pseudogenes and cancer

https://doi.org/10.18632/oncotarget.7427

Marco De Martino, Floriana Forzati, Claudio Arra, Alfredo Fusco,  and Francesco Esposito
28724-28735
Abstract  |  PDF  |  HTML  |  Order a Reprint

Important roles of P2Y receptors in the inflammation and cancer of digestive system

Important roles of P2Y receptors in the inflammation and cancer of digestive system

https://doi.org/10.18632/oncotarget.7518

Han-Xing Wan, Jian-Hong Hu, Rei Xie, Shi-Ming Yang,  and Hui Dong
28736-28747
Abstract  |  PDF  |  HTML  |  Order a Reprint

Exosomes isolation and characterization in serum is feasible in non-small cell lung cancer patients: critical analysis of evidence and potential role in clinical practice

Exosomes isolation and characterization in serum is feasible in non-small cell lung cancer patients: critical analysis of evidence and potential role in clinical practice

https://doi.org/10.18632/oncotarget.7638

Simona Taverna, Marco Giallombardo, Ignacio Gil-Bazo, Anna Paola Carreca, Marta Castiglia, Jorge Chacártegui, Antonio Araujo, Riccardo Alessandro, Patrick Pauwels, Marc Peeters,  and Christian Rolfo
28748-28760
Abstract  |  PDF  |  HTML  |  Order a Reprint

Corrections

Correction: 5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53

Correction: 5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53

https://doi.org/10.18632/oncotarget.9248

Birce Akpinar, Ethiene V. Bracht, Dorin Reijnders, Barbora Safarikova, Iva Jelinkova, Alf Grandien, Alena Hyrslova Vaculova, Boris Zhivotovsky,  and Magnus Olsson
28761-28762
Correction  |  PDF


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