Oncotarget

Vol 7, No 18

May 3, 2016

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Differential localization of glioblastoma subtype: implications on glioblastoma pathogenesis. See Steed et al.

Table of Contents

Priority Research Papers

Differential localization of glioblastoma subtype: implications on glioblastoma pathogenesis

Differential localization of glioblastoma subtype: implications on glioblastoma pathogenesis

https://doi.org/10.18632/oncotarget.8551

Tyler C. Steed, Jeffrey M. Treiber, Kunal Patel, Valya Ramakrishnan, Alexander Merk, Amanda R. Smith, Bob S. Carter, Anders M. Dale, Lionel M. L. Chow,  and Clark C. Chen
24899-24907
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Research Papers: Gerotarget (Focus on Aging)

Type I collagen aging impairs discoidin domain receptor 2-mediated tumor cell growth suppression

Type I collagen aging impairs discoidin domain receptor 2-mediated tumor cell growth suppression

https://doi.org/10.18632/oncotarget.8795

Charles Saby, Emilie Buache, Sylvie Brassart-Pasco, Hassan El Btaouri, Marie-Pierre Courageot, Laurence Van Gulick, Roselyne Garnotel, Pierre Jeannesson,  and Hamid Morjani
24908-24927
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Lifelong challenge of calcium homeostasis in male mice lacking TRPV5 leads to changes in bone and calcium metabolism

Lifelong challenge of calcium homeostasis in male mice lacking TRPV5 leads to changes in bone and calcium metabolism

https://doi.org/10.18632/oncotarget.8779

Bram C.J. van der Eerden, W. Nadia H. Koek, Paul Roschger, M. Carola Zillikens, Jan H. Waarsing, Annemiete van der Kemp, Marijke Schreuders-Koedam, Nadja Fratzl-Zelman, Pieter J.M. Leenen, Joost G.J. Hoenderop, Klaus Klaushofer, René J.M. Bindels,  and Johannes P.T.M. van Leeuwen
24928-24941
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CLEC4C p.K210del variant causes impaired cell surface transport in plasmacytoid dendritic cells of amyotrophic lateral sclerosis

CLEC4C p.K210del variant causes impaired cell surface transport in plasmacytoid dendritic cells of amyotrophic lateral sclerosis

https://doi.org/10.18632/oncotarget.7886

Su Min Lim, Young-Eun Kim, Won Jun Choi, Ki-Wook Oh, Min-Young Noh, Min-Soo Kwon, Minyeop Nahm, Namshin Kim, Chang-Seok Ki,  and Seung Hyun Kim
24942-24949
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Research Papers: Pathology

A new immunohistochemistry prognostic score (IPS) for recurrence and survival in resected pancreatic neuroendocrine tumors (PanNET)

A new immunohistochemistry prognostic score (IPS) for recurrence and survival in resected pancreatic neuroendocrine tumors (PanNET)

https://doi.org/10.18632/oncotarget.7436

Antonio Viúdez, Filipe L.F. Carvalho, Zahra Maleki, Marianna Zahurak, Daniel Laheru, Alejandro Stark, Nilofer Z. Azad, Christopher L. Wolfgang, Stephen Baylin, James G. Herman,  and Ana De Jesus-Acosta
24950-24961
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Research Papers: Immunology

Mycobacterium tuberculosis Rv3628 drives Th1-type T cell immunity via TLR2-mediated activation of dendritic cells and displays vaccine potential against the hyper-virulent Beijing K strain

Mycobacterium tuberculosis Rv3628 drives Th1-type T cell immunity via TLR2-mediated activation of dendritic cells and displays vaccine potential against the hyper-virulent Beijing K strain

https://doi.org/10.18632/oncotarget.8771

Woo Sik Kim, Jong-Seok Kim, Seung Bin Cha, Hongmin Kim, Kee Woong Kwon, So Jeong Kim, Seung Jung Han, Soo Young Choi, Sang-Nae Cho, Jong-Hwan Park,  and Sung Jae Shin
24962-24982
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Down-regulating cyclin-dependent kinase 9 of alloreactive CD4+ T cells prolongs allograft survival

Down-regulating cyclin-dependent kinase 9 of alloreactive CD4+ T cells prolongs allograft survival

https://doi.org/10.18632/oncotarget.8804

Yang Zhan, Yeming Han, Hukui Sun, Ting Liang, Chao Zhang, Jing Song,  and Guihua Hou
24983-24994
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Research Papers: Autophagy and Cell Death

Essential role for acid sphingomyelinase-inhibited autophagy in melanoma response to cisplatin

Essential role for acid sphingomyelinase-inhibited autophagy in melanoma response to cisplatin

https://doi.org/10.18632/oncotarget.8735

Davide Cervia, Emma Assi, Clara De Palma, Matteo Giovarelli, Laura Bizzozero, Sarah Pambianco, Ilaria Di Renzo, Silvia Zecchini, Claudia Moscheni, Chiara Vantaggiato, Patrizia Procacci, Emilio Clementi,  and Cristiana Perrotta
24995-25009
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Reviews: Gerotarget (Focus on Aging)

Characterization and redox mechanism of asthma in the elderly

Characterization and redox mechanism of asthma in the elderly

https://doi.org/10.18632/oncotarget.7075

Li Zuo, Benjamin K. Pannell,  and Zewen Liu
25010-25021
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Reviews

Cell polarity signaling in the plasticity of cancer cell invasiveness

Cell polarity signaling in the plasticity of cancer cell invasiveness

https://doi.org/10.18632/oncotarget.7214

Aneta Gandalovičová, Tomáš Vomastek, Daniel Rosel,  and Jan Brábek
25022-25049
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Squamous cell carcinomas of the lung and of the head and neck: new insights on molecular characterization

Squamous cell carcinomas of the lung and of the head and neck: new insights on molecular characterization

https://doi.org/10.18632/oncotarget.7732

Valentina Polo, Giulia Pasello, Stefano Frega, Adolfo Favaretto, Haralabos Koussis, Pierfranco Conte,  and Laura Bonanno
25050-25063
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Oncogenic kinase fusions: an evolving arena with innovative clinical opportunities

Oncogenic kinase fusions: an evolving arena with innovative clinical opportunities

https://doi.org/10.18632/oncotarget.7853

Fabrizio Tabbò, Marco Pizzi, Peter W. Kyriakides, Bruce Ruggeri,  and Giorgio Inghirami
25064-25086
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Research Papers

Molecular alterations in hepatocellular carcinoma associated with hepatitis B and hepatitis C infections

Molecular alterations in hepatocellular carcinoma associated with hepatitis B and hepatitis C infections

https://doi.org/10.18632/oncotarget.7837

Maria Lina Tornesello, Luigi Buonaguro, Francesco Izzo,  and Franco M. Buonaguro
25087-25102
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ImmunoPET helps predicting the efficacy of antibody-drug conjugates targeting TENB2 and STEAP1

ImmunoPET helps predicting the efficacy of antibody-drug conjugates targeting TENB2 and STEAP1

https://doi.org/10.18632/oncotarget.8390

Simon-Peter Williams, Annie Ogasawara, Jeff N. Tinianow, Judith E. Flores, David Kan, Jeffrey Lau, MaryAnn Go, Alexander N. Vanderbilt, Herman S. Gill, Li Miao, Joshua Goldsmith, Bonnee Rubinfeld, Weiguang Mao, Ron Firestein, Shang-Fan Yu, Jan Marik,  and Anton Terwisscha van G.T. Scheltinga
25103-25112
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Src drives the Warburg effect and therapy resistance by inactivating pyruvate dehydrogenase through tyrosine-289 phosphorylation

Src drives the Warburg effect and therapy resistance by inactivating pyruvate dehydrogenase through tyrosine-289 phosphorylation

https://doi.org/10.18632/oncotarget.7159

Yue Jin, Qingsong Cai, Anitha K. Shenoy, Sangbin Lim, Ying Zhang, Steve Charles, Miriam Tarrash, Xueqi Fu, Sushama Kamarajugadda, Jose G. Trevino, Ming Tan,  and Jianrong Lu
25113-25124
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibiting cell migration and cell invasion by silencing the transcription factor ETS-1 in human bladder cancer

Inhibiting cell migration and cell invasion by silencing the transcription factor ETS-1 in human bladder cancer

https://doi.org/10.18632/oncotarget.7192

Li Liu, Yuchen Liu, Xintao Zhang, Mingwei Chen, Hanwei Wu, Muqi Lin, Yonghao Zhan, Chengle Zhuang, Junhao Lin, Jianfa Li, Wen Xu, Xing Fu, Qiaoxia Zhang, Xiaojuan Sun, Guoping Zhao,  and Weiren Huang
25125-25134
Abstract  |  PDF  |  HTML  |  Order a Reprint

The next generation of metastatic melanoma: uncovering the genetic variants for anti-BRAF therapy response

The next generation of metastatic melanoma: uncovering the genetic variants for anti-BRAF therapy response

https://doi.org/10.18632/oncotarget.7175

Rosamaria Pinto, Simona De Summa, Sabino Strippoli, Brunella Pilato, Amalia Azzariti, Gabriella Guida, Michele Guida,  and Stefania Tommasi
25135-25149
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Large-scale profiling of signalling pathways reveals an asthma specific signature in bronchial smooth muscle cells

Large-scale profiling of signalling pathways reveals an asthma specific signature in bronchial smooth muscle cells

https://doi.org/10.18632/oncotarget.7209

Elena Alexandrova, Giovanni Nassa, Giacomo Corleone, Anton Buzdin, Alexander M. Aliper, Nadezhda Terekhanova, Denis Shepelin, Alexander Zhavoronkov, Michael Tamm, Luciano Milanesi, Nicola Miglino, Alessandro Weisz,  and Pieter Borger
25150-25161
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Docosahexaenoic acid inhibits 12-O-tetradecanoylphorbol-13- acetate-induced fascin-1-dependent breast cancer cell migration by suppressing the PKCδ- and Wnt-1/β-catenin-mediated pathways

Docosahexaenoic acid inhibits 12-O-tetradecanoylphorbol-13- acetate-induced fascin-1-dependent breast cancer cell migration by suppressing the PKCδ- and Wnt-1/β-catenin-mediated pathways

https://doi.org/10.18632/oncotarget.7301

Chong-Kuei Lii, Jer-Wei Chang, Jia-Jing Chen, Haw-Wen Chen, Kai-Li Liu, Shu-Lan Yeh, Tsu-Shing Wang, Shu-Hui Liu, Chia-Han Tsai,  and Chien-Chun Li
25162-25179
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The matricellular protein CCN6 (WISP3) decreases Notch1 and suppresses breast cancer initiating cells

The matricellular protein CCN6 (WISP3) decreases Notch1 and suppresses breast cancer initiating cells

https://doi.org/10.18632/oncotarget.7734

Wei Huang, Emily E. Martin, Boris Burman, Maria E. Gonzalez,  and Celina G. Kleer
25180-25193
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Linneg Sca-1high CD49fhigh prostate cancer cells derived from the Hi-Myc mouse model are tumor-initiating cells with basal-epithelial characteristics and differentiation potential in vitro and in vivo

Linneg Sca-1high CD49fhigh prostate cancer cells derived from the Hi-Myc mouse model are tumor-initiating cells with basal-epithelial characteristics and differentiation potential in vitro and in vivo

https://doi.org/10.18632/oncotarget.7535

Achinto Saha, Jorge Blando, Irina Fernandez, Kaoru Kiguchi,  and John DiGiovanni
25194-25207
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Differential regulation of the c-Myc/Lin28 axis discriminates subclasses of rearranged MLL leukemia

Differential regulation of the c-Myc/Lin28 axis discriminates subclasses of rearranged MLL leukemia

https://doi.org/10.18632/oncotarget.8199

Lili Chen, Yuqing Sun, Jingya Wang, Hui Jiang,  and Andrew G. Muntean
25208-25223
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer

mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer

https://doi.org/10.18632/oncotarget.8279

Yaqing Chen, Jianchang Qian, Qun He, Hui Zhao, Lourdes Toral-Barza, Celine Shi, Xuesai Zhang, Jiang Wu,  and Ker Yu
25224-25240
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dynamic epigenetic changes to VHL occur with sunitinib in metastatic clear cell renal cancer

Dynamic epigenetic changes to VHL occur with sunitinib in metastatic clear cell renal cancer

https://doi.org/10.18632/oncotarget.8308

Grant D. Stewart, Thomas Powles, Christophe Van Neste, Alison Meynert, Fiach O’Mahony, Alexander Laird, Dieter Deforce, Filip Van Nieuwerburgh, Geert Trooskens, Wim Van Criekinge, Tim De Meyer,  and David J. Harrison
25241-25250
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Autocrine epiregulin activates EGFR pathway for lung metastasis via EMT in salivary adenoid cystic carcinoma

Autocrine epiregulin activates EGFR pathway for lung metastasis via EMT in salivary adenoid cystic carcinoma

https://doi.org/10.18632/oncotarget.7940

Shuli Liu, Dongxia Ye, Dongliang Xu, Yueling Liao, Ling Zhang, Liu Liu, Wenwen Yu, Yanan Wang, Yue He, Jingzhou Hu, Wenzheng Guo, Tong Wang, Beibei Sun, Hongyong Song, Huijing Yin, Jingyi Liu, Yadi Wu, Hanguang Zhu, Binhua P. Zhou, Jiong Deng,  and Zhiyuan Zhang
25251-25263
Abstract  |  PDF  |  HTML  |  Order a Reprint

Antibody-based targeting of alternatively spliced tissue factor: a new approach to impede the primary growth and spread of pancreatic ductal adenocarcinoma

Antibody-based targeting of alternatively spliced tissue factor: a new approach to impede the primary growth and spread of pancreatic ductal adenocarcinoma

https://doi.org/10.18632/oncotarget.7955

Dusten Unruh, Betül Ünlü, Clayton S. Lewis, Xiaoyang Qi, Zhengtao Chu, Robert Sturm, Ryan Keil, Syed A. Ahmad, Timofey Sovershaev, Mariette Adam, Patrick Van Dreden, Barry J. Woodhams, Divya Ramchandani, Georg F. Weber, Janusz W. Rak, Alisa S. Wolberg, Nigel Mackman, Henri H. Versteeg,  and Vladimir Y. Bogdanov
25264-25275
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-424 and miR-27a increase TRAIL sensitivity of acute myeloid leukemia by targeting PLAG1

MiR-424 and miR-27a increase TRAIL sensitivity of acute myeloid leukemia by targeting PLAG1

https://doi.org/10.18632/oncotarget.8252

Yan-ping Sun, Fei Lu, Xiao-yu Han, Min Ji, Ying Zhou, A-min Zhang, Hong-chun Wang, Dao-xin Ma,  and Chun-yan Ji
25276-25290
Abstract  |  PDF  |  HTML  |  Order a Reprint

Genetic variants of GADD45A, GADD45B and MAPK14 predict platinum-based chemotherapy-induced toxicities in Chinese patients with non-small cell lung cancer

Genetic variants of GADD45A, GADD45B and MAPK14 predict platinum-based chemotherapy-induced toxicities in Chinese patients with non-small cell lung cancer

https://doi.org/10.18632/oncotarget.8052

Ming Jia, Meiling Zhu, Mengyun Wang, Menghong Sun, Ji Qian, Fei Ding, Jianhua Chang,  and Qingyi Wei
25291-25303
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PGE2-EP3 signaling pathway contributes to protective effects of misoprostol on cerebral injury in APP/PS1 mice

PGE2-EP3 signaling pathway contributes to protective effects of misoprostol on cerebral injury in APP/PS1 mice

https://doi.org/10.18632/oncotarget.8284

Xiaoyan Tian, Chaonan Ji, Ying Luo, Yang Yang, Shengnan Kuang, Shaoshan Mai, Jie Ma,  and Junqing Yang
25304-25314
Abstract  |  PDF  |  HTML  |  Order a Reprint

Characterization of site-specific glycosylation of secreted proteins associated with multi-drug resistance of gastric cancer

Characterization of site-specific glycosylation of secreted proteins associated with multi-drug resistance of gastric cancer

https://doi.org/10.18632/oncotarget.8287

Jian Wu, Hongqiang Qin, Ting Li, Kai Cheng, Jiaqiang Dong, Miaomiao Tian, Na Chai, Hao Guo, Jinjing Li, Xin You, Mingming Dong, Mingliang Ye, Yongzhan Nie, Hanfa Zou,  and Daiming Fan
25315-25327
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CCL20 mediates RANK/RANKL-induced epithelial-mesenchymal transition in endometrial cancer cells

CCL20 mediates RANK/RANKL-induced epithelial-mesenchymal transition in endometrial cancer cells

https://doi.org/10.18632/oncotarget.8291

Yao Liu, Jing Wang, Ting Ni, Lihua Wang, Yudong Wang,  and Xiao Sun
25328-25339
Abstract  |  PDF  |  HTML  |  Order a Reprint

Mining distinct aldehyde dehydrogenase 1 (ALDH1) isoenzymes in gastric cancer

Mining distinct aldehyde dehydrogenase 1 (ALDH1) isoenzymes in gastric cancer

https://doi.org/10.18632/oncotarget.8294

Jia-Xin Shen, Jing Liu, Guan-Wu Li, Yi-Teng Huang,  and Hua-Tao Wu
25340-25349
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ftx non coding RNA-derived miR-545 promotes cell proliferation by targeting RIG-I in hepatocellular carcinoma

Ftx non coding RNA-derived miR-545 promotes cell proliferation by targeting RIG-I in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.8129

Zhikui Liu, Changwei Dou, Bowen Yao, Meng Xu, Linglong Ding, Yufeng Wang, Yuli Jia, Qing Li, Hongyong Zhang, Kangsheng Tu, Tao Song,  and Qingguang Liu
25350-25365
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Chronic TGFβ stimulation promotes the metastatic potential of lung cancer cells by Snail protein stabilization through integrin β3-Akt-GSK3β signaling

Chronic TGFβ stimulation promotes the metastatic potential of lung cancer cells by Snail protein stabilization through integrin β3-Akt-GSK3β signaling

https://doi.org/10.18632/oncotarget.8295

Gab-Yong Bae, Soon-Ki Hong, Jeong-Rak Park, Ok-Seon Kwon, Keun-Tae Kim, JaeHyung Koo, Ensel Oh,  and Hyuk-Jin Cha
25366-25376
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oxidative stress at low levels can induce clustered DNA lesions leading to NHEJ mediated mutations

Oxidative stress at low levels can induce clustered DNA lesions leading to NHEJ mediated mutations

https://doi.org/10.18632/oncotarget.8298

Vyom Sharma, Leonard B. Collins, Ting-huei Chen, Natalie Herr, Shunichi Takeda, Wei Sun, James A Swenberg,  and Jun Nakamura
25377-25390
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gelsolin-mediated activation of PI3K/Akt pathway is crucial for hepatocyte growth factor-induced cell scattering in gastric carcinoma

Gelsolin-mediated activation of PI3K/Akt pathway is crucial for hepatocyte growth factor-induced cell scattering in gastric carcinoma

https://doi.org/10.18632/oncotarget.8603

Baohua Huang, Shuo Deng, Ser Yue Loo, Arpita Datta, Yan Lin Yap, Benedict Yan, Chia Huey Ooi, Thuy Duong Dinh, Jingli Zhuo, Lalchhandami Tochhawng, Suma Gopinadhan, Tamilarasi Jegadeesan, Patrick Tan, Manuel Salto-Tellez, Wei Peng Yong, Richie Soong, Khay Guan Yeoh, Yaw Chong Goh, Peter E. Lobie, Henry Yang, Alan Prem Kumar, Sutherland K. Maciver, Jimmy B.Y. So,  and Celestial T. Yap
25391-25407
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Salivary HOTAIR and PVT1 as novel biomarkers for early pancreatic cancer

Salivary HOTAIR and PVT1 as novel biomarkers for early pancreatic cancer

https://doi.org/10.18632/oncotarget.8323

Zijun Xie, Xiaoliang Chen, Jianzhong Li, Yunwei Guo, Haijiao Li, Xuemei Pan, Jie Jiang, Huiling Liu,  and Bin Wu
25408-25419
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

XB130 deficiency enhances lipopolysaccharide-induced septic response and acute lung injury

XB130 deficiency enhances lipopolysaccharide-induced septic response and acute lung injury

https://doi.org/10.18632/oncotarget.8326

Hiroaki Toba, Tereza Tomankova, Yingchun Wang, Xiaohui Bai, Hae-Ra Cho, Zhehong Guan, Oyedele A. Adeyi, Feng Tian, Shaf Keshavjee,  and Mingyao Liu
25420-25431
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

mTOR regulates proteasomal degradation and Dp1/E2F1- mediated transcription of KPNA2 in lung cancer cells

mTOR regulates proteasomal degradation and Dp1/E2F1- mediated transcription of KPNA2 in lung cancer cells

https://doi.org/10.18632/oncotarget.8170

Chun-I Wang, Yan-Yu Chen, Chih-Liang Wang, Jau-Song Yu, Yu-Sun Chang,  and Chia-Jung Yu
25432-25442
Abstract  |  PDF  |  HTML  |  Order a Reprint

Regulation of ErbB2 localization and function in breast cancer cells by ERM proteins

Regulation of ErbB2 localization and function in breast cancer cells by ERM proteins

https://doi.org/10.18632/oncotarget.8327

Nagham Asp, Audun Kvalvaag, Kirsten Sandvig,  and Sascha Pust
25443-25460
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preoperative serum fibrinogen is an independent prognostic factor in operable esophageal cancer

Preoperative serum fibrinogen is an independent prognostic factor in operable esophageal cancer

https://doi.org/10.18632/oncotarget.8171

Shui-Shen Zhang, Yi-Yan Lei, Xiao-Li Cai, Hong Yang, Xin Xia, Kong- Jia Luo, Chun-Hua Su, Jian-Yong Zou, Bo Zeng, Yi Hu,  and Hong-He Luo
25461-25469
Abstract  |  PDF  |  HTML  |  Order a Reprint

Association of genetic variants in lncRNA H19 with risk of colorectal cancer in a Chinese population

Association of genetic variants in lncRNA H19 with risk of colorectal cancer in a Chinese population

https://doi.org/10.18632/oncotarget.8330

Shuwei Li, Yibing Hua, Jing Jin, Haixiao Wang, Mulong Du, Lingjun Zhu, Haiyan Chu, Zhengdong Zhang,  and Meilin Wang
25470-25477
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activation of anaphase-promoting complex by p53 induces a state of dormancy in cancer cells against chemotherapeutic stress

Activation of anaphase-promoting complex by p53 induces a state of dormancy in cancer cells against chemotherapeutic stress

https://doi.org/10.18632/oncotarget.8172

Yafei Dai, Lujuan Wang, Jingqun Tang, Pengfei Cao, Zhaohui Luo, Jun Sun, Abraha Kiflu, Buqing Sai, Meili Zhang, Fan Wang, Guiyuan Li,  and Juanjuan Xiang
25478-25492
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel scoring system predicts adjuvant chemolipiodolization benefit for hepatocellular carcinoma patients after hepatectomy

A novel scoring system predicts adjuvant chemolipiodolization benefit for hepatocellular carcinoma patients after hepatectomy

https://doi.org/10.18632/oncotarget.8333

Li-feng Huang, Xianglei Xing, Dong Wu, Yong Xia, Jun Li, Kui Wang, Zhen-lin Yan, Xu-ying Wan, Le-hua Shi, Tian Yang, Wan Yee Lau, Meng-chao Wu,  and Feng Shen
25493-25506
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ERK2 phosphorylation of EBNA1 serine 383 residue is important for EBNA1-dependent transactivation

ERK2 phosphorylation of EBNA1 serine 383 residue is important for EBNA1-dependent transactivation

https://doi.org/10.18632/oncotarget.8177

Ka-Won Noh, Jihyun Park, Eun Hye Joo, Eun Kyung Lee, Eun Young Choi,  and Myung-Soo Kang
25507-25515
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preoperative platelet to lymphocyte ratio is a valuable prognostic biomarker in patients with colorectal cancer

Preoperative platelet to lymphocyte ratio is a valuable prognostic biomarker in patients with colorectal cancer

https://doi.org/10.18632/oncotarget.8334

Jie You, Gui-Qi Zhu, Linka Xie, Wen-Yue Liu, Liang Shi, Ou-Chen Wang, Zong-Hai Huang, Martin Braddock, Gui-Long Guo,  and Ming-Hua Zheng
25516-25527
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association of single nucleotide polymorphism rs6983267 with the risk of prostate cancer

Association of single nucleotide polymorphism rs6983267 with the risk of prostate cancer

https://doi.org/10.18632/oncotarget.8186

Yuan Yang, Wenjing Wang, Liangcai Zhang, Shihua Zhang, Guiyou Liu, Yingcui Yu,  and Mingzhi Liao
25528-25534
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Small flexible structure for targeted delivery of therapeutic and imaging moieties in precision medicine

Small flexible structure for targeted delivery of therapeutic and imaging moieties in precision medicine

https://doi.org/10.18632/oncotarget.8335

Shaofan Hu, Wei Wang, Yanling Zhang, Bingjie Li, Xiuchun Qiu, Chaoxia Zou, Henry Ran, Fujun Zhang,  and Shi Ke
25535-25548
Abstract  |  PDF  |  HTML  |  Order a Reprint

Phase I trial evaluating the antiviral agent Cidofovir in combination with chemoradiation in cervical cancer patients

Phase I trial evaluating the antiviral agent Cidofovir in combination with chemoradiation in cervical cancer patients

https://doi.org/10.18632/oncotarget.8224

Eric Deutsch, Christine Haie-Meder, Mohamed Amine Bayar, Michele Mondini, Mélanie Laporte, Renaud Mazeron, Julien Adam, Andrea Varga, Gilles Vassal, Nicolas Magné, Cyrus Chargari, Emilie Lanoy, Patricia Pautier, Antonin Levy,  and Jean-Charles Soria
25549-25557
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Upregulation of long intergenic noncoding RNA 00673 promotes tumor proliferation via LSD1 interaction and repression of NCALD in non-small-cell lung cancer

Upregulation of long intergenic noncoding RNA 00673 promotes tumor proliferation via LSD1 interaction and repression of NCALD in non-small-cell lung cancer

https://doi.org/10.18632/oncotarget.8338

Xuefei Shi, Chenhui Ma, Qingqing Zhu, Dongmei Yuan, Ming Sun, Xiaoling Gu, Guannan Wu, Tangfeng Lv,  and Yong Song
25558-25575
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Interim analysis of postoperative chemoradiotherapy with capecitabine and oxaliplatin versus capecitabine alone for pathological stage II and III rectal cancer: a randomized multicenter phase III trial

Interim analysis of postoperative chemoradiotherapy with capecitabine and oxaliplatin versus capecitabine alone for pathological stage II and III rectal cancer: a randomized multicenter phase III trial

https://doi.org/10.18632/oncotarget.8226

Yan-Ru Feng, Yuan Zhu, Lu-Ying Liu, Wei-Hu Wang, Shu-Lian Wang, Yong-Wen Song, Xin Wang, Yuan Tang, Yue-Ping Liu, Hua Ren, Hui Fang, Shi-Ping Zhang, Xin-Fan Liu, Zi-Hao Yu, Ye-Xiong Li,  and Jing Jin
25576-25584
Abstract  |  PDF  |  HTML  |  Order a Reprint

FOXO4 and FOXD3 are predictive of prognosis in gastric carcinoma patients

FOXO4 and FOXD3 are predictive of prognosis in gastric carcinoma patients

https://doi.org/10.18632/oncotarget.8339

Jing Li, Zhonghua Jiang, Fang Han, Shenxiang Liu, Xin Yuan,  and Jiandong Tong
25585-25592
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cancer-associated fibroblasts promote non-small cell lung cancer cell invasion by upregulation of glucose-regulated protein 78 (GRP78) expression in an integrated bionic microfluidic device

Cancer-associated fibroblasts promote non-small cell lung cancer cell invasion by upregulation of glucose-regulated protein 78 (GRP78) expression in an integrated bionic microfluidic device

https://doi.org/10.18632/oncotarget.8232

Ting Yu, Zhe Guo, Hui Fan, Jing Song, Yuanbin Liu, Zhancheng Gao,  and Qi Wang
25593-25603
Abstract  |  PDF  |  HTML  |  Order a Reprint

Numb contributes to renal fibrosis by promoting tubular epithelial cell cycle arrest at G2/M

Numb contributes to renal fibrosis by promoting tubular epithelial cell cycle arrest at G2/M

https://doi.org/10.18632/oncotarget.8238

Fengxin Zhu, Wei Liu, Tang Li, Jiao Wan, Jianwei Tian, Zhanmei Zhou, Hao Li, Youhua Liu, Fan Fan Hou,  and Jing Nie
25604-25619
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Integrated epigenomic analyses of enhancer as well as promoter regions in gastric cancer

Integrated epigenomic analyses of enhancer as well as promoter regions in gastric cancer

https://doi.org/10.18632/oncotarget.8239

Su-Jin Baek, Mirang Kim, Dong-Hyuck Bae, Jeong-Hwan Kim, Hee-Jin Kim, Myoung-Eun Han, Sae-Ock Oh, Yong Sung Kim,  and Seon-Young Kim
25620-25631
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A window of opportunity study of potential tumor and soluble biomarkers of response to preoperative erlotinib in early stage non-small cell lung cancer

A window of opportunity study of potential tumor and soluble biomarkers of response to preoperative erlotinib in early stage non-small cell lung cancer

https://doi.org/10.18632/oncotarget.8350

Adrian G. Sacher, Lisa W. Le, Humberto Lara-Guerra, Thomas K. Waddell, Shingo Sakashita, Zhuo Chen, Lucia Kim, Tong Zhang, Suzanne Kamel-Reid, Alexandra Salvarrey, Gail Darling, Kazuhiro Yasufuku, Shaf Keshavjee, Marc de Perrot, Frances A. Shepherd, Geoffrey Liu, Ming Sound Tsao,  and Natasha B. Leighl
25632-25639
Abstract  |  PDF  |  HTML  |  Order a Reprint

Argon protects against hypoxic-ischemic brain injury in neonatal rats through activation of nuclear factor (erythroid-derived 2)-like 2

Argon protects against hypoxic-ischemic brain injury in neonatal rats through activation of nuclear factor (erythroid-derived 2)-like 2

https://doi.org/10.18632/oncotarget.8241

Hailin Zhao, Sian Mitchell, Sarah Ciechanowicz, Sinead Savage, Tianlong Wang, Xunming Ji,  and Daqing Ma
25640-25651
Abstract  |  PDF  |  HTML  |  Order a Reprint

Tumor suppressor Spred2 interaction with LC3 promotes autophagosome maturation and induces autophagy-dependent cell death

Tumor suppressor Spred2 interaction with LC3 promotes autophagosome maturation and induces autophagy-dependent cell death

https://doi.org/10.18632/oncotarget.8357

Ke Jiang, Min Liu, Guibin Lin, Beibei Mao, Wei Cheng, Han Liu, Jozsef Gal, Haining Zhu, Zengqiang Yuan, Wuguo Deng, Quentin Liu, Peng Gong, Xiaolin Bi,  and Songshu Meng
25652-25667
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long noncoding RNA MALAT1 promotes malignant development of esophageal squamous cell carcinoma by targeting β-catenin via Ezh2

Long noncoding RNA MALAT1 promotes malignant development of esophageal squamous cell carcinoma by targeting β-catenin via Ezh2

https://doi.org/10.18632/oncotarget.8257

Wei Wang, Yunan Zhu, Sanni Li, Xinfeng Chen, Guozhong Jiang, Zhibo Shen, Yamin Qiao, Liping Wang, Pengyuan Zheng,  and Yi Zhang
25668-25682
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Grapefruit-derived nanovectors deliver miR-18a for treatment of liver metastasis of colon cancer by induction of M1 macrophages

Grapefruit-derived nanovectors deliver miR-18a for treatment of liver metastasis of colon cancer by induction of M1 macrophages

https://doi.org/10.18632/oncotarget.8361

Yun Teng, Jingyao Mu, Xin Hu, Abhilash Samykutty, Xiaoying Zhuang, Zhongbin Deng, Lifeng Zhang, Pengxiao Cao, Jun Yan, Donald Miller,  and Huang-Ge Zhang
25683-25697
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Endogenous GAS6 and Mer receptor signaling regulate prostate cancer stem cells in bone marrow

Endogenous GAS6 and Mer receptor signaling regulate prostate cancer stem cells in bone marrow

https://doi.org/10.18632/oncotarget.8365

Younghun Jung, Ann M. Decker, Jingcheng Wang, Eunsohl Lee, Lulia A. Kana, Kenji Yumoto, Frank C. Cackowski, James Rhee, Peter Carmeliet, Laura Buttitta, Todd M. Morgan,  and Russell S. Taichman
25698-25711
Abstract  |  PDF  |  HTML  |  Order a Reprint

EFEMP1 is repressed by estrogen and inhibits the epithelial-mesenchymal transition via Wnt/β-catenin signaling in endometrial carcinoma

EFEMP1 is repressed by estrogen and inhibits the epithelial-mesenchymal transition via Wnt/β-catenin signaling in endometrial carcinoma

https://doi.org/10.18632/oncotarget.8263

Tingting Yang, Huilin Zhang, Haifeng Qiu, Bilan Li, Jingyun Wang, Guiqiang Du,  and Xiaoping Wan
25712-25725
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Androgen receptor regulates SRC expression through microRNA-203

Androgen receptor regulates SRC expression through microRNA-203

https://doi.org/10.18632/oncotarget.8366

Man Kit Siu, Wei-Yu Chen, Hong-Yuan Tsai, Hsiu-Lien Yeh, Juan Juan Yin, Shih-Yang Liu,  and Yen-Nien Liu
25726-25741
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sciellin mediates mesenchymal-to-epithelial transition in colorectal cancer hepatic metastasis

Sciellin mediates mesenchymal-to-epithelial transition in colorectal cancer hepatic metastasis

https://doi.org/10.18632/oncotarget.8264

Chuan-Kai Chou, Chi-Chen Fan, Pei-Shan Lin, Pei-Yu Liao, Jia-Chen Tung, Chang-Hsun Hsieh, Mien-Chie Hung, Chung-Hsuan Chen,  and Wei-Chao Chang
25742-25754
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Supra-complete surgery via dual intraoperative visualization approach (DiVA) prolongs patient survival in glioblastoma

Supra-complete surgery via dual intraoperative visualization approach (DiVA) prolongs patient survival in glioblastoma

https://doi.org/10.18632/oncotarget.8367

Ilker Y. Eyüpoglu, Nirjhar Hore, Andreas Merkel, Rolf Buslei, Michael Buchfelder,  and Nicolai Savaskan
25755-25768
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dissecting dysfunctional crosstalk pathways regulated by miRNAs during glioma progression

Dissecting dysfunctional crosstalk pathways regulated by miRNAs during glioma progression

https://doi.org/10.18632/oncotarget.8265

Yunpeng Zhang, Yanjun Xu, Feng Li, Xiang Li, Li Feng, Xinrui Shi, Lihua Wang,  and Xia Li
25769-25782
Abstract  |  PDF  |  HTML  |  Order a Reprint

Treatment of newly diagnosed B-cell origin primary CNS lymphoma with systemic R-IDARAM chemotherapy and intrathecal immunochemotherapy

Treatment of newly diagnosed B-cell origin primary CNS lymphoma with systemic R-IDARAM chemotherapy and intrathecal immunochemotherapy

https://doi.org/10.18632/oncotarget.8370

Liren Qian, Chunhui Zhou, Jianliang Shen, Jian Cen,  and Wenjie Yin
25783-25790
Abstract  |  PDF  |  HTML  |  Order a Reprint

Long noncoding RNAs as auxiliary biomarkers for gastric cancer screening: A pooled analysis of individual studies

Long noncoding RNAs as auxiliary biomarkers for gastric cancer screening: A pooled analysis of individual studies

https://doi.org/10.18632/oncotarget.8268

Zhaolei Cui, Yan Chen, Zhenzhou Xiao, Minhua Hu, Yingying Lin, Yansong Chen,  and Yuhong Zheng
25791-25800
Abstract  |  PDF  |  HTML  |  Order a Reprint

Twist promotes angiogenesis in pancreatic cancer by targeting miR-497/VEGFA axis

Twist promotes angiogenesis in pancreatic cancer by targeting miR-497/VEGFA axis

https://doi.org/10.18632/oncotarget.8269

An Liu, Chenggang Huang, Xuehong Cai, Jia Xu,  and Dinghua Yang
25801-25814
Abstract  |  PDF  |  HTML  |  Order a Reprint

Molecular insights into the OGG1 gene, a cancer risk modifier in BRCA1 and BRCA2 mutations carriers

Molecular insights into the OGG1 gene, a cancer risk modifier in BRCA1 and BRCA2 mutations carriers

https://doi.org/10.18632/oncotarget.8272

Carlos Benitez-Buelga, Tereza Vaclová, Sofia Ferreira, Miguel Urioste, Lucia Inglada-Perez, Nora Soberón, Maria A. Blasco, Ana Osorio,  and Javier Benitez
25815-25825
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The genetic difference between Western and Chinese urothelial cell carcinomas: infrequent FGFR3 mutation in Han Chinese patients

The genetic difference between Western and Chinese urothelial cell carcinomas: infrequent FGFR3 mutation in Han Chinese patients

https://doi.org/10.18632/oncotarget.8404

Xiaotian Yuan, Cheng Liu, Kun Wang, Li Liu, Tiantian Liu, Nan Ge, Feng Kong, Liu Yang, Magnus Björkholm, Yidong Fan, Shengtian Zhao,  and Dawei Xu
25826-25835
Abstract  |  PDF  |  HTML  |  Order a Reprint

The putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosis

The putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosis

https://doi.org/10.18632/oncotarget.8283

Tian-Hao Liu, Fang Zheng, Mu-Yan Cai, Lin Guo, Huan-Xin Lin, Jie-Wei Chen, Yi-Ji Liao, Hsiang-Fu Kung, Yi-Xin Zeng,  and Dan Xie
25836-25848
Abstract  |  PDF  |  HTML  |  Order a Reprint

TRPV4 channels regulate tumor angiogenesis via modulation of Rho/Rho kinase pathway

TRPV4 channels regulate tumor angiogenesis via modulation of Rho/Rho kinase pathway

https://doi.org/10.18632/oncotarget.8405

Roslin J. Thoppil, Holly C. Cappelli, Ravi K. Adapala, Anantha K. Kanugula, Sailaja Paruchuri,  and Charles K. Thodeti
25849-25861
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HDAC1 controls CIP2A transcription in human colorectal cancer cells

HDAC1 controls CIP2A transcription in human colorectal cancer cells

https://doi.org/10.18632/oncotarget.8406

Manjola Balliu, Cristina Cellai, Matteo Lulli, Anna Laurenzana, Eugenio Torre, Alessandro Maria Vannucchi,  and Francesco Paoletti
25862-25871
Abstract  |  PDF  |  HTML  |  Order a Reprint

HMGA2 overexpression plays a critical role in the progression of esophageal squamous carcinoma

HMGA2 overexpression plays a critical role in the progression of esophageal squamous carcinoma

https://doi.org/10.18632/oncotarget.8288

Antonio Palumbo Jr, Nathalia Meireles Da Costa, Francesco Esposito, Marco De Martino, Daniela D'Angelo, Vanessa Paiva Leite de Sousa, Ivanir Martins, Luiz Eurico Nasciutti, Alfredo Fusco,  and Luis Felipe Ribeiro Pinto
25872-25884
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dual inhibition of ATR and ATM potentiates the activity of trabectedin and lurbinectedin by perturbing the DNA damage response and homologous recombination repair

Dual inhibition of ATR and ATM potentiates the activity of trabectedin and lurbinectedin by perturbing the DNA damage response and homologous recombination repair

https://doi.org/10.18632/oncotarget.8292

Michelle Lima, Hana Bouzid, Daniele G. Soares, Frédéric Selle, Claire Morel, Carlos M. Galmarini, João A. P. Henriques, Annette K. Larsen,  and Alexandre E. Escargueil
25885-25901
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ILNCSIM: improved lncRNA functional similarity calculation model

ILNCSIM: improved lncRNA functional similarity calculation model

https://doi.org/10.18632/oncotarget.8296

Yu-An Huang, Xing Chen, Zhu-Hong You, De-Shuang Huang,  and Keith C.C. Chan
25902-25914
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Loss of HIF-1α in macrophages attenuates AhR/ARNT-mediated tumorigenesis in a PAH-driven tumor model

Loss of HIF-1α in macrophages attenuates AhR/ARNT-mediated tumorigenesis in a PAH-driven tumor model

https://doi.org/10.18632/oncotarget.8297

Nina Henke, Nerea Ferreirós, Gerd Geisslinger, Martina G. Ding, Silke Essler, Dominik C. Fuhrmann, Theresa Geis, Dmitry Namgaladze, Nathalie Dehne,  and Bernhard Brüne
25915-25929
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer

miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer

https://doi.org/10.18632/oncotarget.8412

Yinghong Pan, Gordon Robertson, Lykke Pedersen, Emilia Lim, Anadulce Hernandez-Herrera, Amy C. Rowat, Sagar L. Patil, Clara K. Chan, Yunfei Wen, Xinna Zhang, Upal Basu-Roy, Alka Mansukhani, Andy Chu, Payal Sipahimalani, Reanne Bowlby, Denise Brooks, Nina Thiessen, Cristian Coarfa, Yussanne Ma, Richard A. Moore, Jacquie E. Schein, Andrew J. Mungall, Jinsong Liu, Chad V. Pecot, Anil K. Sood, Steven J.M. Jones, Marco A. Marra,  and Preethi H. Gunaratne
25930-25948
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A preoperative mathematic model for computed tomographic guided microwave ablation treatment of hepatic dome tumors

A preoperative mathematic model for computed tomographic guided microwave ablation treatment of hepatic dome tumors

https://doi.org/10.18632/oncotarget.8299

Fei Gao, Guo-Bao Wang, Zhan-Wang Xiang, Bin Yang, Jing-Bing Xue, Zhi-Qiang Mo, Zhi-Hui Zhong, Tao Zhang, Fu-Jun Zhang,  and Wei- Jun Fan
25949-25959
Abstract  |  PDF  |  HTML  |  Order a Reprint

Transcriptional regulation of the potential tumor suppressor ABI3 gene in thyroid carcinomas: interplay between methylation and NKX2-1 availability

Transcriptional regulation of the potential tumor suppressor ABI3 gene in thyroid carcinomas: interplay between methylation and NKX2-1 availability

https://doi.org/10.18632/oncotarget.8416

Lais Moraes, Ana Luiza R. Galrão, Ileana Rubió,  and Janete M. Cerutti
25960-25970
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Salidroside suppresses solar ultraviolet-induced skin inflammation by targeting cyclooxygenase-2

Salidroside suppresses solar ultraviolet-induced skin inflammation by targeting cyclooxygenase-2

https://doi.org/10.18632/oncotarget.8300

Dan Wu, Ping Yuan, Changshu Ke, Hua Xiong, Jingwen Chen, Jinguang Guo, Mingmin Lu, Yanyan Ding, Xiaoming Fan, Qiuhong Duan, Fei Shi,  and Feng Zhu
25971-25982
Abstract  |  PDF  |  HTML  |  Order a Reprint

A high-content EMT screen identifies multiple receptor tyrosine kinase inhibitors with activity on TGFβ receptor

A high-content EMT screen identifies multiple receptor tyrosine kinase inhibitors with activity on TGFβ receptor

https://doi.org/10.18632/oncotarget.8418

Carina Lotz-Jenne, Urs Lüthi, Sabine Ackerknecht, François Lehembre, Tobias Fink, Manuel Stritt, Matthias Wirth, Simona Pavan, Ruben Bill, Urs Regenass, Gerhard Christofori,  and Nathalie Meyer-Schaller
25983-26002
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Huaier extract synergizes with tamoxifen to induce autophagy and apoptosis in ER-positive breast cancer cells

Huaier extract synergizes with tamoxifen to induce autophagy and apoptosis in ER-positive breast cancer cells

https://doi.org/10.18632/oncotarget.8303

Wenwen Qi, Mingjuan Sun, Xiangnan Kong, Yaming Li, Xiaolong Wang, Shangge Lv, Xia Ding, Sumei Gao, Jinjing Cun, Chang Cai, Xiaoting Wang, Junfei Chen, Aijun Yin,  and Qifeng Yang
26003-26015
Abstract  |  PDF  |  HTML  |  Order a Reprint

miR-340 and ZEB1 negative feedback loop regulates TGF-β- mediated breast cancer progression

miR-340 and ZEB1 negative feedback loop regulates TGF-β- mediated breast cancer progression

https://doi.org/10.18632/oncotarget.8421

Li-Kun Hou, Yue Yu, Ye-Gong Xie, Jie Wang, Jie-Fei Mao, Bin Zhang, Xin Wang,  and Xu-Chen Cao
26016-26026
Abstract  |  PDF  |  HTML  |  Order a Reprint

Methylation-regulated miR-124-1 suppresses tumorigenesis in hepatocellular carcinoma by targeting CASC3

Methylation-regulated miR-124-1 suppresses tumorigenesis in hepatocellular carcinoma by targeting CASC3

https://doi.org/10.18632/oncotarget.8266

Ling Xu, Weiqi Dai, JingJing Li, Lei He, Fan Wang, Yujing Xia, Kan Chen, Sainan Li, Tong Liu, Jie Lu, Yingqun Zhou, Yugang Wang,  and Chuanyong Guo
26027-26041
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Volatile anaesthetics enhance the metastasis related cellular signalling including CXCR2 of ovarian cancer cells

Volatile anaesthetics enhance the metastasis related cellular signalling including CXCR2 of ovarian cancer cells

https://doi.org/10.18632/oncotarget.8304

Masae Iwasaki, Hailin Zhao, Tanweer Jaffer, Sandeep Unwith, Laura Benzonana, Qingquan Lian, Atsuhiro Sakamoto,  and Daqing Ma
26042-26056
Abstract  |  PDF  |  HTML  |  Order a Reprint

Smurf1 regulation of DAB2IP controls cell proliferation and migration

Smurf1 regulation of DAB2IP controls cell proliferation and migration

https://doi.org/10.18632/oncotarget.8424

Xiaoning Li, Xiangpeng Dai, Lixin Wan, Hiroyuki Inuzuka, Liankun Sun,  and Brian J. North
26057-26069
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of a three-miRNA signature as a blood-borne diagnostic marker for early diagnosis of lung adenocarcinoma

Identification of a three-miRNA signature as a blood-borne diagnostic marker for early diagnosis of lung adenocarcinoma

https://doi.org/10.18632/oncotarget.8429

Yang Wang, Hua Zhao, Xujie Gao, Feng Wei, Xinwei Zhang, Yanjun Su, Changli Wang, Hui Li,  and Xiubao Ren
26070-26086
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value of aberrant promoter hypermethylation of tumor-related genes in early-stage head and neck cancer

Prognostic value of aberrant promoter hypermethylation of tumor-related genes in early-stage head and neck cancer

https://doi.org/10.18632/oncotarget.8317

Kiyoshi Misawa, Daiki Mochizuki, Atsushi Imai, Shiori Endo, Masato Mima, Yuki Misawa, Takeharu Kanazawa, Thomas E. Carey,  and Hiroyuki Mineta
26087-26098
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Alu methylation serves as a biomarker for non-invasive diagnosis of glioma

Alu methylation serves as a biomarker for non-invasive diagnosis of glioma

https://doi.org/10.18632/oncotarget.8318

Jian Chen, Wei Huan, Hao Zuo, Longxiang Zhao, Chuanjun Huang, Xiaojiang Liu, Shiqiang Hou, Jing Qi,  and Wei Shi
26099-26106
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mutational analysis of single circulating tumor cells by next generation sequencing in metastatic breast cancer

Mutational analysis of single circulating tumor cells by next generation sequencing in metastatic breast cancer

https://doi.org/10.18632/oncotarget.8431

Francesca De Luca, Giada Rotunno, Francesca Salvianti, Francesca Galardi, Marta Pestrin, Stefano Gabellini, Lisa Simi, Irene Mancini, Alessandro Maria Vannucchi, Mario Pazzagli, Angelo Di Leo,  and Pamela Pinzani
26107-26119
Abstract  |  PDF  |  HTML  |  Order a Reprint

Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell death

Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell death

https://doi.org/10.18632/oncotarget.8319

Alix Dubois, Clemence Ginet, Nathan Furstoss, Amine Belaid, Mohamed Amine Hamouda, Wedjene El Manaa, Thomas Cluzeau, Sandrine Marchetti, Jean Ehrland Ricci, Arnaud Jacquel, Frederic Luciano, Mohsine Driowya, Rachid Benhida, Patrick Auberger,  and Guillaume Robert
26120-26136
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling

REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling

https://doi.org/10.18632/oncotarget.8433

Tzu-Ping Lin, Yi-Ting Chang, Sung-Yuan Lee, Mel Campbell, Tien-Chiao Wang, Shu-Huei Shen, Hsiao-Jen Chung, Yen-Hwa Chang, Allen W. Chiu, Chin-Chen Pan, Chi-Hung Lin, Cheng-Ying Chu, Hsing-Jien Kung, Chia-Yang Cheng,  and Pei-Ching Chang
26137-26151
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Slug inhibits the proliferation and tumor formation of human cervical cancer cells by up-regulating the p21/p27 proteins and down-regulating the activity of the Wnt/β-catenin signaling pathway via the trans-suppression Akt1/p-Akt1 expression

Slug inhibits the proliferation and tumor formation of human cervical cancer cells by up-regulating the p21/p27 proteins and down-regulating the activity of the Wnt/β-catenin signaling pathway via the trans-suppression Akt1/p-Akt1 expression

https://doi.org/10.18632/oncotarget.8434

Nan Cui, Wen-Ting Yang,  and Peng-Sheng Zheng
26152-26167
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic polymorphisms of immune checkpoint proteins PD-1 and TIM-3 are associated with survival of patients with hepatitis B virus-related hepatocellular carcinoma

Genetic polymorphisms of immune checkpoint proteins PD-1 and TIM-3 are associated with survival of patients with hepatitis B virus-related hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.8435

Zhu Li, Na Li, Fang Li, Zhihua Zhou, Jiao Sang, Zhao Jin, Huihui Liu, Qunying Han, Yi Lv,  and Zhengwen Liu
26168-26180
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Xenopatients show the need for precision medicine approach to chemotherapy in ovarian cancer

Xenopatients show the need for precision medicine approach to chemotherapy in ovarian cancer

https://doi.org/10.18632/oncotarget.8325

Jessica Erriquez, Martina Olivero, Gloria Mittica, Maria Stella Scalzo, Marco Vaira, Michele De Simone, Riccardo Ponzone, Dionyssios Katsaros, Massimo Aglietta, Raffaele Calogero, Maria Flavia Di Renzo,  and Giorgio Valabrega
26181-26191
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value and clinicopathologic characteristics of L1 cell adhesion molecule (L1CAM) in a large series of vulvar squamous cell carcinomas

Prognostic value and clinicopathologic characteristics of L1 cell adhesion molecule (L1CAM) in a large series of vulvar squamous cell carcinomas

https://doi.org/10.18632/oncotarget.8353

Marjolijn D. Trietsch, Maaike H.M. Oonk, Lukas J.A.C. Hawinkels, Rosalie Bor, Jaap D.H. van Eendenburg, Zina Ivanova, Alexander A.W. Peters, Hans W. Nijman, Katja N. Gaarenstroom,  and Tjalling Bosse
26192-26205
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Aberrantly activated Gli2-KIF20A axis is crucial for growth of hepatocellular carcinoma and predicts poor prognosis

Aberrantly activated Gli2-KIF20A axis is crucial for growth of hepatocellular carcinoma and predicts poor prognosis

https://doi.org/10.18632/oncotarget.8441

Chao Shi, Dengliang Huang, Nonghua Lu, Dan Chen, Minhong Zhang, Yehong Yan, Libin Deng, Quqin Lu, Hua Lu,  and Shiwen Luo
26206-26219
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Sumoylation of TCF21 downregulates the transcriptional activity of estrogen receptor-alpha

Sumoylation of TCF21 downregulates the transcriptional activity of estrogen receptor-alpha

https://doi.org/10.18632/oncotarget.8354

Xiang Ao, Shujing Li, Zhaowei Xu, Yangyang Yang, Min Chen, Xiao Jiang,  and Huijian Wu
26220-26234
Abstract  |  PDF  |  HTML  |  Order a Reprint

N-acetylaspartate (NAA) induces neuronal differentiation of SH-SY5Y neuroblastoma cell line and sensitizes it to chemotherapeutic agents

N-acetylaspartate (NAA) induces neuronal differentiation of SH-SY5Y neuroblastoma cell line and sensitizes it to chemotherapeutic agents

https://doi.org/10.18632/oncotarget.8454

Carmela Mazzoccoli, Vitalba Ruggieri, Tiziana Tataranni, Francesca Agriesti, Ilaria Laurenzana, Angelo Fratello, Nazzareno Capitanio,  and Claudia Piccoli
26235-26246
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LIM domain only 2 over-expression in prostate stromal cells facilitates prostate cancer progression through paracrine of Interleukin-11

LIM domain only 2 over-expression in prostate stromal cells facilitates prostate cancer progression through paracrine of Interleukin-11

https://doi.org/10.18632/oncotarget.8359

Chen-Yi Jiang, Jun-Jie Yu, Yuan Ruan, Xiao-Hai Wang, Wei Zhao, Xing-Jie Wang, Yi-Ping Zhu, Yuan Gao, Kui-Yuan Hao, Lei Chen, Bang-Min Han, Shu-Jie Xia,  and Fu-Jun Zhao
26247-26258
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Acquired resistance to the second-generation androgen receptor antagonist enzalutamide in castration-resistant prostate cancer

Acquired resistance to the second-generation androgen receptor antagonist enzalutamide in castration-resistant prostate cancer

https://doi.org/10.18632/oncotarget.8456

Steven Kregel, James L. Chen, Westin Tom, Venkatesh Krishnan, Jacob Kach, Hannah Brechka, Tim B. Fessenden, Masis Isikbay, Gladell P. Paner, Russell Z. Szmulewitz,  and Donald J. Vander Griend
26259-26274
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

E2F1 interactions with hHR23A inhibit its degradation and promote DNA repair

E2F1 interactions with hHR23A inhibit its degradation and promote DNA repair

https://doi.org/10.18632/oncotarget.8362

Randeep K. Singh,  and Lina Dagnino
26275-26292
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

APE1 polymorphic variants cause persistent genomic stress and affect cancer cell proliferation

APE1 polymorphic variants cause persistent genomic stress and affect cancer cell proliferation

https://doi.org/10.18632/oncotarget.8477

Lisa Lirussi, Giulia Antoniali, Chiara D’Ambrosio, Andrea Scaloni, Hilde Nilsen,  and Gianluca Tell
26293-26306
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma

Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.8368

Uddalak Bharadwaj, T. Kris Eckols, Xuejun Xu, Moses M. Kasembeli, Yunyun Chen, Makoto Adachi, Yongcheng Song, Qianxing Mo, Stephen Y. Lai,  and David J. Tweardy
26307-26330
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of melanocortin 1 receptor slows melanoma growth, reduces tumor heterogeneity and increases survival

Inhibition of melanocortin 1 receptor slows melanoma growth, reduces tumor heterogeneity and increases survival

https://doi.org/10.18632/oncotarget.8372

Rita G. Kansal, Matthew S. McCravy, Jacob H. Basham, Joshua A. Earl, Stacy L. McMurray, Chelsey J. Starner, Michael A. Whitt,  and Lorraine M. Albritton
26331-26345
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A combination of an anti-SLAMF6 antibody and ibrutinib efficiently abrogates expansion of chronic lymphocytic leukemia cells

A combination of an anti-SLAMF6 antibody and ibrutinib efficiently abrogates expansion of chronic lymphocytic leukemia cells

https://doi.org/10.18632/oncotarget.8378

Burcu Yigit, Peter J. Halibozek, Shih-Shih Chen, Michael S. O’Keeffe, Jon Arnason, David Avigan, Valter Gattei, Atul Bhan, Osman Cen, Richard Longnecker, Nicholas Chiorazzi, Ninghai Wang, Pablo Engel,  and Cox Terhorst
26346-26360
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IFN-α potentiates the direct and immune-mediated antitumor effects of epigenetic drugs on both metastatic and stem cells of colorectal cancer

IFN-α potentiates the direct and immune-mediated antitumor effects of epigenetic drugs on both metastatic and stem cells of colorectal cancer

https://doi.org/10.18632/oncotarget.8379

Maria Buoncervello, Giulia Romagnoli, Mariachiara Buccarelli, Alessandra Fragale, Elena Toschi, Stefania Parlato, Donatella Lucchetti, Daniele Macchia, Massimo Spada, Irene Canini, Massimo Sanchez, Mario Falchi, Martina Musella, Mauro Biffoni, Filippo Belardelli, Imerio Capone, Alessandro Sgambato, Lucia Ricci Vitiani,  and Lucia Gabriele
26361-26373
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Trichlorobenzene-substituted azaaryl compounds as novel FGFR inhibitors exhibiting potent antitumor activity in bladder cancer cells in vitro and in vivo

Trichlorobenzene-substituted azaaryl compounds as novel FGFR inhibitors exhibiting potent antitumor activity in bladder cancer cells in vitro and in vivo

https://doi.org/10.18632/oncotarget.8380

Chun-Han Chen, Yi-Min Liu, Shiow-Lin Pan, Yun-Ru Liu, Jing-Ping Liou,  and Yun Yen
26374-26387
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

microRNA-149 targets caspase-2 in glioma progression

microRNA-149 targets caspase-2 in glioma progression

https://doi.org/10.18632/oncotarget.8506

Xiaokun Shen, Jie Li, Wenfeng Liao, Jiwen Wang, Huanjun Chen, Yanli Yao, Houbao Liu,  and Kan Ding
26388-26399
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of mitochondrial 2-oxoglutarate dehydrogenase impairs viability of cancer cells in a cell-specific metabolism-dependent manner

Inhibition of mitochondrial 2-oxoglutarate dehydrogenase impairs viability of cancer cells in a cell-specific metabolism-dependent manner

https://doi.org/10.18632/oncotarget.8387

Victoria I. Bunik, Garik Mkrtchyan, Aneta Grabarska, Henry Oppermann, Danilo Daloso, Wagner L. Araujo, Malgorzata Juszczak, Wojciech Rzeski, Lucien Bettendorff, Alisdair R. Fernie, Jürgen Meixensberger, Andrzej Stepulak,  and Frank Gaunitz
26400-26421
Abstract  |  PDF  |  HTML  |  Order a Reprint

Peripheral lymphocyte subset variation predicts prostate cancer carbon ion radiotherapy outcomes

Peripheral lymphocyte subset variation predicts prostate cancer carbon ion radiotherapy outcomes

https://doi.org/10.18632/oncotarget.8389

Zhang-Ru Yang, Ning Zhao, Jin Meng, Ze-Liang Shi, Bing-Xin Li, Xian-Wei Wu, Ping Li, Qing Zhang, Xun-Bin Wei,  and Shen Fu
26422-26435
Abstract  |  PDF  |  HTML  |  Order a Reprint

Genetic variants of CHRNA5-A3 and CHRNB3-A6 predict survival of patients with advanced non-small cell lung cancer

Genetic variants of CHRNA5-A3 and CHRNB3-A6 predict survival of patients with advanced non-small cell lung cancer

https://doi.org/10.18632/oncotarget.8510

Yang Wang, Xiaonu Peng, Lijun Zhu, Likuan Hu,  and Yipeng Song
26436-26443
Abstract  |  PDF  |  HTML  |  Order a Reprint

Pre-miRNA variants as predictors of clinical outcome in patients with squamous cell carcinomas of the nonoropharynx

Pre-miRNA variants as predictors of clinical outcome in patients with squamous cell carcinomas of the nonoropharynx

https://doi.org/10.18632/oncotarget.8512

Chengyuan Wang, Erich M. Sturgis, Xingming Chen, Hongliang Zheng, Qingyi Wei,  and Guojun Li
26444-26453
Abstract  |  PDF  |  HTML  |  Order a Reprint

Analysis of disseminated tumor cells before and after platinum based chemotherapy in primary ovarian cancer. Do stem cell like cells predict prognosis?

Analysis of disseminated tumor cells before and after platinum based chemotherapy in primary ovarian cancer. Do stem cell like cells predict prognosis?

https://doi.org/10.18632/oncotarget.8524

Issam Chebouti, Christina Blassl, Pauline Wimberger, Hans Neubauer, Tanja Fehm, Rainer Kimmig,  and Sabine Kasimir‑Bauer
26454-26464
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic and epigenetic factors affect RET gene expression in breast cancer cell lines and influence survival in patients

Genetic and epigenetic factors affect RET gene expression in breast cancer cell lines and influence survival in patients

https://doi.org/10.18632/oncotarget.8417

Paola Griseri, Ornella Garrone, Alessandra Lo Sardo, Martino Monteverde, Marta Rusmini, Federica Tonissi, Marco Merlano, Paolo Bruzzi, Cristiana Lo Nigro,  and Isabella Ceccherini
26465-26479
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FOXM1 promotes invasion and migration of colorectal cancer cells partially dependent on HSPA5 transactivation

FOXM1 promotes invasion and migration of colorectal cancer cells partially dependent on HSPA5 transactivation

https://doi.org/10.18632/oncotarget.8419

Xiaoyong Luo, Jinke Yao, Peipei Nie, Zhiyuan Yang, Hongbo Feng, Pinjia Chen, Xinpeng Shi,  and Zhengzhi Zou
26480-26495
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs

Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs

https://doi.org/10.18632/oncotarget.8420

Diana Rose E. Ranoa, Akash D. Parekh, Sean P. Pitroda, Xiaona Huang, Thomas Darga, Antony C. Wong, Lei Huang, Jorge Andrade, Jonathan P. Staley, Takashi Satoh, Shizuo Akira, Ralph R. Weichselbaum,  and Nikolai N. Khodarev
26496-26515
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-520g promotes epithelial ovarian cancer progression and chemoresistance via DAPK2 repression

MicroRNA-520g promotes epithelial ovarian cancer progression and chemoresistance via DAPK2 repression

https://doi.org/10.18632/oncotarget.8530

Jing Zhang, Lei Liu, Yunyan Sun, Jiandong Xiang, Dongmei Zhou, Li Wang, Huali Xu, Xiaoming Yang, Na Du, Meng Zhang, Qin Yan,  and Xiaowei Xi
26516-26534
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Anti-cancer effects of curcumin on lung cancer through the inhibition of EZH2 and NOTCH1

Anti-cancer effects of curcumin on lung cancer through the inhibition of EZH2 and NOTCH1

https://doi.org/10.18632/oncotarget.8532

Guo-Qing Wu, Ke-Qun Chai, Xiu-Ming Zhu, Hua Jiang, Xiao Wang, Qian Xue, Ai-Hong Zheng, Hong-Ying Zhou, Yun Chen, Xiao-Chen Chen, Jian-Yong Xiao, Xu-Hua Ying, Fu-Wei Wang, Tao Rui, Yi-Ji Liao, Dan Xie, Li-Qin Lu,  and Dong-Sheng Huang
26535-26550
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level

The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level

https://doi.org/10.18632/oncotarget.8437

Natthakan Thongon, Ilaria Castiglioni, Chiara Zucal, Elisa Latorre, Vito D'Agostino, Inga Bauer, Michael Pancher, Alberto Ballestrero, Georg Feldmann, Alessio Nencioni,  and Alessandro Provenzani
26551-26566
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Establishment of prostate cancer spheres from a prostate cancer cell line after phenethyl isothiocyanate treatment and discovery of androgen-dependent reversible differentiation between sphere and neuroendocrine cells

Establishment of prostate cancer spheres from a prostate cancer cell line after phenethyl isothiocyanate treatment and discovery of androgen-dependent reversible differentiation between sphere and neuroendocrine cells

https://doi.org/10.18632/oncotarget.8440

Yamei Chen, Shundong Cang, Liying Han, Christina Liu, Patrick Yang, Zeeshan Solangi, Quanyi Lu, Delong Liu,  and J.W. Chiao
26567-26579
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Salinomycin exerts anti-angiogenic and anti-tumorigenic activities by inhibiting vascular endothelial growth factor receptor 2-mediated angiogenesis

Salinomycin exerts anti-angiogenic and anti-tumorigenic activities by inhibiting vascular endothelial growth factor receptor 2-mediated angiogenesis

https://doi.org/10.18632/oncotarget.8555

Tao Li, Xiaoxia Liu, Qin Shen, Wenjun Yang, Zhenghao Huo, Qilun Liu, Haiyan Jiao,  and Jing Chen
26580-26592
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-429 reverses epithelial-mesenchymal transition by restoring E-cadherin expression in bladder cancer

MiR-429 reverses epithelial-mesenchymal transition by restoring E-cadherin expression in bladder cancer

https://doi.org/10.18632/oncotarget.8557

Chia-Lun Wu, Jar-Yi Ho, Sheng-Chieh Chou,  and Dah-Shyong Yu
26593-26603
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PDZ binding kinase (PBK) is a theranostic target for nasopharyngeal carcinoma: driving tumor growth via ROS signaling and correlating with patient survival

PDZ binding kinase (PBK) is a theranostic target for nasopharyngeal carcinoma: driving tumor growth via ROS signaling and correlating with patient survival

https://doi.org/10.18632/oncotarget.8445

Meng-Yao Wang, Zhi-Rui Lin, Yun Cao, Li-Sheng Zheng, Li-Xia Peng, Rui Sun, Dong-Fang Meng, Ping Xie, Jun-Ping Yang, Li Cao, Liang Xu, Bi-Jun Huang,  and Chao-Nan Qian
26604-26616
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dietary intake of flavonoid subclasses and risk of colorectal cancer: evidence from population studies

Dietary intake of flavonoid subclasses and risk of colorectal cancer: evidence from population studies

https://doi.org/10.18632/oncotarget.8562

Xingkang He,  and Lei-min Sun
26617-26627
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles

Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles

https://doi.org/10.18632/oncotarget.8427

Anja E. Eisenhardt, Adrian Sprenger, Michael Röring, Ricarda Herr, Florian Weinberg, Martin Köhler, Sandra Braun, Joachim Orth, Britta Diedrich, Ulrike Lanner, Natalja Tscherwinski, Simon Tscherwinski, Simon Schuster, Nicolas Dumaz, Enrico Schmidt, Ralf Baumeister, Andreas Schlosser, Jörn Dengjel,  and Tilman Brummer
26628-26652
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High fat diet increases melanoma cell growth in the bone marrow by inducing osteopontin and interleukin 6

High fat diet increases melanoma cell growth in the bone marrow by inducing osteopontin and interleukin 6

https://doi.org/10.18632/oncotarget.8474

Guang-Liang Chen, Yubin Luo, Daniel Eriksson, Xianyi Meng, Cheng Qian, Tobias Bäuerle, Xiao-Xiang Chen, Georg Schett,  and Aline Bozec
26653-26669
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cytotoxic T lymphocyte antigen-4 expression in esophageal carcinoma: implications for prognosis

Cytotoxic T lymphocyte antigen-4 expression in esophageal carcinoma: implications for prognosis

https://doi.org/10.18632/oncotarget.8476

Xiao-Fei Zhang, Ke Pan, De-Sheng Weng, Chang-Long Chen, Qi-Jing Wang, Jing-Jing Zhao, Qiu-Zhong Pan, Qing Liu, Shan-Shan Jiang, Yong-Qiang Li, Hong-Xia Zhang,  and Jian-Chuan Xia
26670-26679
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Emerging roles of circRNA_001569 targeting miR-145 in the proliferation and invasion of colorectal cancer

Emerging roles of circRNA_001569 targeting miR-145 in the proliferation and invasion of colorectal cancer

https://doi.org/10.18632/oncotarget.8589

Huijun Xie, Xiaoli Ren, Sainan Xin, Xiaoliang Lan, Guifeng Lu, Yuan Lin, Shaoshan Yang, Zhicheng Zeng, Wenting Liao, Yan-Qing Ding,  and Li Liang
26680-26691
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PRG3 induces Ras-dependent oncogenic cooperation in gliomas

PRG3 induces Ras-dependent oncogenic cooperation in gliomas

https://doi.org/10.18632/oncotarget.8592

Zheng Fan, Philipp Bittermann-Rummel, Eduard Yakubov, Daishi Chen, Thomas Broggini, Tina Sehm, Gökce Hatipoglu Majernik, Stefan W. Hock, Marc Schwarz, Tobias Engelhorn, Arnd Doerfler, Michael Buchfelder, Ilker Y. Eyupoglu,  and Nicolai E. Savaskan
26692-26708
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Interview with Dr. Nic Savaskan  |  Order a Reprint

Identification of galectin-1 as a novel mediator for chemoresistance in chronic myeloid leukemia cells

Identification of galectin-1 as a novel mediator for chemoresistance in chronic myeloid leukemia cells

https://doi.org/10.18632/oncotarget.8489

Wu Luo, Li Song, Xi-Lei Chen, Xiang-Feng Zeng, Jian-Zhang Wu, Cai-Rong Zhu, Tao Huang, Xiang-Peng Tan, Xiao-Mian Lin, Qi Yang, Ji-Zhong Wang, Xiao-Kun Li,  and Xiao-Ping Wu
26709-26723
Abstract  |  PDF  |  HTML  |  Order a Reprint

Analysis of tumor template from multiple compartments in a blood sample provides complementary access to peripheral tumor biomarkers

Analysis of tumor template from multiple compartments in a blood sample provides complementary access to peripheral tumor biomarkers

https://doi.org/10.18632/oncotarget.8494

William M. Strauss, Chris Carter, Jill Simmons, Erich Klem, Nathan Goodman, Behrad Vahidi, Juan Romero, Michael Masterman-Smith, Ruth O'Regan, Keerthi Gogineni, Lee Schwartzberg, Laura K. Austin, Paul W. Dempsey,  and Massimo Cristofanilli
26724-26738
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Development of a prediction model for radiosensitivity using the expression values of genes and long non-coding RNAs

Development of a prediction model for radiosensitivity using the expression values of genes and long non-coding RNAs

https://doi.org/10.18632/oncotarget.8496

Wei-An Wang, Liang-Chuan Lai, Mong-Hsun Tsai, Tzu-Pin Lu,  and Eric Y. Chuang
26739-26750
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Storkhead box 2 and melanoma inhibitory activity promote oral squamous cell carcinoma progression

Storkhead box 2 and melanoma inhibitory activity promote oral squamous cell carcinoma progression

https://doi.org/10.18632/oncotarget.8495

Tomonori Sasahira, Yukiko Nishiguchi, Rina Fujiwara, Miyako Kurihara, Tadaaki Kirita, Anja Katrin Bosserhoff,  and Hiroki Kuniyasu
26751-26764
Abstract  |  PDF  |  HTML  |  Order a Reprint

Downregulation of ATOH8 induced by EBV-encoded LMP1 contributes to the malignant phenotype of nasopharyngeal carcinoma

Downregulation of ATOH8 induced by EBV-encoded LMP1 contributes to the malignant phenotype of nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.8503

Zifeng Wang, Jiajun Xie, Min Yan, Jing Wang, Xi Wang, Jialiang Zhang, Yan Zhang, Pengfei Li, Xinxing Lei, Qitao Huang, Suxia Lin, Xiang Guo,  and Quentin Liu
26765-26779
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumor suppressor PRSS8 targets Sphk1/S1P/Stat3/Akt signaling in colorectal cancer

Tumor suppressor PRSS8 targets Sphk1/S1P/Stat3/Akt signaling in colorectal cancer

https://doi.org/10.18632/oncotarget.8511

Yonghua Bao, Kai Li, Yongchen Guo, Qian Wang, Zexin Li, Yiqiong Yang, Zhiguo Chen, Jianguo Wang, Weixing Zhao, Huijuan Zhang, Jiwang Chen, Huali Dong, Kui Shen, Alan M. Diamond,  and Wancai Yang
26780-26792
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cdc2-like kinase 2 is a key regulator of the cell cycle via FOXO3a/p27 in glioblastoma

Cdc2-like kinase 2 is a key regulator of the cell cycle via FOXO3a/p27 in glioblastoma

https://doi.org/10.18632/oncotarget.8471

Soon Young Park, Yuji Piao, Craig Thomas, Gregory N. Fuller,  and John F. de Groot
26793-26805
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Matrix metalloproteinase-10 regulates stemness of ovarian cancer stem-like cells by activation of canonical Wnt signaling and can be a target of chemotherapy-resistant ovarian cancer

Matrix metalloproteinase-10 regulates stemness of ovarian cancer stem-like cells by activation of canonical Wnt signaling and can be a target of chemotherapy-resistant ovarian cancer

https://doi.org/10.18632/oncotarget.8645

Tasuku Mariya, Yoshihiko Hirohashi, Toshihiko Torigoe, Yuta Tabuchi, Takuya Asano, Hiroshi Saijo, Takafumi Kuroda, Kazuyo Yasuda, Masahito Mizuuchi, Tsuyoshi Saito,  and Noriyuki Sato
26806-26822
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Predictive and prognostic value of preoperative serum tumor markers is EGFR mutation-specific in resectable non-small-cell lung cancer

Predictive and prognostic value of preoperative serum tumor markers is EGFR mutation-specific in resectable non-small-cell lung cancer

https://doi.org/10.18632/oncotarget.8662

Richeng Jiang, Xinyue Wang,  and Kai Li
26823-26836
Abstract  |  PDF  |  HTML  |  Order a Reprint

RNF4-mediated SUMOylation is essential for NDRG2 suppression of lung adenocarcinoma

RNF4-mediated SUMOylation is essential for NDRG2 suppression of lung adenocarcinoma

https://doi.org/10.18632/oncotarget.8663

Jicheng Tantai, Xufeng Pan,  and Dingzhong Hu
26837-26843
Abstract  |  PDF  |  HTML  |  Order a Reprint

Critical role of DEK and its regulation in tumorigenesis and metastasis of hepatocellular carcinoma

Critical role of DEK and its regulation in tumorigenesis and metastasis of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.8565

Le Yu, Xiaobin Huang, Wenfa Zhang, Huakan Zhao, Gang Wu, Fenglin Lv, Lei Shi,  and Yong Teng
26844-26855
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The prognosis after contraindicated surgery of NSCLC patients with malignant pleural effusion (M1a) may be better than expected

The prognosis after contraindicated surgery of NSCLC patients with malignant pleural effusion (M1a) may be better than expected

https://doi.org/10.18632/oncotarget.8566

Yijiu Ren, Chenyang Dai, Jianfei Shen, Yang Liu, Dong Xie, Hui Zheng, Jiaxi He, Wenhua Liang, Gening Jiang, Ke Fei, Ping Yang, Jianxing He,  and Chang Chen
26856-26865
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of novel microRNAs regulating HLA-G expression and investigating their clinical relevance in renal cell carcinoma

Identification of novel microRNAs regulating HLA-G expression and investigating their clinical relevance in renal cell carcinoma

https://doi.org/10.18632/oncotarget.8567

Simon Jasinski-Bergner, Adi Reches, Christine Stoehr, Chiara Massa, Evamaria Gonschorek, Stefan Huettelmaier, Juliane Braun, Sven Wach, Bernd Wullich, Verena Spath, Ena Wang, Francesco M. Marincola, Ofer Mandelboim, Arndt Hartmann,  and Barbara Seliger
26866-26878
Abstract  |  PDF  |  HTML  |  Order a Reprint

Oligometastatic state predicts a favorable outcome for renal cell carcinoma patients with bone metastasis under the treatment of sunitinib

Oligometastatic state predicts a favorable outcome for renal cell carcinoma patients with bone metastasis under the treatment of sunitinib

https://doi.org/10.18632/oncotarget.8568

Xiaolin Lu, Weijie Gu, Hailiang Zhang, Yao Zhu, Guohai Shi,  and Dingwei Ye
26879-26887
Abstract  |  PDF  |  HTML  |  Order a Reprint

Combined gemcitabine and S-1 chemotherapy for treating unresectable hilar cholangiocarcinoma: a randomized open-label clinical trial

Combined gemcitabine and S-1 chemotherapy for treating unresectable hilar cholangiocarcinoma: a randomized open-label clinical trial

https://doi.org/10.18632/oncotarget.8590

Hao Li, Zheng-Yun Zhang, Zun-Qiang Zhou, Jiao Guan, Da-Nian Tong,  and Guang-Wen Zhou
26888-26897
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The physical interaction of p53 and plakoglobin is necessary for their synergistic inhibition of migration and invasion

The physical interaction of p53 and plakoglobin is necessary for their synergistic inhibition of migration and invasion

https://doi.org/10.18632/oncotarget.8616

Mahsa Alaee, Amarjot Padda, Vahedah Mehrabani, Lucas Churchill,  and Manijeh Pasdar
26898-26915
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Prognostic models to predict survival in patients with advanced non-small cell lung cancer treated with first-line chemo- or targeted therapy

Prognostic models to predict survival in patients with advanced non-small cell lung cancer treated with first-line chemo- or targeted therapy

https://doi.org/10.18632/oncotarget.8309

Rossana Berardi, Silvia Rinaldi, Matteo Santoni, Thomas Newsom-Davis, Michela Tiberi, Francesca Morgese, Miriam Caramanti, Agnese Savini, Consuelo Ferrini, Mariangela Torniai, Ilaria Fiordoliva, Marc Bower,  and Stefano Cascinu
26916-26924
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Corrections

Correction: RKIP regulates CCL5 expression to inhibit breast cancer invasion and metastasis by controlling macrophage infiltration

Correction: RKIP regulates CCL5 expression to inhibit breast cancer invasion and metastasis by controlling macrophage infiltration

https://doi.org/10.18632/oncotarget.9139

Ila Datar, Xiaoliang Qiu, Hong Zhi Ma, Miranda Yeung, Shweta Aras, Ivana de la Serna, Fahd Al-Mulla, Tuan Zea Tan, Jean Paul Thiery, Robert Trumbly, Fan Xuan, Hongjuan Cui,  and Kam C. Yeung
26925
Correction  |  PDF


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